The protein acts a bit like a tap to increase or reduce the production of natural compounds depending on how much of the protein is present.
the natural product ilicifoline B, no comparison with a petrochemical route was possible as this substance had never before been synthesized in a laboratory.
the new xylochemical synthesis turned out to be significantly more efficient than any previously known route based on petrochemistry."
Transport and protect drugs Jensen has completed just her Ph d. work on how to use lipids from the cell membranes of extremophilic microorganisms to design drug carriers that transport
Liposomes are available in many different forms-some are used e g in cosmetics to transport nourishing substances into the skin.
They observed that the function a protein involved in the transport of proteins and organelles within cells (called'Rab8'),was affected,
#3-D printed fetal head helps manage care for baby with life-threatening airway mass Megan Thompson was about 30 weeks pregnant
whether the mass would block Conan's airway after birth. The 3-D printed model of the fetus allowed us to actually see in person what it looked like
"This is the first case we are aware of that 3-D printing has helped show how severe an airway risk in a fetus was
so that a surgeon can establish an airway to allow the baby to breathe. Instead, Conan was born via a scheduled C-section."
At one end of that plane there is a so-called quantum dot: a tiny trap for electrons, only a hundred nanometers wide, in which owing to quantum mechanics the electrons exist in well-defined energy states similar to those of an atom.
releasing their drug cargo into the brain tumors. In testing with mouse models of aggressive brain tumors, the technology took out far more cancer cells, inhibited tumor growth better and extended life longer than traditional chemotherapy delivery.
whether for an airplane, car, bridge, mobile device, or biological implant, engineers strive to make the material strong
ride steel subway cars over steel rails to our offices in steel-framed building. Steel screws hold together broken bones,
or take a different route
#Researchers develop drug delivery technique to bypass blood-brain barrier Researchers at Massachusetts Eye and Ear/Harvard Medical school and Boston University have prevented successfully the development of Parkinson's disease in a mouse using new techniques to deliver drugs across the naturally impenetrable blood-brain barrier.
seizure disorders and many other conditions affecting the brain and nervous system down the road.""Using nasal mucosal grafting,
Eye and Ear is a Harvard Medical school teaching hospital and trains future medical leaders in ophthalmology and otolaryngology, through residency as well as clinical and research fellowships.
the same way salt helps melt snow and ice on our roads after a blizzard.
#Solar-powered plane lands in Ahmedabad on second leg of world trip A Swiss-made solar powered aircraft landed in Ahmedabad on Tuesday night,
The Solar impulse 2 touched down at Ahmedabad airport in Gujarat about 16 hours after it took off from Muscat, Oman, for the 1,
The world's first aircraft powered by solar energy was to remain in Ahmedabad for two days before flying to the holy city of Varanasi on Saturday.
The swiss pilots Bertrand Piccard and Andre Boschberg, are taking turns at the controls of the aircraft during their 35,000-kilometer (21,700-mile) journey.
The aircraft's wings are covered by more than 17,000 solar cells that recharge the plane's batteries.
It flies ideally at around 25 knots, or 45 kph (28 mph). On Monday, Borschberg, who co-founded the Solar impulse company that built the plane,
flew the Si2 from Abu dhabi, the capital of United arab emirates, to nearby Oman in the first leg of the epic journey.
Both pilots have been training hard for this journey, which will span 25 flight days over five months.
Borschberg has been practicing yoga and Piccard self-hypnosis. Neither pilot will be able to stand in the cockpit while flying
but the seat reclines for stretching and its cushion can be removed for access to a toilet.
if the plane isn't flying level. The SI2 aircraft has a wingspan of 72 meters (236 feet),
spanning larger than a Boeing 747 jumbo jet. At about 2, 300 kilograms (5, 070 pounds), the Si2 weighs about as much as a minivan or mid-sized truck.
which have relied typically on networks of thousands of sales points in airports, post offices and shops.
Ola due to high encryption codes, say ISPS Dot had issued a letter to Internet service providers (ISPS) asking them to block websites of taxi operators Uber,
Taxiforsure and Ola Cabs, following a request from the Delhi government. However, websites are still accessible to all.
ISPS now say they are unable to block taxi aggregator websites Ola and Uber due to high encryption codes.
