If a hospital discharged a patient and he or she ended up being readmitted within 30 days for the same issue,
the hospital would be penalized. And doctors, hospitals and other healthcare providers were encouraged to form networks Accountable Care Organizations (ACOS) to coordinate care
and align their economics around improved care and outcomes. The good news: economics are aligned around improving patient care and outcomes.
a problem remains once a patient leaves the doctor s office, it becomes difficult to see what s going on with his or her health.
which could land the patient back in the hospital or (at a minimum) back at the doctor s office.
Mobile in (medical practice When it comes to healthcare, mobile enables interactions and insights that were previously unimaginable,
if their doctor recommended they do so, they would use their smartphones to track their health and fitness even more.
prior to the legalization of medical and recreational marijuana use. The number of murders, sexual assaults, violent robberies and other assaults fell by 5. 6 percent.
#Sanaria will use robots to mass produce a promising new malaria vaccine Sporobot would increase the speed of production 20 30 times over.
What if you had developed a vaccine for malaria that, in early trials, was 100%effective.
But you couldn t get the funding you needed to produce enough of the vaccine to market it because of political wrangling over the budget.
First, design a robot to help produce the vaccine, and, second, run a crowdfunding campaign to pay for it.
That s exactly what#Sanaria, a biotechnology founded in 2003 by long-time malaria researcher Stephen Hoffman and based in a suburb of Washington,
#Malaria#infects about 200 million people every year and kills 600,000 of them.##Vaccines have been notoriously ineffective against the disease,
which stems from a parasitical infection. Last year, Sanaria reported that in a Phase I clinical trial
whose participants were consenting U s. veterans, the vaccine administered at the higher of two doses kept all the patients who got it from becoming infected with malaria
when bitten by mosquitos carrying#Plasmodium falciparum, #which causes 98 percent of all malaria deaths.
This year, the company will conduct trials in the U s.,Mali, Tanzania, Equatorial guinea and Germany.
To produce the vaccine, called Pfspz, Sanaria cultivates mosquitos in a sterile environment and infects them with#Plasmodium falciparum (the Pf in Pfspz).
filter out other contaminants and gather them up into an injectable vaccine. If it sounds laborious,
which is nowhere near enough to mass-produce a global vaccine. So two years ago, Sanaria began working with theharvard Biorobotics Lab#to develop a robot that could do the work faster.
The work has to be done under sterile conditions to produce a vaccine that could earn FDA approval.
That makes more vaccine available at a lower cost which is important for a disease that disproportionately affects developing countries.
What s left is to assemble the various functions into a single desktop robot, Tenzer told Singularity Hub.
It s easy to think that medical robots were#last year s innovation. But while they re#not a new idea#doesn t mean that all
If robotics manage to subdue malaria where other modern medical technologies have failed so far, it will be a powerful sign of how much the technology might accomplish as it matures.
Malinow, who holds the Shiley Endowed Chair in Alzheimer s disease Research in Honor of Dr. Leon Thal,
noted that the beta amyloid peptide that accumulates in the brains of people with Alzheimer s disease weakens synaptic connections in much the same way that low-frequency stimulation erased memories in the rats.
#Researchers discover new treatment for diabetes Researchers discovered a small molecule that inhibits an enzyme that degrades insulin.
and treat diabetes after decades of searching. They have discovered a whole different method for maintaining insulin in the blood:
and helps regulate the body response to sugars process that goes awry in type 2 diabetes.
Genetic studies have shown that people with type 2 diabetes are more likely to have mutations in the gene that encodes a protein called insulin-degrading enzyme, or IDE.
Patients with type 2 diabetes either have an insufficient amount of insulin in their blood
Researchers have speculated for decades that a drug that could inhibit IDE might help some type 2 diabetes patients.
which make up the majority of medicines, are compounds far smaller than less common biological medicines like antibodies.
They are developed using libraries of thousands or millions of known chemical substances. Each compound is screened to see
such as an enzyme or other protein known to be involved in a disease. Pharmaceutical companies may use robotics to test many chemical reactions in parallel.
