researchers at University of Michigan Life sciences Institute and University of Texas Southwestern Medical center have discovered. The findings,
Yamashita, a Howard Hughes Medical Institute investigator, Macarthur Fellow and an associate professor at the U-M Medical school, looked through her old image files
but not the other, said collaborator Michael Buszczak, an associate professor of molecular biology at UT Southwestern,
The research, done in the laboratory of Ahmed Zewail, Linus Pauling Professor of Chemistry and professor of physics, will be published in the July 28 print issue of the journal ACS Nano("Transient Structures and Possible Limits of Data
"explains Giovanni Vanacore, a postdoctoral scholar and an author on the study. The speed with which data can be recorded is determined both by the speed of the laserhat is,
one 0 or 1, every nanosecond,"says Jianbo Hu, a postdoctoral scholar and the first author of the paper."
South korean researchers at the Center for Self-assembly and Complexity, Institute for Basic Science (IBS), Department of chemistry and Division of Advanced Materials science at Pohang University, have created a new LIB made from a porous solid
#Visualizing RNAI at work University of Tokyo and Kyoto University researchers have revealed the molecular mechanism of RNA interference (RNAI), the phenomenon by
which the synthesis of a specific protein is inhibited, by real time observation of target RNA cleavage at the single-molecule level.
a research group at the University of Tokyo (Professor Takuya Ueda, Professor Yukihide Tomari, Researcher Chunyan Yao and Research Associate Hiroshi M Sasaki,)
and at Kyoto University (Researcher Hisashi Tadakuma), has developed a single-molecule imaging assay for observing target RNA cleavage by RISC in a test tube in real time for the first time,
doctoral student at the Max Planck Institute in Erlangen and lead author of the study. Vibrations could also be determined similarly,
#'Invisible'protein structure explains the power of enzymes A research group at Ume University in Sweden has managed to capture
"Research on Bioenergy is an active field at Ume University. An important, practical application of the new knowledge can be enzymatic digestion of useful molecules from wooden raw materials,
"One of the strengths of Ume University is the open cooperative climate with low or no barriers between research groups.
The scientists synthesized Nb3site6 crystals in a laboratory at Tulane University (New orleans. They then separated them into two-dimensional layers, taking samples for further analysis by transmission electron microscopy, X-ray crystal analysis and other methods.
and lecturer at the MIPT Section of the Physics and Chemistry of Nanostructures (DMCP). American colleagues confirmed this prediction in related experiments."
#A new approach to develop highly-potent drugs A new study led by University of Kentucky researchers suggests a new approach to develop highly-potent drugs
Guo holds a joint appointment at the UK Markey Cancer Center and in the UK College of Pharmacy."
former Dean of the UK College of Pharmacy and current UK provost. r. Guo's study has identified a new mechanism of efficiently inhibiting biological processes that are critical to the function of the disease-causing organism,
"In a new study, electrical engineers at the University of California, San diego have designed a cloaking device that is both thin
"said Boubacar Kant, a professor in the Department of Electrical and Computer engineering at the UC San diego Jacobs School of engineering and the senior author of the study."
"said Li-Yi Hsu, electrical engineering Ph d. student at UC San diego and the first author of the study,
and his students live in a cotton-soft nano world, where they create clothing that kills bacteria, conducts electricity, wards off malaria, captures harmful gas and weaves transistors into shirts and dresses.
said Hinestroza, associate professor of fiber science, who directs the Textiles Nanotechnology Laboratory at Cornell. In a nanoscale world and that is our world we can control cellulose-based materials one atom at a time.
Taking advantage of cottons irregular topography, Hinestroza and his students added conformal coatings of gold nanoparticles,
Two of Hinestrozas students created a hooded bodysuit embedded with insecticides using metal organic framework molecules,
Other students have used MOFS to create a mask and hood capable of trapping toxic gases in a selective manner.
