and an expert in nanoengineering for health care and medical applications. hen you think about field deployment,
Projects run the gamut from health care and public safety to education and entrepreneurship. A project in India is helping to educate migrant children.
That same amount of money could provide them more permanent housing, comprehensive health care and employment services.""A considerable amount of public dollars is spent essentially maintaining people in a state of homelessness,"Dennis Culhane,
The formerly homeless can get mental health treatment counseling or other services to help them overcome their demons,
our health care to be patient-centric and our education to be student-centric, "O'sullivan explains of the growing market opportunity."
their treatment options are limited to antibiotics, blood transfusions, and fluid supplements to deal with the symptoms of the disease.
Citizens Health care Working group (CHCWG:##Under the direction of Health and human services, CHCWG commissioned by Congress to enlist citizens to provide input to review health care system.
and Case Western Reserve's work applying high-definition multipoint video conferencing to telemedicine. Sue Spradley also pointed out that U s. Ignite is seeking not only to incubate new applications
As next-generation genome sequencing heads into the clinic and public health, it ll be targeted at people who don t necessarily fully understand these issues.
Basically, that inhibits the ability to do good public health analyses of bacterial genomes. The work was published in Nature Biotechnology this week.
the Obama Administration has been pushing EHRS as the solution to all that ails health care. The idea is that the data they collect can drive change,
The information can also be used to prove to insurers that the money they spend on health care is producing results. ealth care providers are more and more being paid for outcomes,
a care management platform designed to help low-income Utah residents suffering from mental health issues.
Utah Smartcare partners with three local mental health authorities and 2 community health clinics in Utah.
one of the local mental health authorities participating in the Utah Smartcare initiative. his data will allow us to better assess how our clients are doing between appointments
#It s the most ubiquitous medical device in the world and we re simply piggybacking off of and improving regular behavior.#
The Kinsa costs $29. 99 and alongside hardware sales the company is considering how they can be a communications layer for other companies working on telemedicine prescription delivery and other startups in the health ecosystem.
Lin says. e fit in as part of that first step into telemedicine. Like Scanadu devices, the Clinicloud medical kit hooks information from the app up with remote physicians.
but could expand to include other telemedicine services in the future. The other thing to keep in mind about the kit is the price.
#Benefits to medical device manufacturers include cost savings through not having to develop a completely new device leveraging existing platforms
or act as accessories to existing medical devices and allow the smartphone to act as a##dumb-user interface
Addressing Two Critical Questionssagentia believes there are two critical questions for medical device companies entering this space:
and incorporate it into a medical device? And equally important how do you make money from doing so?
MMAS should be treated like any other medical device. Risk analysis is key and careful system design will ensure that safety critical functions are implemented appropriately.
Once companies decide to incorporate an MMA they follow the same type of development roadmap used for any other medical device.
development under the ISO 13485 medical device standard.####As an example of how to manage the risks of including apps in connected systems Tighe cites the Verihaler which Sagentia has developed to monitor patient adherence to treatment for asthma or chronic obstructive pulmonary disease (COPD.
With such great opportunities available it s no surprise that many medical device companies have connected health on their agendas.
#Benefits to medical device manufacturers include cost savings through not having to develop a completely new device leveraging existing platforms
or act as accessories to existing medical devices and allow the smartphone to act as a##dumb-user interface
Addressing Two Critical Questionssagentia believes there are two critical questions for medical device companies entering this space:
and incorporate it into a medical device? And equally important how do you make money from doing so?
MMAS should be treated like any other medical device. Risk analysis is key and careful system design will ensure that safety critical functions are implemented appropriately.
Once companies decide to incorporate an MMA they follow the same type of development roadmap used for any other medical device.
development under the ISO 13485 medical device standard.####As an example of how to manage the risks of including apps in connected systems Tighe cites the Verihaler which Sagentia has developed to monitor patient adherence to treatment for asthma or chronic obstructive pulmonary disease (COPD.
With such great opportunities available it s no surprise that many medical device companies have connected health on their agendas.
#Fingerprinting Infants Helps Track Vaccinations in Developing Countries Billions of dollars a year are spent vaccinating children in developing countries
but about half as many immunizations are administered as could be because of unreliable vaccination records. Biometric researchers from Michigan State university have developed a fingerprint-scanning system for children under five years old that could replace ineffective paper vaccination records.
Until now biometrics experts believed fingerprints of babies and toddlers were too unreliable because image sensors are designed for the ridges and valleys of adult fingertips.
