In collaboration with Pr Véronique Del Marmol (Department of Dermatology, Erasme Hospital, ULB) and the group of Pr François Fuks (Laboratory of cancer epigenetics, Faculty of medicine, ULB), Larsimont and colleagues demonstrated that
M d.,lead author of the study and director of the clinical retina research unit At wills Eye Hospital."
#First hospital light fixture to kill bacteria safely, continuously becomes commercially available in North america Indigo-Clean#is a light fixture manufactured through an exclusive licensing agreement with the University of Strathclyde in Glasgow, Scotland,
a large teaching hospital operated by NHS (National Health service) Greater Glasgow and Clyde. The technology and its effectiveness have been the subject of more than 20 peer-reviewed academic publications and 30 conference presentations since 2008.
"The Centers for Disease Control and Prevention (CDC) reports around 1 in 25 hospital patients in the US have at least one infection contracted in the health care setting.
and 99,000 deaths in acute care hospitals in the U s. and add $35-45 billion in excess health care costs each year.
HAIS can also result in significant financial penalties for hospitals under the Affordable Care Act.
those providers scoring poorly in the Hospital-Acquired Condition (HAC) program receive lower Medicare reimbursements.
With this knowledge, researchers can now test ER-stress blocking drugs in the clinic, and carry out fundamental research on how different types of pain grouped under the name"neuropathic"differ from each other
"says Dr. Kim who is also Professor of Surgery at Case Western Reserve University School of medicine and the Charles Hubay Chair at UH Case Medical center."
The new Phase I clinical trial is being supported by University Hospitals as well as a significant philanthropic effort including the Immunogene Therapy Fund, Paula and Ronald Raymond Fund and the Kathryn and Paula Miller Family Fund."
#Bonelike 3-D silicon synthesized for potential use with medical devices"Using bone formation as a guide,
researchers at Boston Children's Hospital and Harvard Medical school have restored hearing in mice with a genetic form of deafness.
a specialist in genetic hearing loss at Boston Children's Hospital who is familiar with the work."
as well as Tang Du Hospital in China, University of the Negevin, Israel, and the Instituto Neurologico C. Besta in Italy.
Cory Abate-Shen (Columbia University), Nima Sharifi (Cleveland Clinic) and Jeffrey Karnes (Mayo Clinic), and contributions from Genomedx.
"We are enthusiastic about the next step of clinical assessment for testing DNA-PKCS inhibitors in the clinic.
Oliver Eickelberg, Chairman of the Comprehensive Pneumology Center (CPC) at the Helmholtz Zentrum München and University Hospital of the Ludwig-Maximilians-Universität
The protection allowed the researchers to safely give a dose 16 times higher than they could with the formulation now used in cancer clinics,
Mason Freeman, Massachusetts General Hospital; David Bushinsky, University of Rochester; and Martha Mayo, Dahlia Garza, Yuri Stasiv, Rezi Zawadzki and Lance Berman, from Relypsa a
including investigators from the University of Mississippi Medical center (UMMC), has identified a gene that underlies healthy information processing--a first step on a complicated road to understand cognitive aging and age-related diseases, such as Alzheimer's disease.
"said Dr. Carla Ibrahim-Verbaas, a resident in neurology at Erasmus University Medical center in Rotterdam, The netherlands,
""The hope for a definitive cure and an effective vaccine has been frustrated by HIV's endless propensity to subvert the host's defences
"says Dr. Markus Selzner, a transplant surgeon in the Multi-Organ transplant Program at TGH, co-investigator of the clinical trial and the transplant surgeon who performed the donor operation.
The medical device encloses the liver in a sterile environment, circulating oxygenated blood and nutrients into the liver at body temperature, allowing it to improve
"says Dr. David Grant, Surgical Director of the Multi-Organ transplant Program, co-investigator of the clinical trial who also transplanted the donor liver,
which had been placed on the medical device, into the recipient.""This new technology can help us answer critical questions such as,
and how public health officials are working with those groups. Since the 1990s about half of women with HIV delivering babies in Canada were born foreign.
"said Joel Singer, professor in the School of Population and Public health at UBC, who is presenting at IAS 2015."
"The researchers say this recent success stems largely from public health initiatives to ensure women in these high-risk populations are tested
and infants is to engage hard-to-reach populations in health care and allow them to access prenatal care,
It will only be available in the Ebola Treatment Units, not the hospitals,"Sakoba Keita,
More than half of South korea's infections have been traced to a hospital in Pyeongtaek city, 65 km (40 miles) southwest of Seoul, where the man shared a room with another patient."
