Synopsis: Domenii: Medical equipment:


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Hospital patients often acquire urinary tract infections via infected catheters and so untreated infections are a huge problem faced by healthcare providers around the world.


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The Corevalveevolut R System is deployed with a catheter, which is inserted into an artery and guided to the heart.

It is deployed with a catheter, which is inserted into an artery and guided to the heart.


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even when the surgical instrument is cleaned.""As a result, he said, "We're advocating a precautionary approach.


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the transmitting power of the magnetic signals sent through the body is expected to be many times lower than that of MRI SCANNERS and wireless implant devices.


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a brain-driven clock that controls the rhythms of various biological processes, from digestion to blood pressure, heart rate to waking and sleeping.


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#Using ultrasound to clean medical instruments Researchers from the University of Southampton have demonstrated how a pioneering ultrasonic device can significantly improve the cleaning of medical instruments

"In the absence of sufficient cleaning of medical instruments, contamination and infection can result in serious consequences for the health sector and remains a significant challenge.


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or organ surfaces, suggest the nanomesh"might be implanted in the body as a pacemaker electrode,


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It may be used to cover titanium implants (orthopaedic prostheses, pacemakers...prevent or control postoperative infections. Other frequently used medical devices that cause numerous infectious problems, such as catheters, may also benefit.

These results are published in the journal Advanced Healthcare Materials. Implantable medical devices (prosthesis/pacemakers) are an ideal interface for microorganisms,

which can easily colonize their surface. As such, bacterial infection may occur and lead to an inflammatory reaction.

Silver is an anti-infectious material currently used on catheters and dressings. This strategy allows us to extend antimicrobial activity in the long term"explains Philippe Lavalle, Research director at Inserm.


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or"respondent,"wears a cap connected to an electroencephalography (EEG) machine that records electrical brain activity.


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the prosthetic valve is compressed to the thickness of a pencil and loaded into a catheter.

The catheter is inserted into the patient through a small incision made either at the leg

The catheter will then be used to send the device to the patient's diseased mitral valve.


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Also, certain medical imaging techniques could benefit from the enhanced characteristics of the novel X-ray source s


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It is inserted directly into the bladder through a catheter. BCG prevents new tumours from appearing,


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a conglomeration of conditions including increased blood pressure, high levels of blood sugar, excessive body fat around the abdomen and waist,

Deboer and Gurka examined metabolic severity scores from children in the 1970s that assessed body mass index (BMI), systolic blood pressure, fasting triglycerides, HDL cholesterol and fasting glucose.


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"Therapeutic Applications of Ultrasound")have developed just a noninvasive brain imaging method using MRI that provides the same information as physical palpation.


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synthetic version of the precious gem can light up early-stage cancers in nontoxic, noninvasive Magnetic resonance imaging (MRI) scans.

a process of aligning atoms inside a diamond so they create a signal detectable by an MRI SCANNER."


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electrical devices (pacemakers or defibrillators) or drugs (eg beta blockers. However, these methods are relatively crude: they can stop


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and 15 healthy control volunteers were monitored also using functional magnetic resonance imaging (fmri) and fiber tractography. Participants were asked to respond to commands,


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The new sensor uses a special variant of an imaging technology called optical coherence tomography (OCT). OCT is used already for medical imaging


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Dr. Lingnau and her team used functional magnetic resonance imaging (fmri) while participants planned and performed simple hand movements inside the scanner.


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a manually driven multi-syringe device capable of performing up to 80 simultaneous tests from whole blood samples at any one time;


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Researchers could track this activity using magnetic resonance imaging (MRI), potentially allowing them to observe communication between neurons, activation of immune cells,


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One specific application of this new technology is developing patient-specific catheters, especially for premature newborns.

Today's catheters only come in standard sizes and shapes which means they cannot accommodate the needs of all premature babies."

"If you can print a catheter whose geometry is specific to the individual patient, you can insert it up to a certain critical spot,

000 Small Business Technology Transfer grant from the National institutes of health to develop the neonatal catheters with a local company."

and they penetrate not only our bodies--think of CT SCANS--but many other materials.""Finally, in a process called"stereolithography,"they build the product,


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No urinary catheter is needed post-procedure. Side effects may include burning and blood in the urine during the first 24 hours after the procedure.


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The Mito Test uses near infrared spectroscopy, a special type of light beamed through the skin to measure the oxygen levels in muscle mitochondria.