The newly identified IDE inhibitor could be the starting point for developing a powerful new drug for type 2 diabetes.
just as mass, anonymised patient records could improve health care. But its success depends on service providers persuading users (farmers
#The Living Heart Project will use 3d simulation of the human heart to combat heart disease The World health organization recent research has revealed that 17.3 million people died from cardiovascular diseases worldwide in 2008,
A report by the American Heart Association, Forecasting the Future of Cardiovascular disease in the United states, believes the total direct medical costs of cardiovascular disease will reach $818. 1 billion over the next three decades.
and prevent disease. Normally, this is done by physically analyzing the anatomy of a human being, but a groundbreaking idea could change the face of medicine for good. 3d software design companies Dassault systèmes
and 3dexperience have joined forces on a new venture theye named The Living Heart Project to try
and combat he biggest challenge in the medical science right nowcardiovascular disease. The project started by partnering with some of the best brain
The project is breaking new ground in the study of heart disease and personalized treatment, since researchers are limited currently at being able to predict a pacemaker effect on a patient before surgery, for example.
These 3d designs could become the norm for diagnosing and treating heart conditions in hospitals all over the world,
where doctors could simulate how a patient might respond to different types of treatment, reducing the risks
and potential failures of medications and procedures used today. Instead of looking at pages of a patient medical history,
Dr. James C. Perry, Professor of Pediatrics at University of California San diego and Director of Electrophysiology and Adult CHD at Rady Children Hospital in San diego explains,
#25%of patients now read online physician reviews There has always been a love/hate relationship between doctors and the Internet.
Some doctors bristle at the fact that many patients now shop for physicians in the same way they shop for restaurants and plumbers:
A recent study by researchers at the University of Michigan says 25 percent of Americans now look online for doctor reviews before making an appointment.
which was published in the Journal of the American Medical Association, says a third of those people make a decision to see
or not see a particular doctor based on reviews they read. There are now 40 to 50 doctor-review sites for patients to choose from,
the biggest among them being Healthgrades, Ratemds and Vitals. Also, general review sites such as Yelp also offer ratings for medical practices and specific physicians.
It gets better. The study shows that the doctors are nervously reading the reviews too, and even changing parts of their bedside manner to avoid bad ratings.
Some doctors bristle at the idea of being reviewed Yelp-style. After all, medicine is a business where customer service is important,
but it also a science. Doctors are often talkative during the ubjectivepart of an exam,
when patients are asked to describe their symptoms, but less conversant during the bjectivepart, when they get down to the job of examining the patient in a scientific way.
Also, new technology in doctors offices may not help matters. With the new focus on real-time documentation of care in electronic health records
doctors can sometimes be preoccupied with their handheld computers. Patients can feel ignored. And doctors sometimes simply must give patients bad news. Some doctors believe bad news in the exam room can cause bad feelings that turn into bad reviews on sites like Healthgrades. com
. But the review sites are on the minds of doctors. Both the Congress of OBGYNS and the American Psychiatric Association have held panel discussions about online reviews at recent meetings
#Longevity gene may enhance brain power For the first time ever, scientists have shown that people who have a variant of a gene called KLOTHO also have improved cognitive abilities,
including better memories and enhanced thinking skills. In parallel research on mice, the researchers found that
when they increased the levels of the gene variant, the mice got smarter, perhaps due to increased connections between nerve cells.
This could provide a promising avenue of research for tackling Alzheimer disease. The study lead author, Dena Dubal said:
his could be a major step toward helping millions around the world who are suffering from Alzheimer disease and other dementias.
we may be able to counter dementias. In the human arm of the research, the scientists gave a whole battery of cognitive tests to over 700 people with and without the gene variant.
sex or genetic risk factors for Alzheimer disease. Another of the study authors, Roderick Corriveau, said:
Although preliminary, they suggest that a form of klotho could be used to enhance cognition for people suffering from dementia.
Glass has seen its strongest professional reception in medicine, with a variety of pilot programs in hospitals, operating rooms,
and other parts of medical life. t way too early to tellif Glass will become standard in medical schools,
ut a lot of people in medical education are interested. She heads up Medtech Boston a nonprofit organization that has been conducting projects
and competitions involving medical uses of Glass. Joe noted a surprising fact: Medical schools in the U s. are generally slow to adopt new technologies,
and was used for collecting data as well as video t would dramatically change medical education. Imagine an attending physician seeing what you saw during a simulation,
In August, another 20 to 30 pairs will go to first-and second-year students, for use in anatomy labs, the medical simulation center, the ultrasound institute,
where patient-physician encounters about specific diseases will be transmitted in real time over 16 miles between the medical center and a lecture hall.
