#DNA mutations get harder to hide Rice university researchers have developed a method to detect rare DNA mutations with an approach hundreds of times more powerful than current methods.
and lead author and graduate student J. Sherry Wang applied their new molecular tools to 44 DNA samples with known cancer-related single-nucleotide variants.
as a significant step toward advancing personalized medicine. The ability to accurately find mutations that are biomarkers for disease will help clinicians determine treatment paths for patients,
Zhang said. It may also help identify rare mutations and subtypes of infectious diseases as well as drug-resistant strains.
A single-nucleotide variant occurs when one of the four basic components that make up DNA
but mutations can leave the body vulnerable to disease, or even be the root cause.
The ability to accurately find rare single-nucleotide mutations is becoming increasingly important as scientists drill down into genomes to find biomarkers for early cancer detection. ee trying to solve the needle-in-a-haystack problem,
The needle youe looking for might be a cancer-mutation DNA or bacterial-pathogen DNA,
when there not as much cancer DNA floating around, he said
#A new kind of wood chip: collaboration could lead to biodegradable computer chips Portable electronics typically made of nonrenewable,
non-biodegradable and potentially toxic materials are discarded at an alarming rate in consumerspursuit of the next best electronic gadget.
However, gallium arsenide can be environmentally toxic, particularly in the massive quantities of discarded wireless electronics.
and potentially toxic material. e made 1, 500 gallium arsenide transistors in a 5-by-6 millimeter chip.
as a result of human exploitation and disease-related die offs, says Joshua Miller, Phd student in the Department of Biological sciences and lead author on the study. hus,
which allows for a better therapeutic potential. The team of researchers tested the therapeutic potential of these carbon nanoparticles by loading them with an anti-melanoma drug
and mixing them in a topical solution that was applied to pig skin. However, scientists have to make sure they coated particles properly,
Scientists also found that they can alter the infusion of the particles into melanoma cells by adjusting the polymer coatings.
It is a very versatile platform to treat melanoma, other kinds of cancers and other diseases.
as well as to make it carry several different drugs at the same time to allow for a multidrug therapy with the same particles.
which will eventually lead to innovative drug therapies for cancer and other diseases i
#Actuators that mimic ice plants Engineers developing moveable robot components may soon take advantage of a trick plants use.
works on growing metal organic frameworks onto cotton samples to create a filtration system capable of capturing toxic gas,
where they create clothing that kills bacteria, conducts electricity, wards off malaria, captures harmful gas and weaves transistors into shirts and dresses. otton is one of the most fascinating and misunderstood materials,
which could help in warding colds, flu and other diseases. Two of Hinestroza students created a hooded bodysuit embedded with insecticides using metal organic framework molecules,
Malaria kills more than 600,000 people annually in Africa. While insecticide-treated nets are common in African homes
Other students have used MOFS to create a mask and hood capable of trapping toxic gases in a selective manner.
to attack E coli, a bacterium that causes food poisoning; Pseudomonas aeruginosa, a common disease-causing bacterium; Ralstonia, a genus of bacteria containing numerous soil-borne pathogen species;
and Staphylococcus epidermis, a bacterium that can cause harmful biofilms on plastics like catheters in the human body.
The nanoparticles were effective against all the bacteria. The method allows researchers the flexibility to change the nanoparticle recipe in order to target specific microbes.
#New material opens possibilities for super-long-acting pills Medical devices designed to reside in the stomach have a variety of applications,
However, these devices, often created with nondegradable elastic polymers, bear an inherent risk of intestinal obstruction as a result of accidental fracture or migration.
Now, researchers at MIT Koch Institute for Integrative Cancer Research and Massachusetts General Hospital (MGH) have created a polymer gel that overcomes this safety concern
which is a medical emergency potentially requiring surgical intervention, says Koch Institute research affiliate Giovanni Traverso,
as there is a greater risk for fracture if a device is too large or too complex.
a professor of medical science and engineering at Brown University who was not involved with this study. his is a very smart approach.
patientsadherence to long-term therapies for chronic illnesses is only 50 percent in developed countries, with lower rates of adherence in developing nations.
Medication nonadherence costs the U s. an estimated $100 billion every year, the bulk of which comes in the form of unnecessary hospitalizations.
The researchers also say that single-administration delivery systems for the radical treatment of malaria
and other infections could significantly benefit from these technologies. Source: MIT, written by Kevin Leonard e
Peter Coker, chief executive of Martin told Reuters. aturally for the ambulance service getting to a point of importance of rescuing people in the shortest possible time is crucial. he jetpack will ship for emergency services in the second-half of 2016,
< Back - Next >
Overtext Web Module V3.0 Alpha
Copyright Semantic-Knowledge, 1994-2011