Paper-based vaccination records are lost easily and don t reliably provide health workers with up-to-date information on patient history.
The Bill and Melinda Gates Foundation funded the research specifically for recording vaccinations but the patient-identifying system has broader applications says Anil Jain a distinguished professor at Michigan State university s Computer science and Engineering Department and coauthor of the paper.
and death certificates to health care records school enrollments and voter registration. The Michigan State university researchers needed to process images taken from fingerprint sensors using software to compensate for the small size of the children s fingerprints as well as their sometimes wet and oily skin.
Compared to the status quo of not getting vaccinations for life-threatening diseases mothers are not asking these questions
Nonetheless Poon says that is sufficient for this kind of low-power medical device. It also met safety regulations limiting the amount of radiation delivered to a given amount of tissue in humans.
can big data make health care better? here is a lot of data being gathered. That not enough, says Ed Martin,
and the challenges they will face as they push to remake health care. The groups that control the most medical data today are insurance companies and care providers,
and their data analysis is already beginning to change health care. Express Scripts which manages pharmacy benefits for 90 million members in the U s
and hopes to sell them to manufacturers of wearable electronics, medical devices, smart labels, and environmental sensors.
While gene drives may have commercial and public health uses, 10 scientists published an editorial today in the journal Science calling for more public discussion,
Companies including the medical device giant Medtronic and startup Cortera Neurotechnologies a spin out from UC Berkeley wireless laboratory,
These findings lead to the potential of moving from vaccines for specific influenza strains towards developing a protection,
"Our extraordinary breakthrough could lead to the development of a vaccine component that can protect against all new influenza viruses, with the potential for future development of a one-off universal flu vaccine shot,
either through infection or through vaccination. The study was published in the journal Science e
#Now, aircraft wings that can'self heal'on the fly Even the researchers involved in the project describe it as"verging on science fiction".
#This vaccine could help block HIV WASHINGTON: Scientists have designed a new experimental HIV vaccine that may stimulate the immune system to block infection from the deadly virus. New research led by scientists at The Scripps Research Institute (TSRI),
INTERNATIONAL AIDS Vaccine Initiative (IAVI) and the Rockefeller University shows in mice that the vaccine candidate can stimulate the immune system activity necessary to stop HIV infection.
The findings could provide key information for the development of an effective AIDS vaccine, researchers said.
The research, published in the journals Cell and Science, represents a leap forward in the effort to develop a vaccine against HIV
which has struggled so far to elicit antibodies (immune system molecules) that can effectively fight off different strains of the virus."The results are said pretty spectacular
While many vaccines for other diseases use a dead or inactive version of the disease-causing microbe itself to trigger antibody production,
This challenge has led researchers to believe that a successful AIDS vaccine will need a series of related
"The vaccine appears to work well in our mouse model to'prime'the antibody response,
while posing a greater threat to public health. The study is the first to demonstrate how leptospira mutates to form a biofilm, an extra protective layer of microbial cells,
The mutation study, published in a Federation of European Microbiological Studies journal in May, was a wake-up call for public health experts to find better ways to tame the bacteria.
or vaccinating animals.""Till that happens, early diagnosis and prompt treatment is the key
#Vaccine success holds hope for end to deadly scourge of Ebola The world is for the first time on the verge of being able to protect humans against Ebola,
the World health organization (WHO) said on Friday, as data from a trial in Guinea showed a vaccine was 100 percent effective.
Initial results from the trial, which tested Merck and Newlink Genetics'VSV-ZEBOV vaccine on some 4, 000 people who had been in close contact with a confirmed Ebola case,
showed 100 percent protection after 10 days. The results were described as"remarkable"and"game changing"by global health specialists."
"We believe that the world is on the verge of an efficacious Ebola vaccine, "WHO vaccine expert Marie Paule Kieny told reporters in a briefing from Geneva.
The vaccine could now be used to help end the worst recorded outbreak of Ebola, which has killed more than 11,200 people in West Africa
since it began in December 2013. WHO Director-General Margaret Chan said the results, published online in the medical journal The Lancet,
"This and other vaccine trials were tracked fast with enormous international effort as researchers raced to be able to test potential therapies
and vaccines while the virus was still circulating.""We knew it was a race against time
"says John-Arne Rottingen, head of infectious disease control at the Norwegian Institute of Public health and chair of the trial's steering group."
