Using brain scans from the ENIGMA Consortium and genetic information from The Mouse Brain Library he was able to identify a novel gene,
MGST3 that regulates the size of the hippocampus in both mouse and human, which is linked to a group of neurodegenerative diseases.
and the corresponding genes and then matching those with genes in mice from the BXD system held in the Mouse Brain Library database we could identify this specific gene that influences neurological diseases."
The Mouse Brain Library, established by Professor Robert Williams based at the University of Tennessee Health Science Center,
But patterns of electric signals are sent by a computer into nerves in his arm and to his brain,
"They change things on the computer to change the sensation.""One time,"he said, "it felt like water running across the back of my hand."
Intelligent programming uses computer memorythe program uses the smartphone's built-in camera to register its environment.
Many movement-recognition programs need plenty of processor and memory power explains Hilliges adding that their new algorithm uses a far smaller portion of computer memory
and is thus ideal for smartphones. He believes the application is the first of its kind that can run on a smartphone.
Gesture control will not replace touchscreen control but supplement it. People got used to operating computer games with their movements.
Touchscreens Hilliges reminds us also required a very long adjustment period before making a big impact in consumers'lives.
He is therefore certain that this application --or at least parts of it--will find its way onto the market.
that displays a functionally critical region of the virus that is universally conserved in all known species of Ebola.
Importantly, the researchers were able to demonstrate this peptide target is suitable for use in high-throughput drug screens.
These kinds of screens allow rapid identification of potential new drugs from billions of possible candidates.
and colleagues have shown that a lentivirus encoding let-7 injected into mouse neurons promotes the autophagic turnover of toxic misfolded proteins associated with neurodegenerative disease. e also demonstrate that treatment with anti-let-7 can block autophagy
"And even if the conversation is encrypted--in principle--it is still possible to decrypt it provided you have sufficient computer power,
In the USA alone, the phenomenon costs businesses around USD 100 billion every year according to a 2014 report on the subject by security firm Mcafee.
which facilitates the reconstruction of the brain's anatomic data as a 3d model on the computer.
and materials science professor Noah Malmstadt and biomedical engineering graduate student Bryant Thompson designed computer models for eight modular fluidic and instrumentation components (MFICS pronounced em-fix) that would each perform a simple operation.
The team attributes much of the success in the fabrication stage to recent advancements in high-resolution 3-D printing.
and imaging software to visualize it at a resolution of less than a billionth of a metre.
#Silicon oxide for better computer memory: Use of porous silicon oxide reduces forming voltage, improves manufacturability Rice university's breakthrough silicon oxide technology for high-density next-generation computer memory is one step closer to mass production thanks to a refinement that will allow manufacturers to fabricate devices at room temperature with conventional
production methods. First discovered five years ago, Rice's silicon oxide memories are a type of two-terminal,"resistive random-access memory"(RRAM) technology.
Beyond the use for a harder spinel in armor windows there could be other potential Dod and civilian applications in better/stronger office windows smartphones and tablets screens military/civilian vehicles
#Advantages, potential of computer-guided spinal surgery In a series of research studies Cedars-Sinai spinal surgeons show that a new method of computer-guided spine surgery is beneficial for spinal reconstruction
Computer-guided surgical navigation technology delivers on quality and safety said J. Patrick Johnson MD a neurosurgery spine specialist and director of Spine Education and the Neurosurgery Spine Fellowship program in the Department of Neurosurgery.
The images are transferred to a computer which displays them on overhead monitors that allow precise tracking of surgical instruments as surgeons insert screws for reconstruction
and perform other complex procedures on the spine. Surgeons said the technique is superior to existing methods because of its precision and speed.
because hardware was initially out of place. The Cedars-Sinai surgeons say they have cut these to nearly zero by using computer-guided methods.
The surgeons said the technology has others applications for treating spinal disorders serving as a tool to remove tumors decompress the spinal column
This approach represents a major leap forward for instrumented spine surgery said Terrence T. Kim MD an orthopedic spine surgeon in the Cedars-Sinai Spine Center and expert in the computer-guided navigation field.
and computer-aided system used during minimally invasive surgery increased the accuracy of screw placement into vertebral pedicle bones.
