The complex sugar structure in glycoprotein can be subtly different between samples from healthy and diseased patients.
which has specific sugars in a specific location in the molecule. Professor Mendes added""Biomarkers such as glycoproteins are essential in diagnostics as they do not rely on symptoms perceived by the patient,
the sugar part of the prostate cancer glycoprotein is reacted with a custom-designed molecule that contains a boron group at one end (the boron linkage forms a reversible bond to the sugar).
The glycoprotein is then bound to the surface via its sugar groups, before the rest of the surface is blocked with a third molecule.
Within that cast, there was a special area with boron-containing molecules that can recognise a specific set of sugars.
so there's a clear need for more accurate diagnosis. By focussing on the sugar, we appear to have hit the'sweet spot'for doing just that.
push large quantities of salt water through and the salt will be rejected on the basis of size
We may include less of the antimicrobial ingredient without losing effectiveness while at the same time using an inexpensive technique that has a lower environmental burden.
and approved by the Food and Drug Administration as a food additive, and polylactic acid, a biodegradable plastic used in compostable cups and glassware.
In that case, both the plastic and the oil-based sauce are hydrophobic and interact together.
to replace the widespread use of organic solvents for everything from decaffeinating coffee to making paint thinners.
Overwatering puts pressure on an already scarce and expensive resource increases pollution from nutrient-rich runoff affects the quality of the fruit
#Scientists Discover Nutrient Sensor That Senses Amino acid Arginine Through a variety of mechanistic interactions mtorc1 interprets cues in the cellular environment including the availability of nutrients
and dial back metabolism when food is scarce. Owing to years of intense scrutiny in the lab of Whitehead Institute Member David Sabatini the key players of this pathway
How exactly does mtorc1 actually detect the presence of nutrients? Now it seems scientists in Sabatini's lab have at least a partial answer describing for the first time a protein that appears to sense the amino acid arginine.
Taken together such compelling evidence points to SLC38A9 as an amino acid sensor tipping off the Rags to the availability of nutrients.
Although the discovery of the first nutrient sensor in this pathway represents an important advance the researchers know much work lies ahead.
It may also prove useful in discovering concealed goods in the retail industry or for non-destructive monitoring, for example quality control in drugs or food.
A couple there plied him with tea and snacks, then quietly asked if he could spare any of his own food for them.
Their daughter had developed a respiratory problem because of the haze. The surprise medical bill coupled with the fire destroying their oil palm crops,
Palm oil is an ingredient in a range of consumer products from lipstick to ice cream. Yet it has helped also to give its source country the dubious distinction of being the world third-largest greenhouse gas emitter after China and the US as well as a leading source of hazardous smoke haze.
What more, peat fires are notoriously hard to predict and extinguish. They start and spread easily,
#'Home-brewed morphine'made possible Scientists have figured out how to brew morphine using the same kit used to make beer at home.
They have modified genetically yeast to perform the complicated chemistry needed to convert sugar to morphine.
If you brew beer at home, then you are relying on microscopic yeast that turns sugars into alcohol.
But by borrowing DNA from plants, scientists have been genetically engineering yeasts that can perform each of the steps needed to convert sugar into morphine.
One stage of the process-the production of an intermediary chemical called reticuline-had been a stumbling block.
which is a cheap sugar source, and have the yeast do all the chemical steps required downstream to make your target therapeutic drug."
and basic skills in fermentation would be able to grow morphine producing yeast using a a home-brew kit for beer-making,
Among the ideas for household robots are machines for cleaning, cooking, or loading and unloading dishwashers.
Biofuel sweetspot"We've identified a new route of chemistry with its source from sugars in sugarcane plus some of the so-called waste material called bagasse"
Food v fuel In recent years, political support for biofuels has waned as concern grew that global demand for biofuels would result in a switch away from food production to biofuel production, exacerbating food security worries.
Prof Bell acknowledged that certain crops as feedstock for the sugar-derived process would be problematic:"
"If, for example, we were to use sugar beet instead of sugarcane then there would be a potential conflict over fuel versus food."
-in order to make it available for growing sugar plantations, and you get rid of that vegetation by burning it then you are putting a big pulse of CO2 into the atmosphere."
#Hackers steal data using pitta bread Secret encryption keys can be stolen using a cheap gadget so small it could be concealed inside some pitta bread.