Ola Cabs and Taxiforsure continue to book passengers through their apps. All app-based cab services were banned in the national capital last year after a driver of Uber,
the US-based online taxi-hailing company, was accused allegedly of raping a female passenger e
#MIT researchers announce new transistors for more power efficient electronics A material called gallium nitride (Gan) is poised to become the next semiconductor for power electronics,
enabling much higher efficiency than silicon. Massachusetts institute of technology spin out Cambridge Electronics Inc (CEI) has announced a line of Gan transistors and power electronic circuits that promise to cut energy usage in data centres, electric cars,
expiring, damaged or unsellable fresh produce and transport it to the processing facility, where it will be turned into freeze-dried powder.
added Jarolimkova. emoving water and storing the produce as powder will allow for maximum utilization of space during transport and storage as well as significantly prolonged shelf life.
While at the moment they still have to rely on station staff to assist them on to their train,
The app, called Wayfindr, uses Bluetooth and beacon technology to trace the user location in the subway
whom have difficulty using London transport network independently. This kind of technology could help them feel empowered and more confident about their capabilities.
This is why United airlines and Delta air lines banned bulk lithium battery shipments on passenger planes. When Stanford drilled through its aluminum battery pouch
A report just issued by the University of Michigan Transportation Research Institute, suggests a similar problem could befall those riding in autonomous-driving cars.
allowing for more efficient and cleaner transportation of energy. But network expansion will also be necessary,
Crossy Road and Zig Zag. On some level, it heartwarming that these faux naif, Eighties throwback titles thrive.
and territories were decided upon by the TEEP selection committee comprised of some of Africa distinguished industry captains
such as having a pilot on hand to fly the drone at all times. That important, because Amazon wants its Prime Air drones to be autonomous.)
and even drone pilots, too. So. Let say drone delivery actually happens, with Amazon taking the lead.
One drug-toting drone infamously crashed in a parking lot in January. And legal drugs are being delivered in other countries,
two of the first ten drone flights were scrapped because of bad weather. Would-be drone delivery services in the United states face complications, too.
or sticker along with a text message and the money, enter in an amount that is currently less than $250 and tap the aybutton.
Even surgery can now be taught remotely with technologies that combine virtual reality with AI techniques to train both real time decision-making and psychomotor skills.
what Uber is to taxis: a new slant on an old industry that leverages data and analyticsnd puts power in the hands of its customers.
while future uses may include larger endeavors like hiding ships, aircraft, and convoy vehicles from enemy radar r
Material testing procedures that regularly check for fissures in rail tracks or aircraft support structures also rely on ultrasound.
For example, an unpiloted air vehicle might change shape from one designed for a cruise mission to one designed for a dive.
A new assistive device for blind people taps into this sensory network. It translates images into sounds,
The treatment, interleukin (IL)- 2 combined with imiquimod and topical retinoid therapy, is a promising option for patients with so-called n-transit metastases.
this is accomplished by synchronizing the projector so that as the laser scans a particular plane, the camera accepts light only from that plane.
Alternatively, if other camera hardware is used, the mathematical framework developed by the team can compute energy-efficient codes that optimize the amount of energy that reaches the camera. e have a way of choosing the light rays we want to capture
no faster than 100 mph (161 km h) and remain within the pilot's line of sight, among a raft of other conditions relating to safety and maintenance.
where general aviation begins. It plans to shoot autonomous drones along 10 mi (16 km) long skyways at 50 mph (80.5 km h) with packages weighing up to 55 lb (25 kg) in tow.
"Knothe Tate has used already the system to demonstrate a link in osteoarthritic guinea pigs between disease status and molecular transport through blood, muscle, and bone.
#Overview of a Smart Optical Time-of-Flight Sensor Technology With billions of sensors already being deployed in all types of devices and applications,
Combined with the use of visible or infrared LEDS to perform time-of-flight measurements,
Time-of-Flight Principle Leddar sensors use LEDS to generate very short light pulses, typically 100,000 pulses per second.
The time-of-flight (Tof) principle essentially consists in measuring the time taken by a light pulse to travel from the sensor to a remote object
and designing new routes to charge and energy flow at the nanoscale. What is exciting to me about this field is its multidisciplinary nature the need for both physics and chemistry and the strong beneficial coupling between experiment and theory.
it's in supersonic passenger flight. With the grounding of the Concorde fleets in 2013, flying faster than the speed of sound reverted to a military monopoly,
Now Airbus'Marco Prampolini and Yohann Coraboeuf have been granted a US patent for an"ultra-rapid air vehicle"designed to fly at 20 km (12.4 mi) higher than conventional aircraft and over four times the speed of sound twice the speed of Concorde.
civilian supersonic flight held on by the skin of its teeth. Concorde may have carried the wealthy and glamorous across the Atlantic in under three hours,
and it ended up as a tiny fleet, only flying with British airways and Air france because of French and British government pressure.
