"Funders of the work include the Department of defense Breast cancer Research Program, the National institutes of health, the Sidney Kimmel Foundation,
But subsequent work by Prusiner and others led to an understanding of how prions function at a molecular level.
was awarded the Nobel prize in Physiology or Medicine for this work in 1997. Prion researchers have suggested
The new work has its origins in experiments conducted in Prusiner's lab in 2013,
San diego demonstrated a new wireless communication technique that works by sending magnetic signals through the human body.
While this work is still a proof-of-concept demonstration researchers envision developing it into an ultra low power wireless system that can easily transmit information around the human body.
In their experiments, researchers demonstrated that the magnetic communication link works well on the body,
Arraythe breakthrough came after years of meticulous work developing expert knowledge in the field of genetics at Uio and OUS.
"The work by Karatsoreos and his colleagues--published in the journal Brain, Behavior and Immunity--is a rare look into the circadian process,
shift work, jet lag and even the blue-tinged light emitted by cell phones and tablets. Typically, sleep researchers have a hard time studying sleep deprivation and the circadian cycle separately,
if you think of disruption going on for years for somebody who's working shift work, "he said.
complete paralysis has regained enough voluntary control to actively work with a robotic device designed to enhance mobility.
"If the robot does all the work, the subject becomes passive and the nervous system shuts down,
it wasn't just the robotic device doing the work.""For people who are injured severely
"The results of this work may provide additional evidence that eotaxin plays a role in the deleterious effects of aging,
It was designed to assist the work of astronauts in complicated situations, especially during extra-vehicular outings g
Georgia Tech professor Glaucio Paulino and University of Tokyo professor Tomohiro Tachi published their work in the Proceedings of the National Academy of Sciences.
"The zipper configuration works even with tubes that have different angles of folding. By combining tubes with different geometries, the researchers can make many different three-dimensional structures,
She took a library of cells that Dan had developed in his work with bladder cancer
"Right now there is a single antibiotic that works against this parasite. We know that eventually the parasite will develop resistance to the antibiotic
The work was led by Rahul Panat and Indranath Dutta, researchers in Voiland College's School of Mechanical and Materials Engineering,
which works better than other materials but is prohibitively expensive, and copper, which severely cracks when it is stretches more than 30 percent or so.
While Panat is excited about the work and hopes it will be commercialized, the researchers also want to better understand the metal's behavior."
but much work is needed to validate it. It's a good situation to be in
so you want your first therapy to work, "she said.""With this cancer, you don't have a lot of time to try different therapies.
"The allosteric modulators that we have developed work differently. Our molecule is very small, "says enthusiastically Dr. Sylvain Chemtob, a neonatologist and investigator,
But we need to do much more work.""A pharmaceutical hit compound, like those discovered by Vogel
But we need to do much more work.""A pharmaceutical hit compound, like those discovered by Vogel
"The method of inverse epitaxy works for various materials but is still in its basic research phase.
#Researchers work to improve antibiotic effectiveness Virginia Tech researchers have discovered a new group of antibiotics that may provide relief to some of the more than 2 million people in the United states affected by antibiotic resistance.
The group plans to continue its work to refine the device. A research group from Osaka University is collaborating with Mittleman's group to implement the device in a prototype terahertz network they're building."
"Mittleman hopes that the work will challenge other researchers to start developing components for terahertz networks."
the work showcases the new technology and its practical importance in clinical science by showing how it has given new insights into Alzheimer's disease plaques."
The work is currently in its early stages and in future studies the researchers will look to optimise the design of the catalyst
"The collaborative, cross-disciplinary work was supported by the Harvard university Materials Research Science and Engineering Center (MRSEC),
Their work also serves as a foundation for further studies into acetylcholine-related diseases, and may lead to new treatments that involve BNIP-H."Our findings could provide new direction to better understand causes of cholinergic-related diseases, such as Alzheimer's disease, Down's syndrome, ataxia and schizophrenia.
Even when the process works, a high sperm-to-egg ratio is required, the opposite of what occurs in the body."
"Our work may lead to the discovery of genes and gene products that cause infertility,
Their work also serves as a foundation for further studies into acetylcholine-related diseases, and may lead to new treatments that involve BNIP-H."Our findings could provide new direction to better understand causes of cholinergic-related diseases, such as Alzheimer's disease, Down's syndrome, ataxia and schizophrenia.
