#PCR Makes the Jump to Light speed The amplification of minute amounts of genetic material is the cornerstone of every molecular biology laboratory
when EL panels made from plastic are bent too sharply, fractures and a severely diminished output usually result.
"said Doctor Ing. Rainer Kling, associate professor at the Light Technology Institute of KIT. Electroluminescent panels are a very popular way to backlight a screen,
advancing efforts to create blood for surgery and treat leukaemia and other cancers. His latest work continues in this same vein,
and make the main cell types of neurological systems-the central nervous system and the peripheral nervous system-in a dish that is specialized for each patient,
suggesting that they can be overpowered by the body's own system with help from a pioneering approach known as viral therapy.
but activate the body's own immune system to stave off harmful tumors. The clinical trial was conducted across 64 research centers around the world
and led by The Institute of Cancer Research in London. It saw 436 patients suffering from inoperable skin cancers treated with a modified form of herpes virus called Talimogene Laherparepvec T-VEC.
whose genetic errors give rise to weaker defences against infections. The result is engineered a genetically virus with the ability to grow in cancer cells and blow them up from the inside.
What's more, T-VEC is designed also to produce a molecule known as GM-CSF that moves the body's immune system to destroy tumors
Some of the 436 patients where treated with injections of T-VEC, while others were given a control immunotherapy.
when used in the less advanced stages of the cancer, suggesting that T-VEC could prove a valuable early treatment option for skin cancers that are unable to be removed by a surgeon.
Patients with stage III and early stage IV melanoma a condition that was shown to carry an average survival of 21.5 months
The scientists say that T-VEC is the first of such viral therapies to be proven beneficial in treating melanoma in a phase III clinical trial.
The drug has been submitted to both the US Federal Drug and Food administration and the European Medicines Agency for consideration, with the scientists hopeful of winning approval later this year.
The findings were published in the Journal of Clinical Oncology y
#Ballistic wallpaper to help protect soldiers seeking temporary shelter It sounds like an old Goon Show joke,
The fruit fly (or Drosophila) is one of the most important model organisms used in biomedical research it's easy to care for
and identification of these tiny beasts requires many monotonous human hours and anesthesia. This isn't always a good mix,
and avoiding anesthesia. Once restrained, the robot can identify the gender and physical characteristics of the fly and even prepare microdissections to analyze the brain.
Some also see potential for the portable paper power tech to create diagnostic tools for disease control in the developing world.
This involves a surgeon implanting electrical leads into the region of the brain that controls movement.
A pulse generator inserted under the skin below the collarbone provides electrical signals that create a lesion,
and not all patients qualify for the surgery. We asked if there was a way to provide the same treatment in a less invasive way that doesn't require brain surgery."
"From there, the students learned about an experimental clinical treatment called transcranial direct current stimulation, which involves low-level current being passed through electrodes on a patient's head.
Their prototype works for up to 20 minutes per day, with current delivered at a doctor-prescribed level.
with a likely additional feature being remote connectivity that allows a doctor to adjust a home patient's treatment levels from his or her office.
and areas such as rehabilitation therapy. This kind of technology also has obvious potential in industry, where constant heavy lifting is still very much a part of many working lives.
It also has knock-on effects for employers trying to retain workers, health care systems, and even the ability of countries to keep jobs from going abroad.
This unprecedentedly high graphene composition means that the oft-praised electric and mechanical properties of graphene might soon find their way into all kinds of macroscopic 3d printed creations, with important consequences for the electronics and biomedical fields (among many others.
according to the scientists involved, makes the objects printed with this ink highly flexible and safe for biomedical applications.
The ability to tune the elasticity of the material at will could prove important in manufacturing biomedical polymers that can,
paving the way for these materials to be used for biodegradable sensors and medical implants. But the applications of a highly-conductive graphene ink could be
#Elastic, wound-healing hydrogel activated by light Hydrogels have huge potential in the field of biomedicine,
sticking to the tissue at the site of injury and creating a barrier over a wound."
and had no toxic effects on living cells in the lab. The team also discovered that mixing the gel with silica nanoparticles gave it the ability to more effectively prevent bleeding,
something that could allow better protection of a wound and stop bleeding with a single treatment.
