In the first demonstration of how the technology works, published July 30 in the journal Cell("Saturated Reconstruction of a Volume of Neocortex"),the researchers look inside the brain of an adult mouse at a scale previously unachievable, generating images
Arrows point to other varicosities of this axon that are innervating dendritic spines of other neurons (data not shown.
which is a way of saying that I would prefer to generate a hypothesis from the data
"The researchers have begun the process of mining their imaging data by looking first at an area of the brain that receives sensory information from mouse whiskers,
The cost and data storage demands for this type of research are still high, but the researchers expect expenses to drop over time (as has been the case with genome sequencing).
To facilitate data sharing, the scientists are now partnering with Argonne National Laboratory with the hopes of creating a national brain laboratory that neuroscientists around the world can access within the next few years."
"As long as data is showing you things that are unexpected, then you're definitely doing the right thing.
when we look at this data that we don't see something that we've never seen before. r
or use computer simulations to visualize how particles can form and attach. The international group met for a three-day workshop in Berkeley, California,
#From cameras to computers, new material could change how we work and play Serendipity has as much a place in science as in love.
from 20-megapixel arrays for cellphone cameras to photo detectors to atomically thin transistors that when multiplied by the billions could fuel computers.
promises to capture all those stray radio waves emitted back and forth between wireless phones and the towers through
extending a smartphone's battery life by as much as 30%.%Announced as part of an upcoming Kickstarter fundraising campaign, the technology,
which Nikola's designers engineered into a special case made for Apple's iphone, reportedly harvests the electromagnetic radiation transferring to and from mobile phones and converts it into direct current (DC) electrical energy,
which is recycled then back into the phone's battery.""Nikola Technology efficiently converts RF signals like Wi-fi, Bluetooth,
and LTE into DC power using its proprietary energy harvesting circuit, "explains the company on its website."
"The result is usable energy that can provide power to mobile devices wirelessly.""Though not perfect by any means, Nikola energy-capturing case holds promise For a sponsorship contribution of $99,
early supporters of the project will gain exclusive first-issue access to the case, which doesn't so much charge an iphone actively as it does extend its normal battery life.
Still, the case's novelty, and more importantly its longer-term potential, is what stands to inspire a new generation to take advantage of energy inefficiency and waste.
One major drawback to the technology is that its relatively slow to harvest energy, and the case itself doesn't contain an actual battery of its own to store excess charge.
At the same time the case itself is small and form-fits well to the iphone, acting as an all-in-one battery extension package that's sleek, discreet and unobtrusive."
"As magical as this sounds, the iphone case won't be able to charge your phone from zero to 100,
%"explains Business Insider about the case, which captures some 90%of the stray signals that would
either--the antenna and power-converting circuit can only extend the battery life of an iphone 6 by about 30,
. and her colleagues evaluated data from the Maternity Practices in Infant Nutrition and Care survey,
Nearly 80 percent of new mothers start out breastfeeding their children, according to the data. However, after about one week following birth, 25 percent of these drop off
Intravenous Vitamin c has that potential based on our basic science research and early clinical data.""Replicating these results in patients
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#Blown-up brains reveal nanoscale details Microscopes make living cells and tissues appear bigger. But what if we could actually make the things bigger?
In one experiment with inflated mouse brain tissue, the researchers gauged the distance between two proteins that sit on opposite ends of neural synapses.
At the meeting, he showed an image of a half-millimetre slab of the mouse brain's hippocampus
Pushing boundaries Viviana Gradinaru, a neuroscientist at the California Institute of technology in Pasadena, says that Boyden technique is another example of how scientists are bypassing hardware limitations by modifying biological tissue.
But teixobactin has disappointed in its failure to kill ram-negativebacteria. This class, says Eisenstein, is a particular health concern
Marvin Andujar and Chris Crawford, have built a mind-machine method to control a drone through a wearable electroencephalographic (EEG) Brain-Computer Interface device.
The drone operates based on user cognitive commands. When the user thinks forward, the drone moves forward towards the direction it is facing.
While the drone flies, the user is able to view the flight from FPV (first-person view) via a front-facing camera. his project serves as the beginning of brain-machine control as a human-centric application says Marvin Andujar
who is also a member of our Neurogadget editorial team. The idea is to use the BCI, drones and other machines such as a humanoid as a third arm for humans.