Antonello Mallamaci of the International school for Advanced Studies (SISSA) in Trieste, who led the recently-published study
"Mallamaci and Cristina Fimiani, a student at SISSA and first author of the article, created synthetic hybrid enzymes."
highlighting the importance of training young researchers. Fimiani was a student at the University of Trieste
when she began this study at SISSA for her dissertation.""The working hypothesis was unorthodox
allowing her to learn lab techniques necessary for all students in this field.""Fimiani was stubborn however,
Fimiani is continuing her studies as a graduate student at SISSA.""All of this took place without specific funding for this research project,
but rather through funds that SISSA invests in training students, "says Mallamaci.""This means that outstanding students like Cristina can take advantage of opportunities here
which can contribute to their academic and professional future
#The influence of surface structure on nanoparticle shape control (Nanowerk News) Peng Zhang, a professor with Dalhousies Department of chemistry,
leads a nanoscience research team of undergraduate and graduate students. Published this week in Nature Communications("The surface structure of silver-coated gold nanocrystals and its influence on shape control"),Zhangs teams report on the discovery of a new methodology to study nanoparticle structures.
Dr. Zhang and his Phd student Daniel Padmos examined gold and silver nanoparticles two very important materials, particularly in the future of biomedicine.
At this size, gold and silver look and behave much differently than they do used when theyre to make rings and necklaces.
Dr. Zhang, Padmos and their collaborators from Northwestern University and University of California, Riverside combined a powerful x-ray from a mile-sized synchrotron facility with computer modelling based on density functional theory.
said Velev, INVISTA Professor of Chemical and Biomolecular engineering at NC State and the papers corresponding author.
It was observed by a team of researchers including Gilles Hickson, an assistant professor at the University of Montreals Department of Pathology and Cell biology and researcher at the CHU Sainte-Justine Research Centre, his assistant Silvana Jananji, in collaboration with Nelio
Rodrigues, a Phd student, and Sergey Lekomtsev, a postdoc, working in the group led by Buzz Baum of the MRC Laboratory for Molecular Cell biology at University college London.
#Nanoscale light-emitting device has big profile University of Wisconsin-Madison engineers have created a nanoscale device that can emit light as powerfully as an object 10,000 times its size.
In a paper published July 10 in the journal Physical Review Letters("Extraordinarily large optical cross section for localized single nanoresonator"),Zongfu Yu, an assistant professor of electrical and computer engineering,
a Ph d. student in Yu's group and lead author of the paper. Much as a very thin string on a guitar can absorb a large amount of acoustic energy from its surroundings
This significant development in the understanding and manipulation of quantum objects is the outcome of a collaboration between Professor Stéphane Kéna-Cohen of Polytechnique Montréal, Professor Stefan Maier and research associate Konstantinos
Daskalakis of Imperial College London. Their work has been published in the prestigious journal Physical Review Letters("Spatial Coherence and Stability in a Disordered Organic Polariton Condensate".
"Microcavity To produce the room-temperature condensate, the team of researchers from Polytechnique and Imperial College first created a device that makes it possible for polaritons-hybrid quasiparticles that are part light
Konstantinos Daskalakis, Imperial College London) Quantum objects visible to the naked eye Quantum mechanics tells us that objects exhibit not only particle-like behaviour,
the team of researchers from Polytechnique and Imperial College first created a device that makes it possible for polaritons-hybrid quasiparticles that are part light
"says Professor Kéna-Cohen.""Our work demonstrates that it is possible to obtain comparable quantum behaviour using'impure'and disordered materials such as organic molecules.
Fertile ground for studying fundamental questions According to Professor Maier, this research is also creating a platform to facilitate the study of fundamental questions in quantum mechanics."
Professor Kéna-Cohen concludes:""One fascinating aspect, for example, is the extraordinary transition between the state of non-condensed particles and the formation of a condensate.
University of Oxford) Graphene promises to be a'wonder material'for building new technologies because of its combination of strength, flexibility, electrical properties,
'said Professor Nicole Grobert of Oxford university's Department of Materials, who led the research.''Because it is allowed to grow naturally in single graphene crystals there are none of the grain boundaries that can adversely affect the mechanical and electrical properties of the material.'
a DPHIL student at Oxford university's Department of Materials, said:''Using widely-available polycrystalline metals in this way can open up many possibilities for cost-reduction
'said Professor Grobert.''Of course a great deal more work is required before we get graphene technology, but we're now on the cusp of seeing this material make the leap from the laboratory to a manufacturing setting,
This invention adds to the growing patent portfolio of nanomaterials and their production technologies from Professor Nicole Grobert's Nanomaterials By design Group.