Officials have not identified the hospitals where MERS patients are being treated, but the Pyeongtaek facility has been shut
His visit to us was just unavoidable exposure to other people in the hospital,"the nurse,
When the man was admitted at another hospital, where he was diagnosed finally, he at first only told staff he had visited Bahrain,
"said an official at the hospital where he was diagnosed on May 20, who also declined to be identified."
He is in hospital in China. As of Wednesday, the index patient was on a respirator in a government-designated hospital.
The fund will also bring in mentors from Manipal Hospitals, Narayana Health, and Pfizer. he devices could become the new standard of care for breast screening in India and other low-resource markets around the world.
and commercialized innovative medical devices like Notouch Breastscan and Infrascan. He co-founded UE Lifesciences in 2009 to develop innovative yet cost
fatigue or even tremors after a long day at the hospital can make things challenging,
is currently being tested at Sickkids Hospital, and researchers are hoping that the technology might soon lend a helping hand to surgeons around the country.
from the Children Hospital of Los angeles (CHLA) took a step forward and ordered a fully-3d model of his patient heart. s useful as scans are for visualizing structural defects,
currently performed at only a handful of pediatric hospitals in the US. Studying the heart model allowed Kim to accurately plan the procedure
associate professor of biomedical engineering at Columbia Engineering and of radiology at Columbia University Medical center (CUMC), has developed a new microscope that can image living things in 3d at very high speeds.
Blood transfusions can sometimes prevent such attacks but there are currently no good ways to predict when a vaso-occlusive crisis which can last for several days is imminent. ou don know exactly
the researchers were able to preserve all aspects of reproductive health in post-stress mice, thus suggesting a single molecular target that could help alleviate a range of stress-induced fertility problems. t is possible that manipulation of RFRP3 signaling in humans may relieve stress-related reproductive dysfunction,
#Smart devices track hand-washing in hospitals to help reduce the spread of infection In fact,
Administrators usually just spend a few days a month monitoring health care workers, noting hand-hygiene habits on a WHO checklist.
and Philip Liang SM 6 is using smart devices to monitor hand hygiene among hospital staff
A 2014 study in the Journal of Infection and Public health concluded that compliance with WHO hand-washing rules jumped 25 percent in one month when staff used Medsense in a 16-bed hospital unit at Salmaniya
Currently, the Royal Brompton and Harefield hospital in London is studying the correlation between the Medsense system and reduction in HAIS.
wee trying to be a support system for the hospital. In the atient zone Medsense consists of four smart devices,
and can collect data around the clock. leanstart General Sensing may tackle a serious health care issue, but its core technology started as a novelty item:
When a researcher requested the technology to monitor health care staff, however, the startup decided to get a clean start in the health care industry,
hich they say is recession-proof, Gips says. And after learning about WHO hand-hygiene guidelines, the team developed Medsense as an automated way to help administrators monitor hand-washing among staff.
In 2011, researchers at Queen Mary Hospital in Hong kong published a paper in the journal Biomed Infectious disease that found Medsense was 88 percent accurate in monitoring staff compliance with THE WHO guidelines.
and Medsense has been trialed in 10 hospitals across the United states and Europe, and in Saudi arabia, Bahrain, and Qatar.
as the wearers move through the atient journeythe waiting room, pre-procedure, procedure, and recovery room. General Sensing creates digital floor maps of an area being studied;
Another possible application is real-time location of surplus staff particularly important when there a sudden influx of patients in one area of a hospital,
as well as public health in the case of diseases that can move from animals to humans, the paper authors wrote.
the multidisciplinary team also included Michel Gilliet of Switzerland Lausanne University Hospital, and Jure Dobnikar and Daan Frenkel of the University of Cambridge.
Researchers at Case Western Reserve and UT Southwestern Medical center this week announced that they have taken significant steps toward turning this once-improbable idea into a vivid reality.
the Ingalls Professor of Cancer Genetics at the university School of medicine and a medical oncologist at University Hospitals Case Medical center Seidman Cancer Center. e have developed a drug that acts like a vitamin for tissue stem cells,
from the Harrington Discovery Institute at University Hospitals, and from multiple National institutes of health grants that included the Case GI SPORE,
and the National Center for Accelerating Innovation at the Cleveland Clinic. Additional support was received from the Marguerite Wilson Foundation;
This device would be a great leap forward in cheap medical devices for underdeveloped countries, where simple medical care,
if a tissue is cancerous, according to researchers from the Department of energy Oak ridge National Laboratory and Brigham and Women Hospital/Harvard Medical school.