The new machine mimics the pumping mechanism of life-sustaining proteins that move small molecules around living cells to metabolize and store energy from food.
For its food, the artificial pump draws power from chemical reactions, driving molecules step-by-step from a low energy state to a high-energy state--far away from equilibrium.
and make the main cell types of neurological systems-the central nervous system and the peripheral nervous system-in a dish that is specialised for each patient.'
or be used to look at contamination, for example in food or milk. The team has been able to convert the mobile phone into a sensitive E-coli or giardia detector,
If the person needed to be tested every few hours, before a meal, after a meal,
From sugars to viral invaders to nerve impulses all cellular traffic passes through the cell membrane, and likely interacts with the proteins embedded there, such as neurotransmitter and hormone receptors.
to use CRYO EM to visualize the structure of the body receptors that sense the spiciness of chili peppers and, in work reported last month, wasabi.
when compared to more influential variables like diet and exercise. The new data are consistent with previous research on individual diseases.
a natural substance that is an ingredient of many cosmetics. The second was 2-nitroimidazole or NI,
they decided to incorporate these balls of sugar-sensing, insulin-releasing material into an array of tiny needles.
Gu created these icroneedlesusing the same hyaluronic acid that was a chief ingredient of the nanoparticles,
or the diet but the fact that you have to do them all several times a day every day for the rest of your life,
After that, the Gates Foundation took interest. t wasn just a pie-in-the-sky idea anymore wee really treating patients
including sugars, which allow the bacteria to be controlled by the food that is eaten by the host,
Voigt adds. Bacterial emory To sense and report on pathologies in the gut, including signs of bleeding or inflammation,
The researchers used it to modulate the ability of B. thetaiotaomicron to consume a specific nutrient
When the mice were fed food containing the right ingredients they showed that the bacteria could remember what the mice ate.
as the bacteria were directing the robot toward more food, the robot paused before quickly making its final approach a classic predatory behavior of higher order animals that stalk prey.
The 56-year-old dietitian from Syracuse, New york, had to give up bicycling because the disorder affected her balance.
In lab dishes, the group assembled Cas9 ribonucleoproteins, or RNPS, which combine the Cas9 protein with single-GUIDE RNA.
and bile reflux when the stomach juices come back up the gullet. Between one and five people in every 100 with Barrett's oesophagus go on to develop oesophageal cancer in their life-time,
It can also be used to identify potential allergens in food, among other applications. A team of researchers from the California Nanosystems Institute at UCLA has developed a new mobile phone-based device that can read ELISA plates in the field with the same level of accuracy as the large machines normally found in clinical laboratories.
#Approval for AIDS Vaccine at Canadian University The Food and Drug Administration has given Canadian researchers approval to test a vaccine for HIV/AIDS on humans.
Ka coffee and macadamia nut growers have been impacted as well. e had a USDA (Farm Service agency) meeting (Tuesday) morning down here with some of the farmers.
and coffee, said Randy Stevens, with Ka Farms Management and manager of Ka Coffee mill. Stevens said early estimates for his company are about 1,
000 coffee trees damaged. e have 100 acres of coffee. It probably less than 10 percent of our overall field,
and mustard) and later with sugarcane the team introduced genes that boost natural oil production in the plant.
Many of BIO Food & Agriculture Section members are doing their part to help improve pollinator health
#The New Food Economy: How Innovation is Transforming Agriculture Data analysis and computational technologies are giving farmers the ability to monitor their land better,
Nanette Byrnes, writer for the MIT Technology Review, calls this the ew food economy. y combining this information with data generated by soil sensors and weather reports,
Food-tech startup investment rose to $1 billion in the past year according to CB insights, and is popular among Google Ventures, Silicon valley,
and creative investors to ensure economic stability and food for all. Farmers now have the ability to make choices that are affordable, effective,
That's where we get out secret sauce from.""Behaviosec's tech plugs directly into banks apps and websites,
#Scientists made a major breakthrough in 3d-printed electronics that will keep you from ever drinking spoiled milk again Researchers have used 3d printing to develop a sensor that can be placed inside a carton of milk to detect
if the milk is fit for drinking and to alert if the milk has gone off."
The US Food and Drug Administration (FDA) approved RFID chips for human implantation in 2004.
pick up coffee or hit the gym (hint: avoid Monday after work?""Google's post reads."
