a research team led by investigators at Beth Israel Deaconess Medical center (BIDMC) has uncovered previously unknown steps in the development of insulin resistance, a hallmark of type 2 diabetes.
#DNA nanoswitches reveal how life's molecules connect Now a new approach developed by researchers at the Wyss Institute for Biologically Inspired Engineering Boston Children's Hospital
Professor of Vascular Biology at Boston Children's Hospital and Harvard Medical school and a Professor of Bioengineering at Harvard SEAS.
Lee Smith MD chief of pediatric otolaryngology at Cohen Children's Medical center and David Zeltsman MD chief of thoracic surgery at Long island Jewish Medical center both part of
"said co-author Joseph E. Bavaria, MD, from the Hospital of the University of Pennsylvania in Philadelphia."
Results of a Mayo Clinic study comparing the new model to the current standard, the Breast cancer Risk Assessment Tool (BCRAT), are published in the Journal of Clinical Oncology."
for the presence of a breast cancer,"says Amy Degnim, M d.,a surgeon at Mayo Clinic and a senior author of the study."
Dr. Degnim and her colleagues studied a cohort of approximately 10,000 women who had benign breast biopsies at Mayo Clinic
and 734 matched controls sampled from the Mayo Clinic BBD cohort. They validated the model using an independent set of women from the Mayo BBD cohort (378 patients with a later breast cancer
About half of all screening-aged women have dense breast tissue according to Deborah Rhodes M d. a Mayo Clinic Breast Clinic physician
The study conducted at Mayo Clinic included 1585 women with heterogeneously or extremely dense breasts who underwent an MBI exam at the time of their screening mammogram.
so our finding of an additional 8. 8 cancers per 1000 women makes MBI a very compelling option for women who elect supplemental screening says Dr. Rhodes. Michael O'connor Ph d. a Mayo Clinic scientist
because it incorporates many of the advances in MBI pioneered here at Mayo Clinic and shows that studies can be performed safely with low radiation exposure to the patient says Dr. O'connor. This means MBI is safe and effective as a supplemental screening tool.
what MBI can offer women with dense breasts says Amy Conners M d. chair of Mayo Clinic's Breast Imaging Division
of which have recorded astonishingly positive results in the clinic and are able to prolong the lives of seriously sick patients.
Joining forces with dermatologists and oncologists from the University Hospital in Zurich and backed by the University Research Priority Program"Translational Cancer Research,
Empa and the University Hospital Zurich thus teamed up to develop the sensor"Glucolight,""which gages the blood sugar level through the skin,
and the first clinical studies are scheduled at the University Hospital Zurich for 2015. However it could be years before the use of Glucolight becomes standard.
Empa and the University Hospital Zurich are currently in negotiations with partners for the industrial production of the sensor.
and possibly the overall aging process. said Audrey Tyrka MD Phd Director of the Laboratory for Clinical and Translational Neuroscience at Butler Hospital and Associate professor of Psychiatry and Human Behavior at Brown University.
assistant professor of regenerative medicine at Wake Forest Baptist Medical center and a co-inventor of the system. ut how do they know when theye removed enough tissue?
in addition to the inventors, were James M. Provenzale, M d.,Duke university Medical center and Emory University; and Corey F. Saba, D. V. M.,Karen K. Cornell, D. V. M.,Ph d,
Wake Forest Baptist Medical center (www. wakehealth. edu) is recognized a nationally academic medical center in Winston-salem, N c,
. with an integrated enterprise including educational and research facilities, hospitals, clinics, diagnostic centers and other primary and specialty care facilities serving 24 counties in northwest North carolina and southwest
when they actually perform these procedures in a clinic, "said rising junior Miguel Sobral, a team member from Lisbon, Portugal.
"says the researcher from the University of Bonn Hospital. Simplified test to test novel viruses for risk of human infection Triggered by epidemics such as SARS and Ebola,
in association with Montpellier Regional University Hospital and Stanford university, have transformed bacteria into"secret agents"that can give warning of a disease based solely on the presence of characteristic molecules in the urine or blood.
and require sophisticated technologies that are often available only in hospitals. This is where biological systems come into play.
in association with Professor Eric Renard (Montpellier Regional University Hospital) and Drew Endy (Stanford university), applied this new technology to the detection of disease signals in clinical samples.
Multiple hospitals have agreed to provide blood samples for analysis to Wistar for this next study."
Stephen Elledge, an HHMI investigator at Brigham and Women's Hospital, led the development of Virscan."
