#'Human touch'nanoparticle sensor could improve breast cancer detection (Phys. org) niversity of Nebraska-Lincoln scientists have developed a nanoparticle-based device that emulates human touch
In research funded with a grant from the National institutes of health, Saraf and Nguyen perfected a thin film made of nanoparticles and polymers
a tunneling barrier, a quantum dot, another tunneling barrier, and a drain electrode to suppress electron excitation
#Researcher's nanoparticle key to new malaria vaccine A self-assembling nanoparticle designed by a UCONN professor is the key component of a potent new malaria vaccine that is showing promise in early tests.
But a novel protein nanoparticle developed by Peter Burkhard, a professor in the Department of Molecular & Cell biology, in collaboration with David Lanar
The key to the vaccine's success lies in the nanoparticle's perfect icosahedral symmetry (think of the pattern on a soccer ball)
We are able to achieve our high density because of the design of the nanoparticle, which we control."
It took the researchers more than 10 years to finalize the precise assembly of the nanoparticle as the critical carrier of the vaccine
holds the patent on the self-assembling nanoparticle used in the malaria vaccine. Burkhard is also exploring other potential uses for the nanoparticle,
including a vaccine that will fight animal flu and one that will help people with nicotine addiction.
Guiding Brain tumor Resection Using Surface-Enhanced Raman Scattering Nanoparticles and a Hand-held Raman Scanner ACS Nano Article ASAPDOI:
Here we evaluated the ability of a hand-held Raman scanner guided by surface-enhanced Raman scattering (SERS) nanoparticles to identify the microscopic tumor extent in a genetically engineered RCAS/tv-a glioblastoma mouse model.
and correlation with histology showed that SERS nanoparticles accurately outlined the extent of the tumors.
because it uses inert gold#silica SERS nanoparticles and a hand-held Raman scanner that can guide brain tumor resection in the operating room o
#Color hologram uses plasmonic nanoparticles to store large amounts of information In the 4th century, the Romans built a special glass cup,
Similar to the Lycurgus cup, the new holograms can change colors due to light scattering off silver nanoparticles of specific sizes and shapes.
The new holograms consist of precisely engineered silver nanoparticles patterned over a substrate. A key difference in the new holograms is the smaller size of the diffraction fringes,
the fringes here are replaced with nanoparticles smaller than half the wavelength of light. The researchers showed that the narrower band diffraction,
For instance, two different types of plasmonic nanoparticles can be multiplexed, or combined but not coupled, at subwavelength distances.
By using nanoparticles of silver with different shapes and sizes, the researchers could control the colors.
In addition to providing multiple colors, multiplexing two nanoparticles has the advantage of increasing the bandwidth information limits.
The researchers showed that each nanoparticle carries independent information such as polarization and wavelength, which can be controlled simultaneously.
With twice the number of nanoparticles, the total amount of binary information stored can exceed the traditional limits of diffraction."
"It has been shown that nanoparticles with resonant properties can be uncoupled over subwavelength distances so their electromagnetic fields have minimal interaction,
"The device presented demonstrates that these nanoparticles can store and transfer independent information beyond the diffraction limits,
#Eco-friendly'prefab nanoparticles'could revolutionize nano manufacturing A team of materials chemists polymer scientists device physicists
and others at the University of Massachusetts Amherst today report a breakthrough technique for controlling molecular assembly of nanoparticles over multiple length scales that should allow faster cheaper more ecologically friendly manufacture of organic photovoltaics and other electronic devices.
It was Bag who put similar sized and charged nanoparticles together to form a building block then used an artist's airbrush to spray layers of electrical circuits atop each other to create a solar-powered device.
#Magnetic nanoparticles break the capacity barrier for antibody purification Monoclonal antibodies represent the largest and fastest-growing segment of international biopharma.
Now A*STAR researchers have developed a high-capacity method to purify monoclonal antibodies that uses magnetic nanoparticles and also introduces new operating conditions.
which causes the antibodies to be deposited on the surface of starch-coated magnetic nanoparticles (see image).
