It s only a matter of time before a movie villain pulling off the crime of the century needs a cutting tool that is harder than anything else On earth.
#Genomes link Aboriginal australians to Indians Some Aboriginal australians can trace as much as 11%of their genomes to migrants who reached the island around 4, 000 years ago from India,
Along with their genes, the migrants brought different toolmaking techniques and the ancestors of the dingo, researchers say1.
"Australia is thought to represent one of the earliest migrations for humans after they left Africa,
Irina Pugach, a postdoctoral researcher in Stoneking s laboratory, discovered signs of the Indian migration by comparing genetic variation across the entire genomes of 344 individuals, including Aboriginal australians from the Northern territory, highlanders
Pugach confirmed an ancient association between the genomes of Australians New Guineans and the Mamanwa#a Negrito group from the Philippines.
suggesting that they all descended from an early southward migration out of Africa. But Pugach also found evidence of more recent genetic mixing,
This gene flow could not have occurred during the initial wave of migration into Australia because it is absent from New Guinean and Mamanwa genomes,
All of these changes may be related to the same migration, the researchers say.""There have been very few genetic studies of Australians,
She believes that the Aboriginals'vast genetic diversity suggests that multiple waves of migration could have occurred,
The high court s refusal to consider an appeal in the case of Sherley v. Sebelius ends a more than 3-year effort by the plaintiffs, two adult-stem-cell researchers,
from leftover embryos at fertility clinics that would have been thrown away. The NIH does not fund the derivation of the lines, only the subsequent research.
but it is not the essential master regulator of memory that the current literature suggests it to be,
and some flouted orthodoxy by blocking other RNA strands from being translated into protein. But almost all were linear.
US guidelines set by the Adult Treatment Panel (ATP) have lowered gradually acceptable levels for LDL bad cholesterol,
babies born up to three months before full term can already distinguish between spoken syllables in much the same way that adults do,
What is more, the parts of the cortex used were the same as those used by adults for sophisticated understanding of speech and language.#
All three planets keep closer to the star Kepler 37 than any planet orbits the sun."It just shows that Kepler has just an extraordinary ability to see a wide diversity of planetary architectures,
manufacturers could grow cell cultures in which key genes are turned off until activated by a signal compound, permanently turning on production of a drug, for example,
It is also causing more serious illness and deaths than usual, particularly among the elderly,
when they or someone in their family are experiencing symptoms of ILI. Flu Near You, a system run by the Healthmap initiative co-founded by Brownstein at Boston Children s Hospital,
#Small-molecule drug drives cancer cells to suicide Cancer researchers have pinned down a molecule that can kick-start the body s own tumour-destroying systems,
triggering cell death in cancerous but not healthy tissue in mice. The molecule, TIC10, activates the gene for a protein called TRAIL (tumour-necrosis-factor-related apoptosis-inducing ligand),
It was especially effective at triggering cell suicide in glioblastoma, a kind of brain tumour that is notoriously difficult to treat2.
which apoptosis#or cell death#is induced in cancer cells immediately next to healthy ones. Healthy cells are stimulated also to increase the amount of TRAIL receptors on their cell surface.
This is by no means the only mechanism thought to trigger cell death in cancer. In particular, cancer researchers have been developing a number of drugs,
Depositing human embryonic stem cells in cultures using a 3-D printer offers some advantages.
it could also be used to create vaccines for human diseases that are caused by viruses of the same family, such as hand, foot and mouth disease,
But in the past three years scientists have made some progress mapping the transporters detailed architecture. Two different labs have revealed already the structures of two bacterial MATE proteins,
because they establish the overall architecture, he says. Nureki and his team also identified a peptide#a short string of amino acids#that inhibits the MATE protein they studied
says James Turk, executive director of the Canadian Association of University Teachers in Ottawa, Ontario.""There is a consistent pattern of steering money away from basic research,
The connection has earned the 2b the nickname of death receptor. The researchers also investigated how differences in binding affected chemical cascades.
says Michel Sadelain, a researcher at the Memorial Sloan-Kettering Cancer Center in New york and an author of the study.
By the time the man started the trial, 70%of his bone marrow was tumour. Brentjens, Sadelain and their colleagues then extracted T cells from the patient
and identify mutations that might be causing the undiagnosed diseases that afflict his clients families.