"Why Speed Matters in Infection Control In hospitals and clinics worldwide, bacterial infections are a major source of illness,
For that reason, many hospital-acquired infections are treated presumptively, before they are identified definitively, using broad-spectrum antibiotics.
and improving outcomes for people with hospital-acquired infections--though the effectiveness of the approach remains to be proven in future clinical trials.
In addition to helping in the clinic the new method may be useful in the food industry or for homeland security applications.
Dr. Oliver Eickelberg and Dr. Claudia Staab-Weijnitz of the Comprehensive Pneumology Center (CPC) at Helmholtz Zentrum München and their colleagues at LMU University Hospital in Munich and Yale university
has already been tested on a small sample of patients at the La paz University Hospital and in ex vivo tissues of animal models.
a consortium that wants to boost the collaboration between research centres and hospitals in the autonomous community of Madrid with the Massachusetts institute of technology (MIT) and other institutions in the Boston area (USA.
"We witnessed a LP on a 29-day-old baby that had arrived at the accident and emergency department at Boston Children's Hospital with a fever.
Madrid hospitals La paz, Quirón and San Carlos also provided significant assistance. In Boston, they worked with Massachusetts General Hospital.
Arrayto date, 300,000 euros has been invested in the project, awarded by the Madrid-MIT M+Visión Consortium.
#Disrupting tumor cell'microenvironment'suggests a new way to treat a prevalent childhood leukemia Researchers at NYU Langone Medical center
who has started already this work as a guest researcher at the Sahlgrenska Academy Hospital in Sweden."
working with colleagues at the Erasmus Medical centre in Rotterdam, have identified individual stem cells that can regenerate tissue, cartilage and bone.
#Cellular mechanism for how the body regulates glucose transport discovered UT Southwestern Medical center scientists have gleaned a key cellular mechanism of how the body adjusts glucose levels,
a gynaecologist and research associate in the Fertility Clinic and Research Laboratory on Human Reproduction at Erasme Hospital, Université Libre de Bruxelles (Brussels,
UEG's inflammatory bowel disease expert, Dr Charles Murray of the Royal Free Hospital, London, UK comments;"
In order to use protein detection for diagnostic purposes, e g. in a clinic, new, less complicated methods to study proteins are needed.
and commonly available in hospital and research labs. Since two antibodies are bound in the first step alsesignals can be avoided,
#New mechanism that attacks viral infections discovered An innovative mechanism that the innate immune system uses to control viral infections has been uncovered by researchers at the University Medical centers in Mainz and Freiburg.
"explained Professor Andreas Diefenbach of the Department of Medical microbiology and Hygiene of the Mainz University Medical center.
"Nearly all of the participants in our study had blood markers identical to patients admitted to hospital with sepsis.
researchers from Erasmus Medical center in The netherlands used a biodegradable material called Polyactive, which keeps proteins intact,
. a Mayo Clinic oncologist and lead author of the study.""We believe we have identified a mechanism that seizes the cancer's biological engine
#Discovery promises new treatments to thwart colon cancer Scientists at St jude Children's Research Hospital have discovered how an immune system protein,
#Cell that replenishes heart muscle found by researchers Regenerative medicine researchers at UT Southwestern Medical center have identified a cell that replenishes adult heart muscle by using a new cell lineage-tracing technique they devised.
and will now be tested in a larger trial involving three hospitals in London. Researchers analysed breath samples of 210 patients using the test.
Now, 400 patients at UCLH (University college London Hospitals NHS Foundation Trust), The Royal Marsden NHS Foundation Trust,
In collaboration with Pr Véronique Del Marmol (Department of Dermatology, Erasme Hospital, ULB) and the group of Pr François Fuks (Laboratory of cancer epigenetics, Faculty of medicine, ULB), Larsimont and colleagues demonstrated that
M d.,lead author of the study and director of the clinical retina research unit At wills Eye Hospital."
#First hospital light fixture to kill bacteria safely, continuously becomes commercially available in North america Indigo-Clean#is a light fixture manufactured through an exclusive licensing agreement with the University of Strathclyde in Glasgow, Scotland,
a large teaching hospital operated by NHS (National Health service) Greater Glasgow and Clyde. The technology and its effectiveness have been the subject of more than 20 peer-reviewed academic publications and 30 conference presentations since 2008.
"The Centers for Disease Control and Prevention (CDC) reports around 1 in 25 hospital patients in the US have at least one infection contracted in the health care setting.
and 99,000 deaths in acute care hospitals in the U s. and add $35-45 billion in excess health care costs each year.