The novel technique--called Safepay--works by transforming disposable credit card information to electrical current and driving a magnetic card chip to simulate the behavior of a physical magnetic card.
the design of Safepay, prototype implementation and security analysis. Here's how it works: First, the user downloads and executes the mobile banking application
The work was performed at the University Jean Monnet of Saint-Etienne, France, in close collaboration between a team of virologists belonging to the GIMAP group under the supervision of Pr.
The work was published in the Proceedings of the National Academy of Sciences (PNAS. Mixing complex fluids is fundamental for printing a broad range of materials.
This method works well with low-viscosity fluids, but is ineffective with high-viscosity fluids, like gels, especially in small volumes over short timescales.
"The recent work by the Lewis Group is a significant advancement to the field of additive manufacturing,
This work will be foundational for applications which required integrated electrical and structural materials.""Lewis'lab also recently designed another printhead that can rapidly switch between multiple inks within a single nozzle,
"I think this work will create a paradigm shift in how materials are characterized in the 21st century,
Consequently, shining light through a sample leaves the resonant fingerprints in the spectrum allowing identification.
The work, published Monday in the Proceedings of the National Academy of Sciences, pairs gold nanomesh with a stretchable substrate made with polydimethylsiloxane, or PDMS.
This work expands on that, producing the material in a different way to allow it to remain fatigue-free through thousands of cycles s
The work by Shanhui Fan, a professor of electrical engineering at Stanford, research associate Aaswath P. Raman and doctoral candidate Linxiao Zhu is described in the current issue of Proceedings of the National Academy
They presented that work in Nature, describing it as"radiative cooling "because it shunted thermal energy directly into the deep, cold void of space.
In their new paper, the researchers applied that work to improve solar array performance when the sun is beating down.
the ongoing effort to fashion treatments that affect diseased areas but leave healthy tissue alone."
'Proof of principle'"This was a proof-of-principle experiment so there's a lot of work to be done,
"This is terrific work, a beautiful paper, "Langer said.""Dr. Swartz and colleagues have done a remarkable job of stabilizing viruslike particles
but with his latest publication, he knows his work is playing a part. Macdonald, a Canada Research Chair in Islet Biology, associate professor in the University of Alberta's Faculty of medicine & Dentistry and member of the Alberta Diabetes Institute, is the senior author of a landmark study in the Journal of Clinical Investigation.
Next, researchers would like to study how the two-drug approach works in humans, although no clinical trials have yet been designed or scheduled h
and this leaves patients open to recurrence,"Werb said.""Patients have their original tumor treated or removed,
Previous work by Werb's group had found a subset of cells at the edges of breast cancer tumors that seemed primed to metastasize.
we would have said it doesn't work, "she said.""This tells us you actually have to look at metastases
the senior author of a paper describing this work in the Sept. 23 edition of the journal Cell Systems.
Here's how it works: The first participant, or"respondent,"wears a cap connected to an electroencephalography (EEG) machine that records electrical brain activity.
The UW team's work takes a different approach, using technology to strip away the need for such intermediaries."
How Velox works The tiny device comprises a prosthetic heart valve made of pericardial tissue"stitched"within a self-expanding
They hope to work with medical technology companies to commercialise their invention to benefit patients soon n
"He said that a key next step for the project is to identify the right industry partners to work with to manufacture the full-scale quantum processor chip.
The work by Cranston, an assistant chemical engineering professor, and Zhitomirsky, a materials science and engineering professor, demonstrates an improved three-dimensional energy storage device constructed by trapping functional nanoparticles within the walls of a nanocellulose foam.
remarkable ability to organize team work and generate new ideas
#Groundbreaking computer program diagnoses cancer in two days In by far the majority of cancer cases, the doctor can quickly identify the source of the disease, for example cancer of the liver, lungs, etc.
This work is published in PNAS. Many diseases involve structural changes in tissues which are reflected in a change in their mechanical properties, such as elasticity.
something that greatly complicates the work of neurosurgeons. On the other hand, the brain is the seat of natural vibrations created by the blood pulsating in the arteries and the circulating cerebrospinal fluid.
