| Asthma (130) |  |
| Pneumonia (55) | |
With common pathogens such as E coli and the pneumonia bug K. pneumoniae developing resistance to our antibiotics of last resort, leading pharmacologists, clinicians and epidemiologists say we risk being cast back to a time
another Chlamydia pneumoniae causes pneumonia. In this study the researchers used four experimental groups to compare genome-wide expression changes in vascular tissue.
#Topical antibiotics may raise pneumonia risk University of Melbourne rightoriginal Studyposted by David Scott-Melbourne on October 13 2014patients in hospital intensive care units have a higher risk of developing pneumonia
The findings contradict previously published research that topical antibioticsâ##medication applied to the patient s airwayâ##would decrease pneumonia rates.
Ventilator-associated pneumonia develops in approximately 20 percent of patients in intensive care units (ICUS) who are receiving prolonged medical ventilation.
However in the control groups of these published clinical trials of topical antibiotics in this patient group the pneumonia rates were as high as 40 percent.
For a new study published in the journal CHEST researchers analyzed 206 international publications evaluating pneumonia prevention methods in ICUÂ##s from the last 30 years.
The new findings will help improve understanding of how to evaluate pneumonia prevention methods in the ICU says associate professor James Hurley from the University of Melbourne.
Use of topical antibiotics increases the pneumonia risk in ICU patients by disrupting the balance of bacteria
##This surprising finding is not apparent in any one study examined in isolationâ##it requires a meta-analysis of the control group pneumonia rates in all 206 studies to demonstrate these findings.
Pneumonia is acquired commonly by ICU patients leads to longer stays in intensive care and can also increase mortality risk.##
###Therefore it appears topical antibiotics used in an effort to prevent pneumonia in the ICU are a hazard
Preying on skin cells on the body, the mites trigger allergies and breathing difficulties among 45 percent of those who suffer from asthma, according to some studies.
and holds no guarantee of success. Alleviate mite-induced asthma ur research explores a novel approach to treating mite allergy in
public health professor and a contributing author of the paper. his work suggests a way forward to alleviate mite-induced asthma in allergy sufferers.
leading to severe bronchiolitis, says Raymond Pickles, associate professor of microbiology and immunology. ut what wee now shown is that RSV has increased an ability to cause airway obstruction because, during an RSV infection,
and its effect on epithelial-cell shedding that makes RSV by far the most common cause of bronchiolitis in otherwise healthy young children.
It causes more than 600000 deaths a year from cryptococcal pneumonia and meningoencephalitis accounting for a third of all AIDS-related deaths.
ADAMM Intelligent Asthma Management Wearable Walking through expansive, smoke-filled casinos, traversing the miles and miles of exhibitors,
this editor was afraid his asthma might flare up as he made his way around CES in Las vegas last week.
asthma would be the least of his worries. ADAMM (Automated Device for Asthma Monitoring and Management) is an upcoming wearable developed by Rochester, NY based Health care Originals.
Measuring about the diameter of a hockey puck, this smart patch can not only tell when the wearer is experiencing an asthma attack by measuring heart rate,
if their asthma is starting to flare up, and even then, they often lack the discipline to use their inhaler.
ADAMM can help ensure that parents can monitor for asthma flare-ups, even when they are away from their kids.
instead there are hard data on how much it will cost to treat the asthma cases that are caused by the extra pollution.
colds in children can cause middle-ear infections or increase the likelihood of developing asthma.
Asthma sufferers, in turn, can find that catching a cold worsens their symptoms.""From that perspective, rhinovirus deserves to be attacked with the modern tools we have available to us,
and Tibetan medicine for a wide range of conditions including impotence, asthma and cancer. The peculiar life cycle of the fungus has earned also it the names'winter worm, summer grass'and'caterpillar fungus'.
asthma and diabetes can be all be detected in the breath. Using light to smell might be a little counterintuitive,
and gastrointestinal infections, including pneumonia, sepsis, gastritis, and Legionnairesdisease. One advantage of the engineered phages is that unlike many antibiotics,
#Unexpected Discovery Offers Insight into Mechanisms of Asthma, Other Diseases A new study from the Harvard T. H. Chan School of Public health reveals an unexpected discovery In people with asthma,
But the study showed that, in asthma, the opposite is true. The physics of biologythe researchers decided to look at the detailed shape and movement of cells from the asthmatic airway because, according to Fredberg,
and the fact that no one knows what causes asthma, which afflicts more than 300 million people worldwide it made sense to look at the shape and movement of epithelial cells,
The study included lead authors Jin-Ah Park and Jae Hun Kim, research scientists in the Department of Environmental Health who study asthma,
and Jeffrey M. Drazen, a pulmonologist and professor in the department, who studies echanotransductionin asthma how the bronchial constriction of asthma might trigger cell changes in the epithelium.