#Scientists successfully test immunogen a component for potential HIV vaccine Team of researchers from The Scripps Research Institute, INTERNATIONAL AIDS Vaccine Initiative and The Rockefeller University have shown successfully that an experimental vaccine candidate
In fact, scientists believe that findings of the study could provide key information for the development of an effective AIDS vaccine.
may become one of the parts of first successful HIV vaccine. Image credit: scripps. eduefforts to create effective vaccine against HIV so far have been virtually fruitless.
However, scientists already describe results of this latest research as spectacular. The long-term goal of the research is to develop a vaccine that prompts the body to produce antibodies that bind to HIV
and prevent infection and current experiments with mice models showed promising results. Many vaccines for other diseases use a dead
or inactive version of the disease-causing microbe itself to trigger antibody production. However, this simple approach does not work with HIV immunizations with ativehiv proteins are ineffective in triggering an effective immune response
This makes HIV vaccine a particularly challenging task for scientists, which explains why science still has produced not an effective one.
This challenge did not make scientists believe that AIDS vaccine is impossible. Instead they figured out that it has to consist of a series of related,
Professor David Nemazee evaluated results like that he vaccine appears to work well in our mouse model to rimethe antibody response In another research scientists used the same immunogen in a slightly different mouse model,
which showed promising results As well as scientists have taken approach to collect a variety of different immunogens to develop a united HIV vaccine,
HIV vaccine would be a major breakthrough at fight against AIDS, as it still is arguably the biggest threat to human population.
vaccine could be one of the greatest scientific achievements of the century. Source: Scripp s
#Researchers develop a new means of killing harmful bacteria The global rise in antibiotic resistance is a growing threat to public health,
MA#A new study led by researchers at Harvard T. H. Chan School of Public health finds that a malaria parasite protein called calcineurin is essential for parasite invasion into red blood cells.
Long before those uses reach the clinic, however, gene editing will be used to probe the role of genes,
#Pioneering gene therapy takes aim at inherited blindness Canada first human gene therapy trial for eyeshe replacement of a faulty gene with a healthy ones now underway at the Royal Alexandra Hospital to preserve
Currently, there are no vaccines or treatments specifically for Marburg infections. The findings were published online ahead of print today in the journal Plos Pathogens.
The high cost of creating independent vaccines or treatments for each of the different viruses in this family necessitates intelligent design of immunogens (antibody-inducing molecules).
such as in hospitals, in manufacturing facilities and in airplane cabins. Visible light communications has the potential to significantly increase the speed of Internet connection in multiuser indoor environments due to the broad bandwidth of the visible light,
said Annabi. e see great potential for use in the clinic. Our method is simple,
said Dr. James K. Min, director of the Dalio Institute of Cardiovascular Imaging at Newyork-Presbyterian Hospital/Weill Cornell Medical center,
In collaboration with researchers from Emory University School of medicine in Atlanta and Cedars-Sinai Medical center in Los angeles, the researchers reviewed medical records of 9, 715 patients in the area surrounding Nashville, Tennessee,
who were referred by their primary care physicians to a single outpatient clinic from 1996 to 1999.
the investigators tracked the status of all participants through the National Death Index, a central computerized index from the National Center for Health statistics.
where the local health care infrastructure might not be able to support the level of research
#Bonelike 3-D silicon synthesized for potential use with medical devices Semiconducting silicon spicules engage tissue like a bee stinger.
Researchers have developed a new approach for better integrating medical devices with biological systems. The researchers, led by Bozhi Tian,
researchers at Boston Children Hospital and Harvard Medical school have restored hearing in mice with a genetic form of deafness.
a specialist in genetic hearing loss at Boston Children Hospital who is familiar with the work. ochlear implants are great,
#HIV vaccine: Pushing the Envelope A new study led by scientists at Harvard Medical school and Beth Israel Deaconess Medical center demonstrates that a heterologous prime-boost HIV-1 vaccine regimen protected 50 percent of vaccinated nonhuman primates against challenges with the simian immunodeficiency virus (SIV),
a virus similar to HIV that infects nonhuman primates. Published in the July 2 online edition of Science, these new findings provide a new strategy for the clinical development of this novel HIV-1 vaccine candidate. espite the urgent need for a safe and effective
global HIV-1 vaccine, only four vaccine concepts have been evaluated for protective efficacy in humans over the past 30 years,
said lead author Dan Barouch, HMS professor of medicine and director of the Center for Virology and Vaccine Research at Beth Israel Deaconess. e are encouraged very by the results of this latest preclinical HIV-1 vaccine study
and believe the findings may lead to a clear path forward for evaluating this HIV vaccine candidate in humans.
