#French start-up develops in-vitro human sperm A French start-up working with a government lab said it has developed in-vitro human sperm, claiming a breakthrough in infertility treatment. Though researchers with Kallistem had announced the discovery previously, its working was described for the first time on Thursday. They have developed so far sperm from immature cells known as spermatogonial cells, which are present in all males, and develop into sperm cells once puberty starts. The technology now has to be tested clinically. Philippe Durand, the chief researcher, said genesis of the research was indications that male fertility was declining which could be attributed to environmental factors. Since"at the heart of the problem is the interior of the testicle, "he said. The research team developed a bioreactor using a viscous fluid made partly of substances found in the walls of mushrooms or in crustacean shells to reproduce the conditions within the body. The main challenge was reproducing in the lab a complex physiological development process that usually lasts 72 days in a human, from immature cell to sperm. In each case,"they took the entire path they would have taken in the testicle in our in-vitro system"said Durand. Young men with cancer could be helped by the process s
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