The structural knowledge may help others engineer small molecules that inhibit DNA replication at specific moments leading to new disease prevention
and social inclusion of the users as they gain better access to education employment health care and social activities she adds.
Achim Weber from Zurich University Hospital and Dr. Monika Wolf Institute of Surgical Pathology University Hospital Zurich.
#Defective gene renders diarrhea vaccine ineffective Acute diarrheal illnesses cause nearly one-fifth of all child deaths in developing countries.
Today vaccination is considered the most important method for reducing mortality. Unfortunately several studies have shown that the two available living vaccines Rotarix and Rotateq
which are recommended by bodies including the World health organization are not sufficiently effective in developing countries. In many African countries protection has been as low as 20-50%.
%The current study to be published in the Journal of Clinical Infectious diseases by Johan Nordgren from Professor Lennart Svensson's research group shows that up to four of ten children in Burkina faso are genetically resistant to the virus strains found in the vaccines.
The researchers found that children who can not express a particular sugar molecule in the small intestine called the Lewis molecule do not become infected by the rotavirus types found in existing vaccines.
This means that these children do not get the desired immunological protection from the vaccine.
and can greatly impact the evaluation of the rotavirus vaccines now being introduced in several developing countries.
The results could lead to a review of the vaccine composition and the development of vaccines better suited to the populations most affected by rotavirus.
Story Source: The above story is provided based on materials by Linköping University. Note: Materials may be edited for content and length.
and health services. In addition the market is strong for nearly all types of new degree-holders.
and therapies that can be tested in the clinic provides the greatest hope for brain cancer patients
and their families says Weiss leader of the university's Brain and Mental health strategic research priority.
The research paper published today in the Lancet was authored by researchers from UCL Basel University Switzerland the London School of Hygiene & Tropical Medicine the University Medical center Utrecht Netherlands Sheffield Teaching Hospitals
and represent a huge financial burden to the health care system. While NEC continues to be a significant cause of mortality
and the U s. Microsporidia are a large group of extreme parasites that invade humans and animals and cost great damage for health care systems and in agriculture;
Collaborating with Ian Paul a pediatrician at the Penn State Milton S. Hershey Medical center they took samples of blood and of cells inside the cheek from 39 healthy mother-child pairs.
A new study led by investigators at Beth Israel Deaconess Medical center (BIDMC) now finds that blood levels of the hormone Fibroblast growth factor 21 (FGF21) increases rapidly acutely and robustly after fructose ingestion.
at The Ohio State university Comprehensive Cancer Center--Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.
Dr. Julia White of Ohio State's Comprehensive Cancer Center--James Cancer Hospital and Solove Research Institute has helped develop a modified treatment board that allows patients to lie comfortably on their stomachs
The above story is provided based on materials by Ohio State university Wexner Medical center. Note: Materials may be edited for content and length h
This ground-breaking study was set up under the leadership of Brigitte Eisenwort together with Thomas Niederkrotenthaler and Benedikt Till (both from the Institute for Social medicine at the Meduni Vienna's Centre for Public health) as well as Barbara Hinterbuchinger from the University
For this purpose the KIT scientists established a pilot plant at the hospital of Wonosari There bacteria in the water are reduced among others by UV radiation
and hence are suited mainly for urban facilities such as schools and hospitals. In the villages where power is need lacking we much simpler technologies Obst says.
By a pipeline system fecal sludge of the hospital enters a two-stage unaerobic reactor where it is mixed with biowaste.
It is used then for the gas stoves in the kitchen of the hospital. The remaining solid is applied as a fertilizer on the fields in the vicinity.
#Bioinspired coating for medical devices repels blood, bacteria From joint replacements to cardiac implants and dialysis machines medical devices enhance
or save lives on a daily basis . However any device implanted in the body or in contact with flowing blood faces two critical challenges that can threaten the life of the patient the device is meant to help:
They developed a new surface coating for medical devices using materials already approved by the Food and Drug Administration (FDA.
Ingber is also the Judah Folkman Professor of Vascular Biology at Harvard Medical school and Boston Children's Hospital as well as professor of bioengineering at Harvard School of engineering and Applied sciences (SEAS.
--so we further adapted our approach by capitalizing on the natural roughness of chemically modified surfaces of medical devices said Aizenberg who leads the Wyss Institute's Adaptive Materials platform.
The Wyss team developed a super-repellent coating that can be adhered to existing approved medical devices.
