#Could dissolvable microneedles replace injected vaccines? The microneedle patch can dissolve in the skin, delivering the flu vaccine painlessly.
New vaccine patch protects against flu in humansflu vaccines delivered using microneedles that dissolve in the skin can protect people against infection even better than the standard needle-delivered vaccine,
according to new research published in Biomaterials. The authors of the study, from Osaka University in Japan, say their dissolvable patch the only vaccination system of its kind could make vaccination easier, safer and less painful.
According to the World health organization, immunization prevents an estimated 2-3 million deaths every year. The continued threat of pandemics such as H1n1 swine flu and emerging infectious diseases such as Ebola makes vaccine development and mass vaccination a priority for global healthcare.
Most vaccines are injected under the skin or into the muscle using needles. While this is an effective delivery method,
it requires medical personnel with technical skills and brings the risk of needle-related diseases and injuries.
where healthcare resources are limited. ur novel transcutaneous vaccination using a dissolving microneedle patch is the only application vaccination system that is readily adaptable for widespread practical use,
we believe it will be particularly effective in supporting vaccination in developing countries. he new microneedle patch Microhyala is dissolvable in water.
taking the vaccine with them. The researchers compared the new system to traditional needle delivery by vaccinating two groups of people against three strains of influenza:
A/H1n1, A/H3n2 and B. None of the subjects had a bad reaction to the vaccine,
people given the vaccine using the microneedles had an immune reaction that was equal to or stronger than those given the vaccine by injection. e were excited to see that our new microneedle patch is
just as effective as the needle-delivered flu vaccines, and in some cases even more effective, said Professor Nakagawa.
Previous research has evaluated the use of microneedles made of silicon or metal, but they were shown not to be safe.
we think it could bring about a major change in the way we administer vaccines globally, said Professor Nakagawa.
and an effective vaccine has been frustrated by HIV endless propensity to subvert the host defences and persist in small populations of long-lasting reservoirs despite antiretroviral therapy,
New knowledge should also help with using adenoviruses in vaccination and gene therapy e
#Scientists discover first NA ambulanceu of T researchers have discovered how severely damaged DNA is transported within a cell
#New material opens possibilities for super-long-acting pills Medical devices designed to reside in the stomach have a variety of applications,
and deliver drugs and vaccines, a olar spongethat can capture and release carbon dioxide emissions andplastic material that gets better with age.
and the simplicity of its use could make it suitable for first aid at home. anticipate that in the future,
#Synchrotron shines a light on future medical devices According to the international team, this technique could be important in the development of devices that are highly sensitive to magnetic fields,
#World's first malaria vaccine gets green light from European regulatory agency The world's first malaria vaccine has cleared its last major hurdle on its way to being approved for real-world use.
The European Medicines Agency (EMA) the regulatory group in the European union which roughly parallels the FDA gave a positive opinion of the vaccine,
The vaccine RTS S, also called Mosquirix, is the product of British pharmaceutical company Glaxosmithkline and is funded partly by the Bill and Melinda Gates Foundation.
It's not the only vaccine developed to fight malaria; an experimental malaria vaccine called Pfspz was found to be much more effective at preventing malaria infection.
Yet Mosquirix is the first to make it this far along in the approval process. Mosquirix helps to prevent infection from the Plasmodium falciparum, one of the deadlier malaria parasites.
The vaccine prompts the body to produce a higher amount of antibodies to stop the parasite from infecting the liver.
Early results of a clinical trial of Mosquirix showed that three doses of the vaccine could cut the risk of infection in half for children between between five and 17 months old.
and somewhat ineffective vaccine may outweigh the benefits. Still, Africa is need in desperate for a malaria vaccine,
even if it's only partially effective. Malaria infection spread through the blood by mosquito bites kills upwards of 500
"This vaccine could mean children will have only two bouts of malaria a year instead of five,"Dr. Martin De Smet,
#Ebola vaccine is 100 percent effective in Guinea trial, WHO reports A vaccine is"highly effective"against Ebola, according to the World health organization.
Early results from a trial in Guinea show that the drug protected 100 percent of the people who received it against Ebola.
the vaccine could help end the outbreak in West Africa.""The initial results are exciting and very promising,
and the hunt for a vaccine continues. Now, it seems that scientists have a real contender on their hands.
4, 000 people with close ties to Ebola patients either received the vaccine immediately or three weeks after the identification of an Ebola patient in their social circle.
no cases of Ebola were reported, starting 10 days after the initial vaccination, which is needed the time period to develop immunity.
There were 16 cases of Ebola in the group that were given the vaccine three weeks later, however."
Starting July 26th, all of the study's participants were given the vaccine immediately, instead of putting half in a delayed group.
These results don't mean that the world now has an Ebola vaccine. The vaccine needs to undergo further safety and efficacy testing.
The vaccine is also being tested on frontline health workers, Bertrand Draguez, medical director at Doctors Without Borders, said in a statement."
"These people have worked tirelessly and put their lives at risk every day to take care of sick people,
"If the vaccine is effective, then we are already protecting them from the virus. i
#HPV Vaccine Is Effective Against Multiple Cancer-Causing Strains The human papillomavirus vaccine, Cervarix, not only has the potential to prevent cervical cancer,
"The study confirms that targeting young adolescent girls before sexual debut for prophylactic HPV vaccination has a substantial impact on the incidence of high grade cervical abnormalities,"researcher Dan Apter,
They found that the vaccine was extremely effective in young women who had never been infected with HPV.
The women were followed for up to four years post-vaccination. The vaccine was distinctly more effective among ages 15-17 than ages18-25,
underscoring the value of vaccinating young adolescents, said Apter. The study is the final report from the Papilloma Trial Against Cancer in Young Adults (PATRICIA), a multinational clinical trial encompassing 14 countries in Europe, the Asia-Pacific region
The overall trial constituted the basis for approval of the Cervarix vaccine in Europe and the United states. While the trial did not investigate the vaccine's efficacy in males, sexually transmitted HPV causes anogenital and head and neck cancers in both males and females.
HPV-related head and neck cancers now number around 8, 400 in the United states, annually."
"The more adolescents are vaccinated, the closer we will be to eradicating high risk HPV viruses, "Apter said."
"So I think boys should also be vaccinated.""Cervical cancer is the fourth most common cancer among women.
The findings are detailed in the journal Clinical and Vaccine Immunology y
#Mastercard seeks to move digital money fast NEW YORK Mastercard wants to speed up digital payments. The financial services giant has launched just Mastercard Send,
The health care worker measures the circumference of the child's upper arm.""The more malnourished they are,
"There are typically many more community health care workers. Finette couldn't train 500 new doctors, but he could arm 500 community health care workers with a tool that would make them the next best thing to a doctor."
"So that's where I came up with this idea of developing this medical intelligence platform anybody can be trained to use,
Finette found that many health care workers were ill-equipped to accurately determine those vital signs. Many of the workers, for example, don't have watches.
"Although this application is ordained to have impact in resource-poor areas of the world without access to quality health care
or health care at all, there's application in middle and upper income countries for a similar version of the platform,
"We're simply handing these to a preexisting workforce of health care volunteers who are already in place
"Yes, we want to provide appropriate health care to children who need it.""Contact Dan D'Ambrosio at 660-1841 or ddambrosio@freepressmedia. com. Follow him on Twitter at www. twitter. com/Dandambrosiovt.
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