Removing these toxic materials which include pesticides and endocrine disruptors such as bisphenol A (BPA) with existing methods is often expensive and time-consuming.
for Integrative Cancer Research. Eliana Martins Lima, of the Federal University of Goiás, is the other co-author.
Brandl says. hen we came up with the idea to use our particles to remove toxic chemicals, pollutants,
minimizing the risks of leaving toxic secondary products to persist in, say, a body of water. nce they switch to this macro situation where theye big clumps,
from environmental remediation to medical analysis. The polymers are synthesized at room temperature, and don need to be prepared specially to target specific compounds;
offering the example of a cheap testing kit for urine analysis of medical patients. The study also suggests the broader potential for adapting nanoscale drug-delivery techniques developed for use in environmental remediation. hat we can apply some of the highly sophisticated,
and an expert in nanoengineering for health care and medical applications. hen you think about field deployment,
and flowers while protecting farm workers--who in the past would apply pesticides by hand--from the toxicity of the chemicals."
#Doctors Can Now Successfully 3d Print A Knee joint While this footage isn as exciting as
Essentially, doctors at the Columbia University Medical center have been able to print a knee meniscus using a degradable plastic scaffold and a protein growth system.
there little that orthopedists can do to regenerate a torn knee meniscus, said study leader Jeremy Mao in a release. ome small tears can be sewn back in place,
which greatly increases the risk of arthritis. The scaffold isn just a plastic shell, however.
and shipping the scaffolds to patients and their doctors s
#Here Are connected The First Home Devices For Apple Homekit Apple Homekit is finally starting to roll out to actual consumers,
however, with a health-focused wristband that provides constant patient information for participants in medical studies and clinical field trials.
and the dedicated medical wearable unveiled today also monitors and reports information continuously, for better delivery of real-time actionable info to researchers and medical professionals.
Testing for the medical band begins this summer, according to Google, and it going to pursue regulatory approval for its use in medical contexts in partnership with academic institutions and drug companies, per Bloomberg.
This isn Google first move in building medical hardware; Google X is also creating contact lenses that can monitor blood glucose level to help in managing conditions like diabetes.
The competition is also eager to contribute to the medical research community pple has introduced Researchkit,
which allows studies to use iphones and ipads to gather participant data from a wider potential user pool, for instance o
#Turbocharging Photosynthesis to Feed the World Two down one to go. Researchers have completed the second of three major steps needed to turbocharge photosynthesis in crops such as wheat
and making sure the genes are stable says Dean Price a professor of medicine biology and environment at Australian National University.
Unfortunately, many common diagnostic tools, such as enzyme-linked immunosorbant assay (ELISA), require large and expensive readout instruments that can only be found in well-equipped hospital labs. Now,
Image via UCLATO conduct a traditional ELISA test, doctors place antigen samples from the patient onto a surface,
normally a small transparent plate resembling a honeycomb with 96 tiny wells. Specific antibodies are placed then into each well,
which can be analyzed by doctors to determine whether particular viruses are present. While that process may seem a bit complicated to us non-medical experts
and dramatically reduce diagnosis costs per patient compared to nonbatched or nonstandard tests. A traditional ELISA 96-well platewith the UCLA researcher new invention, the same steps are taken,
comparing 571 patient samples to FDA-approved samples of mumps, measles, and herpes simplex viruses 1 and 2. The platform achieved an accuracy of 99.6 percent in diagnosing mumps, 98.6 percent for measles,
and 99.4 percent each for herpes simplex 1 and 2. Schematic overview and different perpsectives of the colorimetric readeraccording to the research paper,
hand-held platform could assist healthcare professionals perform disease screening and vaccination tracking campaigns in resource-poor and field settings.
In addition to serving low-resource or remote areas, the researchers noted that intrinsic wireless connectivity can serve epidemic-related studies,
generating real-time, spatiotemporal maps of disease prevalence and immunity. e are always looking toward the next innovation,
and are looking to adapt the basic design of this ELISA cellphone reader to create smartphone-based quantified readers for other important medical tests,
said Dino Di Carlo, professor of bioengineering and one of the researchers on the team. t is quite important to have these kinds of mobile devices,
especially for administering medical tests that are done usually in a hospital or clinical laboratory, added lead researcher Aydogan Ozcan. t fantastic for an undergraduate to be first author on the publication,
physics and astronomy, to bioengineering, pathology and laboratory medicine. The Californa Nanosystems Institute and the Johnsson Comprehensive Cancer Center also contributed, with support from the National Science Foundation and the Howard hughes medical institute.
