New substrate opens door to mass produced regenerative therapies Mass produced regenerative therapies are a step closer say UK researchers who have developed a polymer substrate they claim can be used to set up tem cell factories.
The polymer which is called poly (HPHMA-co-HEMA)- combines N-(4-hydroxyphenyl) methacrylamide and 2-hydroxyethyl methacrylate.
and neural progenitors. he idea is coated culture vessels with the polymer are arranged into arrays or factories each capable of supporting the production of billions of human pluripotent stem cells for applications in regenerative medicine and transplants.
the Nottingham team also claim their polymer could help regenerative medicines developers reduce manufacturing costs. Substrates a substantial costsubstrates used for commercial stem cell production are expensive.
We are testing the substrate with potential commercial partners now. ommercial applicationsthe polymer has application in both the production of cells for drug safety testing
Advanced Materialsiscovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multi-lineage Differentiationoi:
generally using a technique known as X-ray crystallography. But this method relies on getting proteins to pack tightly together to form uniform crystals,
which is notoriously difficult, especially when it comes to the floppy, dynamic proteins that live in cell membranes.
and to do so without first having to form crystals. Revisualizing a Classic Technique Known as single-particle cryo-electron microscopy
"These are extremely difficult targets for X-ray crystallography, and I anticipate that CRYO EM will also play a significant role in this area."
and Suhua Jiang, associate professor of materials science, and Zhejun Liu, Ph d. candidate, both at Fudan University in China.
the process can excite vibrational modes of these molecules and produce inelastic scattering, also called Raman scattering, of light.
While rich in details, the signal from scattering is weak and difficult to read without a very powerful laser.
and a dielectric layer of silica or alumina. The dielectric separates the mirror with tiny metal nanoparticles randomly spaced at the top of the substrate. t acts similar to a skeleton key.
and plastically deforms to weld the metal together. ach one of these reservoirs, until you open it,
the UCLA and City of Hope researchers attached sirna to the outside of a particular type of nanoparticle developed by Zink called mesoporous silica nanoparticles.
Zink said the advance would be possible because of the structure of the specific type of nanoparticles the researchers are using. esoporous silica nanoparticles contain thousands of pores
who also is distinguished a UCLA professor of chemistry and biochemistry and a pioneer in the design and synthesis of multifunctional mesoporous silica nanoparticles u
and how fast to go depending upon the pigment and intensity of color. The model also revealed higher order functions in a surprising way.
iscovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation. he possibilities for regenerative medicine are still being reached in the form of clinical trials,
Previous research has evaluated the use of microneedles made of silicon or metal but they were shown not to be safe.
The lightweight plastic hand itself was designed and 3d printed by a research team from Saarland University.
known as shape-memory alloy, has the highest energy density of all known actuation mechanisms, which allows it to perform powerful movements in restricted spaces s
Georgia Institute of technology Study Coating the inside of glass microtubes with a polymer hydrogel material dramatically alters the way capillary forces draw water into the tiny structures,
the liquid begins to flow into the tube, pulled by a combination of surface tension in the liquid and adhesion between the liquid and the walls of the tube.
while the polymer layer locally deforms. The meniscus then rapidly slides for a short distance before the process repeats.
After using high-resolution optical visualization to study the meniscus propagation while the polymer swelled, the researchers realized they could put this previously-unknown behavior to good use.
or cooling the polymer inside a microfluidic chamber, you can either speed up the filling process
That would allow precise control of fluid flow on demand using external stimuli to change polymer film behavior.
dynamically evolving polymer interfaces in which the system creates an energy barrier to further motion through elasto-capillary deformation,
the paper authors wrote. his insight has implications for optimal design of microfluidic and lab-on-a-chip devices based on stimuli-responsive smart polymers.
the research team included Professor Vladimir Tsukruk from the Georgia Tech School of Materials science and engineering and Rajesh Naik, Biotechnology Lead and Tech Advisor of the Nanostructured and Biological Materials Branch
and tag individual cells using fluorescent polystyrene beads of different diameters, rather than injected droplets of oil or fat.
Ribo-T may be able to be tuned to produce unique and functional polymers for exploring ribosome functions
or producing designer therapeutics--and perhaps one day even non-biological polymers. No one has developed ever something of this nature."
Polymers are poor conductors of electricity and 3d printing is based primarily around a set range of plastics.
To overcome this, Controlled Environments reports that the research group designed materials based around polymers and wax.