Under a commercialisation programme devised by Isis Innovation, the technology commercialisation company of the University of Oxford,
Professor Grobert also plans to manufacture and sell her range of specialty nanomaterials as part of a new business venture e
graduate students working in the lab of Charles Lieber, the Mark Hyman Jr. Professor of Chemistry, takes advantage of two long-understood principles.
One is Plateau-Rayleigh instability, an aspect of fluid dynamics that describes why a thin stream of water breaks up into smaller droplets.
graduate students working in the lab of Charles Lieber, the Mark Hyman Jr. Professor of Chemistry, could have applications in areas ranging from consumer electronics to solar panels.
This is really a fundamental Discovery day said. Were still in the early stages, but we think there is a lot of room for discovery, both of fundamental properties of these structures as well as applications.
A new technology--called"Sticky-flares"--developed by nanomedicine experts at Northwestern University offers the first real-time method to track
"Mirkin is the George B. Rathmann Professor of Chemistry in the Weinberg College of Arts and Sciences and professor of medicine, chemical and biological engineering, biomedical engineering and materials science and engineering.
Aurasense, Inc.,a biotechnology company that licensed the Nanoflare technology from Northwestern University, and EMD-Millipore, another biotech company, have commercialized Nanoflares.
Now researchers from Korea University in Seoul, have developed an easy and microelectronics-compatible method to grow graphene
J. Kim/Korea University, Korea)" For integrating graphene into advanced silicon microelectronics, large-area graphene free of wrinkles, tears and residues must be deposited on silicon wafers at low temperatures,
"said Jihyun Kim, the team leader and a professor in the Department of Chemical and Biological engineering at Korea University."
a researcher from University of Malaya who lead the project. Then, they wrapped the Ag/Tio2 nanoparticles in sheets of reduced graphene oxide (RGO), a thin layer of carbon atoms arranged in a honeycomb pattern.
"researchers from MIT and the Federal University of Goiás in Brazil demonstrate a novel method for using nanoparticles
Ferdinand Brandl and Nicolas Bertrand, the two lead authors, are former postdocs in the laboratory of Robert Langer, the David H. Koch Institute Professor at MIT Koch Institute
Eliana Martins Lima, of the Federal University of Goiás, is the other co-author. Both Brandl and Bertrand are trained as pharmacists,
says Frank Gu, an assistant professor of chemical engineering at the University of Waterloo in Canada, and an expert in nanoengineering for health care and medical applications. hen you think about field deployment,
Experts at The University of Nottingham have discovered the first fully synthetic substrate with potential to grow billions of stem cells.
Professor of Biomedical Surfaces in the School of Pharmacy and Chris Denning, Professor of Stem Cell biology in the School of medicine and funded by the Engineering and Physical sciences Research Council (EPSRC).
Professor Alexander, Director of the Interface and Surface Analysis Centre, and his team have been searching for polymers on
Professor Alexander said: he possibilities for regenerative medicine are still being researched in the form of clinical trials.
Professor Denning, whose field is in cardiac stem cell research, said: he field of regenerative medicine has snowballed in the last five years
A research team led by Professor Kazunori Kataoka, Department of Bioengineering, School of engineering, The University of Tokyo (concurrently serving as the Director of the Innovation Center of Nanomedicine,
Kawasaki Institute of Industry Promotion), and Professor Nobuhiro Nishiyama, Chemical Resources Laboratory, Tokyo Institute of technology, has developed successfully a nano crystal aggregate (nanomachine) technology to deliver a gadolinium complex (Gd-DTPA
or magnevist) broadly used as an MRI contrast agent to the affected area("Hybrid Calcium phosphate-Polymeric Micelles Incorporating Gadolinium Chelates for Imaging-Guided Gadolinium Neutron capture Tumor Therapy").
