that are shipped as liquids in pods that are placed into the machine prior to each job. the team consists of marcus foley, aaron rowley both biomedical/mechanical engineers and joseph white,
which is known as Stargardt disease. For Kathy, a blind spot takes up the majority of her vision.
and to read him stories at bed time. eing a person with a disability who has two children of her own,
Incredible Technology Our glasses are packed with sophisticated technology designed to support people with legal blindness. esight is hands-free, mobile,
The device uses a method called electro-acupuncture (EAV), a traditional technique for measuring vitamin and mineral levels.
EAV is a form of acupuncture where a small electric current is passed between pairs of electrodes.
it like going to the dentist and having your mouth numbed. It very hard to speak without somatosensory feedback,
#Imec Milab medical game-changer Imec and John Hopkins University of Baltimore have delivered a ame-changer in healthcarewith a chip-based technology called Milab
and blood cells. ilab will bring a revolution in medical diagnostics, says Imec CEO Luc van den Hove,
It replaces expensive medical testing equipment which can take days to deliver results. The technology will be commercialised by a company called Midiagnostics backed by Flemish investors Marc Couke and Michel Akkermans, Flemish investment company PMV and Imec.
am I at risk of heart disease? One day soon your mirror might actually be able to give you the answer.
Facial recognition software looks for telltale markers of stress or anxiety, while the gas sensors take samples of the user breath looking for compounds that give an indication of how much they drink or smoke.
like heart disease or diabetes. revention is the most viable approach to reduce the socioeconomic burden of chronic and widespread diseases,
such as cardiovascular and metabolic diseases, they write. Clinical trials of the device will begin next year at three sites in France
and Italy, aiming to compare its readings with those from traditional medical devices. Facing the consumer Consumer technology that can read signals from the body to interpret underlying physical
and mental health is on the cusp of becoming part of everyday life. For example, Cardiio, originally developed at the Massachusetts institute of technology
This means (cue maniacal laughter) attorneysfees accountantsfees and compliance costs. Raising $50 million under Regulation A is going to require your company to invest money in the process.
He believes cognitive technologies could eventually automate everything from reviewing medical X-rays to commodities trading. he potential goes way beyond automating repetitive tasks,
or complete eradication of all diseases and poverty is up for debate. But the fact is this is going to have an impact bigger than any other impact that man has seen before.
#This MIT Grad Is Changing Medicine With a Needle-Covered Pill While medical injections are unpleasant and inconvenient, theye also necessary for people with illnesses like diabetes.
But that might not be true for too much longer. Carl Schoellhammer, 28, has created a pill that would render syringes unnecessary.
if administered via injection. Although an image of the pill that was used in testing might remind people of a cactus or a porcupine,
freeing the needles to introduce the medicine. Once the drugs are delivered, the capsule can pass through the body safely.
and he hopes to market it as a diagnostic technology that can be used for a wide range of injections such as insulin and growth hormones.
pharmaceutical giant Novartis announced this week that it testing similar technology through a collaboration with a startup called Rani Therapeutics.
a handheld device inserted suppository-style that uses ultrasound waves to push medicine into the tissues of the GI TRACT.
This allows the body to absorb the medicine faster. Schoellhammer sees this being helpful for the 1 million people in the United states who have irritable bowel syndrome (IBS) as well as other conditions.
While he wants to advance the uprobe further and conduct more animal testing, he estimates the product can be on the market in five years.
and his data is sent to his hospital and medical team, if there is any indication of a problem the doctors identify it
and take appropriate action. Mr Youngman says the technology is reassuring: ou have more faith and trust.
Professor Martin Cowie is a Cardiologist ith some patients it very tricky to get the balance right.
The device allows those suffering from heart complaints to remain at home knowing that doctors can keep an eye on them n
#Powerful MRI SCANNERS could predict diseases Cutting-edge technology, designed to delve deeper into the human body, has arrived at a research centre in Portugal.
The ultra-high field MRI SCANNERS are around ten times more powerful than current models. hese new machines will allow scientists to make a very early diagnosis of cancer
In the future, diseases could be predicted in advance. n the normal scanners, the spinal cord is too blurry and we don distinguish too many fine details.
Champalimaud Foundation. here are some very important diseases of the spinal cord, like multiple sclerosis. So when the diseases begin,
there are some microstructural changes in the spinal cord. For example, the diameter of the cell can change,
if the person is going to have a disease or not, or if he is in an early stage.
to carry out comprehensive analysis of some brain diseases, the brain has to be cut and examined after death.
during depression. epression is a widespread disease. It one of the major causes of disability worldwide.
