Malaria Diagnosis to Smartphones Researchers at Texas A&m University have developed a novel point-of-care device for field-based diagnosis of malaria using a smartphone.
Once visualized, the nurse can make a diagnosis or capture photos of the patient cervix and transmit them securely to a physician for further analysis. Mobileodt smartphone application supports annotation of these images and transmission of final recommendations by the remote physicians s
sensitive and low-cost diagnosis of many diseases, including HIVNEW research may revolutionize the slow, cumbersome and expensive process of detecting the antibodies that can help with the diagnosis of infectious and autoimmune diseases such as rheumatoid arthritis and HIV.
An international team of researchers have designed and synthetized a nanometer scale DNA"machine "whose customized modifications enable it to recognize a specific target antibody.
#Portable Nanosensors Help Early Diagnosis of Breast cancer Tumors The nanosensor will be able to help the early diagnosis of breast cancer tumors even at very tiny dimensions after the completion of tests
The aim of the research was to facilitate the diagnosis of cancer tumors, including breast cancer, without the need for advanced clinical devices.
and simulated in this research for the early and easy diagnosis of breast tumors. The nanosensor consists of plasmonic nanoparticles that are placed at regular distance from each other.
short of a biopsy, there are few ways to see if a treatment has been taken up by a cancer.
New Option to Diagnose Leukemia Iranian researchers from Tarbiat Modarres University designed a biosensor that enables the early diagnosis of leukemia in the test sample by using naked eyes.
and their application has been evaluated in the diagnosis of the disease. The presence of some proteins in biological liquids of humans (blood
Diagnosis tests are very time-consuming, expensive and difficult in some cases. For example, common methods to diagnose lysozyme protein are Turbidity Meter, Lyso-rocket electrophoresis and ELISA.
The system designed in this research is complicated less in comparison with other diagnosis methods, and it is available,
#Quick, easy and early diagnosis with rare earth ions Lack of oxygen in cells is an indicator of diseases as serious as cerebral haemorrhages, stroke and cancer.
cumbersome and expensive process of detecting the antibodies that can help with the diagnosis of infectious and autoimmune diseases such as rheumatoid arthritis and HIV.
cumbersome and expensive process of detecting the antibodies that can help with the diagnosis of infectious and autoimmune diseases such as rheumatoid arthritis and HIV.
In an intensive care setting, the technology has the potential to be used to make an early diagnosis of locked-in syndrome (LIS),
in Alzheimer disease, there is no tumor to biopsy, Bredesen said. o how do we get an idea about
Dr. J. Jay Gargus, Ian Parker and colleagues at the UCI Center for Autism Research & Translation examined skin biopsies of patients with three very different genetic types
which impedes diagnosis and, ultimately, drug development. There simply may be too many targets, each with too small an effect.
in order to make a diagnosis or prescribe further tests, it is palpation. By its nature, however, the brain cannot be palpated without using a highly invasive procedure (craniotomy,
it could be used in the early diagnosis of brain tumours or Alzheimer disease. This work is published in PNAS.
and could be used to avoid brain biopsies. his method for palpating the brain could have other areas of application,
and diagnosis. Catheline hopes his technique will eventually help doctors diagnose diseases and monitor the success of their treatment.
when mutated, may contribute to an ASD diagnosis-tend to have fewer mutations than most genes in the human gene pool.
About 7 percent of infected people die within 30 days of diagnosis. Treatments for C. difficile infection include fecal transplants,
and up to 12 hours from testing to confirmed diagnosis The test provides rapid, inexpensive, accurate detection of Ebola viral antigens based on colour change within 30 minutes in individuals
and up to 12 hours from testing to diagnosis. While Hallisey wasn able to test her invention on real Ebola patients or virus,
It would also reduce the number of unnecessary and invasive biopsies stemming from the less precise PSA test that's now used."
but it produces so many false-positive results--leading to painful biopsies and extreme treatments--that one of its discoverers recently called it"hardly more effective than a coin toss."
"Our vision is to develop an array of blood tests for early detection and diagnosis of all major cancer types,
simplifying the diagnosis of many bacterial and respiratory infections. The new platform is the latest in a progression of paper-based screening technologies
or muscle weakness, these children had undergone extensive, expensive and invasive testing--often over many years--without a successful diagnosis,
"said Dr. Bernes, whose young patients'previous tests included muscle biopsies, EMG, MRI, EKG and limited gene sequencing."
low-cost molecular tumor diagnosis A device developed by Massachusetts General Hospital investigators may bring rapid,
accurate molecular diagnosis of tumors and other diseases to locations lacking the latest medical technology.
