we reported on 3d printed icrofishrobots that can be injected directly into our blood to perform complex medical tasks.
and eventually be implemented successfully in medical applications i
#American Wind turns wind-generated electricy on its head with 3d printed Microcube Aerospace engineer Robert Yost has developed
and could be useful for tissue engineering, providing invaluable aid to neurosurgeons and cancer researchers.
Its applications range from medicine, advanced energy, electronics, aerospace design and many others. Despite these groundbreaking characteristics,
unlike smooth titanium or other biomaterials such as PEEK, has been associated in preclinical data with bone growth (osteoblastic) activity.
"said Tom Morrison, MD, a neurosurgeon at Polaris Spine & Neurosurgery Center in Atlanta, Georgia."I'm excited about the CASCADIA platform
#3d Systems Demos Virtual Surgeries and Soft 3d printed Models in New orleans On top of its massive 3d printing portfolio and Quickparts services, 3d Systems also has an extensive medical design and 3d printing wing.
Today, the company has announced two significant programs that could foreshadow the future of medicine altogether:
the release of irst-ever virtual reality robotic prostatectomy simulation training as well as patient-specific 3d printed kidney models for surgical planning and training, developed in partnership with Tulane University School of medicine.
To step in and train the surgeons that will perform this surgery is 3d Systems with its Robotix Mentor training module.
The Robotix Mentor allows trainees to practice the surgery in a virtual environment using step-by-step guidance, performance metrics, anatomy recognition,
The additional LAP Mentor Express simulator even provides laparoscopic assistants training to aid the primary surgeon in the virtual procedure. 3ds Vice president
he addition of the Prostatectomy Module changes the future of Robotic Urology training. 3d Systems is committed to supporting medical advancements that ultimately affect patient safety by providing innovative products that range from virtual reality training
In addition to their new Robotix system, 3ds has developed also a new series of soft, 3d printed kidney models for surgical training.
the models developed by 3ds in tandem with surgeons at Tulane University School of medicine actually have the texture and consistency of the kidneys on
plan surgeries, or practice procedures before operation. Dr. Jonathan Silberstein, Assistant professor of Urology and Chief of Urologic Oncology at Tulane, says of the technology,
ndividualized patient-specific soft tissue 3d printing allows surgeons and trainees the opportunity to operate on a model that looks
and feels just like their patient kidney tumor. This technology has the potential to reinvent the way we teach
and train our young surgeons and for experienced surgeons adapting to a new technology such as robotics,
it will flatten the learning curve. o me, what these technologies represent, in addition to the future of surgery planning,
is 3d Systemsgrasp of the evolving reality computing ecosystem, which encompasses 3d scanning, 3d printing, VR,
Both pieces of tech will be on display at the Annual Meeting for the American Urological Association in New orleans from today until May 19.
and delivering medicinal products to hard-to-reach places within the body. The leaders of this project, Professors Shoachen Chen and Joseph Wang, recognized that most microrobots that have already been produced are unable to perform more advanced tasks due to their simply-shaped designs and inorganic physical make-ups.
helping medical professionals gather their diagnosis from swimming throughout the body with these microfish. 3d printing enthusiasts are amazed oftentimes by
assess and provide 3d printing of medical supplies where it is needed most, turning the knowledge she acquired to her own field of expertise.
and off-the-shelf components to 3d print medical and dental devices, using either a solar power-charged battery or solar panels as power sources.
and customized medical resources at a Mars analogue research station. This study describes a 3d printer with a PV system improvised on-site by providing a detailed components summary.
Some more doubts may concern the actual efficacy of the medical items that were 3d printed.
and published the results, in collaboration with the University of Aveiro (Portugal), in the Journal of Biomedical Materials Research.
and scaffolds for regenerative biomedicine that will speed up bone regrowth, while the polymer-based support dissolves efficiently.
and Ribs in First of its Kind Surgery Only months after Australia scientific research arm launched its $6 million 3d printing facility,
When a Spanish surgical team made up of Dr José Aranda, Dr Marcelo Jimene and Dr Gonzalo Varela from Salamanca University Hospital decided to remove the patient sternum and part of his rib cage,
and improve their recovery post-surgery. However, 3d printing has been increasingly proven as the ideal method for creating complex, patient-specific implants.
