*and ion concentration--critical markers for many disorders--rely on various nanosensors that are probed using light at optical frequencies.
and are just tens of nanometers (billionths of a meter) thick. See animation. Between the disks is a spacer layer of hydrogel,
Scanning the sample with a range of frequencies quickly identifies the current shape of the nanoprobes,
and might conceivably be made smaller than 100 nanometers in diameter. That would open up many additional biomedical applications.
Shape-changing magnetic assemblies as high-sensitivity NMR-readable nanoprobes. Nature, Published online March 16, 2015. doi:
#Breakthrough in DNA Science Opens the Way for Practical Nanomachines with Moving Parts The latest DNA nanodevices created at the Technische Universitaet Muenchen (TUM)- including a robot with movable arms,
They demonstrate a breakthrough in the science of using DNA as a programmable building material for nanometer scale structures and machines.
This not only opens the way for practical nanomachines with moving parts but also offers a toolkit that makes it easier to program their self-assembly.
as designed, with subnanometer precision. Yet all those advances employed"base-pairing"to determine how individual strands
"To enable a wider range of DNA nanomachines with moving parts and potentially useful capabilities,
To create a dynamic DNA nanomachine, the researchers begin by programming the self-assembly of 3d building blocks that are shaped to fit together.
"The team produced a series of DNA devices-ranging from micrometer-scale filaments that might prefigure technological"flagella"to nanoscale machines with moving parts-to demonstrate the possibilities
For example, transmission electron micrographs of a three-dimensional, nanoscale humanoid robot confirm that the pieces fit together exactly as designed.
Another method for switching a DNA nanodevice between its different structural states-by simply raising
we basically now have a way not just to build nanomachines, but also to power them.""
""A snap"-like child's play There is yet another dimension to the flexibility gained by adding shape-complementary components and weak bonding to the DNA NANOTECHNOLOGY toolkit.
#Breakthrough, Low-cost Method to Build DNA NANOTUBES Block By Block Researchers at Mcgill University have developed a new,
low-cost method to build DNA NANOTUBES block by block a breakthrough that could help pave the way for scaffolds made from DNA strands to be used in applications such as optical and electronic devices or smart drug-delivery systems.
have constructed previously nanotubes using a method that relies on spontaneous assembly of DNA in solution.
we can now build long nanotubes block by block, said Amani Hariri, a Phd student in Mcgill Department of chemistry and lead author of the study. y using a fluorescence microscope we can further visualize the formation of the tubes at each stage of assembly,
which enables scientists to peer into the nanoworld by turning the fluorescence of individual molecules on and off.
The custom-built assembly technique developed through this collaboration ives us the ability to monitor the nanotubes as wee building them,
who holds the Canada Research Chair in DNA Nanoscience. The resulting esigner nanotubes she adds,
promise to be far cheaper to produce on a large scale than those created with so-called DNA origami,
another innovative technique for using DNA as a nanoscale construction material. Funding for the research was provided by the Natural sciences and Engineering Research Council of Canada, the Canada Foundation for Innovation, Nanoquébec, the Canadian Institutes of Health Research and the Fonds de recherché du Québec Nature
#Electroluminescence with Phosphor Nanoparticles Holds Promise for Modern Lighting Light-emitting diodes (LEDS) are the modern lighting devices used in lamps, signals, signs or displays.
Special nanoparticles, so-called phosphors, are excited in an electric field to emit light. Researchers at the INM Leibniz Institute for New Materials have developed now a new method that enables electroluminescence on large
On application of an AC voltage, light is emitted from the electroluminescent layer. e embed luminous particles in the form of functionalized zinc sulphide nanoparticles as phosphors into the binder layer,
The researchers are currently working on further functionalization of the phosphor nanoparticles. ur goal is to generate white light by means of an altered doping
Nanocomposite Technology, Interface Materials, and Bio Interfaces. Source: http://www. inm-gmbh. de e
#Cerium-Based Material Made into Nanometer-Sized Particles to Produce Key Ingredient for Nylon Production The Critical Materials Institute,
a U s. Department of energy Innovation Hub led by the Ames Labratory, has created a new chemical process that makes use of the widely available rare-earth metal cerium to improve the manufacture of nylon.