The high capacity of our nanoparticle method makes it much faster than column chromatography explains Gagnon.
In addition to solving the longstanding problem of productivity for monoclonal antibodies the nanoparticle approach can be applied to many other therapeutic proteins and also to viral vaccines.
Gagnon P. Toh P. & Lee J. High productivity purification of Immunoglobulin g monoclonal antibodies on starch-coated magnetic nanoparticles by steric exclusion of polyethylene glycol.
and composition of the nanorods means it is easier to control the properties of the bimetallic goldopper nanoparticles compared to nanoparticles made of just one metal,
Her team now plans to use the nanorods as seeds themselves to synthesize nanoparticles comprised of a goldopper core surrounded by a shell of another material, such as platinum, for energy applications
In order to view the behaviour of the cell membrane at the level of individual molecules the Cambridge team working with researchers from the University of Leeds squeezed them into a tiny gap between the mirrored gold facets of a nanoparticle sitting just above a flat gold surface.
The film can be applied onto degradable nanoparticles for injection into local sites or used to coat permanent devices such as orthopedic implants.
Yung-Eun Sung is both a group leader at the Center for Nanoparticle Research at Institute for Basic Science*(IBS) and a professor at the Seoul National University.
Group leader Yung-Eun Sung of the Center for Nanoparticle Research at IBS, says,"We expect that our synthetic approach will be developed to produce doped carbon materials based on other elements (e g.,
#Self-assembling nanoparticle could improve MRI scanning for cancer diagnosis Scientists have designed a new self-assembling nanoparticle that targets tumours,
The new nanoparticle, developed by researchers at Imperial College London, boosts the effectiveness of Magnetic resonance imaging (MRI) scanning by specifically seeking out receptors that are found in cancerous cells.
The nanoparticle is coated with a special protein, which looks for specific signals given off by tumours,
causing the nanoparticle to self-assemble into a much larger particle so that it is more visible on the scan.
used cancer cells and mouse models to compare the effects of the self-assembling nanoparticle in MRI scanning against commonly used imaging agents
and found that the nanoparticle produced a more powerful signal and created a clearer MRI image of the tumour.
The scientists say the nanoparticle increases the sensitivity of MRI scanning and will ultimately improve doctor's ability to detect cancerous cells at much earlier stages of development.
The newly designed nanoparticle provides a tool to improve the sensitivity of MRI scanning, and the scientists are now working to enhance its effectiveness.
so that the nanoparticle would light up with a luminescent probe once it had found its target,
"Before testing and injecting the nontoxic nanoparticle into mice, the scientists had to make sure that it would not become so big
They injected the nanoparticle into a saline solution inside a petri dish and monitored its growth over a four hour period.
The nanoparticle grew from 100 to 800 nanometres still small enough to not cause any harm.
The scientists are now improving the nanoparticle and hope to test their design in a human trial within the next three to five years.
"We're now looking at fine tuning the size of the final nanoparticle so that it is even smaller
"On a fundamental level, our work demonstrates electron-beam based manipulation of nanoparticles an order of magnitude larger than previously possible,
when they created the smallest-ever quantum dots single atom of silicon measuring less than one nanometre widesing a technique that will be awarded a U s. patent later this month.
Quantum dots Wolkow says, are vessels that confine electrons, much like pockets on a pool table. The dots can be spaced
the research team observed how single electrons jump in and out of the quantum dots, and devised a method of monitoring how many electrons fit in the pocket and measuring the dot's charge.
give scientists the ability to monitor the charge of quantum dots. They've also found a way to create quantum dots that function at room temperature,
meaning costly cryogenics is not necessary.""That's exciting because, suddenly, things that were thought of as exotic,
If these molecules are close to nanoparticles, the plasmons in the nanoparticles enhance the Raman signal coming from the molecules that have to be detected with several orders of magnitude.