And an unusual point-of-view will be added to Glassgrowing medical repertoire: the patient. hat one of the uses I most excited about,
assistant clinical professor of emergency medicine at the UCI medical school and head of the Glass program there.
ike whether the student is facing the patient, unconscious eye rolls from the student doctor, head rolls.
search-and-rescue and in the medical domain, we can take the idea of in-theater robots completely off the table,
Power Japan Plus intends to first launch batteries for the medical device and satellite industries, which are focused hyper on safety.
Sensors help agriculture by enabling real-time traceability and diagnosis of crop, livestock and farm machine states.
The use of animal testing for medical research than for cosmetics testing is much easier to defend.
Even as medical researchers produce rgans on a chipto help with drug testing, developing human skin for cosmetics testing has remained elusive.
Researchers at King College London and the San francisco Veteran Affairs Medical center report they have cleared those hurdles. ur new method can be used to grow much greater quantities of lab-grown human epidermal equivalents,
Making the skin from stem cells means that particular diseases could be produced intentionally for study,
including common skin ailments like dermatitis in which a defective skin barrier means that toxins cannot be repelled handily
Admittedly, these diseases are neither life-threatening nor medically exciting, but they are a big nuisance for those who suffer from them.
how the barrier is impaired in different diseases and how we can stimulate its repair and recovery,
both to study disease behavior and to test drugs, is a rapidly growing market. In many cases its benefits are so hypothetical eliminating negative outcomes that would,
Consumer Physics has developed three different applications for identifying food, medicines, and plants. During a short demo,
The technique could help scientists develop treatments for patients with some brain diseases as it could allow problematic parts of the brain to be switched off
#Mayo Clinic s Better turns your smartphone into a personal health concierge The Mayo Clinic is offering unlimited access to the famed hospital nurses through a smartphone app for about $50 a month.
The Mayo Clinic partnered with Better, a California-based health technology startup, to launch the new subscription-based app.
The app is covered not by insurance but offers real-time, 24/7 health care assistance. Think of it as a mobile Webmd.
Along with real-time video chats with Mayo Clinic nurses, the new service also includes personally-tailored health information culled from Mayo Clinic databases
said Paul Limburg of Mayo Clinic Global Business Solutions in a press release. eople consistently tell us they want more convenient access to Mayo Clinic knowledge.
and invested in Better to create a powerful way for people to connect with Mayo Clinic in their homes and communities,
Concierge medicine could also be a potential new revenue stream for the Mayo Clinic. Fast Company has covered previously New york-based medical concierge service Sherpaa and Oscar, a new health insurer which tailors its products for web and mobile use.
Because apps and subscription services are largely outside of the scope of FDA regulations, they are a potential moneymaker for health-minded businesses and entrepreneurs,
Better founder Geoffrey Clapp was previously an executive at telemedicine pioneerhealth Hero Network; his new company was launched with $5 million from venture capital fund The Social+Capital Partnership and the Mayo Clinic itself.
The Mayo Clinic Global Business Solutions wing has been actively building partnerships with everything from benefits providers to a variety of software developers.
The Mayo Clinic is entering a crowded market of smartphone-based concierge medicine firms. Beyond Sherpaa, there also Grand Rounds, Stat Doctors, Doctor on Demand,
and even a free app for Canadians, Medeo, which offers subsidized concierge medicine services via smartphones for residents of British columbia.
For Better, the Mayo Clinic, and other concierge medicine providers, the real (and unanswered) question is just how much of a market for their services really exists via smartphone apps s
#3d printed Osteoid cast with built-in ultrasound helps bones heal faster Osteoid cast Old-fashioned casts for broken bones can smell
and cause itching. But 3d printed casts can take care of those issues. Deniz Karasahin has designed the next step:
a custom cast with an ultrasound device to speed up bone healing. Karasahin Osteoid is, obviously, just a design concept,
The therapy has been tricky to administer, because it requires placing ultrasound leads on the skin directly over the bone injury.
That impossible with an old-school plaster castut not with a 3d printed cast of the future.
could provide a new drug target for the treatment of the disease that affects more than five million Americans,
but until now, p25 role in Alzheimer pathology was understood not well. his protein appears to help maintain normal brain activity,
Elevated p25 levels in the brain have been documented upon exposure to neurotoxic stimuli such as oxidative stress and beta amyloids. n this study
whether the blockade of p25 generation could mitigate pathological phenotypes in the Alzheimer brain, Tsai says.