The process uses a cerium-based material made into nanometer-sized particles with a palladium catalyst to produce cyclohexanone, a key ingredient in the production of nylon.
provider of the 3dna nanotechnology platform, reported today it has achieved specific immunodepletion of problematic Myo/Nog cells implicated in posterior capsular opacification (PCO), a clouding of the eye lens
when the mab was used as a targeting device on Genisphere's 3dna nanocarrier loaded with doxorubicin.
and 3dna nanocarriers can deliver a variety of drug cargoes, we can easily generate targeted drugs for many of these indications."
"Genisphere's partnership model for development of nanotherapeutics has set the path forward for clinical testing and future commercialization of these and other candidates. t
The thickness of the silicon films ranges from 20 to 200 nanometers for creating different colors.
For reference, 100 nanometers is about 1/1000 of the thickness of a single sheet of paper.
One nanometer is about two atomic layers of silicon. The silicon color coating process can be applied on almost any material surface.
In future, Tillmann and Wagner are planning to use the surface-bound Cl3si anchor groups to produce three dimensional nanonetworks out of Si20 units.
"Spatially strictly limited silicon nanoparticles display fundamentally different properties to conventional silicon wafers, "explains Matthias Wagner.
thus opens up the possibility of studying the fundamental electronic properties of cage-like Si nanoparticles compared to crystalline semiconductor silicon.
www. N1technologies. com and www. Tungstenglass. com N1 Technologies Inc. is a Global leader in Nanotechnology research and Development.
enabling researchers to observe internal features such as nanoscale cracks and voids that ultimately lead to deformation and failure at the macroscale.
The University of Manchester in Manchester, UK has performed 3d in situ imaging of crack growth using Xradia Ultra Load Stage in nanoindentation mode to understand how cracks grow in dentin, the nanocomposite that forms the bulk of teeth.
"In situ nanomechanical testing in the Xradia Ultra X-ray microscope has enabled us to link the nanoscale 3d structure of a material directly to its performance.
and quantifying 3d nanostructures under load. This is a completely unique capability that offers new opportunities to connect small scale evolution processes with those observed in micron scale XRM and bulk material testing."
offering new capabilities to observe internal processes at nanoscale resolution. Until now, electron microscopy techniques provided resolution down to the nanometer range
but are limited to surface imaging (SEM) or required extremely thin samples whose mechanical behavior will be affected strongly by surface effects (TEM).
In combination with innovative quantitative approaches and numerical simulations, they were also able to define the genome architecture at the nanoscale.
#Innovative Fabrication Technique for Hybrid Nanostructure Supercapacitor Electrode Offsetting this promise is the fact that,
Now two researchers from the S n. Bose National Centre for Basic Sciences, India, have developed a novel supercapacitor electrode based on a hybrid nanostructure made from a hybrid nickel oxide-iron oxide
from AIP Publishing, the researchers report the fabrication technique of the hybrid nanostructure electrode. They also demonstrate its superior performance compared to existing, non-hybrid supercapacitor electrodes.
National Centre for Basic Sciences, mixed nickel oxide and iron oxide as a hybrid material and fabricated the novel core/shell nanostructure electrode."
In Singh's experiment, the core/shell hybrid nanostructure was fabricated through a two-step method. Using a standard electro-deposition technique,
the researchers grew arrays of iron-nickel nanowires inside the pores of anodized alumina oxide templates,
then dissolved the templates to obtain the bare hybrid nanowires. After that, the researchers exposed the nanowires in an oxygen environment at high temperature (450 degreescelsius) for a short time,
eventually developing a highly porous iron oxide-nickel oxide hybrid shell around the iron-nickel core."
"The advantage of this core/shell hybrid nanostructure is that the highly porous shell nanolayer provides a very large surface area for redox reactions
and iron/iron oxide core/shell nanostructure electrodes, the hybrid material electrode demonstrated higher capacitance,
"The remarkable electrochemical performances and material properties suggest that the iron oxide-nickel oxide hybrid core/shell nanostructure could be a reliable and promising candidate for fabricating the next generation lightweight, low-cost
#Real-time Nanoscale Images of Lithium Dendrite Structures That Degrade Batteries Scientists at the Department of energy Oak ridge National Laboratory have captured the first real-time nanoscale images of lithium dendrite structures known to degrade lithium
ORNL electron microscopy captured the first real-time nanoscale images of the nucleation and growth of lithium dendrite structures known to degrade lithium-ion batteries.
and applying voltage to the cell allowed the researchers to watch as lithium depositshich start as a nanometer-size seedrew into dendritic structures. t gives us a nanoscopic view of how dendrites nucleate and grow,
and nanoscopic level to look at the structural and chemical evolution that happening in the cellshen you can truly address those issues that come up.