"says Stéfan Catheline, Inserm Research director and main author of this work.""Alzheimer's disease, epilepsy, multiple sclerosis and hydrocephalus involve changes in the stiffness of the brain tissues.
The next stage of the team's work involves working with medical researchers to test the new technology on animals.
"Hasan's method, developed at the University's Nanoscience Centre, works by suspending tiny particles of graphene in a'carrier'solvent mixture,
The same method works for materials other than graphene, including metallic, semiconducting and insulating nanoparticles. Currently, printed conductive patterns use a combination of poorly conducting carbon with other materials, most commonly silver
potentially improving our understanding of how the heart works. The research can also be applied to the physics of such waves in other processes.
The work is detailed in an open-access paper this week in Nature Methods. The ability to identify DNA or RNA sequences,
In previous work, the lab designed probes that find single-nucleotide mutations in DNA while using"competing"probes to bind to healthy sequences
Work from Prof. Gotam Jarori's lab has shown earlier that this protein, enolase, is a protective antigen
The work was carried out in collaboration with Prof. Shiladitya Dassarma's laboratory at the University of Maryland School of medicine, Baltimore, USA, who has developed Archaeal gas vesicle nanoparticles (GVNPS.
and this work is a significant step forward towards a new malaria vaccine.""This study is a significant advance in the field,
What makes this work so groundbreaking is that these genetic modifications look just like genetic variations resulting from the selective breeding that farmers have been doing for millennia.
How the Microscope Works The researchers'device identifies and quantifies lymphocytes, monocytes, and granulocytes--three types of white blood cells--in a drop of blood mixed with the staining compound acridine orange.
Future work for Tkaczyk and his colleagues includes developing an automated algorithm for white blood cell identification,
'The biggest surprise from our work is damaged that mitochondria produce a signal that actively prevents nerve cells from working properly.
or damaged by routine manual work or sports such as rock climbing. Additionally people attempting to escape identification might deliberately thwart the sensors by rubbing out their fingerprints,
and works by analyzing an interference pattern created when a beam of light that travels through a biological sample,
The work, recently published in The Annals of Thoracic Surgery, demonstrated significant benefits of implanting a left ventricular assist device (LVAD) in the right atrium to provide better blood flow through the lungs,
The newly discovered molecule works against glioblastoma by wedging itself in the temporary interface between two proteins
In order to work, transcription factors must buddy up, with two binding to each other and to DNA at same time.
The multidisciplinary team united scientific experts to work in enzyme technology to make visible this marker and use an analytical process;
The researchers are now working on adapting the magnetic sensors to work in mammalian cells. They are also trying to make the engineered ferritin even more strongly magnetic c
In their experiments, the work group of Thomas Jentsch had switched systematically off different combinations of VRAC forming proteins.
We now need to see if this works in more patients and other cancer types,
But this work gives us a window into the future, where we'll use less invasive techniques to track the disease in real time
Previous work in this realm relied on"growing the cell cultures in a Petri dish, which tends to deform the structure,
The significance of the group's work is that it focuses on an unexplored method of measuring the properties of cells
At a stroke, their work expanded the number of known typesr phylaf bacteria by nearly 50 percent,
rendering some organisms effectively invisible. he primers don work as well as people would like them to,
And Kenneth Kam-Wing Lo from the City university of Hong kong says his interesting work will inspire the development of molecular probes and assays for biomolecules with high selectivity and sensitivity.
The work represents n important advance in the development of skinlike materials that mimic the functionality of human skin at an unprecedented level
Thomas Mchugh, a neuroscientist at the RIKEN Brain science Institute in Tokyo, says that he has been following the team work for years
A team at the University of Pennsylvania (Penn) in Philadelphia is taking a different approach to enhancing memory that requires an even less detailed understanding of how the process works.
Although it would be useful from a basic-science viewpoint to discover why stimulation works so well,
this work shows the potential for seamless biotechnological restoration of all function. For now, Darpa is keeping details on the work under wraps pending peer review
and publication of a paper describing it. Although promising, such work remains expensive and firmly limited to the lab. Further,
invasive surgery and wired brain implants are not an ideal solution. And limited to pressure,
With today work laying the foundation, it seems likely additional sensations, like temperature, may be added later.