In this work, nonhuman primates were given first a dose of adenovirus serotype 26 vectored vaccine to rimethe immune system to mount an antibody response
and then received a oostwith a purified HIV envelope protein (the surface protein of HIV),
which enhances the immune system over time. Adenovirus 26 is responsible for the common cold and is engineered to serve as a carrier,
The study results showed that the prime-boost vaccine regimen provided complete protection in half of the vaccinated nonhuman primates against a series of six repeated challenges with SIV. ur previous studies
of viral vector-based HIV-1 vaccine candidates showed much lower levels of protection against SIV,
Based on these preclinical data, the HIV-1 version of this vaccine regimen is now being evaluated in an ongoing international clinical study sponsored by Crucell Holland BV
the definitive solution to this epidemic will likely be said a vaccine Barouch. hese new findings represent an important step forward. s
#Could dissolvable microneedles replace injected vaccines? The microneedle patch can dissolve in the skin, delivering the flu vaccine painlessly.
New vaccine patch protects against flu in humansflu vaccines delivered using microneedles that dissolve in the skin can protect people against infection even better than the standard needle-delivered vaccine,
according to new research published in Biomaterials. The authors of the study, from Osaka University in Japan, say their dissolvable patch the only vaccination system of its kind could make vaccination easier, safer and less painful.
According to the World health organization, immunization prevents an estimated 2-3 million deaths every year. The continued threat of pandemics such as H1n1 swine flu and emerging infectious diseases such as Ebola makes vaccine development and mass vaccination a priority for global healthcare.
Most vaccines are injected under the skin or into the muscle using needles. While this is an effective delivery method,
it requires medical personnel with technical skills and brings the risk of needle-related diseases and injuries.
where healthcare resources are limited. ur novel transcutaneous vaccination using a dissolving microneedle patch is the only application vaccination system that is readily adaptable for widespread practical use,
we believe it will be particularly effective in supporting vaccination in developing countries. he new microneedle patch Microhyala is dissolvable in water.
taking the vaccine with them. The researchers compared the new system to traditional needle delivery by vaccinating two groups of people against three strains of influenza:
A/H1n1, A/H3n2 and B. None of the subjects had a bad reaction to the vaccine,
people given the vaccine using the microneedles had an immune reaction that was equal to or stronger than those given the vaccine by injection. e were excited to see that our new microneedle patch is
just as effective as the needle-delivered flu vaccines, and in some cases even more effective, said Professor Nakagawa.
Previous research has evaluated the use of microneedles made of silicon or metal, but they were shown not to be safe.
we think it could bring about a major change in the way we administer vaccines globally, said Professor Nakagawa.
and an effective vaccine has been frustrated by HIV endless propensity to subvert the host defences and persist in small populations of long-lasting reservoirs despite antiretroviral therapy,
New knowledge should also help with using adenoviruses in vaccination and gene therapy e
#Scientists discover first NA ambulanceu of T researchers have discovered how severely damaged DNA is transported within a cell
Mekhail team also found that the DNA hospital, also known as the nuclear pore complex, repairs damaged DNA inaccurately.
#New material opens possibilities for super-long-acting pills Medical devices designed to reside in the stomach have a variety of applications,
Now, researchers at MIT Koch Institute for Integrative Cancer Research and Massachusetts General Hospital (MGH) have created a polymer gel that overcomes this safety concern
will enter the clinic in the future. here actually well-trodden ground putting modified T cells into patients.
and deliver drugs and vaccines, a olar spongethat can capture and release carbon dioxide emissions andplastic material that gets better with age.
Oren Shibolet, Head of the Liver Unit at the Tel-aviv Sourasky Medical center, who was involved not in this study. he method provides access to unlimited amounts of functional liver cells
Further, researchers from the team of Jean-Pierre Bourquin from the University Children Hospital in Zürich
using both tests to assess 106 suspected Ebola patients at two clinics in Sierra leone as well as 284 previously collected blood samples.
an infectious disease doctor at Boston Children Hospital, told Science. t was more sensitive than I expected for a rapid antigen diagnostic test. his test can be done in very austere environments,
from the group of Miguel Nicolelis at the Duke university Medical center in Durham, North carolina. In the first, the researchers used electrodes to link the brains of three monkeys to a computer
who developed the technique working with the company Cinogy and the Department of Dermatology, Venereology and Allergology at the University Medical centre Göttingen.
and the simplicity of its use could make it suitable for first aid at home. anticipate that in the future,
#Synchrotron shines a light on future medical devices According to the international team, this technique could be important in the development of devices that are highly sensitive to magnetic fields,
Ray Flynn, 80, had the Argus II device implanted during a four-hour procedure carried out by Prof Paulo Stanga at Manchester Royal Eye Hospital.
and Women Hospital showed that Americans worry that insurance companies and employers may discriminate against them based on their family histories or genetic test results.
