and the road to such a drug is long and far from simple
#Researchers test smartphones for earthquake warning The study, led by scientists at the U s. Geological Survey
to test a pilot hybrid earthquake warning system comprising stand-alone smartphone sensors and scientific-grade sensors along the Chilean coast."
#Taking aircraft manufacturing out of the oven Aerospace engineers at MIT have developed now a carbon nanotube (CNT) film that can heat
The group tested the film on a common carbon-fiber material used in aircraft components,
"Typically, if you're going to cook a fuselage for an Airbus a350 or Boeing 787, you've got about a four-story oven that's tens of millions of dollars in infrastructure that you don't need,
mainly for deicing airplane wings. The team recognized that in addition to their negligible weight, carbon nanotubes heat efficiently
In experiments, Wardle and his team integrated the film into airplane wings via conventional, oven-based curing methods,
In initial experiments, the researchers investigated the film's potential to fuse two types of aerospace-grade composite typically used in aircraft wings and fuselages.
"The team is working with industrial partners to find ways to scale up the technology to manufacture composites large enough to make airplane fuselages and wings."
"Gregory Odegard, a professor of computational mechanics at Michigan Technological University, says the group's carbon nanotube film may go toward improving the quality and efficiency of fabrication processes for large composites, such as wings on commercial aircraft.
and that approach is likely to provide enormous benefit down the road, "said Tesar, also a New york Stem Cell Foundation Robertson Investigator and member of the National Center for Regenerative medicine."
It could be integrated with existing Wi-fi systems to reduce bandwidth problems in crowded locations, such as airport terminals or coffee shops,
such as airport terminals or coffee shops, and in homes where several people have multiple Wifi devices. Experts say that recent advances in LED TECHNOLOGY have made it possible to modulate the LED light more rapidly,
and that approach is likely to provide enormous benefit down the road, "said Tesar, also a New york Stem Cell Foundation Robertson Investigator and member of the National Center for Regenerative medicine."
The modeling of these arrangements could inform the cluster's use as a transporter of pharmaceutical drugs
as we can easily install this system into a drone, airplane, or satellite to detect plant photosynthesis on a large scale to assess ecosystem health,
and fuse with the blood-brain barrier to deliver their cargo across it.""Catalase counteracts the effects of free radicals,
including transportation, where centimeter-accurate GPS could lead to better vehicle-to-vehicle communication technology."
and velocity of an approaching car that is blocked from view by other traffic, your car can plan ahead to avoid a collision,
who is now a postdoctoral scholar at Cold Spring Harbor Laboratory.""The most critical result of our work here is that we can track a single decision
"From the theoretical study, we have identified the most detrimental defects that hinder the electron transport in thallium sulfide iodide
Previous experimental studies have shown the material's good carrier transport properties, indicating great potential for future development.
A good radiation detection material should have efficient charge transport property, Du said. Native defects, the natural structure flaws in a semiconductor,
thus harming the carrier transport process. Studying the native defects and their effects on charge transport in a material are hence essential for the performance improvement of a radiation detector.
In the study, Du and his co-worker, Hongliang Shi, another researcher from Oak ridge National Laboratory, used a theoretical modeling method called density functional calculation to study native defects,
The researchers'next step is to study impurities, impurity-defect complexes and their effects on carrier transport in thallium sulfide iodide e
production of methane emissions and odors) make necessary to search for other waste management routes. It is highlighted the thermal treatment through pyrolysis for large scale production of biochar
The building block, called the Passenger-associated Transport Repeat (PATR), has been found in virulence factors of many major harmful bacteria including Salmonella, Shigella,
The PATR was shown to be integral in the transport of the virulence factors to the surface of the bacterial cell,
Raman spectroscopy and transport measurements on the graphene/boron nitride heterostructures reveals high electron mobilities comparable with those observed in similar assemblies based on exfoliated graphene.
this is accomplished by synchronizing the projector so that as the laser scans a particular plane, the camera accepts light only from that plane.
Alternatively if other camera hardware is used, the mathematical framework developed by the team can compute energy-efficient codes that optimize the amount of energy that reaches the camera.
Arraytheir medical diagnostics device is designed to harness centrifugal force--akin to the circular swing of A chair-o-Plane"carnival ride
"Our pilot study brings us a step closer toward realizing this vision, "said Neugebauer. The team will continue toward its goal of developing an easy-to-use spectroscopy-based point-of-care medical device for fast and reliable diagnostics."
an airplane or a farming tool and appreciate the durable layers protecting its parts. But depositing this covering is an essential manufacturing step that allows machines to function with repeated use."