"I don t think there are red flags but I do think there are yellow flags. Her main concern is one of scale."
in colonies of up to 12,000 adults. They typically build their conical, mud-based nests into the sides of cliffs,
and stuffing#gathering 104 vehicle-killed adults and 134 adults killed accidentally in nets used for the study.
When he and Bomberger Brown noticed a decline in the annual number of roadkills #even though the overall population was compared increasing#they the wing measurements of both types of stuffed bird.
"It is a bright star now in the literature, suggesting that it is not crazy to map every neuron in the brain of an animal.
and a detector captures the signals like a viewer watching a cinema screen. The system records activity from the full brain every 1. 3 seconds.
She thinks that traditional virus-hunting techniques failed to find TDAV because they rely on strong similarities to known viruses,
or on the ability to culture the mystery culprit. By contrast, her team sequenced everything in their samples#an approach"that meant we didn t have to know what we were looking for,
After all, human hepatitis can be caused by at least five viruses. TDAV belongs to the family Flaviviridae,
and associations in big data might be a necessary incubation step for formulating well-defined hypotheses. On this platform, the researchers reconstructed a large-scale simulation of human brain activity in a 3d virtual reality environment.
and gel density and optimizing the culture matrix and media to make this work with human muscle cells,
These biomimetic constructs exhibit aligned architecture, multinucleated and striated myofibers, and a Pax7+cell pool.
During culture, myobundles maintain functional acetylcholine receptors and structurally and functionally mature, evidenced by increased myofiber diameter and improved calcium handling and contractile strength.
Chief Scientist for The ALS Association. he fact that TBK1 accounts for one percent of ALS adds significantly to our growing understanding of the genetic underpinnings of the disease.
, the Åke Wiberg Foundation and the Clas Groschinsky Memorial Fund s
#Molecular Inhibitor Breaks Cycle That Leads to Alzheimer's A molecular chaperone has been found to inhibit a key stage in the development of Alzheimer disease and break the toxic chain reaction that leads to the death of brain cells, a new study shows.
The research provides an effective basis for searching for candidate molecules that could be used to treat the condition.
While some recent AD genome-wide association studies (GWAS), which search the entire human genome for small variations,
other studies have found no association. In comparison, a number of studies have found a strong association between MAPT and other neurodegenerative disorders,
such as PD. hough a tremendous amount of work has been conducted showing the involvement of the tau protein in Alzheimer disease,
The recent association of genetic variation in the MAPT gene with AD risk and the emerging availability of tau imaging are now leading to a recognition that perhaps tau changes are key in the pathophysiologic pathway of AD
the National Institute of General Medical sciences (GM62142), the American Heart Association (11post7380034), the Johns Hopkins Post-Baccalaureate Research Education Program, the International Fulbright Science and Technology Award,
It is progressive#impairing memory destroying motor skills and eventually causing death. The U s. Centers for Disease Control and Prevention estimates 5. 3 million Americans currently have Alzheimer s disease
Some genes have been identified in families however 95 percent of cases are#sporadic#with no link to a gene or family history of Alzheimer s.
Researchers have known long about disease-related protein accumulations (called amyloid plaques) in the brains of Alzheimer s patients.
This study received support from the National institutes of health (MH076145 and T32 DA07315 T32 AG 000216) and the Shaffer Family Foundation.
000 times slower per pixel, says George Church, a professor of genetics at Harvard Medical school who was not part of the research team.
Did some person a woman you thought you knew really well? did that someone racist post on Facebook really stick in your craw
According to the press release, uscle progenitors were injected directly into the matrix sheaths that define the position of each muscle. he leg was left to culture in a bioreactor for five days.
that we can culture the entire construct over prolonged periods of time, and that we can repopulate the vascular system
#Pakistan Heatwave Death Toll Passes 1, 000 The death toll from Pakistan killer heatwave rose past 1, 000 on Thursday, with more fatalities expected,
and dehydration. 16 U s. Weather Photos that Will Amaze Youhe death toll is more than 1,
it is illegal for Muslims to eat or drink in public during daylight hours in Ramadan.
