Synopsis: Domenii: Health: Health generale: Health policy:


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Nonetheless Poon says that is sufficient for this kind of low-power medical device. It also met safety regulations limiting the amount of radiation delivered to a given amount of tissue in humans.


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and measuring how it scatters off blood vessels (this is often done in hospitals with a device that fits over your fingertip).


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can big data make health care better? here is a lot of data being gathered. That not enough, says Ed Martin,

and the challenges they will face as they push to remake health care. The groups that control the most medical data today are insurance companies and care providers,

and their data analysis is already beginning to change health care. Express Scripts which manages pharmacy benefits for 90 million members in the U s


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That an interesting result with significant implications for government health policies. It shows that differences in culture affect the dynamics of social spreading processes in a measurable way.


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and hopes to sell them to manufacturers of wearable electronics, medical devices, smart labels, and environmental sensors.


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While gene drives may have commercial and public health uses, 10 scientists published an editorial today in the journal Science calling for more public discussion,


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Because all Britons are members of the National Health service, the project expects to be able to compare DNA data with detailed centralized health records (see hy the U k. Wants a Genomic National Health service.

While the number of genomes to be sequenced is 100 000, the total number of Britons participating in the study is smaller, about 70,000.


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Daniel Kopans, who founded the breast imaging division at Massachusetts General Hospital and developed tomosynthesis, says the latest evidence could push hospitals to move toward the new screening method. ltimately,

radiologists will recognize that if they miss a cancer because they weren using tomosynthesis, they could end up being sued by someone who said,

professor and chief of the breast imaging division at the Hospital of the University of Pennsylvania


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or DARPA, awarded two large contracts to Massachusetts General Hospital and the University of California, San francisco,

Companies including the medical device giant Medtronic and startup Cortera Neurotechnologies a spin out from UC Berkeley wireless laboratory,


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Bisognano a cardiologist who runs a resistant-hypertension clinic at the University of Rochester Medical center in New york knows well the need for more treatment options.


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says Lawrence Lustig, director of the Cochlear Implant Center at the University of California, San francisco Medical center.


the-scientist.com 2015 00007.txt

a microbiologist at New york University Langone Medical center who was involved not in the work. Although further studies are needed before the antibiotic can be tested in humans


timesofindia.indiatimes.com_home_science 2015 00356.txt.txt

These findings lead to the potential of moving from vaccines for specific influenza strains towards developing a protection,

"Our extraordinary breakthrough could lead to the development of a vaccine component that can protect against all new influenza viruses, with the potential for future development of a one-off universal flu vaccine shot,


timesofindia.indiatimes.com_home_science 2015 00416.txt.txt

Specialists at the NHS Royal Marsden Hospital and the Institute of Cancer Research (ICR) confirmed that melanoma skin cancer patients treated with a modified herpes virus (the virus that causes cold sores) had improved survival-a world first.

Specialists at the NHS Royal Marsden Hospital and the Institute of Cancer Research (ICR) confirmed that melanoma skin cancer patients treated with a modified herpes virus (the virus that causes cold sores) had improved survival-a world first.


timesofindia.indiatimes.com_home_science 2015 00441.txt.txt

so that the drug they make is slightly different than versions used in hospitals today. The process of creating erythromycin begins with three basic building blocks called metabolic precursors chemical compounds that are combined

so that the drug they make is slightly different than versions used in hospitals today. The process of creating erythromycin begins with three basic building blocks called metabolic precursors chemical compounds that are combined


timesofindia.indiatimes.com_home_science 2015 00457.txt.txt

#Tata doctors find way to cut oral cancer risk Tata Memorial Hospital, the cancer hub in Parel, announced a breakthrough on Tuesday that could

At a press conference held in the Parel hospital on Tuesday, one of the other investigators Dr Pankaj Chaturvedi said,


timesofindia.indiatimes.com_home_science 2015 00458.txt.txt

#Tata docs find way to cut oral cancer risk Tata Memorial Hospital, the cancer hub in Parel, announced a breakthrough on Tuesday that could

