| Alkaloid (11) |  |
| Allergan (6) | |
| Astrazeneca (7) | |
| Basi (302) | |
| Bayer (10) | |
| F hoffmann la roche ltd (24) | |
| Glaxosmithkline (15) | |
| Novartis (22) | |
| Pfizer (10) | |
| Sanofi (5) | |
| Alkaloid (11) | |
| Allergan (6) | |
| Astrazeneca (7) | |
| Basi (302) | |
| Bayer (10) | |
| F hoffmann la roche ltd (24) | |
| Glaxosmithkline (15) | |
| Novartis (22) | |
| Pfizer (10) | |
| Sanofi (5) | |
and his investors are onboard on that basis. Etsy CEO Chad Dickerson has hinted the company will take a nontraditional route to paying back its venture capitalists, possibly through recapitalisation and debt financing.
Emory Health Sciences Chemists have made a significant advancement to directly functionalize C-H bonds in natural products by selectively installing new carbon-carbon bonds into highly complex alkaloids
Nature Communications published the findings, emerging from a collaboration with Novartis Institutes for Biomedical Research and Emory University.
"Co-authors are Novartis chemists Rohan Beckwith, Jing He and Lawrence Hamann. The CCHF is at the forefront of a major paradigm shift in organic chemistry.
"Novartis wanted to explore whether this chemistry was robust enough to be carried out on really complex compounds like alkaloids."
"Alkaloids are a family of natural products produced by plants that have biological properties important to medicine.
Morphine, codeine and opioids are examples of alkaloids. A key part of the drug development process is creating libraries of derivatives from such natural products:
Groups of chemical compounds with small molecular differences.""These small differences could determine whether a compound is toxic
The results outlined in the paper demonstrate the efficiency of rhodium catalysts to selectively install a new carbon-carbon bond into complex alkaloids in a highly controlled manner.
"Novartis sees great potential in C-H functionalization, "Davies says.""It has been an early and enthusiastic supporter of the CCFH through collaborative research of scientists at Novartis and in CCHF academic labs
#Enzymes believed to promote cancer actually suppress tumors Upending decades-old dogma, a team of scientists at the University of California,
Published in the February 2015 edition of the Journal of Affective disorders, the findings could provide a biological basis for diagnosing
cloud solutions are updated typically on a frequent basis. As report formats change or new requirements are added,
"We have enough confidence in this product to go live on a day-to-day basis, she says. Similar to the Workday system, Box legal team had to train the DLOOP software to improve the recommendations.
According to the U s. Census bureau, the population here in D c. grows from 584,400 to over 1 million people on a daily basis
on a competitive basis. FTA officials said its Low or No Emission Vehicle Deployment Program (Lono), established under the Moving Ahead for Progress in the 21st Century Act,
could be the basis for a single climate information service for the whole of Europe and for training new experts in communicating climate knowledge.
and monitor these systems on an ongoing basis."The airport operator programmes the system to make connections between data sources and highlight potential threats in real time.
monitoring and measuring on a daily basis enables preparation, prevention and understanding. I think, with this project,
These partners can also consult the EFAS Flood Portal on a daily basis. The portal issues maps of Europe where danger zones are indicated by"hot spots".
both to acquire our system on a licence basis and to form partnerships to deliver water,
After supporting the development of informatics at Avantium he moved to Novartis in Switzerland to expand the company's expertise and now works with the Institute of Cancer Research in London.
This triggers the production of proteins which are of potential pharmaceutical interest as the basis for new vaccines.
"Every medical intervention is judged on a cost-benefit basis . Since this device is implanted on the outer surface of the skull,
which will domuch to help provide a viable basis for thebio-economy as a whole. It will also put Europe at the forefront of whatis sure to be one of the most dynamic andimportant areas of economic and scientificactivity of the future u
Pfizer, Honyewell and Walmart have provided also training materials for the organization, which has trained EHS managers and suppliers from hundreds of companies.
Somewhere there may be a backup system what we call redundancy that might be the basis for better identifying tumors
Odanacatib is produced by Merck & co. Inc. and has gone already through phase III clinical trials with good results Cao says.##
or near-daily basis in 2013 including one in every 11 males and one in every 34 females.
On the basis of the reason selected they were alerted subsequently to reassess the need for the catheter
They also are examining the genetic basis of SAS in the golden retriever, Rottweiler, and other dog breeds.