Since 3d printing technology is acknowledged already for being affordable and easily transportable to low-resource areas,
it is easy to imagine this kind of groundbreaking medical technology being used in remote, rural or developing countries, many
of which are at high risk for virus-related epidemics. And, given the incredibly high success rates of the clinical trials so far, it can only be hoped that this lifesaving device is put to good use as soon as humanly possible. a
It is designed to detect antigens in samples of blood with an ELISA test used to detect a number of bacteria,
it is used in many hospitals all over the world. Among other applications, ELISA tests can be used to determine
Blood samples are tested after specific antibodies that bind to antigens meet the blood in the embedded well portion of the plate.
The introduced antibodies contain enzymes whose substrates react chemically and cause a distinct change in color.
Any antigens that may be present can be detected from analyzing the color changes. So how does the handheld ELISA diagnostic tool work?
especially for administering medical tests that are done usually in a hospital or clinical laboratory, remarked Ozcan. his mobile platform can be used for point-of-care testing,
screening populations for particular diseases, or tracking vaccination campaigns in most resource-poor settings. It fantastic for an undergrad to be first author on the publication.
The FDA-approved well-plate readers used in clinical labs today were compared with the team handheld smartphone diagnostic in a UCLA clinical microbiology laboratory.
measles, and herpes simplex viruses 1 and 2 were all part of the dual ELISA tests. From 571 patient samples, the mobile platform was 99.6 percent accurate at diagnosing mumps, 98.6 percent for measles,
and 99.4 percent for both herpes simplex 1 and 2. ur team is focused on developing biomedical technologies that work with mobile platforms to assist with on-site testing
and health-care in disadvantaged or rural areas, Berg said. e are always looking toward the next innovation,
and are looking to adapt the basic design of this ELISA cellphone reader to create smartphone-based quantified readers for other important medical tests,
which represent a major milestone for designing materials with customized functions and structures for applications in medicine, optics, and energy.
#Polymer Nanobrushes Grab Selected Bacteria for Pathogen Detection A Texas A&m Agrilife Research engineer and a Florida colleague have developed a biosensor that can detect listeria bacterial contamination within two
The same technology can be developed to detect other pathogens such as E coli O157: H7, she said.
But listeria was chosen as the first target pathogen because it can survive even at freezing temperatures.
It is also one of the most common foodborne pathogens in the world and the third-leading cause of death from food poisoning in the U s."It can grow under refrigeration,
but it will grow rapidly when it is warmed up as its optimum growth temperature ranges from 30 to 37 degrees Celsius--86 to 98 degrees Fahrenheit,
000 National Science Foundation grant to continue their work on nanobrushes for pathogen detection n
#New Technique Uses Ultrasound Waves for Bulk Synthesis of Graphene A team of researchers from the University of Tabriz have developed a method to manufacture graphene, a crystalline allotrope of carbon, in a simple and economical manner.
where they create clothing that kills bacteria, conducts electricity, wards off malaria, captures harmful gas and weaves transistors into shirts and dresses. otton is one of the most fascinating and misunderstood materials,
which could help in warding colds, flu and other diseases. Two of Hinestroza students created a hooded bodysuit embedded with insecticides using metal organic framework molecules,
Malaria kills more than 600,000 people annually in Africa. While insecticide-treated nets are common in African homes
Other students have used MOFS to create a mask and hood capable of trapping toxic gases in a selective manner.
The nanoparticles infused with silver ions were utilized to attack Pseudomonas aeruginosa, disease-causing bacteria; E coli, a bacterial species that cause food poisoning;
Staphylococcus epidermis, bacteria that form toxic biofilms on plastics such as catheters in the human body; and Ralstonia, a genus of bacteria that contains various soil-borne pathogens.
All these bacteria were destroyed by the newly developed nanoparticles. Using this latest technique, researchers can easily modify the nanoparticle recipe to target certain microbes.
According to Alexander Richter, first author of the paper and a Ph d. candidate at NC State who received the 2015 Lemelson-MIT prize,
for Integrative Cancer Research. Eliana Martins Lima, of the Federal University of Goiás, is the other co-author.
Brandl says. hen we came up with the idea to use our particles to remove toxic chemicals, pollutants,
minimizing the risks of leaving toxic secondary products to persist in, say, a body of water. nce they switch to this macro situation where theye big clumps,
from environmental remediation to medical analysis. The polymers are synthesized at room temperature, and don need to be prepared specially to target specific compounds;
offering the example of a cheap testing kit for urine analysis of medical patients. The study also suggests the broader potential for adapting nanoscale drug-delivery techniques developed for use in environmental remediation. hat we can apply some of the highly sophisticated,
and an expert in nanoengineering for health care and medical applications. hen you think about field deployment,
The Saturas sensor provides accurate information for optimized irrigation to reduce water consumption with no stress to the plants and increases fruit production and quality.
raise promise for medicine but also concerns about"home-brewed"illegal drugs. Experts have called for tight control of organisms genetically modified to produce narcotics.