While most of the team's demonstrations were performed on medical devices such as catheters and perfusion tubing using relatively simple setups they say there is a lot more on the horizon.
We feel this is just the beginning of how we might test this for use in the clinic said co-lead author Daniel Leslie Ph d. a Wyss Institute Staff Scientist who aims to test it on more complex systems such as dialysis machines
Reflecting the strong collaborative model of the Wyss Institute the cross-disciplinary team included researchers representing the Wyss Institute SEAS Harvard Medical school and Boston Children's Hospital
What emerged could become a new paradigm for implantable medical devices extracorporeal circuits and more. Story Source:
and child care centers to report illnesses to local public health departments could improve the detection of disease outbreaks
and improve public health response to outbreaks during a presentation at 2: 09 p m. PDT in Marina Ballroom Salon E at the San diego Marriott Marquis."For example,
"says Andrew N. Hashikawa, M d.,F. A a. P.,a pediatric emergency physician at the University of Michigan's C. S. Mott Children's Hospital.
Previously some public health departments have found that school absenteeism as a marker for illness was delayed imprecise
Most public health departments do not electronically track influenza or stomach illnesses in preschools and child care centers settings."
"Most illness reporting methods used by many public health departments are based slow, paper and inefficient, "says Hashikawa.
Researchers sent data electronically to the public health department weekly or more frequently if spikes in illness cases were seen.
when patients are moved within the hospital or transported to other facilities. In experiments on laboratory mice Tse used radio waves to probe Bao's wireless sensor allowing him to monitor changes in intracranial pressure continuously.
Because antibiotic prescribing is often inappropriate Jeffrey S. Gerber M d. Ph d. of Children's Hospital of Philadelphia
His son was moved to an academic medical center where he had surgery and was put on four newer antibiotics.
Stunningly the two that worked were the older drugs he had been given at the clinic. I can only assume that
if we had gone straight to the academic medical center he might not have survived Kinch said. It's not that my son had had extensive exposure to antibiotics Kinch explained carefully.
and practice cultures across our health system increases the generalizability of our findings to other health care settings.
or biological contaminants with far-reaching implications for public health including homeland security concerns. Applying world class research to water quality has to be viewed as a critical component for sustaining society as a whole says Clarkson University President Tony Collins. As healthy water becomes increasingly scarce establishing real-time data as the new standard for understanding water quality around the globe
and tax base needed to fund pensions health care and other benefits for the elderly it is typically families that bear the brunt of the cost of having children the study found.
and Barnes-Jewish Hospital in St louis. The team's findings were published online Oct 8 in the Journal of Clinical Investigation.
The researchers were alerted to the connection by a patient who had surgery at another hospital to have a metal rod implanted to repair a fractured ankle.
which led surgeons at the other hospital to remove it. But the rash persisted and a few years later a rare form of skin cancer known as Marjolin's ulcer developed at the surgical site.
and removed by physicians at Barnes-Jewish Hospital. The researchers showed in mouse models that chronic skin inflammation caused by continuous skin contact with allergens contributes to tumor development.
Columbia University Medical center (CUMC) researchers have found that loss of a gene called KLHL9 is the driving force behind the most aggressive form of glioblastoma, the most common form of brain cancer.
Vipul Patel, M d.,medical director of the Global Robotics Institute at Florida Hospital in Orlando."
Now, researchers from The Ohio State university Wexner Medical center and Nationwide Children's Hospital have developed a new rapid screening test that could help physicians know exactly what type of sinusitis they are dealing with
and a positive step towards addressing the major public health issue of antibiotic overuse.""Investors seem to agree.
Bakaletz, who is director of the Center for Microbial Pathogenesis at Nationwide Children's Hospital
In a collaboration among the Jaffe Food Allergy Institute The Mindich Child Health and Development Institute Immunology Institute and Tisch Cancer Institute at The Mount sinai Hospital researchers exposed mice
The above story is provided based on materials by The Mount sinai Hospital/Mount sinai School of medicine. Note: Materials may be edited for content and length.
like substance use disorders, mental health issues and unemployment. At community courts, the criminal case management process itself involves providing access to treatment and social services.
That's one of several types of sensation Spetic, of Madison, Ohio, can feel with the prosthetic system being developed by Case Western Reserve University and the Louis Stokes Cleveland Veterans Affairs Medical center.
a technology in limb prostheses pioneered by associate professor Rickard Brånemark and his colleagues at Sahlgrenska University Hospital.