The final two articles offer an overview of computer-guided surgery of the spine including its use in revision
and the potential future use of robotic spine surgery with computer navigation. The special issue of the journal can be accessed at:
All have shipped their inventions to Delhi where they will be on display March 22 for scientists engineers and dignitaries.
North american zooplankton like many Daphnia and Bosmina species which are favorites on Bythotrephes'menu have similar hardware
We have an array of emitters that can be thought of as a dot matrix-printer printer, where you would be able to individually control each emitter to print deposits of nanofibers.
Melanie Gonick/MIT (with computer simulations from Alexei Bylinkskii) Friction and force fieldsthe team simulated friction at the nanoscale by first engineering two surfaces to be placed in contact:
#Engineers Develop a Computer That Operates on Water Researchers at Stanford university have developed a synchronous computer that operates using the unique physics of moving water droplets.
Their goal is to design a new class of computers that can precisely control and manipulate physical matter.
Computers and water typically don mix, but in Manu Prakash lab, the two are one and the same.
and his students have built a synchronous computer that operates using the unique physics of moving water droplets.
The computer is nearly a decade in the making incubated from an idea that struck Prakash
Because of its universal nature, the droplet computer can theoretically perform any operation that a conventional electronic computer can crunch,
or to operate word processors on this, Prakash said. ur goal is to build a completely new class of computers that can precisely control
and manipulate physical matter. Imagine if when you run a set of computations that not only information is processed
Computer clocks are responsible for nearly every modern convenience. Smartphones, DVRS, airplanes, the Internet without a clock, none of these could operate without frequent and serious complications.
Nearly every computer program requires several simultaneous operations each conducted in a perfect step-by-step manner. A clock makes sure that these operations start
Prakash explained. he reason computers work so precisely is that every operation happens synchronously; it what made digital logic so powerful in the first place,
A magnetic clock Developing a clock for a fluid-based computer required some creative thinking.
Prakash said the most immediate application might involve turning the computer into a high-throughput chemistry and biology laboratory.
and the droplet computer offers unprecedented control over these interactions. From the perspective of basic science, part of why the work is so exciting
Right now, anyone can put these circuits together to form a complex droplet processor with no external control something that was a very difficult challenge previously
With its current power output, the floating evaporation engine could supply small floating lights or sensors at the ocean floor that monitor the environment,
and even livestock would have embedded their own sensors that report information directly to networked servers,
These regenerators are effectively supercomputers and must be applied to each channel in the transmission. The electronic regeneration in modern lightwave transmission that carries between 80 to 200 channels also dictates the cost and,
as well as in computer and television screens. sing quantum dots for spectrometers is such a straightforward application compared to everything else that wee tried to do,
such as labeling cells or new types of TV screens, exploit quantum dotsfluorescence a property that is much more difficult to control,
which vary greatly in their ability to damage skin. he central component of such spectrometers the quantum dot filter array is fabricated with solution-based processing and printing,
which are needed for brief transmissions of data from wearable devices such as heart-rate monitors, computers, or smartphones, the researchers say.
because of 3-D printing, is relatively cheap and fast. The robot body transitions from soft to hard, reducing the stress where the rigid electronic components join the body
senior author Robert J. Wood, Charles river Professor of Engineering and Applied sciences at the Harvard John A. Paulson School of engineering and Applied sciences (SEAS) and core faculty member at the Wyss Institute for Biologically Inspired
a soft plungerlike body with three pneumatic legs and the rigid core module, containing power
and protected by a semisoft shield created with a 3-D printer. The design builds from previous work of co-author and chemist George Whitesides, the Woodford L. and Ann A. Flowers University Professor at Harvard.
This new design demonstrates the potential of 3-D printing in soft robotics. Traditional methods of fabrication custom molds and multistep assembly are costly and slow.
The ever-increasing variety of materials compatible with 3-D printers is allowing engineers to prototype new designs faster.
and 3-D printing is adding to the repertoire of things we can do in a really practical way,
These have been named Pc (4450)+ and Pc (4380), +the former being clearly visible as a peak in the data,
Nanoparticles made from these polymers have a hydrophobic core and a hydrophilic shell. Due to molecular-scale forces
BPA, another endocrine-disrupting synthetic compound widely used in plastic bottles and other resinous consumer goods, from thermal printing paper samples;
The researchers confirmed that a gene known as NF1 is a ajor playerin the development of skin cancer. he key finding is that roughly 45%of melanomas that do not harbor the known BRAF or NRAS mutations display loss of NF1 function,
This panel of genes can now be used in precision medicine to diagnose malignant lesions and can be applied to personalized cancer treatment.
and pressures at their cores necessary to trigger the thermonuclear reactions that power ormalstars. Theorists suggested in the 1960s that such objects should exist
Sesame street and other children programming is delivered on mobile devices to young children. A third-party study found children in the program showed significant gains in comprehension, language and word knowledge.
