The engineered cells contain an antibody-like protein known as a chimeric antigen receptor (CAR) which is designed to bind to a protein called CD19 found on the surface of B cells including the cancerous B cells that characterize several types of leukemia.
A signaling domain built into the CAR promotes rapid multiplication of the hunter cells building an army of tumor-killing cells that tests reveal can grow to more than 10000 new cells for each single engineered cell patients receive.
Compartments within a cell are much like different parts of a car explains Vasanth Ramamurthy Phd first author of the study.
in order to power the car's engine proteins need to be in a specific compartment to properly exercise their functions.
It will help us make parts that are stronger lighter and function better for more energy-efficient transportation and energy production applications such as cars and wind turbines.
Seniors living in highly automobile dependent suburbs who lose their licenses can suffer a decreased quality of life as a result.
The new technology is designed for conventional lithium-ion batteries now used in billions of cellphones laptops and other electronic devices as well as a growing number of cars and airplanes.
which is on par with the time needed to pump petrol for current cars added Prof Chen.
#Miniature camera may lead to fewer accidents Measuring only a few cubic millimeters a new type of camera module might soon be integrated into future driver assistance systems to help car drivers facing
when facing a potential car accident: A brief moment of distraction, overtiredness or inattention--there are several reasons why the number of accidents in Germany is high, on the autobahns most of all.
"One can now think of using these films in automobile glass as an invisible deicer, and even in skyscrapers,"Tour said."
Every time the field flips, the polarity of the bars reverses, drawing the magnetized droplets in a new, predetermined direction, like slot cars on a track.
#Deriving Power Directly from Evaporation Eva, the first evaporation-powered car, rolls along, thanks to a moisture mill a turbine engine driven by water evaporating from wet paper strips lining its walls.
and a rotary engine that drives a miniature car. When evaporation energy is scaled up the researchers predict,
The researchers next built a small toy car, powering it with the Moisture Mill and were successful in getting the car to roll on its own,
powered only by evaporation. In the future, Sahin said, it may be possible to design engines that use the mechanical energy stored in spores to propel a full-sized vehicle.
or CAR, in blood-forming stem cells. Blood-forming stem cells are capable of turning into any type of blood cell,
and mutates too rapidly for T cells to fight against the virus. The researchers inserted a gene for a CAR into blood-forming stem cells in the lab. The CAR,
The CAR-modified blood stem cells were transplanted then into HIV-infected mice that had been engineered genetically with human immune systems.
The researchers found that the CAR-carrying blood stem cells successfully turned into functional T cells that could kill HIV-infected cells in the mice.
The findings strongly suggest that stem cell-based gene therapy with a CAR may be a feasible and effective treatment for chronic HIV infection in humans.
immunology and molecular genetics in the UCLA David Geffen School of medicine and a co-author of the study. ith the CAR approach,
Kitchen said the CAR approach is more flexible and potentially more effective because it could theoretically be employed in anyone.
and they know what car he drives, they can see where the car has been in recent days and months.
Investigators can map crime history both by location and time to reveal trends. And if a radiation alarm goes off,
Car thefts are down 17%.%Robberies are down 16%.%The Foothill area of Los angeles actually went an entire day without serious crime last year,
They are such powerful connectors of people that they are literally replacing their need and desire for cars.
As Steve Pendleton pointed out in a New Statesman piece about Britain reaching peak cars: But young people aren't simply swapping cars for buses or bikes;
they are choosing to own and use other technology instead, such as smartphones and tablet computers. It's not merely that the two trade off economically;
while travelling by bus, train or as a passenger in a car, only 10 per cent of them said they did so
while driving a car. Now think about where mass transit works best--where young people, retirees and even families are able to simply abolish their use of cars.
Especially in the U s. nowhere else but cities is this even possible. As young people turn away from cars--a phenomenon so powerful that it has had the marketing departments of car companies running scared for years--they are left with no other option than mass transit,
and that means increased density, urbanism, walkability and everything else required to bring our way of life in line with planetary boundaries.