"Ring vaccination"The Guinea trial began on March 23 to evaluate the effectiveness and safety of a single dose of VSV-ZEBOV using a so-called"ring vaccination"strategy,
where close contacts of a person diagnosed with Ebola are immunised-either immediately, or at a later date.
As data began to emerge showing the very high protection rates in those vaccinated immediately,
with all participants receiving the vaccine immediately, and will be extended to include 13-to 17-year-olds and possibly also 6-to 12-year-old children,
which allowed the team in Guinea to assess this vaccine in the middle of an epidemic"."""Our hope is that this vaccine will now help bring this epidemic to an end
and be available for the inevitable future Ebola epidemics, "his statement said. The medical charity Doctors without Borders (MSF),
whom had feared that a sharp decline in cases this year would scupper hopes of proving that a vaccine could work.
as the only real hope for demonstrating the efficacy of a vaccine e
#China plans to enforce real names on Social media Chinese government has issued new regulations to eliminate fake social media accounts.
#Japan to invest $21 million in developing 3d printed human organs Could 3d printable human organ transplants become a reality in the coming years?
Recently, additive manufacturing played a significant role in the development of a revolutionary new medical device that,
as an estimated 21 people waiting for organ transplants are dying every single day. And this is exactly where CELLINK comes In this Swedish company lead by Erik Gatenholm
At age 18, Erik Gatenholm started his first medical device company, manufacturing meniscus implants and other implants, such surgical meshes for ventral hernia repairs and wound dressings.
they have grown out to become a global leader in the field of implantable medical devices, and the Redura is just one of the many products they have released.
he said. he plan is to develop more than 10 kinds of implantable medical devices products within the next 5 years.
and vaccination tracking campaigns in resource-poor and field settings. In addition to serving low-resource or remote areas, the researchers noted that intrinsic wireless connectivity can serve epidemic-related studies,
with low-cost prosthetics acting as a clear example of just how personal and affordable medical devices can be.
or tracking vaccination campaigns in most resource-poor settings. It fantastic for an undergrad to be first author on the publication.
which is still the gold standard in the health care industry for making a definitive diagnosis. Also routinely used today is a newer method for rapidly identifying bacteria based on a DNA-analysis technique called quantitative polymerase chain reaction (qpcr),
and is registered FDA as a Class 1 medical device in the U s a CE mark in the EU
Thanks to this, the article published today in PLOS ONE describes a new step towards the creation of a vaccine,
This technique could be a much better candidate for a human vaccine. The invention is protected commercially
to start clinical trials on human candidates for preventive vaccination and to cure the disease by combining the vaccine with regenerative therapies.
The Germans Trias Institute plans to carry out these steps with patients at the hospital and to optimize the product by dosage and guideline studies.
which is why the chances of developing an effective vaccine have been deemed low.)They show that this new formulation reduces the minimal curative dose in a disease model, based on infections in mice, by 100-fold and,
and Innovation and plans to conclude the Clinical Research regulated by the Federal Commission for Protection Against Health risks (COFEPRIS) next year.
to $289 billion annually in unnecessary health care costs from additional hospital visits and other issues.
Technology areas of interest include cloud applications, analytics, social media, mobile, materials, medical devices, digital health, healthcare IT, instruments and cloud software infrastructure.
and heavy metals, will revolutionize medical device industry. s
#Novel Method Utilizes Nanoparticles and UV LIGHT to Isolate, Extract Contaminants In a new paper published this week in Nature Communications,
and an expert in nanoengineering for health care and medical applications. hen you think about field deployment,
In particular wearable vital sign monitoring devices is set to revolutionize the healthcare and medical devices industry over the next few years.
and medical devices said Ching-Yen Tsay Chairman of ITRI. This reflective pulse oximetry sensor is just the beginning of a line of wearable solutions that Taiwan Biophotonic Co. will be introducing this year.
Concerned about these alarming statistics, experts at the Johns Hopkins Bloomberg School of Public health Center for Injury Research and Policy challenged a team of Johns Hopkins undergraduate mechanical engineers to design
said Kavi Bhalla, assistant professor at the university Bloomberg School of Public health and one of the team mentors for the project.
Andrea Gielen, director of the Johns Hopkins Center for Injury Research and Policy at the Bloomberg School of Public health and one of the team mentors, said she
which aims to bring new drugs and medical devices to patients. Cathy Yelf, of the Macular Society, said:"
#Scientists find molecular switch that creates long-term immunity Melbourne researchers have identified a protein responsible for preserving the antibody-producing cells that lead to long-term immunity after infection or vaccination.