The scientists say that more preclinical studies are required to test the gel's properties and safety before human trials will be possible.
the hardware inside is starting to show huge promise in the world of medical diagnostics,
with smartphones repurposed as blood-scanning microscopes, HIV testers and sleep apnea detectors. The latest advance in this area comes in the form of a fiber optic sensor for smartphones that monitors bodily fluids,
a tool that could be used for biomolecular tests such as pregnancy or diabetes monitoring. Surface plasmon resonance (SPR) is a process where a stream of light is directed onto a metallic film, with most,
#Ultrasound cuts healing time of chronic wounds by 30 percent Further to the mental anguish, a lot of time in a hospital bed can bring about some agonizing physical discomfort.
This is most commonly brought about by skin ulcers and bedsores, which threaten to evolve into dangerous and potentially deadly infections if left untreated.
But a British research team has happened upon a technique that promises to cut the healing time of these
and other chronic wounds by around a third, using simple low-intensity ultrasounds. Wound healing presents a serious problem for two demographics in particular
the elderly and those with diabetes. When a young and healthy person incurs an injury to the skin,
connective tissue cells called fibroblasts migrate to the site of the wound and kickoff the healing process.
But skin defects that are typical of above groups prevent the migration of fibroblasts and make healing problematic, sometimes leading to amputation.
It found the technique reduced healing times by 30 percent in aged and diabetic mice,
The team also observed that the technique could be replicated successfully in human venous leg ulcer patients,
indicating that it could be applicable to other chronic human wounds. And because it is modelled on
#Smart capsule keeps hold of payload until reaching its target We have drugs to treat nasty conditions like irritable bowel syndrome and Crohn's disease,
a bacterial infection that causes the body to lose microorganisms essential in fighting off infection. One method used to treat C. difficile involves transplanting feces from another person into the large intestine to provide it with the missing microorganisms.
which could be used to improve night-vision technology, biomedical imaging, and high-speed telecommunications. The team next plan to build
It may one day be used to reverse acquired blindness, alter pain thresholds and even hit the rest button on our biological clocks.
"Now, we literally can deliver drug therapy with the press of a button, "says Jordan Mccall, a graduate student at Washington University in St louis and member of the research team."
The scientists say the technology could be used to one day treat pain, epilepsy, depression and other neurological disorders.
#Laser device may soon non-invasively monitor diabetics'glucose levels In order to monitor their blood glucose levels, diabetics typically have to perform painful and inconvenient finger-prick blood tests in some cases, several times a day.
Using an implantable glucose-monitoring sensor is one alternative, although it must be installed surgically and subsequently removed for replacement.
this technology opens up the potential for people with diabetes to receive continuous readings, meaning they are alerted instantly
or readings directly to doctors, allowing them to profile how a person is managing their diabetes over time."
#Pill on a string pulls early signs of cancer As with every form of the deadly disease,
early detection of oesophageal cancer is critical to recovery. The current approach of detecting the cancer through biopsy can be a little hit and miss,
so the University of Cambridge's Professor Rebecca Fitzgerald and her team have developed what they claim to be a more accurate tool for early-diagnosis. Billed as"a pill on a string,
"the Cytosponge is designed to scrape off cells from the length of the oesophagus as it is yanked out after swallowing,
According to Fitzgerald, the five-year survival rate for oesophageal cancer is only 13 percent, a fact
which has led researchers to hunt for signs of a condition that precedes the disease, known as Barrett's oesophagus.
Between one and five of every 100 people with Barrett's oesophagus go on to develop oesophageal cancer.
Using biopsies to detect the pre-cancer condition is problematic for a couple of reasons. It requires trained scientists to pore over the samples looking for abnormalities,
which introduces a degree of subjectivity and possible human error. And although a stretch of oesophagus affected by Barrett's could measure as much as 10 cm (4 in),
the biopsy may not really reveal much at all. So Fitzgerald and her team developed a solution they say can provide more accurate results.
With a string attached and in the nurse's hand, the sponge is pulled then up through the oesophagus.
"If youe taking a biopsy, this relies on your hitting the right spot, "says Fitzgerald."
"The researchers are hopeful the Cytosponge could replace expensive and invasive endoscopies. Already more than 2, 000 patients have swallowed the device in testing,
The team's latest research into Barrett's oesophagus and oesophageal cancer was published in the journal Nature Genetics.
#Mussel-inspired surgical glue shuts down bleeding wounds in 60 seconds The ability of mussels to stubbornly bind themselves to underwater surfaces has intrigued scientists for years.