While titanium implants have previously been used in chest surgery, designs have not considered the issues surrounding long term fixation.
which the doctors were better able to plan their surgery and the necessary implant. Batty elaborates
Alex Kingsbury, Research Group Leader of Additive manufacturing at CSIRO, explained the benefits of 3d printing in surgical-grade titanium,
building the product up layer-by-layer until you have a complete implant. 3d printing has significant advantages over traditional manufacturing methods, particularly for biomedical applications.
if a patient is waiting for surgery. The implant was shipped then off to Spain, where it was implanted into the patient.
Minister Macfarlane said. his collaboration crossed disciplines and international boundaries, with a clear benefit for both this individual patient and for surgical practice.
3d printing in the medical sector is climbing towards a peak of hypeability and nothing could be more hype-worthy than the regeneration of nerves after an injury.
and tissues that the surgeons are going to operate on. Other applications include tissue engineering, flexible electronics, particle engineering, smart materials,
Researchers writing recently in The british Dental Journal argue dentists shouldn't remove impacted wisdom teeth that are not giving any symptoms.
Dentists often remove impacted wisdom teeth to avoid the risk of problems such as pain, gum inflammation and decay.
they advise dentists keep a close eye on the teeth to see if they develop problems.
surgery itself can lead to complications such as nerve damage, damage to other teeth, infection, swelling,
by their dentists, to decide whether they want to take the risk of keeping their impacted wisdom teeth.
when you have your wisdom teeth out the more likely you will suffer complications from the surgery,
and will result in an increasing rate of surgical complications. Although, he adds, we won't know
Sudipto Pakrasi, chairman of the ophthalmology division at Medanta, Gurgaon, Haryana, tells Scidev. Net that currently available technologies for detection of glaucoma are expensive
If we detect it early then it is possible to halt the progression of glaucoma by appropriate medications or surgery,
such as ejector pins for iphones, watch springs for expensive hand-wound watches, trial medical implants,
Alternatively, we may see surgeons first applying the nanoneedle bandages inside the affected region to promote the healthy integration of these new organs and implants in the body.
#Microbubble Technology for Delivery of Nanoparticles to Tumours Biomedical researchers led by Dr. Gang Zheng at Princess Margaret Cancer Centre have converted successfully microbubble technology already used in diagnostic imaging into nanoparticles that stay
In the lab in preclinical experiments, the team used low-frequency ultrasound to burst the porphyrin containing bubbles
"says Dr. Zheng, Senior Scientist at the Princess Margaret and also Professor of Medical Biophysics at the University of Toronto.
the presence of an unseen tumor or show whether an infection has developed around a surgical implant."
which GEMS can be employed for biomedical uses.""That would require, among other things, further miniaturization.
That would open up many additional biomedical applications. One of the most significant features of GEMS is that they can be tuned"in fabrication to respond to different biochemical states
New materials for energy application, new concepts for medical surfaces, new surface materials for tribological systems and nano safety and nano bio.
which can be a complication of cataract surgery. The company envisions a wide application of this immunodepletion strategy in other fibrotic diseases and cancer,
a for-profit subsidiary of the Lankenau Institute for Medical Research where an early stage of the technology was developed.
a disease that typically occurs in approximately 30%of adults and greater than 70%of children after cataract surgery.
