#X-rays and electrons join forces to map catalytic reactions in real-time: New technique combines electron microscopy and synchrotron X-rays to track chemical reactions under real operating conditions A team of scientists used a newly developed reaction chamber to combine x-ray absorption spectroscopy and electron microscopy for an unprecedented portrait of a common chemical reaction.
The results demonstrate a powerful operando technique--from the Latin for"in working condition"--that may revolutionize research on catalysts, batteries, fuel cells,
and other major energy technologies.""We tracked the dynamic transformations of a working catalyst, including single atoms and larger structures,
during an active reaction at room temperature,"said study coauthor and Brookhaven Lab scientist Eric Stach."
"This gives us unparalleled insight into nanoparticle structure and would be impossible to achieve without combining two complementary operando techniques."
To prove the efficacy of this new mosquito-sized reaction chamber--called a micro-reactor--the scientists tracked the performance of a platinum catalyst during the conversion of ethylene to ethane, a model reaction relevant to many industrial synthesis processes.
They conducted x-ray studies at the National Synchrotron Light source (NSLS) and electron microscopy at the Center for Functional Nanomaterials (CFN), both DOE Office of Science User Facilities."
and distribution of catalysts affect their efficiency and durability,"said study coauthor Ralph Nuzzo of the University of Illinois at Urbana-Champaign."
"Now that we can track those parameters throughout the reaction sequence, we can better determine the ideal design of future catalysts--especially those that drive energy-efficient reactions without using expensive and rare materials like platinum."
"Hidden behind the curtain In transmission electron microscopy (TEM), a focused electron beam passes through the sample and captures images of the nanoparticles within.
This is usually performed in a pristine environment--often an inactive, low-pressure vacuum--but the micro-reactor allowed the TEM to operate in the presence of an atmosphere of reactive gases."
"With TEM, we take high-resolution pictures of the particles to directly see their size and distribution,"said Stach,
who leads CFN's Electron microscopy Group.""But with the micro-reactor, some signals were too small to detect.
Particles smaller than a single nanometer were hidden behind what we call the resolution curtain of the technique."
"Another technique was needed to peer behind the curtain and reveal the full reaction story: x-ray absorption spectroscopy (XAS.
In XAS, a beam of x-rays bombards the catalyst sample and deposits energy as it passes through the micro-reactor.
The sample then emits secondary x-rays, which are measured to identify its chemical composition--in this instance, the distribution of platinum particles."
"The XAS and TEM data, analyzed together, let us calculate the numbers and average sizes of not one,
but several different types of catalysts,"said coauthor and Yeshiva University scientist Anatoly Frenkel, who led the x-ray experiments."
"Versatile micro-reactor The new micro-reactor was designed specifically and built to work seamlessly with both synchrotron x-rays and electron microscopes."
"Everything was controlled exquisitely at both NSLS and CFN, including precise measurements of the progress of the catalytic reaction,
"For the first time, the operando approach was used to correlate data obtained by different techniques at the same stages of the reaction."
"A relatively straightforward mathematical approach allowed them to deduce the total number of ultra-small particles missing in the TEM data."
"We took the full XAS data, which incorporates particles of all sizes, and removed the TEM results covering particles larger than one nanometer--the remainder fills in that crucial subnanometer gap in our knowledge of catalyst size
and distribution during each step of the reaction, "Frenkel said. Added Stach,"In the past, scientists would look at data before and after the reaction under model conditions, especially with TEM,
and make educated guesses. Now we can make definitive statements.""Brighter, faster experiments The collaboration has extended already this operando micro-reactor approach to incorporate two additional techniques--infrared
and Raman spectroscopy--and plans to introduce other complex and complementary x-ray and electron probe techniques over time.
"Each round of data collection took six hours at NSLS, but will take just minutes at NSLS-II,
"Through Laboratory Directed Research and development funding, we will be part of the initial experiments at the Submicron Resolution X-ray (SRX) Spectroscopy beamline this summer,
but other new micro-reactors can operate at up to 800 degrees Celsius--more than hot enough for most catalytic reactions
In the near future, this same micro-reactor approach will be used to explore other crucial energy frontiers,
including batteries and fuel cells.""We are seeing the emergence of a very powerful and versatile technique that leverages both NSLS-II
who was named recently Special Assistant for Operando Experimentation for Brookhaven's Energy Sciences Directorate.""This approach complements the many facilities being developed at Brookhaven Lab for operando energy research.