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#Brain imaging Explains Reason For good and Poor Language Outcomes in ASD Toddlers Using functional magnetic resonance imaging (fmri), University of California,

San diego School of medicine researchers say it may be possible to predict future language development outcomes in toddlers with autistic spectrum disorder (ASD),


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Blood samples and blood pressure readings were collected, as well as information about stress and perceived discrimination through interviews.

and blood pressure. didn expect that discrimination would have such a strong relationship with these particular markers of cardiovascular disease risk in kids this young,


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they found that by inserting a temporary catheter tube under the skin, they could induce new blood vessels to grow, making an ideal home for islet transplantation. n the paper,


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labeled with the radioactive substance technetium-99m. mages we took using single photon emission computed tomography show that both the antibody


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Magnetic resonance imaging and other scanning technologies can indicate the size of a tumor, while the most detailed information about how well a treatment is working comes from pathologistsexaminations of tissue taken in biopsies.

It contains 10 microliters of chemical contrast agents typically used for magnetic resonance imaging (MRI) and an onboard circuit to communicate with the external reader device.

Four years ago, his team built a similar implantable sensor that could be read by an MRI SCANNER.

it like taking blood pressure. It a simple measurement. You get the readout and move on, says Ralph Weissleder,

because they have implantable electronics, like pacemakers and defibrillators, he says. ee making these sensors out of materials that are in these kinds of long-term implants,


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#Telltale biomarker detects early breast cancer in NIH-funded study Researchers have shown that magnetic resonance imaging (MRI) can detect the earliest signs of breast cancer recurrence and fast-growing tumors.


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For the first time, Carnegie mellon University Brainhub scientists have used a noninvasive brain imaging tool to detect the pathways that connect the parts of the basal ganglia.

Published in Neuroimage the research provides a better understanding of this area circuitry, which could potentially lead to technologies to help track disease progression for Parkinson and Huntington disease and other neurological disorders. linically,

it is difficult to see the pathways within the basal ganglia with neuroimaging techniques, like the ever popular MRI,


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and sophisticated EEG, sleep and biochemical studies are performed. This includes the sequencing of their entire genome.


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#Link found between blood pressure and diabetes in major new study High blood pressure sufferers have an almost 60%greater chance of developing diabetes, according to a major global study.

stroke and heart failure. igh blood pressure affects even more people at least 4. 6 million Australians. onfirming this connection reliably provides new hope for those people

For every 20 mm mercury increase on the measurement gauge, in systolic blood pressure there was a 58%higher risk of developing diabetes.

For every 10 mm mercury increase in systolic blood pressure there was a 52%higher risk of developing diabetes Higher blood pressure was associated also with a higher risk of new onset diabetes in a wide

overweight and obese individuals The relative association between blood pressure and diabetes decreased as body mass index (BMI)

increase of mercury in systolic blood pressure, he said. sing the two complementary approaches has given us even greater confidence in the results.

Professor Rahimi said researchers could now examine the causal relationship between blood pressure and diabetes. t a minimum we know for certain that the link exists,

whether lowering blood pressure is an effective treatment or reduces the risk of getting diabetes. hese are exciting results and


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UV LIGHT enabled catheter fixes holes in the heart without invasive surgery Researchers from Boston Children Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard university,

Harvard John A. Paulson School of engineering and Applied sciences (SEAS) and the Karp Lab at Brigham and Women Hospital have designed jointly a specialized catheter for fixing holes in the heart using a biodegradable adhesive and patch.

As the team reports in Science Translational Medicine, the catheter has been used successfully in animal studies to facilitate hole closure without the need for open heart surgery.

Their newly designed catheter device utilizes UV LIGHT technology and can be used to place the patch in a beating heart.

The catheter is inserted through a vein in the neck or groin and directed to the defect within the heart.

Once the catheter is in place, the clinician opens two positioning balloons: one around the front end of the catheter, passing through the hole,

and one on the other side of the heart wall. The clinician then deploys the patch and turns on the catheter UV LIGHT.

The light reflects off of the balloon shiny interior and activates the patch adhesive coating.

and the catheter is withdrawn. Over time, normal tissue growth resumes and heart tissue grows over the patch.


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a conglomeration of conditions including increased blood pressure, high levels of blood sugar, excessive body fat around the abdomen and waist,

Deboer and Gurka examined metabolic severity scores from children in the 1970s that assessed body mass index, systolic blood pressure, fasting triglycerides, HDL cholesterol (the so-called oodcholesterol) and fasting glucose.


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One possible application for this augmented microscope is laser surgery. In the past, surgeons could not see the laser beam through the standard stereomicroscope, nor anatomical details in the NIR images.


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herapeutic Applications of Ultrasound have developed just a noninvasive brain imaging method using MRI that provides the same information as physical palpation.