And one of the main problems of depression is that currently there is no way for clinicians to guide a treatment selection,
Potentially in the future it will be useful for clinicians to select treatments and better diagnosis depression. ore precise diagnosis,
and at a faster speed, would make a big difference in medicine. Targeted treatments could come sooner
That upgrade may be a headache but system requirements on Windows haven budged in nine years.
#21st-century medicine: Gauss guns, magic bullets, and magnetic millibot surgeons Sometime around the turn into the 20th century,
medical extraordinaire Paul Ehrlich coined the word zauberkugel or agic bulletto describe new drugs he was working on to cure syphilis and cancer.
In theory, such drugs would leave healthy tissue intact while targeting only the diseased. Psychologists later appropriated this term to describe the phenomenally widespread panic that ensued
when H. G. Well epic 1938 thriller The War of the Worlds was broadcast to an unsuspecting American public.
for example, and would have immediate applications in conditions like hydrocephalus, where proper flow through these chambers is disrupted.
The operators don even sit in the surgical amphitheater, but rather run the show from a separate control room.
remote robotic surgery will have entered a new era. Some time ago, we discussed some of the finer points of installing
#Terapio autonomous medical robot can assist nurses Japan has a rapidly aging population, along with the longest life expectancy in the world.
And while a worldwide shortage of nurses means Japan isn the only country facing this problem,
the country is nonetheless leading the way in developing robots that can assist nurses with the enormous workloads they handle on a daily basis. The latest example is from researchers at Toyohashi University of Technology,
a medical robotic assistant that relieves nurses from some of the mundane tasks of collecting patient data and vital signs.
This allows the nurses to give more personal attention to the patient. Electronic Medical records (EMR) have been implemented in most Japanese medical facilities,
Terapio is programmed to follow a nurse as he or she makes the rounds. There a touch display panel on the top to input collected data straight into the patient EMR.
Terapio can recognize possible allergies and potentially dangerous medication interactions. And naturally, when not displaying data,
rackinglets Terapio automatically follow the nurse around, avoiding any objects or collisions on its own; and ounds,
A camera would allow for remote viewing by the medical staff. Toyohashi University professor Ryosuke Tasaki says,
could make flu shot obsolete Influenza is no longer the scourge it once was thanks to modern medicine,
and specifically, annual vaccination efforts. The flu vaccine isn perfect, though. Influenza mutates rapidly, which means a new vaccine formulation is needed every year.
An international team of researchers has identified a new antibody that might give us the edge in this yearly arms race.
It bypasses the constantly changing surface markers and attacks a different part of the virus membrane.
So why is influenza such a tricky virus to vaccinate against? The virus has a jumble of proteins on its surface called hemagglutinin
and neuraminidase that is uses to enter cells. The pattern of these proteins is different in every strain of influenza,
which allows it to evade your immune system even if youe been infected with the flu before. Basically, you don have antibodies that recognize the new patterns on the virus (known as antigens) until youe encountered the new strain.
When your body has become sensitized to a pathogen, it can prepare an adaptive immune response.
As the immune response picks up, more antibodies are pumped out and other immune cells swing into action to clear virus-infested cells and combat the infection.
A vaccine provides a template of antigens to train the immune response to recognize the new strains of influenza each year.
Doctors have to predict which strains will be most prevalent in the upcoming flu season to formulate the vaccine
This antibody was isolated from the blood of patients infected with the pandemic H1n1 influenza virus in 2009.
and holding them open for a new therapeutic molecule. They could be programmed to grab on to only one sort of marker (say
#India diabetes rate has jumped 123 %since 1990 A global health survey showed that rates of diabetes among Indians has grown at an alarming rate since the early years of the country emergence as a world power.
Between 1990 and 2013, India saw instances of diabetes grow by 123, %with researchers attributing this to the way lifestyles have changed over that time.
The study looked at 301 acute and chronic diseases and injuries in 188 countries, finding that developing nations like India and China are now mimicking a trend that had began earlier in Western nations.
The biggest increase the researchers observed was in Type 2 diabetes the most common form of the disease which is linked most often to obesity.