Thanks to a leading-edge procedure performed at UT Southwestern Medical center Mrs. Henderson is now breathing
and why it is challenging for researchers to develop vaccines targeting the HIV envelope proteins,
Dry powder inhaler formulation Despite advances in vaccination and antimicrobial therapy, community-acquired pneumonia remains a leading cause of morbidity and mortality, even in highly developed countries.
Community-acquired pneumonia, a type of lung inflammation contracted outside of a hospital or nursing-home setting, is caused most often by infections with bacteria, such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus.
Now Zeng and colleagues from the University of Kansas Medical center and KU Cancer Center have published just a breakthrough paper in the Royal Society of Chemistry journal describing their invention of a miniaturized biomedical testing device for exosomes.
The above story is provided based on materials by Brigham and Women's Hospital. Note: Materials may be edited for content and length.
Medical center. Results of the study are published in the Journal of American College of Cardiology Heart failure.
and it's one of the most common reasons people are hospitalized said Abraham director of the Division of Cardiovascular Medicine at Ohio State's Wexner Medical center.
The above story is provided based on materials by Ohio State university Wexner Medical center. Note: Materials may be edited for content and length h
is always deadly for those unable to obtain vaccines in time. Some 55,000 people die from rabies every year.
The above story is provided based on materials by Cedars-Sinai Medical center. Note: Materials may be edited for content and length h
With the support of a grant from the Undergraduate Research and Creative Activities (URECA) Center Lee teamed up with Craig Hamilton an associate professor of biomedical engineering at Wake Forest Baptist Medical center
At the Wake Forest Medical center doctors use replica bodies to help train surgeons to use the Da vinci system Lee said.
#Cell-Squeezing Device Opens New Possibilities for Cell-Based Vaccines A newly published study details how researchers from MIT developed a new microfluidic cell-squeezing device, opening new possibilities for cell
-based vaccines. MIT researchers have shown that they can use a microfluidic cell-squeezing device to introduce specific antigens inside the immune system B cells,
and implementing antigen-presenting cell vaccines. Such vaccines, created by reprogramming a patient own immune cells to fight invaders,
hold great promise for treating cancer and other diseases. However, several inefficiencies have limited their translation to the clinic
and only one therapy has been approved by the Food and Drug Administration. While most of these vaccines are created with dendritic cells,
a class of antigen-presenting cells with broad functionality in the immune system, the researchers demonstrate in a study published in Scientific Reports that B cells can be engineered to serve as an alternative. e wanted to remove an important barrier in using B cells as an antigen-presenting cell population,
A new vaccine-preparation approachdendritic cells are the most naturally versatile antigen-presenting cells. In the body, they continuously sample antigens from potential invaders,
when for cell-based vaccines: They have a short lifespan, they do not divide when activated,
which has limited options for B-cell-based vaccine programming. Using Cellsqueeze circumvents this problem, and by being able to separately configure delivery and activation,
researchers have greater control over vaccine design. Gail Bishop a professor of microbiology at the University of Iowa Carver School of medicine and director of the school Center for Immunology and Immune-Based Diseases, says that this paper presents a reative new approach with considerable potential in the development
of antigen-presenting cell vaccines.?The antigen-presenting capabilities of B cells have often been underestimated, but they are being appreciated increasingly for their practical advantages in therapies,
in this new study, demonstrates promise as a versatile platform for creating more effective cell-based vaccines. ur dream is to spawn out a whole class of therapies
Future stepsthe researchers say they now plan to refine their B-cell-based vaccine to optimize distribution and function of the immune cells in the body.
A b-cell-based approach could also reduce the amount of patient blood required to prepare a vaccine.
patients receiving cell-based vaccines must have drawn blood over several hours each time a new dose must be prepared.
and cost required to engineer cell-based vaccines. e envision a future system, if we can take advantage of its microfluidic nature,
you could do it in your hospital or your doctor office. s the biology and technology become further refined,
run it through a bedside device that has the antigen you want to vaccinate against, and then you have the vaccine,
Szeto says. This research was funded by the Kathy and Curt Marble Cancer Research Fund through the Koch Institute Frontier Research Program, the National Cancer Institute, the National Institute of General medicine Sciences
Tseng collaborated with HSCI Lee Rubin and researchers at the National institutes of health, the Joslin, Boston University, Beth Israel Deaconess Hospital,
and an expert in nanoengineering for health care and medical applications. hen you think about field deployment,
Kenya offers free Antiretroviral Therapy (ART) at clinics throughout the country, but the problem has been a lack of access.