According to Airbus, the craft is essentially a flying tanker with most of the fuselage made up of liquid oxygen and ecofriendly liquid hydrogen.
Forward of this is a passenger cabin for 24 people, with the cockpit in the bow.
It's also a very odd looking airplane with a gothic delta wing that gives it a strangely truncated look
and oxygen are burned to keep the aircraft properly trimmed. But what really sets the Airbus dsign apart is its suite of propulsion systems used to keep it aloft.
On a typical flight it would take off like a conventional plane using ordinary turbojet engines, but once in the air, an open door in the stern of the plane reveals a rocket motor.
When this fires, it sends the aircraft into a near vertical trajectory, accelerating it to supersonic speeds.
As the airplane approaches Mach one, the turbojets shut down and retract into the fuselage. On completion of the acceleration phase the plane is now flying at anywhere from Mach 4 to Mach 4. 5 at an altitude of 30,000 to 35,000 m (100,000 to 150
000 ft). The rocket motor shuts down and is concealed again as the aft door slides shut to reduce drag.
A ramjet now kicks in and the aircraft cruises along its flight path and can cover a range of 9, 000 km (5, 600 mi) in three hours the equivalent of Tokyo to Los angeles or Paris to San francisco. Meanwhile,
the wing fuselage design dissipates the sonic shock wave over 110 to 175 km (68 to 109 mi)
and angles it at 11 to 15 degrees so it doesn't reach the ground.
At the end of the journey split flaps reduce speed and the turbojets take over for approach and landing.
Airbus says that the supersonic passenger craft can operate from conventional airports so long as they can supply the cryogenic propellants.
It wouldn't interfere with existing air corridors, would operate in all weather, and only the rocket motor requires special maintenance.
According to its specifications, it could carry two or three tons of cargo, which is equivalent to 24 passengers and luggage.
It's highly unlikely that the Airbus supersonic will ever be built, but if it is,
The company sees it as catering to VIP passengers who need to make round-trip transcontinental trips in a single day.
and preserved for later transportation to Earth, where they will be subjected to scientific analysis. According to NASA,
Metal-oxide nanosheets were arranged on a single plane using a magnetic field. The nanosheets were fixed then in place using a process called light-triggered in-situ vinyl polymerization
like go off-road or climb stairs, they are still often too large and cumbersome for the average wheelchair user.
and allow for the plotting of efficient vehicle and UAV routes. BAE states that the system will be highly versatile and adaptable to a wide range of military assets.
#Self-driving truck hits the highway in world first Daimler Trucks'has shifted gears in its ongoing effort to develop autonomous vehicles.
By fitting its Highway Pilot self-driving system to a Mercedes-benz Actros truck and steering it down a stretch of Autobahn 8 near Stuttgart,
the company has marked the first time an autonomous production semi has been tested out on public roads. Much like the posited advantages of self-driving cars,
Daimler says improvements in driver safety are a compelling reason to pursue the technology in the road freight sector.
Daimler's Highway Pilot system first debuted on the open road last year aboard the Mercedes-benz Future Truck 2025 a concept vehicle intended to demonstrate what a future of autonomous trucking might look like.
Then earlier this year another of the company's concept vehicles, the Freightliner Inspiration, received official licensing to roam the public highways in the state of Nevada.
The latest autonomous expedition saw the Highway Pilot system installed and tested in something other than a concept vehicle for the first time.
and Stuttgart with the Highway Pilot system helping guide the way. The system uses a short-range radar that assess the vehicle's surroundings up to 230 ft (70 m) away in a forward-facing 130-degree arc,
Highway Pilot isn't about letting those behind the wheel plonk their feet on the dashboard and snooze their way to their destination.
Daimler likens the system to the autopilot used in aviation, in that the driver must be prepared to take control at any time.
Daimler had to obtain a special permit from Germany's road traffic regulator, allowing the truck to be driven semi-autonomously on highways at speeds of up to 80 km h (50 mph).
While widespread adoption of autonomous trucks still appears some way off, the opportunity to test out the technology in real-world scenarios will help speed up the process."