This created hollow tubes suitable for the addition of a liquid metal. For initial studies, silver was used to fill the tubes via nano-injection.
Various experiments found the shape and design of the material affected how it performed and its suitability in different applications.
Sung-Yueh Wuuc Berkeley engineers created a mart capusing 3d printed plastic with embedded electronics to wirelessly monitor the freshness of milk.
The Shanghai Composite rose over 150%between mid-2014 and its peak in Mid-june 2015.
he and his colleagues found the brain was much more plastic than they had thought. Scientists said that with practice,
Secondly, if this water gets to the steel reinforcementsn concrete we have all these steel rebarsf they corrode, the structure collapses.
and calcium lactate into capsules made from biodegradable plastic and adding the capsules to the wet concrete mix.
As a living plant, reeds absorb silica from soil, and the silica accumulates around cellulose microcompartments.
Therefore, reeds are suitable natural reservoirs of nano-structured silica and its derivatives. Yet they are not only appropriate Si sources,
they also contain silica in a very favorable nanoscale arrangement. reed leaves exhibit well-defined sheetlike 3d hierarchical micro-structures,
which as we demonstrate can be transformed into a well-suited 3d highly porous hierarchical Si architectures. he topological architecture of the original silicates within the reed leaves is preserved extraordinarily well during the applied chemical and physical treatment steps.
and Lawrence Livermore National Laboratory employed a microfluidic assembly technique to produce microcapsules that contain liquid sorbents encased in highly permeable polymer shells.
Aines says that the MECS-based approach can also be tailored to industrial processes like steel and cement production significant greenhouse gas sources.
These permeable silicone beads could be sliced a-bread'breakthrough for CO2 capture--efficient easy-to-handle minimal waste
which the flow rates of three fluids--a carbonate solution combined with a catalyst for enhanced CO2 absorption a photocurable silicone that forms the capsule shell
while the electrodes a new composite made of silicon and platinum microbeads can be pulled in any direction.
a long cone made from a composite of fiberglass and carbon fibre is designed to vibrate in the wind, according to a report in Wired.
The silicone-tipped earbuds are inserted into then ear and their audio features can be controlled using a smartphone app.
hollow microspheres to carbon fibre composite materials. These break on impact, releasing a liquid healing agent that seeps into the cracks left by the damage.
when researchers at the University of Illinois in the US created a plastic that could repair itself
The University of Illinois team created a polymer in 2014 that they showed can fix holes of up to three centimetres.
Its incredible properties include being 200 times stronger than steel by weight, conducting electricity and being nearly transparent.
Such an ultrathin display can be applied to flexible materials like plastics and synthetic fabrics. The research has major implications for existing electronics like televisions,
It can be inflated in less than one second by pulling a metal lever and triggering the CO2 cylinder to fill the balloon,
but the company say they will be ready to lay down the first plastic roads within three years.
19 inch (48 cm) forged alloy DIN hp: 477 Price: from £59, 995 ($93, 337)' We saw firsthand that
New alloy has highest melting point of any known metal at 4, 126°C a new material with a higher melting point than any other known substance has been invented by scientists.
The exotic alloy, which is a combination of the rare metal hafnium, carbon and nitrogen, would only begin to melt into a liquid at temperatures of more than 4, 126°C (7,
460°F)- two thirds the temperature of the surface of the sun. The extreme melting point makes the metal a candidate for creating a real-life version of adamantium the almost indestructible fictional metal used to make Wolverine's claws in the X-men
comics. Scientists develop the new material using computer simulations to calculate the optimal composition that would give the material its record breaking melting point.
The researchers are now hoping to synthesise the material and to test its properties in the laboratory.
'Until the scientists have synthesised successfully the new alloy and tested its melting point, the record for highest melting point will remain with a substance made using hafnium, tantalum and carbon (Hf-N-c),
which melts at a temperature 3, 526°C. The researchers calculated the formula for the new alloy (Hf-N-c) by simulating the physical processes that occur at the atomic level when a substance melts.
They started by analysing the properties of the Hf-Ta-C material and then looked for compounds that might maximise those further.
They found Hf-Ta-C combined a high heat of fusion the energy absorbed or released when it transforms from solid to liquid and low differences in disorder of the atoms,
or entropy, as a solid or liquid. Most metals require high temperatures to melt because they have stable molecular structures that require a lot of energy to break.