Millennials aren't just fleeing the automobile; they're also explicitly fleeing Mcmansions and the suburbs.
literally represents a wealth transfer from the old economy--cars, oil, long commutes--to a new one built on a desire to capitalize on virtual connectivity by recapitulating it in the real world.
who are making decisions every day to buy an ipad instead of a new car, or to move closer to work
have a two-car garage and enslave yourself to lawn care? Who's aspiring to that t
especially big items like automobiles that are used only roughly 8 percent of the time. While it took Zipcar about six years to build up to 1, 000 cars in its network,
it the U k.-based Whipcar about six months to build up to the same number, she said.
That, in turn, causes people to think at least twice before a big-ticket purchase like a car that sits idle for 92 percent of the time.
they aren't just for big houses and cars anymore. Increasingly, Sarah Goodyear reports for The Atlantic cities, suburbs throughout the United states are investing in bicycle infrastructure.
and could be embedded in surfaces ranging from car dashboards to household floors to kitchen countertops.
and the inside surfaces of some new car models. Toyota announced in December that the 2013 Toyota Avalon Limited will be the first car to offer wireless charging with a Qi-powered console included under the dashboard.
Bas Fransen, chief marketing officer and head of business development for Convenientpower, a wireless power technology company,
car ownership costs rising (high gas prices, insurance, etc.;states making it difficult to get a driver's license;
and technology lessening the need for a car. So is this a trend we can expect to continue?
but in the future you may see it on your TV or in your car. I called Bayer Monday at his office in Green Island, NY.
Chief scientist and cofounder Gavin Mcintyre just won a half a million dollar proposal to adopt this same platform for automobile interior trim parts and cushions.
Towards that goal, we've driven our Street view cars throughout the Tohoku region again over the past months.
and are greater than those of all cars, trucks, planes, ships, and trains worldwide.""The program is in testing right now,
Some say that it new Wi-fi enabled busses that is luring people to leave cars behind
Finally, at the end of the rainbow, the Google self-driving car. The first step toward a robotic pancreas came in 1964,
Although several options to store hydrogen as a fuel for cars have been investigated, a practical and affordable way to store
and distribute hydrogen is still the biggest hurdle to the wide deployment of green, CO2 EMISSION-free cars.
because Baidu Maps will be able to integrate Uber This is similar to Google maps Uber integration after Google Ventures invested in the car-calling app.
With Airbnb flourishing, the whole market is on the verge of being opened up from sharing what in your closet (Threadflip, Rent the Runway) to your car (Flightcar, Lyft.
like type of car or estimated time of arrival) before they get in the car. The new fee will automatically be tacked on to that trip price up front
while tracking everything from road conditions to building health to cars to industrial equipment. The Internet of things is a term that being bandied about with increasing frequency these days.
And at CES last week Nvidia spent most of its keynote discussing how it uses deep learning to classify objects that a camera on a car may see in order to further its research in autonomous driving o
The next version of Applink its system for connecting smartphone apps to its SYNC infotainment system will allow third-party navigation apps to project their maps from the phone onto the built-in screens in its cars.
Earlier this month the Genivi Alliance also announced that it would offer open source middleware to support Android Auto integration into car infotainment products r
#Automatic Launches Its SDK, Turning The Car Into An App Platform Automatic, a startup whose sensor-and-software combo has been described as itbit for your car,
is today rolling out a software development kit and new hardware that turn your car into a platform for apps.
which has been updated to accommodate streaming real-time data from a car computer and sensors to apps running on your phone.
The apps draw relevant data from a car computer via the OBD port letting you do things like feed the exact mileage from a particular drive into Concur to expense a work trip
There are also apps for those looking to get peak performance from their cars, offering up stats on engine output
#Rentecarlo Launches U k. Peer-to-peer Car rental Marketplace Rentecarlo, the U k. startup and graduate of accelerator Ignite100, is officially launching today with a peer-to-peer car rental marketplace that lets anybody rent out their own car.
is that car owners can make money on their car inactivity while providing car renters with a more convenient option. here is a growing tendency in our society,
which is need the for on-demand services that allow for access rather than ownership, says Rentecarlo cofounder
and CEO Jacob Aleksander. e want to be at the intersection of car sharing, car ownership and car rental,
by giving access to a wide selection of cars rather than ownership and thereby making better use of cars.