Solid electrolyte Interphase Formation and Preferential Growth of Lithium Metal Nanoclusters. Coauthors are Robert Sacci, Jennifer Black, Nina Balke, Nancy Dudney, Karren More and Raymond Unocic.
The nanotechnology engineered into the organic oil blend is the key to its ability to transfer heat,
The Organic Bio-Based Motor oil patent describes the assembly process for blending Nanotubes and various highly viscous all natural plant oils to form Nanosave N1-Organic.
http//www. nanosave. blogspot. com N1 Technologies Inc. is a Global leader in Nanotechnology research and Development.
#Canatu Announce Multitouch, Button-Free Automotive Panels with Carbon nanobud Films Canatu, a leading manufacturer of transparent conductive films, has in partnership with Schuster Group
Canatu CNB#(Carbon nanobud) In-Mold Film with its unique stretch properties provides a clear path to the eventual replacement of mechanical controls with 3d touch sensors.
Schuster Group is keen to utilize Canatu proprietary CNB#(Carbon nanobuds) In-Mold Film in their latest next generation product design.
Portions of this work were carried out in the Penn State Nanofabrication Facility, a node of the NSF-funded National Nanotechnology Infrastructure Network s
which measures the interaction of photons with an activated surface using nanostructures in order to do chemical and biological sensing.
The method produces measurements much more reliably. t Optokey wee able to mass produce this nanoplasmonic resonator on a wafer scale,
which are nanocrystals with peculiar properties, and began exploring their use in biology. That led to further investigations into nanomaterials.
One accomplishment was a so-called molecular ruler made of gold nanoparticles tethered to DNA strands, which, using plasmon resonance,
was capable of measuring protein-DNA interactions. Ultimately Chen and his group developed about 20 patents involving hybrid bionanomaterials.
The key discovery that led to the formation of Optokey was the development of the nanoplasmonic resonators to dramatically improve the signal and reliability of Raman spectroscopy.
#Packaging Cancer drug into Nanoparticles Double Tumor Destroying Efficacy Researchers have packaged a widely used cancer drug into nanoparticles,
forming a water-soluble nanoparticle with the drug hidden in its core. These nanoparticles are highly soluble in blood
and are the perfect size to penetrate and accumulate in tumors where they take advantage of a tumor's acidic environment."
creating an electrode made of nanoparticles with a solid shell, and a olkinside that can change size again and again without affecting the shell.
The use of nanoparticles with an aluminum yolk and a titanium dioxide shell has proven to be he high-rate champion among high-capacity anodes
That where the idea of using confined aluminum in the form of a yolk-shell nanoparticle came in.
In the nanotechnology business there is a big difference between what are called ore-shelland olk-shellnanoparticles.
which are about 50 nanometers in diameter, naturally have oxidized an layer of alumina (Al2o3). e needed to get rid of it,
which reacts with titanium oxysulfate to form a solid shell of titanium hydroxide with a thickness of 3 to 4 nanometers.
#Dresden Nanoscope Combines Microscopy and Ultra-Fast Spectroscopy for Precise Filming of Dynamic Processes To gain even deeper insights into the smallest of worlds,
This makes highly precise filming of dynamic processes at the nanometer scale possible. The results were published recently in the research journal Scientific Reports (DOI:
On the one hand, this is due to the fact that such processes take place on a scale of a millionth of a millimeter (nanometer)
Time increments from a few quadrillionths of a second (femtoseconds) up to the second range can be selected for individual images. his makes our nanoscope suitable for viewing ultra-fast physical processes as well as for biological process,
Combining two methods guarantees high spatial and temporal resolutionthe nanoscope is based on the further development of near-field microscopy
one can achieve a spatial resolution in the order of the near-field magnitude, that is, in the nanometer range.
the teams led by the two Dresden physicists have managed to combine all the advantages of both methods in their nanoscope. e have developed software with a special demodulation technology with whichn addition to the outstanding resolution of near-field
The clever electronic method enables the nanoscope to exclusively record only the changes actually occurring in the sample's properties due to the excitation.
