Synopsis: Domenii: Health: Health generale: Illness: Cancer, neoplasms and tumors: Cancer:


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#Big data driving market disruption, leaving many organizations fearing irrelevance: Study A global report by Capgemini, provider of consulting, technology and outsourcing services, in partnership with EMC Corporation, reveals that amid the market disruption being driven by Big data,


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#Vaccine might replace surgery for cervical cancer A genetically engineered cervical cancer vaccine performed well in a clinical trial,

and can lead to cervical cancer, according to the US Centers for Disease Control and Infection. very standard therapeutic option for women with these lesions destroys part of the cervix,

Despite dramatic progress in recent decades, about 12,000 women still develop cervical cancer in the United states each year, and about 4

Because the lesions can progress to cancer, they are removed today usually by surgery, freezing, or laser treatment.

They pose less of a cancer risk and usually regress on their own. CLEARS OUT THE VIRUS

the slow development of cervical cancer would leave an opening for patients to try it. t typically takes about 10

or more years for precancerous cells to become cancer, so there is a window of opportunity to intervene with nonsurgical approaches,

She is also studying other types of vaccines to prevent high-grade cervical lesions from developing into cancer.


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Although intralesional IL-2 has recently been included in the US National Comprehensive Cancer Network guidelines for management of melanoma metastases of the skin


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and demonstrate for opioid pain relievers can be adapted to produce many plant-derived compounds to fight cancers,


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and easily repeatable test for pancreatic cancer, scientists at Barts Cancer Institute, Queen Mary University, have developed a three-protein biomarker panel that can screen urine samples to identify pancreatic cancer

Patients suffering from chronic pancreatitis had significantly lower levels than cancer patients. Combining the three proteins

The panel performance was described August 3 in the journal Clinical Cancer Research, in an article entitled, dentification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma. hen comparing

The biomarker panel established by the Barts Cancer Institute scientists, however, shows promise. e've always been keen to develop a diagnostic test in urine as it has several advantages over using blood.

if the three-biomarker signature is present during the latency periodhe time between the genetic changes that will cause the cancer to develop and the clinical presentation.

when the cancer has already spread. This means they are not eligible for surgery to remove the tumorurrently the only potentially curative treatment.

when the cancer is already at a terminal stage, but if diagnosed at stage II,


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or even cancer in minutes from the comfort and privacy of your home sound like science fiction?


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Surprisingly, this same residue has been seen to cluster on the surface of various cancers. Now a collaborative team of researchers from the Translational Genomics Research Institute (TGEN), University of Copenhagen, University of British columbia (UBC), Vancouver Coastal Health and the BC Cancer Agency, found that the malaria protein,

called VAR2CSA, could be used to target anticancer drugs and carry them to tumors expressing the specific carbohydrate residue."

and lung cancers,"explained co-author Nhan Tran, Ph d.,associate professor in TGEN's Cancer and Cell biology Division."

"The findings from this study were published recently in Cancer cell through an article entitled argeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein."

"Scientists have spent decades trying to find biochemical similarities between placenta tissue and cancer, but we just didn't have the technology to find it,"noted project leader Mads Daugaard, Ph d.,assistant professor of urologic science at UBC and a senior research scientist at the Vancouver Prostate Centre, part of the Vancouver Coastal

"This is an extraordinary finding that paves the way for targeting sugar molecules in pediatric and adulthood human cancer,


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and scientists in the field quickly detect certain types of cancer or bacterial and respiratory infections or monitor toxin levels in water.

which is a marker for cancer, "Brennan explained.""We can print the letter'A'for ATP and'P'for PDGF,


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and for clinical assessment of different types of cancer,"said Carnegie mellon president Subra Suresh. With the speed improvements in mind, the method is now approaching a state viable for widespread medical use.


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#Modified Salmonella eats away at cancer, without a side order of food poisoning Though generally a bacteria we'd associate with a severe bout of food poisoning,


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what works with food also works with other things, like creating new pharmaceuticals and cancer-fighting proteins.