At the same time, sharing your car can take 10 cars off the streets, which counteracts the increasingly crowded roads, traffic and pollution.
Anybody can apply to list their car for rental, although Rentecarlo vets all car renters listed on its platform.
The car owner then determines the rental price describes the car and uploads photos of the vehicle.
All bookings are made through the site, with the startup handling the required insurance and offering 24/7 road assistance cover in the event of a breakdown. ur insurance setup allows car owners to list their cars in less than a minute
and renters to instantly sign up, provide their information on our website and rent a car as soon as the car owner approves the request,
explains Aleksander. urthermore, we also allow citizens from all EU and Commonwealth countries to use the service for hiring cars when on vacation in the U k. or similar.
Of course car pooling in its many forms from taxi-style services like Uber to ridesharing are a plenty.
Rentecarlo cites easycar Club in the U k, . and Drivy and Gomore in Europe, as competitors with the closest business model.
There are also pay-as-you-go car clubs like Zipcar. And we shouldn forget traditional car hire companies, which Rentecarlo and similar startups in the U s,
. such as Getaround and Relayrides, are surely going up against. Not so fast, according to Ignite100 Paul Smith, citing a supply side problem in the car rental industry that sees 15 per cent of car rental requests go unfulfilled because of problems with supply
and offer their personal cars for hire, he says. To that end, Aleksander says weekly traffic
The startup launches with more than 1, 000 signups and almost 300 cars ready to be hired, the majority
For example, how many of Lamborghini 11 million Facebook fans could actually afford that car? While Facebook could make an educated guess,
#Google Straps Aclima Sensors To Street view Cars To Map Air pollution If a city knows what intersections are full of smog,
-and-a-half to attach air-quality sensors to its Street view cars. e designed our cities without data,
three Street view cars collected 150 million air quality data points over a month of driving around Denver, Colo.
Aclima-equipped Street view cars will crisscross the Bay Area and other cities this year as part of the next big data collection.
It could allow Google maps to route cars or pedestrians away from high-pollution areas to avoid exacerbating condensed pollution or breathing it in.
The ability to direct self-driving cars away from intersections where they might contribute to high-pollution zones could help convince cities theye a positive change.
The marketing funnel can be long especially for big purchases such as automobiles where people may do research for nine months before taking a test drive.
The Mexican telecommunications company Car-sa recently switched on the first of several links it plans to use to link up cellular towers
You can find them in cars airplanes robots and medical implants. But their use has been limited in aircraft
and Plug ships into electricity grid so they dont idle in port reducing emissions equivalent to 12000 cars per ship.
But this raises issues of safety should a hydrogen-fueled car be involved in a collision.
and in other low-visibility scenarios could help save at least some of the 32000 people who die in car accidents each year in the U s
Information from the infrared camera is processed by a computer that tries to identify relevant objects on the road such as cars, pedestrians or road signs.
#Radical New DNA Sequencer Finally Gets into Researchers Hands One day in 1989 biophysicist David Deamer pulled his car off California's Interstate 5 to hurriedly scribble down an idea.
but also heavy so they can t be used as structural materials where weight is critical##for example in the bodies of cars.
The company rounded up research subjects in the market for a car and then tracked the journey they took from researching to finally buying.
theye most likely ready to buy a car. hat a big deal, says the company senior executive for marketing,
In a demonstration at IBM Almaden research center, MIT Technology Review saw one recognize cars, people,
To recognize cars in video, for example, a programmer would work out the necessary settings on a simulated version of the chip,
for embedded chipshe type found in car dashboards and coffee makersy the end of the year (see enser, Faster Memory Challenges Both DRAM and Flash.
if tetrahedrite can be used to harness heat from car exhaust. Scullin says that other thermoelectric materials have achieved typically about 2. 5 percent efficiency in cars,
but tetrahedrite could reach 5 to 10 percent efficiency. hese aren incremental improvements, he says. heye really huge improvements that make really significant impact. l
providing a simple way to control access to your home, car, or office and perhaps dissuading would-be thieves.