This allowed transport into the nucleus of a protein called Smad2, which is essential for TGF-beta to exert its effects on astrocytes.
In other experiments, the scientists showed that eliminating p75ntr from astrocytes blocked the transport of Smad2 into the nucleus."Nuclear pores are gatekeepers
and frosting on aircraft wings.""This represents a fundamentally new concept in engineered surfaces, "said Tak-Sing Wong, assistant professor of mechanical engineering and a faculty member in the Penn State Materials Research Institute."
without altering the enzyme itself--establishing a new route for enzyme engineering and demonstrating the versatility of these synthetic proteins.
The gene defect causes the absence of a protein variant involved in the transport of essential enzymes into structures in the cell called peroxisomes.
The failed transport of these enzymes affects the levels of two specific fat variants in the cell, plasmalogenes and phytanic acid.
Today, scientists at Cold Spring Harbor Laboratory (CSHL) publish a new interactive analysis program called Gingko that reduces the uncertainty of single-cell analysis
"Cold Spring Harbor has established itself as the world leader in single-cell analysis, "says Schatz."
what is called potassium transport. A follow-up experiment showed that new intestinal cells treated with E. histolytica showed potassium efflux--the flow of potassium from inside a cell out through the cell wall--directly before cell death."
and used drugs to block their ability to transport potassium. Blocking potassium efflux created cells that were resistant to E. histolytica."
"Our study shows that genome mining is not only a viable route to new natural products, but that there are a tremendous number of new compounds awaiting discovery from the genomes of microbial strains,
"Because the lung is a potential entry route for infection into the body, its immune response is developed highly.
"This development seems to offer a route which means others won't have to suffer in this way and from a personal perspective
By 2020, the EU aims to have 10 per cent of the transport fuel of every EU country come from renewable sources such as biofuels.
the UVM team was able to observe nanoscale defects and boundaries in the crystal grains in the thin films of phthalocyanine--roadblocks in the electron highway."
"Think of these as easy-on ramps onto a highway--instead of an awkward stop sign at the top of a hill--that allow excitons to move far and fast.
This allows organic thin films to carry energy along this molecular highway with relative ease,
#Coordinating traffic down the neuronal highway An international team of researchers, led by scientists at the National University of Singapore (NUS),
and the University of Michigan (U-M). They identified and characterised a protein that transports the enzyme ACL to the tips of neurons,
marking ACL for transport by the enzyme kinesin-1 to the neuron terminals. Once there
The researchers showed that a BNIP-H mutant associated with Cayman ataxia caused defects in the transport of the ACL enzyme.
The tiny cargo-filled sacs then attach to the sperm like decorations on a Christmas tree before the sperm fuses with the egg.
"Discovery of these oviductosomes provides us with a window into the cargo being delivered by the female to the sperm,
"Currently, Deleon and her team are analyzing the protein-rich contents of this cargo to find out exactly what gives the sperm
#Coordinating traffic down the neuronal highway An international team of researchers, led by scientists at the National University of Singapore (NUS),
and the University of Michigan (U-M). They identified and characterised a protein that transports the enzyme ACL to the tips of neurons,
marking ACL for transport by the enzyme kinesin-1 to the neuron terminals. Once there
The researchers showed that a BNIP-H mutant associated with Cayman ataxia caused defects in the transport of the ACL enzyme.
which will guide how scientists and engineers build aircraft components, for example. The research, led by Jianwei (John) Miao,
and deliver their cargo, they could break down into additional therapeutic agents. We can now design two things into one."
The use of either preferred or non-preferred codons is like having speed signs on the protein production highway:
the development of new, lighter and stronger materials spanning consumer electronics to aircraft; and faster information searching through large databases s
"What we see is that there is a lot of diversity in the transport properties of these pores,
and in understanding transport through these really small pores in ultrathin materials,"Karnik says s
seizure disorders and many other conditions affecting the brain and nervous system down the road.""Using nasal mucosal grafting,
"By mapping it to the plane we were able to follow cells in a heartbeat,
They investigated cell lines to determine the role played by VRAC and its subunits in the transport of cisplatin and carboplatin into the cell.