The behaviour of the atoms as a liquid also determines this melting point. They found their Hf-N-c alloy would absorb similar amounts of energy
when it melted but had a smaller difference between the in the entropy between a solid and liquid.
They worked out its melting point would be 474°C higher than Hf-Ta-C. Professor van de Walle and Dr Qijun Hong,
who also took part in the research, say their research could help develop new types of heat shields on spacecraft
Melting point isn't the only property that's important in material applications.''You would need to consider things like mechanical properties and oxidation resistance and all sorts of other properties.'
'So taking those things into account you may want to mix other things with this that might lower the melting point.'
with no sewing required. the printer works with custom polyester and cotton blends, that are shipped as liquids in pods that are placed into the machine prior to each job. the team consists of marcus foley, aaron rowley both biomedical/mechanical engineers and joseph white,
and phone-less independence. made of zinc aluminum alloy, the lock incorporates the most advanced fingerprint sensor from sweden. it utilizes a radio frequency signal to scan the pattern under the surface of the skin to guarantee its authenticity. the body is has no keyholes to deny any idea of lock picking,
that when heated above its melting point, reacts with the acid, and shifts to its colored form. each roll of paper has 85 feet of paper to print. compact and easy to use,
over the uneven metal layers. his is had why we to find a means of filling in
whose electronic properties are similar to those of metals, black arsenic phosphorus behaves like a semiconductor.
According to the researchers, the graphene film has a thermal conductivity capacity that is four times that of copper. Significantly the team has developed a graphene film that can be attached to silicon substrates.
The researchers have shown that the in-plane thermal conductivity of the graphene-based film, with 20 micrometer thickness, can reach a thermal conductivity value of 1600 W/mk,
which is four times that of copper. A likely application says Johan Liu is the integration of graphene-based film into LEDS, lasers and radio frequency components for cooling purposes. s
whose electronic properties are similar to those of metals, black arsenic phosphorus behaves like a semiconductor.
According to the researchers, the graphene film has a thermal conductivity capacity that is four times that of copper. Significantly the team has developed a graphene film that can be attached to silicon substrates.
The researchers have shown that the in-plane thermal conductivity of the graphene-based film, with 20 micrometer thickness, can reach a thermal conductivity value of 1600 W/mk,
which is four times that of copper. A likely application says Johan Liu is the integration of graphene-based film into LEDS, lasers and radio frequency components for cooling purposes n
Made from recycled plastic, it features a solar panel in the flap which charges as the children walk to and from school as well as strips of reflective material,
Google also talked up the concept of giving new and unusual battery designs a forum to experiment with Project Ara there are battery technologies that offer substantial improvements over conventional lithium polymer architectures
which is why a new announcement from Fuji Pigment is so interesting. The company is claiming that its new aluminum-air batteries can run for up to two weeks
Fuji Pigment new announcement makes repeated reference to the work of Ryohei Mori, and while the referenced papers aren available for free,
Periodically, the aluminum anode will have to be replaced it not clear how often the Fuji Pigment battery would need servicing of this sort.
Fuji Pigment has stated that it intends to commercialize this technology as early as this year,
not only how to build precisely defined bandgaps into composites of graphene and boron nitride, but they have uncovered also the deeper electronic structure of the material
What the MIT researchers basically did was take single layers of hexagonal graphene and stack them up against single layers of hexagonal boron nitride.
In contrast to the unidirectional current flow of electrons in a regular metal, a material that behaves as a opological insulatorwould be useful in several spintronic applications.
electrons in graphene composites configured with just the right alignment can flow at significantly greater speeds,
The main trick behind the scheme is to preload the chamber of a hypodermic needle with a series of magnetizable steel balls and spacers.
Neodymium permanent magnets have a lower magnetic saturation (at only 77%that of steel they can only produce 43%of the equivalent magnetic force of steel),
On the other hand, with steel electromagnets, the force goes away when you turn off the electromagnet. If you were to introduce permanent magnets into the body, by eating them for example,
The authors note that the maximum gradient available in most clinical scanners is in around 20-40mt/m. This would produce a force on a magnetized steel particle equal to 36-71%of its gravitational force.
and cytoskeletal protein composites that should be expected to behave nonlinearly with regards to impacts. In other words like a pool surface, impact speed should greatly affect the material stiffness that is felt by a penetrating object.
In reference to these, the device uses electrophoresis to attract charged color particles to the top transparent electrode to preadtheir color,
and a polymer solution on top of an indium-tin-oxide (ITO) glass ply that was used as the anode for the LED.