Business classes are delivered wirelessly to tablets, which also let women in the program communicate with mentors.
which allows people to store digital wallets securely on their mobile devices. Credit card and other payment information can be stored in the digital wallet
#IBM Smarter Cities Challenge is back: Could your city use some pro bono problem solvers?
But Council Lead Partner IBM has been doing just that with its Smarter Cities Challenge for the past four years.
IBM is continuing the grant program this year and is now accepting applications from local governments.
That's the idea behind IBM's Smarter Cities Challenge competitive grant program that has in the last four years helped 116 municipalities around the world solve critical local challenges.
How it works After intense preparation, six-person IBM pro bono consulting teams spend three weeks in the winning region analyzing all available data about a critical issue of the municipality's choosing for example
At the conclusion, IBM presents comprehensive recommendations for improving the delivery of services to citizens.
Past winners have seen results IBM notes that many of its past grant recipients have implemented their Smarter Cities Challenge recommendations
A program that works"We're extending IBM's Smarter Cities Challenge for one simple reason:
It works,"said Jennifer Crozier, IBM vice president of Global Citizenship Initiatives.""City leaders from around the world have told us how IBM's advice has helped them re-imagine how they can use data
and analytics to help them solve complex problems. We're told that IBM Smarter Cities Challenge is that rare program that brings people together
and gets long-term results --and we're proud of that. We invite mayors and regional leaders to apply with their toughest problems
Using data analysis technology from Council Lead Partner Microsoft, they are able to position officers where they will make the biggest difference.
How it works Microsoft Domain Awareness System gets most of the attention for its work in preventing crimes.
While the analytics were built by Microsoft, New york city police officers guided the development. Police officers described their biggest pain points
Doesn break the budget Microsoft is quick to point out that these benefits are available to cities of any size at a very modest investment.
The panels in the $3. 7 million project are linked to smart meters that increase their output
Solar Roadways developed its first road panel in 2009 and with the help of additional grants, finished up an experimental solar-paneled parking lot last year.
It plans to use money from its successful crowdfunding to take the version of the panels it used for that project into production i
The city has partnered with Council Lead Partners Cisco and Microsoft in addition to Fiberco, the Technology Innovation Agency and Nunnovation Africa Foundation on the program.
Council Lead Partners IBM Microsoft, andcisco and Associate Partner Siemens have been working with Chinese companies on national information security as well as technologies
and solutions to support the growth of smart cities there. Council Lead Partner Itron, meanwhile, completed installation of smart water, heat and gas meters and communication modules as well as its fixed network for Sino-Singapore Tianjin Eco city in Tianjin, China.
"I don't want to live in a place where computers run my life. You're installing a whole bunch of computers
which will do a whole variety of things but you're forgetting that cities are for people.
and a processor to run the show. The Trakür is no exception. Developed in the suburbs of Buenos aires by INTA's rural engineering division, the yellow and white robot resembles a child's Tonka truck (the chassis) with a lighthouse (the sprayer) strapped to the top.
and the amount of remaining chemical to a computer outside the greenhouse, where an operator directs the Trakür virtually.
an add-on for Microsoft Outlook that manages messages from a collaborative perspective. Decisiv Email offers more than a carbon-copy of what's going on
the software either files that message in a folder that it believes relevant on its own
that you have to use Outlook for the categorization to happen. Recommind is working on tablet and smartphone integration.
What about privacy, you ask? A tool like Decisiv Email will definitely make you think twice about what you write in an email or about
and now there's a website to find nearby 3d printers for quick turnaround on printing jobs. makexyz. com is a simple website that allows anyone with a 3d printer to rent out their services to anyone with printing needs.
with the cheapest showing up first with all the details of the printer. Need to print with full color sandstone?
The closest printer to me, for example, is a Prusa Mendel I2 that uses#ABS Plastic in numerous colors.