HAIS can also result in significant financial penalties for hospitals under the Affordable Care Act.
those providers scoring poorly in the Hospital-Acquired Condition (HAC) program receive lower Medicare reimbursements.
With this knowledge, researchers can now test ER-stress blocking drugs in the clinic, and carry out fundamental research on how different types of pain grouped under the name"neuropathic"differ from each other
"says Dr. Kim who is also Professor of Surgery at Case Western Reserve University School of medicine and the Charles Hubay Chair at UH Case Medical center."
The new Phase I clinical trial is being supported by University Hospitals as well as a significant philanthropic effort including the Immunogene Therapy Fund, Paula and Ronald Raymond Fund and the Kathryn and Paula Miller Family Fund."
researchers at Boston Children's Hospital and Harvard Medical school have restored hearing in mice with a genetic form of deafness.
a specialist in genetic hearing loss at Boston Children's Hospital who is familiar with the work."
as well as Tang Du Hospital in China, University of the Negevin, Israel, and the Instituto Neurologico C. Besta in Italy.
Cory Abate-Shen (Columbia University), Nima Sharifi (Cleveland Clinic) and Jeffrey Karnes (Mayo Clinic), and contributions from Genomedx.
"We are enthusiastic about the next step of clinical assessment for testing DNA-PKCS inhibitors in the clinic.
Oliver Eickelberg, Chairman of the Comprehensive Pneumology Center (CPC) at the Helmholtz Zentrum München and University Hospital of the Ludwig-Maximilians-Universität
The protection allowed the researchers to safely give a dose 16 times higher than they could with the formulation now used in cancer clinics,
Mason Freeman, Massachusetts General Hospital; David Bushinsky, University of Rochester; and Martha Mayo, Dahlia Garza, Yuri Stasiv, Rezi Zawadzki and Lance Berman, from Relypsa a
including investigators from the University of Mississippi Medical center (UMMC), has identified a gene that underlies healthy information processing--a first step on a complicated road to understand cognitive aging and age-related diseases, such as Alzheimer's disease.
"said Dr. Carla Ibrahim-Verbaas, a resident in neurology at Erasmus University Medical center in Rotterdam, The netherlands,
It will only be available in the Ebola Treatment Units, not the hospitals,"Sakoba Keita,
More than half of South korea's infections have been traced to a hospital in Pyeongtaek city, 65 km (40 miles) southwest of Seoul, where the man shared a room with another patient."
Officials have not identified the hospitals where MERS patients are being treated, but the Pyeongtaek facility has been shut
His visit to us was just unavoidable exposure to other people in the hospital,"the nurse,
When the man was admitted at another hospital, where he was diagnosed finally, he at first only told staff he had visited Bahrain,
"said an official at the hospital where he was diagnosed on May 20, who also declined to be identified."
He is in hospital in China. As of Wednesday, the index patient was on a respirator in a government-designated hospital.
The fund will also bring in mentors from Manipal Hospitals, Narayana Health, and Pfizer. he devices could become the new standard of care for breast screening in India and other low-resource markets around the world.
fatigue or even tremors after a long day at the hospital can make things challenging,
is currently being tested at Sickkids Hospital, and researchers are hoping that the technology might soon lend a helping hand to surgeons around the country.
from the Children Hospital of Los angeles (CHLA) took a step forward and ordered a fully-3d model of his patient heart. s useful as scans are for visualizing structural defects,
currently performed at only a handful of pediatric hospitals in the US. Studying the heart model allowed Kim to accurately plan the procedure
associate professor of biomedical engineering at Columbia Engineering and of radiology at Columbia University Medical center (CUMC), has developed a new microscope that can image living things in 3d at very high speeds.
#Smart devices track hand-washing in hospitals to help reduce the spread of infection In fact,
and Philip Liang SM 6 is using smart devices to monitor hand hygiene among hospital staff
Currently, the Royal Brompton and Harefield hospital in London is studying the correlation between the Medsense system and reduction in HAIS.
wee trying to be a support system for the hospital. In the atient zone Medsense consists of four smart devices,
In 2011, researchers at Queen Mary Hospital in Hong kong published a paper in the journal Biomed Infectious disease that found Medsense was 88 percent accurate in monitoring staff compliance with THE WHO guidelines.
and Medsense has been trialed in 10 hospitals across the United states and Europe, and in Saudi arabia, Bahrain, and Qatar.
as the wearers move through the atient journeythe waiting room, pre-procedure, procedure, and recovery room. General Sensing creates digital floor maps of an area being studied;
Another possible application is real-time location of surplus staff particularly important when there a sudden influx of patients in one area of a hospital,
the multidisciplinary team also included Michel Gilliet of Switzerland Lausanne University Hospital, and Jure Dobnikar and Daan Frenkel of the University of Cambridge.