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#Tadpole-like endoscope swims through gastrointestinal tract in search of cancer Endoscopes are essential tools for the medical examination of many organs of the human body,

With cancers of the gastrointestinal (GI TRACT such as esophageal cancer, stomach cancer, and colon cancer, being some of the most commmon of all cancers in the world,

a range of procedures are necessary to physically examine all parts of the GI for maximum diagnostic effect.

Of these, gastroscopy is used to help diagnose esophageal and stomach cancer, whilst intestinal and coleorectal cancers can be determined with the use of capsule endoscopy and colonoscopy, respectively.

Unfortunately, all of these procedures are costly to perform and can place a great deal of stress on someone who may already be quite ill.

The new Tadpole Endoscope (TE on the other hand, is a relatively noninvasive device that is simply swallowed like a large pill


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#5-yr Study Reveals Why Ovarian Cancer Recurs and How to Stop It Scientists have discovered finally why ovarian cancer frequently comes back after patients receive chemotherapynd theye also found a way to potentially eliminate the recurrence rate for half of patients who have the disease.

A five-year study at the University of California at Los angeles found that coupling chemotherapy with an experimental drug called Birinapant greatly improved survivability in laboratory tissue.

At the core of the problem is the way doctors test for ovarian cancer. One of the things they look for is called a protein CA125.

Chemotherapy targets cells containing the protein and that knocks out the cancer. The UCLA researchers found other cells

allowing ovarian cancer to recur in more than 80%of people treated with chemotherapy alone. e found that these cells were like little time bombs,

the combined treatment attacks the cancer on both fronts. Ebola Suit-Liberia-USAID-CC-Morganawingard-adjusted The researchers plan clinical trials on actual patients next.

Not everyone with ovarian cancer would benefit from this particular combination of therapies. The good news is these two types of cells are present in about 50%of ovarian cancer patients who would be candidates for this dual treatment.

Researchers are looking at other biomarkers to see if theye been missing still other hidden cancer ime bombs. og-nose-cancer-Photo-credit-Itsgreg-CC-750px The study was funded by grants from 10 foundations

and government agencies and was published on August 3 in the journal Nature h


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#Teenage Girl Turns Plastic Trash Into Million-Dollar Biofuel An Egyptian teenager has discovered an inexpensive way to turn plastic trash into fuel


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How We Might Starve Tumors by Cutting off Food supply In their hunger to find ways to cure cancer,

They found that cancers with low PAT4 levels grew more slowly while patients that showed higher levels had more trouble fighting tumors and a higher chance of remission.

traditional cancer treatments to fight the disease more effectively. The research, published today in the science journal Oncogene,

was funded by Cancer Research UK, the Wellcome Trust and the Biotechnology and Biological sciences Research Council h


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According to the researchers, thousands of men and even young boys rendered infertile by cancer and other diseases could benefit. his breakthrough opens the way for therapeutic avenues that have been awaited eagerly by clinicians for many years,

Yet more than 15,000 young cancer patients are affected throughout the world. Nor is there any solution for the 120,000 adult men who suffer from infertility that cannot be treated using existing technologies.


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The number of years lived with disability have increased in almost every country, attributable to the growth of chronic diseases such as cardiovascular and respiratory diseases, cancer, back pain, mental health disorders, dementia, road injuries, HIV


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romidepsin-a drug currently being used to treat cancer-to be the most potent, and thus successful, inhibitor trialled so far.


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#Patients Will Swallow 3d printed Tadpole Endoscope That Provides Diagnosis of Cancers A team from the Institute of Precision Engineering at the Chinese University of Hong kong has developed 3d printed tadpole-like devices that can improve diagnosis

of various cancers by entering the patient stomach and wirelessly transmitting images of what it sees.

and relatively noninvasive solution that could improve cancer diagnosis. Developed to be swallowed just like a large pill (it is a bit bigger than a small coin),


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and Genistein, the compound found in soybean which has been suggested to play a role in prevention of steroid-hormone related cancers, particularly breast cancer.