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electrical devices (pacemakers or defibrillators) or drugs (eg beta blockers. However, these methods are relatively crude: they can stop


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electrical devices (pacemakers or defibrillators) or drugs (eg beta blockers. However, these methods are relatively crude: they can stop


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It has been used in various therapies as a way to remove excess fibrin proteins from the blood to treat thrombosis and as a topical hemostat.

which can be loaded into a syringe and injected at the site of a wound, where they reassemble themselves into a gel.

the hydrogel without batroxobin, the batroxobin without the hydrogel, a current clinical hemostat known as Gelfoam and an alternative self-assembling hemostat known as Puramatrix and found that none were as effective, especially in the presence of anticoagulants.


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and hooked it up to an electroencephalography machine. The sensors were able to detect a special brain signal present only when the subject eyes were closed classic electroencephalogram testing procedure.

such as the heart electrical activity detected during an electrocardiogram or EKG e


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#Bacterial hole puncher could be new broad-spectrum antibiotic Bacteria have many methods of adapting to resist antibiotics,


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It can also be treated with a procedure called cardiac ablation that burns away the malfunctioning cells using a high-powered laser that threaded into the heart on a catheter.


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Magnetic resonance imaging or MRI, utilizes magnetic fields. A cloaking device for magnetic fields could make it easier for doctors to utilize MRI during operations by idingthe field from surgical instruments. hat just one application.

But who knows what other applications there could be for this theory, which works for almost any kind of wave, said Uhlmann.


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and tagging them for medical imaging or drug targeting. The study by researchers Cheulhee Jung, Peter B. Allen and Andrew Ellington, published this week in the journal Nature Nanotechnology,


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In a 1998 experiment, also at Case Western, a volunteer named Jim Jatich used signals collected from an EEG cap he wore over his head to trigger an early FES device known as Freehand,

which Jatich was able to generate by modulating his EEG wave. Implants placed in contact with the brain motor cortex can gather far more detailed information


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and use it to detect vital signs like heartbeat and blood pressure. e


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#Graphene's thermoelectric properties to help cars recover lost thermal energy Charging bateries or running air conditioning could be assisted by energy from fuel normally wasted as heat emissions One of the less well-known properties of graphene could enable the carbonaceous wonder-material to help combustion engine vehicles to make better use of the energy from their fuel by converting waste heat into electricity


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such as cardiac surgeryhe says. thin-whiskered catheter tip could be used during surgery to track the relative position inside the heart,


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to hearing aids and cochlear implants. ee invented a sensing system that can efficiently, reliably and inexpensively solve an interesting problem that modern technology has to deal with on a daily basis,

it should also be possible to improve the sound fidelity and increase functionalities for applications like hearing aids and cochlear implants.


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Using an electroencephalogram (EEG) cap, the system allows users to move forwards, turn left and right, sit

and when the user focusses their attention on a specific LED this frequency is reflected within the EEG readout.

one of the paper authors. he EEG signal gets buried under all this noise but our system is able to separate not only the EEG signal,

but the frequency of the flickering LED within this signal. Although the paper reports tests on healthy individuals,

with EEG caps and hardware now emerging on the consumer market. It only took volunteers a few minutes to be trained in how to operate the system


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including power generation in wind turbines, memory storage, and medical imaging. However, only three metals iron cobalt and nickel-are naturally ferromagnetic,


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#Tadpole endoscope offers new hope for gastrointestinal cancer detection Hong kong researchers have devised a swimming housing for a capsule endoscopy camera which can be steered around to provide better images inside the stomach

The tadpole endoscope, with drive unit at the back This is where the tadpole comes in, with researchers Yong Zhong and Ruxu Du from the Institute of Precision Engineering and Philip W Y Chiu of the Jockey club Minimally Invasive

both at the Chinese University of Hong kong, attempting to mimic the movement of the larval amphibians to design a capsule endoscope with a controllable swimming action that doctors can steer around inside the stomach to provide a guided tour,

The tadpole endoscope, swimming in a stomach-shaped test tank The capsule itself is a simple structure, 13mm in diameter,


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During the conventional prosthetic tuning process, a prosthetist adjusts the powered prosthesis system so that it exerts the power necessary to recreate those normal joint motions while walking.

or gait, can affect the prosthesis ability to achieve that aturaljoint angle. The automatic-tuning algorithm takes a similar approach,

But it is able to adjust the amount of power the prosthesis receives in real time, in order to maintain the proper angle.

the algorithm could provide more power to a prosthesis when a patient carries a heavy suitcase through an airport,


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Dr Vikas Shah a consultant radiologist at University Hospitals Leicester. upload radiology cases such as x-rays or CT SCANS with a question or two,


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using it to control the amount of material deposited by each layer through the pressure exerted by the piston of a syringe.

because it has to enter the syringe in liquid form and then solidify to form layers


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Eight patients developed severe CRS which required treatment for low blood pressure and breathing difficulties. Nine patients were treated with tocilizumab an immunosuppressant drug that blocks the effects of the inflammatory cytokine IL-6


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a combination of obesity/abdominal adiposity insulin resistance raise levels of lipids in the blood and raised blood pressure.


