-H in cell lines, primary neuron cultures and zebrafish using molecular genetics, protein biochemistry and high speed imaging.
-H in cell lines, primary neuron cultures and zebrafish using molecular genetics, protein biochemistry and high speed imaging.
From River Besòs sediments, after three years'research, the researchers have obtained a stable bacterial culture
Previous work in this realm relied on"growing the cell cultures in a Petri dish, which tends to deform the structure,
"And, borrowing from previous cell culture work done by our group, our high-frequency ultrasound method detects changes within the stiffness of cells with high accuracy.
meaning that all the cells in the culture are quite similar to each other in the way they express their genetic information. reviously,
Now that they have a reliable human beige fat cell culture system, Kajimura said, his team will be able to use the system as a screening platform to identify
and amount of TMPRSS2 in these cancer cell cultures stood in exact correlation with the known level of pain each cancer causes. t was exactly
using them to measure activity in the larger culture population, which can include as many as a million cells. ecause we have all those electrodes,
and then compare the amount of activity being expressed by the culture to a target rate,
The optoclamp can be used to control cell cultures grown atop electrode arrays as well as in living animal models in
allowing experiments to focus stimulation on specific areas of the brain or brain cell cultures. The light signals now affect an entire culture
or brain region. e want to precisely control where photons are being sent to activate different cells, Newman said. ptogenetics allows genetic specification
Then scientists placed the cells into culture conditions containing certain cytokines and soon saw that their efforts were continued successful cells to divide as stem cells instead of undergoing differentiation into B-cells.
In a culture without these cytokines the cells differentiated into various immune cells. Team wanted to test
he CPM+LPCS that we have derived from human ipscs can be transferred from one medium to another for continuous culture
and smuggle cancer signals their neighbors New research in The FASEB Journal suggests that an in vitro co-culture system robustly quantifies the transfer of fluorescent proteins between cells
The article also touches upon the misogyny that possibly exists within the modern dating culture.
"but rather in the midst of reviving the dating culture by building something that is changing the world"and leading to"meaningful relationships."
"While reading the recent Vanity fair article about today's dating culture, we were saddened to see that the article didn't touch upon the positive experiences that the majority of our users encounter daily,
Turkey's journey towards a new startup culture While far from the levels of Greece, Spain,
"We have to establish a culture of food machine usage. Cooks are keen to do demonstrations
or not the new finding spells trouble for modern civilization it likely will help researchers understand how
and practice cultures across our health system increases the generalizability of our findings to other health care settings.
The researchers studied the squeezed B cells in culture and found that they could expand antigen-specific T cells at least as well as existing methods using antibody-coated beads.
but let them experience the hacker culture, and collaborate with really different thinkers of this world,
The Sony hack has displayed a lot about the failing of our modern, wired corporate culture. Like just how casual internal company HR employees treat email communication, for example.
A company that starts out with a closed paradigm and later chooses to open up will have a tough time rerouting company culture
and contributes weekly to art & culture magazine Beautiful/Decay. With online sales up 17%and physical retail down 11%,it no wonder retailers large and small are increasingly living online.
and a robust arts culture and one day we hope to be able to bring their work to our global audience of over 57 million members.
More importantly, deep fragmentation between language and cultures meant humans from different backgrounds were unable to effectively communicate with each other.
Wide adoption of a set of unicode ideograms helped people of different cultures to communicate with one another
Nevertheless with a population of 144 million people and a strong tech culture the country represents a lot of emerging market opportunity for Apple (and others.
Our culture is trained to think about a person with an unusual body or mind as weak Herr says.
a Dutch social psychologist who developed ways to measure a set of cultural dimensions for comparing cultures.
It shows that differences in culture affect the dynamics of social spreading processes in a measurable way.
whose cultures differ in how they value individualism versus collectivism, say Lang and co. What more,
Thanks to its privacy laws and discreet culture, the country is emerging as a hub for advanced security technology.
and almost immediately identifying dangerous bacteria at the bedside much faster than the days it normally takes to grow or"culture"the microbes in the laboratory from a patient's blood,
"We were able to demonstrate that we could make this scaffold and culture cells within it,
if it weren for the unique culture at UC San diego that fosters entrepreneurship. hat one of the reasons
"Could eventually replace animal models Modeling early heart development is difficult to achieve in a petri dish and tissue culture plates,
and neural progenitors. he idea is coated culture vessels with the polymer are arranged into arrays or factories each capable of supporting the production of billions of human pluripotent stem cells for applications in regenerative medicine and transplants.
and neural progenitors. he idea is coated culture vessels with the polymer are arranged into arrays or factories each capable of supporting the production of billions of human pluripotent stem cells for applications in regenerative medicine and transplants.
that we can culture the entire construct over prolonged periods of time, and that we can repopulate the vascular system and musculature.
