#Nanospheres shield chemo drugs, safely release high doses in response to tumor secretions Scientists have designed nanoparticles that release drugs in the presence of a class of proteins that enable cancers to metastasize.
and build that into a nanoscale carrier that can seek out a tumor and deliver a payload of drug,
In mice treated with the nanoparticles coated with peptides that are impervious to MMPS or given saline,
Callmann holds a fellowship through the Cancer Researchers in Nanotechnology Program at UC San diego. The National Institute of Biomedical Imaging
#Nanoparticles used to prevent inflammatory acne through slow-released nitric oxide GW researcher and dermatologist, Adam Friedman, M d,
and prevent acne through nanotechnology. This research, published in the Journal of Investigative Dermatology, identified that the nanoparticles were effective at killing Proprionobacterium acnes,
the gram positive bacteria associated with acne, and even more importantly, they inhibited the damaging inflammation that result in the large,
Utilizing an established nanotechnology capable of generating and releasing nitric oxide over time, Friedman and his research team at the Albert Einstein College of Medicine
which the nanoparticles could be a new way to tackle Acne, one of the most common dermatologic diseases affecting between 40-50 million people each year.
corresponding to red light of a wavelength of 700 nanometers. As more layers were added, the optical gap decreased.
For instance, for five layers, the optical gap value was 0. 8 electron volts, a infrared wavelength of 1550 nanometres.
'"said Subramanian Sankaranarayanan, Argonne computational nanoscientist, who led the simulation work at the Argonne Leadership Computing Facility (ALCF), a DOE Office of Science User Facility.
and Diana Berman were studying the hybrid material in laboratory experiments at Argonne's Tribology Laboratory and the Center for Nanoscale Materials,
They tried incorporating nanodiamond particles into their simulations to see if the hard material could help stabilize the nanoscrolls
The graphene patches spontaneously rolled around the nanodiamonds, which held the scrolls in place and resulted in sustained superlubricity.
The simulation results fed into a new set of experiments with nanodiamonds that confirmed the same."
"Arrayunfortunately, the addition of nanodiamonds did not address the material's aversion to water. The simulations showed that water suppresses the formation of scrolls by increasing the adhesion of graphene to the surface.
and mechanical rotating seals for microelectromechanical and nanoelectromechanical systems. Adding to the material's appeal is a relatively simple
it would leave the graphene and nanodiamonds on one side of a moving part, and diamond-like carbon on the other side.
"Given the advent of computing resources like Aurora and the wide gamut of the available two-dimensional materials and nanoparticle types,
#Transparent, electrically conductive network of encapsulated silver nanowires The electrodes for connections on the"sunny side"of a solar cell need to be not just electrically conductive,
and silver particles with nanoscale dimensions oxidise particularly rapidly; meanwhile, indium is one of the rarest elements on earth crust
Mesh of silver nanowires Manuela Göbelt on the team of Prof. Silke Christiansen has developed now an elegant new solution using only a fraction of the silver
The doctoral student initially made a suspension of silver nanowires in ethanol using wet-chemistry techniques. She then transferred this suspension with a pipette onto a substrate, in this case a silicon solar cell.
the silver nanowires organise themselves into a loose mesh that remains transparent, yet dense enough to form uninterrupted current paths.
This process caused tiny AZO crystals to form on the silver nanowires, enveloped them completely, and finally filled in the interstices.
The silver nanowires measuring about 120 nanometres in diameter, were covered with a layer of about 100 nanometres of AZO
and encapsulated by this process. Quality map calculated Measurements of the electrical conductivity showed that the newly developed composite electrode is comparable to a conventional silver grid electrode.
However, its performance depends on how well the nanowires are interconnected, which is a function of the wire lengths and the concentration of silver nanowires in the suspension.