whether asthma causes the cells to unjam, or the unjamming of the cells causes asthma. t a very big question to figure out why this particular cell shape
and movement is said happening Park. e know that asthma is related to genes, environment, and the interaction between the two,
but asthma remains poorly understood. hatever the reason, knowing more about how these cells jam
and unjam is said important Fredberg, because epithelial cells play a prominent role not just in asthma,
but in all processes involving cell growth and movement, including organ development, wound healing, and, importantly, cancer.
The findings open the door to new possibilities for developing drugs to fight asthma as well as other diseases
This computer system can be tailored to many different medical conditions including acute lung injury, pneumonia, and post-rehabilitation illnesses like neuropathy. e are at a very exciting time,
or debilitating lung conditions including cancer, tuberculosis, asthma and cystic fibrosis. But the Respitetm nebulizer also has the potential to be used to administer insulin to people with diabetes
#Lab on a Chip Acoustofluidic Sputum Liquefaction Device for Safe Asthma and Tuberculosis Diagnostics A device to mix liquids utilizing ultrasonics is the first and most difficult component in a miniaturized system for low-cost analysis
of sputum from patients with pulmonary diseases such as tuberculosis and asthma. The device, developed by engineers at Penn State in collaboration with researchers at the National Heart, Lung,
or around 19 million people, have asthma, and in undeveloped regions where TB is still a widespread
and treatment approaches for patients with pulmonary diseases, we have to analyze sample cells directly from the lungs rather than by drawing blood,
different drugs are used to treat different types of asthma patients. If you know what a person immunophenotype is
Stewart J. Levine, a Senior Investigator and Chief of the Laboratory of Asthma and Lung Inflammation in the Division of Intramural Research at NHLBI, said his on-chip sputum liquefier is a significant advance regarding our goal
This will allow health care providers to individualize asthma treatments for each patient and advance the goal of bringing precision medicine into clinical practice.
This research was supported by the American Asthma Foundation Scholar Award the National Science Foundation, and the NHLBI Division of Intramural Research.
including influenza and pneumonia. A report on the experiments is published in the September 1 issue of the journal Anesthesiology.
and shortness of breath (dyspnea. e plan to submit these data to the FDA this year to support alectinib as a potential new option for people
or higher adverse event was shortness of breath (dyspnea; 4 percent. About the NP28761 Study NP28761 is a Phase I/II North american, single-arm, open-label,
5 percent) and shortness of breath (dyspnea; 3 percent. About Alectinib Alectinib (RG7853/AF-802/RO5424802/CH5424802) is an investigational oral medicine created at Chugai Kamakura Research Laboratories
US researchers have developed a new low-cost lab-on-a-chip device to aid analysis of sputum from patients with pulmonary diseases such as tuberculosis and asthma.
and provide alternate treatment approaches for patients with pulmonary diseases.""""Current analysis method has said several disadvantages
'What happens when a member of the team comes down with cellulitis or pneumonia? We have got to use telemedicine to tele-mentor them on the diagnosis and treatment.
Historically, CP has been attributed to an array of factors such as asphyxia, stroke, and infections in the developing brains.
Historically, CP has been attributed to an array of factors such as asphyxia, stroke, and infections in the developing brains.
Indeed, the so-called"patient-centered medication safeguard"could be a valuable tool for providers who deal with the millions of patients who take multiple medications each day to manage conditions such as high blood pressure, asthma, COPD, heart disease and diabetes.
The number of years lived with disability have increased in almost every country, attributable to the growth of chronic diseases such as cardiovascular and respiratory diseases, cancer, back pain, mental health disorders, dementia, road injuries, HIV
non-life threatening issues (think Viagra) rather than common illnesses like high blood pressure and asthma. The pharmaceutical industry seems to be caught between a rock
The cost of medications for asthma, high blood pressure and diabetes went up more than 10 percent each,
the asthma drug Albuterol sulfate went up more than 3, 400 percent and the antibiotic Coxycycline jumped 6, 300 percent.
Diarrheal and respiratory diseases are some of health experts'main concerns in the earthquake's aftermath."
and new neurons grown by asthma drug IT as good as new. An asthma drug has rejuvenated rat brains,
making old rats perform as well as young ones in tests of memory and cognition. Our brains slowly degenerate as we age.