Endocrinologist Anoop Misra told Times of India that diabetes was an escalating problem in India
and had major socioeconomic dimensions. apid dietary changes coupled with decreased level of physical activity have resulted in increasing obesity and diabetes in rural and semi-urban areas,
Dr Misra said. Diabetes did no feature in the top 10 of India diseases in 1990,
whereas it is the country eighth-biggest killer. Maggi case should begin new era of food vigilancea leading food safety official has urged India government to view the recent Maggi noodles affair as the beginning of a new era of food safety vigilance.
Thuppil Venkatesh a senior government advisor and expert in lead poisoning, said the ublic clamourthat followed after a state testing allegedly found monosodium glutamate
and lead in Maggi noodles should initiate a campaign against unhealthy food in general. He also called for greater self-regulation by manufacturers and better awareness among the public about how much food safety testing takes place behind the scenes. he heated discussion on the presence of lead in food products,
In medicine you talk of drug delivery-we do flavour delivery."."The sensory profile of Douxmatok is literally the same as sugar."
At the same time, however, the mechanical stress on the products needs to be kept as low as possible,
and stress signals that is otherwise invisible to the human eye. The crop health monitoring imagery utilized by Farmlogs shows information that is actionable
and added that it has found no evidence that that medical information such as insurance claims and test results was targeted
identity or medical and financial fraud, explained Rob Sadowski, director of technology solutions at security specialist RSA,
from oncological research to education. This latest collaboration makes Watson somewhat more tangible to the average person,
to help oncologists find targeted diagnoses. In each of these cases, Watson reads and understands more and more of the published literature
If an individual has a condition like celiac disease Chef Watson can pull up gluten free recipes. While superficially, the app can be used to create interesting, delicious dishes,
and work with prior to surgery, according to the researchers. GHOST researchers are also working with sponges
may one day be used to treat pain, depression, epilepsy, and other neurological disorders in people by targeting therapies to specific brain circuits.
Published online in the journal Cell, the research is a major step forward in pharmacology and builds on earlier work in optogenetics,
it should be possible to manufacture therapeutic drugs that could be activated with light, says co-principal investigator Michael R. Bruchas, associate professor of anesthesiology and neurobiology at Washington University in St louis. ith one of these tiny devices implanted,
we could theoretically deliver a drug to a specific brain region and activate that drug with light as needed.
This approach potentially could deliver therapies that are targeted much more but have fewer side effects. Previous attempts to deliver drugs or other agents
RESS OF A BUTTONOW, we literally can deliver drug therapy with the press of a button,
marijuana use has risen in past decadesarticularly among black teens. ur analysis shows that public health campaigns are workingewer teens are smoking cigarettes,
a long-term ongoing epidemiological study conducted by the University of Michigan. Lanza and her team focused on information reported about the rates of use of three different substanceslcohol, cigarettes,
The National Institute on Drug abuse and the National Cancer Institute supported this work r
#Tiny laresshow when RNA goes off track A new technology called ticky-flaresoffers the first real-time method to track
such as mental disability, autism, and cancer. Sticky-flares have the potential to help scientists understand the complexities of RNA better than any analytical technique to date
and observe and study the biological and medical significance of RNA misregulation. Previous technologies made it possible to attain static snapshots of RNA location
Mirkin is professor of chemistry in the Weinberg College of Arts and Sciences and professor of medicine, chemical and biological engineering, biomedical engineering and materials science and engineering.
which was the first genetic-based approach that is able to detect live circulating tumor cells out of the complex matrix that is human blood.
The National Institute of Arthritis and Musculoskeletal and Skin diseases and the Center for Cancer Nanotechnology Excellence initiative of the National institutes of health supported the work.
For example, the damage from a major heart attack could cost you around five billion heart cells. Future stem cell treatments will require this number
professor of biomedical surfaces at University of Nottingham. hat we are doing here is paving the way for the manufacture of stem cells in large numbers
when those therapies are proved to be safe and effective. sing a high throughput materials discovery approach,
#Pair of compounds could hockhiv Highly active anti-retroviral therapy (HAART) has helped millions of people survive HIV.
The study appears in PLOS Pathogens. e are excited to have identified an outstanding candidate for HIV reactivation
Davis. his molecule has great potential to advance into translational and clinical studies. hile HAART has been quite successfuleducing HIV infection in newborns,
and lowering viral loads to virtually undetectable levelshese therapies cannot cure the disease alone. Once treatment is discontinued,
and the infection comes roaring back. As a result, patients must remain on treatment indefinitely,
which will go a long way toward clearing the virus. She also believes HIV vaccines in development could give patients an extra edge.