The scientists were able to specify the degree of networking in advance with computers. Using specially developed image analysis algorithms,
"We are investigating where a given continuous conductive path of nanowires is interrupted to see where the network is not yet optimum,
who heads the Institute of Nanoarchitectures for Energy conversion at HZB and additionally directs a project team at the Max Planck Institute for the Science of Light (MPL).
"The network of silver nanowires is so fine that almost no light for solar energy conversion is lost in the cell due to the shadow,
On the contrary, she hopes"it might even be possible for the silver nanowires to scatter light into the solar cell absorbers in a controlled fashion through
For their experiments, the researchers used thin films of gold that were 120 nanometers thick,
The light source was an array of off-the-shelf LEDS positioned beneath the PCR wells. The peak wavelength of the blue LED light was tuned 450 nanometers
And Yellow fever Researchers in the US have developed a silver nanoparticle-based paper test to simultaneously detect dengue, yellow fever and Ebola.
The test is made from strips of paper containing antibodies attached to triangular silver nanoparticles of varying size according to the disease they recognize
Silver nanoparticles appear as different colours according to their size, so when a patient serum sample migrates through the device,
Warren Chan, an expert in nanomaterials-based diagnostics at the University of Toronto in Canada
The work was published in Nature Nanotechnology on June 8. Neuroscientists still do not understand how the activities of individual brain cells translate to higher cognitive powers such as perception and emotion.
The Harvard team solved these problems by using a mesh of conductive polymer threads with either nanoscale electrodes
Nanowires that poke out can be connected to a computer to take recordings and stimulate cells. So far, the researchers have implanted meshes consisting of 16 electrical elements into two brain regions of anaesthetized mice
and to add hairpin-shaped nanowire probes to the mesh to record electrical activity inside and outside cells.
In a recent paper, published in the journal Nature Nanotechnology a team of Harvard researchers describe the creation of a flexible nanowire mesh with nanoscale electrodes
or transistors placed at each wired junction. The mesh is malleable,"soft as silk, "and spacious, allowing it to naturally incorporate into the brain
Nanowires connecting the mesh with computers in the outside world can either record brain activity or stimulate nearby neurons.
Big Blue's partners are Globalfoundries, Samsung and the State university of New york Polytechnic institute's Colleges of Nanoscale Science and Engineering (SUNY Poly CNSE.
-and nanoscale structures to give the metals their new properties. This work builds on earlier research by the team in which they used a similar laser-patterning technique that turned metals black.
so Bailie did it manually. e used a sheet of plastic with silver nanowires on it, he said. hen we built a tool that uses pressure to transfer the nanowires onto the perovskite cell, kind of like a temporary tattoo.
You just need to rub it to transfer the film. Remarkable efficiency For the experiment, the Stanford team stacked a perovskite solar cell with an efficiency of a 12.7 percent on top of a low-quality silicon cell with an efficiency of just 11.4 percent. y combining two cells
Ripples, wrinkles and sub-10-nanometer pores in the surface and atomic-level imperfections give LIG its ability to store a lot of energy.
Tour is the T. T. and W. F. Chao Chair in Chemistry as well as a professor of materials science and nanoengineering and of computer science and a member of the Richard E. Smalley Institute for Nanoscale Science and Technology.
#Carbon nanotube finding could lead to flexible electronics with longer battery life University of Wisconsin-Madison materials engineers have made a significant leap toward creating higher-performance electronics with improved battery life and the ability to flex
the team has reported the highest-performing carbon nanotube transistors ever demonstrated. In addition to paving the way for improved consumer electronics,
Gopalan and their students reported transistors with an on-off ratio that 1, 000 times better and a conductance that 100 times better than previous state-of-the-art carbon nanotube transistors. arbon nanotubes are very strong and very flexible,
because metallic nanotube impurities act like copper wires and hortthe device. Researchers have struggled also to control the placement and alignment of nanotubes.