Additional studies testing this formulation in rabbits undergoing cataract surgery are ongoing with Drs. Liliana Werner and Nick Mamalis, Co-Directors of the Intermountain Ocular Research center at the University of Utah.
and could lead to better technologies for medical diagnostics and chemical purification. A team of Harvard scientists has demonstrated a new way of detecting
Aizenberg said. his new approach holds promise for the next-generation, energy-efficient separation and purification technologies and medical diagnostics.
and produces planetariums, eyeglass lenses, camera and cine lenses and binoculars as well as solutions for biomedical research, medical technology and the semiconductor, automotive and mechanical engineering industries.
thus having the capacity of becoming a standard method of quality control of stem or pluripotent cells before their use in cell therapy or research in biomedicine.
"This advance offers an entirely new approach with which to confront a broad range of problems in fields ranging from energy to medicine."
as they are attached to the skin with a biocompatible, medical-grade adhesive. Users can therefore decide where they want to position the sensor patch
you can provide personalized medicine for their particular disease. There are several issues with the current standard method for sputum analysis. The first is that human specimens can be contagious,
This will allow health care providers to individualize asthma treatments for each patient and advance the goal of bringing precision medicine into clinical practice.
Chen started out as a biochemist working on biomedical devices. After he joined Berkeley Lab around 2000, he learned about quantum dots,
"said Neil Spector, an oncologist at Duke Medicine familiar with the work.""But it's not just the increase in clinical efficacy
processes done in a medical testing lab for example, purifying samples, mixing ingredients, capturing bacteria can be done with material about the size of a deck of cards.
and shared the 2013 Nobel prize in Physiology or Medicine. Thomas C. Südhof, a professor at the Stanford School of medicine and Howard hughes medical institute investigator who shared that 2013 Nobel prize with Rothman,
An international team of researchers, led by Dr Munitta Muthana from the University of Sheffield's Department of Oncology,
This new technology may contribute to medical cost reduction while maintaining the quality of medical treatment.
This study was published in the online version of the academic journal Biomaterials on June 9, 2015.
This new technology may contribute to medical cost reduction while maintaining the quality of medical treatment without using growth factors that are expensive and prone to deactivation.
To promote angiogenesis in body parts where blood flow is poor due to diabetes, research has been conducted to develop materials that absorb growth factors
This technology also may contribute to cost reduction in certain medical treatments. Based on these positive results
the research group intends to engage in collaborative studies with medical and industrial sectors, and aims to expand its activities in the field of regenerative medicine and developing medical devices s
#Microfluidics Technology-Based Lab-on-a-chip Device Could Reduce Cost of Sophisticated Tests for Diseases Rutgers engineers have developed a breakthrough device that can significantly reduce the cost of sophisticated lab tests for medical disorders
#Translational Grant for Interaction Study of Laser radiation with Circulating Tumor Cells and Melanin Nanoparticles University of Arkansas for Medical sciences (UAMS) researcher Vladimir Zharov, Ph d.,D. Sc.
Zharov is director of the Arkansas Nanomedicine Center at the UAMS Winthrop P. Rockefeller Cancer Institute and a professor in the UAMS College of Medicine Department of Otolarynology-Head and Neck Surgery.
certain types of biopsies and surgery can trigger the release of cancer cells from a primary tumor into circulation, increasing CTC counts.
and Neck Surgery in the UAMS College of Medicine UAMS is the state only comprehensive academic health center, with colleges of Medicine, Nursing, Pharmacy, Health professions and Public health;
the Winthrop P. Rockefeller Cancer Institute, the Jackson T. Stephens Spine & Neurosciences Institute, the Myeloma Institute, the Harvey & Bernice Jones Eye Institute, the Psychiatric Research
UAMS has 2, 890 students and 782 medical residents. It is the state largest public employer with more than 10,000 employees,
Now, a team of researchers from the Stowers Institute for Medical Research and the University of Colorado Boulder has devised a novel optical technique--a combination of structured illumination microscopy (SIM
2015, a team of researchers from the Stowers Institute for Medical Research and the University of Colorado Boulder combined two optical systems in a new way to get around the natural limits of optical microscopes.