I pay right there (no money is exchanged between printer owner and designer). Then, once the printing is complete
I can pick it up or have shipped it to me. Zak Stone reports for Fast Company that people with 3d printers have been eager to sign up:
Already, more than 500 printers around the United states have signed up--with everything from homemade printers, to Makerbots, to $30, 000 professional machines.
(or other printing service chains) become the Kinko's of 3d printing? With widespread stores already in place, a forward-thinking chain could make 3d printers available and more accessible.
but 3d printers in big cities and college towns, at least to start, could really help evolve their printing chain's brand.
software developers, and Internet users to create next-generation broadband applications. The partnership includes 25 cities around the country,
and recycling electronic products such as televisions, refrigerators and computers. A tax will be added to the price tags of electronic products to help pay for e waste disposal.
In California, there is a $10 fee added to the price of electronic products with viewable screens,
The Personal Genome Machine vs Miseq videos played off the Mac vs PC ads. People are crying out for independent analysis,
For the purposes of the survey, Deloitte defined influence to include activities such as product research conducted by shoppers with their mobile device,
Microsoft is also hoping to benefit from the phenomenon. Its Microsoft Tag mobile scanning technology supports both 2d barcode formats (including QR Codes and the Tag format) as well as Near Field Communications.
This month, Procter & gamble are running a month-long test in the Chicago and New york areas of pop-up stores,
One example is Goodzer, a local shopping search engine that covers inventory from more than 500,000 stores in the United states s
The fact that a firm that produces mobile devices is now more valuable than an oil company is the most powerful repudiation of the sprawling, exurban, oil-dependent old economy
mobile devices are suited uniquely to the urban environment. They are such powerful connectors of people that they are literally replacing their need and desire for cars.
and use other technology instead, such as smartphones and tablet computers. It's not merely that the two trade off economically;
so to their mobile devices and always-on connectivity that they would sooner give up driving. Pendleton continues:
Gen Y housing preferences are the subject of at least two panels at this week s convention.
who are making decisions every day to buy an ipad instead of a new car, or to move closer to work
and to be close enough to the job opportunities represented by America's urban cores,
How might this kind of technology relate to ipad and iphone maker Apple? The patent application is not a huge indicator,
Producing APIS will not be the exclusive domain of software companies or large enterprises. The key thing about the API economy is you can't just consume APIS.
#Why open source may win the electronic health record market Electronic Health Records (EHRS) are the trend of the day.
first developed in the 1980s and released in this decade as open source, was falling. The Bush administration starved Vista of development funds, preferring a system of contracts and contractors who used HIMSS-approved gear.
At the peak of the fight the VA even lost control of its own lab software system to Cerner
and its open source approach. Suddenly, it seems, Vista has the advantage. This was proven for me today, through an interview with Paul Hensler (above), CEO of the Kern Medical center in Bakersfield, California.
Plus millions of dollars for the software. Enter Medsphere a commercial supporter of Vista software.
Their Openvista is open source. Kern could download it, call it free, and then sign a professional services contract with Medsphere for support.
Suddenly, a two-year contracting process could be squeezed into six months. And with the first deadlines for getting stimulus money coming in 2011,
thanks to open source. It was an incredibly short decision time frame for a county. A lot of our doctors did their training at the VA. We knew we could download it
and other issues the VA software doesn't support. I think we came across Medsphere in late April.
This is the way open source is supposed to work. The software is free, but you need help,
and the support contract also gives you control of the final result. You also get help from all the other users of the same software.
But this is an advantage I had not been aware of. Since you don't buy open source, you can sign a professional services contract with an open source consultant
and clear through several bureaucratic processes at a stroke. If the Obama Administration has done nothing else
it seems, it has transformed the market for EHR software. Open source, which had been left for dead a year ago,
is suddenly in the lead d
#Why people need robot journalism in the Google era Kristian Hammond quit artificial intelligence 10 years ago,
but that is exactly when he created an intelligent machine. Hammond is a professor at the Intelligent information Laboratory at Northwestern University,
who has built a computer that can create movie reviews by curating text online found on blogs and on Twitter.
We are looking at computer generated content. We got to a point where we were generating from existing text online,
Whatever document you needed it was most likely that Jason had it in a folder on his hard drive.