The next step for this research is to incorporate a two way system that monitors user levels of engagement, cognitive workload
and provide a positive user experience, they need to understand how the users feel. By Marvin Andujarvideo credits:
The Division of Multimedia Properties at University of Florid f
#Jaguar land rover Mind Sense research monitors brainwaves through the hands via sensors in the steering wheel Jaguar land rover has revealed the ixth Senseproject,
a range of new road safety technology research projects that are being developed to reduce the number of accidents caused by stressed and distracted drivers.
With its road safety research, The british firm is joining a number of other car makers that have been researching the measurement of brainwaves to monitor driver concentration in the car.
Even if the eyes are on the road, a lack of concentration or a daydream will mean the driver isn paying attention to the driving task.
or be less aware of other road users so we are looking at how we could identify this
software is used to amplify the signal and filter out the pure brainwave from any background oisejaguar Land rover is currently conducting user trials to collect more information on the different brainwaves identified through the steering wheel sensors
and will involve leading neuroscientists in the project to verify the results. On top of brainwave monitoring, Jaguar land rover is also assessing how a vehicle could monitor the well-being of the driver using a medical-grade sensor embedded in the seat of a JAGUAR XJ.
but also allow the car to monitor driver stress levels. This would then allow the car to help reduce stress, for example by changing mood lighting, audio settings and climate control.
which means users wouldn have to touch the screen itself. In user trials this increases the speed of successful button selection by 22 per cent and therefore reduces the amount of time the driver is looking at the screen with their eyes off the road.
The system could also use mid-air touch to provide the driver with a sensation,
there will be no need for the driver to glance at the screen for visual confirmation which would help keep their gaze on the road ahead.
and drive the car through an electroencephalography (EEG) headset manufactured by Emotiv. The BMW was fitted with a mechanical rig capable of pressing the pedals and turning the steering wheel on command
while the drivers received an EEG neuro headset to monitor their brain activity while being trained to remotely drive the car.
According to this Dailymail article, the software can be trained to associate a person thinking about a floating balloon with turning left.
and gestures using their phone camera n
#Using Thought to Control a Robotic Arm The next generation of neuroprosthetics: More natural, effortless, intuitive movement achieved.
and staff at Rancho Los Amigos to control a computer cursor and a robotic arm with his mind.
The arrays are connected by a cable to a system of computers that process the signals,
to decode the brain intent and control output devices, such as a computer cursor and a robotic arm. hese arrays are very small so their placement has to be exceptionally precise,
and it took a tremendous amount of planning, working with the Caltech team to make sure we got it right,
the location, the positioning and how you manage the hardware. Keep in mind that what wee able to dohe ability to record the brain signals
where a computer was attached directly to the ports extending from his skull, to communicate with his brain.
such as controlling a computer cursor; drinking a beverage; making a handshaking gesture; and performing various tasks with the robotic arm.
The implanted device and signal processors used in the Caltech-led clinical trial were the Neuroport Array
and Neuroport Bio-potential Signal Processors developed by Blackrock Microsystems in Salt lake city, Utah. The robotic arm used in the trial was the Modular Prosthetic Limb,
The vessels were detected after Louveau developed a method to mount a mouse meninges the membranes covering the brain on a single slide
To reach their conclusions scientists compared the genetic data of 11,355 patients with schizophrenia against a control group of 16,416 people without the condition.
according to the paper lead author Ram Madabhushi, a postdoc in Tsai laboratory. hen we knocked down this enzyme,
providing the most compelling evidence to date that this is a core transcriptional control mechanism, he says. anticipate that this advance will have broad implications ranging from the basic biology of transcription to pathological mechanisms involved in diseases such as Alzheimer disease
It like erasing a computer disk before you add new data. hen an egg cell is fertilised by a sperm,
Aix-Marseille and the German Mouse Clinic teamed up to investigate the initiation process of dendritic spines.
However, no such tools yet exist for mining the fast-growing mountain of published experimental data in regeneration
Lobo and Levin developed an algorithm that would use evolutionary computation to produce regulatory networks able to volveto accurately predict the results of published laboratory experiments that the researchers entered into a database. ur goal was to identify a regulatory network that could be executed in every cell
so that the head-tail patterning outcomes of simulated experiments would match the published data, Lobo said.