The majority of the deaths in Karachi have been among the elderly, the poor and manual labourers who toil outdoors,
Doctor Qaiser Sajjad of the Pakistan Medical Association in Karachi said that a lack of understanding of heatstroke among the public how to spot symptoms
and treat them had contributed to the deaths. he main reason was a lack of awareness among the public no one knew how to cope in such a situation,
and can aid in evaluating heart drugs for safety, particularly for pregnant women. The tiny hearts could also serve as models to treat damaged hearts.
Despite all the tech that is already out there, they hope to increase the connectivity between car and man.
"Mapping man with machine provides an interesting investigation of control, he said, "We think the data might show a different view of who's really driving."
particularly among pregnant women. The researchers are now preparing a larger scale trial for the $34 device,
But the Korean patient appears to have infected at least 22 family members, health care workers, and fellow patients at a hospital where he was treated from 15 may to 17 may.
Alerted by the Korean government that the man had been in close contact with a MERS patient,
Researchers could identify which individual cellsrom a tumor or a strain of bacteriaurvive a drug treatment and study them further, something that's not possible with current culture-and-stain tests,
who was involved not in the study. he importance of this work cannot be underestimated as the world population is aging rapidly. ultiple groups of scientists have shown that adding the blood of older mice to younger animalsbodies makes them sluggish, weaker,
the adults produced lanosterol and had no cataracts. So the researchers wondered: What if lanosterol helped prevent
China has partnered also with a Luxembourg-based firm called Luxspace to send a tiny spacecraft called the Manfred Memorial Moon Mission around the moon.
and a governor of the Association of British Investigators says the notion of space-based detection is fascinating.
A new project proposing that galaxy-spanning alien civilisations should generate detectable heat has turned up a few dozen galaxies that hold promise as harbours for life.
what alien civilisations may be like. This approach is very different says Franck Marchis at the SETI Institute in California who was involved not in the project.
because it doesn't put any constraints on the origin of the civilisation or their willingness to communicate.
Could that mean we have already found alien civilisations that have spread across galaxies? If by'found them'you mean that WISE detected the waste heat from them then yes that's right
if these sorts of energy-hungry civilisations exist WISE should have detected them Wright says. But identifying them is another story.
and galaxies that raised the infrared flag in the WISE survey and figure out if there are more ordinary processes at work.
#Crystal cocoons kept bacteria safe in space ASTEROIDS have a killer reputation taking the blame for death and destruction on massive scales.
when the movement of the wind's particles is perpendicular to the sun's magnetic field they resemble a fluid with sections that are smooth interrupted by bursts of violence.
#NASA orbiter will use laser to bring broadband to moon The man in the moon is about to get his own version of a broadband connection as well as a visit from China.
We've never taken a picture of it IBEX mission scientist Eric Christian said today in a teleconference.
and paint a picture of the solar system using atoms instead of light Christian says. One surprise is that
As an alternative says Sarri the beams can be used to mimic the way particle fountains from black holes
The capsule will carry two men Nie Haisheng and Zhang Xiaoguang and one woman Wang Yaping.
and allowing them to keep growing until they were massive enough to overcome the death spiral.
when it reached a 5-kilometre-high mound of layered sediments in the middle of the crater.
when it reached a 5-kilometre-high mound of layered sediments in the middle of the crater.
Curiosity will keep heading for the layered sediments in the crater's central mound officially named Aeolis Mons
Interdisciplinary approachthe Institute-wide CPI will bring together scholars from three key disciplinary pillars: engineering social science and management.
The Foundation concentrates its resources on activities in education the environment global development and population performing arts and philanthropy as well as grants to support disadvantaged communities in the San francisco bay Area.
Furthermore the authors of the Nature Communications paper show that incorporation of Rajca s nitroxide in Johnson s branched bottlebrush polymer architectures leads to even greater improvements in the nitroxide lifetime.
Sociometric s MIT cofounders and co-inventors of its technology include Alexander Sandy Pentland the Toshiba Professor of Media Arts
and academic component to MIT and adds an important pillar to the formal strategic partnership announced by MIT and MGH last month.