something most medicines cannot do. The reprogrammed cells travel to the brain and produce tiny bubbles called exosomes that contain GDNF.
and technology to achieve"precision medicine, "said Shu Chien, a professor of bioengineering and medicine, director of the Institute of Engineering in Medicine at UC San diego,
and a corresponding author on the study.""While this proof of principle study demonstrates specific delivery of therapeutic agents to treat cardiovascular disease and bacterial infections,
One of the most critical biological and medical tools available today, it lies at the core of genome analysis. Reading the exact make-up of genes,
That means the materials aren't durable enough for consumer electronics or biomedical devices.""Metallic materials often exhibit high cycle fatigue,
which would enhance the effectiveness of medical interventions. The key breakthrough underlying this new technology came by chance."
Moreover, these DNA NANOSTRUCTURES provide new applications in molecular medicine, such as novel approaches in tackling cancer.
For molecular medicine, tiny DNA-based devices could be utilized not only in detecting single molecules but also in modulating cell signaling.
and the group has published just recently two research articles regarding DNA-based applications in biotechnology and molecular medicine.
Virologists at Texas Biomedical Research Institute in San antonio prepared the viral samples for testing. The system combines two small chips, a microfluidic chip for sample preparation and an optofluidic chip for optical detection.
According to the lead researcher, Professor Trevor Lithgow, from the newly launched Biomedicine Discovery Institute (BDI) at Monash University in Melbourne, Australia,
opening the way to direct applications for medical research"he said. Professor Lithgow and his team used a novel technology that enables the systematic expansion of the genetic codes of living organisms to include unnatural amino acids beyond the common twenty.
from the newly launched Biomedicine Discovery Institute (BDI) at Monash University. He started working on the process of how proteins
"We bring scientists from across all the biomedical disciplines together with mathematicians, chemists and others to make important discoveries that provide critical new information about how our bodies function.
The international effort needed to unlock this problem is a great example of the global nature of modern biomedical research.
Targeted modification of such proteins therefore plays a significant role in medical diagnostics and therapies.
The investigators demonstrated that two important steps of the lab in a needle approach accurately detected liver toxicity in preclinical models by measuring two genetic indicators of toxicity in AST and ALT.
"explained Stephen T. C. Wong, Ph d.,P. E.,Chair of the Department of Systems Medicine and Bioengineering at Houston Methodist Research Institute."
who is also a professor of radiology, neuroscience, pathology and laboratory medicine at Weill Cornell Medical College.
including cancer drug delivery and implantable biomedical devices. However the UT Austin team is thought to be one of the first to pursue the use of polydopamine as a flame retardant.
The hydrogel may be most useful for surgeries particularly for patients who take anticoagulant drugs to thin their blood."
This is important because surgical bleeding in patients taking heparin can be a serious problem. The use of batroxobin allows us to get around this problem
The substance used for medicine is produced by genetically modified bacteria and then purified, avoiding the risk of other contaminant toxins.
"We think SB50 has great potential to stop surgical bleeding, particularly in difficult cases in
of physical therapy and of neurological surgery at the School of medicine, has received a three-year, nearly $1. 9 million grant from the Defense Advanced Research Projects Agency (DARPA) to test a novel device his lab developed that would stimulate the nerves in the upper arm and forearm.
Wilson (Zach) Ray, MD, assistant professor of neurological surgery, both at the School of medicine; and Matthew Macewen, who will graduate with an MD/Phd in May 2015
particularly as applied to medicine and health, energy and environment, entrepreneurship and security. With 91 tenured/tenure-track and 40 additional full-time faculty, 1, 300 undergraduate students, more than 900 graduate students and more than 23
They presented their findings Aug 26 at the 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society in Milan, Italy.
says James Collins, the Termeer Professor of Medical Engineering and Science in MIT Department of Biological engineering and Institute of Medical Engineering and Science (IMES).