The nanoantennas developed in this project only enhance the emitted Raman signal if the biomolecules are close to the hot spots Therefore,
'maskless'approach to producing nanoholes using silver nanoparticles. First, they deposited a nanometer-thin layer of silver onto a silicon wafer
The catalysts, tungsten-based bimetallic alloy nanoparticles of non-cubic symmetry, have high melting points and consequently are able to maintain their crystal structure during the chemical vapor deposition (CVD) process,
and the arrangement of the atoms in one of the planes of the nanocrystal catalyst facilitates the (n,
"Employing tungsten-based alloy nanocrystals with unique structure as catalysts paves a way for the ultimate chirality control in SWNT growth.
or emboss the raised numerals on credit cardsould process nanoparticles more subtly than the most advanced chemistry.
when applied to nanoparticle arrays, forms new nanostructures with tunable properties.""There is a great potential market for this technology,
platinum and other metallic nanoparticles Clem said the researchers are now starting to work with semiconductors.
A coating of nanoparticles that can build into another structure has a certain functionality we don't have right now.
For example, under pressure, the dimensions of ordered three-dimensional nanoparticle arrays shrink. By fabricating a structure in
the nanoparticle array will remain at a constant state, able to transmit light and electricity with specific characteristics.
At even higher pressures, nanoparticles are forced to sinter, or bond, forming new classes of chemically
composition and phase orientation of the initial nanoparticle arrays, a variety of nanostructures or nanocomposites and 3-D interconnected networks are achievable.
and Complexity have succeeded in developing a new technology that introduces metal nanoparticles on the surface of polymer nanocapsules made of cucurbit 6 uril.
and metal salts can serve as a versatile platform where equal sized metal nanoparticles can be distributed evenly on the surface of the polymer nanocapsules.
which can stabilize metal nanoparticles by preventing them from clustering together. The metal nanoparticle-decorated polymer nanocapsules exhibit the following properties in water:
high stability for up to 6 months; high dispersibility; excellent catalytic activity; and reusability in carbon-carbon and carbon-nitrogen bond-forming reactions with 100%conversion efficiency.
Even though metal nanoparticles are used variously in industrial, pharmaceutical and agricultural (fertilizer) applications as a catalyst, toxic liquids such as toluene and hexane are used usually as solvents in the carbon-carbon
However, this new technology is able to replace those toxic liquids as it allows carbon-carbon and carbon-nitrogen bond-formation with the use of metal nanoparticles as a catalyst
and reusability in water, which other existing metal nanoparticles on solid supports have not been able to do,
#Scientists develop a'nanosubmarine'that delivers complementary molecules inside cells With the continuing need for very small devices in therapeutic applications there is a growing demand for the development of nanoparticles that can transport
Recently researchers created nanoparticles that under the right conditions self-assemble trapping complementary guest molecules within their structure.
Although the transport of molecules inside cells with nanoparticles has been achieved previously using various methods researchers have developed nanoparticles capable of delivering
if the nanoparticles can actually travel through the bloodstream. That would be the dream but we have no evidence that they can actually do so Raymo says.
The size of these nanoparticles their dynamic character and the fact that the reactions take place under normal biological conditions (at ambient temperature
and neutral environment) makes these nanoparticles an ideal vehicle for the controlled activation of therapeutics directly inside the cells Raymo says.
Research and applications of iron oxide nanoparticles More information: Bacterial Nanometric Amorphous Fe-Based Oxide: A Potential Lithium-Ion Battery Anode Material.
#Nanoparticles could provide easier route for cell therapy UT Arlington physics researchers may have developed a way to use laser technology to deliver drug and gene therapy at the cellular level without damaging surrounding tissue.
the team paired crystalline magnetic carbon nanoparticles and continuous wave near-infrared laser beams for in
and Mohanty used a 50 to 100 milliwatt laser and the same carbon nanoparticle, which absorbs the beam,
continuous wave near-infrared laser and the nanoparticle to permeate the cell membrane without killing the cells.
whose lab created the study's crystalline magnetic carbon nanoparticle using an electric plasma discharge inside a toulene solution.