Our goal is to be world leaders in operando science."#"##About Brookhaven National Laboratory Brookhaven National Laboratory is supported by the Office of Science of the U s. Department of energy.
For more information, please visit science. energy. gov. One of ten national laboratories overseen and primarily funded by the Office of Science of the U s. Department of energy (DOE), Brookhaven National Laboratory conducts research in the physical, biomedical, and environmental sciences,
as well as in energy technologies and national security. Brookhaven Lab also builds and operates major scientific facilities available to university, industry and government researchers.
Brookhaven is operated and managed for DOE's Office of Science by Brookhaven Science Associates, a limited-liability company founded by the Research Foundation for the State university of New york on behalf of Stony Brook University, the largest academic user of Laboratory facilities,
and Battelle, a nonprofit applied science and technology organization n
#The Hydrogen fuel cell will revolutionize the economy of the world: New non-platinum and nanosized catalyst for polymer electrolyte fuel cell Abstract:
Canadelectrochim have discovered a new non-platinum and nano-sized catalyst for the fuel cell based on Mother Nature
which mimics the plant leaf. PEMFC as an optimal solution for the future energy economypolymer electrolyte membrane or proton exchange membrane fuel cell (PEMFC), where chemical energy is converted directly to electrical energy,
provides a highly efficient alternative to a standard internal combustion engine. High power density, clean emissions (water), low temperature operation, rapid start-up and shutdown,
and ability to use fuels from renewable sources are several reason why fuel cells such as PEMFC have attracted attention for large market applications,
such as transportation. With these unique features, PEMFC will revolutionize the future energy economy. Modern applications for PEMFCPEMFC will indirectly make water our future fuel.
Hydrogen and oxygen generated by splitting water using photosynthesis can be used as a fuel for PEMFC.
PEMFC are leading candidates to power the space shuttle and other mobile applications even down to mobile phones,
however, there are still some important issues that must be resolved in order for PEMFC to be commercially competitive.
It is known that splitting a hydrogen molecule at the anode of fuel cell using platinum is relatively easy.
Unfortunately however splitting the oxygen molecule at the cathode of fuel cell (oxygen reduction reaction(,ORR)) is more difficult
and this causes significant polarization losses (lowers efficiency of the fuel cell). An appropriate catalyst for this process has not been discovered
and as of yet platinum is the best option. Platinum as the best element for use of PEMFCPLATINUM is by far the most effective element used for PEMFC
in order to represent a realistic alternative to internal combustion engines (1, 2). Fuel cells generate electricity by combining hydrogen gas with oxygen to produce water (figure 1). Although that sounds perfectly clean and green,
that hydrogen is generated typically by"reforming"fuels such as natural gas, gasoline, or ethanol, which invariably introduces carbon monoxide into the hydrogen gas.
it can poison the platinum catalysts that are important to driving the fuel cell. In the heart of a fuel cell, CO binds tightly to platinum
and prevents it from grabbing hydrogen, the first step in the reaction.)However, Hydrogen produced from water splitting by photosynthesis is very clean
An electrolyte or membrane is used to separate oxygen gas at the cathode region from hydrogen gas in the anodic region,
while ions can still migrate from the anode to the cathode. The electrolyte plays a key role.
It must permit only the appropriate ions to pass between the anode and cathode. If free electrons or other substances could travel through the electrolyte,
they would short circuit the current in the fuel cell and fuel cell degradation occurs. Advancements in the electrolyte system of PEMFCTHE commercial development of a special electrolyte (single ion conducting polymer electrolyte) changed the field of electrochemical devices in a significant way.
Electrochemists have spent many years in a continuing search for newer, more highly conducting (ions and not electrons) and a more electrochemically stable electrolyte system.
With the development of a single ion (for example only hydrogen ions in PEMFC) conducting polymer, electrochemists have the ability to choose from a variety of polymers with both high conductivity for a given ion of interest (off course hydrogen ions
in PEMFC) as well as excellent stability and process-ability allowing the design of electrochemical devices (such as PEMFC) in their most ideal format (3). The broad class of electrolyte (electrolyte is a polymer
and so it is called polymer electrolyte) to which Nafion (discovered by Dupont company) belong has application in a number of area of commercial importance,
not limited to PEMFC. When the PEMFC reaches its eventual position as the major power generation system in a broad-based application such as automotive propulsion,
these Nafion electrolytes will reach a scale of production far exceeding the current levels. This change will bring about significant challenges for companies who manufacture the electrolyte but also offer tremendous opportunity.
