Another key advance is the use of active, inexpensive catalysts for fuel production. The photoanode requires a catalyst to drive the essential water-splitting reaction.
Rare and expensive metals such as platinum can serve as effective catalysts, but in its work the team discovered that it could create a much cheaper,
This catalyst is among the most active known catalysts for splitting water molecules into oxygen
At its core, however, is a rule known as Heisenberg's uncertainty principle. This states that in any situation in which a particle has linked two properties,
#DNA-guided 3-D printing of human tissue is unveiled Arraythere are few limits to the tissues this technology can mimic,
showing that samples of brain tissue from two human MSA patients were able to transmit the disease to a mouse model for Parkinson's disease,
and that infected mouse brain tissue could itself spread the disease to other mice. The discovery that alpha-synuclein prions can transmit MSA raises a public health concern about treatments
in contrast to the 120 days it takes for the disease to spread to mouse models."
"You have to let the mouse models develop for such a long time that research on cures is really slow to progress.
such as smart watches, fitness trackers and health monitors. All of these devices will need to communicate information with each other.
and display the correct English word for the gesture. As Jafari continues to develop the technology,
he says his team will look to incorporate all of these functions into one wearable device by combining the hardware and reducing the overall size of the required electronics.
so that he or she can understand what is being signed simply by reading the screen of their own device.
what are called CRISPR libraries instead of RNAI screens.""This is a major finding with translational implications for this infection that causes so many deaths worldwide,
and Shtein how to create them in paper using a plotter cutter. Lamoureux then made more precise patterns in Kapton,
One purpose of this experiment was to show we could integrate bacterial catalysts with semiconductor technology.
especially the catalysts that convert water and carbon dioxide into sugars at room temperatures.""This is not about mimicking nature directly
One purpose of this experiment was to show we could integrate bacterial catalysts with semiconductor technology.
especially the catalysts that convert water and carbon dioxide into sugars at room temperatures.""This is not about mimicking nature directly
according to the Active Bacterial Core surveillance report by the Centers for Disease Control and Prevention.
By combining Scales with Abscale--a variation for immunolabeling--and Chemscale--a variation for fluorescent chemical compounds--they generated multicolor high-resolution 3d images of amyloid beta plaques in older mice from a genetic mouse
As well as offering new opportunities for industry, it will stimulate the search for even better basic catalysts
Now, a team led by Wyss Institute Core Faculty member David Mooney, Ph d.,has developed a new strategy--embedding stem cells into porous,
#Building the electron superhighway TV screens that roll up. Roofing tiles that double as solar panels. Sun powered cell phone chargers woven into the fabric of backpacks.
In addition to Kang and Lerner, authors of the study,"Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signaling,"were Bo-Ram Bang, Kyung Ho Han
The oviductosomes from a female mouse were labeled pre with a fluorescent dye and incubated together with the sperm.
and printer right at the hospital to create custom nerve guides right on site to restore nerve function."
and print concentrated viscoelastic inks that allow for the simultaneous control of composition and geometry during printing.
The research was led by Jennifer A. Lewis, the Hansjörg Wyss Professor of Biologically Inspired Engineering at the Harvard John A. Paulson School of engineering and Applied sciences (SEAS) and a Core Faculty member at the Wyss Institute for Biologically Inspired Engineering
This is a crucial step in creating a new generation of foldable electronics--think a flat-screen television that can be rolled up for easy portability--and implantable medical devices.
The researchers used mouse embryonic fibroblast cells to determine biocompatibility; that, along with the fact that the stretchability of gold nanomesh on a slippery substrate resembles the bioenvironment of tissue
and totally redesigned its core to repurpose its infectious capabilities into a safe vehicle for delivering vaccines
a particularly complex BMC that requires a series of protein-protein interactions involving at least six gene products to form a metabolic core that takes CO2 out of the atmosphere and converts it into sugar.
a two-drug combination discovered by UF Health researchers that inhibits tumors and kills cancer cells in mouse models.
Researchers then tested its effectiveness on human pancreatic cells that had been implanted in mouse models. Daily doses of the compound reduced tumor volume by about 50 percent after 25 days, they found.
In testing on two mouse cell lines, the drug combination reduced the viability of cancer cells by about 50 percent
Electronic exchange of data between processors and the memory limits the speed of modern computers.
it is not sufficient to optically connect memory and processor, as the optical signals have to be converted into electric signals again.
but also with latest processors,"Professor Harish Bhaskaran of Oxford university adds. The new memory can store data for decades even
Against the backdrop of healthy mouse tissue, rogue metastatic cells from the human tumor stick out like flares.