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and Genistein, the compound found in soybean which has been suggested to play a role in prevention of steroid-hormone related cancers, particularly breast cancer.


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#Cancer Tech: New Devices Could Speed up Treatment Treating cancer is sometimes a process of trial and error,

because any given drug or drug combination does not work the same for all patients.

In Seattle, researchers at the Fred Hutchinson Cancer Research center and the company Presage Biosciences designed a device called CIVO that includes up to eight needles arranged in an array.

if the cancer is resistant"to the drug that's being prescribed, said Dr. James Olson,

Top 10 Cancer-Fighting Foods With CIVO, doctors"can compare drug A to drug B,

which are cancers of the lymph system, and had enlarged lymph nodes. The patients said they had very little pain with the injections, according to the report.

and a small amount of the cancer tissue around it. As with CIVO, the aim is to let doctors look at the cancerous tissue,

But the implant offers a way to attack cancers that are deeper in the body and thus less accessible to injections.

and the patient would avoid enduring the side effects of drugs that wouldn't end up treating the cancer."

and the MIT researchers'work was funded by the National Cancer Institute and Massachusetts-based biotech company Kibur Medical.


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the late American film critic who lost his jawbone to cancer, is autograft. This is basically a euphemism for cutting a piece of bone out of one part of the body


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But a chance meeting between Petri and a bladder cancer expert, Dr. Dan Theodorescu, who is director of the University of Colorado Cancer Center,

or more effective in killing the cancer. Petri merely substituted E. histolytica for a drug.

"What's an ameba have to do with cancer, after all?""Theodorescu said. But recently the two were working together, on a hiring committee,


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But a chance meeting between Petri and a bladder cancer expert, Dr. Dan Theodorescu, who is director of the University of Colorado Cancer Center,

or more effective in killing the cancer. The 10 Most Diabolical and Disgusting Parasites Petri merely substituted E. histolytica for a drug.

"What's an ameba have to do with cancer, after all?""Theodorescu said. Tiny & Nasty: Images of Things That Make Us Sick


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#New Blood test Predicts Breast cancer Relapse Months In advance (VIDEO) Researchers from The Institute of Cancer Research in London have developed a new blood test,


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and successfully did a small cancer gene study using this technique. The group was able to add a few modified cells with the Rasg12v cancer gene in a printed organoid array

and observed how the few mutated cells were able to induce a response from its surrounding tissue.


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#Mobileodt Brings Cervical cancer Diagnostics to Developing Countries Early detection significantly improves the survival rates for cervical cancer patients.

Cervical cancer used to be one of the leading causes of cancer deaths in the US,

but mortality rates have declined significantly in the last 40 years due in part to better compliance with regular cervical cancer screening.

and has leveraged this into a new cervical cancer screening product. Their cervical cancer screening system allows any smartphone to be turned into a colposcope,

making this part of the screening process readily available for most clinics. The hardware is equipped with a light source


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and a member of MIT Koch Institute for Integrative Cancer Research, is the paper senior author.


R_www.nanomagazine.co.uk_category&id=172&Itemid=158 2015 00228.txt.txt

and cancer drugs Longing to find a cure for cancer, HIV and other yet incurable diseases,

hepatitis and cancer. The research, led by Yury Stebunov, a scientist at the MIPT, was published in the ACS Applied materials & Interfaces.

and low-cost fabrication compared to sensor chips that are already commercially available. ur invention will help in drug development against viral and cancer diseases.