Although other research groups have reported only recently good temporal resolution with their nanoscopes they could not,
Universal in every respectith our nanoscope considerable wavelength coverage, dynamic processes can be studied with the best suited wavelengths for the specific process under study.
The Dresden nanoscope is universally adaptable to respective scientific questions. The probe pulse wavelengths can,
and nanospectroscopy, is illustrated in Nature Nanotechnology. ur microscope offers a noninvasive rapid method to explore materials simultaneously for their chemical and physical properties,
The originality of the instrument and technique lies in its ability to provide information about a material chemical composition in the broad infrared spectrum of the chemical composition while showing the morphology of a material interior and exterior with nanoscale a billionth of a meter resolution.
Passian This unique microscope will enable users to analyze samples ranging from engineered nanostructures and nanoparticles to naturally occurring plant cells, biological polymers and tissues.
The first application in which this microscope was deployed in the DOE Bioenergy Science Center was for analyzing plant cell walls,
The cell wall of a plant is layered a nanostructure made up of biopolymers such as cellulose. Researchers are looking to convert these biopolymers to free the functional sugars and discharge energy.
An urgent need exists for new platforms that can tackle the challenges of subsurface and chemical characterization at the nanometer scale.
including work at synchrotron light sources and nanoscience research centers. OE light sources offer a rich environment for tackling wonderful math problems whose solutions can make a major impact on fast moving sciencesays Sethian. ombining Zwart insight into the problem with Donatelli
Cornell researchers examined these special nylon sheets replete with applied nanoscale iron oxide particles to see
The study evaluated the nanoparticle treatment uniformity and particle retention of the nylon membranes as they were processed
and chemically grafted nanomembranes loaded with iron oxide nanoparticles, in the Journal of Applied Polymer Science, July 14.
Adhering nanoparticles of iron oxide to nylon fiber is done in three ways: electrospraying, which facilitates uniform nanoparticle placement in the fibers;
layer-by-layer assembly, where particles are coated on the fiber electrostatically; or chemical bonding. or the membrane, it important to evaluate particle retention and stability,
Trejo explained. ou would want the nanoparticles to stay on the Nylon 6 membranes so the material can have function throughout the life use.
Cornell Nanobiotechnology Center and the Cornell Nutrient Analysis Laboratory supported this research. Can nanofiber save your life?
Researchers in professor Margaret Frey lab create fibers hundreds of times thinner than a human hair that can capture toxic chemicals and pathogens.
Frey and her colleagues are replacing that cost by making the devices with nanofibers from plastics,
Using nanofibers, processes done in a medical testing lab for example, purifying samples, mixing ingredients, capturing bacteria can be done with material about the size of a deck of cards.
Frey and her students have encapsulated pesticides into biodegradable nanofibers. This keeps them intact until needed
these nanofibers just might save a life, she said o
#Scientists Map 3d Atomic Structure of Brain Signaling Scientists have revealed never-before-seen details of how our brain sends rapid-fire messages between its cells.
#Researchers Apply Nanopore Gene Sequencing to Proteins University of Pennsylvania researchers have made strides toward a new method of gene sequencing a strand of DNA bases are read as they are threaded through a nanoscopic hole.
The Penn team technique stems from Drndic work on nanopore gene sequencing, which aims to distinguish the bases in a strand of DNA by the different percent of the aperture they each block as they pass through a nanoscopic pore.
Different silhouettes allow different amounts of an ionic liquid to pass through. The change in ion flow is measured by electronics surrounding the pore;
Drndic and her colleagues have experimented with applying the technique to other biological molecules and nanoscale structures.
Using the Drndic group silicon nitride nanopores which can be drilled to custom diameters, the research team set out to test their technique on GCN4-p1,
#MRI SCANNERS can Non-Invasively Steer Cells with Nanoparticles to Tumour Sites Magnetic resonance imaging (MRI SCANNERS have been used since the 1980s to take detailed images inside the body-helping doctors to make a medical diagnosis
which have been injected with tiny super-paramagnetic iron oxide nanoparticles (SPIOS), to both primary and secondary tumour sites within the body.