The researchers developed a new method using flow cytometry that let them capture individual human metastatic cancer cells traveling through the mouse's blood
Whereas 44 percent of control mice (11 of 25) developed secondary tumors within four weeks, researchers could only find metastatic cells in one drug-treated mouse (4 percent.
The respondent is shown an object (for example, a dog) on a computer screen, and the second participant,
With the click of a mouse, the inquirer sends a question and the respondent answers"yes"or"no"by focusing on one of two flashing LED LIGHTS attached to the monitor,
which flash at different frequencies. A"no"or"yes"answer both send a signal to the inquirer via the Internet
or by the brain signal transmission being interrupted by hardware problems.""While the flashing lights are signals that we're putting into the brain,
Traditional perovskites are typically metal-oxide materials that display a wide range of fascinating electromagnetic properties,
we believe it will be much easier to manufacture a full-scale processor chip than for any of the leading designs,
"He said that a key next step for the project is to identify the right industry partners to work with to manufacture the full-scale quantum processor chip.
Such a full-scale quantum processor would have major applications in the finance, security and healthcare sectors, allowing the identification
Virginia--a liquid-cooled FPGA was operated using a custom processor architecture provided by Altera. With a water inlet temperature of approximately 20 degrees Celsius and an inlet flow rate of 147 milliliters per minute
However, the same technology could also be used to cool CPUS, GPUS and other devices such as power amplifiers,
Preclinical studies using mouse models of bladder cancer have demonstrated the efficacy of the mycobacterium M. brumae in the treatment of this disease.
and represent it on a computer screen. In this article, Inserm researchers, using MRI, have succeeded in detecting natural shear waves in the brain using computational techniques borrowed from seismologists and known as"noise correlation."
#New graphene based inks for high-speed manufacturing of printed electronics A low-cost, high-speed method for printing graphene inks using a conventional roll-to-roll printing process,
the first time that graphene has been used for printing on a large-scale commercial printing press at high speed.
"Being able to produce conductive inks that could effortlessly be used for printing at a commercial scale at a very high speed will open up all kinds of different applications for graphene and other similar materials.""
which is in line with commercial production rates for graphics printing, and far faster than earlier prototypes.
it could also initiate entirely new business opportunities for commercial graphics printers, who could diversify into the electronics sector."
and the Cambridge area in particular, has always been strong in the printing sector, but mostly for graphics printing and packaging,"said Hasan, a Royal Academy of Engineering Research Fellow and a University Lecturer in the Engineering Department."
"We hope to use this strong local expertise to expand our functional ink platform. In addition to cheaper printable electronics, this technology opens up potential application areas such as smart packaging and disposable sensors,
Interestingly, a subsequent challenge with a lethal strain of mouse malaria parasite in these vaccinated animals showed considerable protection against malaria.
reflectors, and USB detectors, combined with the all-plastic housing and lenses will allow for future versions of the prototype to be mass-produced d
and Ear/Harvard Medical school and Boston University have shown successfully neuroprotection in a Parkinson's mouse model using new techniques to deliver drugs across the naturally impenetrable blood-brain barrier.
In mouse models of human glioblastoma, one molecule they found shrank the average tumor size by half.
The most effective of these candidate drug molecules, called SKOG102, shrank human glioblastoma tumors grown in mouse models by an average of 50 percent."
The discovery of magnetoresistance paved the way for magnetic field sensors used in hard disk drives and other devices,
We found that a bilayer structure of graphene and boron nitride displays an extremely large response with magnetic fields.
and finding applications as thermal switches, hard drives and magnetic field sensors. Our technology can even be applied to flexible applications,"added Assoc Prof Yang.
a portable USB-powered film scanner to image the test strips; and a portable computer for real-time data analysis.
which exceeds the hard drive capacity of most computers and would take 100 hours to transfer with a good Internet connection,
"The program is especially useful for biologists who otherwise would have to acquire the skillset and hardware to handle large data
Scientists have experimented for decades with a class of catalysts known as zeolites that transform alcohols such as ethanol into higher-grade hydrocarbons.
Instead, an energy-producing"hydrocarbon pool"mechanism allows the zeolite catalysts to directly produce longer hydrocarbon chains from the original alcohols."