Apparently, the VRAC subunit LRRC8D is immensely important for the transport of the amino acid taurine,
The project run by CITIES Foundation recently launched their pilot scheme in Amsterdam Noord. WASTED is a three-part system
which include free beers, discounts on groceries and 50 percent off of bike repairs. Individuals, collectives and schools can also take advantage of a free educational package
but it definitely never hailed a cab. Oh, and back to the portability issue. Don fret,
but the powertrain system, which includes the engine, also accounts for a large proportion of the vehicle weight.
and manager of the research area Lightweight Powertrain Design at the Fraunhofer Project Group for new drive systems. he cylinder casing weighs around 20 percent less than the equivalent aluminum component,
#Computer-Designed Rocker Protein Worlds First To Biomimic Ion Transport For the first time, scientists recreated the biological function of substrate transportation across the cell membranes by computationally designing a transporter protein.
and cell signaling, for instance, between nerve cells in the brain and spinal cord. o our knowledge, this is the first transport protein designed from scratch that is,
and the engineered system works like natural transport proteins found throughout the human body. Rocker was designed to perform this function by doing one thing ockingbetween two different shapes, or conformations.
Like a gatekeeper, the engineered transport protein controls what moves in and out of the cell from one side of the membrane to the other. ill Degrado and his postdoc
Nathan Joh, hypothesized that the complex transportation function could be generated through engineering of this simple ockingmotion,
mechanisms and interactions of known transporters to overcome several barriers in protein engineering, including membrane protein folding.
I like to use enhanced sampling techniques to more fully capture the entire transport process using Stampede resources,
making sure that the transporter that youe made ends up in the right place at the right time.
the technology enables swarms of compact UAVS to take off from ships, tactical vehicles, aircraft or other unmanned platforms.
Another technology demonstration of nine UAVS accomplished completely autonomous UAV synchronization and formation flight. ONR officials note that
able to step in and take control as desired. his level of autonomous swarming flight has never been done before,
and reconfigurable will manned free aircraft and traditional weapon systems to do more, and essentially multiply combat power at decreased risk to the warfighter.
Even hundreds of small autonomous UAVS cost less than a single tactical aircraft and officials note, having this capability will force adversaries to focus on UAV swarm response.
which stands for cytometry by time-of-flight, and it gives researchers greater insight into the intricacies of immune cells than ever before.
and our knowledge in ionic and electronic transport mechanism in these films says Professor Nini Pryds.
The team used mouse models of asthma and human airway tissue from asthmatic and non-asthmatic people to reach their findings.
These symptoms include airway narrowing, airway twitchiness and inflammation all of which contribute to increased breathing difficulty. ur findings are said incredibly exciting
from the School of Biosciences. or the first time we have found a link airways inflammation,
cigarette smoke and car fumes and airways twitchiness in allergic asthma. ur paper shows how these triggers release chemicals that activate Casr in airway tissue
and drive asthma symptoms like airway twitchiness, inflammation, and narrowing. Using calcilytics, nebulized directly into the lungs,
the identification of Casr in airway tissue means that the potential for treatment of other inflammatory lung diseases beyond asthma is immense.
the Cardiff Partnership Fund and a BBSRC parking Impactaward d
#Transparent Armor based on Spinel Could Also Ruggedize Your Smart Phone Imagine a glass window that tough like armor,
onformal with the surface of an airplane or UAV wing, depending on the shape of the press.
The military also interested in using spinel to better protect visible and infrared cameras on planes and other platforms.
His lab also makes lightweight, inexpensive fibers for infrared countermeasures applications on helicopters and other platforms.
he delivery of the second flight laser is a major achievement by Selex-ES, who have overcome major technology issues along the way. he contributions of Airbus Defence and Space,
Migration along a gradient, called a taxis, is found all over nature. The daily vertical migration of marine plankton toward sunlight, is one example,
Another component functions as a avigator, planning out a route to meet mission goals. The last component works as a octor,
Researchers may have discovered first gene delivery system that efficiently penetrates the hard-to-breach human airway mucus barrier of lung tissue.