A drug called montelukast (Singulair), regularly prescribed for asthma and allergic rhinitis, blocks these receptors, so Aigner and his colleagues tested it on young and old rats.
The team used oral doses equivalent to those taken by people with asthma. The older animals were 20 months old perhaps between 65 and 75 in human years.
and antibiotic-resistant bacteria such as Klebsiella pneumonia or Escherichia coli i
#Device may detect urinary tract infections faster Sepsis is a major killer and accounts for about half of the hospital deaths in the US by some estimates.
"For elderly people who have flu or pneumonia, their immune systems are activated, but maybe they can't fight anything else,
and cause pneumonia and infections in the bloodstream and in surgical wounds, according to the CDC.
and gastrointestinal infections, including pneumonia, sepsis, gastritis, and Legionnaires'disease. One advantage of the engineered phages is that unlike many antibiotics,
%shortness of breath (3. 7%)and pneumonia (3. 7%).Prof Choueiri said:""The METEOR results are important from a clinical and scientific point of view.
#Researchers'"hugely exciting"asthma discovery Cardiff scientists have identified for the first time the potential root cause of asthma and an existing drug that offers a new treatment.
and the Mayo Clinic (USA), describe the previously unproven role of the calcium sensing receptor (Casr) in causing asthma,
The team used mouse models of asthma and human airway tissue from asthmatic and non-asthmatic people to reach their findings.
cigarette smoke and car fumes and airways twitchiness in allergic asthma. ur paper shows how these triggers release chemicals that activate Casr in airway tissue
and drive asthma symptoms like airway twitchiness, inflammation, and narrowing. Using calcilytics, nebulized directly into the lungs,
Director of research and Policy at Asthma UK, who helped fund the research, said: his hugely exciting discovery enables us, for the first time,
to tackle the underlying causes of asthma symptoms. Five per cent of people with asthma don respond to current treatments so research breakthroughs could be life changing for hundreds of thousands of people. f this research proves successful we may be just a few years away from a new treatment for asthma,
and we urgently need further investment to take it further through clinical trials. Asthma research is chronically underfunded;
there have only been a handful of new treatments developed in the last 50 years so the importance of investment in research like this is absolutely essential.
While asthma is controlled well in some people, around one-in-twelve patients respond poorly to current treatments.
the identification of Casr in airway tissue means that the potential for treatment of other inflammatory lung diseases beyond asthma is immense.
Professor Riccardi and her collaborators are now seeking funding to determine the efficacy of calcilytic drugs in treating asthmas that are especially difficult to treat,
particularly steroid-resistant and influenza-exacerbated asthma, and to test these drugs in patients with asthma.
Calcilytics were developed first for the treatment of osteoporosis around 15 years ago with the aim of strengthening deteriorating bone by targeting Casr to induce the release of an anabolic hormone.
potentially accelerating the time it takes for them to be approved for use asthma patients. Once funding has been secured,
and potentially stop asthma from happening in the first place, added Professor Riccardi. The study was part-funded by Asthma UK
the Cardiff Partnership Fund and a BBSRC parking Impactaward d
#Transparent Armor based on Spinel Could Also Ruggedize Your Smart Phone Imagine a glass window that tough like armor,
asthma and other life-threatening lung diseases. o our knowledge, this is the first biodegradable gene delivery system that efficiently penetrates the human airway mucus barrier of lung tissue,
and asthma is increasing. Now scientists say that since they can explain that the pathogen-induced epigenomic changes mediated by ATF7 maintain for a long period of time,
Genome pioneer Craig Venter led a team that manufactured a genome for a germ that causes pneumonia in cows,
#Researchers look to exploit females natural resistance to infection Researchers have linked increased resistance to bacterial pneumonia in female mice to an enzyme activated by the female sex hormone estrogen.
Now an international team of scientists has shown that increased resistance to bacterial pneumonia in female mice is linked to the enzyme nitric oxide synthase 3 (NOS3.
Ultimately this work could be especially useful in reducing risk of secondary bacterial pneumonias during seasonal
and that can indeed improve resistance to pneumonia in our mouse model l
#Researchers turn to 3-D technology to examine the formation of cliffband landscapes A blend of photos
This breakthrough in the understanding of the mechanisms underlying allergy could have important applications in the treatment of asthma and other allergic diseases such as eczema and allergic rhinitis.
By triggering the chain reactions responsible for the allergic symptoms of asthma eczema or allergic rhinitis these cells have an essential role in allergy.
in order to reduce the allergic reactions triggered by ILC2 represents a promising strategy for the treatment of asthma and other allergic diseases.