After the 1-octyne solution was removed and the silicon quantum dots solidified they were submerged then in either 1) 2-propanol
Quantum dots are nanocrystals that emit light when xcitedbased on their size, and, when implemented in QLED TVS,
and deforming permanently due to plastic buckling. Elastic buckling honeycomb structures provide the materials needed so that a given item could stretch
the team of researchers created hygroscopy-driven artificial muscles (HYDRAS) that exhibit strong hydration-driven actuation.
The material is made from plastic tape coated with a micrometer-thick bacterial spore layer. This layer is formed with modified Bacillus subtilis spores,
University of Nebraska-Lincoln chemist Xiao Cheng Zeng found that the computer model predicted the crystals were incredibly conductive,
and has a thermal conductivity capacity that is four times that of copper. A team led by professor Johan Liu from Chalmers University had shown earlier that graphene can have a cooling effect on silicon-based electronics
Moreover, functionalisation using this kind of bonding doubles the thermal conductivity of the graphene. ncreased thermal capacity could lead to several new applications for graphene.
The researchers said the effect could be explained by the lower boiling point of water at high altitude
Sous-vide which involves vacuum sealing the food in plastic pouches and immersing them in a water bath at 65-85°C and cook-vide in
Alice Mougin Olivier Mauroux Walter Matthey-Doret Eugenia Maria Barcos Fernand Beaud Ahmed Bousbaine Florian Viton and Candice Smarrito-Menozz i
Professor Wass explains. arbon fiber composites have been used widely in Formula one and performance cars for many years,
which uses carbon fibre composites could benefit, Professor Wass notes. t the consumer end of the market that could be sports equipment, bike frames, and so on.
which uses flexible mobile devices made with Lycra or alloy displays. These can bend, stretch and change shape automatically.
According to the reports, the laser is prepared with the simulated atoms, notably known as quantum dots. The study is published in the Science journal.
The study was begun to investigate the quantum dots, and not lasers. Quantum dots act like single atoms
as segments for quantum computers. An associate professor of physics, Jason Petta at Princeton and the lead author of the study,
The analyst included that they were intrigued at first by investigating the use of quantum dots together. That implies two quantum dots joined together as quantum bits or qubits.
Qubits are the basic unit of data in quantum computing. e composed dots to emanate photons
These dual quantum dots are zero-dimensional as far as the electrons are concerned they are caught in each of the three spatial dimensions
Due to its high powered processing capabilities the technology can acquire the scan through aluminum plastic
#Researchers developed hydrophobic metals using laser Engineers have spent decades studying super-hydrophobic surfaces because of the plethora of real-life applications.
Researchers from the University of Rochester have developed a method to make metals hydrophobic or waterproof when they are treated with lasers.
with application opportunities not only in the brain but in other parts of the nervous system and other organs as well, says the study other co-principal investigator, John A. Rogers, professor of materials science and engineering at the University of Illinois. For now,
Mirkin is professor of chemistry in the Weinberg College of Arts and Sciences and professor of medicine, chemical and biological engineering, biomedical engineering and materials science and engineering.
researchers have been searching for polymers on which human pluripotent stem cells can be grown and differentiated in vast numbersillions at a time. he possibilities for regenerative medicine are still being researched in the form of clinical trials,
Working with the expertise of chemical engineering and materials science researchers at MIT, the researchers developed an approach based on ellular backpacks?
#How lasers make metal super water repellent Scientists have used lasers to turn metals into extremely water repellent materials without the need for temporary coatings.
-and nanoscale structures to give the metals their new properties. This work builds on earlier research by the team in which they used a similar laser-patterning technique that turned metals black.
Guo says that with this technique, they can create multifunctional surfaces that are not only super-hydrophobic but also highly-absorbent optically.
Guo adds that one of the big advantages of his team process is that he structures created by our laser on the metals are intrinsically part of the material surface.
And it is these patterns that make the metals repel water. he material is so strongly water-repellent,
Unlike Guo laser-treated metals, the Teflon kitchen tools are not super-hydrophobic. The difference is that to make water to roll off a Teflon coated material,
You can make water roll off Guo metals by tilting them less than five degrees. As the water bounces off the super-hydrophobic surfaces
but ultra-short laser pulses to change the surface of the metals. A femtosecond laser pulse lasts on the order of a quadrillionth of a second
MULTIFUNCTIONAL METALS Guo is keen to stress that this same technique can give rise to multifunctional metals.