At a press conference held in the Parel hospital on Tuesday, one of the other investigators Dr Pankaj Chaturvedi said,


timesofindia.indiatimes.com_home_science 2015 00480.txt.txt

Stephen Elledge, an HHMI investigator at Brigham and Women's hospital and his colleagues have used already Virscan to screen the blood of 569 people in the US, South africa, Thailand, and Peru.

either through infection or through vaccination. The study was published in the journal Science e


timesofindia.indiatimes.com_home_science 2015 00487.txt.txt

#Now, aircraft wings that can'self heal'on the fly Even the researchers involved in the project describe it as"verging on science fiction".


timesofindia.indiatimes.com_home_science 2015 00524.txt.txt

The team has contacted hospitals in China about conducting human trials but has struggled to find volunteers,


timesofindia.indiatimes.com_home_science 2015 00571.txt.txt

#This vaccine could help block HIV WASHINGTON: Scientists have designed a new experimental HIV vaccine that may stimulate the immune system to block infection from the deadly virus. New research led by scientists at The Scripps Research Institute (TSRI),

INTERNATIONAL AIDS Vaccine Initiative (IAVI) and the Rockefeller University shows in mice that the vaccine candidate can stimulate the immune system activity necessary to stop HIV infection.

The findings could provide key information for the development of an effective AIDS vaccine, researchers said.

The research, published in the journals Cell and Science, represents a leap forward in the effort to develop a vaccine against HIV

which has struggled so far to elicit antibodies (immune system molecules) that can effectively fight off different strains of the virus."The results are said pretty spectacular

While many vaccines for other diseases use a dead or inactive version of the disease-causing microbe itself to trigger antibody production,

This challenge has led researchers to believe that a successful AIDS vaccine will need a series of related

"The vaccine appears to work well in our mouse model to'prime'the antibody response,


timesofindia.indiatimes.com_home_science 2015 00573.txt.txt

and heating to around fifty people living, for example, in a refugee camp or emergency hospital.

and heating to around fifty people living, for example, in a refugee camp or emergency hospital.


timesofindia.indiatimes.com_home_science 2015 00628.txt.txt

The UK's NHS (National Health service) Blood and Transplant has announced that manufactured blood will be used in clinical trials with human volunteers within two years.


timesofindia.indiatimes.com_home_science 2015 00841.txt.txt

while posing a greater threat to public health. The study is the first to demonstrate how leptospira mutates to form a biofilm, an extra protective layer of microbial cells,

The mutation study, published in a Federation of European Microbiological Studies journal in May, was a wake-up call for public health experts to find better ways to tame the bacteria.

or through cuts and abrasions,"said Dr Jayanti Shastri, head of microbiology at BYL Nair Hospital.

or vaccinating animals.""Till that happens, early diagnosis and prompt treatment is the key


timesofindia.indiatimes.com_home_science 2015 00874.txt.txt

#Vaccine success holds hope for end to deadly scourge of Ebola The world is for the first time on the verge of being able to protect humans against Ebola,

the World health organization (WHO) said on Friday, as data from a trial in Guinea showed a vaccine was 100 percent effective.

Initial results from the trial, which tested Merck and Newlink Genetics'VSV-ZEBOV vaccine on some 4, 000 people who had been in close contact with a confirmed Ebola case,

showed 100 percent protection after 10 days. The results were described as"remarkable"and"game changing"by global health specialists."

"We believe that the world is on the verge of an efficacious Ebola vaccine, "WHO vaccine expert Marie Paule Kieny told reporters in a briefing from Geneva.

