Synopsis: Domenii: Banks & insurance: Banks & insurance colaterale: Pricing:


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and if that successful we want to go to 2400 satellitesbranson told CNBC on Thursday. he idea is to reach the billions of people who don have Internet access and to do so with good quality reception and good prices. elated:#


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At $46 per share, the deal price reflects a 51%premium to NPS Pharma share price of $30. 47 on December 16, 2014,

when speculation about a Shire acquisition of NPS surfacedut only a 9. 8%premium from NPSCLOSING price Friday of $41. 91.


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#Ensuring the Price Is Right for Cancer drugs The biopharma industry was rattled in 2012 when oncologists at Memorial Sloan-Kettering Cancer Center (MSK) refused to prescribe Zaltrap (ziv-aflibercept) for metastatic colorectal cancer due to its initial $11, 000-per-month cost.

while maintaining its official price. A year later, some 120 investigators and other experts in chronic myeloid leukemia (CML) publicly demanded lower cancer drug prices.

The group faulted high U s. prices in part on the failure of insurers and officials to negotiate drug prices with developers.

Now years of talk is finally translating into action on bringing down the price of cancer drugs.

Express Scripts, a pharmacy benefit manager that processed some 1. 3 billion U s. prescriptions last year,

recently disclosed it is in talks with several developers of cancer drugs to base the prices of several treatments on their effectiveness.

The payer won say which drugs or companies are the subject of discussions, first reported last month by The Wall street journal. Brian Henry, Express Scriptsvp,

Drug makers have resisted traditionally value-based pricing, arguing they need to recoup R&d costs. The about-face reflects the convulsive changes wrought by U s. healthcare reform

and Europe embrace of government-led value-based drug pricing. In the U k.,the National Institute for Health and Care Excellence (NICE) makes formulary determinations through a ost-effectivenessthreshold assessing estimated costs of treatments or services in relation to their expected health benefits.

Germany Institute for Quality and Efficiency in Health care (IQWIG) applies eference pricing setting reimbursements for new drugs at the same level as the best existing comparator unless the new drugs show superiority to that comparator;

U s. payers can be expected to approve higher prices for cancer drugs than the European agencies, in part given the greater size and affluence of the nation economy.

Dr. Bach published a commentary in Journal of the American Medical Association supporting indication-based pricing for cancer drugs.

the price of Erbitux (cetuximab) would dip from a typical treatment cost of $14, 292 to $10, 319 for locally advanced squamous cell carcinoma (SCC) of the head and neck.

But for its least effective indication of first-line treatment of recurrent or metastatic SCC of the head and neck, according to Dr. Bach, the price would plunge from $42, 875 to $471. ervoy and Keytruda, theye

Under his value model, Herceptin price for metastatic breast cancer would drop from a typical $54, 118 to $905.

As for pricing rare-disease drugs higher, Dr. Bach added: dispassionate economist would say that inefficient.

They can be expected to take different paths to pricing, hich means that there will not be a one-size-fits-all approach,

Numerous payers is one reason why prices set by U s. payers will likely be more palatable to drug developers than

then, will indication pricing have on cancer drug prices? ringing down the growth rate, yes. Actually reducing cancer drug prices across the board, very unlikely, Dr. Cohen concluded. n comparison to Europe, U s. prices will likely remain relatively high.

The growth rate will said shrink, he, as payer cut prices for less-effective treatmentsven after developers invest in IT systems, drug utilization programs,

The flipside of this is that the better treatments will still be commanding high prices, Dr. Cohen said.

Pricing decisions will hinge on data from providers: his is being presented as a way to manage money,

Abbvie agreed to an undisclosed lower price for Viekira Pak, which lists at $83, 319 per 12-week course.

Henry said the lower price is consistent with discounts given for the drug in Europe for Sovaldi,

That price brought upon Gilead criticism from Express Scripts and three members of Congress, all Democrats in the Republican-majority House of representatives.

000-a-pill pricing by noting that the cost of Sovaldi is lower than the cost of complications associated with hepatitis C treatment, such as liver damage or liver failure.

A Congress that can do little surely cannot lower cancer drug prices as effectively as payers could.

and have had discussions with several stakeholders about alternative pricing and payment models. Our discussions about pricing

and two other innovative pricing models: e understand that the cost of medicines can be challenging for some patients,

cautioned that some alternative pricing programs have helped developers skirt the prior-authorization rules of payers.

Representatives of two other top-selling cancer drug developers, Celgene and Amgen, at deadline had responded not to GEN queries on indication pricing


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Prices range from US$1, 200 to $3, 500, depending on engine size, which can vary from a 100cc scooter to a Super Panamax ship p


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or when it best fits their utility pricing program. But seamless integration between devices and utility programs is coming.

utilities will have to develop novel pricing programs that can take advantage of the devices. Chargepoint is one of the companies that also announced it is integrating its residential EV charger with the Nest thermostat h


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#SMA Plans Layoffs of 1600 Sending Its Stock Price to All-time Low SMA Solar, Germany's biggest solar company, is set to cut about 1, 600 jobs,

putting pressure on equipment prices and profit margins. Chicago tribune: Former Opponent Touts Nuclear power at Chicago Event Not too long ago, Carol Browner would have sided with the activists clad in white hazmat suits protesting nuclear power outside the City Club's lunch Tuesday in downtown Chicago.


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Anthony Price, director of the Electricity Storage Network, explains: The UK electricity and natural gas regulator Ofgem has calculated that it will cost £50 billion $76 billion to rewire Britain.

Price organization is lobbying for a minimum 2, 000 megawatts of new network-connected electricity storage by the year 2020.