It is likely that these future ubiquitous electrolytes for PEMFC will look different, produce much less pollution during manufacturing
and cost much less than the electrolyte that dominate the commercial landscape today. Optimizing PEMFC and positive environmental impactsfuture PEMFC will have to use low grade (inexpensive) hydrogen gas
which contains impurities (e g. carbon monoxide) that poison precious metal catalysts (e g. platinum) only at low temperatures (less than 120°C)
and reduces the PEMFC efficiency and power output. In addition to mitigating catalyst poisoning there are a number of advantages to operating the PEMFC at higher temperature and lower humidity,
such as increasing catalytic activity, reducing cathode flooding and eliminating the need for external humidification equipment. However, at higher temperatures, current electrolyte that is used in PEMFC dehydrate (becomes very dry),
reducing ionic conductivity (no hydrogen ions would be able to migrate) and overall cell performance. This is because optimal operation for current PEMFC is 80 C
and 100%relative humidity because Nafion is used as an electrolyte in these PEMFC. Thus there is a worldwide effort currently underway to find suitable alternatives to Nafion that might allow higher temperature operation
and be more cost effective. In the direction of operating the fuel cell using a cost effective and non-platinum based catalyst,
is the work of Canadelectrochim, based on Mother Nature idea. Mother Nature can build very efficient catalysts.
Environmental mechanisms sourced from Canadelectrochimcanadelectrochim is a small Research and development company located in Calgary, Alberta had presented a mechanism for the fuel cell reaction based on Mother Nature
which mimics the plant leaf. This research work was presented in the 2011 and 2012 IMRC meeting in Cancun
Mexico. This work was based on the idea that rain droplets are known to roll or bounce on the surface of plant leaves,
removing dust particles and contamination. This self-cleansing action is due to the presence of a special surface layer
which is composed of microscale poles. Each of these microscale poles is covered with billions of nanoscale poles.
In physics it is called Heterogeneous superhydrophobic surface. Based on the idea that has been called hierarchical roughness, a mechanism for the oxygen reduction reaction can be explained easily.
Based on this mechanism the reaction of the fuel cell does not require platinum. References 1 Hydrogen
Fuel cells & Infrastructure Technologies Program Multi-Year Research, Development and Demonstration Plan, U s. Department of energy, October 2007.2 Hydrogen fuel Cells & Infrastructure Technologies Program Multi
-Year Research, Development and Demonstration Plan, U s. Department of energy, October 2007.3 M. Doyle and G. Rajendran, Chapter 10, Handbook of fuel cell, edited by W. Vielstich, Volume 3:
Fuel cell technology and Applications, John Wiley Ltd. 2003)##For more information, please click herecontacts: M. Redaphone:
4034673552writeemail('gmail. com','mreda14';'Copyright Canadelectrochimissuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark: News and information June 29th, 2015efforts to Use Smart Nanocarriers to Cure Leukemia Yield Promising Results June 29th, 2015making new materials with micro-explosions:
ANU media release: Scientists have made exotic new materials by creating laser-induced micro-explosions in silicon,
the common computer chip material June 29th, 2015x-rays and electrons join forces to map catalytic reactions in real-time:
New technique combines electron microscopy and synchrotron X-rays to track chemical reactions under real operating conditions June 29th,
2015chemistry X-rays and electrons join forces to map catalytic reactions in real-time: New technique combines electron microscopy and synchrotron X-rays to track chemical reactions under real operating conditions June 29th,
2015green Chemistry Methods Used in Iran to Produce Zinc oxide nanoparticles June 27th, 2015laser spectroscopy: A novel microscope for nanosystems June 25th, 2015iranian Researchers Synthesize Nanostructures with Controlled Shape, Structure June 25th, 2015discoveries June 29th, 2015efforts to Use Smart Nanocarriers to Cure Leukemia Yield
Promising Results June 29th, 2015making new materials with micro-explosions: ANU media release: Scientists have made exotic new materials by creating laser-induced micro-explosions in silicon,
the common computer chip material June 29th, 2015x-rays and electrons join forces to map catalytic reactions in real-time:
New technique combines electron microscopy and synchrotron X-rays to track chemical reactions under real operating conditions June 29th, 2015announcements June 29th, 2015efforts to Use Smart Nanocarriers to Cure Leukemia Yield Promising
the common computer chip material June 29th, 2015x-rays and electrons join forces to map catalytic reactions in real-time:
the common computer chip material June 29th, 2015x-rays and electrons join forces to map catalytic reactions in real-time:
Updates to the Basis of the Company's Industry-Changing Nanotechnology Designed to Strengthen Position in Global Air, Energy,
and Water Markets June 26th, 2015artificial Intelligence An important step in artificial intelligence: Researchers in UCSB's Department of Electrical and Computer engineering are seeking to make computer brains smarter by making them more like our own May 11th, 2015making robots more human April 29th, 2015lifeboat Foundation launches Interactive Friendly AI April 6th,
2015nanotubes self-organize and wiggle: Evolution of a nonequilibrium system demonstrates MEPP February 10th, 2015fuel Cells X-rays and electrons join forces to map catalytic reactions in real-time:
New technique combines electron microscopy and synchrotron X-rays to track chemical reactions under real operating conditions June 29th, 2015buckle up for fast ionic conduction June 16th, 2015a protective shield for sensitive catalysts:
Hydrogels block harmful oxygen June 15th, 2015nist's'nano-raspberries'could bear fruit in fuel cells June 9th, 201 2
#Measurement of Tiny Amounts of Heavy metals in Baby Food Samples Abstract: Iranian researchers produced a nanosorbent that can adsorb
and measure small amounts of heavy metals in children food samples. The nanosorbent has speed high and accuracy and can be produced through a cost-effective method.