A significant advantage of the new method is that the near-infrared light absorption of the nanoparticle can be used to selectively amplify interaction of low power laser with targeted tissue
The magnetic properties of the nanoparticles also mean they can be localized with an external magnetic field;
"Carbon nanoparticles produced for the cancer study varied from five to 20 nanometers wide. A human hair is about 100,000 nanometers wide.
The magnetic carbon nanoparticles also are fluorescent. So, they can be used to enhance contrast of optical imaging of tumors along with that of MRI I
They observed the metal atoms becoming charged ions, clustering with up to thousands of others into metal nanoparticles,
#New approach may be key to quantum dot solar cells with real gains in efficiency (Phys. org) Los alamos researchers have demonstrated an almost fourfold boost of the carrier multiplication yield with nanoengineered quantum dots.
Quantum dots are novel nanostructures that can become the basis of the next generation of solar cells capable of squeezing additional electricity out of the extra energy of blue and ultraviolet photons.
but is enhanced appreciably in ultrasmall semiconductor particles also called quantum dots as was demonstrated first by LANL researchers in 2004 (Schaller & Klimov Phys.
In conventional quantum dots however carrier multiplication is not efficient enough to boost the power output of practical devices.
and cadmium selenide (Pbse and Cdse) can increase the carrier multiplication yield fourfold over simple Pbse quantum dots.
To realize the effect of slowed carrier cooling LANL researchers have fabricated Pbse quantum dots with an especially thick Cdse shell.
Qianglu Lin a CASP student working on the synthesis of these materials said A striking feature of the thick-shell Pbse/Cdse quantum dots is fairly bright visible emission from the shell observed simultaneously with the infrared emission from the core.
While the present CASP work is based on Pbse/Cdse quantum dots the concept of carrier-multiplication engineering through control of intraband cooling is general
#DNA-linked nanoparticles form switchable'thin films'on a liquid surface Scientists seeking ways to engineer the assembly of tiny particles measuring just billionths of a meter have achieved a new firsthe formation of a single
layer of nanoparticles on a liquid surface where the properties of the layer can be switched easily.
In addition, because the scientists used tiny synthetic strands of DNA to hold the nanoparticles together
the study also offers insight into the mechanism of interactions of nanoparticles and DNA molecules near a lipid membrane.
This understanding could inform the emerging use of nanoparticles as vehicles for delivering genes across cellular membranes."
"Our work reveals how DNA-coated nanoparticles interact and reorganize at a lipid interface, and how that process affects the properties of a"thin film"made of DNA-linked nanoparticles,
"said physicist Oleg Gang who led the study at the Center for Functional Nanomaterials (CFN) at the U s. Department of energy's Brookhaven National Laboratory.
the synthetic DNA strands used as"glue"to bind nanoparticles in this study have a natural tendency to pair up
Scientists at Brookhaven have made great use of the specificity of this attractive force to get nanoparticles coated with single synthetic DNA strands to pair up
"Many of the applications we envision for nanoparticles, such as optical coatings and photovoltaic and magnetic storage devices, require planar geometry,
Other groups of scientists have assembled such planes of nanoparticles, essentially floating them on a liquid surface,
"Using DNA linker molecules gives us a way to control the interactions between the nanoparticles."
a lipid, has a strong positive charge it attracts the negatively charged DNA strands that coat the nanoparticles.
That electrostatic attraction and the repulsion between the negatively charged DNA molecules surrounding adjacent nanoparticles overpower the attractive force between COMPLEMENTARY DNA bases.
and link the nanoparticles together more closely, first forming string-like arrays, and with more salt, a more solid yet elastic mesh-like layer."
As part of the study, the scientists examined the different configurations of the nanoparticles on top of the liquid layer using x-ray scattering at Brookhaven's National Synchrotron Light source (NSLS.
Because of the nanoscale size-regime, we might envision using such membranes for filtering proteins or other nanoparticles,
Understanding how synthetic DNA-coated nanoparticles interact with a lipid surface may also offer insight into how such particles coated with actual genes might interact with cell membraneshich are composed largely of lipidsnd with one another in a lipid environment."