Until now, these two challenges have limited the development of high-performance carbon nanotube transistors. Building on more than two decades of carbon nanotube research in the field
the UW-Madison team drew on cutting-edge technologies that use polymers to selectively sort out the semiconducting nanotubes,
achieving a solution of ultra-high-purity semiconducting carbon nanotubes. Previous techniques to align the nanotubes resulted in less than-desirable packing density,
or how close the nanotubes are to one another when they are assembled in a film. However, the UW-Madison researchers pioneered a new technique,
called floating evaporative self-assembly, or FESA, which they described earlier in 2014 in the ACS journal Langmuir.
In that technique, researchers exploited a self-assembly phenomenon triggered by rapidly evaporating a carbon nanotube solution.
The team most recent advance also brings the field closer to realizing carbon nanotube transistors as a feasible replacement for silicon transistors in computer chips and in high-frequency communication devices,
which are rapidly approaching their physical scaling and performance limits. he advance enables new types of electronics that aren possible with the more brittle materials manufacturers are currently using.
wee really made a leap in carbon nanotube transistors. Our carbon nanotube transistors are an order of magnitude better in conductance than the best thin film transistor technologies currently being used commercially
while still switching on and off like a transistor is supposed to function. The researchers have patented their technology through the Wisconsin Alumni Research Foundation
In new findings the researchers have demonstrated how attaching nanodiamonds containing itrogen-vacancy centersto the new metamaterial further enhances the production of single photons, workhorses of quantum information processing,
cryptography and communications technologies. hese results indicate that the brightness of the nanodiamond-based single-photon emitter could be enhanced substantially by placing such an emitter on the surface of the hyperbolic metamaterial,
Placing a nanodiamond containing an NV center on the surface of hyperbolic metamaterials not only enhances the emission of photons,
He and Kildishev are working with a team of researchers led by Vladimir M. Shalaev, scientific director of nanophotonics at Purdue Birck Nanotechnology Center and a distinguished professor of electrical and computer engineering,
the optical metamaterials owe their unusual potential to precision engineering on the scale of nanometers. Quantum computers would take advantage of phenomena described by quantum theory called uperpositionand ntanglement.
Their discovery that nanosheets of manganese dioxide can maintain a rechargable sulphur cathode helps to overcome a primary hurdle to building a Li-S battery.
Nazar group is known best for their 2009 Nature Materials paper demonstrating the feasibility of a Li-S battery using nanomaterials.
While the researchers found since then that nanosheets of manganese dioxide work even better than titanium oxides
They found that the oxygenated surface of the ultrathin manganese dioxide nanosheet chemically recycles the sulphides in a two-step process involving a surface-bound intermediate, polythiosulfate.
Their work was published this week in the journal Nature Nanotechnology. Until a few years ago, human-made silicene was a purely theoretical material.
and added a nanometer-thick layer of alumina on top. Because of these protective layers the team could safely peel it of its base and transfer it silverside-up to an oxidized-silicon substrate.
Inside the fibre however there is a carefully designed nanostructure which allows short wavelengths to travel through the fibre faster than longer ones.
The nanostructure inside the fibre is called agomewhich is Japanese for asket weave This special fibre that allows undistorted transmission of these extremely short pulses was designed
#Nanoscale mirrored cavities amplify connect quantum memories The idea of computing systems based on controlling atomic spins just got a boost from new research performed at the Massachusetts institute of technology (MIT) and the U s. Department of energy (DOE) Brookhaven National Laboratory.
Photons that enter these nanoscale funhouses bounce back and forth up to 10 000 times, greatly enhancing their chance of interacting with the electrons in the NV center.
Scientists at the Center for Functional Nanomaterials (CFN), a DOE Office of Science User Facility at Brookhaven Lab, helped to fabricate
Photons that enter these nanoscale funhouses bounce back and forth up to 10,000 times, greatly enhancing their chance of interacting with the electrons in the NV center.