#Liquid crystals Detect Protein Fibers Associated with Development of Neurodegenerative Diseases Liquid crystals are familiar to most of us as the somewhat humdrum stuff used to make computer displays and TVS.
as detectors for the protein fibers implicated in the development of neurodegenerative diseases such as Alzheimer's.
"Amyloid fibrils are protein aggregates that are associated with the development of neurodegenerative diseases including Huntington's disease, Parkinson's, Alzheimer's,
this is the property that makes it useful for medical sonograms.""This could be a big advantage
The 3d printed pill dissolves in the same manner as other oral medicines. Being able to 3d print a tablet offers the potential to create bespoke drugs based on the specific needs of patients,
Previously, such personalised medicine would have been extremely expensive to produce, said Dr Alhnan. 3d printing works by creating an object layer by layer.
In the case of medicines printers are adapted to produce pharmaceutical compounds rather than polymers which are used more usually.
And dentists, for example, use 3d printers to create replica jaws and teeth as well as other dental implants s
or take medicines"."They will be tested to see how they overcome realistic scenarios, like navigating household clutter or picking things up for mobility-impaired residents.
Wi-fi cameras and sensors have also been installed on furniture, doors, medicine bottles, fridges, plugs and kettles inside the flat, dubbed the Personalised Assisted living facility.
and should be able to transform the way that'age'is used to make medical decisions.
Ph d.,Wyss Institute Core Faculty member and the Termeer Professor of Medical Engineering & Science and Professor of Biological engineering at MIT, is also a co-investigator
"Cas9 has emerged as a revolutionary tool allowing us to conquer new biomedical and industrial territory.
MURATA Yoji at the Kobe University Graduate school of Medicine Division of Molecular and Cellular Signaling, were the first to demonstrate the role of stomach cancer-associated protein tyrosine phosphatase (SAP)- 1 in the pathogenesis and prevention of Crohn's disease, ulcerative colitis,
Inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, are disorders of unknown etiology that are characterized often by abdominal pain, diarrhea, bloody stool, fever,
who qualify for the special Government-led medical assistance system for intractable diseases. Currently the administration of anti-inflammatory agents only provides palliative results,
'said lead author Dr Nicholas Turner, a Consultant Medical Oncologist at the Royal Marsden NHS Foundation Trust.
The study, published in Science Translational Medicine, looked at 55 patients with early-diagnosed breast cancer,
who had undergone all surgery followed by chemotherapy. The researchers took blood samples from these patients every six months for two years to look for circulating tumour (ct) DNA.
'We are moving into an era of personalised medicine for cancer patients. This test could help us stay a step ahead of cancer by monitoring the way it is changing
Regeneron is currently performing preclinical safety testing and may eventually conduct clinical trials if a safe clinical trial can be designed.
pregnant women and people with chronic medical conditions, who are believed to be at greater risk of influenza complications.
and the US government, aims at warzone use but the tech could also be applied to public quarantines, personalised medicine,
and Rao recognised that this sort of expensive military medicine touches only he 0. 01 per cent.
Cell-free production tech could be used to produce low-cost vaccines tremendous paradigm shift is definitely comingas well as personalised medicines.
and the US government, aims at warzone use but the tech could also be applied to public quarantines, personalised medicine,
and Rao recognised that this sort of expensive military medicine touches only he 0. 01 per cent.
Cell-free production tech could be used to produce low-cost vaccines tremendous paradigm shift is definitely comingas well as personalised medicines.
The research and preclinical trial results were published this month as an open access article in EBIOMEDICINE,
Preclinical studies with various cultured human cells as well as on rodents show that these new molecules are effective against cervical,
Unfortunately, the inclusion of platinum in the molecule causes serious side effects like neurotoxicity kidney damage, hearing loss, nausea and vomiting."
when a patient has an outwardly similar but infection-free syndrome called sterile inflammation, an intense, systemic inflammatory response to traumatic injuries, surgery,
said Purvesh Khatri, Ph d.,assistant professor of biomedical informatics research. Sepsis or sterile inflammation? In practice, distinguishing sepsis from sterile inflammation is a toss-up.
