#Researchers discover how opium poppies synthesize morphine From left: Peter Facchini, professor in biological sciences, Jill Hagel, research associate,
the drug led to abnormal development of microchambers, including decreased size, problems with muscle contraction and lower beat rates compared with heart tissue that had not been exposed to thalidomide."
and other UC Berkeley researchers publicly debuted a system of beating human heart cells on a chip that could be used to screen for drug toxicity.
However, that heart-on-a-chip device used pre-differentiated cardiac cells to mimic adult-like tissue structure.
said Stride. hen we expose it to ultrasound that will break the shell and release the drug. ew dawn for ADCS,
The team has been able to convert the mobile phone into a sensitive E-coli or giardia detector,
The research, ield-Portable Smartphone Microscopy Platform for Wide-field Imaging and Sizing of Single DNA Molecules, was presented at the Optical Society Conference on Laser and Electro optics (CLEO) 2015 h
#New Chip Makes Testing for Antibiotic-resistant Bacteria Faster, Easier We live in fear of uperbugs infectious bacteria that don respond to treatment by antibiotics,
Now Ph d. researcher Justin Besant and his team at the University of Toronto have designed a small and simple chip to test for antibiotic resistance in just one hour,
Their work was published this week in the international journal Lab on a Chip. Resistant bacteria arise in part because of imprecise use of antibioticshen a patient comes down with an infection,
and biomedical engineering to design a chip that concentrates bacteria in a miniscule spaceust two nanolitres in volumen order to increase the effective concentration of the starting sample.
Electrodes built directly into the chip detect the change in current as resazurin changes to resorufin. his gives us two advantages,
requiring expensive and bulky fluorescence microscopes to see the result. he electronics for our electrochemical readout can easily fit in a very small benchtop instrument,
The problem was that electron microscopes work by shooting electrons at the speed of light through a biological sample suspended in a vacuum;
and resolution was lost in the process. his combination of the bad detector, blurring from the motion and radiation damage,
and scientists at Lawrence Berkeley to build a new detector called the K2 Summit, named after one of the most challenging mountain ascents in the world.
society thirst for powerful sensors is growing. Given that, few sensing techniques can match the buzz created by surface-enhanced Raman spectroscopy (SERS.
researchers have assumed the mutations led to disease by altering the transport of proteins in and out of a cell nucleus. ow,
However, these approaches involve mechanical sensors and pumps, with needle-tipped catheters that have to be stuck under the skin
which involves shuttling tiny drops of water around on a series of small electrodes that looks like a miniature checkerboard.
#Major Step for Implantable Drug Delivery Device An implantable, microchip-based device may soon replace the injections
Earlier this month, MIT spinout Microchips Biotech partnered with a pharmaceutical giant to commercialize its wirelessly controlled, implantable,
microchip-based devices that store and release drugs inside the body over many years. Invented by Microchips Biotech cofounders Michael Cima, the David H. Koch Professor of Engineering,
and Robert Langer, the David H. Koch Institute Professor, the microchips consist of hundreds of pinhead-sized reservoirs,
each capped with a metal membrane, that store tiny doses of therapeutics or chemicals. An electric current delivered by the device removes the membrane,
and osteoporosis. Now Microchips Biotech will begin co-developing microchips with Teva Pharmaceutical, the world largest producer of generic drugs,
Apart from providing convenience, Microchips Biotech said these microchips could also improve medication-prescription adherence a surprisingly costly issue in the United states. A 2012 report published in the Annals of Internal medicine estimated that Americans who don stick to prescriptions rack up $100 billion
Microchips Biotech will continue work on its flagship product, a birth-control microchip, backed by the Bill and Melinda Gates Foundation,
Cima, who now serves on the Microchips Biotech board of directors with Langer, sees this hormone-releasing microchip as one of the first implantable rtificial organsbecause it acts as a gland. lot of the therapies are trying to chemically trick the endocrine systems Cima said. e are doing that with this artificial organ we created.
Wild ideas Inspiration for the microchips came in the late 1990s, when Langer watched a documentary on mass-producing microchips. thought to myself,
ouldn this be a great way to make a drug-delivery system??Langer said. He brought this idea to Cima,
a chip-making expert who was taken aback by its novelty. ut being out-of-this-world is not something that needs to stop anybody at MIT,
Cima adds. n fact, that should be the criterion. So in 1999, Langer, Cima, and then-graduate student John Santini Phd 9 co-founded Microchips,
and invented a prototype for their microchip that was described in a paper published that year in Nature.