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, 2015curcumin Nanodrug Breaks Cancers'Resistance to Treatment May 10th, 2015discoveries First theoretical proof: Measurement of a single nuclear spin in biological samples May 11th, 2015graphene holds key to unlocking creation of wearable electronic devices May 11th, 2015new Method to Produce Dual Zinc oxide Nanorings May 11th

, 2015curcumin Nanodrug Breaks Cancers'Resistance to Treatment May 10th, 2015announcements First theoretical proof: Measurement of a single nuclear spin in biological samples May 11th, 2015graphene holds key to unlocking creation of wearable electronic devices May 11th, 2015new Method to Produce Dual Zinc oxide Nanorings May 11th

, 2015curcumin Nanodrug Breaks Cancers'Resistance to Treatment May 10th, 2015interviews/Book reviews/Essays/Reports/Podcasts/Journals/White papers First theoretical proof:

, 2015curcumin Nanodrug Breaks Cancers'Resistance to Treatment May 10th, 2015artificial Intelligence Making robots more human April 29th, 2015lifeboat Foundation launches Interactive Friendly AI April 6th,


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#Gold-diamond nanodevice for hyperlocalised cancer therapy: Gold nanorods can be used as remote controlled nanoheaters delivering the right amount of thermal treatment to cancer cells,

which can potentially be applied to thermal cancer therapy. Pei-Chang Tsai from the Institute of Atomic and Molecular Sciences, at the Academia Sinica, Taipei,


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#Advance in photodynamic therapy offers new approach to ovarian cancer The findings were published just in the journal Nanomedicine:

and after further research may offer a novel mechanism to address this aggressive and often fatal cancer that kills 14,000 women in the United states each year.

Ovarian cancer has a high mortality rate because it often has metastasized into the abdominal cavity before it's discovered.

"Surgery and chemotherapy are the traditional approaches to ovarian cancer, but it's very difficult to identify all of the places where a tumor has spread,

there was no evidence of cancer recurrence. During the procedures, mice receiving the gene therapy also continued to grow

is associated with invasion, metastasis, resistance to cancer therapies, and overall cancer cell survival. That excess of DJ1 is silenced by the genetic therapy composed of sirna.

"Our study established a prospective therapeutic approach against ovarian cancer, "the researchers wrote in their conclusion."


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it also has broad implications for targeted therapy for other diseases such as cancer and neurological disorders,"said Chien.


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The aim of the research was to facilitate the diagnosis of cancer tumors, including breast cancer, without the need for advanced clinical devices.

It means a non-consistency happens in the profile received from the interaction of emitted light and various healthy and cancer tissues.


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may aid efforts to build point-of-care devices for quick medical diagnosis of various diseases ranging from cancer, allergies, autoimmune diseases, sexually transmitted diseases (STDS),


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#Scientists pave way for diamonds to trace early cancers Physicists from the University of Sydney have devised a way to use diamonds to identify cancerous tumours before they become life threatening.

synthetic version of the precious gem can light up early-stage cancers in nontoxic, noninvasive Magnetic resonance imaging (MRI) scans.

Targeting cancers with tailored chemicals is not new but scientists struggle to detect where these chemicals go since,

if a treatment has been taken up by a cancer. Led by Professor David Reilly from the School of Physics

researchers from the University investigated how nanoscale diamonds could help identify cancers in their earliest stages."

"By attaching hyperpolarised diamonds to molecules targeting cancers the technique can allow tracking of the molecules'movement in the body,

and target cancers long before they become life-threatening, "says Professor Reilly. The next stage of the team's work involves working with medical researchers to test the new technology on animals.


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The aim of the research was to design an effective system to diagnose blood cancer (leukemia) by using gold nanobars.


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SNAS could be used to target anything from influenza to different forms of cancer. They also can be used to suppress the immune response

"Once developed fully, SNAS will lay the foundation for developing an entire new pipeline of drugs to treat a range of diseases, from psoriasis, lupus and rheumatoid arthritis to lymphoma, bladder cancer and prostate cancer."

This observation has significant implications for treating liver cancer and cirrhosis patients.""The beauty of the approach is that a very small amount of drug does a tremendous amount of work,


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in the effectiveness of current cancer medicines in lung tumour tissue. Tumor tissue in the lung.


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#High-tech method allows rapid imaging of functions in living brain Researchers studying cancer and other invasive diseases rely on high-resolution imaging to see tumors and other activity deep within the body's tissues.