At the same time, populations of muscle and vascular cells were being grown in culture. The research team then cultured the forelimb matrix in a bioreactor, within
After five days in culture, electrical stimulation was applied to the potential limb graft to further promote muscle formation, and after two weeks
and small genomes, may be the reason they can be grown in lab culture: they are stripped-down life forms with the barebones requirement of genes,
because some organisms detected widely in the environment fail to grow in culture like other bacteria.
though only 29 have representatives that will grow in culture. The new discovery allowed the team not only to define about a third of all bacterial phyla but, thanks to the nearly complete genomes
#New Single-use Harvesting Technology for High Cell Density Cultures Sartorius Stedim Biotech (SSB), a leading international supplier for the biopharmaceutical industry, has introduced Sartoclear Dynamics,
a clarification system featuring new single-use technology for harvesting mammalian cell cultures with high cell densities.
DE can be mixed directly into the cell culture fluid. This porous filter aid prevents blockage of the filters.
The ready-to-use clarification system enables harvesting of high cell density cultures up to 2, 000 liters 0
Could eventually replace animal models Modeling early heart development is difficult to achieve in a petri dish and tissue culture plates,
living in culture, these cells are not suitable for hair transplants, since they lost their ability to induce follicle formation.
seeded into a 3d scaffold and nourished with a culture gel full of nutrients to encourage growth.
but just 29 have species that will grow in laboratory cultures. The team has named now 20 the new phyla they identified after award-winning microbiologists
'Modeling early heart development is difficult to achieve in a petri dish and tissue culture plates,
s AI going to destroy civilization as we know it? It not just people on the street, Christian says. t also true for a lot of the people at the very places developing these technologies. hristian cites the example of Stuart Russell, a professor of computer science at the University of California, Berkeley,
and collaborative in ways that rivaled---if not beat--the work cultures of other great companies
a massive talent pool to explore for great culture and skill fit, says Jake Goldman,
5 Essential Keys to Leading a Remote Workforcetraditional companies foster company culture mainly through in-person activities.
and develop remote company cultures. Vadun, of Fireenginered, says the company has virtual book and walking clubs.
Origin Eight, a web and application development company with 25 remote workers, takes time to build culture.
And it takes leadership to further the culture, says CEO and founder Seth Viebrock. In-person meetings are still valuable,
says Emily Tetto, director of talent and culture. Scrapinghub, a data and information extraction company with 107 remote workers, focuses on motivation over productivity.
Company culture is vital to hiring and retaining workers. Switching management techniques to focus less on face time and more on goals and results would increase productivity at every company.
and Obama, promoted"vulgar culture, "committed fraud by pretending to be Communist party officials or agitated for separatist causes.
and colleague, Woodring E. Wright, M d.,Ph d.,professor of cell biology and internal medicine, found that 6-thio-2'-deoxyguanosine could stop the growth of cancer cells in culture and decrease the growth of tumors in mice.
and membership and professional societies. takeholders in clinical trials should foster a culture in which data sharing is expected the norm,
#Pall Acquires Innovative Acoustic Wave Separation Technology Pall obtained an exclusive license for acoustic wave separation (AWS), a disruptive technology from Flodesign Sonics for cell culture clarification for both
The technology will complement Pall's STAXTM depth filtration products to enable continuous clarification of cell culture, enabling integration of the bioreactor with downstream processing
When a cell culture passes through the flow channel, the cells are trapped at the nodes of the acoustic waves
"The AWS products will eliminate the reliance on centrifugation for cell culture clarification, and will provide a continuous feed stream for direct integration with the Biosmb platform.
Pall plans to introduce a single-use product line using AWS technology for the clarification of cell culture at both bench scale
"It works in a wide range of cancers both in culture and in human tumors developing in animal models,"explained Dr. Burris."
#Biopharma Demand Is Driving the Cell Culture Market The production of biologic therapies such as vaccines, blood factors,
and monoclonal antibodies is based on cell culturend the products that facilitate cell culture. According to Kalorama Information, these products,
The demand for cell culture and related products is not just rising, but accelerating, a phenomenon that is reflected in the timing of biopharmaceutical product launches:
The market for cell cultures is expected to grow rapidly alongside biopharmaceuticals and with significant evolution in culture technology.
Bacterial culture is the workhorse of the biotechnology industry. Animal cells are much more fragile than yeast and bacterial cells.