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Yohimbin must be modified to minimise side-effects in this case raised blood pressure and we need the help of a cooperation partner to achieve this.


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bacteria From joint replacements to cardiac implants and dialysis machines medical devices enhance or save lives on a daily basis

and catheters coated with the material in large blood vessels in pigs and it prevented blood from clotting for at least eight hours without the use of blood thinners such as heparin.

While most of the team's demonstrations were performed on medical devices such as catheters and perfusion tubing using relatively simple setups they say there is a lot more on the horizon.

We feel this is just the beginning of how we might test this for use in the clinic said co-lead author Daniel Leslie Ph d. a Wyss Institute Staff Scientist who aims to test it on more complex systems such as dialysis machines


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Currently physicians diagnose brain swelling with imaging techniques such as CT SCANS or by monitoring intracranial pressure (ICP) directly.

Our team is now considering how to incorporate this device into a catheter that could siphon out cerebral spinal fluid


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and Bruce Maryanoff, formerly at Johnson & johnson and currently a visiting scholar at TSRI, the researchers tested this synthetic peptide in a mouse model prone to atherosclerosis.


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and vital-sign data (such as body temperature heart rate and blood pressure) in the electronic health record of hospital inpatients to identify those at risk for sepsis.


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An endoscope is inserted through one or two small incisions in the abdominal wall allowing the internal organs to be visualized for surgery.

The same cannot be said for surgical instruments. In certain types of endoscope, the tip can be oriented at different angles."

"This basic control mechanism, which demands great dexterity and even physical strength on the part of the surgeon, has changed barely

Modern endoscopes are equipped additionally with tiny pincers, clamps or scissors for removing tissue samples, for example.

The cable mechanism transmits the surgeon's hand movements at one end to the tiny instruments at the other extremity of the endoscope.

To control the attached instruments and orient the tip of the endoscope, the surgeon manipulates a hydraulic cylinder

using both rigid endoscope tips and simple gripping tools. Laboratory prototypes with flexible tips have also been tested.


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In January 2013 a Swedish arm amputee was the first person in the world to receive a prosthesis with a direct connection to bone, nerves and muscles.

Before the surgery, his prosthesis was controlled via electrodes placed over the skin. Robotic prostheses can be advanced very,

The patient is also one of the first in the world to take part in an effort to achieve long-term sensation via the prosthesis.

"Reliable communication between the prosthesis and the body has been the missing link for the clinical implementation of neural control and sensory feedback,

Today, no patient walks around with a prosthesis that provides such information, but we are working towards changing that in the very short term."

"The new technology is based on the OPRA treatment (osseointegrated prosthesis for the rehabilitation of amputees),

where the prosthesis is fixated then. Electrodes are implanted in nerves and muscles as the interfaces to the biological control system.

and easy attachment/detachment Increased sensory feedback due to the direct transmission of forces and vibrations to the bone (osseoperception) The prosthesis can be worn all day,

Due to the intimate connection, the patients can control the prosthesis with less effort and more precisely,

and still maintain control of the prosthesis. More motor signals can be obtained from muscles and nerves,

so that more movements can be controlled intuitively in the prosthesis. After the first fitting of the controller, little or no recalibration is required

because there is no need to reposition the electrodes on every occasion the prosthesis is worn (as opposed to superficial electrodes).


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Both procedures are performed by snaking catheters, typically from a blood vessel in the groin, up to the diseased valve.


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The NIST system is similar to optical coherence tomography for example but can operate much farther away from the target


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The Cedars-Sinai surgeons highlight the advantages of a spinal navigation technique that uses high-speed computerized tomography (CT) imaging to navigate in and around the spinal column from different angles.