Researchers at Case Western Reserve and UT Southwestern Medical center this week announced that they have taken significant steps toward turning this once-improbable idea into a vivid reality.
the Ingalls Professor of Cancer Genetics at the university School of medicine and a medical oncologist at University Hospitals Case Medical center Seidman Cancer Center. e have developed a drug that acts like a vitamin for tissue stem cells,
from the Harrington Discovery Institute at University Hospitals, and from multiple National institutes of health grants that included the Case GI SPORE,
and the National Center for Accelerating Innovation at the Cleveland Clinic. Additional support was received from the Marguerite Wilson Foundation;
if a tissue is cancerous, according to researchers from the Department of energy Oak ridge National Laboratory and Brigham and Women Hospital/Harvard Medical school.
Long before those uses reach the clinic, however, gene editing will be used to probe the role of genes,
#Pioneering gene therapy takes aim at inherited blindness Canada first human gene therapy trial for eyeshe replacement of a faulty gene with a healthy ones now underway at the Royal Alexandra Hospital to preserve
such as in hospitals, in manufacturing facilities and in airplane cabins. Visible light communications has the potential to significantly increase the speed of Internet connection in multiuser indoor environments due to the broad bandwidth of the visible light,
said Annabi. e see great potential for use in the clinic. Our method is simple,
said Dr. James K. Min, director of the Dalio Institute of Cardiovascular Imaging at Newyork-Presbyterian Hospital/Weill Cornell Medical center,
In collaboration with researchers from Emory University School of medicine in Atlanta and Cedars-Sinai Medical center in Los angeles, the researchers reviewed medical records of 9, 715 patients in the area surrounding Nashville, Tennessee,
who were referred by their primary care physicians to a single outpatient clinic from 1996 to 1999.
researchers at Boston Children Hospital and Harvard Medical school have restored hearing in mice with a genetic form of deafness.
a specialist in genetic hearing loss at Boston Children Hospital who is familiar with the work. ochlear implants are great,
and Beth Israel Deaconess Medical center demonstrates that a heterologous prime-boost HIV-1 vaccine regimen protected 50 percent of vaccinated nonhuman primates against challenges with the simian immunodeficiency virus (SIV),
Mekhail team also found that the DNA hospital, also known as the nuclear pore complex, repairs damaged DNA inaccurately.
Now, researchers at MIT Koch Institute for Integrative Cancer Research and Massachusetts General Hospital (MGH) have created a polymer gel that overcomes this safety concern
will enter the clinic in the future. here actually well-trodden ground putting modified T cells into patients.
Oren Shibolet, Head of the Liver Unit at the Tel-aviv Sourasky Medical center, who was involved not in this study. he method provides access to unlimited amounts of functional liver cells
Further, researchers from the team of Jean-Pierre Bourquin from the University Children Hospital in Zürich
using both tests to assess 106 suspected Ebola patients at two clinics in Sierra leone as well as 284 previously collected blood samples.
an infectious disease doctor at Boston Children Hospital, told Science. t was more sensitive than I expected for a rapid antigen diagnostic test. his test can be done in very austere environments,
from the group of Miguel Nicolelis at the Duke university Medical center in Durham, North carolina. In the first, the researchers used electrodes to link the brains of three monkeys to a computer
who developed the technique working with the company Cinogy and the Department of Dermatology, Venereology and Allergology at the University Medical centre Göttingen.
Ray Flynn, 80, had the Argus II device implanted during a four-hour procedure carried out by Prof Paulo Stanga at Manchester Royal Eye Hospital.
and Women Hospital showed that Americans worry that insurance companies and employers may discriminate against them based on their family histories or genetic test results.
If clinics could tell patients whether they should save their money or go directly to high-cost interventions,
fertility clinics could also look to see if these 648 RNA elements are present in the semen."
and chief of inpatient and critical care pediatrics at The University of Vermont Children's Hospital.
The two have known each other for 26 years, crossing paths as young pediatricians and then as co-workers at the University of Vermont Medical center.
Finette decided on a major diversion from his work at UVM Medical center as a researcher and in the emergency room critical care unit for children."
Dr. Jill Ostrem, a neurologist at the University of California San francisco Medical center, commented t totally novel.
And Juno partner, Seattle Children Hospital, has started just a Phase 1 CAR-T trial for children with neuroblastoma,
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