Animal cell culture is complicated more; thus, it is more expensive than traditional fermentation. The most widely used animal cells are Chinese hamster ovary (CHO) cells.
and thus are easier to grow in culture. CHO cells are epithelial cells that were introduced to science in the 1950s.
and grow well in culture. Cell Culture Media Trends The increasing use of mammalian cell lines,
including versatile and uniquely capable stem cells, in upstream bioprocessing has imposed specific demands on cell cultures:
namely, better-defined media. The rising stakes and production levels of companies active in biopharmaceuticals have dictated improved reproducibility or consistency in product;
and the use of culture product more amenable to downstream processing or purification. Media can be organized into three broad types:
The biopharmaceutical industry shift away from animal-derived culture products is expected to continue, particularly given the ascension of mammalian cell lines in biopharmaceutical production.
Working and Master Cell Banks Once a biopharmaceutical company obtains a beginning cell bank from a cell culture collection,
Shifts in Productive Capacity Cell culture production is growing faster in the Asia Pacific region than any place else in the world.
New technologies used in cell culture production, in particular single-use disposable production systems, are dramatically lowering building costs of biomanufacturing plants.
Market Drivers An important driver of the cell culture market is the production of seasonal influenza vaccines,
However, this labor-intensive approach to vaccine development is currently being replaced by cell-culture systems.
Prefluce, the first cell culture-based vaccine, received European approval in March 2011 and was available for the 2011012 influenza season in the 13 participating European union countries.
which is the first U s.-licensed (trivalent inactivated) influenza vaccine manufactured using cell culture technology.
Stem cell research will also add to the robust growth of the cell culture market. The growing use
the word changed from blue to red. a plastic dish imprinted with BMP-2 proteins that stimulate bone growth to control the direction of tissue growth. sodium ampicillin printed on a bacterial culture printed to test the effectiveness of a topographical distribution of the antibiotic
Just last month at the International Society for Stem Cell Research conference in Stockholm, scientists reported updated methods to more reproducibly culture organoids with better architecture.
Rather, the clock is a visual metaphor to warn the public about how close the world is to a potentially civilization-ending catastrophe.
and smooth muscles cells and having the cells culture for a period of up to two weeks in a static bioreactor.
"In the past, people have used impedance spectroscopy for cell cultures or relatively simple measurements in tissue. What makes this unique is extending that to detect
and destroying norovirus Hansman's research team recently discovered that a"nanobody"called Nano-85 was able to bind to intact norovirus-like particles (VLPS) in culture.
Culture, Sports, Science and Technology (MEXT) E
#Leti Demos New Process to Fabricate High-brightness Micro-LED Arrays for Next-gen Head-mounted and Head up displays:
"We estimate yields on the order of grams per liter from batch cultures under optimized conditions,
or culture, to grow and divide. After one week, their numbers had expanded by an estimated 5, 000 to 10,000 times.
The researchers studied the squeezed B cells in culture and found that they could expand antigen-specific T cells at least as well as existing methods using antibody-coated beads.
that we can culture the entire construct over prolonged periods of time, and that we can repopulate the vascular system and musculature."
At the same time, populations of muscle and vascular cells were being grown in culture. The research team then cultured the forelimb matrix in a bioreactor, within
After five days in culture electrical stimulation was applied to the potential limb graft to further promote muscle formation,
"We were able to demonstrate that we could make this scaffold and culture cells within it,
called Body-on-a-Chip (BOC), replacing the 2d cell culture conventionally used for drugs testing with a multi-tissue device that better mimics real-life conditions in the body, by combining several organ
-specific 3d cultures into a single chip. Researchers then created a prototype BOC to assess the toxicological risk of new candidate compounds
The problem with this is that 2d cell cultures can lose their functionality within about 48 hours, in the case of liver cells for instance
Scientists on the BOC project loaded 3d cell cultures (spheroid micro-tissues representative of human organs such as the liver or heart) into compartments connected by tiny tubes,
This metabolite toxicity can't be detected by classic 2d culture. Commercial multi-tissue device could be ready in three years A device comprising rat cells,
and they developed early prototypes with six and eight compartments that the project demonstrated could be extended to human cell cultures. arly-stage backing from the EU has helped really us develop a robust prototype
According to their paper, their 3-D organ outperforms existing 2-D cultures and can produce activated B cells up to 100 times faster.
"We estimate yields on the order of grams per liter from batch cultures under optimized conditions,
as guinea pigsvicious vaccine culture war now being waged against informed, intelligent Americans who seek to protect their children from deadly side effects131 Ways for an Infant to Die:
and a host of other pathogens in cell cultures. If the compound behaves similarly in people
A RIKEN team has succeeded in developing a culture method that allows human embryonic stem cells to be efficiently
After a few weeks in culture these cells would spontaneously self-assemble into three-dimensional retinal tissue.
refined and improved this culture technique through precisely timed treatment with a regulatory protein called BMP4.
and help contribute to retinal tissue growth in the culture dish. This degree of cellular organization is the closest scientists have yet come to building self-growing retinal tissue from stem cells. ur results are consistent with the current view that the retinal pigment epithelium
and neural retina are capable of ate transition says Eiraku. y examining retinal formation in culture,
and his colleagues could one day be used to culture tissue that can be transplanted into a human retina damaged by conditions such as macular degeneration and retinitis pigmentosa,
We recently reported the ability of human embryonic stem cells (hescs) to self-organize stratified NR using a three-dimensional culture technique.