The computerized navigation system uses a mobile CT SCANNER to take cross-sectional images of the spine while a patient is in surgery.

which displays them on overhead monitors that allow precise tracking of surgical instruments as surgeons insert screws for reconstruction

One of the Cedars-Sinai studies showed that the mobile CT SCANNER and computer-aided system used during minimally invasive surgery increased the accuracy of screw placement into vertebral pedicle bones.

and the mobile CT SCANNER allowed for more accurate surgical placement even within the narrowest parts of the thoracic spine particularly challenging regions in women


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you could potentially get enough cells from just a normal syringe-based blood draw, run it through a bedside device that has the antigen you want to vaccinate against,


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the researchers first used functional magnetic resonance imaging to identify two precise regions of his parietal cortex that activated when he imagined reaching and grasping motions.


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#Clinicloud's Bluetooth-Enabled Stethoscope And Thermometer Lets Doctors Check Your Vitals From The Cloud We are getting that much closer to building the doctor office of the future right within our homes today.

Digital health diagnostic tools startup Clinicloud has launched a line of Bluetooth-connected stethoscopes and thermometers that enable consumers to check their own vitals

The physician can then give a diagnosis without patients having to leave their homes. he stethoscope

Customers can pre-order the Clinicloud stethoscope and thermometer kit for $109, though prices are expected to go up to $149 next month.

Whereas a basic stethoscope is about $5 to $25 on Amazon, and a regular thermometer goes for around $40 on the high-end.


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In March Herr gave a headline-grabbing TED talk about work in his lab to create a special prosthesis that allowed Adrianne Haslet-Davis a dancer

I quickly abandoned this notion that the prosthesis has to look like a human limb and

His lab's work to model the human ankle joint ultimately led to the development of the prosthesis Herr uses today sold as the Biom T2 by his startup company Biom (formerly called iwalk.

and ankle prosthesis that behaves as he puts it more like a motorcycle than a bicycle meaning that it puts energy into the system rather than relying solely on human power.

and reprogrammed the prosthesis with algorithms that would allow it to execute the necessary rotations.


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#Wireless Power for Minuscule Medical Implants Medical implants like pacemakers deep brain stimulators and cochlear implants could someday be joined by still more bioelectronic gadgets devices that regulate insulin levels control

or treat brain injuries (see Nerve-Stimulating Implant Could Lower Blood pressure). But before we re all riddled with electronics researchers have to figure out how to power it all.

Pacemaker batteries are too clunky for tiny devices saddled up to nerves and existing wireless methods such as those used for cochlear implants won t work with devices buried deep in the body.

To test their new powering scheme the Stanford group implanted a pacemaker about the size of a grain of rice in a rabbit

The setup worked with about 0. 1 percent efficiency meaning that nearly all the energy sent from the conductive material to the pacemaker was wasted.


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she said. ust as people with hearing problems benefit from a hearing aid, people with social and emotional problems can benefit from systems that help them understand emotions.


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#Nerve-Stimulating Implant Could Lower Blood pressure An implantable device that reduces blood pressure by stimulating a nerve in the neck could someday be an alternative to drugs for controlling hypertension.

An implantable device would allow reducing the blood pressure in these patients either alone or in combination with the already applied medication says Dennis Plachta a microsystems engineer at the University of Freiburg in Germany.

The 20-millimeter-long cuff positions a set of electrodes on a region of the nerve that the team determined would specifically stimulate the changes in blood pressure.

and found that a certain stimulation pattern could reduce the rodents blood pressure by 40 percent without any major side effects.

He says all his patients are on several blood pressure medications and some find that side effects make the drug regimens difficult to maintain.

The worst part is that the blood pressure is still high which means they are at high risk for stroke heart failure

Pacemakers for heart patients are known perhaps best but electrical devices are used also to control Parkinson s disease and experimentally some psychiatric conditions (see Brain Pacemakers

and Brain Implants Can Rest Misfiring Circuits). They may be helpful even for such unlikely conditions as bladder dysfunction

Bisognano says that nerve stimulation is a logical mechanism for controlling blood pressure. It is well known that the nervous system can regulate the tension of the body s arteries

Bisognano has reduced successfully blood pressure with experimental implants that stimulate the carotid artery directly an entirely different design from the implant developed by the German group.

With the new design blood pressure in the rats dropped less than five seconds after the device stimulated the nerve.

and his colleagues are also working on developing an intelligent version of the system that can detect blood pressure


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such as from a CT SCAN of a skull. The new haptic stylus, due out next month from 3d Systems in Rock Hill, South carolina, will cost just $649, down from a range of $2, 400 to $13, 000

he says. ou do a CT SCAN and send the disk back. a


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#Microsoft Readies a Virtual Assistant for the Corporate World Microsoft reputation for innovation has suffered in recent years despite the company undeniable prowess in research and engineering.


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