In our case, we overcame the problem that hundred-nanometer-thick diamond membranes are too small and too uneven.
about 20 nanometers in size the same size range as the smallest features that can now be produced in microchips.
and uses it to push the rings together. he tiny molecular machine threads the rings around a nanoscopic chain a sort of axle and squeezes the rings together,
with only a few nanometers separating them. At present, the artificial molecular pump is able to force only two rings together,
clear nanocellulose paper made out of wood flour and infused it with biocompatible quantum dots tiny, semiconducting crystals made out of zinc and selenium.
#Engineering Phase changes in Nanoparticle Arrays Scientists at the U s. Department of energy Brookhaven National Laboratory have taken just a big step toward the goal of engineering dynamic nanomaterials
In a paper appearing innature Materials, they describe a way to selectively rearrange the nanoparticles in three-dimensional arrays to produce different configurations,
Introducing eprogrammingdna strands into an already assembled nanoparticle array triggers a transition from a other phase,
Such phase-changes could potentially be used to switch a material properties on demand. ne of the goals in nanoparticle self-assembly has been to create structures by design,
who led the work at Brookhavencenter for Functional Nanomaterials (CFN), a DOE Office of Science User Facility. ntil now,
DNA-directed rearrangementthis latest advance in nanoscale engineering builds on the team previous work developing ways to get nanoparticles to self-assemble into complex composite arrays,
they started with an assembly of nanoparticles already linked in a regular array by the complementary binding of the A t, G,
or a combination of these forces between particles. e know that properties of materials built from nanoparticles are strongly dependent on their arrangements,
the reprogramming DNA strands adhere to open binding sites on the already assembled nanoparticles. These strands exert additional forces on the linked-up nanoparticles. y introducing different types of reprogramming DNA strands,
we modify the DNA shells surrounding the nanoparticles, explained CFN postdoctoral fellow Yugang Zhang, the lead author on the paper. ltering these shells can selectively shift the particle-particle interactions,
either by increasing both attraction and repulsion, or by separately increasing only attraction or only repulsion.
the team demonstrated that they could switch their original nanoparticle array, the otherphase, into multiple different daughter phases with precision control.
and accompanying theoretical analysis confirm that reprogramming DNA-mediated interactions among nanoparticles is a viable way to achieve this goal. ource:
The team, from the Centre for Nanoscale Biophotonics (CNBP), an Australian Research Council (ARC) Centre of Excellence, created a simple,
A free application to convert your smartphone into a bio-sensing readout device will be available for download from the Centre for Nanoscale Biophotonics web site www. cnbp. org. au/smartphone biosensing c
Non-aqueous solvent supports DNA NANOTECHNOLOGY Scientists around the world are using the programmability of DNA to assemble complex nanometer scale structures.
Researchers at the Georgia Institute of technology have shown now that they can assemble DNA NANOSTRUCTURES in a solvent containing no water.
The research could open up new applications for DNA NANOTECHNOLOGY, and help apply DNA technology to the fabrication of nanoscale semiconductor and plasmonic structures.
Sponsored by the National Science Foundation and NASA, the research will be published as the cover story in Volume 54, Issue 23 of the journal Angewandte Chemie International Edition.
NA nanotechnology structures are getting more and more complex, and this solvent could help researchers that are working in this growing field,
we have shown that DNA NANOSTRUCTURES can be assembled in a water-free solvent, and that we can mix water with the same solvent to speed up the assembly.
The assembly rate of DNA NANOSTRUCTURES can be very slow, and depends strongly on temperature. Raising the temperature increases this rate,
This solvent also offers enhanced properties for nanotechnology and for the stability of these nanomaterials in solution.
Gállego had worked in DNA NANOTECHNOLOGY before coming to Georgia Tech, and wasconvinced that alternative solvents could advance this field.
At Georgia Tech he evaluated new solvents for use with DNA NANOSTRUCTURES solvents that had been designed for other purposes.