#Researchers develop 3-D printing method for creating patient-specific medical devices A team of researchers at Northeastern University has developed an innovative 3-D printing technology that uses magnetic fields to shape composite materials
"Others have used composite materials in 3-D printing, says Joshua Martin, the doctoral candidate who helped design
Erb and Martin's 3-D printing method aligns each minuscule fiber in the direction that conforms precisely to the geometry of the item being printed."
"The magnets are the defining ingredient in their 3-D printing technology. Erb initially described their role in the composite-making process in a 2012 paper in the journal Science.
They then apply ultralow magnetic fields to individual sections of the composite material--the ceramic fibers immersed in liquid plastic--to align the fibers according to the exacting specifications dictated by the product they are printing."
#3-D printed'building blocks'of Life scientists have developed a 3-D printing method capable of producing highly uniform'blocks'of embryonic stem cells.
"Our next step is to find out more about how we can vary the size of the embryoid body by changing the printing and structural parameters,
In their proof-of-concept study, they sent light from the LED through an optical fiber to stimulate neurons in mouse brain slices.
The core of the project involves recycling local plastic into versatile locksduring volunteer workshops which are used then to build objects such as benches, planters and stages for use within the community.
The Heattech Mirror visually displays the wearer body temperature rising in the mirror. The smart mirror is connected to a thermal camera
390 gram (0. 9-pound) Robohon sports a 2-inch touchscreen, a quad-core CPU, and can connect to 3g, LTE,
The company uses both hardware and software solutions to achieve this. Its system, bearing the catchy name Jamsdefender, combines active noise cancellation, digital volume normalization,
The target was quite modest, especially for a hardware campaign, but the team says it had to balance estimated costs with a realistic crowdfunding target that wouldn deter backers by appearing too lofty.
or suppress infection in mouse and nonhuman primate models of HIV. But these animal models are very rough approximations of human infections,
an approach that is not commonly used for this kind of screen. nitially, the screening results appeared to not have positive hits,
000 cores of the Stampede supercomputer. Grabe was cautious about the potential application of this research,
and significantly increased survival in a mouse model of pancreatic neuroendocrine tumor. Bergers noted that the discovery potentially gives physicians a way to determine how effective anti-VEGF therapy might be in individual patients
says Chris Chang, an expert in catalysts for carbon-neutral energy conversions. n our system, nanowires harvest solar energy and deliver electrons to bacteria,
the researchers reproduced the hyperexcitability of epileptic neurons in mouse brains in vitro. They then injected GABA,
light photo-catalysts and ferroelectric materials in electronics. nalogous to the best metallic conductors such as copper or silver where the current is transported by electron, in d-Bismuth oxide
and others to feel the environments they inhabit through the likes of three-dimensional heads-ups displays. The prototype glove introduced at the George R. Brown School of engineering Design Showcase
The team used mouse models of asthma and human airway tissue from asthmatic and non-asthmatic people to reach their findings.
and that would be drilled core out. So NRL deconstructed the science. They started with purer chemicals. ousy chemicals in,
or reconfigure the hardware to recover from a failure, on the fly. In March, the team tested the autonomous mission-planning system during a research cruise off the western coast of Australia.
but this is the first device that combines the imaging technology with hardware and software automation to create a complete diagnostic solution,
microcontrollers, gears, circuitry and a USB port. Control of the device is automated through an app the researchers developed for this purpose.
With a single touch of the screen by the healthcare worker, the phone communicates wirelessly via Bluetooth to controllers in the base to process
The worm count is displayed then on the screen. Fletcher said previous field tests revealed that automation helped reduce the rate of human error.
starting from the time the sample is inserted to the display of the results. Pricking a finger
paving the way for high-density storage to move from hard disks onto integrated circuits. This image taken from a computer simulation shows nanomagnets tilted at various angles,
These include a computer hard disk drive where data are stored and the various kinds of random-access memory,
or RAM, on the integrated circuits of the central processing unit, or CPU, where calculations and logic operations are performed.