The vaccine could now be used to help end the worst recorded outbreak of Ebola, which has killed more than 11,200 people in West Africa

since it began in December 2013. WHO Director-General Margaret Chan said the results, published online in the medical journal The Lancet,

"This and other vaccine trials were tracked fast with enormous international effort as researchers raced to be able to test potential therapies

and vaccines while the virus was still circulating.""We knew it was a race against time

"says John-Arne Rottingen, head of infectious disease control at the Norwegian Institute of Public health and chair of the trial's steering group."

"Ring vaccination"The Guinea trial began on March 23 to evaluate the effectiveness and safety of a single dose of VSV-ZEBOV using a so-called"ring vaccination"strategy,

where close contacts of a person diagnosed with Ebola are immunised-either immediately, or at a later date.

As data began to emerge showing the very high protection rates in those vaccinated immediately,

with all participants receiving the vaccine immediately, and will be extended to include 13-to 17-year-olds and possibly also 6-to 12-year-old children,

which allowed the team in Guinea to assess this vaccine in the middle of an epidemic"."""Our hope is that this vaccine will now help bring this epidemic to an end

and be available for the inevitable future Ebola epidemics, "his statement said. The medical charity Doctors without Borders (MSF),

whom had feared that a sharp decline in cases this year would scupper hopes of proving that a vaccine could work.

as the only real hope for demonstrating the efficacy of a vaccine e


uncovercalifornia.com 2015 000064.txt

#China plans to enforce real names on Social media Chinese government has issued new regulations to eliminate fake social media accounts.


uncovercalifornia.com_business_technology 2015 00445.txt.txt

but not part of the health care system formally, came forward. Later, another 4, 000 joined and these were usually volunteers within the distance of about one-third of a mile from the patient.


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#Japan to invest $21 million in developing 3d printed human organs Could 3d printable human organ transplants become a reality in the coming years?


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and going in and out of the hospital for efforts to control it. At one point, the doctor even said that they were out of options. seriously,

Thankfully, a team of pediatric medicine professionals from Miami Children Hospital were able to scan Gonzalez heart and produce a 3d printed model

Thanks to the success of Gonzalez surgery, Miami Children Hospital plans on using 3d printing in the future for other surgical procedures."


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Recently, additive manufacturing played a significant role in the development of a revolutionary new medical device that,


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More recently, doctors at the Xiangya Hospital of Urology at Central South University in China were able to leverage 3d printing technology in an effort to help successfully remove a tumor from a 60-year-old woman kidney.


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While lives are already being saved by high-level 3d printing in academic hospitals all over the world, most of these cases involve 3d printed implants

Various institutes and hospitals all over the world are experimenting with new materials and applications, but most won result in practical solutions for years.

as an estimated 21 people waiting for organ transplants are dying every single day. And this is exactly where CELLINK comes In this Swedish company lead by Erik Gatenholm

At age 18, Erik Gatenholm started his first medical device company, manufacturing meniscus implants and other implants, such surgical meshes for ventral hernia repairs and wound dressings.


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people in regular hospitals. However, one Chinese company is already implementing a bioprinted product on a large scale across the world.

they have grown out to become a global leader in the field of implantable medical devices, and the Redura is just one of the many products they have released.

and has been used in world renowned hospitals such as Cambridge university Hospital. So far, no reports of adverse reactions have been made

he said. he plan is to develop more than 10 kinds of implantable medical devices products within the next 5 years.


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Unfortunately, many common diagnostic tools, such as enzyme-linked immunosorbant assay (ELISA), require large and expensive readout instruments that can only be found in well-equipped hospital labs. Now,

and vaccination tracking campaigns in resource-poor and field settings. In addition to serving low-resource or remote areas, the researchers noted that intrinsic wireless connectivity can serve epidemic-related studies,


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This week, it was announced by the Children's Hospital of Philadelphia that the surgery, which occurred in early July,

and involved a team of 40 doctors and nurses from the Children's Hospital, Penn Medicine,

and Shriners Hospital for Children in Philadelphia. According to Dr. Benjamin Chang, a surgeon who was on Zion hand transplant team, the complicated surgery involved uniting 2 bones, 2 deep arteries, 4 veins, 10 nerves, and 22 tendons."(


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with low-cost prosthetics acting as a clear example of just how personal and affordable medical devices can be.