and measurement of heavy metals in foodstuff and environmental samples to reduce and eliminate the chemical harms caused by metals.
Detection and measurement of cadmium is very important among all different metals. In addition, although small amounts of zinc is necessary to the body
its high concentration causes digestive malfunctions and results in the related diseases due to its toxicity.
Therefore, the researchers focused on the detection of these metals, specially in foodstuff that are complicated very in terms of measurement.
Magnetic organometallic framework (MOF) nanocomposite has been used to selectively separate these metals from the foodstuff and their pre-concentration.
MOFS are porous solid phases that contain pores in which some of the metallic ions are placed.
and measure heavy metals. Among the most important advantages of this nanosorbent, mention can be made of reducing the cost of food sample evaluation,
reducing pollution caused by large consumption of toxic solvents due to the high surface area, and high sorption capacity.
Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content. Bookmark: News and information Samsung's New Graphene technology Will Double Life Of Your Lithium-Ion Battery July 1st,
2015nei Announces the Issuance of Multiple Patents on Self-Healing & Superhydrophobic Coatings June 30th, 2015philips Introduces Quantum dot TV with Color IQ Technology from QD Vision:
Manufacturer is first to offer quantum dot displays for both TVS and monitors June 30th, 2015carnegie Mellon chemists characterize 3-D macroporous hydrogels:
Methods will allow researchers to develop new'smart'materials June 30th, 2015discoveries Chitosan coated, chemotherapy packed nanoparticles may target cancer stem cells June 30th,
2015graphene flexes its electronic muscles: Rice-led researchers calculate electrical properties of carbon cones, other shapes June 30th,
2015researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th,
2015visible Light-sensitive Photocatalysts Used for Purification of Contaminated water in Iran June 30th, 2015announcements Samsung's New Graphene technology Will Double Life Of Your Lithium-Ion Battery July 1st,
2015researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th,
2015oxford Instruments Tritonxl Cryofree dilution refrigerator selected for the Oxford NQIT Quantum Technology Hub project June 30th,
2015visible Light-sensitive Photocatalysts Used for Purification of Contaminated water in Iran June 30th, 2015interviews/Book reviews/Essays/Reports/Podcasts/Journals/White papers Samsung's New Graphene technology Will Double Life Of Your Lithium-Ion Battery July 1st,
2015graphene flexes its electronic muscles: Rice-led researchers calculate electrical properties of carbon cones, other shapes June 30th,
2015researchers from the UCA, key players in a pioneering study that may explain the origin of several digestive diseases June 30th,
2015visible Light-sensitive Photocatalysts Used for Purification of Contaminated water in Iran June 30th, 2015food/Agriculture/Supplements Bacteria Cellulose,
Natural Polymers with Applications in Various Industries Synthesized in Iran June 22nd, 2015high-tech nanofibres could help nutrients in food hit the spot June 17th, 2015the European project SVARNISH,
a step forward in the food packaging sector June 11th, 2015tissue Engineering Scaffolds Produced from Natural Silk in Iran June 8th,
201 0
#Leti Announces Launch of First European Nanomedicine Characterisation Laboratory: Project Combines Expertise of 9 Partners in 8 Countries to Foster Nanomedicine Innovation and Facilitate Regulatory Approval CEA-Leti today announced the launch of the European Nano-Characterisation Laboratory (EU
-NCL) funded by the European union Horizon 2020 research and innovation programm 1 e. Its main objective is to reach a level of international excellence in nanomedicine characterisation for medical indications like cancer, diabetes, inflammatory diseases or infections,
and make it accessible to all organisations developing candidate nanomedicines prior to their submission to regulatory agencies to get the approval for clinical trials and, later,
marketing authorization. s reported in the ETPN White paper 2, there is a lack of infrastructure to support nanotechnology-based innovation in healthcare,
said Patrick Boisseau, head of business development in nanomedicine at CEA-Leti and chairman of the European Technology Platform Nanomedicine (ETPN).