""The hope for a definitive cure and an effective vaccine has been frustrated by HIV's endless propensity to subvert the host's defences
A team of scientists at Johns Hopkins Bloomberg School of Public health now find that a Kupffer cell protein called CD68 is needed for parasite passage and efficient liver infection,
and enable telemedicine and mobile health, but there also another angle that makes them attractive,
170 cases of the virus worldwide and about 480 of the patients have died, according to the European Center for Disease prevention and Control.
#MERS Not Given Same Vaccine Attention as Ebola, Other Viruses A MERS outbreak has infected about 150 people in South korea,
But a vaccine is not among their tools since it doesn yet exist, and is probably not close to being developed.
has no vaccine, according to the Centers for Disease Control and Prevention. MERS was discovered only in 2012 in Saudi arabia.
However, fewer companies have worked on vaccines and drugs for the MERS virus, according to Reuters. Small biotech companies such as Greffex,
Inovio and Novavax have done all some investigation on vaccines for the sickness but the research is still all preclinical,
Ebola research, including vaccines and treatments, dominated headlines worldwide in the wake of the outbreak of the virus in multiple West african nations last year.
000 doses of its Phase I trial vaccine in Africa. However, other viruses were also acingfor deployment amid the panicked fears as that outbreak spread.
The SARS vaccine work proceeded for years but since the virus mostly disappeared, there are not enough live examples of disease to effectively test it, according to multiple reports.
to $289 billion annually in unnecessary health care costs from additional hospital visits and other issues.
said Michael Salter, M d.,Ph d.,Head and Senior Scientist, Neuroscience & Mental health at Sickkids and Professor at The University of Toronto,
'"Smartphone apps are the latest tools to emerge from the intersection of health care and Silicon valley,
#Could Dissolvable Microneedles Replace Injected Vaccines? Osaka University Study Eric is terrified. He stands outside the clinic and takes a few deep breaths before walking slowly through the automatic doors.
and studies suggest that around 1 in 12 people cite fear as their reason for not getting vaccinated.
A new vaccine delivery system could solve this problem: dissolvable microneedle patches are simple to use, pain-free and effective.
Flu vaccines delivered using microneedles that dissolve in the skin can protect people against infection even better than the standard needle-delivered vaccine,
The authors of the study, from Osaka University in Japan, say their dissolvable patch the only vaccination system of its kind could make vaccination easier, safer and less painful.
Downsizing to address the needle problem Most vaccines are injected under the skin or into the muscle using needles.
often causing them to avoid vaccination. The new microneedle patch is made of dissolvable material, eliminating needle-related risks.
where healthcare resources are limited. ur novel transcutaneous vaccination using a dissolving microneedle patch is the only application vaccination system that is readily adaptable for widespread practical use,
we believe it will be particularly effective in supporting vaccination in developing countries. The new microneedle patch Microhyala is dissolvable in water.
taking the vaccine with them. The researchers compared the new system to traditional needle delivery by vaccinating two groups of people against three strains of influenza:
A/H1n1, A/H3n2 and B. None of the subjects had a bad reaction to the vaccine,
people given the vaccine using the microneedles had an immune reaction that was equal to or stronger than those given the vaccine by injection. e were excited to see that our new microneedle patch is
just as effective as the needle-delivered flu vaccines, and in some cases even more effective, said Dr. Nakagawa. e have shown that the patch is safe and that it works well.
Since it is also painless and very easy for non-trained people to use, we think it could bring about a major change in the way we administer vaccines globally.
New approaches to vaccination According to the World health organization immunization prevents an estimated 2 million to 3 million deaths every year.
The continued threat of pandemics such as H1n1 swine flu and emerging infectious diseases such as Ebola makes vaccine development and mass vaccination a priority for global healthcare.
Delivery methods that do not require needles are safer for the person administering the vaccine,
more pleasant for the person receiving the vaccine, and potentially less expensive. The challenge is developing a delivery method that gets the vaccine into the body effectively.
Microneedles provide one such delivery method, and they can be made of various different materials. Previous research has evaluated the use of microneedles made of silicon or metal
but they were shown not to be safe. Microneedles made from these materials also run the risk of breaking off in the skin, leaving tiny fragments behind;
For some diseases, vaccines may be more effective when theye absorbed through the mucous membranes in the nose.