"Other groups have considered using DNA-coated nanoparticles to detect genes within cells, or even for delivering genes to cells for gene therapy
I believe this approach has significant value as a platform for more detailed investigations of realistic systems important for these new biomedical applications of DNA NANOPARTICLE pairings,
#Technology using microwave heating may impact electronics manufacture Engineers at Oregon State university have shown successfully that a continuous flow reactor can produce high-quality nanoparticles by using microwave-assisted heating essentially the same forces
are essentially a"proof of concept"that a new type of nanoparticle production system should actually work at a commercial level."
"Nanoparticles are extraordinarily small particles at the forefront of advances in many biomedical, optical and electronic fields,
researchers worked with lead selenide nanoparticles, which are particularly good for the taggant technologies. Other materials can be synthesized using this reactor for different applications,
Shoei Electronic Materials, one of the collaborators, is pursuing"quantum dot"systems based on this approach, and recently opened new manufacturing facilities in Eugene, Ore.,
to use this synthetic approach for quantum dot enabled televisions, smartphones and other devices d
#Antimicrobial coatings with a long-term effect for surfaces Researchers at the INM Leibniz Institute for New Materials have produced now antimicrobial abrasion-resistant coatings with both silver
#New class of nanoparticle brings cheaper lighter solar cells outdoors Think those flat glassy solar panels on your neighbour's roof are the pinnacle of solar technology?
and tested a new class of solar-sensitive nanoparticle that outshines the current state of the art employing this new class of technology.
This new form of solid stable light-sensitive nanoparticles called colloidal quantum dots could lead to cheaper and more flexible solar cells as well as better gas sensors infrared lasers infrared light emitting diodes and more.
Collecting sunlight using these tiny colloidal quantum dots depends on two types of semiconductors: n-type which are rich in electrons;
and demonstrated a new colloidal quantum dot n-type material that does not bind oxygen when exposed to air.
But improved performance is just a start for this new quantum dot-based solar cell architecture. The powerful little dots could be mixed into inks
The field of colloidal quantum dot photovoltaics requires continued improvement in absolute performance or power conversion efficiency said Sargent.
Quantum dot photovoltaics set new record for efficiency in such devices More information: Air-stable n-type colloidal quantum dot solids DOI:
10.1038/nmat400 a
#Shatterproof screens that save smartphones University of Akron polymer scientists have developed a transparent electrode that could change the face of smartphones, literally,
As the team describes in their paper published in the journal Scientific Reports the new system is based on adding certain types of nanoparticles to materials as part of the manufacturing process that can be read later using a special device.
The idea revolves around several types of metal nanoparticles each of which has a unique melting point. Mixing the nanoparticles together allows for creating unique thermal signatures.
To use the nanoparticles manufacturers would simply add them into the mix when creating metals papers and even fluids.
The researchers say the addition of the nanoparticles doesn't change how a material looks doesn't react with anything in it
or impact how a finished product performs. Reading the new type of bar code requires a device capable of performing differential scanning calorimetry (DSC) a technique based on assessing the difference in the amount of heat required to heat different parts of a sample material.
For criminals to circumvent the process they would have to somehow find out which nanomaterials were added to a product to create its unique thermal signature then add the right mix of nanoparticles to their own counterfeit product to recreate it no easy feat.
The researchers claim their nanoparticle bar codes could be used with paper metals fluids and even drugs.
Taox-capped Pt nanoparticles as efficient catalysts for polymer electrolyte fuel cells More information: Covert thermal barcodes based on phase change nanoparticles Scientific Reports 4 Article number:
5170 DOI: 10.1038/srep05170abstractan unmet need is to develop covert barcodes that can be used to track-trace objects
This paper describes a new nanoparticle-based covert barcode system in which a selected panel of solid-to-liquid phase change nanoparticles with discrete and sharp melting peaks is added in a variety of objects such as
This method has high labeling capacity owing to the small sizes of nanoparticles sharp melting peaks
which organises metal nanoparticles into alternating layers in thin gel films to produce the sensors in a matter of seconds.
it is added then to a pink solution of gold nanoparticles. If any of the three genetic variations is present
Quantum dot photovoltaics set new record for efficiency in such devices Solar-cell technology has advanced rapidly as hundreds of groups around the world pursue more than two dozen approaches using different materials technologies
Now a team at MIT has set a new record for the most efficient quantum dot cells a type of solar cell that is seen as especially promising because of its inherently low cost versatility and light weight.