The combined effect of those patterns leads to final images with 62-nanometer resolution--better than standard SIM and a threefold improvement over the limits imposed by the wavelength of light."
Betzig's team also reports in the Science paper that they can boost the spatial resolution of SIM to 84 nanometers by imaging with a commercially available microscope objective with an ultra-high numerical aperture.
#Researchers Develop New Microscopic Imaging Techniques to help Advance Next-Generation Nanotechnology The research focuses on leveraging powerful tabletop microscopes equipped with coherent beams of extreme-ultraviolet (EUV) light.
more energy-efficient nanocircuit designs. etter imaging techniques are critical for all areas of science and advanced technology,
Boulder. abletop microscopes are needed for iterative design and optimization across a broad range of nanoscience and nanotechnology applications,
Although 10 nanometer (nm) spatial resolution was demonstrated, 25 nm is typical nowhere near the wavelength limit, according to the research team.
The team deep-ultraviolet and EUV laser-like source technology could be used for defect detection or other nanometrology applications either as a stand-alone solution or as an inline tool.
The EUV microscope could also provide high-contrast, low-damage, full-field, real-time imaging of functioning circuits and nanosystems,
among other fabrication application usages. any industries that harness nanotechnologies can benefit from better microscopes for iterative and smart designs,
Senior Science Director of Nanomanufacturing Materials and Processes at SRC. he resolution will only continue to improve as the illumination wavelengths decrease. w
A research group led by Tetsushi Taguchi, a MANA Scientist at the Biomaterials Unit, International Center for Materials Nanoarchitectonics (MANA),
Amorphous Nanoparticles from Wide Material Range Before Ibuprofen can relieve your headache, it has to dissolve in your bloodstream.
Researchers from Harvard John A. Paulson School of engineering and Applied science (SEAS) have developed a new system that can produce stable, amorphous nanoparticles in large quantities that dissolve quickly.
But that not All the system is so effective that it can produce amorphous nanoparticles from a wide range of materials,
These unstructured, inorganic nanoparticles have different electronic, magnetic and optical properties from their crystalized counterparts, which could lead to applications in fields ranging from materials engineering to optics.
Mallinckrodt Professor of Physics and Applied Physics and an associate faculty member of the Wyss Institute for Biologically Inspired Engineering at Harvard, describes the research in a paper published today in Science. his is a surprisingly simple way to make amorphous nanoparticles from almost any material,
The droplets are dried completely between one to three microseconds from the time they are sprayed, leaving behind the amorphous nanoparticle.
At first, the amorphous structure of the nanoparticles was said perplexing Esther Amstad, a former postdoctoral fellow in Weitzlab and current assistant professor at EPFL in Switzerland.
These factors prevent crystallization in nanoparticles, even in materials that are highly prone to crystallization, such as table salt.
The amorphous nanoparticles are exceptionally stable against crystallization lasting at least seven months at room temperature. The next step, Amstad said,
is to characterize the properties of these new inorganic amorphous nanoparticles and explore potential applications. his system offers exceptionally good control over the composition,
#Inner Space of Carbon nanotubes Could act as a Template for Synthesis of Linear-Chain Nanodiamonds The inner space of carbon nanotubes can act as a template for the synthesis of nanodiamond-like carbon chains.
this templated polymerization approach paves the way for the design of novel one-dimensional nanomaterials. Nanosized materials such as nanowires offer unique properties that are completely distinct from those of the bulk materials.
However, one-dimensional nanostructures are difficult to synthesize. In an international cooperation Hisanori Shinohara from Nagoya University in Japan and his colleagues have developed a method that uses carbon nanotubes as a reaction vessel for the templated polymerization of linear-chain nanomaterials.
The idea was that during polymerization, the small precursor molecules would naturally adopt the one-dimensional structure of the tubes
only if their inner diameter is small enough. Larger diameters would offer too much space so that the polymerization could terminate
Shinohara and his colleagues were able to synthesize a one-dimensional nanodiamond polymeric structure by a relatively simple annealing technique.