A large portion of the energy used in computing is spent on transferring data from one type of memory to another.
and color of optical materials used in computer screens along with other consumer products. The work is centered on enhancing the arrangement of colloidsmall particles suspended within a fluid medium.
said Wyss Core Faculty member George Church, Ph d, . who is a pioneer in the converging fields of synthetic biology, metabolic engineering, and genetics.
yet too small to trigger the thermonuclear reactions at their cores that power stars. The astronomers said their observations of LSR J1835+3259 indicate that the coolest stars
which causes the Earth auroral displays the planet magnetic field interacting with the solar wind. hat we see on this object appears to be the same phenomenon wee seen on Jupiter, for example,
reptiles and insects in their colourful sexual displays to attract mates. Source: University of Exete i
and using these to repair their damaged peripheral nerves but this approach has several disadvantages
The finding, in both mouse and human cells, suggests that manipulating a natural process could someday be an alternative way to not just reduce the severity of the flu,
In a series of experiments in mouse and human lung cells, Yount and colleagues showed that inhibiting NEDD4 from doing this job led to an accumulation of IFITM3 in the cells
rather than just relying on traditional chemical screens, says Hubbard, an assistant professor of pharmacology in the University of Alberta Faculty of medicine & Dentistry. ee moving towards a very logical type of treatment for genetic diseases,
While most of the work described in the study was done in mouse models, the researchers also found similar cells in human livers.
Karin team examined three different mouse models of liver cancer. They found no signs of hybrid hepatocytes in any of the tumors,
The authors show that human irisin is similar to the mouse hormone and that it circulates in the range previously reported.
Data from the scans were used to program a 3-D printer that laid down synthetic resins layer by layer.
-D printing has become a regular part of our process, says Smith. t also a tool that allows us to educate our junior colleagues and trainees in a way that safe,
and tapping on our keyboards release energy that largely dissipates, unused. Several years ago, scientists figured out how to capture some of that energy
and expensive mouse avatars that are created by injecting human tumor cells into mice. his is really the first time that it been demonstrated that you can use a rapid methodology like this to spatially define cancer cells and macrophages,
What sets the team model apart from mouse avatars and hard plastic plates is that it can replicate much more accurately the sizes and shapes of the microenvironment within the patient problem area.
Applications of these devices include advanced microscopes, displays, sensors, and cameras that can be mass-produced using the same techniques used to manufacture computer microchips. hese flat lenses will help us to make more compact and robust imaging assemblies,
Manipulating the polarization of light is essential for the operation of advanced microscopes, cameras and displays;
#DNA-Guided 3-D Printing of Human Tissue Is unveiled A UCSF-led team has developed a technique to build tiny models of human tissues, called organoids,
#Mouth Guard Monitors Health Markers, Transmits Information Wirelessly to Smart Phone Engineers at the University of California,
San diego, have developed a mouth guard that can monitor health markers, such as lactate, cortisol and uric acid,
researchers showed that the mouth guard sensor could offer an easy and reliable way to monitor uric acid levels.
In the past, the patient would have needed blood draws to monitor levels and relied instead on symptoms to start
Fabrication and design Wang team created a screen-printed sensor using silver, Prussian blue ink and uricase,
including temporary tattoos that monitor glucose, ultra-miniaturized energy-processing chips and pens filled with high-tech inks for Do it yourself chemical sensors.
At its core, however, is a rule known as Heisenberg uncertainty principle. This states that in any situation in which a particle has linked two properties,
Hayes said. nd it turns out that we have a core mechanism that could be integrated with smartphones
Revealed by a brand new lectron camera, one of the world speediest, this unprecedented level of detail could guide researchers in the development of efficient solar cells, fast and flexible electronics and high-performance chemical catalysts.
Understanding these dynamic ripples could provide crucial clues for the development of next-generation solar cells, electronics and catalysts.
Thin films of Mos2 are also under study as possible catalysts that facilitate chemical reactions. In addition
Now, a team led by Wyss Institute Core Faculty member David Mooney, Ph d.,has developed a new strategy embedding stem cells into porous,
from a genetic mouse model of Alzheimer disease. Then scientists put new technology to its practical application.
The USB-powered sequencer used by Chiu research team, dubbed Minion, was made by Oxford Nanopore technologies
and creating nanoscale spheres made up of platelet membranes with Dox-gel cores. These spheres are treated then
by teaching it to differentiate between species (a yeast cell is different from a mouse).
#Scientists test new gene therapy for vision loss from a mitochondrial disease NIH-funded study shows success in targeting MITOCHONDRIAL DNA in mice Researchers funded by the National institutes of health have developed a novel mouse model for the vision disorder
Their success in creating a mouse model of LHON and using it to test an investigational gene therapy is described today in the Proceedings of the National Academy of Sciences.