Relative to 10 years ago, Americans have changed completely their outlook about learning a language. We ve seen a shift about the age that parents want their children to start learning.
And in the future, wireless charging technology won't be limited just to powering more mobile devices. It could have applications for large-scale appliances
Toyota announced in December that the 2013 Toyota Avalon Limited will be the first car to offer wireless charging with a Qi-powered console included under the dashboard.
But an upcoming revision in the second quarter of 2013 will see Qi extended to support wireless charging up to a level of 15 watts, enough power to charge consumer tablets.
The ability to charge laptop computers wirelessly isn't yet supported, but plans are on the near-term roadmap.
A marble countertop, for example, could be rigged to charge a wireless coffeemaker and a blender along with a variety of phones, tablets and computers as needed.
These sensors connect to backend servers that process the data collected, and the information is displayed as requested by the customer.
personal digital assistant or PC. Information that is collected includes temperature, humidity, and soil nutrients. The solution was developed by Bulut Ersavas,
a former electronics engineer with IBM and Sun who got the idea for a water-monitoring system
But the equally colossal pieces of Styrofoam that protected the computer in shipping more than two decades ago are gone long,
which could even be your computer or TV. Steelcase one of the largest office furniture makers in the world--they ve been really happy with Ecocradle,
We re launching Ecocradle in the computer market. There s one big client that will be using it (we will be releasing the name in a couple weeks.
#Google unveils deforestation monitor to combat climate change The philanthropic arm of Google, Google. org, introduced on Thursday a deforestation monitor that could be a useful tool to combat climate change.
"the company can crunch the massive amounts of data stored on Google's servers to instantly produce,
indicating that the core business model is financially sustainable. This is a significant rise. Why? Some say that it new Wi-fi enabled busses that is luring people to leave cars behind
Since tablet adoption is about to experience exponential accelerated growth, with tablets eclipsing lap top sales by 2015.
And tablets function with Wi-fi. From Salmon post: So far, no one really cracked the problem of the mobile web wee still in a world where connecting to the internet
when on the move is far too difficult, and needs to be configured (and often paid for) on a device-by-device basis
Collective-Evolution notes that the solar panels embedded in the concrete bike path are not as efficient as panels installed on homes
I was drawn soon to continuous glucose monitors (CGMS. These report blood glucose levels every 5 minutes, thanks to a small radio transmitter attached to a fine sensor wire that runs under the skin (the wire is replaced weekly, the transmitter every six months.
but I knew that the Dexcom G4 receiver could furnish glucose data via its USB port.
Dexcom own Windows software was pulling data in this way, and fortunately, Dexcom supplied an API (application programming interface) library as part of its software installation.
It took about 3 hours to code A c#program that polled the receiver and uploaded the data to a Google spreadsheet.
We sent Evan to day care with a small laptop equipped with the receiver. While he was in his classroom,
we could see his blood glucose via either a simple website or an ios app I threw together.
It was life changing, as it allowed Evan some freedom from the typical type 1 diabetes regimen at day care.
or long walks, putting him out of range of the laptop receiver, we were blind again.
Thus began my work on a truly ambulatory solution, based on a smartphone rather than a laptop.
My family primarily uses ios devices, but power limitations and closed frameworks made hooking up the receiver to an iphone far more difficult than to an Android phone.
I got a Motorola Droid Razr M phone and once I had the basic USB enumeration downo my phone could eethe receiver
when it was plugged in started decoding the G4 communication protocol. Using the same C# program as before,
and captured the USB traffic as it flowed between my computer and the receiver. With this data,
I wrote an Android app to extract glucose data and upload it to our Google spreadsheet via the cellular network.
In my excitement, I tweeted my discovery. What happened next was incredible. Another iabetes dad, Lane Desborough, contacted me.
and continued to refine the Android app over the summer, in preparation for Evan return to school.
While Dexcom has released subsequently Share, a proprietary remote-monitoring system, it works only with ios devices.
I had written software that lets me see Evan glucose level at a glance. Lane and I (along with Ross Naylor) continued to collaborate,
and in early 2014, we made the C# uploader, Android app, Pebble watch, and Nightscout code open source. Subsequently,
better software engineers than I have improved the code and made it easier to use; a Facebook group for Nightscout, set up by Jason Adams,
now has nearly 12,000 members, and our code made the semifinal round for the 2014 Hackaday Prize.
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