Clinics have to track their drugs, generate tedious reports to get new supplies and deliver those reports to central facilities.
the clinic wouldn get the drugs it needed to treat its patients. The 3g technology has allowed clinics to computerize much of their administrative work,
streamlining the submission process and saving time. The time needed to prepare three monthly reports dropped from 11.6 hours to less than half an hour.
Projects run the gamut from health care and public safety to education and entrepreneurship. A project in India is helping to educate migrant children.
That same amount of money could provide them more permanent housing, comprehensive health care and employment services.""A considerable amount of public dollars is spent essentially maintaining people in a state of homelessness,"Dennis Culhane,
The formerly homeless can get mental health treatment counseling or other services to help them overcome their demons,
our health care to be patient-centric and our education to be student-centric, "O'sullivan explains of the growing market opportunity."
their treatment options are limited to antibiotics, blood transfusions, and fluid supplements to deal with the symptoms of the disease.
Citizens Health care Working group (CHCWG:##Under the direction of Health and human services, CHCWG commissioned by Congress to enlist citizens to provide input to review health care system.
Grant Thorton reports that a collaborative solution was up and running in less than one month.##
and Case Western Reserve's work applying high-definition multipoint video conferencing to telemedicine. Sue Spradley also pointed out that U s. Ignite is seeking not only to incubate new applications
As next-generation genome sequencing heads into the clinic and public health, it ll be targeted at people who don t necessarily fully understand these issues.
Basically, that inhibits the ability to do good public health analyses of bacterial genomes. The work was published in Nature Biotechnology this week.
the Obama Administration has been pushing EHRS as the solution to all that ails health care. The idea is that the data they collect can drive change,
This was proven for me today, through an interview with Paul Hensler (above), CEO of the Kern Medical center in Bakersfield, California.
Kern, a county hospital, has needed an EHR for some time. But getting a commercial system meant writing a Request for Proposal (RFP) for a consultant who would write an RFP for a system,
The information can also be used to prove to insurers that the money they spend on health care is producing results. ealth care providers are more and more being paid for outcomes,
when a hospital-based experiment proved, in principle, that it was possible to achieve near-normal blood-sugar control.
Essentially, doctors at the Columbia University Medical center have been able to print a knee meniscus using a degradable plastic scaffold and a protein growth system.
a care management platform designed to help low-income Utah residents suffering from mental health issues.
Utah Smartcare partners with three local mental health authorities and 2 community health clinics in Utah.
one of the local mental health authorities participating in the Utah Smartcare initiative. his data will allow us to better assess how our clients are doing between appointments
Ginger. io is working separately on projects with UC San francisco, Partners Healthcare (Massachusetts General Hospital, Brigham and Women Hospital,
and Mclean Hospital), Duke university, UC Davis and University of Nebraska Medical center i
#TV s Disruption On Display As Netflix And Amazon Go Head-To-Head At Golden Globes More proof that good television doesn have to be developed by traditional industry players:
#It s the most ubiquitous medical device in the world and we re simply piggybacking off of and improving regular behavior.#
The Kinsa costs $29. 99 and alongside hardware sales the company is considering how they can be a communications layer for other companies working on telemedicine prescription delivery and other startups in the health ecosystem.
and even health tech that organizes patient information for hospitals f
#Secret Media Makes Ad Blockers Useless To Display Those Sweet, Sweet Pre-Roll Video Ads Chances are installed that you an ad blocking extension to skip Youtube pre-roll video ads.
Lin says. e fit in as part of that first step into telemedicine. Like Scanadu devices, the Clinicloud medical kit hooks information from the app up with remote physicians.
but could expand to include other telemedicine services in the future. The other thing to keep in mind about the kit is the price.
and Boston Children Hospital wants to make it easier for educators therapists and parents to collaborate so kids get the help they need.
and Dr. Howard Shane who leads the Autism Language Program and the Center for Communication Enhancement at Boston Children Hospital.
how to boost the operational efficiency of hospitals and improve patient care by helping staff make better choices about how resources are allocated.
Its founders liken their product to an ir traffic controller for the hospital and healthcare system Their real-time analytics platform predicts changes in demand
And while Analyticsmd does offer its own real-time dashboard view too its added layer of data processing helps hospitals achieve greater operational efficiencies by providing a nudge ahead of time.
and let the hospital know; second: find the root causes, we actually filed some IP on that,
Or even to detect which patients may not have had the best service in the hospital. The team claims one early implementation of its platform was able to cut the number of patient falls in half over a 1. 5 month period,
and that happen to them in hospital are now being processed, and how certain actions might trigger certain healthcare outcomes?