and Federal University of Rio de janeiro in Brazil have designed a DNA-loaded nanoparticle that can pass through the mucus barrier covering conducting airways of lung tissue proving the concept,
asthma and other life-threatening lung diseases. o our knowledge, this is the first biodegradable gene delivery system that efficiently penetrates the human airway mucus barrier of lung tissue,
inhaled matter is trapped typically in airway mucus and subsequently swept away from the lungs via beating activities of cilia,
His team experiments with human airway mucus and small animals, Suk adds, were designed as a proof-of-concept study demonstrating that placing corrective
but it also makes the airway mucus harder to overcome by inhaled therapeutic nanoparticles. Most of the existing drugs for CF help clear infections but do not solve the disease underlying problems.
in this case the mucus covering the lung airways. In other words, conventional nanoparticles are too sticky to avoid unwanted off-target interactions during their journey toward the target cells.
rendering them too large to penetrate the mesh of airway mucus. For its design, the team developed a simple method to densely coat the nanoparticles with a nonsticky polymer called PEG,
and are capable of rapidly penetrating human airway mucus freshly collected from patients visiting the Johns Hopkins Adult Cystic fibrosis Program directed by Michael Boyle,
During that time, the team took time-of-flight pictures of the distribution of atoms to capture the topology
or stress levels in soldiers and pilots. In this study, engineers focused on uric acid, which is a marker related to diabetes and to gout.
and frosting on aircraft wings. his represents a fundamentally new concept in engineered surfaces, said Tak-Sing Wong,
but also in transportation industry power backup, micro grid storage, and for the wider use of renewable energy. OSU officials say they are seeking support for further research
are durable, reusable and easy to package, transport and ship. Unlike small chemical tablets that dissolve in water and leave a chlorine aftertaste, Madidrop is made of a continuously reusable ceramic that is simply placed in a water vessel,
They observed that the function a protein involved in the transport of proteins and organelles within cells (called ab8, was affected,
Frommer and his lab have worked extensively on the family of SWEET sugar transporters, which play several key roles in plants,
which encodes a sugar transporter protein in maize, was shown to be expressed specifically in the maize seed by the group of Prem Chourey at University of Florida,
But there remains a lot of work to be done toward developing miniature navigation systems, particularly for confined spaces.
and placed on the Transmedics device for transport to the recipients. The team results are unpublished.
serving live traffic, next year. Kumu is also working on a chip that will make it possible to shrink down the package containing the company technology from roughly the size of a hardback book to something more akin to a credit card.
The biggest takeaway from the tweets is the mention of a"market pilot re-route,
The speed of transport through the system, from muscular ripples along the intestines called peristalsis can vary widely from person to person;
when a patient carries a heavy suitcase through an airport, she said r
#lipperysteel provides both durability and antifouling Researchers from the Harvard John A. Paulson School of engineering and Applied sciences (SEAS) have developed a new coating for steel,
This increased the efficiency of both photon absorption and electron transport. It was found that as well as increasing the transport of electrons by creating efectsin the bismuth vanadate,
the nitrogen also lowered the energy needed to kick electrons into the state in which they were available to split water.
Dai added that lithium batteries could o off in an unpredictable mannerand cited a ban by US airlines Delta
and United on bulk shipments on passenger planes. And the new design could be used to store renewable energy of the electrical grid, the researchers suggested.
shopping, but this extends to maps, flights and news), to issues with Google scraping and fencing of datasets, often exclusively and at unmatched scale.
#Can the internet of things save us from traffic jams? Traffic is getting worse. It doesn just feel that way,
the stats prove it: commuters in 2014 spent an average 66 more hours stuck in traffic than they did in 2013, according to navigation tech firm Tomtom.
So when internet of things technology is disrupting every part of our lives, when will traffic lights be rebuilt rethought and?
Well, the traffic light revolution is already underway. It is all part of the promise of connected and self-driving cars,
which allow data about individual journeys, routes and vehicles to be monitored centrally, controlled and systematised.
Autonomous intersection management Once computers are in full control of our cars, do need we even traffic lights at intersections?
That the idea behind AIM autonomous intersection management at the artificial intelligence laboratory at the University of Texas at Austin.