If you brew beer at home, then you are relying on microscopic yeast that turns sugars into alcohol.
and have the yeast do all the chemical steps required downstream to make your target therapeutic drug."
"Morphine plays a vital role in pain relief in many hospitals, but it requires a poppy harvest to manufacture.
The broad concept of using microscopic organisms to make drugs is not new in medicine.
Insulin for people with diabetes has been made in genetically modified bacteria for decades. But there are concerns these latest advances could allow a DIY drug lord to brew illegal narcotics in their home."
"In principle, anyone with access to the yeast strain and basic skills in fermentation would be able to grow morphine producing yeast using a a home-brew kit for beer-making,
#Bionic eye implant world first Surgeons in Manchester have performed the first bionic eye implant in a patient with the most common cause of sight loss in the developed world.
He is using a retinal implant which converts video images from a miniature video camera worn on his glasses.
He can now make out the direction of white lines on a computer screen using the retinal implant.
Mr Flynn said he was delighted"with the implant and hoped in time it would improve his vision sufficiently to help him with day-to-day tasks like gardening and shopping.
The Argus II implant manufactured by the US firm Second sight, has previously been used to restore some vision to patients who are blind as a result of a rare condition known as retinitis pigmentosa.
The operation, at Manchester Royal Eye Hospital, is the first time it has been implanted in a patient with age-related macular degeneration (AMD)
which affects at least half a million people in the UK to some extent. I met Ray Flynn last month,
on the morning of his surgery and he explained that although his retained his peripheral vision,
and was led by Paulo Stanga, consultant ophthalmologist and vitreo-retinal surgeon at Manchester Royal Eye Hospital and professor of ophthalmology and retinal regeneration at the University of Manchester.
In a test, two weeks after surgery, Mr Flynn was able to detect the pattern of horizontal,
vertical and diagonal lines on a computer screen using the implant. He kept his eyes closed during the test
so that the medical team could be sure that the visual information was coming via the camera on his glasses and the implant.
"The implant cannot provide any highly detailed vision -but previous studies have shown it can help patients to detect distinct patterns such as door frames and shapes.
Mr Flynn should learn how to interpret the images from the implant more effectively. Four more patients with dry AMD will receive the implant at Manchester Royal Eye Hospital,
as part of a clinical trial. Prof Stanga said:""We hope these patients will develop some central visual function
Gregoire Cosendai of Second sight Medical Products, described the AMD study as"totally groundbreaking research"."The trial is being held in the Manchester Clinical Research Facility-funded by the National Institute for Health Research and Wellcome Trust,
which aims to bring new drugs and medical devices to patients. Cathy Yelf, of the Macular Society, said:"
and for personalized medicine. The new optical attachment, which includes a lens, filter, mount and laser diode in a 3d-printed case, can image and size DNA molecules 50,000 times thinner than a human hair.
Scientists see the technology being used in remote laboratory settings to diagnose cancers and central nervous system disorders such as Alzheimer
and to detect drug resistance in infectious diseases. Bringing techniques and testing that is normally confined to a laboratory or hospital, out into the field,
or right into a patient home is a theme in Ozcan lab. His lab, s working on computational optical technologies that aim for microscopy, imaging, sensing and diagnostic applications,
unlike traditional techniques that are using instruments that you normally find in a lab or hospital,
and enable telemedicine and mobile health, but there also another angle that makes them attractive,
such as diagnosing and tracking Malaria and TB. It can also be applied to blood diseases, like sickle cell anemia,
or be used to look at contamination, for example in food or milk. The team has been able to convert the mobile phone into a sensitive E-coli or giardia detector,
one of the most frequently encountered pathogens, Ozcan said. It can also be used for simple tests that are done normally only at hospitals
such as total count of red or white blood cells. In the home and in the fielddoctors in the field, an convert a simple nurse office or a point of care office into an advanced testing infrastructure, Ozcan said. hey can,
for example, look at a Malaria infected patient, or TB infected patient and potentially decide on a drug choice based on some of the genetic testing copy number variations of certain genes that you would find in the sample taken from the patient. he technology also removes barriers to testing that cities
or small villages might have, including the cost of shipping and sending of specimen, or lack of experts in the immediate area. f you were to have these microscopes that are extremely cost effective,
a simple nurse or a healthcare technician can prepare specimen and image them, where the images are transferred then to an expert professional pathologist that is maybe 1,
For example, someone with diabetes who has chronic kidney problems. If the person needed to be tested every few hours, before a meal, after a meal,
it would be very valuable information for your doctor to be able to track your condition,
and our aging population. ext up the researchers plan to test their device in the field to detect the presence of malaria-related drug resistance.
or ELISA, is a diagnostic tool that identifies antigens such as viruses and bacteria in blood samples.