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it is used in many hospitals all over the world. Among other applications, ELISA tests can be used to determine

or tracking vaccination campaigns in most resource-poor settings. It fantastic for an undergrad to be first author on the publication.


www.azonano.com 2015 00189.txt.txt

which is still the gold standard in the health care industry for making a definitive diagnosis. Also routinely used today is a newer method for rapidly identifying bacteria based on a DNA-analysis technique called quantitative polymerase chain reaction (qpcr),

"Why Speed Matters in Infection Control In hospitals and clinics worldwide, bacterial infections are a major source of illness,

For that reason, many hospital-acquired infections are treated presumptively, before they are identified definitively, using broad-spectrum antibiotics.

and improving outcomes for people with hospital-acquired infections though the effectiveness of the approach remains to be proven in future clinical trials.

In addition to helping in the clinic the new method may be useful in the food industry or for homeland security applications.


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and is registered FDA as a Class 1 medical device in the U s a CE mark in the EU

It was released in June 2011 and donated to the BC Cancer Agency at Vancouver General Hospital.


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Thanks to this, the article published today in PLOS ONE describes a new step towards the creation of a vaccine,

This technique could be a much better candidate for a human vaccine. The invention is protected commercially

to start clinical trials on human candidates for preventive vaccination and to cure the disease by combining the vaccine with regenerative therapies.

The Germans Trias Institute plans to carry out these steps with patients at the hospital and to optimize the product by dosage and guideline studies.

It is planned also to optimize the product for personalization. To achieve these objectives more competitive funding will be necessary from public agencies.


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was conducted by an interdisciplinary team of researchers from the NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the University of Pennsylvania, Wayne State university/Detroit Medical center

, Seoul National University and Asan Medical center in South korea.""We believe that this technology may be used to address questions that are difficult to answer with current placenta model systems


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which is why the chances of developing an effective vaccine have been deemed low.)They show that this new formulation reduces the minimal curative dose in a disease model, based on infections in mice, by 100-fold and,


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"With this technology hospitals that have no resources can apply the needed drugs, without requiring a a specialist or a particular facility for the administration.

and Innovation and plans to conclude the Clinical Research regulated by the Federal Commission for Protection Against Health risks (COFEPRIS) next year.

and a specialized retina Ophthalmology Clinic provides consultation, which also has an area of`Biotechnology and Drug Research of Biomedical engineering, Diagnosis and Treatment Equipment.


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to $289 billion annually in unnecessary health care costs from additional hospital visits and other issues.


www.azonano.com 2015 00474.txt.txt

Technology areas of interest include cloud applications, analytics, social media, mobile, materials, medical devices, digital health, healthcare IT, instruments and cloud software infrastructure.


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and heavy metals, will revolutionize medical device industry. s


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#Novel Method Utilizes Nanoparticles and UV LIGHT to Isolate, Extract Contaminants In a new paper published this week in Nature Communications,

and an expert in nanoengineering for health care and medical applications. hen you think about field deployment,


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and the University Hospital Zurich thus teamed up to develop the sensor Glucolight which gages the blood sugar level through the skin without taking any blood.

A microdialysis measuring head which was developed at the University Hospital Zurich with a smart membrane developed at Empa;

and the first clinical studies are scheduled at the University Hospital Zurich for 2015. However it could be years before the use of Glucolight becomes standard.

Empa and the University Hospital Zurich are currently in negotiations with partners for the industrial production of the sensor.


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In particular wearable vital sign monitoring devices is set to revolutionize the healthcare and medical devices industry over the next few years.

and medical devices said Ching-Yen Tsay Chairman of ITRI. This reflective pulse oximetry sensor is just the beginning of a line of wearable solutions that Taiwan Biophotonic Co. will be introducing this year.