Even a vaccine that isn 100 percent effective at preventing transmission could boost a patient ability to destroy reactivated virus. However,
When disease-causing bacteria invade disease-resistant rice, a small protein produced by the bacteria betrays the invader.
and mounts an immune response to fend off infection, researchers report. Identification of the tiny protein, called Raxx, holds promise for developing more disease-resistant crop varieties and therapeutic treatments for blocking microbial infections in both plants and animals, say the researchers,
who found particular satisfaction in this discovery, two years after retracting the announcement of a similar find.
Disease protection for our food In this new study researchers discovered that the Raxx protein was present in at least eight species of the disease-causing Xanthamonas bacteria that are known to attack ricehe staple food for half of the world populations well as maize, cassava, sugar cane, tomatoes, peppers
, wheat, alfalfa, onions, banana, and citrus. ur research team is delighted to announce the discovery of the Raxx protein,
Ronald notes that her laboratory is currently investigating the role of Raxx during bacterial infection of rice in the absence of the immune receptor.
In the long term, the researchers hope to use this information to develop new strategies to prevent infection in various crops.
and disease resistance for more than two decades and in 1995 announced that a gene called Xa21 confers resistance to the bacterial blight pathogen.
and sparked further research into other key parts of the disease-resistance puzzle. Researchers were confident that
#Rare case uncovers missing clue to Fragile X Fragile X syndrome may not only be a problem of receivers in the brain letting in too much information.
In patients with fragile Xhe most common cause of inherited intellectual disability key gene is disabled completely
which eliminates a protein that regulates electrical signals in the brain and causes a host of behavioral, neurological,
GENE NEW ROLE In contrast, the patient in the new study has only a single error in the gene and exhibits only two classic traits of fragile Xntellectual disability and seizures.
GENETIC ERROR Fragile X syndrome results from an inherited genetic error in a gene called FMR1.
so the syndrome affects males more often and more severely than females, who may be able to compensate for the genetic error
One of the mysteries of the syndrome is how loss of a single gene can lead to such a variety of effects in different patients.
anxiety, and impulsive behavior. Typical physical symptoms include enlarged heads, flat feet and distinctive facial features.
Almost one-third of patients with fragile X also show symptoms of autism spectrum disorders.
the researchers genetic sequencing data from more than 900 males with intellectual disabilities but without classic fragile X syndrome.
although this individual has intellectual disability and seizures, his physical features are not typical of the syndrome,
and he is not autistic. To see what effect this mutation might have, geneticist Stephen T. Warren and colleagues at Emory University replicated it in mouse brain cells
who is also an associate professor of biomedical engineering. his patient presents a case of partial fragile X syndrome associated with mutated, rather than absent, FMRP.
researchers were able to verify the same effect from just the mutation and link it to human disease.
#Bacteria build#coat#for medical implants Artificial implants, like pacemakers, can spark the body defenses and cause complications, even rejection.
or coat medical implants in 3d micro-structures, which can make the implants more biocompatible.
Researchers had discovered already that cells interact better with rough or structured surfaces than with smooth ones and can cling to them more effectively.
Until now, however, it hasn been possible to apply these surface structures to one of the most promising materials in the field of medicine:
Skin cells could grow over a wound more effectively if they moved in accordance with structured cellulose.
but also help to minimize the body rejection reaction to an artificial implant. In studies using mice
and can cause complications. ur aim is for artificial implants to be accepted by the patient body without inflammation
which could make it easier to pinpoint the causes of cancer. In many cases, genetic mutations that cause cancer involve chemical changes to individual building blocks of DNAREATING DNA ADDUCTS."
"Natural products can be a source of effective cancer drugs, and several are being used for treating a variety of cancers,
"Gavin Robertson says.""Over 60 percent of anticancer agents are derived from plants, animals, marine sources, or microorganisms.
a professor of food and nutrition toxicology at ETH Zurich, has succeeded for the first time in amplifying gene samples containing DNA ADDUCTS
it may therefore be possible to expand DNA sequencing from the four basic DNA building blocks to include adducts. he scientific community would have an important tool for making a detailed analysis of the molecular mechanisms involved in the initiation of cancer
#Donor tissue for joint repair stays fresh for 60 days Currently doctors have to throw away more than 80 percent of donated tissue used for joint replacements
a professor of orthopedic surgery at the University of Missouri School of medicine. he benefit to patients is that more graft material will be available
This will allow us as surgeons to provide a more natural joint repair option for our patients.