ELISA can detect a number of diseases, including HIV, West nile virus and Hepatitis b, and it is used widely in hospitals.
It can also be used to identify potential allergens in food, among other applications. A team of researchers from the California Nanosystems Institute at UCLA has developed a new mobile phone-based device that can read ELISA plates in the field with the same level of accuracy as the large machines normally found in clinical laboratories.
especially for administering medical tests that are done usually in a hospital or clinical laboratory, said Ozcan,
screening populations for particular diseases, or tracking vaccination campaigns in most resource-poor settings. It fantastic for an undergrad to be first author on the publication.
Traditional ELISA testing is performed with small transparent plates that resemble honeycombs, typically with 96 tiny wells. Samples are placed in the wells first,
followed by small amounts of fluid containing specific antibodies that bind to antigens in the samples.
These antibodies are linked to enzymes, so when a substance containing the enzyme substrate the molecule the enzyme acts upon is added,
and quantify any antigens that may be present. The new device which is created with a 3d printer
The ELISA tests included those for mumps, measles, and herpes simplex viruses 1 and 2. With a total of 571 patient samples used in the comparison,
the mobile platform achieved 99.6 percent accuracy in diagnosing mumps, 98.6 percent for measles, and 99.4 percent each for herpes simplex 1 and 2. ur team is focused on developing biomedical technologies that work with mobile platforms to assist with on-site testing
and health-care in disadvantaged or rural areas, Berg said. e are always looking toward the next innovation,
and are looking to adapt the basic design of this ELISA cellphone reader to create smartphone-based quantified readers for other important medical tests,
The UCLA team included researchers from electrical engineering, physics and astronomy, bioengineering, pathology and laboratory medicine,
and surgery, as well as the California Nanosystems Institute and the Jonsson Comprehensive Cancer Center. The other authors on the paper were UCLA graduate students Bingen Cortazar, Derek Tseng, Haydar Ozkan, Raymond Yan-Lok Chan, and Steve Feng;
postgraduate scholar Qingshan Wei; undergraduates Jordi Burbano and Qamar Farooki; and Michael Lewinski, an adjunct faculty in UCLA bioengineering department.
For initial studies, silver was used to fill the tubes via nano-injection. Various experiments found the shape
while it is kept at a consistent warmth of 101.5°F (38°C). The three-plus weeks the manure is kept at that temperature is to guarantee any pathogens would be killed off,
But state-of-the-art processes are expensive result in a significant reduction in a power plant's output and yield toxic byproducts.
#UK scientists invent BIONIC EYE to save Ray Flynn's sight A revolutionary bionic eye implant has restored the sight of a British Man ray Flynn, 80, from Audenshaw,
Surgeons at Manchester Royal Eye Hospital implanted a chip at the back of Mr Flynn eye in a four-hour procedure last month.
Surgeons will now insert the Argus II retinal implant into more patients over the coming months to demonstrate that it can work for a variety of patients.
000 people in Britain, 85 per cent of them with the dry form of the disease.
Professor Paulo Stanga, consultant ophthalmologist at the Manchester Royal Eye Hospital, said: r Flynn progress is truly remarkable.
and his brain now needs to get use to interpreting it. he Argus II retinal implant was used previously on 130 patients with the rare eye disease retinitis pigmentosa.
developed by US firm Second sight Medical Products, might be used for patients with other vision problems.
In medicine you talk of drug delivery-we do flavour delivery."."The sensory profile of Douxmatok is literally the same as sugar."
At the same time, however, the mechanical stress on the products needs to be kept as low as possible,
and stress signals that is otherwise invisible to the human eye. The crop health monitoring imagery utilized by Farmlogs shows information that is actionable
#World First Malaria Vaccine Approved and it Will be Not-for-Profit The world first malaria vaccine has been given approval by a European medical agency for future use in Sub-saharan africa, where more than a quarter million children under the age of five die every year from the disease.