In the mouse model of Alzheimer disease, inhibiting p25 production improved cognitive function, greatly reduced plaque formation and neuroinflammation, hallmark features of Alzheimer disease.
These results hold out the hope that a drug that regulates p25 could benefit Alzheimer disease patients by improving cognitive function
and perhaps delaying the development of brain pathology, Tsai says. This work was supported in part by the National institutes of health and the Howard Hughes Medical Institute M
or treat diseases with unprecedented sophistication, says Daniel Levner, a bioengineer at the Wyss Institute at Harvard university.
and control of the nanobots is equivalent to a computer system. his is the first time that biological therapy has been able to match how a computer processor works,
An obvious benefit of this technology would be cancer treatments, because these must be cell-specific and current treatments are targeted not well.
you don have to be clinically paranoid to find something worrying in the prospect of a highly automated warship that can be controlled by anyone who has the right login information.
When Hall first saw the wireless bulb, she immediately thought of medical technology seeing that devices transplanted beneath the skin could be charged non-intrusively.
Witricity is now working with a medical company to recharge a left-ventricular assist device heart-pump essentially.
or deliver food and medical supplies to disaster areas. As the science advances, it becoming increasingly possible to dispatch robots into war zones alongside or instead of human soldiers.
Some issues are the same ones that plague the adoption of any radically new technology:
#Researchers discover marijuana s anxiety relief effects Researchers at Vanderbilt University have found cannabinoid receptors, through
in a key emotional hub in the brain involved in regulating anxiety and the flight-or-fight response.
The discovery may help explain why marijuana users say they take the drug mainly to reduce anxiety,
said Sachin Patel, M d.,Ph d.,the paper senior author and professor of Psychiatry and of Molecular Physiology and Biophysics.
he natural endocannabinoid system regulates anxiety and the response to stress by dampening excitatory signals that involve the neurotransmitter glutamate. hronic stress or acute,
severe emotional trauma can cause a reduction in both the production of endocannabinoids and the responsiveness of the receptors.
Without their ufferingeffect, anxiety goes up. hile marijuana xogenouscannabinoids also can reduce anxiety, chronic use of the drug down-regulates the receptors, paradoxically increasing anxiety.
This can trigger vicious cycleof increasing marijuana use that in some cases leads to addiction.
In the current study, the researchers used high-affinity antibodies to abelthe cannabinoid receptors so they could be seen using various microscopy techniques
Patel said. ow can we see how that system is affected by stress and chronic (marijuana) use?
and strengthen muscles in aged mice People become less able to bounce back from injuries as they age.
This is a problem that adds risk to many of the common medical procedures the elderly face.
healthy tissue to recover from illness or injury. But because stem cell therapies remain cutting edge,
they have largely been used to target life-threatening problems such as heart failure. Stanford Helen Blau, director of the Baxter Laboratory for Stem Cell biology, studies a more banal
but also more ubiquitous, use of stem cells in the body: helping muscles repair themselves. The lab most recent findings suggest that stem cell therapy could be used to help older patients recover from muscular injuries, for example from falls,
or perhaps even weakness following surgery. At a biological level, the stem cells that repair muscle damage lose their ability with age to generate new muscle fibers.
But the older stem cells can be spurred to function like younger cells. Studying stem cells from elderly mice,
a post-doc in Blau lab who is a co-author of the recent study published in Nature Medicine.
The same basic process could lay the groundwork for helping human patients heal after surgery
or an injury. his really opens a whole new avenue to enhance the repair of specific muscles in the elderly, especially after an injury.
Our data pave the way for such a stem cell therapy, Blau said. Other recent work in stem cell therapy has looked similarly for ways the cells could improve functioning of existing organs, rather than building replacements through regenerative medicine.
For instance one recent study suggested that the cells may be able to kick-start insulin-making in pancreas in Type-1 diabetics by replacing Beta cells.
These approaches may lack the heroics of organs grown in the lab, but theye likely to reach the clinic long before replacement organs are available s
#Bitcoin is not only digital currency, it s Napster for finance Bitcoin will start its transformation from a mere currency into an entire open-source.
#High-tech glasses help surgeons see cancer The glasses are designed to make it easy for surgeons to differentiate cancerous cells from healthy cells.