#Double blast to ward off pneumonia: Dry powder inhaler formulation Despite advances in vaccination and antimicrobial therapy, community-acquired pneumonia remains a leading cause of morbidity and mortality, even in highly developed countries.
Desmond Heng, Reginald Tan and co-workers at the A*STAR Institute of Chemical and Engineering sciences have developed now a dry powder inhalation formulation to treat bacterial infections associated with this disease1.
Community-acquired pneumonia, a type of lung inflammation contracted outside of a hospital or nursing-home setting, is caused most often by infections with bacteria, such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus.
"Our follow-up microbial assays show that a concentration as low as one microgram per milliliter is enough to inhibit three of the bacteria known to cause this type of pneumonia.""
""We found that it is feasible to package the CIP-BP dry powder in an inhaler that can treat bacterial infections associated with community-acquired pneumonia,
The delivery of CIP and BP via dry powder inhalers may become a novel and useful strategy for treating patients with community-acquired pneumonia a
if a cough is just a cold or something more serious, like pneumonia or asthma.
They help people participate in tests for Parkinson, diabetes, cardiovascular disease, asthma, and breast cancer. Apple Jeff Williams came out on stage today at the Apple Watch event to show off Researchkit.
##As an example of how to manage the risks of including apps in connected systems Tighe cites the Verihaler which Sagentia has developed to monitor patient adherence to treatment for asthma or chronic obstructive pulmonary disease (COPD.
##As an example of how to manage the risks of including apps in connected systems Tighe cites the Verihaler which Sagentia has developed to monitor patient adherence to treatment for asthma or chronic obstructive pulmonary disease (COPD.
and Increase targeted tree plantings in neighborhoods with high asthma rates. Over four months 1436 respondents contributed over 30000 responses and 464 new ideas to the survey.
or Streptococcus pneumonia survived and showed no signs of toxicity pleasant surprise to Lewis and his colleagues.
Several earlier studies have established that copper is very effective against a host of bacteria that cause a variety of human diseases including stomach ailments, pneumonia,
#New breath test may detect pneumonia LONDON: A simple breath test can now detect if a critically ill patient is infected with pneumonia or not.
Chemically analysing breath specimens from patients in intensive care can reveal bacterial infection in the lower respiratory tract of ventilated patients at risk of developing pneumonia.
Though the study is at an initial stage, the results so far look promising and could potentially have a huge effect on clinical practice as healthcare associated infections are a major issue worldwide."
"Pneumonia can be treated with antibiotics but there are two major problems-it can be difficult to detect
In the most severe cases, bacterial poisoning causes severe disease and syndromes like sepsis, meningitis, pneumonia,
US researchers have found that peat fires in the southern states during the summer of 2008 caused a spike in emergency room visits for heart failure and asthma-related respiratory complications.
and can cause fever, breathing problems, pneumonia and kidney failure. The virus has spread primarily through contact with camels,
Earlier research on individual diseases such as ADHD and asthma suggested a connection between birth season and incidence,
For example, the study authors found that asthma risk is greatest for July and October babies.
which can ultimately result in pneumonia and kidney failure, according to the CDC. So far, 16 have died in the South korea outbreak
asthma and diabetes can be detected in this way, even before external symptoms are showing. owever, Anstie told Bioscience Technology, ther conditions,
#Uncovering the Spread of Bacteria in Pneumonia Northwestern Medicine scientists have discovered the role a toxin produced by a pneumonia-causing bacterium plays in the spread of infection from the lungs to the bloodstream in hospitalized patients. rior to this study,
Dr. Hauser and his team used a mouse model of Pseudomonas aeruginosa (PA) pneumonia to examine how the bacterium uses its secretion system to inject a toxin, called Exos, into cells.
or the lung of a person who has PA pneumonia and block this process. If we can block these processes,
we may be able to prevent bacteria from disseminating to the bloodstream during pneumonia, said Dr. Hauser, also a member of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
Next, Dr. Hauser plans to continue studying the mechanism of how Exos leads to the formation of FOCI. his research might have implications for other bacteria that frequently cause pneumonia
Apple launched its Researchkit program in March with five apps to investigate Parkinson's, asthma, heart disease, diabetes and breast cancer.
Elizabeth Ortiz, a 48-year-old New york nurse with asthma, measures her lung power each day by breathing into an inexpensive plastic device.