European regulators examined phase III clinical trial results involving more than 16,000 young children conducted by research centers in eight African countries (Burkina faso, Gabon, Ghana, Kenya, Malawi, Mozambique, Nigeria
Glaxosmithkline Vice president for Africa told CNN. t is the first time anyone ever has been able to make a vaccine against a parasite.
Perhaps most impressive, Glaxosmithkline, the pharmaceutical company that worked on this vaccine for 30 years, and received $200 million from the Gates Foundation, is making RTS, S available as a nonprofit drug.
with all that money going back into further research for a malaria vaccine that could be even more effective.
and expects to invest a further $200 to $250 million until the vaccine is ready for market.
With this approval from the European Medicines Agency Friday, the vaccine next will be considered by the World health organizations,
and if they will use the vaccine, along with current Malaria prevention techniques, like bed nets. 80%of the children involved in the clinical trials were protected also by insecticide treated bed nets.
RTS S, also known as Mosquirix, was administered to children aged 6 weeks to 17 months in three doses. Over the first 18 months following three doses of RTS, S,
malaria cases were reduced by almost half in children aged 5-17 months at the time of first vaccination and by 27%in infants aged 6-12 weeks.
At study end, over four years of follow-up in children RTS, S reduced malaria cases by 39,
In areas of the highest malaria burden, more than 6 000 clinical malaria cases were prevented over the study period for every 1, 000 children vaccinated
#The Case for Long-Duration Storage: Net Electricity Load in Calif. Is 5 Years Ahead of Schedule On January 11, 2015, a rather unremarkable Sunday earlier this month,
If the rods and cones that make up the photoreceptors of the eye fail because of injury or illness,
and has restored already the sight of people with a specific form of blindness. About 200,000 people in the US have inherited diseases that cause problems for the photoreceptors in their eye.
From strings of lights adding holiday cheer to artificial sunlamps alleviating seasonal affective disorder, they brighten our days.
and nanotechnology as well as the completion of a device that may improve quality of life in indoor settings, from hospitals to underground parking garages.
how proteins aggregate in the earliest stages of diseases like Alzheimer and Huntington, has begun just.
Understanding disease progression at the single-molecule level could help identify when early intervention might be advantageous.
non-biodegradable and potentially toxic materials-are discarded at an alarming rate in consumers'pursuit of the next best electronic gadget.
However, gallium arsenide can be environmentally toxic, particularly in the massive quantities of discarded wireless electronics.
says the new process greatly reduces the use of such expensive and potentially toxic material."
"The researchers used the nanoparticles to attack E coli, a bacterium that causes food poisoning; Pseudomonas aeruginosa, a common disease-causing bacterium;
Ralstonia, a genus of bacteria containing numerous soil-borne pathogen species; and Staphylococcus epidermis, a bacterium that can cause harmful biofilms on plastics-like catheters-in the human body.
The nanoparticles were effective against all the bacteria. The method allows researchers the flexibility to change the nanoparticle recipe in order to target specific microbes.
"The researchers used the nanoparticles to attack E coli, a bacterium that causes food poisoning; Pseudomonas aeruginosa, a common disease-causing bacterium;
Ralstonia, a genus of bacteria containing numerous soil-borne pathogen species; and Staphylococcus epidermis, a bacterium that can cause harmful biofilms on plastics-like catheters-in the human body.
The nanoparticles were effective against all the bacteria. The method allows researchers the flexibility to change the nanoparticle recipe in order to target specific microbes.
#Biomedical breakthrough: Carbon nanoparticles you can make at home Abstract: Researchers have found an easy way to produce carbon nanoparticles that are small enough to evade the body's immune system,
"The team tested the therapeutic potential of the nanoparticles by loading them with an anti-melanoma drug
In further experiments, the researchers found they could alter the infusion of the particles into melanoma cells by adjusting the polymer coatings.
"This is a versatile platform to carry a multitude of drugs-for melanoma, for other kinds of cancers and for other diseases,
so you can do multidrug therapy with the same particles.""""By using defined surface chemistry,
and are affiliated with Carle Foundation Hospital in Urbana, Illinois.##For more information, please click herecontacts:
The paper,"Tunable luminescent carbon nanospheres with well-defined nanoscale chemistry for synchronized imaging and therapy,"is available online:
2015cellulose from wood can be printed in 3-D June 17th, 2015new Sensors Measure Blood Anticoagulation Drug June 17th, 2015discoveries Scientists film shock waves in diamond:
Method could be useful in developing green energy and a better understanding of rust June 18th, 2015new Sensors Measure Blood Anticoagulation Drug June 17th,
Method could be useful in developing green energy and a better understanding of rust June 18th, 2015new Sensors Measure Blood Anticoagulation Drug June 17th,
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