Their reward was a small drink of juice. One monkey acting alone could not move the arm in three dimensions
Quarks are the tiny ingredients of subatomic particles such as protons and neutrons, which are made of three quarks.
The 56-year-old dietitian from Syracuse, New york, had to give up bicycling because the disorder affected her balance.
To ice the cake, based on the lab work so far, it appears the material could be manufactured at a commercial scale more easily than other graphite replacement materials,
whenever you needed a little extra juice. So, if the Ara phone is launched, could it be possible to have four times the battery life of a current, conventional cell phone?
Both the solar panels and the food-bearing plants receive enough sunlight to be productive. It would be nice
Forget the food-versus-fuel debate: many of the crops grown in the valley are high-value products that are lucrative,
The bacteria and its food source, calcium lactate, are packed into tiny capsules that dissolve when water enters the concrete cracks.
but with an extra ingredient the ealing agent. It remains intact during mixing, only dissolving and becoming active
and produce spores that can survive for decades without food or oxygen. he next challenge was not only to have the bacteria active in concrete,
In order to produce limestone the bacilli need a food source. Sugar was one option, but adding sugar to the mix would create soft, weak, concrete.
In the end, Jonkers chose calcium lactate, setting the bacteria and calcium lactate into capsules made from biodegradable plastic and adding the capsules to the wet concrete mix.
The secret sauce consists of specially placed rows of bacterial spores dotted onto strips of double-sided plastic tape.
Microcapsules have been used in a variety of applications--for example in pharmaceuticals food flavouring cosmetics and agriculture--for controlled delivery and release but this is one of the first demonstrations of this approach for controlled capture says Jennifer A. Lewis the Hansj rg Wyss Professor of Biologically Inspired Engineering at the Harvard School of engineering
sodium carbonate a k a. kitchen-grade baking soda. The microencapsulated carbon sorbents (MECS) achieve an order-of-magnitude increase in CO2 absorption rates compared to sorbents currently used in carbon capture.
These permeable silicone beads could be sliced a-bread'breakthrough for CO2 capture--efficient easy-to-handle minimal waste
#Robots learn to cook by watching Youtube When it comes to teaching robots how to do things,
and manipulation motions required for cooking by observing what humans do on the Internet.""We chose cooking videos
"But cooking is complex in terms of manipulation, the steps involved and the tools you use. If you want to cut a cucumber, for example,
because the robot had not been trained on some objects, such as tofu.""By having flexible robots, we're contributing to the next phase of automation.
"The beauty of this work is that it can serve as a test bed for clinical trials in a dish,
seeded into a 3d scaffold and nourished with a culture gel full of nutrients to encourage growth.
or the diet but the fact that you have to do them all several times a day every day for the rest of your life,
when food is entering the stomach. It then fires low-level electrical pulses into the vagus nerve to fool the brain into thinking the stomach has no more room.
000 and are reserved usually for patients who don't respond to dieting, or who aren't suitable for more drastic gastric bypass surgery.
When it senses muscle contractions that tell it food is entering the stomach, the pill begins to transmit signals along the nerve to the brain to dampen down appetite.
Tam Fry, of the National Obesity Forum, says:''This technology is going in the right direction.'
If a black hole spins slowly enough, it won't repel its meal as much. In the end, a slow-spinning black hole can eat up more matter than a fast spinner.'
'It's like winning a hot-dog-eating contest lasting hundreds of millions of years.''More research is needed to solve this puzzle of these dazzlingly luminous galaxies.
#Flawed science triggers U-turn on cholesterol fears For decades they have been blacklisted as foods to avoid, the cause of deadly thickening of the arteries, heart disease and strokes.
But the science which warned us off eating eggs along with other high-cholesterol foods such as butter, shellfish,
bacon and liver could have been flawed, a key report in the US has found. Foods high in cholesterol have been branded a danger to human health
since the 1970s a warning that has divided long the medical establishment. A growing number of experts have been arguing there is no link between high cholesterol in food and dangerous levels of the fatty substance in the blood.
Now in a move signalling a dramatic change of stance on the issue, the US government is to accept advice to drop cholesterol from its list of'nutrients of concern'.
'The US Department of agriculture panel, which has been given the task of overhauling the guidelines every five years,
Its Dietary Guidelines Advisory Committee plans to no longer warn people to avoid eggs, shellfish and other cholesterol-laden foods.