This entrepreneurial collaboration was the first of many for Cima and Langer over the next decade.
For years, the technology underwent rigorous research and development at Microchips Biotech. But in 2011, Langer and Cima,
and researchers from Microchips, conducted the microchipsfirst human trials to treat osteoporosis this time with wireless capabilities.
In that study, published in a 2012 issue of Science Translational Medicine, microchips were implanted into seven elderly women,
Results indicated that the chips delivered doses comparable to injections and did so more consistently with no adverse side effects.
That study, combined with ongoing efforts in contraceptive-delivery microchips, led Cima to believe the microchips could someday,
essentially, be considered the first artificial glands that could regulate potent hormones inside the body. This may sound like a wild idea but Cima doesn think so.
The chip ends an endocrine or chemical signal instead of an electrical signal. MEMS innovations Microchips Biotech made several innovations in the microelectromechanical systems (MEMS) manufacturing process to ensure the microchips could be commercialized.
A major innovation was enabling final assembly of the microchips at room temperature with hermetic seals. Any intense heat during final assembly, with hermetic sealing, could destroy the drugs already loaded into the reservoirs
which meant common methods of welding and soldering were off-limits. To do so, Microchips Biotech modified a cold-welding ongue and grooveprocess.
This meant depositing a soft, gold alloy in patterns on the top of the chip to create tongues, and grooves on the base.
By pressing the top and base pieces together, the tongues fit into the grooves, and plastically deforms to weld the metal together. ach one of these reservoirs,
The company has also found ways to integrate electronics into the microchips to shrink down the device.
the company could refine the microchips to be even smaller, yet carry the same volume of drugs. his means making the drugs take up more volume than the electrical and other components,
providing the detection of both copy number variations (CNVS) and loss of heterozygosity (LOH) on a single chip.
researchers at MIT unveil a series of sensors, memory switches, and circuits that can be encoded in the common human gut bacterium Bacteroides thetaiotaomicron.
we built four sensors that can be encoded in the bacterium DNA that respond to a signal to switch genes on and off inside B. thetaiotaomicron,
the drug led to abnormal development of microchambers, including decreased size, problems with muscle contraction and lower beat rates compared with heart tissue that had not been exposed to thalidomide. e chose drug cardiac developmental toxicity screening to demonstrate a clinically relevant application of the cardiac microchambers,
and other UC Berkeley researchers publicly debuted a system of beating human heart cells on a chip that could be used to screen for drug toxicity.
However, that heart-on-a-chip device used pre-differentiated cardiac cells to mimic adult-like tissue structure.
In the mathematical model, the theoretical robot was equipped with sensors and a miniature microscope to measure the color of bacteria telling it where
She taps the phone's screen in a certain pattern, records a spoken phrase and walks a short distance while the phone's motion sensors measure her gait."
or using the iphone's built-in sensors to measure their symptoms. Scientists overseeing the studies say the apps could transform medical research by helping them collect information more frequently and from more people, across larger and more diverse regions,
researchers also say a smartphone's microphone, motion sensors and touchscreen can take precise readings that,
in some cases, may be more reliable than a doctor's observations. These can be correlated with other health or fitness data and even environmental conditions, such as smog levels, based on the phone's GPS locater.
each of the subjects put on an electrode-studded hat capable of analysing their brain signals. They then instructed the robot to move,
By virtue of its video camera, screen and wheels, the robot, located in an EPFL laboratory, was able to film itself as it moved
or relax, meaning the hand can operate without the bulky and cumbersome electronics that often make artificial prosthetic hands impractical.
illuminates the ELISA plate with an array of light-emitting diodes. The light projects through each well and is collected by 96 individual plastic optical fibers in the attachment.
including labs-on-a-chip. The transition temperature can be controlled by varying the chemical composition of the hydrogel. y locally heating
In the laboratory, the Spectinomycin analogs have blocked the growth of pneumococcal bacteria strains which are resistant to commonly used antibiotics.
a sensor comprising multiple tiny test sites. The chip, known as proteo, functions by attracting a faintly luminous substance found in cancer patients,
even when the cancer is at a very early stage.""We diagnosed without any errors
Nanette Byrnes, writer for the MIT Technology Review, calls this the ew food economy. y combining this information with data generated by soil sensors and weather reports,
Such investments led to the creation of water sensors and drones which help farmers, like Keith Larrabee, make effective decisions.
hen Larrabee began using such sensors, he had to walk into the fields to read each one individually process so laborious that he sometimes did it just once a week.