"The device the team has developed--called the D3 (digital diffraction diagnosis) system--features an imaging module with a battery-powered LED light clipped onto a standard smartphone that records high-resolution imaging data with its camera.
The investigators then conducted analysis of cervical biopsy samples from 25 women with abnormal PAP SMEARS--samples collected
along with those used for clinical diagnosis--using microbeads tagged with antibodies against three published markers of cervical cancer.
Based on the number of antibody-tagged microbeads binding to cells, D3 analysis promptly and reliably categorized biopsy samples as high-risk, low-risk or benign, with results matching those of conventional pathologic analysis
. D3 analysis of fine-needle lymph node biopsy samples was accurately able to differentiate four patients
whose lymphoma diagnosis was confirmed by conventional pathology from another four with benign lymph node enlargement. Along with protein analyses, the system was enhanced to successfully detect DNA--in this instance from human papilloma virus--with great sensitivity.
whether ASRGL1 also can be used for diagnosing tissue biopsies taken before the operation, to identify patients in need of more extensive surgery.'
and early diagnosis,"said Ole A. Andreassen, MD, Phd, a senior co-author and professor of biological psychiatry at the University of Oslo in Norway."
But exercise stress testing is inappropriate for diagnosis in hemodialysis patients who have multiple complications including muscle weakness, osteoporosis and peripheral arterial disease."
But exercise stress testing is inappropriate for diagnosis in hemodialysis patients who have multiple complications including muscle weakness, osteoporosis and peripheral arterial disease."
CD4+T lymphocyte capture and detectionaccurate CD4+T cell count is essential for HIV-1 diagnosis and treatment monitoring.
The genetic mutations in the organoid cultures closely matched those in the corresponding tumor biopsies and agreed well with previous large-scale analyses of colorectal cancer mutations.
Early diagnosis is an important part of our overall efforts against this aggressive cancer, alongside developing new treatments to tackle the disease once diagnosis is made.
It underlines the importance of increased research efforts to help improve survival rates.""Many of the urine samples from healthy individuals tested by Tanja's team were donated from the charity's own supporter community,
Easily accessible from nasal biopsies, these cells--which belong to nerve tissues and can differentiate into neurons--constitute an interesting model to identify the genes
Early diagnosis could save lives and reduce healthcare costs. With this motivation in mind, a team of researchers in Germany and Ireland set out to speed up the detection process for bacteria that cause urinary tract infections.
The speedy diagnosis marks a tremendous reduction in the wait time compared to the lengthy lag--often 24 hours
such as dilated cardiomyopathy, we now have both a cause and a diagnosis, and we can initiate treatment right away."
"Avoiding a'fishing expedition'"Not having that result delays diagnosis and increases costs because you're going through a whole bunch of tests--sometimes it becomes a fishing expedition,
which means early diagnosis is vital for a good prognosis. The current diagnostic tools of examination by doctors followed by biopsy inevitably leads to many unnecessary invasive excisions."
"This simple, accurate, in vivo distinction between malignant melanoma and atypical moles may lead to a substantial reduction in the number of biopsies currently undertaken
#Turning breath into words: New device unveiled to give paralysis victims a voice A new device
In an intensive care setting, the technology has the potential to be used to make an early diagnosis of locked-in syndrome (LIS),
"You take a biopsy of those cells, you put it into this device, grow them and see how they respond to different treatments
Unlike Parkinson's patients, who often live 10 to 20 years after their diagnosis, MSA patients typically die within five to 10 years
accurate diagnosis. While polarized light has been preferred the option for malaria detection due to its increased sensitivity,
complexity and lack of expertly trained technicians can often prohibit the use of a polarized microscopy technique or even traditional laboratory microscopy as the standard of diagnosis,
Researchers can learn a lot by analyzing CNVS in bulk samples--from a tumor biopsy for example--but they can learn more by investigating CNVS in individual cells."