A team of Korean scientists has developed now a surgical glue inspired by these natural wonders that's claimed to be cheaper,
In surgery, stitches and staples are very effective at binding body tissue together, but they can cause scarring
mussel protein-based adhesive (LAMBA) and claim to have proven its superiority to existing surgical glues.
the scientist say it was able to close bleeding wounds in less than 60 seconds and healed them without inflammation
#Age-related macular degeneration patient receives bionic eye transplant You might remember the Argus II implant from
Providing the implant works as intended, the patient will perceive patterns of light, which they can learn to interpret,
the implant received market approval from the Food and Drug Administration (FDA) in the US, for the treatment of Retinitis Pigmentosa (RP) a degenerative condition that affects the peripheries of patient vision.
The procedure was carried out at the Manchester Royal Eye Hospital in the United kingdom, by Dr. Paulo Strange MD.
Though this is only the first test using the implant for AMD sufferers, those initial positive results are extremely promising.
and to have the opportunity to help a great deal more people living with blindness, "says Second sight's Executive officer, Dr. Robert Greenberg."
#Needle-sized mechanical wrist gives surgery a new angle Some of the most difficult types of surgery just got easier and more versatile.
A team of engineers and doctors at Vanderbilt University has developed a tiny mechanical wrist that can be used for millimeter-sized incisions
Many larger surgical tools with flexible ends already exist, with designs that range from 2. 4 to 15 mm (0. 1 to 0. 6 in) in diameter,
While the mechanical wrist is expected to be useful in many different kinds of precise, small-scale surgery,
the researchers believe it will be particularly handy in needlescopic surgery (also known as micro-laparoscopy). This involves making incisions so tiny that they can be sealed with surgical tape and leave no scar behind.
Like laparoscopy, but on a smaller scale, it is accomplished using tiny surgical instruments that are fed through narrow tubes into the incision,
with a similarly tiny camera providing visual guidance. It's minimally-invasive surgery taken to the extreme.
Armed with the flexible mechanical wrist, surgeons will soon be able to conduct operations on this scale through natural orifices such as the nose
and throat and through the sharp corners encountered in other areas such as the ankle and middle ear.
the researchers plan to test the wrist in transnasal surgery. This kind of surgery normally involves cutting a big hole in a patient's skull
or face so that tumors can be removed from the pituitary gland and skull base. It can also be done through the nasal cavity with an endoscope (a thin tube with a camera attached),
but the procedure is extremely difficult. The mechanical wrist, they hope, will make this less-invasive alternative and many other kinds of operations less difficult,
"We think once we give this tool to surgeons, they will find all kinds of applications we haven't thought of,
and the software interface that allows surgeons to control the mechanical wrist should be completed by the end of August.
which was used to print the word"contaminated"on surgical gloves. When the gloves were exposed to E coli bacteria,
In addition to bio-sensing gloves that could react selectively to different pathological agents, Omenetto says the ability to print antibiotics in topographical patterns would enable"smart"bandages in
which therapeutics are incorporated custom into the bandage to match a specific injury. Additionally, although the researcher's tests only involved the use of one ink cartridge,
They expect the technology will enable more effective tools in the fields of therapeutics regenerative medicine and biosensing g
#Noninvasive spinal cord stimulation gets paralyzed legs moving voluntarily again Five men with complete motor paralysis have regained the ability to move their legs voluntarily
however, the researchers found success without performing any invasive surgery. The new treatment uses a technique called transcutaneous electrical nerve stimulation
and it is known to induce walking motions in mice with spinal cord injuries. All five men had been paralyzed for more than two years prior to receiving the treatment,
Edgerton now hopes to test the noninvasive stimulation on people with partial paralysis. He also notes that,
so that the physician and the patient can select a therapy that is best for them.""The study was conducted by researchers at UCLA, the University of California, San francisco,
National Institute of Biomedical Imaging and Bioengineerin r
#Earth's magnetic field may be more than 750 million years older than previously thought The Earth's magnetic field is crucial to life on the planet.
#World First Blood test To Diagnose Irritable bowel syndrome World First Blood test To Diagnose Irritable bowel syndrome Newshealthby Good News Network-May 21,
Two simple tests, developed by gastroenterologist Dr. Mark Pimentel of Cedars-Sinai Medical center in Los angeles,
finally gives doctors the ability to confirm whether a person actually has developed irritable bowel syndrome a common disorder that includes bouts of relentless diarrhoea,
which plagues about ten percent of the world population and nearly 40 million Americans. adsbygoogle=window. adsbygoogle.
push({}({}ost IBS patients have been told at one time or another that the disease was psychological, all in their head, said Dr Pimentel. he fact that we can now confirm the disease through their blood,
not their head, is going to end a lot of the emotional suffering I have seen these patients endure.