Pfizer Animal health training grant, and the Newfoundland Club of America supported the research, which appears online in the journal Human genetics r
Bannasch explains that common breeding practices have made the dog a unique animal model to help understand the genetic basis of naturally occurring birth defects.
because they are the basis for an array of consumer products. For instance colloidal dispersions comprise such everyday items as paint milk gelatin glass and porcelain and for advanced engineering such as steering light in photonics.
and efficiency and it occurs on an ongoing frustrating basis. To help laser systems overcome loss operators often pump the system with an overabundance of photons
The materialâ could be the basis for unique electric generators that are lightweight bendable stretchable #and ultimately wearable. his material#just a single layer of atoms#could be made as a wearable device perhaps integrated into clothing to convert energy from your body movement to electricity
and Stroke (NINDS) part of the National institutes of health. t helps scientists study the dynamics of brain circuits that may explain the neural basis of learning. he researchers recorded neural activity in the subject s motor cortex
Byron M. Yu assistant professor of electrical and computer engineering and biomedical engineering at Carnegie mellon believes this work demonstrates the utility of BCI for basic scientific studies that will eventually impact people s lives. hese findings could be the basis
what were used in this study to coach patients to generate proper neural activity. he researchers are part of the Center for the Neural Basis of Cognition (CNBC) a joint program between Carnegie mellon University and the University of Pittsburgh.
#Scientists are first to detect exciton in metals University of Pittsburgh rightoriginal Studyposted by Joe Miksch-Pittsburgh on June 2 2014humans have used reflection of light from a metal mirror on a daily basis for thousands of years
and optical communications that are the basis for the internet and cable TV. The optical and electronic properties of metals cause excitons to last no longer than approximately 100 attoseconds (0. 1 quadrillionth of a second.
All of a sudden the ability to design technologies at the basis of health entertainment travel and social communication will not be limited by plugs
but now we have data on almost all the RNA molecules in a cell more than 10000 different RNASASSMANN says. e are the first to determine on a genome-wide basis the structures of the RNA molecules in a plant
of physics at University of California Santa barbara. n a pixel-per-pixel basis it s a quantum leap from semiconductor detectors;
because it is the basis of so much of our modern technology and applications. In addition most of the silicon in existing devices remains unused
which kept the whole milking machine process organized on a nicely industrial basis. Unfortunately, despite technocratic hopes, farming is not manufacturing
interconnected modules as the basis for their new Snake Monster and the line of reconfigurable robots promised to follow it.
Toyota will consider requests from outside the transportation sector on a case by case basis. Last year,
###letting advertisers target users not only on the basis of their##likes##on the site, but also by correlating that with data about
generating some 11.1 petabytes of data on an annual basis. That s about 30 terabytes a day.
and will be run by Arthur Levinson, chairman and ex-CEO of biotech company Genentech. Google gave exclusive access to Time magazine for a story on the new venture.
Arthur D. Levinson, Chairman and former CEO of Genentech and Chairman of Apple, will be Chief executive officer and a founding investor.
Art Levinson will remain Chairman of Genentech and a director of Hoffmann-la roche, as well as Chairman of Apple.
rt track record at Genentech has been exemplary, and we see an interesting potential for our companies to work together going forward.
Art Levinson, Chairman and former CEO of Genentech and Chairman of Apple, will be Chief executive officer. OK so youe probably thinking wow!
the goal is to provide for all the basic water needs of a person on a daily basis. Final Thoughts Prospects for the Future There are roughly 37,
Prioritizing privacy Questions like these being asked on a daily basis would lead one to believe that yes,
#There are new ideas popping up on a daily basis, many of which are realized eventually in the market.#
But it also hopes the tech will become the basis for the next generation of PCS.
such as a change in the basis of competition, new market entrants and new types of consumers.
noting that many schools don have the technological infrastructure to make ed tech products viable on a consistent basis. Teacher training is another challenge that Chaudhry group has identified.
It challenges not only the basis and underlying assumptions of the modern financial system, but calls into question the beliefs and even livelihood of so many politicians, economic advisors,
was prepared lamp Ambio, the basis of which consisted of the very luminous microorganisms. With the selection of suitable bacteria for the device helped biology-students from Delft University of Technology.
The billboard works on the basis of simple thermodynamic principles. It makes use of shifts in temperature pressure
Billions of marine animals migrate vertically on a daily basis from deep within the ocean's darkest abysses to the surface where they feed at night only to drop thousands of feet back to the depths before dawn.
000 people and, from that, produce 86,000 liters of clean water on a daily basis while also generating a net 250 kilowatts of electricity.