Metals are naturally excellent reflectors of light. That why they appear to have a shiny luster.
The combination of light-absorbing properties with making metals water repellent could lead to more efficient solar absorbersolar absorbers that don rust
#Hybrid crystals fuse semiconductors and metal Tomorrow's computers and electronics will require extremely small high-quality circuits.
and metal the material has a special superconducting property at very low temperatures. The superconductor in this case is aluminium.
The atoms sit in a perfectly ordered lattice in the nanowire crystal not only in the semiconductor and the metal but also in the transition between the two very different components which is significant in itself explains Peter Krogstrup an assistant professor who helped develop the contact.
Krogstrup says it is the ultimate limit to how perfect a transition one could imagine between a nanowire crystal and a contact.
which are made polymers from natural materials like proteins or from human-made substances to make plastic,
rubber or fiber, including biodegradable materials. The new method, dubbed"magnetospinning, "provides a simple, scalable,
Ph d.,study co-author and the Georgia Power Professor of Polymers, Fibers and Textiles in UGA's college of family and consumer sciences."
"Currently, the most common nanofiber manufacturing technique, called electrospinning, uses high-voltage electricity and specially designed equipment to produce the polymer strings.
Polymer that has been melted or liquefied in a solution is mixed with biocompatible iron oxide or another magnetic material and placed inside a hypodermic needle.
This needle is positioned then near a magnet that is fixed atop a spinning circular platter. As the magnet passes by the tip of the needle,
a droplet of the polymer fluid stretches out and attaches to the magnet, forming a nanofiber string that winds around the platter as it continues to spin.
"The researchers can use this method to create a variety of nanofibers simply by changing the polymer placed in the syringe.
"We can use almost any kind of polymer with this platform, and we can tailor make the nanofibers for different applications,
Previous research has evaluated the use of microneedles made of silicon or metal, but they were shown not to be safe.
"Using X-ray crystallography, the team determined the three-dimensional structure of TOPLESS, both on its own and when linked with other molecules responsible for turning genes off, thereby regulating gene expression.
Ribo-T may be able to be tuned to produce unique and functional polymers for exploring ribosome functions
and perhaps one day even non-biological polymers, point out Dr. Mankin.""We felt like there was a very small chance Ribo-T could work,
or the interaction between light and free electrons on a metal's surface. When exposed to light,
gold is a popular metal for plasmonic photothermal heating since it is extremely efficient at absorbing light.
According the company, the new piezoelectric polymer converts pressure and vibration into electric energy with high efficiency,
ceramics and polymers. Both are based on the principle of using mechanical strain to generate electricity
Ceramics convert vibration to energy with high efficiency, but theye heavy, fragile, and often include toxic lead,
while polymers are lighter, more flexible, and more durable, but not very efficient. According to Ricoh, its new energy-generating rubber combines flexibility and high energy output.
It's not only less fragile than ceramics, but it's also more flexible and durable than other polymers;
surviving several million uses in testing. In addition, it's sensitive to light loads, yet generates high output under heavier ones.
but it does say that it's engaged in further research to produce a commercially viable version of the polymer for both sensors and energy applications o
when EL panels made from plastic are bent too sharply, fractures and a severely diminished output usually result.
or plastic coated with a transparent conductive coating, while the opaque rear electrode is made generally from a reflective metal foil.
Gaseous isobutane is a sort of raw material for the petrochemical industry that can then be refined into a variety of plastics, fuels and other applications.
of which is a shape-memory nickel/titanium alloy. Women will then have scanned their feet using a portable in store device called the DOME.
It consists of rolls of adhesive wallpaper made of flexible polymer film, which is embedded with Kevlar fibers in a crisscross pattern.
and the scattering of the signal being reflected back to the receiving card when the person is not in the direct line of sight,
#3d printing breakthrough creates metal and copper structures The method developed at the University of Twente in The netherlands involves microscopic drops created from a thin metal film that is melted by a pulsed laser.
The key to this breakthrough in printing metals seems to be using a higher energy laser than in previous attempts.
creating drops of metal that maintained a more spherical shape and led to the creation of a stack that was less stable.
The team plans to look into this effect to improve printing capability not just in metals
Other efforts around the globe to print metals are also beginning to bear fruit, including hopes to exploit Australia's plentiful titanium reserves.
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