The city of Brescia, in northern Italy, was facing a dramatic increase in the number of automobile accidents involving young drunk drivers.
for one thing, transform car-making. Parts made of these metals weigh far less than the steel parts ordinarily used in cars,
while being just as strong. The weight savings could reduce fuel consumption by 10 percent, according to an auto industry consortium.
the computer controlled the gas and brakes to pull to within 10 meters (roughly three car lengths) of the truck ahead.
Most automobile companies are working on full vehicle automation, but they need to overcome significant challenges before they can deploy those technologies (see riverless Cars Are Further Away Than You Think.
The technology demonstrated in Nevada in contrast, could be deployed today, since the system is automated only partially (the driver behind still steers, with the aid of a camera that shows the view ahead of the truck in front).
a feature in some cars that automatically keeps vehicles on the highway a safe distance from the ones around them.
The U s. Department of transportation has indicated that it plans to mandate such communications systems in new vehicles in the hopes of improving road safety (see he Internet of Cars Is Approaching a Crossroads.
it much harder for drivers of other cars to change lanes. would not advocate running very long sequences of these trucks close together,
and cars to the Internet, unleashing new streams of data about our everyday lives, one mobile ad company scents a new opportunity.
and cars with integrated data connections head to market. Those new data streams could form the basis for many new services and products,
It will launch a $149 device in June that plugs into a car diagnostic port
when a car airbags are deployed, or whether crash sensors on the bumpers have been triggered, potentially allowing ads pegged to incidents on the road. t could be had you just a little fender bender,
Lockhorn says of Kiip experiments in the car. The ad industry in general is interested in finding ways to use online-style ad tactics in the real world.
The way I drive my car is personal information. l
#Implant Lets Patients Regrow Lost Leg Muscle Five people who suffered serious leg injuries have been able to regrow muscle tissue in their legs thanks to a new regenerative medicine treatment.
RSS Manufacturing, a company in Costa Mesa, California, that produces custom automobile and plumbing components,
making it possible to create new applications in areas as diverse as factory optimization, car maintenance,
He been experimenting with Freeboard using a car data interface called Open XC. Prasad took data on the on-off state of windshield wipers to come up with a prototype of a warning alert that could someday be dispatched to a car a few kilometers back to warn the driver of wet roads. set it up
and did it in a matter of a few minutesnd I don code for a living,
First, Tesla sold 23,000 cars last year. The gigafactory, which would start production in 2017,
In the ideal scenario, that cost reduction would help Tesla produce a mass-market car similar in cost to the Nissan leaf or Chevrolet volt but that,
crucially, will be able to go more than twice as far on a charge (the car would also be able to accelerate faster than the Leaf).
If Tesla can sell as many cars as it hopes, there would likely be no alternative market for those batteries,
Some states are even reconsidering laws that restrict how Tesla can sell cars in their state,
a factory to supply 100,000 cars. anasonic can afford to lose the business, says Anderman.
it worth noting that 500,000 cars is still a tiny fraction of the worldwide auto industry.
GM sold nearly 10 million cars last year. If electric vehicles are ever to make a dent in the world auto market,
#Apps by the Dashboard Light Starting next month, many car buyers will be getting a novel feature:
Backseat passengers could get streaming movies and fast Wi-fi connections to smart watches and tablets in (and near) the car.
since it pulling data from the car, it locked down before it ever gets into the vehicle.
whose apps will be available in GM cars. Called Kaliki, BT Software app provides audio readings of storiesone by humans, not text-to-speech softwareulled from mainstream publications such as USA Today and TV Guide,
getting their apps included in a car could help them market versions that work on smartphones.
And apps in cars command much more attention if they are among just a few that a driver can choose from while sitting behind the wheel for an hour or two every day.
In the longer term, apps will emerge that draw on data generated by the car, says GM Ross.