But now, every 15 minutes, readings from the 25 sensors are fed into a network of solar-powered information-gathering stations scattered through the orchard.
If your thermostat or air conditioning unit is constantly turned on, it would be fighting the ZEF table
what it will be like to use the iphone as a remote control for your entire home (AAPL) The first home appliances that will work with Homekit, Apple's platform for connecting all of the devices in your home,
#Scientists made a major breakthrough in 3d printed electronics that will keep you from ever drinking spoiled milk again Researchers have used 3d printing to develop a sensor that can be placed inside a carton of milk to detect
This represents a breakthrough in terms of three dimensional printing of electronic circuits. Polymers are poor conductors of electricity
whereas flat plates made for useful capacitors. The basis of this led to the production of the sensor cap for milk cartons.
The sensor functioned by detecting an increase in level of electrical signal as would be accompanied by a growth in bacterial population.
When this occurs a signal can be sent wirelessly. Sung-Yueh Wuuc Berkeley engineers created a mart capusing 3d printed plastic with embedded electronics to wirelessly monitor the freshness of milk.
The sensor was tested on various cartons of milk, some held at room temperature and some in a refrigerator.
It was found that the cartons kept at room temperature produced the electrical signal far earlier
"The study was conducted at UC Berkeley (the Berkeley Sensor and Actuator Center) together with Taiwan's National Chiao tung University.
The research has been published in the journal Microsystems & Nanoengineering, in an article headed"3d printed microelectronics for integrated circuitry and passive wireless sensors. e
For the last two years, Amal Graafstra, the founder and CEO of the Seattle-based company, has sold implantable devices including near-field communication (NFC) chips, radio-frequency identification chips (RFID), biomagnets,
His chips enable him to do things like lock and unlock doors and log into his computer and password-secured websites.
The US Food and Drug Administration (FDA) approved RFID chips for human implantation in 2004.
The team outfitted the animals with multi-electrode arrays in the motor and somatosensory (sense of touch) cortices to capture
or components, including Apple, Microsoft, Sony, Intel and Samsung. Location-based services have been billed as a convenient way to target information to people, such as shoppers,
So far, the Wi-fi Aware technology has been incorporated into a wireless chips from Broadcom, Intel, Marvell and Realtek."
That strategy takes advantage of new-generation cars as rolling collections of sensors to reduce congestion
and parking sensors, "will have only modest impacts.""Cities, with Moscow one of the leaders, have been testing
and sensors to speed up the parking once they get there. In congested downtowns, drivers looking for parking account for up to a third of the automobile traffic.
She taps the phone's screen in a certain pattern, records a spoken phrase and walks a short distance while the phone's motion sensors measure her gait."
or using the iphone's built-in sensors to measure their symptoms. Scientists overseeing the studies say the apps could transform medical research by helping them collect information more frequently and from more people, across larger and more diverse regions,
researchers also say a smartphone's microphone, motion sensors and touchscreen can take precise readings that,
in some cases, may be more reliable than a doctor's observations. These can be correlated with other health or fitness data and even environmental conditions, such as smog levels, based on the phone's GPS locater.
You can get all the details from the research team article, owards Scalable Binderless Electrodes: Carbon Coated Silicon Nanofiber Paper via Mg Reduction of Electrospun Sio2 Nanofibers, published in Nature Scientific Reports.
Solar, software and storage are making distributed energy possible in the same way that semiconductors,
Some lithium-ion batteries with graphite anodes provide less than 600 Wh/L a thin sheet of lithium foil was used to replace the more conventional electrode material,
and you can produce enough electricity to turn on an LED light. If this seems like small potatoes,
#The Fossil fuel energy Industry Is Now Entering Terminal Decline It time to make the call fossil fuels are finished.
battery manufacturers, copper and lithium miners, electronics producers, software developers, electric engine makers, smart grid builders and, of course, solar and wind power manufacturers, installers and financiers.
Tech startup Aclima just announced a partnership with Google earth Outreach to equip Google street view cars with its mobile sensor platform.
Aclima Sensory Science system connects stationary sensors with scalable hardware and software to generate billions of data points across multiple environmental factors,
For several years, 500 connected Aclima sensors have been monitoring air quality and analyzing 500 million data points daily across a global network composed of 21 Google offices around the world.