"Cancer patients often present with muscle wasting even prior to their initial cancer diagnosis, ''says Dr. Antonio Vigano, director of the cancer rehabilitation program and cachexia clinic at the MUHC."
which--on the basis of a biopsy from a metastasis--can with 85 per cent certainty identify the source of the disease
"We are pleased very that we can now use the same sequencing data together with our new algorithms to provide a much faster diagnosis for cancer cases that are difficult to diagnose,
and to provide a useful diagnosis in cases which are currently impossible to diagnose. At the moment, it takes researchers two days to obtain a biopsy result,
but we expect this time to be reduced as it becomes possible to do the sequencing increasingly faster.
and can analyse a biopsy from a metastasis, and on this basis provide a number of possible scenarios for where the cancer may have developed
analysing a biopsy takes two days s
#Medical diagnosis: Will brain palpation soon be possible? If there is one technique used by the physician to explore the human body during every medical examination
in order to make a diagnosis or prescribe further tests, it is palpation. By its nature, however, the brain cannot be palpated without using a highly invasive procedure (craniotomy,
Ultimately, it could be used in the early diagnosis of brain tumours or Alzheimer's disease. This work is published in PNAS.
and could be used to avoid brain biopsies.""This method for palpating the brain could have other areas of application,
short of a biopsy, there are few ways to see if a treatment has been taken up by a cancer.
"In one of many successful tests, the lab designed molecules to detect mutation sequences in historic biopsy samples preserved in wax from cancer patients.
usually survive fewer than 15 months following diagnosis . Since there are no effective treatments for the deadly disease, University of California,
and will be used for diagnosis within low-income populations. A device that detects in saliva a biological indicator of a possible risk of TYPE II DIABETES is the development of a technological and scientific team of the Tec de Monterrey (Mexican University) in collaboration with the University of Houston.
Over three years, researchers at the University of Cambridge took surgical tumour samples (biopsies) and blood samples from a patient with breast cancer that had already spread to other parts of her body.
comparing them with DNA from the biopsy that was taken at the same point in time. The results show that the DNA in the blood samples matched up with that from the biopsies,
reflecting the same pattern and timing of genetic changes appearing as the cancer developed and responded to treatment.
as taking a biopsy can sometimes be quite an invasive procedure.""The patient in the study had had breast cancer that already spread to a number of other organs.
"For now, surgical biopsies still play an important role in diagnosing and monitoring cancers. But this work gives us a window into the future,
it is easier to administer than traditional methods to measure muscle capacity, such as MRIS or biopsies.#
A major challenge of ASD diagnosis and treatment is that the neurological condition which affects 1 in 68 children in the United states,
They found that pre-diagnosis fmri response to speech in ASD toddlers with relatively good language outcomes was highly similar to non-ASD comparison groups with robust responses to language in superior temporal cortices,
The measurements would help in the diagnosis and treatment of a variety of ocular surface disorders particularly in detecting
Azte really is a helpful resource we have here at ASU. r. La Belle promising technology has the potential to improve the diagnosis
lost contact with NASA. here were human operators On earth who were experts in diagnosis and repair,
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR), in cooperation with colleagues at the University of Zurich and the Ruhr-Universität Bochum, have tested for the first time successfully a new tumor diagnosis method under near-real conditions.
while the most detailed information about how well a treatment is working comes from pathologistsexaminations of tissue taken in biopsies.
and the invasive nature of biopsies makes them a risky procedure that clinicians try to minimize.
Now, researchers at MIT Koch Institute for Integrative Cancer Research are closing that information gap by developing a tiny biochemical sensor that can be implanted in cancerous tissue during the initial biopsy.
is small enough to fit into the tip of a biopsy needle. It contains 10 microliters of chemical contrast agents typically used for magnetic resonance imaging (MRI)
without any diagnosis other than udden infant death syndrome'says Karl Swärd and Catarina Rippe, researchers at Lund University.
which can accurately detect malignant melanoma without a biopsy. The report, published online in Nature Scientific Reports yesterday (August 11),
which means early diagnosis is vital for a good prognosis. The current diagnostic tools of examination by doctors followed by biopsy inevitably leads to many unnecessary invasive excisions. his simple, accurate,
in vivo distinction between malignant melanoma and atypical moles may lead to a substantial reduction in the number of biopsies currently undertaken. ource:
Lancaster Universit L
#Nicotine-eating bacteria could one day help smokers kick the habit Most people who smoke cigarettes know it bad for their health,
so that the diagnosis of heart conditions such as coronary heart disease or arrhythmia can be improved greatly. In the future, a special shield room for detecting the bio-magnetic field would be unnecessary
Kilian said. ou take a biopsy of those cells, you put it into this device,
Dr. J. Jay Gargus, Ian Parker and colleagues at the UCI Center for Autism Research & Translation examined skin biopsies of patients with three very different genetic types
which impedes diagnosis and, ultimately, drug development. There simply may be too many targets, each with too small an effect.
claims Chiu. nbiased point-of-care testing for pathogens by rapid metagenomic sequencing has the potential to radically transform infectious disease diagnosis in both clinical and public health settings.
and making a diagnosis can be an exhaustive exercise, at times requiring a battery of different tests.