If clinics could tell patients whether they should save their money or go directly to high-cost interventions,
fertility clinics could also look to see if these 648 RNA elements are present in the semen."
#World's first malaria vaccine gets green light from European regulatory agency The world's first malaria vaccine has cleared its last major hurdle on its way to being approved for real-world use.
The European Medicines Agency (EMA) the regulatory group in the European union which roughly parallels the FDA gave a positive opinion of the vaccine,
The vaccine RTS S, also called Mosquirix, is the product of British pharmaceutical company Glaxosmithkline and is funded partly by the Bill and Melinda Gates Foundation.
It's not the only vaccine developed to fight malaria; an experimental malaria vaccine called Pfspz was found to be much more effective at preventing malaria infection.
Yet Mosquirix is the first to make it this far along in the approval process. Mosquirix helps to prevent infection from the Plasmodium falciparum, one of the deadlier malaria parasites.
The vaccine prompts the body to produce a higher amount of antibodies to stop the parasite from infecting the liver.
Early results of a clinical trial of Mosquirix showed that three doses of the vaccine could cut the risk of infection in half for children between between five and 17 months old.
and somewhat ineffective vaccine may outweigh the benefits. Still, Africa is need in desperate for a malaria vaccine,
even if it's only partially effective. Malaria infection spread through the blood by mosquito bites kills upwards of 500
"This vaccine could mean children will have only two bouts of malaria a year instead of five,"Dr. Martin De Smet,
#Ebola vaccine is 100 percent effective in Guinea trial, WHO reports A vaccine is"highly effective"against Ebola, according to the World health organization.
Early results from a trial in Guinea show that the drug protected 100 percent of the people who received it against Ebola.
the vaccine could help end the outbreak in West Africa.""The initial results are exciting and very promising,
and the hunt for a vaccine continues. Now, it seems that scientists have a real contender on their hands.
4, 000 people with close ties to Ebola patients either received the vaccine immediately or three weeks after the identification of an Ebola patient in their social circle.
no cases of Ebola were reported, starting 10 days after the initial vaccination, which is needed the time period to develop immunity.
There were 16 cases of Ebola in the group that were given the vaccine three weeks later, however."
Starting July 26th, all of the study's participants were given the vaccine immediately, instead of putting half in a delayed group.
These results don't mean that the world now has an Ebola vaccine. The vaccine needs to undergo further safety and efficacy testing.
The vaccine is also being tested on frontline health workers, Bertrand Draguez, medical director at Doctors Without Borders, said in a statement."
"These people have worked tirelessly and put their lives at risk every day to take care of sick people,
"If the vaccine is effective, then we are already protecting them from the virus. i
#HPV Vaccine Is Effective Against Multiple Cancer-Causing Strains The human papillomavirus vaccine, Cervarix, not only has the potential to prevent cervical cancer,
"The study confirms that targeting young adolescent girls before sexual debut for prophylactic HPV vaccination has a substantial impact on the incidence of high grade cervical abnormalities,"researcher Dan Apter,
They found that the vaccine was extremely effective in young women who had never been infected with HPV.
The women were followed for up to four years post-vaccination. The vaccine was distinctly more effective among ages 15-17 than ages18-25,
underscoring the value of vaccinating young adolescents, said Apter. The study is the final report from the Papilloma Trial Against Cancer in Young Adults (PATRICIA), a multinational clinical trial encompassing 14 countries in Europe, the Asia-Pacific region
The overall trial constituted the basis for approval of the Cervarix vaccine in Europe and the United states. While the trial did not investigate the vaccine's efficacy in males, sexually transmitted HPV causes anogenital and head and neck cancers in both males and females.
HPV-related head and neck cancers now number around 8, 400 in the United states, annually."
"The more adolescents are vaccinated, the closer we will be to eradicating high risk HPV viruses, "Apter said."
"So I think boys should also be vaccinated.""Cervical cancer is the fourth most common cancer among women.
The findings are detailed in the journal Clinical and Vaccine Immunology y
#Mastercard seeks to move digital money fast NEW YORK Mastercard wants to speed up digital payments. The financial services giant has launched just Mastercard Send,
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