First, we developed a culture method for selective NR differentiation by timed MP4 treatment. We then found that inhibiting GSK3
-or neuro-stimulating drugs. e were able to demonstrate that we could make this scaffold and culture cells within it,
a process known as staple isotope labeling of amino acids in cell cultures and live mice. When examining the nerve cells,
"We've failed so far to find drugs to treat diarrhea using cell culture models
"commented Karin Roesch of MIT Media Lab's Camera Culture Group.""In traditional approaches, where the image of a fixation target passes through only one point of the pupil
a collaborative program between the LV Prasad Eye Institute in Hyderabad and the MIT Media Lab Camera Culture group,
3-D cell cultures and engineered tissue constructs; as well as imaging 3-D dynamics in microfluidics and flow-cell cytometry systems.
Each rainbow-colored bar is the fluorescent spectrum from a discrete point in a cell culture.
the researchers used cell cultures and mice to study the effects of sialylated Fc regions binding to B cells.
Shaped like little smiling fish-a symbol of luck in Cambodian culture-these inexpensive iron lumps are about 7. 5 centimetres long
and monitoring growth of tissue cultures, and networks for 3d electronic systems that can bend and shape themselves to the organs of the human body.
and motion in intact tissues 3d cell cultures and engineered tissue constructs as well as imaging 3d dynamics in microfluidics
They performed infection trials in a large number of cell cultures at different temperature levels. While pathogenic bunyaviruses can multiply at temperatures that include the human body temperature,
Culture, Sports, Science and Technology (MEXT) E
#Scientists discover a protein that silences the biological clock The ticking of the biological clock drives fluctuations in gene activity
and almost immediately identifying dangerous bacteria at the bedside--much faster than the days it normally takes to grow or"culture"the microbes in the laboratory from a patient's blood,
According to their paper, their 3-D organ outperforms existing 2-D cultures and can produce activated B cells up to 100 times faster.
and forming connections between them in vitro, in a single culture vessel, for the first time.""We have developed a human pluripotent stem cell (hpsc)- based system for producing connections between neurons from two brain regions,
which aims to foster change in operational culture at the school level. Its materials include t-shirts
"We estimate yields on the order of grams per liter from batch cultures under optimized conditions,
and activate immune cells in a two-week culture. Immune cells are extracted from lymph nodes which have been exposed to growing melanoma in the patient's body.
what impact longer culture periods have on embryos and genetic abnormalities and requires further investigation. Researchers say future studies should also focus on the zygote as a potential source of noninvasive biomarkers that can prospectively predict chromosomal status
and avoid potential detriment (s) of prolonged embryo culture r
#Scientists develop free, online genetic research tool"This work actually started mainly because of the demand of MU scientists,
I see gaming as an important part of modern culture. I think people are interested increasingly in VR worlds and communicating with virtual characters.
function, and motion in intact tissues, 3d cell cultures, and engineered tissue constructs, as well as imaging 3d dynamics in microfluidics,
and gel density and optimizing the culture matrix and media to make this work with human muscle cellssaid Madden.
with global production of about 650 million tonnes and consumption in a variety of breads across different countries and cultures. rowing global demand for wheat requires ongoing genetic improvement to adapt to changing environmental conditions,
-or neuro-stimulating drugs. e were able to demonstrate that we could make this scaffold and culture cells within it,
OSU recently agreed to a non-exclusive license for the patented Ropy 352 technology to a global market leader for dairy starter cultures.
According to their paper, their 3-D organ outperforms existing 2-D cultures and can produce activated B cells up to 100 times faster.
and forming connections between them in vitro, in a single culture vessel, for the first time. e have developed a human pluripotent stem cell (hpsc)- based system for producing connections between neurons from two brain regions,
you can kill the great majority of cells within a culture, he says. The expressed toxins are designed to disrupt different cellular processes,
Could eventually replace animal models Modeling early heart development is difficult to achieve in a petri dish and tissue culture plates,
Ten MSC sheets were created from a total cell number of 1×108 MSCS using temperature-responsive culture dishes.
and thus to the reduction in blood pressure. fter we had found clues in cell culture experiments that a certain docking site for ATP,
Minister of state for culture and the digital economy Ed Vaizey said: This report will be instrumental in driving savings
For Blair Garrou, cofounder and managing director of the Mercury Fund in Houston and a mentor to Surge companies, Surge shift in approach reflects the culture of its biggest customers:
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