This modified virus has been the key to creating a mouse that replicates LHON and to an investigational gene therapy for LHON that is currently in clinical trials.
To create a mouse model for LHON, the researchers loaded the virus with a defective copy of the ND4 gene carrying the same mutation that causes about 70 percent of LHON cases.
Then they injected the virus into fertilized mouse egg cells, and grew the cells to maturity.
the researchers had their mouse model. The presence of the virally encoded ND4 mutation in the eye was confirmed by essentially doing an eye exam to look for the red fluorescent marker.
Prior to development of the new mouse model Dr. Guy lab had shown that they could produce temporary signs of LHON in mice.
The mouse research is helping inform an ongoing NEI-supported clinical trial, which is led by Dr. Guy
says Conor Walsh, Ph d.,Wyss Institute Core Faculty member, Assistant professor of Mechanical and Biomedical engineering AT SEAS, founder of the Harvard Biodesign Lab AT SEAS,
and product development through the partnership with Trajan. he hemapen is an example of ASTECH core foundations;
what they see is a report of the signals depicted in false color on a monitor.
and represent it on a computer screen. In this article, Inserm researchers, using MRI, have succeeded in detecting natural shear waves in the brain using computational techniques borrowed from seismologists
One day when Tripathi was at the Lifespan/Tufts/Brown Center for AIDS Research Retrovirology Core Laboratory to discuss his work,
#New graphene based inks for high-speed manufacturing of printed electronics A low-cost, high-speed method for printing graphene inks using a conventional roll-to-roll printing process,
the first time that graphene has been used for printing on a large-scale commercial printing press at high speed.
who developed the method. eing able to produce conductive inks that could effortlessly be used for printing at a commercial scale at a very high speed will open up all kinds of different applications for graphene
which is in line with commercial production rates for graphics printing, and far faster than earlier prototypes.
it could also initiate entirely new business opportunities for commercial graphics printers, who could diversify into the electronics sector. he UK,
and the Cambridge area in particular, has always been strong in the printing sector, but mostly for graphics printing and packaging, said Hasan,
a Royal Academy of Engineering Research Fellow and a University Lecturer in the Engineering Department. e hope to use this strong local expertise to expand our functional ink platform.
Church is the Robert Winthrop Professor of Genetics at Harvard Medical school and a Wyss core faculty member.
Now University of Pennsylvania researchers have shown at the molecular level how experiencing stress changes a male mouse sperm in such a way that it affects his offspring response to stress.
me that seemingly mild stress to a male mouse would trigger this massive change in microrna response
To find out, the team microinjected the nine mirs into mouse zygotes, which were implanted then into normal female mice who carried them as surrogates.
The result of an NSF award valued at roughly $24 million, including hardware and operating funds,
Dell compute nodes using next-generation Intel Xeon processors, 27 racks of compute nodes totaling 1,
944 nodes or 46,656 cores. 128 gigabytes of dynamic RAM and 320 GB of flash memory per standard compute node. 72 nodes per rack with full bisection Infiniband
Additional GPU and large-memory (1. 5 Terabytes) nodes for applications such as visualization, molecular dynamics simulations,
used in USB drives, SD cards and SSD hard drives. asically, memristors require less energy since they work at lower voltages,
this indicates that the mouse is developing chronic epileptic seizures, says the molecular biologist Prof. Dr. Susanne Schoch from the department of Neuropathology at the University of Bonn.
mouse models were used in this research. Team of scientists took mouse hematopoetic progenitor cellsells that give rise to white blood cells.
especially the mouse model, will be used by academics to isolate healthy cells modified by tumors, and by the pharmaceutical industry in the quest for novel anticancer drugs that block tumor-organ communication,
Kumu founders developed hardware and software that enables a radio receiver to filter out interference from outgoing signals.
and make a high-powered LTE link back to the core network. Making small cells fully wireless should help carriers deploy them in a wider range of places
Mahaffey and his partner in crime (for good) were able to perform any action possible from the car's touchscreen or Tesla's accompanying smartphone app.
and this interference pattern is used for writing/printing holograms. The technique requires far fewer optical components,
But now computer scientists have developed software that automatically screens out low-priority emails or texts. It's called Phylter,
At the moment rumours of the iphone 6s suggest the design will stay the same with big changes coming in the form of the A9 processor
and Force Touch being adapted for the new phone's display y
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