Mccully and other UGA researchers will continue to work with Georgia Regents University to determine what is keeping cystic fibrosis patients#muscles from properly functioning,
works by blocking a signalling pathway related to a group of cell receptors called Ephb. This means that when used to treat mice with colon tumours
n this work we have begun to crack open the question of why residual disease persists after targeted therapy.
The work, reported this week in Nature, brings fresh optimism to the field of HIV immunotherapy
It requires a little work to translate that description into the syntax of the probabilistic programming language,
What old is new The new work, Kulkarni says, revives an idea known as inverse graphics,
to see which works best. Moreover, Kulkarni says, Picture is designed so that its inference algorithms can themselves benefit from machine learning,
who was involved not in the work. t goes beyond image classification the most popular task in computer vision
#New Way to Fight Cancer Targeted cancer therapies work by blocking a single oncogenic pathway to halt tumor growth.
In this new work, co-senior author Xiao Zhen Zhou, HMS assistant professor of medicine and an investigator in the Division of Translational Therapeutics at Beth Israel Deaconess, decided to take a different
whose own pioneering work revealed the molecular underpinnings of APL and led to its cure. hese new findings demonstrate that by inhibiting Pin1,
and the engineered system works like natural transport proteins found throughout the human body. Rocker was designed to perform this function by doing one thing ockingbetween two different shapes, or conformations.
and give experimentalists a much better set of materials to work with than if they were to explore all possible combinations.
or don work, Persson said. requently we rely on trial and error. If something doesn work, we throw it away
and go to the next thing, but we don understand why it didn work. Having an explanation becomes very usefule can apply the principles wee learned to future guesses.
So the process becomes knowledge-driven rather than trial and error. How it works funnel method The Electrolyte Genome uses the infrastructure of the Materials Project, a database of calculated properties of thousands of known materials,
co-founded by Persson and Gerbrand Ceder of MIT. The researchers apply a funnel idea
Says Study Angiogenesis inhibitors widely used class of cancer drugs designed to shrink tumors by preventing them from forming new blood vesselsften work in the short term,
and are part of the body first-line of defensehe so-called nnateimmune systemt first work in concert with the therapy
leaves harvest solar energy and carbon dioxide is reduced and combined with water for the synthesis of molecular products that form biomass,
Future work may investigate how modifying the Wnt signal can be used to manipulate synaptic plasticity, with possible therapeutic applications for neurodegenerative or mental diseases n
The work of Montgomery, Hafler, and Herold may be just the tip of the iceberg. With this more powerful tool for analyzing cells,
and made it work! explains Professor Nini Pryds. Despite the fact that d-Bismuth oxide is made of just 2 elements (bismuth and oxygen),
The results of this work were patented recently, with the hope that this discovery opens brand new possibilities for usingd-Bismuth as an ion conductor. e have used very advanced fabrication
three long and intense years of work using advance state-of-the-art characterization techniques combined with great team work results in these exciting results continues Dr. Simone Sanna.
We still have some important work to complete including testing the life of the spare laser,
The work was led by Professor John Sader at the University of Melbourne School of Mathematics and Statistics and Professor Michael Roukes of the California Institute of technology.
Blocking other enzymes involved in ATP production prior to the work of ATP synthase however, did not damage egg development. ur team plans further investigations into precisely how ATP synthase biologically controls cristae development,
Azte works with ASU faculty, post-docs and graduate students to help move university inventions from the lab to commercial application. have had many interactions with the very efficient and professional staff at Azte
and Todd and Randy had to do to make sure that it actually works. When extended the telescoping snout locates the KBO mirrors at the end of a Diagnostic Load Package (DLP),
the device works because of the relationship between the frequency of the mirror oscillation and the timing of the positioning of the perfect angle for the incoming X-ray. f you sit on a Ferris wheel holding a mirror,
he said. he Argonne team work is incredibly exciting because it creates a new class of devices for controlling X-rays, added Paul Evans,
a German synchrotron research facility. his work is a very interesting first step of the MEMS application to X-ray optics.
Distinguished Professor of Materials science and engineering at NC State and corresponding author of a paper describing the work.
The last component works as a octor, or ngineer, diagnosing and repairing problems autonomously. e can give the system choices, like, o to either this or that science location and map it out,
As a result of their work Yao and his colleagues uncovered the molecular signaling system that enables theca cells to make androgen.