Apps tapping information from many cars could alert drivers to accidents; signals indicating hard braking
or slipping wheels in other cars could warn of slick roads ahead. Sensors can ultimately help bring about semi-autonomous
or fully autonomous cars (see ata Show Google Robot Cars Are Smoother, Safer Drivers Than You or I. Henry Tirri,
CTO of Nokia, says the potential for apps in cars is given vast the amount of data vehicles produce. he car is already probably the densest sensor hub that an individual owns right now,
he says. See fter Microsoft Deal, What Left of Nokia Will Bet on Internet of things. In Audi case, the service will cost $100 for up to five gigabytes of data over six months,
GM has announced not pricing except to say that customers can get various plans combining service to their homes, phones, and cars.
Both GM and Audi are using AT&T to provide service (see M and AT&T Blur Line Between Car and Smartphone r
but also address a wide range of medical issues such as treatments for people involved in car accidents,
the miracle material that promises to transform everything from smartphones and computers to cars, buildings and satellites.
Rust-free cars Graphene repels water and is highly conductive. This combination delays the oxidising reaction that causes rust.
the miracle material that promises to transform everything from smartphones and computers to cars, buildings and satellites.
Rust-free cars Graphene repels water and is highly conductive. This combination delays the oxidising reaction that causes rust t
With regard to the virtual cockpit which was showcased in Q7 Audi said that the Q7 will be the first-of its-kind car that will continue to increase its knowledge;
Announcing its piloted driving system at the CES event Audi said that it is tantalizingly close to bringing its piloted car to the market.
Audi proved that a true turning point for the (autonomous) automobile has arrived d
#Britain's Transport Department has given go-ahead to test driverless cars on public roads According to a statement released by Britain's Department for Transport (Dft),
And what about mounting these scanners of Google street view cars? This scanning ability could be used to make maps far more interactive and realistic,
3d printed cars have been seeing significantly more attention ever since the crowdsourced automobile design and manufacturer Local Motors unveiled their Strati 3d printed car,
which is expected to be released later this year. But while the Strati-which can be built in a matter of hours-represents a monumental shift in modern manufacturing technologies,
materials and capital costs associated with building automobiles and other large complex structures is based San francisco Divergent Microfactories.
and democratize car manufacturing in the form of the company very first 3d printed supercar prototype,
Blade. ociety has made great strides in its awareness and adoption of cleaner and greener cars.
while these cars do now exist, the actual manufacturing of them is anything but environmentally friendly, says Czinger. t Divergent Microfactories,
wee found a way to make automobiles that holds the promise of radically reducing the resource use
It also holds the promise of making large-scale car manufacturing affordable for small teams of innovators.
Wee developed a sustainable path forward for the car industry that we believe will result in a renaissance in car manufacturing, with innovative,
eco-friendly cars like Blade being designed and built in microfactories around the world. hile the Strati is produced using fused deposition modeling (FDM) 3d printing,
a 3d-printed aluminum joint that connects pieces of carbon fiber tubing to make up the car chassis. Among other problems solved by the Node include cutting down on the amount of 3d printing required to build the chassis as well as the time to assemble the car components
Additionally, the reduction of materials and energy usage helps bring the weight of the car down as much as 90%compared to traditional cars,
"Nodes are the key building block we developed to build cars. They are made of a metal alloy
"The nodes, combined with carbon fiber tubes are the key components in building a car chassis. It took less than 30 minutes to assemble the chassis by hand.
the prototype is one of the greenest and most powerful cars in the world. As for power, the Blade is equipped with a 700-horsepower bi-fuel engine that can use both compressed natural gas or gasoline,
While the ability to create their own cars using their technology is one thing, Divergent Microfactories plans on releasing the platform into the hands of entrepreneurs
and small businesses around the world in an effort to help them set up their own microfactories to build their own cars and complex structures.
between the developments in self-driving cars as well as disruptions to car manufacturing itself, this is an exciting time for the near-future of transportation
#MASSIVIT 3d shows off GDP Gel Dispensing 3d printing technology by printing a Strati car Jun 26, 2015 By Alecgenerally speaking,
Envisioning a wide variety of applications, the Israeli developers have emphasized just its potential by 3d printing an entire car body in a single piece.
as the Israeli engineers emphasize by 3d printing the body of a car. As reported in Israeli media,
they 3d printed the body of a Strati car by Local Motors, with a bit of help from design specialists from Autodesk.
and the printed car is only one example of the opportunities that will be available in the near future.
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