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he said. e will enter at a very competitive price, but the volumes will be lower.


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or whether the price will be cost-prohibitive I don't know. But I think people are going to continue to push the envelope to see how the chips could be leveraged.


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thus permits mass production and hence lower prices that will ensure more widespread commercial use of silicon photonics.


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So the overall cost spread over time would be roughly equal to the price of the fossil fuel infrastructure, maintenance and production."

"When you account for the health and climate costs-as well as the rising price of fossil fuels-wind,


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The price, thanks to the simplicity of the design, will most likely depend on the number of sensors,


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This major finding could potentially save millions of lives and at only a fraction of the price of modern cancer treatments.


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And this collapse in property prices is for properties that still have running water. What happens when the water supply to a $30 million estate is cut off?


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Wicab told Popular Science that it will cost $10, 000 per unit, the same as its price when first reported back in 2009.


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if the price of producing the substance falls far enough to make it economically viable. Right now, the research group at Bristol says that"self-healing nail polish will have to wait


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In Kenya Mathare slum, for example, residents must purchase frequently dirty water from vendors who charge exorbitant prices for access.


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price appropriate solution that in the near future should start to see commercial usage.""O'brien has described previously self-powering wearables as"the Holy grail"for the tech industry


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"It means that consumers can look forward to more competitive pricing in the solar energy sector, and according to Dr Jones, the discovery is shot a-in-the-arm for the whole organic materials sector."


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and trade and rising food prices are triggering the food crisis. Experts participating in the Global Rice Market

and Trade Summit organized by the International Rice Research Institute (IRRI) in Bangkok Thailand in October 2014 remarked that there was a noticeable rise in the local rice prices in the affected countries

and its price and accessibility directly influence social stability. Annual per capita consumption of rice (about 100 kg) is amongst the highest in Sub-saharan africa.


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Protection at an affordable price In 2004, MVP partnered with SIIL to develop an affordable, tailor-made vaccine for use against meningitis A in Sub-saharan africa.

"Developing the Menafrivac vaccine fit exactly Serum's ingrained philosophy of bringing down prices of vaccines

and deployed across multiple countries at a price that was sustainable.""""The benefits of childhood immunization last a lifetime and the Menafrivac vaccine is one of the greatest success stories that shows


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and probably increase prices where quality can be guaranteed d


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#Noncoding RNA CCDC26 regulates KIT expression An long noncoding RNA (lncrna), which might give an impact on tyrosine kinase-targeted leukemia therapy,


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Power prices may also rise as hydroelectric plants have difficulty generating with low water flowsnd to the extent that very complicated power distribution affects a larger region,


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#China stock market plunges Share prices in China plunged Friday in one of the sharpest sell offs in years,

Share prices in Hong kong, which is regulated separately, also weakened, dropping 1. 8 percent. Analysts had been warning for months about the risks of a stock market bubble in China,

where giddy investors have driven up stock prices by purchasing shares on margin, with money borrowed from brokers.

share prices of many companies on the exchanges have skyrocketed during the past year. Many traded at record valuations, often 80,90 or 100 times their projected earnings.

which is believed to be one of the key reasons for a stock market rally that has sent share prices to seven-year highs.

Although stock prices are still up significantly from a year ago, with the Shanghai composite reaching 5, 166.35, up as much as 160 percent in the past two years


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The price will rise to USD 2, 995 next month. Website: www. juneoven. com Contact:


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at the price point we are aiming for. To be honest, without something like eye tracking,


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However one drawback is its high price; even its processing can be tough. These are the reasons why carbon fiber-reinforced plastics (CFRPS) have still not yet found their path into wide-scale serial production so far to date.


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Others working on this project include Jared Price, graduate student Penn State; Xing Sheng, postdoctoral fellow; John A Rogers, professor of materials science and engineering, University of Illinois, Urbana Champaign;


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Researchers hope that as the new HUS Hycopter hits the market later this year (no word on the pricing yet), hydrogen fuel cell technology,


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Professor Henry and his colleagues are eager to produce new premium wheat varieties. he good news is that premium wheats attract better prices so this discovery potentially means more dollars for Australian farmers.


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#New Self-Destructing Devices to Lead the Way towards Sustainable Electronics Thanks to falling prices, increasing demand and short lifespans of most consumer appliances,


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which has announced its plans to release a commercial version of the aircraft in 2017 with a sticker price of 85.000 US dollars.


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increases efficiency and lowers the price of those goods and services. It is not just Uber that is facing resistance over the sharing phenomenon.


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A report from Deutsche Bank this year said solar energy storage would be cheap enough to be deployed on a large scale within five years as a result of a yearly cost reduction of 20%to 30%in the price of lithium-ion


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the average price of in vitro fertilization hovers around $12, 400. If clinics could tell patients


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Mr Mcloughlin also said the cost of the arm needs to be about a tenth of its current price to be viable in the marketplace.


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It's yet to be seen how much it could add to the price of a new car,


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it easy to see the price falling further. One scenario being bandied about is using these CICADAS to monitor extreme weather situations, such as tornadoes.

that price might drop to as low as $250. In terms of simplicity, theye basically a iece of cardboard with a circuit board.


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#Hardware prices could come down after WTO tariff repeal on chips, switches and touchscreens Consumers may see prices for certain tech products fall thanks to a new trade deal between 54 World trade organisation (WTO) members.

According to the WTO, the 54 members have agreed to cut tariffs on a list of 201 IT products with that account for $1. 3 trillion in trade each year.

It will support lower prices-including in many other sectors that use IT products as inputs-it will create jobs


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