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Neosense Technologies collaborates with both KTH, Karolinska University Hospital and Uppsala University Hospital s


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#Portable, Autonomous Device Analyzes Trace elements in Water, Air and Upper atmosphere Researchers from Arizona State university School of Earth and Space exploration have combined their sensors,

Youngbull envisions use of the device in homeland security, mass transit, public spaces, hospitals, schools, food production and combat theater analytics.


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Concerned about these alarming statistics, experts at the Johns Hopkins Bloomberg School of Public health Center for Injury Research and Policy challenged a team of Johns Hopkins undergraduate mechanical engineers to design

said Kavi Bhalla, assistant professor at the university Bloomberg School of Public health and one of the team mentors for the project.

Andrea Gielen, director of the Johns Hopkins Center for Injury Research and Policy at the Bloomberg School of Public health and one of the team mentors, said she


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& White Memorial is one of six hospitals in Texas and the first hospital in the Baylor Scott & White Health system to offer the device.

For more information watch this short video, click New Tech Helping Heart failure Patientse are always looking for new and innovative ways to treat our patient disease process

decreasing their chance of being readmitted to the hospital, and improving their quality of life. emorial implemented the Cardiomems HF System


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Wong thought the same thing. earing a mouth guard is less intrusive than spending time in a sleep clinic,

Wong said. he advantage is that the guard extends the treatment beyond the time spent in the clinic,


www.bbc.com 2015 00007.txt

and end up at the clinic with health problems. In 2009, Indonesia passed a law banning fires on peat plantations.


www.bbc.com_science_and_environment 2015 00465.txt.txt

"Morphine plays a vital role in pain relief in many hospitals, but it requires a poppy harvest to manufacture.


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The operation, at Manchester Royal Eye Hospital, is the first time it has been implanted in a patient with age-related macular degeneration (AMD)

and was led by Paulo Stanga, consultant ophthalmologist and vitreo-retinal surgeon at Manchester Royal Eye Hospital and professor of ophthalmology and retinal regeneration at the University of Manchester.

Four more patients with dry AMD will receive the implant at Manchester Royal Eye Hospital,

which aims to bring new drugs and medical devices to patients. Cathy Yelf, of the Macular Society, said:"


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#Scientists find molecular switch that creates long-term immunity Melbourne researchers have identified a protein responsible for preserving the antibody-producing cells that lead to long-term immunity after infection or vaccination.


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""The hope for a definitive cure and an effective vaccine has been frustrated by HIV's endless propensity to subvert the host's defences


www.biologynews.net_ 2015 00139.txt.txt

A team of scientists at Johns Hopkins Bloomberg School of Public health now find that a Kupffer cell protein called CD68 is needed for parasite passage and efficient liver infection,


www.biologynews.net_ 2015 00148.txt.txt

Oren Shibolet, Head of the Liver Unit at the Tel-aviv Sourasky Medical center, who was involved not in this study."


www.bionews.org.uk 2015 00065.txt.txt

The team, from Great Ormond Street Hospital in London, showed that the blood test could detect Down's syndrome in 99 percent of cases.

'The test-known as RAPID-is already available privately at Great Ormond Street Hospital. Later this month, the researchers will present their findings to the UK National Screening Committee,


www.bionews.org.uk 2015 00070.txt.txt

'said Dr Daniel Lachance from the Mayo Clinic, Minnesota, who was involved in one of the studies, both

The studies, one led by the Mayo Clinic and University of California, San francisco, and the other coordinated by the National institutes of health, analysed 1, 380 tumours in total.