Loans but not grants have been provided on this basis before, for example, through the World bank's Millennium Science Initiative."
One CCR5 inhibitor, called maraviroc, is made by the pharmaceutical company Pfizer and is approved for use in the United states and Europe.
says J#rg H#ser, a champion of the idea who works at Bayer Healthcare in Wuppertal, Germany.
Rosenberg points to a collaboration formed in August last year between June's group and the drug giant Novartis,
Led by Amy Kistler at the Novartis Institutes for Biomedical Research in Emeryville California, the team responded to an outbreak of Theiler's disease at a farm in
The research provides an effective basis for searching for candidate molecules that could be used to treat the condition.
Last month, pharmaceutical giant Allergan bought the worldwide rights to that specific device called Liris (for lidocaine-releasing intravesical system), for $69 million up front and what could total more than $600 million in milestone payments.
Allergan is prepping for phase-three clinical trials for Liris, which can deliver 400 milligrams of lidocaine to patients.
Although future progress now depends on Allergan, Cima hopes to see Liris used commercially in a couple of years.
drew Allergan to invest in and eventually buy the technology. Taris tested the device on IC patients, many of
With the Allergan acquisition funds, Taris will further develop the device to deliver drugs for other bladder diseases,
Last year, Taris entered a research collaboration with Astrazeneca to develop novel treatments for bladder cancer. his device is a platform
#The research was funded by the National institutes of health the Packard Award in Science and Engineering Sanofi Pharmaceuticals Foxconn Technology Group and the Hertz Foundation e
Making the entire data set available on a queryable basis does seem like a significantly larger lift.
and generally an increase in overall efficiency. imulation componentsakselossoftware runs on a novel technique called the educed basis (RB) component method,
which reproduces expensive FEA results by solving related calculations that are much faster with the idea of decomposing larger simulations into an assembly of components. e developed a component-based version of the reduced basis method,
but that s probably tolerable for many applications In the meantime Demaine is planning to revisit the theoretical analysis that was the basis of the researchers original folding algorithm to determine
In the desert environment dust is present on a daily basis says co-author Numan Abu-Dheir of the King Fahd University of Petroleum and Minerals (KFUPM) in Saudi arabia.
With Affdex you see on a moment-by-moment basis who s really engaged with ad and
The discovery of specific genes associated with these disorders provides significant clues to their biological basis and points to possible molecular targets for novel therapies.
discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics;
Creating safeguards against such information leaks will have to be done on a case-by-case application-by-application basis de Montjoye acknowledges
The new approach, described May 18 in Nature Methods, could also help neuroscientists learn more about the biological basis of brain disorders. e don really know
. Lai Fellowship, an Astrazeneca Distinguished Graduate student Fellowship, the National Institute of General Medical sciences, and the National institutes of health M
The research was funded by the National Science Foundation, Novartis, and the Institute for Collaborative Biotechnologies through the U s army Research Office u
which is the basis for uperalloysused in extreme environments, such as in deep-sea oil wells. By creating a computer model of that microstructure and studying its response to various conditions,
basis. Gartner released their predictions on where sensor technology is headed. They predicted that y 2017,30 percent of smart wearables will be inconspicuous to the eyeand y 2016,
Homogeneous arrays of patterns of QDS serve as the basis for corresponding arrays of QD LEDS that exhibit excellent performance.
The team concluded their durable lightweight sensor could serve as the basis for many useful applications.
"Mixing two input signals to get a new output is the basis of computation, "Agarwal said."
and colleagues from the RIKEN Center for Emergent Matter Science the University of Tokyo and Hiroshima University have discovered that ultrathin films of a semiconducting material have properties that form the basis for a new kind of low-power electronics
and low pressure to form the basis of the biosensor. The researchers then patterned graphene devices using semiconductor processing techniques before attaching a number of bioreceptor molecules to the graphene devices.
This result could be the basis for next-generation flexible and transparent computing, better light-emitting diodes,
"Furthermore, this concept can be applied as the basis to produce dynamic three-dimensional color displays. In the area of informatics, these holographic configurations could store information in subwavelength areas.
and form the basis of countless electronic devices such as memory chips photovoltaic cells logic gates and sensors. An interesting alternative to inorganic TFTS (silicon) is organic TFTS (OTFTS)
"These discoveries provide the fundamental basis for the development of improved battery materials, "said Jun Wang."
"It lays the groundwork for a whole new basis of electronics, and in particular, ultra-low-power electronics."