The U-turn, based on a report by the committee, will undo almost 40 years of public health warnings about eating food laden with cholesterol.
and saturated fat and focusing concern on sugar as the biggest dietary threat. The Daily mail's GP Martin Scurr predicts that advice will change here in the UK too.
because it's easy to convey to the public that fatty foods like butter, cheese and red meat are furring up their arteries.
In fact there are many other risk factors involved but somehow we've become obsessed with cholesterol.'
'London-based cardiologist Dr Aseem Malhotra, science director of campaign Group action On Sugar, wrote in The british Medical Journal that it was time to'bust the myth of the role of saturated fat in heart disease'.
'He added that the food industry had contributed effectively to heart disease by lowering saturated fat levels in food and replacing it with sugar.
and saturated fat in food to heart disease were tinged with scandal'.
#NSA testing smartphones that can tell who you are by the way you write: Handwriting recongition system The NSA is set to begin using smartphone software that can recognise a person by the way they write.
and fed nutrients and oxygen. In just two to three weeks, the blood vessels and muscles had rebuilt, this week's New Scientist reports.
and codeine from a common sugar, boosting the prospect of'home-brew'drug supply. But whether making morphine in bubbling vats of yeast will be commercially viable-either for drug companies
The cells that carry an alternative genetic code will make them dependent on an artificial nutrient not available in nature.
#Beauty Is Only (3-D Printed) Skin Deep Global cosmetics giant L'oréal has waged a battle against gravity for more than a century, with countless creams, peels and potions as its weapons.
That righthe duo went from high-tech to food scraps, hoping to address the fact that 40 percent of food in the U s. bout $165 billion worth per yearoes uneaten, with most ending up in landfills, according to a 2012 report from the Natural resources Defense Council.
Though the grocery industry recognized the problem, nobody could really explain why it was happening. said,
the Harvester, a machine that, in six to 24 hours, turns food matter into a high-nutrient liquid that can be converted to organic fertilizer.
It works with anything from fish scales and carrot tops to wine. After food waste is converted,
including Whole Foods Market. Its conceptnd early successas helped WISERG secure $14 million from investors,
whether theye tossing more cookies or muffins. That datand the high-quality fertilizeras turned Chapman into a WISERG evangelist. e will put them in as many stores as we possibly can,
restaurant or artisan food maker and get a debit card stocked with dible credits, while helping their favorite business get the money it needs to grow.
and order ingredients online for delivery. The Smartgrill by Lynx, programmable via smartphone, is activated voice to cook on user command
or automatically via a database of more than 200 preprogrammed recipes. Instead of reviewing restaurants, Foodspotting users recommend dishes.
The app is searchable by specific foods. Move over lattes. The hottest hot beverages in Manhattan are the sippable one brothsfrom Brodo single-service window, with add-ins like Calabrian chili oil, shiitake mushroom tea and fermented beet juice.
Enjoyfresh online marketplace allows users to search and sign up for unique off-menu dishes and exclusive events at local restaurants.
The Scio handheld spectrometer instantly analyzes foods and pharmaceuticals at a molecular level; a quick scan provides nutritional info,
determines the ripeness level of produce or authenticates medications. Cold butter meets its match with the Butterup knife.
Your bread will thank you c
#Meet Amelia, the AI Platform That Could Change the Future of IT Her name is Amelia,
and she is the complete package: smart, sophisticated, industrious and loyal. No wonder her boss, Chetan Dube, can get her out of his head. y wife is convinced I having an affair with Amelia,
Dube says, leaning forward conspiratorially. have a great deal of passion and infatuation with her. e not alone.
In the future, though, Schoellhammer hopes he can create the needles out of crystallized sugar. The mpill took an estimated three years to go from concept to prototype
crying about the need for a greater slice of the tax revenue and service fee pie,
If Microsoft can get a piece of that massive pie, all the better for its shareholders. With free access to Office and free upgrades to Windows 10, Microsoft is bowing to market realities.
If you were to introduce permanent magnets into the body, by eating them for example, your bowels would quickly be cinched together
Lest the reader think that this is all just pie in the sky, we should give some hard numbers.
and prior attempts to use DNA to make nanoscale sculpture have required high levels of magnesium salt to keep the final shape from unraveling.