anocharacterisation is the first bottleneck encountered by companies developing nanotherapeutics. The EU-NCL project is of most importance for the nanomedicine community,
as it will contribute to the competiveness of nanomedicine products and tools and facilitate regulation in Europe.
EU-NCL is partnered with the sole international reference facility, the Nanotechnology Characterization Lab of the National Cancer Institute in the U s. US-NCL) 3,
to get faster international harmonization of analytical protocols. e are excited to be part of this cooperative arrangement between Europe
and the U s.,said Scott E. Mcneil, director of U s. NCL. e hope this collaboration will help standardize regulatory requirements for clinical evaluation and marketing of nanomedicines internationally.
This venture holds great promise for using nanotechnologies to overcome cancer and other major diseases around the world.
EU-NCL is connected also closely to national medicine agencies and the European Medicines Agency to continuously adapt its analytical services to requests of regulators.
EU-NCL is designed, organized and operated according to the highest EU regulatory and quality standards. This project is important for Europe,
as it will be the first transnational infrastructure in nanomedicine. It aims at fostering innovation by sharing knowledge and technologies between academia and industry.
The mission of EU-NCL is: To provide a trans-disciplinary testing infrastructure covering a comprehensive set of preclinical characterisation assays (physical, chemical,
in-vitro and in vivo biological testing), allowing researchers to fully comprehend the biodistribution, metabolism, pharmacokinetics, safety profiles and immunological effects of their medicinal nanoproducts.
To foster the use and deployment of standard operating procedures (SOPS), benchmark materials and quality management for the preclinical characterisation of medicinal nanoproducts.
To promote intersectoral and interdisciplinary communication among key drivers of innovation, especially between developers and regulatory agencies.
This project, led by CEA-Tech (Leti and Liten, FR), brings together nine partners from eight countries:
Joint Research Centre-European commission (IT) European Research Services Gmbh (DE), Leidos Biomedical Research, Inc. U s.)Trinity college Dublin (IE) Stiftelsen SINTEF (NO) University of Liverpool
(UK) EMPA (CH) and Gesellschaft für Bioanalytik Münster (GE. Within EU-NCL, six analytical facilities will offer transnational access to their existing analytical services for public and private developers,
and will also develop new or improved analytical assays to keep EU-NCL at the cutting edge of nanomedicine characterisation.
with nearly 5 million euros allocated. 1 This project has received funding from the European union Horizon 2020 research
*The technology was designed to track the machinery of biological cells, down to the tiniest bits of DNA, a single"base pair"of nucleotides among the 3 billion of these chemical units in human genes.
But the instrument could be useful well beyond biology, biochemistry and biophysics, perhaps in manufacturing.
JILA is a partnership of the National Institute of Standards and Technology (NIST) and the University of Colorado Boulder."
"This technology can actively stabilize two items relative to each other with a precision well below one nanometer at room temperature,
"This level of 3d stability may start to interest the nanomanufacturing world, when they look at making
and characterizing things on the single-nanometer scale.""The work builds on JILA's world-leading expertise in measuring positions of microscopic objects.
The latest tweaks extend stability for a much longer time period, many hours at a time. With the longer observation times, researchers can see more successive steps of molecular motors, for instance.
These biochemical processes are responsible for a broad range of movement in living organisms, including moving molecules around the interior of a cell or copying DNA into another form of genetic material, RNA.
The new JILA instrument also can aid in measuring individual proteins as they fold into specific positions
The instrument must be stable to within about one-tenth of a nanometer (1 angstrom to biologists, equivalent to the diameter of a hydrogen atom.
it can reliably achieve tenth of a nanometer stability for up to 100 seconds at a time. And it can do this over and over again for extended periods--the JILA team operated the system for up to 28 hours straight.