We think the test will be especially useful in situations where a diagnosis remains elusive after standard testing or in situations in
and created a new diagnostic technology based on advanced self learning computer algorithms whichn the basis of a biopsy from a metastasisan with 85 per cent certainty identify the source of the disease
e are pleased very that we can now use the same sequencing data together with our new algorithms to provide a much faster diagnosis for cancer cases that are difficult to diagnose,
and to provide a useful diagnosis in cases which are currently impossible to diagnose. At the moment, it takes researchers two days to obtain a biopsy result,
but we expect this time to be reduced as it becomes possible to do the sequencing increasingly faster.
in order to make a diagnosis or prescribe further tests, it is palpation. By its nature, however, the brain cannot be palpated without using a highly invasive procedure (craniotomy,
Ultimately, it could be used in the early diagnosis of brain tumours or Alzheimer disease. This work is published in PNAS.
and could be used to avoid brain biopsies. This method for palpating the brain could have other areas of application,
In one of many successful tests, the lab designed molecules to detect mutation sequences in historic biopsy samples preserved in wax from cancer patients.
and for treatment to be provided as soon after diagnosis as possible to provide optimal outcomes, with the potential to improve patientsquality of life in the long-term. t
Hope for new options for diagnosis and treatment The scientists hope that new treatment options will open up for epilepsy patients
genetics and disease diagnosis. But carrying out such analyses requires expensive lab equipment, making its application out of reach for many people who live in resource-limited places.
something that can be used immediately in cancer diagnosis. Professor Tim Maughan, Clinical Director of the Cancer Research UK/Medical Research Council Oxford Institute for Radiation Oncology, said:
#Tadpole endoscope offers new hope for gastrointestinal cancer detection Hong kong researchers have devised a swimming housing for a capsule endoscopy camera which can be steered around to provide better images inside the stomach
and endoscopy, where a similar system goes in the other end are so unpleasant and traumatic for the patient.
indeed, so-called capsule endoscopy currently the best way to get pictures of the intestines between the stomach and colorectal system, the boundary zone between gastroscopy and endoscopy.
so colleagues could be collaborating on a diagnosis using the app while unknowingly standing next to each other.
was tested for four weeks by 22 participants with a schizophrenia diagnosis. Schizophrenia is a long-term mental health condition
doctors will probably only be able to give it to patients with a firm diagnosis. In some parts of the world,
that kind of diagnosis isn possible. Still, the act of combining two different weapons antibodies and antibiotics to fight off infections is an intriguing idea.
but some hospital administrators have come to view them as the first must-have robot tech in a health care industry that's bracing for big changes with the imminent arrival of robot cleaners, diagnosticians, surgeons, and nurses."
and cells offer new solutions for cancer diagnosis and therapy. Understanding the interdependency of physiochemical properties of nanomedicines in correlation to their biological responses
and then a second antibiotic while they worked on a diagnosis. They soon learned his son's appendix had burst
The wide variety of faults found within lung cancers explains why targeted treatments have had limited success. Attacking a particular genetic mistake identified by a biopsy in lung cancer will only be effective against those parts of the tumour with that fault leaving other areas to thrive
and despite some positive steps being made against the disease it remains one of the biggest challenges in cancer research with fewer than 10 per cent surviving for at least five years after diagnosis. Building on this research will be a key priority for the recently established Cancer
The patient's diagnosis with Marjolin's ulcer an invasive and potentially deadly squamous cell cancer surprised physicians.
Some of these cells and molecules also were present in biopsy samples from the patient's ankle.
Their outstanding sensitivity simplifies the biopsy procedure. Minimally invasive techniques, also known as"keyhole surgery,"enable surgeons to operate on patients without requiring major incisions.
when performing lung, esophageal and joint biopsies, and most especially when operating inside the abdominal cavity. An endoscope is inserted through one or two small incisions in the abdominal wall
since the earliest days of endoscopy,"says Timo Cuntz, a member of the Project Group for Automation in Medicine and Biotechnology PAMB in Mannheim, a part of the Fraunhofer Institute for Manufacturing Engineering and Automation IPA.
which could result in fewer unnecessary prostate biopsies with less treatment-related morbidity, according to a new study in The Journal of Molecular Diagnostics.
High PSA levels are followed often by a biopsy to confirm the presence of cancer, and whether it's slow growing or aggressive."