Using Aclima science-driven sensor networks to map our indoor environmental quality is a big part of making that happen. a
#Flexible sensor lets humans detect magnetic fields The sensor on a soap bubble. IFW Dresden When it comes to navigating the world around us we have a lot more than just five senses.
or external sensor--such as a new device developed by a team of researchers from the Leibniz Institute for Solid State
The sensor is less than 2 micrometres thick and only weighs 3 grams per square metre --so light they can be laid on a soap bubble without breaking it.
The sensors are...imperceptible magneto-sensitive skin that enables proximity detection navigation and touchless control the paper's abstract reads.
The sensor on the palm of a hand (left) and crumpled into a tiny ball (right) IFW Dresden These ultra-thin magnetic field sensors readily conform to ubiquitous objects including human skin
and offer a new sense for soft robotics safety and healthcare monitoring consumer electronics and electronic skin devices.
At the moment the sensors don't provide tactile feedback to the user. Instead they are connected to an array of LEDS.
When the wearer moves the sensor close to a magnetic field the sensor is shown to be operational when the LED array lights up.
Although this might be a bit unwieldy for everyday human use it could be ideal for robotics.
The integration of magnetoelectronics with ultrathin functional elements such as solar cells light-emitting diodes transistors as well as temperature and tactile sensor arrays will enable autonomous and versatile smart systems with a multitude of sensing
and actuation features the team concluded. They hope their work will inspire a diverse number of devices that will benefit from a'sixth sense'magnetoception.
as well as developing the technique to etch other materials, such as superconductors and dielectrics for the development of water-repellent electronics s
while the electrodes a new composite made of silicon and platinum microbeads can be pulled in any direction.
These conduction tracks and electrodes convey electrical current to the spinal cord much as the brain does.
where they lit up more than 300 LED streetlights at two different sites. Their plant power technology is also being used to power the company headquarters in Wageningen.
By providing an electrode for the microorganisms to donate their electrons to the electrons can be harvested as electricity.
The pacemaker has a sensor that detects when food is entering the stomach. It then fires low-level electrical pulses into the vagus nerve to fool the brain into thinking the stomach has no more room.
and the shell housing the tiny electronics, which then pass harmlessly out of the body as waste.
The system includes headphones and a lollipop-like device that sits on your tongue and stimulates it in time with a relaxing mixture of music and nature sounds,
which is played through earphones connected to a signal generator the size of a mobile phone. Clinical trial results suggest it can reduce tinnitus loudness by an average of about 40 per cent.
and creates a mild current to stimulate nerves in sync with the sound played through the earphones.
and the real sound being played into the headphones. In a trial at the National University of Ireland, the system was tested on 60 people who'd had tinnitus for longer than six months.
#The HEADPHONES that detect brain damage: Pioneering device tracks changes in pressure caused by injury and infection Doctors have developed a brain pressure test using a special set of headphones that can detect life-threatening head injuries and infections.
The technique involves a patient wearing the headphones with an ear plug linked to a computer.
This enables doctors to measure fluid pressure in the skull-known as intracranial pressure (ICP)- without the need for surgery or painful spinal procedures.
The headphones are set to be used in the diagnosis and treatment of conditions such as meningitis and head trauma injuries
'However, as our CCFP device does not require a patient to do anything other than wear a set of headphones with an ear plug,
when worn with a pair of Samsung 3d glasses, could magnify scenes by 2. 8 times. The lens-glasses combination was designed to help restore the sight of people suffering from age-related macular degeneration, or blindness.
When the lenses are being worn in'ordinary mode'this magnified image is blocked by polarising filters fitted to a pair of modified Samsung 3d glasses.
Google is also working on'smart lenses'that contain a control circuit, an image capture component and an image sensor.
000 A Japanese electronics firm is selling a 13ft (four metre) mechanical suit on Amazon that can be controlled by an iphone,
When the suit's microphones pick up ultrasonic reflections from objects, the arms respond by pressing down on the wearer's body
when worn with a pair of Samsung 3d glasses, can magnify scenes by 2. 8 times. The contact lenses are 8mm in diameter,
The Emotive headsets are embedded with sensors that record electrical activity along the wearer scalp, forehead and above the right ear.
These sensors measure and monitor brain waves and these patterns are converted to commands using a brain-computer interface.