In its current rollouts Garg says is only utilizing data elements that hospitals were already capturing,
They probably just see the hospital as being a lot more responsive. Without necessarily seeing the tech explicitly,
if a hospital started asking for additional decisions that maybe required additional data elements to be captured then the team would efinitely want to have a conversation with the patients to make sure they are comfortable with that Newhouse also points out that Analyticsmd makes a point of not capturing personal data such as patientsnames
while working in hospitals on operational issues where they saw how day to day operational challenges
#Benefits to medical device manufacturers include cost savings through not having to develop a completely new device leveraging existing platforms
or act as accessories to existing medical devices and allow the smartphone to act as a##dumb-user interface
Addressing Two Critical Questionssagentia believes there are two critical questions for medical device companies entering this space:
and incorporate it into a medical device? And equally important how do you make money from doing so?
MMAS should be treated like any other medical device. Risk analysis is key and careful system design will ensure that safety critical functions are implemented appropriately.
Once companies decide to incorporate an MMA they follow the same type of development roadmap used for any other medical device.
development under the ISO 13485 medical device standard.####As an example of how to manage the risks of including apps in connected systems Tighe cites the Verihaler which Sagentia has developed to monitor patient adherence to treatment for asthma or chronic obstructive pulmonary disease (COPD.
With such great opportunities available it s no surprise that many medical device companies have connected health on their agendas.
#Benefits to medical device manufacturers include cost savings through not having to develop a completely new device leveraging existing platforms
or act as accessories to existing medical devices and allow the smartphone to act as a##dumb-user interface
Addressing Two Critical Questionssagentia believes there are two critical questions for medical device companies entering this space:
and incorporate it into a medical device? And equally important how do you make money from doing so?
MMAS should be treated like any other medical device. Risk analysis is key and careful system design will ensure that safety critical functions are implemented appropriately.
Once companies decide to incorporate an MMA they follow the same type of development roadmap used for any other medical device.
development under the ISO 13485 medical device standard.####As an example of how to manage the risks of including apps in connected systems Tighe cites the Verihaler which Sagentia has developed to monitor patient adherence to treatment for asthma or chronic obstructive pulmonary disease (COPD.
With such great opportunities available it s no surprise that many medical device companies have connected health on their agendas.
shortly after returning home from the hospital he set up a workshop in the garage and put those skills to work designing
But bringing bionic devices into the clinic is not easy. Bob Emerson a prosthetist at A Step Ahead Prosthetics who helps connect patients to research projects in Herr's group says it's challenging to persuade insurers to pay for devices like Biom.
they are loading their DNA data into several little-known websites like Promethease that have become, by default, the largest purveyors of consumer genetic health services in the United Statesnd the next possible targets for nervous
maintained by Konrad Karczewski, a postdoctoral researcher at Massachusetts General Hospital, now has 80 to 100 visitors per day, twice as many as last year.
and requires frequent visits to the hospital for hour-long IV infusions something patients desperate to stay alive will put up with but likely not millions of people with high cholesterol.
#Fingerprinting Infants Helps Track Vaccinations in Developing Countries Billions of dollars a year are spent vaccinating children in developing countries
but about half as many immunizations are administered as could be because of unreliable vaccination records. Biometric researchers from Michigan State university have developed a fingerprint-scanning system for children under five years old that could replace ineffective paper vaccination records.
Until now biometrics experts believed fingerprints of babies and toddlers were too unreliable because image sensors are designed for the ridges and valleys of adult fingertips.
Paper-based vaccination records are lost easily and don t reliably provide health workers with up-to-date information on patient history.
The Bill and Melinda Gates Foundation funded the research specifically for recording vaccinations but the patient-identifying system has broader applications says Anil Jain a distinguished professor at Michigan State university s Computer science and Engineering Department and coauthor of the paper.
and death certificates to health care records school enrollments and voter registration. The Michigan State university researchers needed to process images taken from fingerprint sensors using software to compensate for the small size of the children s fingerprints as well as their sometimes wet and oily skin.
because the Benin clinic was outdoors with dust and high humidity but Jain believes match accuracy can be improved to 95 percent in these types of conditions.
Compared to the status quo of not getting vaccinations for life-threatening diseases mothers are not asking these questions
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