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and Neuroscience created mice lacking the gene for calcineurin in the forebrain; these mice displayed several behavioral symptoms of schizophrenia including impaired short-term memory attention deficits and abnormal social behavior.
Lancaster and her team could identify regions in the organoids that roughly looked like a hippocampus, forebrain and even retina.
Of the genetic associations found the largest effect was seen for the Putamen a subcortical region located at the base of the forebrain
Zhang and postdoctoral researcher Yuejun Chen attached brackets to a gene known to separate the midbrain from the forebrain, the site of higher mental functions.
they found that the gene is also essential to forming the forebrain. f you knock it out,
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