As to why scientists would particularly want to be able to create everything from DNA spheres to DNA Coke bottles,
Maggi case should begin new era of food vigilancea leading food safety official has urged India government to view the recent Maggi noodles affair as the beginning of a new era of food safety vigilance.
and lead in Maggi noodles should initiate a campaign against unhealthy food in general. He also called for greater self-regulation by manufacturers and better awareness among the public about how much food safety testing takes place behind the scenes. he heated discussion on the presence of lead in food products,
kicked off by the Maggi fiasco, should go on, Venkatesh said, adding that Maggi research could achieve
it was concluded that there is a need to have a standardisation on packaging of food products which will bring about rationalisation in terms of costs that can be offered uniformly with the setting of uniform standards in packaging,
#High altitude cooking boosts flavour say Nestlé researchers The team led by Dr Candice Smarrito of the Nestlé Research Centre in Lausanne examined the effects of low pressure such as that found at high altitude on the sensory profile
and lower pressure water boils at just 85°C at 3600m above sea level for example allowing foods to cook more gently
and preserving their volatile compounds such as aromas. lavour is a key driver of food acceptance
and nutrition of food without using artificial additives and enhancers. The study said there were two different ways to cook at low pressure without travelling to high altitudes:
Sous-vide which involves vacuum sealing the food in plastic pouches and immersing them in a water bath at 65-85°C and cook-vide in
which pressure is reduced and controlled by a vacuum pump. ooking in such conditions has been shown to prevent losses of aroma compounds
and moisture leading to food preparations with enhanced juiciness and flavour intensitysmarrito and her colleagues wrote.
They found that sulphur aromas associated with leeks were enhanced particularly by low pressure cooking. ow-pressure cooking could be used advantageously to improve the nonvolatile and volatile composition as well as the sensory profiles of broths (especially regarding the overall intensity leek/onion
and celery/savoury notes) they wrote.?Thus low-pressure boiling might apply to enhance the flavour profiles of culinary preparations
Journal of Agricultural and Food Chemistrypublished online ahead of print. DOI: 10.1021/jf506173mmpact of Boiling Conditions on the Molecular and Sensory Profile of a Vegetable Brothuthors:
#Flavour delivery particle can cut sugar by half and is cheaper than sugar Developed by inventor
and Douxmatok CEO Avraham Baniel-who used to be part of Tate and Lyle's Splenda team-along with the Warner Babock Institute for Green Chemistry,
a carrier particle is coated with sugar molecules using non-covalent bonding. This increases the surface area meaning the same sweetness can be achieved using less sugar.
Joint CEO Eran Baniel told Foodnavigator that because Douxmatok which means twice as sweet in French
and Hebrew-uses sugar, rather than artificial or alternative sweeteners, consumers'taste expectations are satisfied and there are no aftertaste issues. ee not about reformulation.
some corn syrup and mix them up(.In medicine you talk of drug delivery-we do flavour delivery.".
"The sensory profile of Douxmatok is literally the same as sugar.""The carrier particle has been approved for use in food
and beverage applications and requires no regulatory process. Two patents have been granted in the US and two issued in the EU. Taste is king for the consumer cost for the companyat a tasting session in Israel Foodnavigator tried out Douxmatok's tomato ketchup with 54%less sugar,
and Douxmatok peach jam which uses 38%less sugar for the same amount of fruit as a conventional recipe.
While there were some textural differences the Douxmatok products had more body and were slightly darker in colour the sweetness was the same.
But, according to Baniel, this only poses a problem for manufacturers of dark chocolate. Despite reducing the calorie content,
Douxmatok's food technologists found a way to retain the same energy content-an important factor for consumers. obody ever says really tired I need some aspartame for energy!
and this is a very important issue for the industry. f youe the same price as sugar all you get is compliments and nothing else.
and compensating for this loss by increasing other ingredients, such as cocoa in chocolate, could be costly for manufacturers of certain products.
But this is something the R&d team is working to overcome, Baniel said. olume-wise we are big
and teach them how to use the technology as some culinary methods need to be adapeted-Douxmatok's sugar needs to be added to a product at very specific moments
and taste-tested for candy, chocolate, baked and dairy products and pharmaceutical syrups, while a second generation particle called S2 can be used in beverages.
The R&d team is looking into using the technology for salt reduction, while a carrier particle for Xylitol, Malitol and Erithrytol has also been developed
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