Given the importance of oxygen metabolism in basic biology and diseases such as diabetes and cancer,


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#Scientists use nanotechnology to visualize potential brain cancer treatments in real time (Nanowerk News) Virginia Tech Carilion Research Institute scientists have developed new imaging techniques to watch dangerous brain tumor

and describes how the research team used nanotechnology to watch tumor stem cells respond to therapy. ee never been able to directly observe the actions of potential cancer treatments this way before,

a cancer biologist and an assistant professor of biomedical sciences and pathobiology at the Virginiaaryland College of Veterinary medicine. t was astounding.

Glioblastoma is a brain cancer with a poor prognosis. Even with surgical interventions or traditional treatments

what is used in some cancer treatments and watched the process in cell cultures using in situ transmission electron microscopy.

or even test new cancer treatments at the cellular level, Kelly said. Sheng pointed to another characteristic that makes cancer cells difficult to treat:

In the same cancer population, even neighboring cells can differ drastically, and each cell can respond to treatments differently. e can look at single-cell delivery of cancer treatments,

and see how the individual cells respond, Sheng said. f we can learn how to kill these cells,


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#Quick, easy and early diagnosis with rare earth ions Lack of oxygen in cells is an indicator of diseases as serious as cerebral haemorrhages, stroke and cancer.


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#Molecular tinkering doubles cancer drug's efficacy The drug paclitaxel has been used for decades to fight breast, ovarian, lung and other cancers.

The results were published online in Nature Communications on August 4, 2015("A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models".

it could be a game-changer for cancer therapy.""In future work, Chilkoti and coworkers will begin applying the packaging system to other cancer drugs with the goal of developing a"one size fits all"technology to improve the effectiveness of many other cancer drugs s


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or some cancer treatments, and can lead to a significantly higher risk of infections, and the need for blood transfusions.


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and cancer drugs Longing to find a cure for cancer, HIV and other yet incurable diseases,

hepatitis and cancer. The research, led by Yury Stebunov, a scientist at the MIPT, was published in the ACS Applied materials

"Our invention will help in drug development against viral and cancer diseases. We are expecting that pharmaceutical industry will express a strong demand for our technology,


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"may aid efforts to build point-of-care devices for quick medical diagnosis of various diseases ranging from cancer, allergies, autoimmune diseases, sexually transmitted diseases (STDS),


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The researchers say this approach also could be used for vaccines or immunotherapies for other conditions such as cancer or AIDS o


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Future applications of such a DNA walker might include a cancer detector that could roam the human body searching for cancerous cells

constantly computing whether a cancer is present.""More immediate practical applications may include deploying the DNA walker in the body

Although it may be a long march from diagnosing cancer to curing it, "All breakthroughs begin with baby steps.


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and now is in the Chemical Biology laboratory at the National Cancer Institute. Also part of the study were researchers from Johns hopkins university School of medicine

using a transmission electron microscope at the National Cancer Institute to show how the fibers change


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So just as nude mice can be really good models for cancer research, 'nude'versions of crop plants could also speed up agricultural research,


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#How Chronic Inflammation Can Lead to Cancer Researchers discover how the immune system can create cancerous DNA mutations when fighting off infection.

or exposure to dangerous chemicals has long been linked to cancer, but exactly how this process takes place has remained unclear.

Now, a precise mechanism by which chronic inflammation can lead to cancer has been uncovered by researchers at MIT a development that could lead to improved targets for preventing future tumors.

the researchers unveil how one of a battery of chemical warfare agents used by the immune system to fight off infection can itself create DNA mutations that lead to cancer.

As many as one in five cancers are believed to be caused or promoted by inflammation. These include mesothelioma,

are the kind of lesions that would initiate cancer, he adds. DNA sequencing of a developing gastrointestinal tumor revealed two types of mutation:

he explains. his scenario would best explain the work of James Fox and his MIT colleagues on gastrointestinal cancer.

says the paper provides a novel mechanistic link between chronic inflammation and cancer development. ith a combination of biochemical, genetic,

a type of mutation that is frequently observed in human cancers, Wang says. Studies of tissue samples of patients suffering from inflammatory bowel disease have found significant levels of 5clc,

who was honored with the prestigious Benjamin F. Trump award at the 2015 Aspen Cancer Conference for the research.