But it won be fainthearted for the at least not until passengers have learnt to entirely trust their automated pilots:
For the idea to work, it would require roads to be mostly full of autonomous cars, says project leader Professor Peter Stone
The researchers compared AIM to heavy traffic on a major road, saying it would reduce delay by as much as 100 times though that only at intersections, not total driving time.
but also used anonymised data from third party navigation apps, including smartphone maps. e have agreements with a number of smartphone manufacturers,
says Nick Cohn, senior traffic expert at Tomtom. It also gathers data from telematics units installed in fleet vehicles as well as in-dash systems
and for deciding whether they need to switch to a different traffic signal scheme, Cohn says.
not only GPS from cars and timings from traffic lights, but also air quality sensor data and images from cameras. n its own, each is of low value,
he says. t might be to turn some traffic lights green quicker or send a text message to a car,
Highways England used to simply warn there were ueues ahead but now tells drivers it will be 17 minutes to their junction, points out Giles Perkins, business development director for intelligent transport at Mouchel,
which runs the National Traffic information service. ore data in and more data out can only be a good thing.
Unintended consequences Though traffic data makes it possible to see the movement of traffic in real time,
and traffic lights themselves are operated algorithmically, it is still not possible to engineer a way of turning the lights green as you pull up. t easy to change the traffic lights, ssays IBM Standford-Clark. ut...
you get this terrible interconnection of unintended consequences. Your main route into a city may be clear,
but every road feeding into it would be gridlocked. t not a trivial thing to do.
One way self-driving vehicles may be introduced is latooning with a lead car in control of a train or group of followers, handy for giving lorry drivers a break.
chief scientist and research director at transport firm TRL. ither the platoon could signal that it cleared the intersection
There, traffic lights are alkingto motorists, sending messages to a device in car about obstacles or delays ahead,
if they travel at 24 miles an hour they will hit the next four sets of traffic lights on green,
says Newcastle University professor of intelligent transport systems Phil Blyte, announcing the project. n more congested areas or particularly busy times of the day,
then vehicles on key roads might be given priority in order to keep the traffic flowing. The system also gives priority to non-emergency vehicles,
So far, 20 traffic lights are using the system in Newcastle city centre. Zombies ahead and cyclists As with any tech innovation, one of the biggest challenges is security.
The best example so far is hacked surely construction signs in the US with attackers warning of zombies ahead,
roads aren used only by cars. What about the bicycles, scooters and pedestrians hoping to cross the street?
They have smartphones, so there otential to do something with that, said Tomtom Cohn. think it be great as a pedestrian and a cyclist if
I didn have to push a button to cross and I didn have to wait, that
or route when I walking or cycling. That raises a question: what the goal of Iot-connected traffic lights?
don think the main reason is going to be racing people through intersections, it going to be said safety applications
boost public transport or improve safety, or is there some other goal we haven thought of yet? here a whole bunch of optimisation goals which may not be the ones you first thing of,
The best way to achieve it may not be via smart, reactive traffic lights, but by sending messages to drivers in cars,
and nudging them into better routes. t probably easier to change driver behaviour than it is to change the traffic lights.
and is experimenting with a high-speed public transport system called Hyperloop. Musk also unveiled a larger owerpack a 100kwh battery block to help utilities smooth out their supply of wind and solar energy
An avid cyclist who wore padding when using BMX bikes, he wanted to create more flexible protection than stiff sportswear
which typically involves foam and a rigid plastic protector to cover body parts. hen you put on the sportswear,
The technology allows for what the scientists call ontainerless transportation which could find uses in applications where material is dangerous to handle,
twisters or bottles emerge as the optimum mechanisms for tractor beams or containerless transportation. Here's how Bristol University explains one goes about making acoustic pincers:
According to Cisco, about half (46 percent) of total mobile data traffic was offloaded through Wi-fi in 2014,
if 90 percent of traffic went over Wi-fi instead of cellular, it could save consumers $700 billion each year.
Arbor networks said the attack had traffic of up to 334 Gbps, accounting for tens of thousands of connections, targeting one Asian network operator.
or company with a flood of traffic, bringing their systems to a halt. But it's rare to see an attack driving so much traffic.
These attacks leverage a technique that amplifies the traffic attackers generate through hijacking computers'bandwidth,
It will help us make parts that are stronger lighter and function better for more energy-efficient transportation and energy production applications such as cars and wind turbines.
The study--authored by scientists from the U s. Department of energy's Brookhaven National Laboratory Stony Brook University Cold Spring Harbor Laboratory
and expertise said study coauthor Bruce Stillman of Cold Spring Harbor. Imperial College and Cold Spring Harbor handled the challenging material preparation
and functional characterization while Brookhaven and Stony Brook led the sophisticated molecular imaging and three-dimensional image reconstruction.
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