Researchers at the Washington University School of medicine have developed high-tech eyewear that helps surgeons detect cancer cells, which glow blue
The special glasses are designed to make it easy for surgeons to differentiate cancerous cells from healthy cells allowing surgeons to make sure no cancer cells are left during surgery.
Phd, a professor of radiology and biomedical engineering at the university. The technology involve a head-mounted display, custom video technology,
The usual procedure for surgery requires doctors to remove tumors and neighboring tissue which may or may not have cancer cells.
a second surgery is recommended usually to remove additional tissue that is also tested for the presence of cancer.
The special eyewear can potentially eliminate the need for follow-up surgical procedures and save patients from more stress and anxiety
but it has already been used during surgery at the Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of medicine.
Julie Margenthaler, MD, an associate professor of surgery at Washington University and one of the breast surgeons who has performed surgery with the special eyewear,
if these glasses eliminated the need for follow-up surgery and the associated pain, inconvenience and anxiety.
Dr. Achilefu, who also happens to be co-leader of the Oncologic Imaging Program at Siteman Cancer Center,
is seeking approval from the FDA for a different molecular agent that he is helping to develop for use with the special eyewear.
The title of the patent, hermotherapy Apparatus for the Treatment and Preventions of Cancer in Male and Female Patients and Cosmetic Ablation of Tissueand is focused a heat apparatus for the treatment and prevention of cancer tissues, specifically breast cancers.
and Preventions of Cancer in Male and Female Patients and Cosmetic Ablation of Tissueand is focused a heat apparatus for,
but also the prevention of cancer tissues and, more specifically, breast cancers. Another embodiment of this patent is for the use of the apparatus for the minimal and noninvasive cosmetic applications specifically to destroy
pparatus and Method for Preconditioning/Fixation and Treatment of Disease with Heat Activation/Release with Thermoactivated Drugs and Gene Productsauthored by John Mon, COO for Medifocus.
and Method for Preconditioning/Fixation and Treatment of Disease with Heat Activation/Release with Thermoactivated Drugs and Gene Products.
in our opinion, is the future of medicine. f
#Dealing with Drought: Reaping the Benefits of Cover crops (Op-Ed) Margaret Mellon is a senior scientist for food and the environment at the Union of Concerned Scientists (UCS.
and into medical sutures scaffolds and protective burn coverings that dissolve over time Making Shrilk required carefully analyzing the chemistry of insect chitin.
The U s. Food and Drug Administration has approved already Shrilk's ingredients which would make it easier to use for medical purposes.
Medical applications So what are some uses for software that can identify human emotions based on facial expressions?
Facet's applications are incredibly far-reaching from treating children with autism to play-testing video games.
Recognizing other people's emotions based on their facial expressions is a challenge for many people who have an autism spectrum disorder particularly children.
As a research professor at the University of California San diego's Machine Perception Lab Bartlett has been studying the use of facial recognition software to help people with autism for several years. 5 Controversial Mental health Treatments
This game helps children with autism recognize other people's emotions through their facial expressions as well as teaches them how to make facial expressions that express their own feelings.
but with Facet doctors could make more accurate depression diagnoses and also determine whether their patients are responding well to their medication Bartlett said.
with up to 10 hospitals cleared to participate. The company is currently studying the device for treating Hepatitis C with patients on chronic dialysis,
and the Ebola study is based on its protocol l
#Medgadget@CES 2015: ADAMM Intelligent Asthma Management Wearable Walking through expansive, smoke-filled casinos, traversing the miles and miles of exhibitors,
and wading through the crowds too close for comfort, this editor was afraid his asthma might flare up as he made his way around CES in Las vegas last week.
Perhaps if he were wearing a smart sensing patch called ADAMM, asthma would be the least of his worries.
ADAMM (Automated Device for Asthma Monitoring and Management) is an upcoming wearable developed by Rochester, NY based Health care Originals.
Measuring about the diameter of a hockey puck, this smart patch can not only tell when the wearer is experiencing an asthma attack by measuring heart rate,
he explained that pediatrics is a huge opportunity for the company. Children aren always able to perceive
if their asthma is starting to flare up, and even then, they often lack the discipline to use their inhaler.
ADAMM can help ensure that parents can monitor for asthma flare-ups, even when they are away from their kids.
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