This molecule was brominated at either side so that, upon addition of iron nanoparticles, the bromine would be abstracted and a diradical formed.
#Researchers Demonstrate Breakthrough Method for Getting Nanoparticles to Self-Assemble The medium is the message.
An innovative method they have demonstrated now for getting nanoparticles to self-assemble focuses on the medium in
This approach is an elegant alternative to present methods that require nanoparticles to be coated with light-sensitive molecules;
uncoated nanoparticles into a light-sensitive medium would be simpler, and the resulting system more efficient and durable than existing ones.
The nanoparticles then react to the change in acidity in their environment: It is this reaction that causes the particles to aggregate in the dark
This means that any nanoparticles that respond to acid a much larger group than those that respond to light can now potentially be manipulated into self-assembly.
By using light a favored means of generating nanoparticle self-assembly to control the reaction,
when and where the nanoparticles will aggregate. And since nanoparticles tend to have different properties
if they are floating freely or clustered together, the possibilities for creating new applications are nearly limitless.
For one, the particles do not seem to degrade over time a problem that plagues the coated nanoparticles. e ran one hundred cycles of writing
and rewriting with the nanoparticles in a gel-like medium what we call reversible information storage
although we used gold nanoparticles for our experiments, theoretically one could even use sand, as long as it was sensitive to changes in acidity.
In addition to durable ewritable paper, Klajn suggests that future applications of this method might include removing pollutants from water certain nanoparticles can aggregate around contaminants
#Nanoscientists Convert Sunlight into Liquid fuel Using Nature and Technology Imagine creating artificial plants that make gasoline
By combining nanoscience and biology, researchers led by scientists at University of California, Berkeley, have taken a big step in that direction.
Peidong Yang, a professor of chemistry at Berkeley and co-director of the school's Kavli Energy Nanosciences Institute, leads a team that has created an artificial leaf that produces methane
the primary component of natural gas, using a combination of semiconducting nanowires and bacteria. The research, detailed in the online edition of Proceedings of the National Academy of Sciences in August, builds on a similar hybrid system, also recently devised by Yang and his colleagues,
#Microfluidics Technology-Based Lab-on-a-chip Device Could Reduce Cost of Sophisticated Tests for Diseases Rutgers engineers have developed a breakthrough device that can significantly reduce the cost of sophisticated lab tests for medical disorders
#Translational Grant for Interaction Study of Laser radiation with Circulating Tumor Cells and Melanin Nanoparticles University of Arkansas for Medical sciences (UAMS) researcher Vladimir Zharov, Ph d.,D. Sc.
Zharov is director of the Arkansas Nanomedicine Center at the UAMS Winthrop P. Rockefeller Cancer Institute and a professor in the UAMS College of Medicine Department of Otolarynology-Head and Neck Surgery.
and superficial veins and can heat the natural melanin nanoparticles in melanoma circulating tumor cells (CTCS).
The thermal expansion of these nanoparticles generates sound that can be detected with an ultrasound transducer attached to the skin.
This can improve the detection of CTCS by 1000-fold. he goal of this translational research grant is for patients to benefit from the knowledge obtained during our study of the interaction of laser radiation with circulating tumor cells and nanoparticles
Zharov said. any years ago we discovered that laser-induced high local temperature can evaporate liquid surrounding light-absorbing nanoparticles
and thus create vapor nanobubbles, Zharov said. Fast expansion and collapse of these nanobubbles significantly increases the sound10-50 fold
and mechanically kills CTCS so that it requires just a few laser pulses or even a single pulse without harmful effects on normal cells.
Natural melanin nanoparticles will be used as biomarkers to diagnose and as targets for therapy. Because not all melanoma cells highly express melanin
laser and nanotechnological methods to increase diagnostic and therapeutic efficiency. The researchers also discovered that many standard medical procedures especially vigorous manipulation of the tumor,
and then eradicate the CTCS by well-timed therapy including nanobubble-based treatment. A similar approach can be used to monitor the effectiveness of the different types of treatment for cancer by counting the CTCS before, during and after therapy.
Zharov team has demonstrated already that laser-induced nanobubbles significantly decrease the level of CTCS, leading to a decrease in the chances of cancer spreading to other organs. urther study could determine
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