"This technology excites me because it opens the door to measuring the tiniest protein motions,
#New Biosensor Produced in Iran to Detect Effective Drugs in Cancer Treatment Iranian researchers designed a biosensor with application in assessment of effectiveness of drugs on the stability of the four-strand structure of DNA to prevent the growth
Gold nanoparticles have been used in the production of the biosensor. The four-strand structure of DNA plays an important role in the process of creation of cancerous cells and in the prohibition of a type of active enzyme in cancers.
Therefore it is very important to study the stability of this structure on biosensors and to create a simple method to investigate their interactions with a number of drugs and compounds.
The studies can be used in the diagnosis, designing and production of anticancer drugs. The research team presented an effective method to detect the four-strand structure of DNA by using biosensors.
Electrochemical studies showed that the designed biosensor creates an appropriate environment for the evaluation of the drug abilities to stabilize the structure.
In this research, printing graphite electrode modified with silica and gold nanoparticles was used as an appropriate bed for the production of biosensors to detect four-strand structure of DNA
and to study its interaction with a number of drugs s
#Miniature Technology, Large-scale Impact: Winner of the 2015 Lindros Award for translational medicine, Kjeld Janssen is pushing the boundaries of the emerging lab-on-a-chip technology The postage stamp-sized square of fused silica Kjeld Janssen is holding
may not look like a whole lot to the untrained eye, but inside the clear chip lies the potential to improve how medicine
and medical research is done. f you can integrate and automate an analysis technique into a chip,
it opens doors to great applications, said Janssen, a postdoctoral researcher in the Sumita Pennathur Lab at UC Santa barbara. With only a minimal amount of human plasma,
the Omnisense nanofluidic chip he is developing is the heart of a device that can assist in the swift and accurate diagnosis of bacterial
or viral infection in less time than it would take conventional tests and it would cost less as well.
The portability of the technology could be used to enable clinical services and quick on-site screening,
particularly in remote areas where people don have access to a full medical lab, as well as data gathering for clinical trials or epidemiological studies.
For the impact his project will have in the field of translational medicine the postdoctoral scholar has been awarded the 2015 Lindros Award from the UCSB Translational Medical Research Laboratory (TMRL.
t very awesome, Janssen, a recent transplant from The netherlands, said of the award. It feels like a recognition of his effort,
including late-night and after-hours work, and of his students which is especially gratifying and motivating,
he added. The $10, 000 grant provided by the award will be used in direct support of the development of the Omnisense lab-on-a-chip. he promise and delivery of high-throughput, real-time,
multiplexable detection of viruses and bacteria is one of the most sought-after technologies and methodologies in all of medicine, said Dr. Scott Hammond,
executive director of TMRL. orking with the Pennathur Lab, Kjeld Janssen research is intended to bring real-time detection to the world of medicine.
This technology, said Hammond, allows for the identification of specific DNA markers in an advanced microfluidic device. urther,
so compelling is this research that UCSF, as a part of their partnership with the TMRL, is directly collaborating on this project
in order to provide human physiological samples and access to their world-leading standard of practice, he said.
Janssen, who received his doctoral degree from Leiden University, is no stranger to the sensing of the very small.
As part of his work getting his master degree which he received from the University of Nijmegen in The netherlands he did internships in the country and in France on detecting neurotransmitter secretion from single neurons.
For his postdoctoral work, he studied the downscaling of bioanalytical techniques to the nanoscale, taking
what would normally require tubes or vials of plasma down to technology that would require less than a single drop.
He worked more than two years in industry, developing lab-on-a-chip technology for Medimate B. V, . before crossing the Atlantic to land in Pennathur lab. At UCSB,
Janssen focus is currently on developing a nucleic acid amplification test on a chip, technology that could, in real time,
sense for DNA-based markers in human samples. According to him, the analysis technique to be used in the nanofluidic chip loop-mediated isothermal amplification is suited particularly well for a low-cost device he has planned for this technology. t simple,
he said, explaining that the chip would need less energy and that obtaining results would require fewer steps than other methods.
The benefits in this technology could lead to its deployment of this technology in remote areas of the world and in developing countries,
where the local health care infrastructure might not be able to support the level of research
or medicine necessary to monitor or treat patients. Efforts to study and combat highly infectious diseases,
including Hepatitis C, SARS or MERS, could also benefit from the user friendly chip and its rapid results. is award is truly helping our lab become translational,
said UCSB mechanical engineering professor Sumita Pennathur. t a big step forward in terms of bringing out nanofluidic technology to real biomedical applications of disease diagnosis
. I'm so excited for him!
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