The research team has clarified that selective accumulation of the developed nanomachine in a cancer tumor enables contrast imaging of a solid cancer.
"The study was led by researchers at Karolinska Institutet who collaborated with a group at Finland's Aalto University.
says Professor Pekka Orponen, who directed the team at the Aalto University Computer science department. The possible applications are many.
The team at Karolinska Institutet has made previously a DNA nano-caliper used for studying cell signalling.
"said Maiken Mikkelsen, an assistant professor of electrical and computer engineering and physics at Duke.""We can now start to think about making fast-switching devices based on this research,
ISEM Phd student Monirul Islam said. ut the biggest challenge is to charge storage in a small volume as well as being able to deliver that charge quickly on demand.
a team of Phd students, led by Dr Konstantin Konstantinov under the patronage of ISEM Director Professor Shi Xue Dou and with the support of Professor Hua Kun Liu,
Dr Konstantinov said. f we could efficiently separate the layers of carbon we could then use both surfaces of each layer for charge accumulation.
Phd student Monirul Islam said. etting the proportions or ratios of the components appropriately in order to obtain a composite material with maximum energy storage performance was another challenge.
"explained Andrei Fedorov, a professor in the George W. Woodruff School of Mechanical engineering at Georgia Tech."
"The researchers-who included graduate students James Silva, Drew Loney and Ren Geryak and senior research engineer Peter Kottke-tried the experiment again using glycerol,
In a seminal paper in the scientific journal Nature Photonics("All-plasmonic Mach-Zehnder modulator enabling optical high-speed communication at the microscale"),Juerg Leuthold, professor of photonics and communications
The plasmon-trick For this sleight of hand the researchers led by Leuthold and his doctoral student Christian Haffner
"as the ETH professor puts it in a nutshell. At present the reliability of the modulator is being tested in long term trials,
along with graduate student Yanyan Wang at Texas A&m University (USA) has provided a solution. For the first time the researchers have been able to produce amphiphilic polycarbonate block copolymers in
also a gastroenterologist at MGH and an instructor at Harvard Medical school. A material like this represents a real advance
Traverso and Robert Langer, the David H. Koch Institute Professor at MIT and a member of the Koch Institute, are the senior authors of a paper in the July 27 issue of Nature Materials("A ph
a professor of medical science and engineering at Brown University who was not involved with this study.
Chang Lu, a professor of chemical engineering at Virginia Tech, has worked on the development of tools to effectively analyze living cells with the long-term goal of gaining a better understanding of a range of diseases.
In his lab, Lu and his students develop small microfluidic devices with micrometer features for examining molecular events inside cells.
The latest breakthrough comes from Lu's collaboration with Kai Tan at the University of Iowa, a systems biologist and associate professor of internal medicine.
#Researchers design first artificial ribosome Researchers at the University of Illinois at Chicago and Northwestern University have engineered a tethered ribosome that works nearly as well as the authentic cellular component,
or organelle, that produces all the proteins and enzymes within the cell. The engineered ribosome may enable the production of new drugs and next-generation biomaterials and lead to a better understanding of how ribosomes function.
The artificial ribosome, called Ribo-T, was created in the laboratories of Alexander Mankin, director of the UIC College of Pharmacy Center for Biomolecular Sciences,
assistant professor of chemical and biological engineering. The human-made ribosome may be able to be manipulated in the laboratory to do things natural ribosomes cannot do.
Researchers at Purdue University have shown how an optical material made of aluminum-doped zinc oxide (AZO) is able to modulate
"said doctoral student Nathaniel Kinsey.""Otherwise, your material would heat up and melt when you start pushing it really fast.
working with a team of researchers led by Alexandra Boltasseva, an associate professor of electrical and computer engineering,
and Vladimir M. Shalaev, scientific director of nanophotonics at Purdue's Birck Nanotechnology Center and a distinguished professor of electrical and computer engineering."