Until recently, Spielberg worked in the MIT Media Lab with Neri Oxman, the Sony Corporation Career development Assistant professor of Media Arts and Sciences, graduate students Steven Keating and John Klein,
Nonetheless, he a member of a recently formed rock band with a fellow mechanical engineering major and two computer science majors, keeping music
and music that offer a form of self-expression that sometimes hard to attain in other forms of work,
The AMO technology was a new transmitter architecture where algorithms could choose from different voltages needed to transmit data in each power amplifier
We re showing we get much higher degrees of tumor cell death when we deliver the drug locally.
The research was supported by the U s. Department of energy the MIT Energy Initiative and the Chang family y
and has the additional benefits of absorbing sunlight from a wide range of angles and withstanding extremely high temperatures.
you might think of the popular science-fiction films inority Report (2002) or ron Man (2008). In those films, the protagonists use their hands
and, in 2008, for Jon Favreau ron Man, which both depicted similar technologies. Seeing this technology on the big screen inspired Underkoffler to refine his MIT technology,
#Neuroscientists reverse memories emotional associations Most memories have some kind of emotion associated with them: Recalling the week you just spent at the beach probably makes you feel happy
Furthermore the researchers found that they could reverse the emotional association of specific memories by manipulating brain cells with optogenetics a technique that uses light to control neuron activity.
Previous research has shown that many aspects of memory including emotional associations are malleable. Psychotherapists have taken advantage of this to help patients suffering from depression
when their hippocampal cells were activated showing that a pleasant association had replaced the fearful one. This reversal also took place in mice that went from reward to fear conditioning.
This suggests that emotional associations also called valences are encoded somewhere in the neural circuitry that connects the dentate gyrus to the amygdala the researchers say.
and amygdala cells that encode positive associations. That plasticity of the connection between the hippocampus and the amygdala plays a crucial role in the switching of the valence of the memory Tonegawa says.
the team analysis shows that the lead from a single car battery could produce enough solar panels to provide power for 30 households.
Plasmodium falciparum a blood-borne parasite carried by mosquitoes is responsible for most of the estimated 219 million cases and 655000 deaths from malaria per year.
Melanie Gonick/MIT Instead she and Zhu chose to manufacture an array of microscopic pillars that uniformly tilt in response to a magnetic field.
and bonded the nickel pillars to a soft transparent layer of silicone. The researchers exposed the material to an external magnetic field placing it between two large magnets
and found they were able to control the angle and direction of the pillars which tilted toward the angle of the magnetic field.
and the pillars will follow the field in real time Zhu says. Tilting toward a fieldin experiments the team piped a water solution through a syringe and onto the microhair array.
which the pillars tilted while being pinned highly or fixed in all other directions#an effect that was seen even
Through a combination of surface tension and tilting pillars water climbed up the array following the direction of the pillars.
while tilting the pillars at various angles and found she could control how much light passed through based on the angle at which the pillars bent.
In principle she says more complex magnetic fields could be designed to create intricate tilting patterns throughout an array.
Or depending on how you design the magnetic field you could get the pillars to close in like a flower.
Joining him on the paper are Ramesh Raskar the NEC Career development Professor of Media Arts and Sciences and director of the Media Lab s Camera Culture group and Berkeley s Fu-Chung
The display is a variation on a glasses-free 3-D technology also developed by the Camera Culture group.
They could also reproduce another Camera Culture project which diagnoses vision defects. So the same device could in effect determine the user s prescription
This could lead for example to more relevant online ads as well as enhanced gaming and online learning experiences.
and is resolved not by end that s a red flag el Kaliouby says. Affectiva has been working with advertisers to optimize their marketing content for a couple of years.
and families working together to achieve it. This is a pivotal moment says Thomas Insel director of the National institute of mental health (NIMH.
and a needed parallel effort to increase resources for services that can help patients and their families.
Sharing code not data The example I like to use is personalized music says Yves-Alexandre de Montjoye a graduate student in media arts and sciences and first author on the new paper.
De Montjoye is joined on the paper by his thesis advisor Alex Sandy Pentland the Toshiba Professor of Media Arts and Sciences;
you may want your family to be able to share the pictures you post on a social-networking site.
What their quality of life? There are people who work on those buildings. We can provide them with better information to do their jobs,
and MIT professors of architecture Les Norford and Leon Glicksman and about a dozen companies now operate in the field.
flat-screen TVS, gaming consoles, laptops, electric bikes, and air conditioners, while reducing the cost of manufacturing.