"Moreover, only 25 percent of men with raised PSA levels that have a biopsy actually have prostate cancer.
One lncrna, PCA3, was commercialized recently as a urine test to identify which men suspected of having prostate cancer should undergo repeat prostate biopsy.
lncrna expression was compared in pooled prostate cancer tissue samples and matched normal tissues from 10 frozen biopsy specimens.
However, many patients will end up with a diagnosis of bacterial sinusitis and a prescription for antibiotics--despite evidence showing that in most cases,
Thus it is highly important to identify more sensitive and specific markers to improve early diagnosis as well as therapeutic strategies.
#New lab-on-a-chip could revolutionize early diagnosis of cancer Scientists have been laboring to detect cancer and a host of other diseases in people using promising new biomarkers called exosomes.
Zeng and his fellow researchers have developed the lab-on-a-chip for early detection of lung cancer--the number-one cancer killer in the U s. Today lung cancer is detected mostly with an invasive biopsy after tumors are larger than 3 centimeters in diameter and even
Diagnosis of lung cancer requires removing a piece of tissue from the lung for molecular examination.
Tumor biopsy is often impossible for early cancer diagnosis as the developing tumor is too small to see by the current imaging tools.
Our technique provides a general platform to detecting tumor-derived exosomes for cancer diagnosis he said.
and open up new perspectives for the diagnosis and specific treatment of eating disorders. Correcting the action of the protein mimicking the satiety hormonewe are presently working to develop a blood test based on detection of the bacterial protein Clpb.
With this discovery, scientists from the Helmholtz Zentrum München have identified a new biomarker for the diagnosis of the cancer cause.
-or right-handed form may have a multitude of practical applications, potentially leading to new and improved drugs, diagnosis methods, and pesticides.
The breakthrough could be important in developing effective molecules for use in a wide range of industries everything from the development of safer new drugs and disease diagnosis to less toxic pesticides.
In addition to the development of effective new drugs and diagnosis methods for diseases including cancer, it could potentially lead to new reenpesticides using pheromones tailored specifically to attract pollinators
The shock of the diagnosis continued to set in over the next few months as my wife, Laura,
The physician can then give a diagnosis without patients having to leave their homes. he stethoscope
and those that make taking muscle biopsies difficult. Interestingly there is no mention here of using these tiny bits of working muscle muscle that twitches in response to electricity
#Nanometer-Sized Robots Can Now Take Colon Biopsies Researchers have invented a noninvasive way for thousands of nanometer sized robots to perform tissue biopsies.
Eventually, the team will work on creating versions that can perform biopsies in the brain bloodstream, and even more locations throughout the body
Of course, a diagnosis is far from a cure, and a call to improve educational opportunities is far too facileho could argue with that?
That makes the report more like a jumble of facts than a diagnosis. Lennon says this is intentional.
Biopsies taken six to eight months after the procedure indicated that at least some muscle tissue grew in all five patients
"The conventional methods for diagnosis of Alzheimer's depend mostly on clinical symptoms or biopsy which is an invasive procedure.
"If it succeeds to become a practical solution for early diagnosis of Alzheimer's. Early identification can help in giving drug therapy to slow the degeneration process
Worse, almost half of them die within 12 months of diagnosis, because of the delay in seeking treatment.
Worse, almost half of them die within 12 months of diagnosis, because of the delay in seeking treatment.
will help improve the process of early stage prostate cancer diagnosis, researchers said. Glycoprotein molecules play an essential role in our immune response, because of
The findings show how the rate of false readings that come with antibody based diagnosis can be reduced by the new technology that focuses on the carbohydrate part of the molecule.
"Till that happens, early diagnosis and prompt treatment is the key
#Vaccine success holds hope for end to deadly scourge of Ebola The world is for the first time on the verge of being able to protect humans against Ebola,
and dramatically reduce diagnosis costs per patient compared to nonbatched or nonstandard tests. A traditional ELISA 96-well platewith the UCLA researcher new invention, the same steps are taken,
which is still the gold standard in the health care industry for making a definitive diagnosis. Also routinely used today is a newer method for rapidly identifying bacteria based on a DNA-analysis technique called quantitative polymerase chain reaction (qpcr),
"This means the present method can be utilized as a prescreening test for point-of-care bacterial diagnosis for various applications including medicine and food hygiene.""
Sadeghi Phd research on skin cancer prevention and analyzing dermoscopic images for early skin cancer diagnosis using intelligent computer technologies was recognized with a 2012 Innovation Challenge Award from the Natural sciences and Engineering Research Council
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