The Optica paper, featured on the cover of the journal, was authored by Kinsey, graduate students Clayton Devault and Jongbum Kim;
visiting scholar Marcello Ferrera from Heriot-Watt University in Edinburgh, Scotland; Shalaev and Boltasseva. Exposing the material to a pulsing laser light causes electrons to move from one energy level called the valence band to a higher energy level called the conduction band.
the W. M. Keck Professor of Energy at MIT and a senior author of a paper describing the findings in the Journal of Physical chemistry C("Reactivity of Perovskites with Water:
an associate professor of mechanical engineering, that determination can now be used to predict a materials suitability as a catalyst.
explains Kelsey Stoerzinger, an MIT graduate student and the papers lead author. While most attempts to study such surface science use instruments requiring a vacuum
"says study first author Narayanan"Bobby"Kasthuri, of the Boston University School of medicine.""We had this clean idea of how there's a really nice order to how neurons connect with each other,
"said Manish Kumar, assistant professor of chemical engineering, Penn State.""They have functions that are hard to replicate in synthetic systems."
"said Patricia Dove, a University Distinguished Professor at Virginia Tech and the C. P. Miles Professor of Science in the College of Science."
and build everything, says Kar, an assistant professor of physics in the College of Science. We were on a journey,
adds Sridhar, the Arts and Sciences Distinguished Professor of Physics and director of Northeasterns Electronic Materials Research Institute.
and graduate students, contributors included researchers in government, industry, and academia from the United states, Mexico, and India.
and the connection to community support,"adds Dr. Lori Feldman-Winter, a professor of pediatrics at Cooper University Hospital in New jersey,
Researchers from the University of Kansas found that high doses of intravenously supplied Vitamin c effectively eradicates cancer cells in human subjects.
Researchers at the University of Virginia School of medicine have discovered recently that lymphatic vessels do in fact go up into the brain,
"In Alzheimer's, there are accumulations of big protein chunks in the brain. We think they may be accumulating in the brain
Daniel Altman, senior economic editor at Foreign policy magazine and an adjunct professor at New york University's Stern School of business, called the bailouts"stupid"in a recent column."
but how much practical use it will be is less clear, notes Guy Cox, a microscopy specialist at the University of Sydney,
Scientists working at the University of Rostock in Germany proposed a similar idea in the early 1990s,
Today in Nature, a team led by Kim Lewis of Northeastern University in Boston, Massachusetts, report that the antibiotic,
says Gerard Wright, a biochemist at Mcmaster University in Hamilton, Canada, who was not involved with the study. obody knew
But medical microbiologist Timothy Walsh of Cardiff University, UK, urges caution because the drug has been tested against only a small number of lab strains.
#Phd students build brain-controlled FPV drone Two Phd students from University of Florida, Marvin Andujar and Chris Crawford, have built a mind-machine method to control a drone through a wearable electroencephalographic (EEG) Brain-Computer Interface device.
The Division of Multimedia Properties at University of Florid f
#Jaguar land rover Mind Sense research monitors brainwaves through the hands via sensors in the steering wheel Jaguar land rover has revealed the ixth Senseproject,
However, instead of simply thinking about the actions and movements, the training involves associating a specific mental image with each command.
the clinical trial was led by principal investigator Richard Andersen, the James G. Boswell Professor of Neuroscience at Caltech, neurosurgeon Charles Y. Liu, professor of neurological surgery, neurology,
and he since has been training with Caltech researchers and staff at Rancho Los Amigos to control a computer cursor
associate professor of neurology at USC and co-director of the USC Neurorestoration Center. hese very important early clinical trials could provide hope for patients with all sorts of neurologic problems
The Rehabilitation Sixteen days after his implant surgery, Sorto began his training sessions at Rancho Los Amigos National Rehabilitation Center,
also a clinical professor of neurology at the Keck School of medicine of USC. his research is relevant to the role of robotics and brain-machine interfaces as assistive devices,
He says the study has inspired him to continue his education and pursue a master degree in social work. his study has been very meaningful to
researchers at the University of Virginia School of medicine have determined that the brain is connected directly to the immune system by vessels previously thought not to exist.
said Jonathan Kipnis, Phd, professor in the UVA Department of Neuroscience and director of UVA Center for Brain Immunology and Glia (BIG).