"Safe testing in real traffic is absolutely decisive for the development of this technology to market maturity,
So when a researcher airplane made a wrong turn during a thunderstorm and flew straight into a mile-wide cloud,
Dwyer is now chasing down antimatter by releasing weather balloons and planning more head-on flights into storms h
but the designer, who has created also solar bike paths in The netherlands, and glow in the dark roads, had another idea.
He envisioned a mog Free Towerthat would operate using the same air purifying technology hospitals do.
shorter working hours with lower unemployment rates), the built environment (including housing and neighbourhoods renewal, the transport system, etc), consistent culture,
After measuring both the curvature of particle tracks in the detector's magnetic field and the particles'time of flight
or go in preprogrammed routes. The drone is waterproof and small, only weighing 2. 8 lbs.
when touching objects including light taps on the mechanical finger and could be a huge breakthrough for prosthetics, according to its makers.
It has helped GE win jet engine orders worth $100 billion so far from airlines looking to shave their huge fuel bills.
NASA wanted to use them in supersonic aircraft. The U s. military hoped they could be used in a new fighter jet.
but they helped advance the research far enough for GE Aviation division to fund more research and development,
Already, today engines employ elaborate cooling mechanisms that divert air for cooling that otherwise would be used to power the plane.
It is winning about 75 percent of the market for planes that size, and CFM has taken orders for 8, 000 of them worth $100 billion.
The first test flight is expected to take off in the next several weeks. t allowing us to do things we never have been able to do,
who manages the LEAP program for GE Aviation division, of the composite. GE says that by 2020,
and even dropped by helicopter in hard-to-reach disaster zones. It has a solar panel to charge the battery,
The protein acts a bit like a tap to increase or reduce the production of natural compounds depending on how much of the protein is present.
The protein acts a bit like a tap to increase or reduce the production of natural compounds depending on how much of the protein is present.
which the surface of a cellphone put down in a new environment will pick microbiotic stowaways.
essentially, a passenger in the exoskeleton. That, however, was about to change. In the lab of V. Reggie Edgerton, professor of integrative biology and physiology, neurobiology and neurosurgery, Pollock had attached electrical patches to the skin over his spinal cord.
The zinc supplements help with immune function and the transport of water in the body, according to the World health organization.
which are difficult to reach because of the lack of transportation infrastructure, Tidey said.""We know that they've sustained quite a bit of damage,
The 3d printed airway splint, shown here in diagrams of how the device was placed into the patients'lungs.
Pin It The airway splint was designed digitally to fit each of the patients. The three infant boys who were implanted with the new device all had the same life-threatening condition a severe form of a disease called tracheobronchomalacia,
Sixteen-month-old Garrett Peterson's airways"were floppy, with the consistency of a wet noodle,
or holding him could cause Garrett's airways to collapse. This happened repeatedly for months."
"The researchers used CT SCANS of the infants to develop 3d printed airway splints whose length, diameter,
to help keep the infants'weakened airways open. An image made from a CT SCAN of one of the patients.
Pin It Images from a patient CT SCAN were used to generate a 3d model of the patient airway."
the devices kept surrounding tissue from pushing in and sealing the airways shut. The devicessplints are made of a material called, polycaprolactone,
The airway splints were hollow and porous, designed to spread open as the children grew.
The researchers followed the growth of the airways over time with CT and MRI scans.
and expanded to allow the airways to grow in all three patients. All the devices are dissolving as expected
their airways usually grow strong enough to overcome the disorder, and their windpipes eventually will have no signs of the disease that nearly killed them as newborns.
The researchers say the airway splints will dissolve slowly enough to help the infants reach this point.
"He's so happy there's no hint of an issue with his airway splint. He's starting to learn to sit up on his own."
The new 3d design has slashed the transit time between transistor and memory, and the resulting architecture can produce lightning-fast computing speeds up to 1,
target and deter commercial drones could be used to keep the flying robots away from areas where they're not wanted, like government properties, airports or your own backyard.
has ruled that small UAVS cannot be flown within 5 miles of airports and that they must remain below 400 feet (122 meters),
where they are unlikely to interfere with piloted aircraft. But a recent deluge of complaints from pilots
as well as U s. Forest Service employees who have spotted the flying bots near wildfires, has led the FAA to take further action against rule-breaking drone operators.
such as near airports, according to a report by Phys. org. Though the AUDS system doesn't promise to help locate errant drone operators,
so it might be safe to use near airports. The new anti-drone system has been tested in the United kingdom, the United states and France, according to the BBC.