Ramesh Raskar, an associate professor of media arts and sciences at MIT and an author of this paper, has worked extensively on developing this type of 3-D imaging.
#Glasses-free 3-D projector Over the past three years, researchers in the Camera Culture group at the MIT Media Lab have refined steadily a design for a glasses-free, multiperspective, 3-D video screen,
and Ramesh Raskar, the NEC Career development Associate professor of Media Arts and Sciences and head of the Camera Culture group built a prototype of their system using off-the-shelf components.
but by tailoring their algorithm to the architecture of the graphics processing units designed for video games,
The BAT could also provide power to places blacked out by natural disasters as well as at amusement parks festivals and sports venues.
considers the new findings very important contribution to the singlet fission literature. Via a synergistic combination of modeling, crystal engineering,
The researchers will present their work at the annual meeting of the Association for Computational linguistics in June.
which is caused by the death of dopamine-generating cells. Jasanoff lab is also working on sensors to track other neurotransmitters,
and Exposition, cosponsored by IEEE and the Power Sources Manufacturers Association. Taking home the infrastructure and resources prize was another MIT team, ulink,
It an architecture influenced by Silver graduate years in MIT Engineering Systems Division, which stresses reliability, scalability,
while providing customers with the option to expand at low cost via a modular architecture. Moreover, though, Ecovolt is automated,
#Bionic ankle'emulates nature'These days Hugh Herr an associate professor of media arts and sciences at MIT gets about 100 emails daily from people across the world interested in his bionic limbs.
At least among amputees Herr says Biom could help by fitting elderly populations with leg prostheses equal in biomechanical agility and control to a young adult s legs:
so that energy losses during exciton migration are limited. The work was supported by the U s. Department of energy and by the National Science Foundation and used facilities of the Eni-MIT Solar Frontiers Center r
or consumers. conomists tend to think what drives international price differences are things like transportation costs, information costs, tariffs, cultural differences, and other factors,
This work shows that CRISPR can be used successfully in adults and also identifies several of the challenges that will need to be addressed moving forward to the development of human therapies says Charles Gersbach an assistant professor of biomedical engineering at Duke university who was not part of the research team.
This approach is an important contribution to efforts to create a arts listfor the retina,
Other methods such as immunoassays, cultures, or polymerase chain reactions (PCR, which copies DNA) may be efficient in one area,
#How tumors escape About 90 percent of cancer deaths are caused by tumors that have spread from their original locations.
Additional benefits to the system Hynes says include reducing brake wear and maintenance and the time employees spend filling up at gas stations.
and now account for 70 percent of cancer mortality worldwide. Early detection has been proven to improve outcomes
The diagnostic which works much like a pregnancy test could reveal within minutes based on a urine sample
so they could be analyzed on paper using an approach known as a lateral flow assay the same technology used in pregnancy tests.
or had a family member with the disease. Eventually she would like to see it used for early detection throughout developing nations.
and Technology Leadership Program was launched a year ago to help members of the Tibetan diaspora find solutions to the challenges they face in some of India s poorest regions.
This program he says is not only Buddhism not only science not only leadership but the three things together.
while gaining exposure to the culture and mentality of the young Tibetans and monks who see things a different way.
and is used now by at least 70 percent of households in the country In a new paper published in the American Economic Review,
William Jack of Georgetown University, show that income shocks force households without access to M-PESA to reduce their consumption by 7 percent more than households in the M-PESA network.
an associate professor of applied economics at the MIT Sloan School of management. heye more likely to get money from their friends and family,
In all, about 50 percent of households in the study reported serious negative income shocks in the six months preceding the survey. hey face very high-risk environments
Suri says. hey also don have government programs like unemployment insurance or health insurance, and they don have private insurance either.
So use of M-PESA has flourished, up from 43 percent of households two years ago.
000 households in areas representing 92 percent of Kenya population. And they uncovered additional geographic patterns about the electronic money transfers:
of mobile technologies. t's intriguing to observe that this cost reduction allows families and friends to virtually fully insure themselves against negative events from crop failure to health shocks
and $3, 000 for further prototyping, the four-man team co-founded Atlas Devices in Boston to develop
soliciting the APA to help maintain the scoreboard above the pool in the Zesiger Sports and Fitness Center.
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