"It has the potential to totally change the world's electronic basis. It's a trillion-dollar prospect. l
A pleasant surprise The geometric basis for such microstructures was determined more than a decade ago, Fang says,
Quantum dots are novel nanostructures that can become the basis of the next generation of solar cells capable of squeezing additional electricity out of the extra energy of blue and ultraviolet photons.
Transistors are the basis of nearly all electronics. Their two settingsn or offictate the 1s and 0s of computer binary language.
they form the basis of both LEDS and LCDS (liquid crystal displays.""This could make a transparent,
All of a sudden, the ability to design technologies at the basis of health, entertainment, travel and social communication will not be limited by plugs and external power sources,
Imagine a fleet of these vehicles whisking payloads to LEO on a daily basis . If multiple countries operate their own fleets there will eventually be multiple payload deliveries per day.
It's going great. the problem is bayer's neonicotinoid pesticides they accumulate in the plants
The constituents are reviewed and rebalanced on a quarterly basis u
#A computer vision system for mining artistic influence When we look at an image we not only recognize object categories
Once this queue is fulfilled bears will be distributed to families on a first come first served basis through our network of affiliate nonprofits.
Robotics infographicthe IPO report also looks at the rate of robotics patents compared to other innovation patents on a country basis
we perform state estimation on the basis of the drone estimates of its height, speeds, angles,
and in the light of the discussion of the marker ambiguity, we decided to only update the position on the basis of the marker readings,
and will now form the basis for what are likely to be difficult negotiations with the Commission, the EU's executive arm.
we are one step closer to defining the computational tools that form the basis for bottom-up materials engineering
provides he ability to pick the best heat-transfer profile on an as needed basis, rather than having to pick a single type of nucleation behavior that allows margins for the most extreme heating that is ever expected for a given device. his allows you to pick the optimum rate of heat transfer moment by moment,
"I think if you look at acquisitions outside of the traditional telco business on a single investment basis this is the largest that we have done."
instead the fund act on a case-by-case basis and that it use its role as a company shareholder to improve corporate practices.
the heavy lifting is done by the inference algorithmhe algorithm that continuously readjusts probabilities on the basis of new pieces of training data.
provide a valid basis for manufacturers'warranties, and provide investors with confidence in their investments. In addition, the group aims to create guidelines for inspecting factories during module manufacturing.
and Professor Lennart Lindfors, of Astrazeneca, Sweden, have mapped out'in diagram format the actual movements made by chemical molecules on their breeding journey using computer simulations.
Because X-ray crystallography doesn reveal the structure of a material on a per-atom basis,
provides he ability to pick the best heat-transfer profile on an as needed basis, rather than having to pick a single type of nucleation behavior that allows margins for the most extreme heating that is ever expected for a given device. his allows you to pick the optimum rate of heat transfer moment by moment,
Though that interpretation allows researchers to create a virtual 3-D model of the heart that serves as the basis for a 3-D printed model
The information would be made available to contacts looking to connect on an on-demand basis,
Downey told Techcrunch that every customer starts on a paid basis since theye mostly industrial or nterpriseclients who already have their own drones,
Moves like these are smart in a world where 1. 8 billion digital photos are shared on a daily basis
change the genetic basis of various traits-from correcting diseasecausing mutated genes to genes that determine
"said Ghodbane, who now works in biopharmaceutical research and development at Glaxosmithkline. The breakthrough also requires one-tenth of the chemicals used in a conventional multiplex immunoassay,
or even on a continuous basis, versus other methods where it could take hours or even days,
who earned his doctorate in biomedical engineering at Rutgers and now works in biopharmaceutical research and development at Glaxosmithkline.
Because X-ray crystallography doesn reveal the structure of a material on a per-atom basis,
Taking phosphatoantimonate nanosheets as their basis the Stuttgart scientists then developed a photonic nanostructure which reacts to the moisture by changing colour. f this was built into a monitor,
The bill would empower the agency to search data held by telephone companies on a case-by-case basis. Bulk collection was revealed in 2013 by ex-security contractor Edward Snowden.
He is confident that there is no legal basis for that and indeed is confident they would see his technology as a"really cool thing".
Dr Sarah Hatsell and her colleagues at Regeneron found that the overactivity of the mutant receptor is caused by its altered response to the signalling molecule Activin-A this molecule normally makes AVCR1 less active,
Regeneron is currently performing preclinical safety testing and may eventually conduct clinical trials if a safe clinical trial can be designed.