The option to just drop something out of a plane and then totally forget about it hasn't existed, according to DARPA.
and that can also provide navigation information when going on your own for a stroll. The main idea of the device,
and aircraft manufacturing,"said Kim m
#How to save soldiers'lives with fizz One of the biggest challenges for medics on the battlefield is treating blood loss,
The resultant bubbles then act as transport for the clotting agents propelling them deep into a wound as they pop.
Taro Nakajima and colleagues from the RIKEN Center for Emergent Matter Science realized that multiferroic symmetry could also be controlled through a more primitive route.
Raman spectroscopy and transport measurements on the graphene/boron nitride heterostructures reveals high electron mobilities comparable with those observed in similar assemblies based on exfoliated graphene.
the development of new, lighter and stronger materials spanning consumer electronics to aircraft; and faster information searching through large databases e
which cannot result in a net transport of suspended particles. However, the Purdue researchers have overcome this limitation,
increasing the velocity of particle transport by 100 times by applying an alternating current electric field in conjunction with heating the plasmonic nanoantenna using a laser to induce a force far stronger than otherwise possible."
First, the fast transport using alternating current, and then you turn off the electric field and it goes into the plasmonic tweezing mode,
Potential applications already exist for this emerging technology, such as medical imaging, the improvement of navigation systems or even for searches based on images rather than on text.
the team arranged metal-oxide nanosheets into a single plane within a material by using a magnetic field
The nanosheets ended up stuck within the polymer, aligned in a single plane. Due to electrostatic forces, the sheets create electrostatic resistance in one direction but not in the other.
This provides a literal road map for surgeons to follow, showing which tissue is cancerous and
bendable electronics could have many uses, such as monitoring patients'health and keeping tabs on airplanes.
wearable electronics and sensors for monitoring airman health/performance; conformal electronics and antennas for maximizing space efficiency and reducing aerodynamic drag;
Over the last few years, one team of chemists and materials scientists has begun exploring military applications in harsh environments for aircraft, explosive devices and even combatants themselves.
such as an airplane's wing, or even a person's skin. In aircraft applications, Leever explains,
the hybrid flexible system can be used to monitor stresses and strains and report this information through miniature embedded antennas to ground crews or a pilot.
The researchers also are developing the same approach to monitor pilots'health. This involves a biosensor system that can measure heartbeat,
hydration levels, sweat, temperature and other vital signs through miniature circuitry. The system would be embedded on a flexible
wearable patch and would include an antenna to transmit these biometric signals to the pilot or a ground team.
and could detonate the weapon after surviving the initial impact of ground contact after being dropped from aircraft.
the UVM team was able to observe nanoscale defects and boundaries in the crystal grains in the thin films of phthalocyanine--roadblocks in the electron highway."
"Think of these as easy-on ramps onto a highway--instead of an awkward stop sign at the top of a hill--that allow excitons to move far and fast.
This allows organic thin films to carry energy along this molecular highway with relative ease,
a nanoscale integrated optical memory that could open up the route towards ultra-fast data processing and storage.
The results of this new research show, that superconductors may be useful in the process of spin transportation, and ferromagnetics may be used to control spins.
but also in transportation industry power backup, micro grid storage, and for the wider use of renewable energy. OSU officials say they are seeking support for further research
on a multilayered film where the magnetic moments are aligned normal to the plane. They used ion beam irradiation to modify the interface between the dots
and are out on our roads, "said Professor Hermann Kohlstedt and his colleague from Bochum,
Berkeley Lab researchers find a better way to store natural gas as a transportation fuel Researchers with the U s. Department of energy (DOE)' s Lawrence Berkeley National Laboratory (Berkeley Lab) have developed a variety
the widespread use of natural gas as a transportation fuel has been hampered by cumbersome and expensive onboard gas storage tanks and the cost of dispensing compressed natural gas to vehicles.
and sensors that can detect otherwise imperceptible defects in buildings, bridges, and aircraft.""This is the first time anybody has made a flexible chameleon-like skin that can change color simply by flexing it,
or the wings of airplanes.""This is the first time anyone has achieved such a broad range of color on a one-layer, thin and flexible surface,"concluded Change-Hasnain."
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