donated tissues are stored within a medical-grade refrigeration unit in sealed bags filled with a standard preservation solution.
says study coauthor James Cook, director of the Comparative Orthopedic Laboratory and the Missouri Orthopedic Institute Division of Research. ith the traditional preservation approach,
schedule surgery and get the graft to the surgeon for implantation. METAL IMPLANTS VS. TISSUE GRAFTS Stannard says that patients with metal and plastic implants often are forced to give up many of the activities they previously enjoyed
in order to extend the life of their new mechanical joints . or patients with joint problems caused by degenerative conditions,
metal and plastic implants are still a very good option, Stannard adds. hen the end of a bone that forms a joint is destroyed over time,
the damage is often too extensive to use tissue grafts. owever, for patients who experience trauma to a joint that was otherwise healthy before the injury,
previous activity levels needn be altered drastically if we can replace the damaged area with living tissue.
However, the method of preserving the grafts themselves has limited the amounts of quality donor tissue available to surgeons. 100%USABLE AT 60 DAYS Additionally, because of testing requirements and logistics,
Anopheles gambiae, a major malaria vector, is isolated interbreeding with pockets of another malaria mosquito, A. coluzzii. Entomologists initially considered them as the
says medical entomologist Gregory Lanzaro, professor in the pathology, microbiology and immunology department at University of California,
The World health organization World Malaria Report indicates that deaths from malaria worldwide have decreased by 47 percent since 2000.
Now there n urgent need to develop new and effective malaria vector control strategies, Lanzaro says.
#High-res MRI links cerebellum to bipolar disorder A different type of MRI has given researchers an unprecedented look at previously unrecognized differences in the brains of people with bipolar disorder, a new study reports.
The cerebellar differences were not present in patients taking lithium, the most commonly used treatment for bipolar disorder.
professor of psychiatry at University of Iowa. o it really providing a new picture and new insight into the composition and function of the brain in bipolar disease.
Despite being relatively commonipolar disorder affects about one percent of the populationcientists don have a good understanding of what causes bipolar disorder,
Researchers examined 15 patients with bipolar disorder and 25 control subjects matched for age and gender.
ELEVATED MRI SIGNAL Compared to the brains of people without bipolar disorder, the MRI signal was elevated in the cerebral white matter
and the cerebellar region of patients affected by bipolar disorder. The elevated signal may be due to either a reduction in ph or a reduction in glucose concentrationoth factors influenced by cell metabolism.
Previous research has suggested that abnormal cell metabolism may play a role in bipolar disorder. However, investigating metabolic abnormalities in the brain has been hindered by lack of a good imaging tools.
Available methods are slow low-resolution, and require researchers to identify the region of interest at the beginning of the study.
The study is the first time this MRI technique has been used to investigate a psychiatric disease. One reason researchers didn know that the cerebellum might be important in bipolar disorder,
is because no one chose to look there, says Casey Johnson, postdoctoral researcher and first author on the study that is published in the journal Molecular Psychiatry. ur study was essentially exploratory.
We didn know what we would find. The majority of bipolar disorder research has found differences in the frontal region of the brain.
We found focal differences in the cerebellum, which is a region that hasn really been highlighted in the bipolar literature before."
and go to a doctor, aggregation already has a stronghold in their brains, "says Lisa Lapidus,
and other diseases that involve neurotoxic aggregation. MRI probe detects Alzheimer's at earliest stage Spurred on by the finding,
the researchers conducted an extensive search of the scientific literature on bipolar disorder and began to find pieces of evidence that suggested that the cerebellum may function abnormally in bipolar disorder
and that lithium might potentially target the cerebellum and alter glucose levels in this brain region. ur paper,
The researchers hope that the new insights provided by the T1 rho imaging might help refine understanding of the abnormalities that underlie bipolar disease
While lithium can be an effective mood stabilizer for people with bipolar disorder, it causes numerous unpleasant side effects for patients. f lithium effect on the cerebellum is the key to its effectiveness as a mood stabilizer,
then a more targeted treatment that causes the same change in the cerebellum without affecting other systems might be a better treatment for patients with bipolar disorder,
and the National Alliance for Research on Schizophrenia and Depression provided funding for the study.
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