'We are very fortunate and grateful that not only did Regeneron make this basic science discovery,
sponsored by a coalition including Thermo Fisher, Pfizer, and the US government, aims at warzone use but the tech could also be applied to public quarantines, personalised medicine,
and at polishing methods for purity. t sounds nutshe project a collaboration between Thermo Scientific, UMBC, Ohio State university, Pfizer, FDA, Latham Biopharm Group, Artisan, Dupont, Fluorometric
, GE, Genentech, Grace, Merck & co.,and Sartorius-Stedim was prompted by a $7. 9m grant from DARPA, the US Defense Advanced Research Projects Agency.
sponsored by a coalition including Thermo Fisher, Pfizer, and the US government, aims at warzone use but the tech could also be applied to public quarantines, personalised medicine,
and at polishing methods for purity. t sounds nuts The project a collaboration between Thermo Scientific, UMBC, Ohio State university, Pfizer, FDA, Latham Biopharm Group, Artisan, Dupont
, Fluorometric, GE, Genentech, Grace, Merck & co.,, and Sartorius-Stedim was prompted by a $7. 9m grant from DARPA, the US Defense Advanced Research Projects Agency.
Military experts believed current pharmaceutical supply methods to battlefields sometimes requiring airdrops were need obsolete, and to be replaced with manufacturing at the point of care specific threat response without requiring specific preparedness.
making that chromosome an important avenue for researching the genetic basis of the cancer. major goal of my laboratory is to identify the specific gene or genes on chromosome 21 responsible for the increased incidence of leukemia in this population,
. who now works in biopharmaceutical research and development at Glaxosmithkline, published their results in the journal Lab on a Chip in addition to being able to use less fluid,
That data will include the raw MRI scans and, on a randomized basis, either a physical model or a computerized 3-D model, based, again at random, on either human segmentations or algorithmic segmentations.
#Britain Becomes First Nation to Offer Meningitis B Vaccine After Tense Novartis AG Stand-Off The United kingdom will officially become the first country in the world to offer a vaccine for meningitis B after to infants covered under its national health system,
after reaching a hard-fought deal with Glaxosmithkline (GSK), said health officials Monday. Britain will now be able to offer Glaxo Bexsero vaccine, formerly part of Novartis AG (NVS) vaccine portfolio under its massive asset swap earlier this year.
Neither part disclosed the cost of the program, but Nikki Yates, general manager of GSK in Britain,
#Genentech???s Alectinib Shrank Tumors in Nearly Half of Patients With Specific Lung cancer Mutation Genentech Investigational Medicine Alectinib Shrank Tumors in Nearly Half of People With Specific Type of Lung cancer--Alectinib showed response rates of up to
69 percent in the central nervous system (CNS) in people with advanced ALK-positive non-small cell lung cancer---Genentech plans to submit these Phase I/II data to the FDA as part of a New
Drug Application for alectinib, which has been granted Breakthrough Therapy Designation--2015 ASCO Annual Meeting SOUTH SAN FRANCISCO, Calif.--BUSINESS WIRE)--Genentech,
a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), today announced positive results from two pivotal studies (NP28673 and NP28761) that showed alectinib,
About Genentech in Lung cancer Lung cancer is a major area of focus and investment for Genentech, and we are committed to developing new approaches,
About Genentech Founded more than 35 years ago Genentech is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions.
The company, a member of the Roche Group, has headquarters in South San francisco, California. For additional information about the company, please visit http://www. gene. com
We believe our design idea could also be applied to other compounds such as terpenoids and alkaloids,
Intelligent mapping systems like HERE's are the basis on which self-driving cars linked to wireless networks can perform functions such as recalculating a route to the nearest electric charging station or around a traffic jam or accident.
We believe our design idea could also be applied to other compounds such as terpenoids and alkaloids,
If 10 pct. of the liposomes created on this basis can survive, then it is plausible that even more will survive
"Sequencing the DNA of CLL has taught us a great deal about the genetic basis of the disease,
These discoveries will form the basis for precision medicine of CLL and other tumor types
This on/off transition, inherent to vanadium dioxide, is also the basis of computer logic and memory.
thanks to a new invention by Duke university engineers. ee invented a sensing system that can efficiently solve an interesting problem that modern technology has to deal with on a daily basis,
By selecting a specific type on the basis of its pore shape, we were able to convert lactic acid directly into the building blocks for PLA without making the larger by-products that do not fit into the zeolite pores. ur new method has compared several advantages to the traditional technique:
< Back - Next >
Overtext Web Module V3.0 Alpha
Copyright Semantic-Knowledge, 1994-2011