The new process is an extension of work by Bawendi the Lester Wolfe Professor of Chemistry to produce quantum dots with precisely controllable characteristics
Since the first progress toward the use of quantum dots to make solar cells Bawendi says The community in the last few years has started to understand better how these cells operate and
Buloviä#the Fariborz Maseeh Professor of Emerging Technology and associate dean for innovation in MIT's School of engineering explains that thin coatings of quantum dots allow them to do what they do as individuals to absorb light very well
The new work brings together developments from several fields to push the technology to unprecedented efficiency for a quantum dot based system:
The new work represents a turnaround for Bawendi who had spent much of his career working with quantum dots.
But his team's research since then has demonstrated clearly quantum dots'potential in solar cells he adds.
Arthur Nozik a research professor in chemistry at the University of Colorado who was involved not in this research says This result represents a significant advance for the applications of quantum dot films and the technology of low-temperature solution-processed quantum dot photovoltaic cells.#
#There is still a long way to go before quantum dot solar cells are commercially viable but this latest development is a nice step toward this ultimate goal.
Received 06 december 2013 Accepted 15 april 2014 Published online 25 may 2014energy Level Modification in Lead Sulfide Quantum dot Thin Films Through Ligand Exchange.
#Nanoparticles on track to distinguish tumour tissue Gold nanoparticles could be used to help detect the margins between tumours and normal tissue,
whether the nanoparticles would work as effective optical contrast agents to provide an estimate of the size and shape of tumour margins during surgery.
"Most research has been done with straight gold nanoparticles as contrast agents but the problem with them is they absorb light very strongly.
"Silica-gold nanoparticles provide greater contrast, visibility To get around this, Mr Duczynski used silica nanoparticles coated with a gold shell (silica-gold core-shell nanoparticles) in his research."
"There are some theoretical and experimental papers where it was observed that by varying the dimensions of either the silica core
"Ultraviolet spectroscopy was used on the silica-gold core-shell nanoparticles made by Mr Duczynski to better understand their optical properties, such as extinction, scattering and absorption.
The research also involved the development of iron oxide-gold core shell nanoparticles.""This particle system was attempted because
"I was able to see some scattering of the iron oxide-gold core-shell nanoparticles,
Recently biomedical researchers have found ways to increase the effectiveness of certain contrast agents by associating them with nanoparticles.
Researchers are now exploring the multipurpose use of nanoparticles. If particles could be loaded with several types of contrast agents
though compounds packaged together into a nanoparticle cannot always play well together. For example contrast agents may bind to other chemicals reducing their effectiveness.
In addition when contrast agents are enclosed inside a nanoparticle they may not work as well. Attempts to attach agents to the outer surface of nanoparticles via covalent formation are also problematic as they can negatively affect the activity of the nanoparticles or the compounds that they carry.
Kong Smith and colleagues tackled these challenges by using interactions between naturally occurring biomolecules as a guide.
The group hypothesized that the same types of forces could be used to attach a contrast agent to the surface of a type of nanoparticle called a liposome
Gadolinium stably associated with the modified nanoparticles in solution and experiments in animal models showed that these nanoparticles produced clear diagnostic images.
The strategy works like Velcro on a molecular level to adhere functional units to the outer leaflet of a liposome said Smith who was first author on the study.
10.1021/la500412r) Kong and Smith developed a process for chemically cross-linking the components of the nanoparticle that prolonged the life of the nanoparticles in biological conditions.
Nanoparticle pinpoints blood vessel plaque e
Overtext Web Module V3.0 Alpha
Copyright Semantic-Knowledge, 1994-2011