His nearly eight years of research centered around antibodies in the blood that had interacted previously with toxins during food poisoning.
WATCH the video below or READ more at Daily mail) Pass on the Good Newsbelow) TAGSBREAKTHROUGHHEALTHINNOVATIONMEDICALSCIENCEWELLNESS Cuban Cancer Vaccine Could Soon be Available in U s. May 20,
20150 Two Former Debt Collectors Want to Help Pay Your Medical bills May 18, 2015 i
#Asthma Could Be cured Within 5 Years With This New Breakthrough Asthma could be cured in five years
now that scientists have found the witchthat can turn off triggers that cause the condition in tens of millions of people worldwide.
and are used to treat people with osteoporosis. Researchers found that, when the drug is inhaled, it deactivates the cells and stops all symptoms.
to tackle the underlying causes of asthma symptoms, said Dr Samantha Walker, Director of research and Policy at Asthma UK. f this research proves successful we may be just a few years away from a new treatment.
Scientists are hopeful that patients can take the drug to prevent asthma attacks before they start ending the need to constantly carry an inhaler to end symptoms once an attack has started.
Walker added, ive percent of people with asthma don respond to current treatments, so research breakthroughs could be life-changing for hundreds of thousands of people.
The discovery could also lead to new treatments for chronic bronchitis or chronic obstructive pulmonary disease (COPD), a disease that kills tens of millions of people every year and for
which there currently is no cure. When Kids Can See the Chalkboard Eye doctor Donates 100,000 Glasses Researchers say
the treatment that could effectively cure asthma would be available in the next 5 years. The research, funded by Asthma UK, the Cardiff Partnership Fund,
and a Biotechnology and Biological sciences Research Council award, was published in the Science Translational Medicine journal in April.
WATCH the Cardiff University video below h
#For the first time, Artificial Feet Can Feel the Ground Scientists in Austria are taking their research on prosthetic limbs one step further by restoring the sense of touch to those who wear them.
Much of the worst quake damage and injuries in recent years result from older buildings collapsinghat because modern buildings in earthquake zones are designed with devices called dampers or isolation units,
#World First Malaria Vaccine Approved and it Will be Not-for-Profit The world first malaria vaccine has been given approval by a European medical agency for future use in Sub-saharan africa, where more than a quarter million children under the age of five die every year from the disease.
European regulators examined phase III clinical trial results involving more than 16,000 young children conducted by research centers in eight African countries (Burkina faso, Gabon, Ghana, Kenya, Malawi, Mozambique, Nigeria
Glaxosmithkline Vice president for Africa told CNN. t is the first time anyone ever has been able to make a vaccine against a parasite.
Perhaps most impressive, Glaxosmithkline, the pharmaceutical company that worked on this vaccine for 30 years, and received $200 million from the Gates Foundation, is making RTS, S available as a nonprofit drug.
with all that money going back into further research for a malaria vaccine that could be even more effective.
and expects to invest a further $200 to $250 million until the vaccine is ready for market.
With this approval from the European Medicines Agency Friday, the vaccine next will be considered by the World health organizations,
and if they will use the vaccine, along with current Malaria prevention techniques, like bed nets. 80%of the children involved in the clinical trials were protected also by insecticide treated bed nets.
RTS S, also known as Mosquirix, was administered to children aged 6 weeks to 17 months in three doses. Over the first 18 months following three doses of RTS, S,
malaria cases were reduced by almost half in children aged 5-17 months at the time of first vaccination and by 27%in infants aged 6-12 weeks.
At study end, over four years of follow-up in children RTS, S reduced malaria cases by 39,
In areas of the highest malaria burden, more than 6 000 clinical malaria cases were prevented over the study period for every 1, 000 children vaccinated
#Nest Thermostats Now Link Up to Products From LG Philips Whirlpool and Others Last June, Nest announced some big names in the first round of integration with its thermostat,
organic products that present little or no health risk. These molecules are also highly stable, even at fairly high temperatures,
and Response is aimed at 1. 6 million Medicare fee-for-service beneficiaries whose medical and assistive equipment oxygen concentrators, ventilators,
The integrated data can help hospitals, first responders and electric utility officials better plan to prevent adverse health impacts of prolonged power outages due to storms and natural disasters."
and EMS teams prepare for surges in medical services. Emergency planners could also use the map to anticipate
#Patient safety driving increased RFID use in hospitals The University of Vermont Medical center in Burlington, Vt.