Structures that fail to completely assemble are a major source of low yields in the DNA nanofabrication process. his solvent could provide a new tool to make more complicated designs with DNA
he added. inetic traps are among the bottlenecks for producing more complicated DNA NANOSTRUCTURES. Glycholine is miscible in water,
A key feature of the new solvent system is that it does not require changes to existing DNA NANOTECHNOLOGY designs that were developed for water. ou can go back
The solvent system could improve the combined use of metallic nanoparticles and DNA based materials. In the typical aqueous solvents where DNA NANOTECHNOLOGY is performed,
nanoparticles are prone to aggregation. The solvent low volatility could also allow storage of assembled DNA structures without the concern that a water-based medium would dry out.
The research team, which also included Martha Grover from Georgia Tech School of Chemical & Biomolecular engineering, has used so far the solvent to assemble three structures,
and investigate other solvents that may have additional properties attractive for nanotechnology applications. e were confident all along that we would find a solvent that would be compatible with existing DNA NANOTECHNOLOGY, added Hud,
because DNA NANOTECHNOLOGY was developed in water. The research on water-free solvents grew out of Georgia Tech research into the origins of life.
while also having applications in nanotechnology. n
#DNA mutations get harder to hide Rice university researchers have developed a method to detect rare DNA mutations with an approach hundreds of times more powerful than current methods.
has been developing sustainable nanomaterials since 2009. f you take a big tree and cut it down to the individual fiber,
These images show differential conductance through the quantum dot as a function of the gate voltage that controls the number of electrons in the dot (x-axis) and the applied magnetic field (y-axis).
Professor of Chemistry, an international team of researchers developed a method for fabricating nanoscale electronic scaffolds that can be injected via syringe.
The study is described in a June 8 paper in Nature Nanotechnology. Contributing to the work were Jia Liu, Tian-Ming Fu, Zengguang Cheng, Guosong Hong, Tao Zhou, Lihua Jin, Madhavi Duvvuri, Zhe Jiang, Peter
researchers lay out a mesh of nanowires sandwiched in layers of organic polymer. The first layer is dissolved then, leaving the flexible mesh,
#Nanomaterial Self-Assembly Imaged In real time A team of researchers from UC San diego, Florida State university and Pacific Northwest National Laboratories has visualized for the first time the growth of anoscalechemical complexes in real time,
which will make possible many future advances in nanotechnology, is detailed in a paper published online in the Journal of the American Chemical Society.
for example, to better understand the stepwise formation of nanostructures. Previously, scientists could examine changes in nanostructures only by looking at the large-scale alterations of a bulk population of particles
or by taking creen shotsin a static fashion of individual nanostructures with electron microscopy. hat process is like taking photos every 10 minutes of a football game
and then trying to piece these photos together to tell the story of what is really a highly dynamic process,
chair of UC San diego Department of chemistry and Biochemistry. ntil now, this was the state of the art in terms of how we could document how nanostructures formed.
by literally videoing these processes on the nanoscale level using an electron microscope. The development employed a recently developed process called Liquid Cell Transmission Electron microscopy.
or TEM, has long been used by scientists to image nanoscale materials and understand nanoscale structure.
While advances in Liquid Cell TEM or LCTEM, had permitted scientists to visualize the motion of nanoscale objects in liquids,
researchers had figured not yet out a way to use it to visualize the growth of complex self-assembled,
chemical nanostructures. e showed for the first time that this technique can be used to observe the growth of complex organic-inorganic hybrid materials,
providing an unprecedented understanding of their formation, said Gianneschi. his demonstration marks a significant step forward in LCTEM becoming essential for our understanding of nanoscale processes for all materials in liquids.
if these nanostructures would survive the experiment. This is necessary because materials are susceptible to being destroyed by the high energy electron beam that is used to image them.
length scales can be observed that are relevant to nanoscale materials and processes. In terms of imaging dynamics like this, we believe it will impact how nanotechnology is developed in the future. o
#UCLA researchers discover molecular rules that govern autoimmune disorders An international team led by researchers at UCLA Henry Samueli School of engineering
and Applied science and California Nanosystems Institute has identified an unexpectedly general set of rules that determine which molecules can cause the immune system to become vulnerable to the autoimmune disorders lupus and psoriasis.