Khatri is the senior author of the new study, published May 13 in Science Translational Medicine, in
. a postdoctoral scholar now doing a residency in general surgery at Stanford. Numerous studies have been conducted to find differences in the activation levels of immune-response genes between infection-related inflammation and sterile inflammation.
600 patients in 27 different data sets containing medical information on diverse patient groups men and women, young and old,
following a surgery or injury, in inflammation-related gene activity over time, independent of the presence or absence of infection.
therefore time according to how soon a blood sample was drawn after the initial injury or surgery.
The study was funded by the Stanford Department of Surgery and by the National Library of Medicine and the National Institute of Allergy and Infectious diseases.
Daniel Moran, Ph d.,professor of biomedical engineering in the School of engineering & Applied science and of neurobiology, of physical therapy and of neurological surgery at Washington University School of medicine in St louis
Moran team includes Harold Burton, Ph d.,professor of neurobiology and Wilson (Zach) Ray, M d.,assistant professor of neurological surgery, both at the School of medicine;
#Uncovering Genetic Factors in Leukemia Northwestern Medicine scientists have discovered how a gene linked to leukemia functions,
. and Lora S. Lurie Professor in Medicine-Hematology/Oncology and Biochemistry and Molecular genetics, and a member of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
Now, in a paper published in the Journal of Experimental Medicine, they expanded on that research by studying the gene in depth.
The findings could have implications for the prevention of neurodegenerative diseases that are characterized by plaque buildup.
and professor in the department of Anesthesiology and Radiology at Stony Brook University School of medicine in New york told Bioscience Technology that it is too early to comment on humans,
and therefore overall waste clearance is diminished. his could have implications for prevention of certain neurodegenerative diseases. e speculate that
or postpone onset of neurodegenerative diseases such as Alzheimer, Benveniste told Bioscience Technology. Imaging testing in humans is needed still.
and to prevent neurodegenerative diseases
#Capturing Cell Growth in 3d Replicating how cancer and other cells interact in the body is somewhat difficult in the lab. Biologists generally culture one cell type in plastic plates,
In addition to the direct medical implications, the new study also shifts a fundamental principle of biochemistry known as allostery.
report researchers at University of California, San diego School of medicine in the current issue of JAMA Neurology.
Institute and a neurologist at VA Medical center, San diego. The findings are derived from postmortem analyses of 10 patients who participated in phase
Administering NGF directly into the brain a first for treating of an adult neurodegenerative disorder was done for two reasons.
who has been principal investigator for the trials from the beginning. his means that growth factors as a class consistently result in activation of dying cells in human neurodegenerative disorders. uszynski said the findings indicate NGF is extended safe over periods and that it merits continued
inhaled anesthetics like nitrous oxide and halothane have made modern surgery possible. Now, in experiments in mice, researchers at Johns Hopkins and elsewhere have added to evidence that certain so-called"volatile"anesthetics--commonly used during surgeries--may also possess powerful effects on the immune system that can combat viral and bacterial infections in the lung,
including influenza and pneumonia. A report on the experiments is published in the September 1 issue of the journal Anesthesiology.
The Johns Hopkins and University of Buffalo research team built its experiments on previous research showing that children with upper viral respiratory tract infections who were exposed to the anesthetic halothane during minor surgical procedures had significantly less respiratory symptoms
and a shorter duration of symptoms compared with children who did not receive halothane during surgeries.
To examine just how some inhaled anesthetic drugs affect viral and bacterial infections, Krishnan Chakravarthy, M d.,Ph d.,a faculty member at the Johns Hopkins Institute of Nanobiotechnology and a resident physician in the department of anesthesiology and critical
care medicine at Johns hopkins university School of medicine and Paul Knight, M d.,Ph d.,a professor of anesthesiology at the University of Buffalo School of medicine and Biomedical sciences, along with others
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