Adam Buckley, MD, interim chief information officer and chief medical informatics officer at UVMC, said any time a system allows a hospital to track reliably from ordering through dispensing through administration at the bedside,
"We use a lot of kits in this hospital because our ORS are set up to have dispensed individual kits to the anesthesiologist for each case,
"she said.""We have hundreds of kits in addition we have kit-like trays in our code blue carts and on our resuscitation carts."
preparation and administration, said Kitcheck"has succeeded out of the gate"by applying RFID tags to anesthesia kits, already operational in over 100 hospitals.
what they refer to"critical inventory"used by hospitals high-cost medications in refrigerators and high-risk drugs in anesthesia kits and trays.
Aethon Inc.'s Medex tracking software links with its TUG robot that robotically transports items throughout hospitals
and track bullets throughout hospitals'pneumatic transport tubes with RFID. RFID vs. barcode Despite the progress RFID has made in the hospital setting, the debate over
a nurse could know via proximity reading that he or she has five medications in his hand,
According to Neuenschwander, the nurse would then need to move all five items out of the range of read
"RFID has materialized finally beyond prototypes to products that are live in hospitals today, "said Neuenschwander. UVMC's Buckley said that people are going to figure out the best way to leverage RFID technology."
#Hospital slashes false-positive diagnoses with CDS platform Children's Hospital of Pittsburgh of UPMC's electronic surveillance framework for hospitalized kids is poised to significantly reduce false-positive identification of serious health conditions.
This according to new peer-reviewed research published today in the journal Pediatric Critical Care Medicine.
The retrospective study of 16,239 Children's Hospital pediatric admissions between January 2006 and December 2013 compared the use of vital signs, a common indicator of patient condition, to that of Perahealth's Pediatric
mental state) to identify patients requiring urgent intervention with pediatric ICU transfer. The research, conducted by Children's Hospital clinicians,
"Many symptoms of serious pediatric conditions are also found in common conditions that do not require immediate intervention,
chief of pediatric critical care medicine at Children's Hospital of Pittsburgh of UPMC, said in a news release announcing the finding."
"Our research found the Pediatric Rothman Index to be a favorable electronic trigger for alerting clinicians to the need for rapid response teams,
complementing the efforts of our nurses and physicians.""Powered by the peer-reviewed Rothman Index,
a disease-agnostic universal score for predicting patient readmission and mortality risk, Perahealth software automatically pulls data from any major electronic health record in real-time.
The goal is to promote care team communication across shifts and alert clinicians earlier to unexpected health problems.
The Joint Commission estimates that 85 to 99 percent of alarms in hospitals do not require clinician intervention.
"False-positive alarms cause anxiety for care teams, patients and families, and can lead to clinicians becoming desensitized to true patient emergencies
and dsync+(TITECH/Georgia Tech) Near real-time plasma disruption detection using ADIOS (Princeton Plasma Research Lab/ORNL) Automated microscopy image analysis for cancer detection,
finding cures to Alzheimer and other diseases, developing new clean energy technologies, and promoting new advanced manufacturing opportunities.
such as disease fighting drugs from entering the nervous system. It only allows a selected few types of molecules to cross including water, some gases and lipid soluble molecules.
The scientists add that the method allows them to target multiple types of diseases by producing different carrier molecules.
The method is part of the NRC Therapeutics Beyond Brain Barriers (TBBB) program which has been developing special carrier molecules for the past six years. t really opens the possibilities to use many different types of therapeutics for different diseases that we couldn really use before
unless we inject them directly into the brain which is highly invasive, r. Danica Stanimirovic,
Scientists add that it could become a significant step towards slowing the spread of brain diseases like Alzheimer, multiple sclerosis and Parkinson.
Tough yet flexible, these spongy devices can withstand both shock and stress, a feature that many stretchable electronics do not possess.
#Spoken sentences can be reconstructed from brain activity patterns It is now possible to reconstruct spoken sentences from activity patterns of the human brain surface. rain to Textcombines knowledge from neuroscience, medicine and informatics.
our recent results indicate that both single units in terms of speech sounds as well as continuously spoken sentences can be recognized from brain activity. hese results were obtained by an interdisciplinary collaboration of researchers of informatics, neuroscience, and medicine.
The brain activity was recorded in the USA from 7 epileptic patients who participated voluntarily in the study during their clinical treatments.
An electrode array was placed on the surface of the cerebral cortex (electrocorticography (ECOG)) for their neurological treatment.
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