#Ultrafast heat conduction can manipulate nanoscale magnets Researchers at the University of Illinois at Urbana-Champaign have uncovered physical mechanisms allowing the manipulation of magnetic information with heat.
and highly desirable way to manipulate magnetization at the nanoscale. This is a schematic, cutaway view of the geometry used to generate currents of spin from currents of heat.
and enables the manipulation of nanomagnets with spin currents rather than magnetic fields, explained Gyung-Min Choi,
It is made from gelatin-based biomaterials reinforced with nanoparticles and seeded with cells, and it mimics the anatomical microenvironment of lymphoid tissue.
is a soft, nanocomposite biomaterial. The engineers reinforced the material with silicate nanoparticles to keep the structure from melting at the physiologically relevant temperature of 98.6 degrees.
The organ could lead to increased understanding of B cell functions, an area of study that typically relies on animal models to observe how the cells develop and mature.
Using the Center for Nanoscale Materials a DOE Office of Science user facility at Argonne, they built a constricted wire out of a three-layered structure in
A protein nanoparticle called OD-GT8 60mer which already proved to help immunity of mouse models to cope with HIV,
During it scientists tested a protein nanoparticle designed to bind and activate B cells needed to fight HIV.
The scientists devised a new arrangement of solar cell ingredients, with bundles of polymer donors (green rods) and neatly organized fullerene acceptors (purple, tan.
In photosynthesis, plants that are exposed to sunlight use carefully organized nanoscale structures within their cells to rapidly separate charges pulling electrons away from the positively charged molecule that is left behind,
you can vastly improve the retention of energy. he two components that make the UCLA-developed system work are a polymer donor and a nanoscale fullerene acceptor.
The polymer donor absorbs sunlight and passes electrons to the fullerene acceptor; the process generates electrical energy.
The plastic materials, called organic photovoltaics, are organized typically like a plate of cooked pasta a disorganized mass of long, skinny polymer paghettiwith random fullerene eatballs.
Some fullerene meatballs are designed to sit inside the spaghetti bundles, but others are forced to stay on the outside.
The fullerenes inside the structure take electrons from the polymers and toss them to the outside fullerene
#New way to produce carbon nanoparticles found only honey and microwave needed Researchers at University of Illinois have created a new inexpensive and simple way to produce carbon nanoparticles.
They are small enough to evade the body immune system, reflect light in the near-infrared range for easy detection,
However, when usual methods to produce carbon nanoparticles are rather complex and can take days,
and time that these carbon nanoparticles can virtually be made at home. Dipanjan Pan bioengineering professor one of authors of the study, said that you just have to mix honey
but that is nanoparticles with high luminescence This method is extremely simple and highly scalable for eventual clinical use.
These carbon nanoparticles produced in such a simple and inexpensive way have several attractive properties.
Finally, carbon nanoparticles are rather small, less than eight nanometres in diameter (in comparison, a human hair is 80,000 to 100,000 nanometres thick).
This is very important and useful, since human immune system fails to recognize anything under 10 nanometres,
which allows for a better therapeutic potential. The team of researchers tested the therapeutic potential of these carbon nanoparticles by loading them with an anti-melanoma drug
and mixing them in a topical solution that was applied to pig skin. However, scientists have to make sure they coated particles properly,
so they used vibrational spectroscopic techniques to identify the molecular structure of the nanoparticles and their cargo.
The experiment showed that the carbon nanoparticles did not release the drug payload at room temperature
Study showed that cancer cells were affected positively by drugs delivered by these carbon nanoparticles. These carbon nanoparticles,
despite being made from honey in the microwave, are very useful indeed. They can be used to carry a variety of different drugs into a human body.
having in mind that currently production of carbon nanoparticles requires expensive equipment and purification processes that can take days.
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