For example, studies in mice have suggested that tuberculosis vaccines delivered through the noseare more effective than those that are injected,
either alone or as an adjunct to traditional parenteral methods of vaccine administration. e
#Bionic Hand Uses Smart Wires To Mimic Muscle fibers, Study Engineers in Germany have built a biologically inspired artificial hand with muscles made from bundles of'smart'wires.
or tracking vaccination campaigns in most resource-poor settings. It fantastic for an undergrad to be first author on the publication.
A single vaccine that immunizes against all types of influenza may soon be a reality,
Researchers said that the breakthrough could lead to the development of a vaccine that can fight all new influenza viruses. Professor Xu,
China, said this study would significantly enlighten T-cell based vaccine development and immune intervention during severe influenza infection in the future.
as a result of collaboration between Kobe-based medical device manufacturer My Tech researchers from Showa University uses a biochip,
Vaccination will no longer be a painful process as researchers from Japan's Osaka University have developed a new technique that can deliver vaccines without needles.
The new method will encourage vaccination thus aiding in reducing global disease burden. The technique was found to be safe and effective in lab testssingapore:
Vaccination will no longer be a painful process as researchers from Japan's Osaka University have developed a new technique that can deliver vaccines without needles.
The new method will encourage vaccination thus aiding in reducing global disease burden. Through this technology, vaccines are delivered simply by laying a tiny patch onto a person's finger,
before it dissolves into their skin.""We were excited to see that our new microneedle patch is
just as effective as the needle-delivered flu vaccines, and in some cases even more effective,"said Professor Nakagawa, one of the authors of the Osaka University study.
linical study and stability assessment of a novel transcutaneous influenza vaccination using a dissolving microneedle patch,
#Approval for AIDS Vaccine at Canadian University The Food and Drug Administration has given Canadian researchers approval to test a vaccine for HIV/AIDS on humans.
a vaccine could be on the market in about five years. Similar to the approaches used to develop vaccines for polio, influenza, rabies and Hepatitis a,
the vaccine is the first based on a genetically modified, killed whole virus and is the only HIV vaccine currently under development in Canada,
and one of the only few in the world. Beginning next month a clinical trial on 40 HIV-positive volunteers will begin.
Following the trials, tests will begin on 6, 600 HIV-negative but high-risk category volunteers.
These tests will focus on immune responses and effectiveness of the vaccine in two more phases s
This is why Boston Children is convening top thought leaders to address the toughest challenges in pediatric health care today.
and health care policy to engage in discussions collectively taking on problems that no single organization can solve alone.
Two patients with beta-thalassemia, a genetic disorder which normally requires regular blood transfusions, have been able to forgo transfusions for at least five months following a gene therapy treatment from bluebird.
His endeavor aims to make medical devices both affordable and available to the masses. The way Prakash sees it
"'Smartphone apps are the latest tools to emerge from the intersection of health care and Silicon valley,
and could turn Google maps into platform for mapping environmental air quality against public health standards. Google street view Maps Urban Air pollution Like Never Before Aclima equipped three Google street view vehicles for the Denver pilot program for a month-long system test during the DISCOVER-AQ study conducted by NASA and EPA.
or exceeds public health standards. While EPA monitoring network is designed to inform air quality regulation, it was unable to provide street-level air measurements until now. nvironmental air quality is an issue that affects everyone,
It's another example of the miracles 3d printing is bringing to health care and if it isn't enough to give you all of the feels we don't know what will.
The U-turn, based on a report by the committee, will undo almost 40 years of public health warnings about eating food laden with cholesterol.
and Italy, aiming to compare its readings with those from traditional medical devices. Facing the consumer Consumer technology that can read signals from the body to interpret underlying physical
and mental health is on the cusp of becoming part of everyday life. For example, Cardiio, originally developed at the Massachusetts institute of technology
and specifically, annual vaccination efforts. The flu vaccine isn perfect, though. Influenza mutates rapidly, which means a new vaccine formulation is needed every year.
An international team of researchers has identified a new antibody that might give us the edge in this yearly arms race.
It bypasses the constantly changing surface markers and attacks a different part of the virus membrane.
So why is influenza such a tricky virus to vaccinate against? The virus has a jumble of proteins on its surface called hemagglutinin
A vaccine provides a template of antigens to train the immune response to recognize the new strains of influenza each year.
Doctors have to predict which strains will be most prevalent in the upcoming flu season to formulate the vaccine
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