Writing in an editorial, Dr David Ellison of St jude Children's Research Hospital, said:''Both studies can justifiably claim that molecular classification captures the biologic features of glioma variants better than does histopathological evaluation,


www.biopharma-reporter.com 2015 00200.txt.txt

which are used already in the clinic. The active drug part can sit within the shell, inside another layer of liquid,


www.biosciencetechnology.com 2015 01057.txt.txt

Bringing techniques and testing that is normally confined to a laboratory or hospital, out into the field,

unlike traditional techniques that are using instruments that you normally find in a lab or hospital,

and enable telemedicine and mobile health, but there also another angle that makes them attractive,

It can also be used for simple tests that are done normally only at hospitals such as total count of red or white blood cells.


www.biosciencetechnology.com 2015 01090.txt.txt

and can turn a routine hospital stay into a nightmare. A 2015 Health Canada report estimates that superbugs have already cost Canadians $1 billion,


www.biosciencetechnology.com 2015 01123.txt.txt

a surgical team from the recipient medical center is dispatched to the donor location to visually inspect

which can be used in any hospital, could help increase the number of donor livers and help save very sick patients waiting for transplant.


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or patients who stayed near him at the hospital before he was diagnosed and isolated, and their family members.

The statement said both stayed at the same hospital with the first patient. Health officials said Tuesday that about 750 people in South korea were isolated at their homes

More than 50 schools and kindergartens near a hospital near Seoul where the 58-year-old patient who died was treated have canceled classes from Wednesday to Friday to let children stay home, according to the education agency in Gyeonggi province,

China isolated the South korean man at a hospital, and Hong kong authorities said Sunday that 18 travelers were being quarantined

170 cases of the virus worldwide and about 480 of the patients have died, according to the European Center for Disease prevention and Control.


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#Team Develops Transplantable Bioengineered Forelimb in Animal Model A team of Massachusetts General Hospital (MGH) investigators has made the first steps towards development of bioartificial replacement limbs suitable for transplantation.


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Ph d.,an assistant professor of biomedical informatics at Columbia University Medical center (CUMC) and Columbia Data science Institute.

688 diseases against the birth dates and medical histories of 1. 7 million patients treated at Newyork-Presbyterian Hospital/CUMC between 1985 and 2013.


www.biosciencetechnology.com 2015 01177.txt.txt

the multidisciplinary team also included Michel Gilliet of Switzerland Lausanne University Hospital and Jure Dobnikar and Daan Frenkel of the University of Cambridge.


www.biosciencetechnology.com 2015 01207.txt.txt

#MERS Not Given Same Vaccine Attention as Ebola, Other Viruses A MERS outbreak has infected about 150 people in South korea,

But a vaccine is not among their tools since it doesn yet exist, and is probably not close to being developed.

has no vaccine, according to the Centers for Disease Control and Prevention. MERS was discovered only in 2012 in Saudi arabia.

However, fewer companies have worked on vaccines and drugs for the MERS virus, according to Reuters. Small biotech companies such as Greffex,

Inovio and Novavax have done all some investigation on vaccines for the sickness but the research is still all preclinical,

Ebola research, including vaccines and treatments, dominated headlines worldwide in the wake of the outbreak of the virus in multiple West african nations last year.

000 doses of its Phase I trial vaccine in Africa. However, other viruses were also acingfor deployment amid the panicked fears as that outbreak spread.

The SARS vaccine work proceeded for years but since the virus mostly disappeared, there are not enough live examples of disease to effectively test it, according to multiple reports.


www.biosciencetechnology.com 2015 01282.txt.txt

to $289 billion annually in unnecessary health care costs from additional hospital visits and other issues.


www.biosciencetechnology.com 2015 01293.txt.txt

The research was conducted by teams from Mcgill University, The Hospital for Sick Children (Sickkids), and Duke university

said Michael Salter, M d.,Ph d.,Head and Senior Scientist, Neuroscience & Mental health at Sickkids and Professor at The University of Toronto,


www.biosciencetechnology.com 2015 01307.txt.txt

The array has been optimized in collaboration with Professor Jacqueline Schoumans from the Lausanne University Hospital in Switzerland, an expert in both acgh and cancer genomics.


www.biosciencetechnology.com 2015 01416.txt.txt

scientific advances that result from collaborations between academic medical institutions and private industry. ource: University of Marylan n


www.biosciencetechnology.com 2015 01465.txt.txt

'"Smartphone apps are the latest tools to emerge from the intersection of health care and Silicon valley,

Apple had created previously software called Healthkit for apps that track iphone owners'health statistics and exercise habits.