Harris, a Phd, is an assistant professor of neuroscience and a member of the BIG center.
there are accumulations of big protein chunks in the brain, Kipnis said. e think they may be accumulating in the brain
An international team of scientists led by Cardiff University researchers has provided the strongest evidence yet of
The breakthrough builds on two landmark studies led by members of the Cardiff University team, published last year in the journal Nature. ee finally starting to understand what goes wrong in schizophrenia,
says lead author Dr Andrew Pocklington from Cardiff University MRC Centre for Neuropsychiatric Genetics and Genomics. ur study marks a significant step towards understanding the biology underpinning schizophrenia,
Professor Hugh Perry, who chairs the Medical Research Council Neuroscience and Mental health Board said: his work builds on our understanding of the genetic causes of schizophrenia unravelling how a combination of genetic faults can disrupt the chemical balance of the brain. cientists in the UK,
based at Cardiff University MRC Centre for Neuropsychiatric Genetics and Genomics. This paper not only confirms their previous findings,
Sientists at the Keck School of medicine of USC have discovered that a protein known as PICALM regulates removal of toxic plaques from the brain,
characterized by the loss of memory and other mental abilities linked to an accumulation of amyloid-beta and other toxic compounds in the brain.
director of the Zilkha Neurogenetic Institute and holder of the Mary Hayley and Selim Zilkha chair for Alzheimer Disease research at the Keck School of medicine. ur new study shows that a deficiency in PICALM in blood vessels
leading to its accumulation and cognitive impairment. This new study provides fundamental new information about PICALM
the group found that low levels of PICALM in brain endothelial cells lead to amyloid-beta accumulation in the brain.
#DNA Breakage Underlies Learning and Age Related Neurodegeneration The process that allows our brains to learn
creating damage that the neurons must immediately repair, according to Li-Huei Tsai, the Picower Professor of Neuroscience and director of the Picower Institute for Learning and Memory at MIT.
This process is essential to learning and memory. ells physiologically break their DNA to allow certain important genes to be expressed,
which ultimately pave the way for the transcriptional program that supports learning and memory, and many other behaviors.
and particularly with some genetic conditions, the efficiency of the DNA repair system is compromised, leading to the accumulation of damage,
Previous research has shown that the expression of genes involved in learning and memory is reduced as people age.
a professor of genetics and neurology at Harvard Medical school who was involved not in the research. he work elegantly links DNA strand break formation by the enzyme topoisomerase IIß to the temporal control of transcription,
#Reprogramming of DNA Obeserved in Human Germ cells for First time A team of researchers led by the University of Cambridge has described for the first time in humans how the epigenome the suite of molecules attached to our DNA that switch our genes on and off is erased comprehensively in early primordial germ cells prior to the generation of egg
A team of researchers led by the University of Cambridge has described for the first time in humans how the epigenome the suite of molecules attached to our DNA that switch our genes on
Professor Azim Surani from the Wellcome Trust/Cancer Research UK Gurdon Institute at the University of Cambridge, explains:
Within the blastocyst, some cells are reset to their master state becoming stem cells, which have the potential to develop into any type of cell within the body.
Professor Surani and colleagues showed that a process of reprogramming the epigenetic information contained in these primordial germ cells is initiated around two weeks into the embryo development
Walfred Tang, a Phd student who is the first author on the study, adds: ur study has given us a good resource of potential candidates of regions of the genome where epigenetic information is passed down not just to the next generation but potentially to future generations, too.
says Professor Surani. In fact, the researchers found that a notable fraction of the retroelements in our genome are scapeesand retain their methylation patterns particularly those retroelements that have entered our genome in our more recent evolutionary history.
Craig Brierley University of Cambridgeimage Credit: The image is credited to the researchers/Celloriginal Research: Full open access research for Unique Gene Regulatory Network Resets the Human Germline Epigenome for Developmentby Walfred W c. Tang, Sabine Dietmann, Naoko Irie, Harry
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