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researchers have recently been able to develop precise treatments for cancer by sequencing tumor genomes


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#Researchers Identify Protein That Opens the Door to Cell Death Findings could aid development of novel therapeutics for conditions ranging from heart failure and stroke to cancer and neurodegeneration.

Dr. Madesh also explained that the new findings could aid the development of novel therapeutics for conditions ranging from heart failure and stroke to cancer and neurodegeneration all of


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but also for regulating the inflammatory responses that may result in autoimmune diseases. his finding could be helpful for developing strategies to target cancer

the immune cells that play dual roles in the development of autoimmune diseases and the destruction of cancers.

either hone the pathway cancer-killing role or reduce its role in inflammation


R_www.neurosciencenews.com_neuroscience-topics 2015 00897.txt.txt

#Key Morphine Regulator That May Reduce Risk of Pain killer Addiction Identified Once used in the 18th century as currency to reverse the trade imbalance between China and Britain,


R_www.neurosciencenews.com_neuroscience-topics 2015 01027.txt.txt

#Uncovering Clues About Abnormal Embryo Development with Artificial intelligence Melanoma-like cells in tadpoles may mimic variability in human responses to cancer stimuli.

His brother, leading a similar lifestyle, succumbs to cancer at age 55. Why do some individuals develop certain diseases

which may mimic the variability in human responses to cancer-inducing stimuli, said Levin. Furthermore, the tadpoles that did develop melanoma developed it in every pigment cellach frog was either 100 percent metastatic or completely normal.

researchers could use this approach to develop a system to help doctors understand patientsindividual genetic responses to treatments as well as environmental factors that cause cancer.


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#Cancer trap grabs wandering tumour cells to warn of early spread The trouble with cancer is it spreads sometimes even before someone knows they are ill.

Jeruss had noticed how common it was for her patientsfirst symptom to be breathlessness as the cancer had already spread to their lungs.

Gerhardt Attard of the Institute of Cancer Research in London says there is growing interest in personalising cancer treatments by testing cancer cells in the blood. his could be a very powerful way of risk stratifying patients for treatment


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Lumps can be a sign of cancer, of course, and stiffness in certain organs can indicate disease.


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codenamed Big Mechanism, to read all the scientific papers on certain types of cancer and use that knowledge to identify potential treatments.


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And they've already implanted the device into the chest of a 54-year-old cancer patient.


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Cancer tissue, for example, is less dense than healthy tissue. The method therefore opens up the prospect of detecting tumors that are less than 1mm in diameter in an early stage of growth before they spread through the body


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#New uper-Tomatocan Fight Cancer, Heart disease, Diabetes and Alzheimer Scientists said that they have invented a uper-tomatowhich can fight cancer, heart disease, diabetes and Alzheimer.

whereas genistein could help in prevention of some cancers, including breast cancer. The study published in the journal Nature Communications said that the super-tomatoes contain a protein called Atmyb12,


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It our single biggest health problem, affecting the lives of 100 million adults--more than heart disease, cancer,


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#FDA Approves Use Of Engineered Herpes virus To Treat Cancer Yesterday, the Food and Drug Administration (FDA) announced that it had approved the drug Imlygic to treat late-stage melanoma on the skin and lymph nodes.

And while malignant cancers often slip by the immune system, the viruspresence ignites the immune response. Combined, these reactions mean that virology can successfully treat even some late-stage cancers that are often resistant to other treatment methods.

Before it was approved, Imlygic was tested in more than 400 patients with metastatic melanoma, which kills about 10,000 people per year in the United states,

So far, virology treatments haven worked as well in cancers in tissues deeper in the bodyhe drug has to be injected directly into the tumor site

and to treat several types of cancer are already in clinical trials. Now that the first virology cancer treatment has been approved,

researchers hope that many more are to follow e


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