For future work, Yao wants to explore the two types of cells that make up theca cells.
but also for fighting them. f the method is proven to work, it could also be used to transport therapeutically effective radioactive substances to the tumor
. a biomedical engineer and faculty member at the Center for Nanomedicine at the Wilmer Eye Institute at Johns Hopkins. A report on the work appeared in the Proceedings of the National Academy of Sciences on June 29.
Suk says their work with nanoparticles grew out of failed efforts to deliver treatments to people with lung diseases.
The work is centered on enhancing the arrangement of colloidsmall particles suspended within a fluid medium.
#Words That Work Together Stay together How language gives your brain a break. Here a quick task:
Other scholars who have done research on this topic say the study provides valuable new information. t interesting and exciting work,
Gibson, and Mahowald readily note that the study leaves larger questions open: Does the DLM tendency occur primarily to help the production of language, its reception, a more strictly cognitive function,
and we still have many interesting new approaches. ith this work, George and his team are bringing us closer to a sustainable future in
it leaves the sheet suspended over a hole. t almost like a drumhead, says Xiao-Min Lin,
Previous work by Peter Dedon, Steven Tannenbaum, Gerald Wogan, and James Fox all professors of biological engineering at MIT had identified the presence of a lesion,
he explains. his scenario would best explain the work of James Fox and his MIT colleagues on gastrointestinal cancer.
If this doesn work, the function of the cell is disturbed, resulting in diseases. Having too few invaginations is associated with atrial fibrillation.
This discovery helps us understand how cells work, and provides insight into how to combat diseases caused by a lack of caveolae.
which last passed near the Earth in 1992, leaves such debris in the Earth path.
However, in a tilted lattice, the atoms would have to work against gravity. In this scenario, atoms could only move with the help of laser beams. ow the laser beams could be used to make neutral atoms move around like electrons in a strong magnetic field
and keep them cold some of it was painstaking work. In the end, the researchers were able to keep the superfluid gas stable for a tenth of a second.
hile this work is still in its early stages, it has immense potential to impact education.
and psychology come together. n order for the machine teaching approach to work, it needs a good model of how the learner behaves that is,
Ultimately, we hope that the work can be used to help teachers develop lesson plans and curricula that promote learning in a wide variety of fields,
A two-year seed grant from the UW-Madison Graduate school currently supports this work. Future funding from outside sources will be sought. ith machine teaching it conceptually easy,
Thanks to his latest work, Hubbard is bringing that future closer to reality. Hubbard research, published in the journal Nature Methods, demonstrates a new technology advancing the field of genome engineering.
He hopes his current work will play a role in helping genome engineering reach its full potential
While most of the work described in the study was done in mouse models, the researchers also found similar cells in human livers.
He adds that further studies are necessary to fully understand how the hormone works in humans
However, future refinement of this work should lead to more scalable protocols. piegelman and colleagues have shown unequivocally that the ythicalirisin peptide is produced
also not affiliated with the work. his data should settle the controversy surrounding the existence of irisin and its increase in blood as a function of exercise
The work was completed at Case Western Reserve University (CWRU), Cleveland and was funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB),
he. ur brains work in three dimensions, and treatment planning with a printed model takes on an intuitive feel that it cannot
Xu built on work he did as a postdoctoral researcher at Harvard with Xiaowei Zhuang, who invented STORM, a super-resolution microscopy method based on single-molecule imaging and photoswitching.
and make it work with conventional microscope systems, thus making it more broadly accessible. He is also trying to develop suitable dyes
That work, recently published in the journal Nature Communications, was a collaboration with Emory University Professor Pete Wenner and former graduate student Ming-fai Fong,
#Scientists discover the mechanism behind the innate immunological memory There can be no argument it is extremely important to understand how immunity works.
Semiconductor lasers typically emit into elliptical beams that are really hard to work with and the new metasurface optical components could replace expensive optical systems used to circularize the beams.
#An engineered surface unsticks sticky water droplets The leaves of the lotus flower, and other natural surfaces that repel water
assistant professor of mechanical engineering and a faculty member in the Penn State Materials Research Institute. ur surfaces combine the unique surface architectures of lotus leaves
The authors believe this work will open the search for a new, unified model of wetting physics that explains wetting phenomena on rough surfaces e
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