Dorsey said that's more objective than a process still used in clinics, where doctors watch patients tap their fingers


www.biosciencetechnology.com 2015 01475.txt.txt

will enter the clinic in the future. here actually well-trodden ground putting modified T cells into patients.


www.biospace.com 2015 01940.txt.txt

Aarhus University Study A major epidemiological registry-based study from Aarhus University and Aarhus University Hospital indicates that Parkinson's disease begins in the gastrointestinal tract.

Now researchers from Aarhus University and Aarhus University Hospital have taken an important step towards a better understanding of the disease.


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Cedars-Sinai Medical center Study Enriched Blood cells Preserve Cognition In Mice With Features Of Alzheimer's disease Los angeles-July 6,


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#Could Dissolvable Microneedles Replace Injected Vaccines? Osaka University Study Eric is terrified. He stands outside the clinic and takes a few deep breaths before walking slowly through the automatic doors.

The nurse reassures him as he takes a seat. But then he sees it: the needle.

and studies suggest that around 1 in 12 people cite fear as their reason for not getting vaccinated.

A new vaccine delivery system could solve this problem: dissolvable microneedle patches are simple to use, pain-free and effective.

Flu vaccines delivered using microneedles that dissolve in the skin can protect people against infection even better than the standard needle-delivered vaccine,

The authors of the study, from Osaka University in Japan, say their dissolvable patch the only vaccination system of its kind could make vaccination easier, safer and less painful.

Downsizing to address the needle problem Most vaccines are injected under the skin or into the muscle using needles.

often causing them to avoid vaccination. The new microneedle patch is made of dissolvable material, eliminating needle-related risks.

where healthcare resources are limited. ur novel transcutaneous vaccination using a dissolving microneedle patch is the only application vaccination system that is readily adaptable for widespread practical use,

we believe it will be particularly effective in supporting vaccination in developing countries. The new microneedle patch Microhyala is dissolvable in water.

taking the vaccine with them. The researchers compared the new system to traditional needle delivery by vaccinating two groups of people against three strains of influenza:

A/H1n1, A/H3n2 and B. None of the subjects had a bad reaction to the vaccine,

people given the vaccine using the microneedles had an immune reaction that was equal to or stronger than those given the vaccine by injection. e were excited to see that our new microneedle patch is

just as effective as the needle-delivered flu vaccines, and in some cases even more effective, said Dr. Nakagawa. e have shown that the patch is safe and that it works well.

Since it is also painless and very easy for non-trained people to use, we think it could bring about a major change in the way we administer vaccines globally.

New approaches to vaccination According to the World health organization immunization prevents an estimated 2 million to 3 million deaths every year.

The continued threat of pandemics such as H1n1 swine flu and emerging infectious diseases such as Ebola makes vaccine development and mass vaccination a priority for global healthcare.

Delivery methods that do not require needles are safer for the person administering the vaccine,

more pleasant for the person receiving the vaccine, and potentially less expensive. The challenge is developing a delivery method that gets the vaccine into the body effectively.

Microneedles provide one such delivery method, and they can be made of various different materials. Previous research has evaluated the use of microneedles made of silicon or metal

but they were shown not to be safe. Microneedles made from these materials also run the risk of breaking off in the skin, leaving tiny fragments behind;

For some diseases, vaccines may be more effective when theye absorbed through the mucous membranes in the nose.

For example, studies in mice have suggested that tuberculosis vaccines delivered through the noseare more effective than those that are injected,

either alone or as an adjunct to traditional parenteral methods of vaccine administration. e


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