#ab-In-A-Needledetects Liver Toxicity In 30 Minutes The researchers are currently working on a prototype that miniaturizes a test lab into the size of a needle. This ab-in-a-needledevice will be effective, for example, in quickly detecting liver toxicity, a common side effect of chemotherapy. Current tests entail multiple steps and results could take several days. Instead, the compact kit can take patient samples, prepare them for testing, evaluate toxicity and display the results in one simple process. Dr. Wang Zhiping, Director of research Programs at Agency for Science, Technology and Research's (A*STAR) Singapore Institute of Manufacturing Technology (SIMTECH said, ur goal is to integrate sample acquisition and preparation into one device, a significant challenge that has slowed the development of point-of-care testing. The ab-in-a-needletest kit has two key components: a microfluidic chip that extracts and cleans the required test sample from the blood, while the second chip runs the various tests on the purified blood sample. It is the brainchild of a joint research team from Singapore Nanyang Technological University (NTU Singapore), SIMTECH and the Houston Methodist Hospital Research Institute. NTU Professor Joseph Chang, who is involved in the design and construction of the prototype, said, hat our prototype shows is that samples can be prepared and analysed through it, eliminating the need for wet laboratory work and manpower. ur new method significantly reduces time, manpower and costs and yet has the same accurate results as the gold standards of current liver toxicity tests, added Chang, who is also the Director of VIRTUS Center of Excellence in Integrated circuit Design at NTU School of Electrical and Electronic engineering n
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