'The new air vehicle could be used to transport sensors, equipment or weaponry in the future, depending upon how the technology develops.
It reached Mach 4. 8 in less than half a minute powered by a solid rocket booster.
After separating from the booster, the scramjet engine was ignited, accelerating the aircraft to Mach 5. 1 at 60,000 feet.
however, they cannot play music through a device like regular earphones, and are intended instead only to engage'with real world sound.'
'Here is meant not to replace your headphones, headsets, or earbuds,'the company said.''The Here Active Listening System is designed for live listening environments,
uses'Heat Pipe'technology to direct heat away from LEDS to stop them becoming dimmer and less efficient over time.
despite LEDS being invented originally to last a lifetime. His gripe with conventional lights is that they fail to protect LEDS from heat,
exposing them to temperatures up to 130°C (266°F) and damaging the phosphorous coating, meaning LEDS produce worse quality light over time.
To solve this problem, he has designed CSYS task lights that have unique technology in order to direct heat away from their LEDS. perating at 55°C (131°F),
they don lose quality or efficiency for 37 years, according to his website. Speaking in a video, Dyson said his greatest innovation to date is the ability to cool LEDS
which he said are ompletely critical to the LED market. e said the LEDS are hidden in conical cones,
which produce an even spread of light, so they are highly efficient without using diffusers.
The LEDS use a fifth of the energy of a conventional halogen bulb and because there are few bulbs to replace in a lifetime,
used scanning electron microscopes to examine eight dinosaur fossils. These included a claw from a predatory theropod and bones from several unidentified hadrosaurs.
and hardy nail polish where chips are repaired automatically. The research, carried out at the University of Bristol,
#Samsung's smart MIRROR shows weather, traffic information and even Facebook notifications as you brush your teeth You could soon see traffic delays as you take your morning shower,
or catch up with what's been happening on Twitter as you get dressed thanks to Samsung's latest display technology.
and Transparent OLED display panels initially designed to create a'virtual necklace'for a jewellery firm.
'Samsung has a long legacy of leadership in technology innovation for digital signage, as well as for other applications,
and Transparent OLED display solutions,'said Samsung. The technology consists of a 55-inch mirror fitted with a transparent OLED on the front.
It is fitted with Intel's Real Sense technology, which uses 3d cameras to track the viewer and display clothes and other items virtually,
Together, Samsung said the technology creates a'virtual fitting room'that will be used to help people see themselves wearing clothes
A spokeman added that the Samsung Mirror Display may also replace home mirrors in the future, showing digital information to homeowners in the same space where they now just have a traditional mirror.
but Samsung said its Mirror OLED display panel has more than 75 per cent reflectance level and delivers at least 50 per cent higher reflectance than rival models.
compared to eight milliseconds on LCD transparent panels. Samsung's Mirror Display technology also does need not the ambient backlight for displaying on-screen images that LCD technology does.
Elsewhere, Samsung's Transparent Display uses Real Sense 3d-rotatable viewing systems, with full HD video playback.
These displays could be used to show adverts, public and transport information or be used in hotels and shops.
'We are excited very to help bring a new interactive dimension to the world of multi-channel shopping through the integration of our newest OLED displays with Intel Realsense technology,
'said Oseung Yang, vice president, Samsung Display Company y
#Holus, Star wars-style'holobox',creates virtual 3d worlds and makes holo calls By Sarah Griffiths for Mailonline Published:
and a Pro version with an HDMI port and SDK tool so developers to use other devices with the Holus and come up with new uses for it.
Elsewhere, it is possible to connect the device to an Emotiv Brain Sensor to control holographic objects with your mind,
acting as a filament, to metal electrodes. When they passed a current through it the graphene lit up.
500°C but does not melt the electrodes because the'hot spot'is restricted to the centre of the filament.
By directing high-frequency microwaves towards a target, it is theoretically possibly to destroy unprotected electronics.
The gun would use a'reflector antenna'to focus the microwaves created by a generator.
so it unclear exactly how the weapon would work. he new system is equipped with a high-power relativistic generator and reflector antenna, management and control system,
enabling rapid iteration and development of space related technologies. neweb plan involves 20 groups of low-orbiting satellites being connected to small terminals on the ground that would act as hubs to link to phones and computers.
whether the antenna technology used on the satellites will be able to deliver high-speed Internet to the ground without hiccups. r Musk has said previously that he expects his service to handle 10 per cent of all Internet traffic
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