She types the results into the Asthma Health app which also asks if she's had difficulty breathing or sleeping,
and there's a high rate of asthma in my community, "said Ortiz, who said she already used her iphone"constantly"for things like banking and email."
and anyone else who suffers from asthma.""None of the apps test experimental drugs or surgeries.
"Diseases like asthma are complicated very. They're not caused by a single gene or environmental influence,"said Eric Schadt,
a genomics professor who's using an iphone app to study asthma at New york's Icahn School of medicine at Mount sinai."
Apple launched its Researchkit program in March with five apps to investigate Parkinson's, asthma, heart disease, diabetes and breast cancer.
Elizabeth Ortiz, a 48-year-old New york nurse with asthma, measures her lung power each day by breathing into an inexpensive plastic device.
She types the results into the Asthma Health app which also asks if she's had difficulty breathing or sleeping,
and there's a high rate of asthma in my community, "said Ortiz, who said she already used her iphone"constantly"for things like banking and email."
and anyone else who suffers from asthma.""None of the apps test experimental drugs or surgeries.
#Asthma Could Be cured Within 5 Years With This New Breakthrough Asthma could be cured in five years
to tackle the underlying causes of asthma symptoms, said Dr Samantha Walker, Director of research and Policy at Asthma UK. f this research proves successful we may be just a few years away from a new treatment.
Scientists are hopeful that patients can take the drug to prevent asthma attacks before they start ending the need to constantly carry an inhaler to end symptoms once an attack has started.
Walker added, ive percent of people with asthma don respond to current treatments, so research breakthroughs could be life-changing for hundreds of thousands of people.
the treatment that could effectively cure asthma would be available in the next 5 years. The research, funded by Asthma UK, the Cardiff Partnership Fund,
and a Biotechnology and Biological sciences Research Council award, was published in the Science Translational Medicine journal in April.
From sensors that aim to halt asthma in its tracks, to home monitors that warn the family
The Best Fitness Tracker Brands Derailing asthma Long before someone has an asthma attack there are warning signs that their respiratory function is going downhill.
which makes a new asthma monitor called the Adamm. But children and even adults often don't even realize they are having trouble breathing,
who has told asthma Live Science. Adamm is a wearable, three-sensor monitor that will hit the market later this year.
#Could There Be An Asthma Cure Within Five Years? A recent study has revealed a breakthrough in asthma research might be on the horizon.
Following extensive research carried out across a number of institutions, it has been discovered that protein molecules-known as calcium-sensing receptors-have a vital role in asthma.
Although they have not previously been used to treat asthma, there is already medication available (calcilytics) that could be used to block these proteins.
In asthmatics, the immune system essentially misidentifies harmless substances, such as pollen for example, as a threat. The airways then restrict in an attempt to keep the armfulsubstances from entering the lungs leading to the body facing constricted airways and
Based on the study, the researchers concluded that this is one of the main reasons for the excessive inflammatory responses that occur in people with asthma.
This discovery has led the researchers to believe that new treatment options for asthma could be found some time in the near future.
or combination of treatments, that will help people to deal with asthma once and for all. When approached by our research team,
when talking about an asthma cure. hilst this study offers hope to over 5%of asthma sufferers who do not respond to any of the treatments currently available,
Director of research and Policy at Asthma UK, was optimistic about the future potential this study has:
to tackle the underlying causes of asthma symptoms. 5%of people with asthma don respond to current treatments so research breakthroughs could be life changing for hundreds of thousands of people.
whether the use of calcilytics is a viable treatment method for asthma. There are a number of areas that large-scale clinical trials could help clear up.
Also, whilst the asthma sufferers who took part in this study had increased an number of receptors,
and whether the same is true for all people with asthma. However, the study does raise some hope of new asthma treatments in the future,
something that should give hope to millions of asthma sufferers worldwide. The study was published by researchers from Cardiff University, The Open university, the University of Manchester, the University of California
the San francisco School of medicine and King College, London. It was funded by Asthma UK, the Cardiff Partnership Fund, Marie Curie Initial Training Network, the Biotechnology and Biological sciences Research Council and the US National institutes of health t
#Microscopic Sonic Screwdriver Invented A team of engineers have created tiny acoustic vortices and used them to grip
as well as respiratory tract infections, including pneumonia and influenza. Publishing the results in Science Translational Medicine, the team observed no serious side effects.
Studies on mice and rats showed the drug could also be used to prolong survival in particularly severe pneumonia,
which had been used in the treatment of asthma also has the ability to cause weight loss
In 2013 the researchers discovered that amlexanox an off-patent drug currently prescribed for the treatment of asthma and other uses reversed obesity diabetes and fatty liver in mice.
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