Tufts biologists devloped an algorithm that used evolutionary computation to produce regulatory networks able to volveto accurately predict the results of published research on planarian regeneration.
The algorithm compared the resulting shape from the simulation with real published data in the database.
gradually the new networks could explain more experiments in the database comprising most of the known planarian experimental literature regarding head vs. tail regeneration.
First Regenerative Model Discovered by Artificial intelligence The researchers ultimately applied the algorithm to a combined experimental dataset of 16 key planarian regeneration experiments to determine
After 42 hours, the algorithm returned the discovered regulatory network, which correctly predicted all 16 experiments in the dataset.
Lobo and Levin are trained both in computer science and bring an unusual perspective to the field of developmental biology.
Levin majored in computer science and biology at Tufts before earning his Ph d. in genetics. Lobo earned a Ph d. in the field before joining the Levin lab. The paper represents a successful application of the growing field of obot sciencewhich Levin says can help human researchers by doing much more than crunch enormous datasets quickly. hile
the artificial intelligence in this project did have to do a whole lot of computations, the outcome is a theory of
not only data mining but also inference of meaning of the data. n
#Injectable Device Delivers a Nano-View of the Brain Promise against disease in electronic scaffolds.
the team devised a computer algorithm to process OCT data and, nearly instantaneously, generate a color-coded map with cancer in red and healthy tissue in green. e envision that the OCT would be aimed at the area being operated on,
and the surgeon could look at a screen to get a continuously updated picture of where the cancer is
The data were analyzed then with the help of statistical pattern-recognition methods. The scientists were able to conclude from the various active brain areas which of the three categories (long-known, recently heard,
transmitting their instructions in real time via internet from their home country. By virtue of its video camera
screen and wheels, the robot, located in a laboratory of Ecole polytechnique fédérale de Lausanne (EPFL, Switzerland), was able to film as it moved
while displaying the face of the remote pilot via Skype. The person at the controls,
and the computer, allowing the pilot to rest while navigating. No difference between healthy and disabled subjects In the end, the tests revealed no difference in piloting ability between healthy and disabled subjects.
project called TOBI (Tools for Brain-Computer Interaction which began in 2008. Will robots soon become a fact of daily life for people suffering from a disability?
by adding the concept of wireless communication, the biosensor could be placed in one part of the body,
The video is available at the karolinskainstitutet Youtube pageoriginal Research: Abstract for n organic electronic biomimetic neuron enables auto-regulated neuromodulationby Daniel T. Simon, Karin C. Larsson, David Nilsson, Gustav Burström, Dagmar
When exceeding defined threshold concentrations, biosensor output signals, connected via custom hardware/software, activated local or distant neurotransmitter delivery from the organic electronic ion pump.
applicable for bridging injured sites and active prosthetics. se of Brain MRI Atlases to Determine Boundaries Of age-Related Pathology:
and looked at the longstanding theory that pain is transmitted from the site of injury or inflammation through the nervous system using an immune system cell called microglia.
To study histone composition in mouse nerve cells and related turnover, researchers fed young, post-weaning rodents a special diet containing heavy labeled lysines,
10.1016/j. neuron. 2015.06.014 Abstractcritical Role of Histone Turnover in Neuronal Transcription and Plasticityhighlights 3. 3 displays a unique saturating profile of nucleosome occupancy in postnatal brain
#Detecting Eye diseases With Help of a Smartphone Researchers at the Medical and Surgical Center for Retina developed software that detects eye diseases such as diabetic macular edema using a smartphone.
The system is aimed at general physicians who could detect the condition and refer the patient to a specialist.
The software was developed in collaboration with biomedical engineers from the ITESM and uses the camera of the phone to detect any abnormality in the thickness of the retina. he idea is to detect
and prevent diseases in general practice. We are not replacing the specialist we want to know which patients have a disease
and send the patient to the specialist. sing the software will reduce costs and streamline the Mexican health system.
Software development has been satisfactory and is expected to soon be marketed and incorporated the basic health system.
assistant professor of Biology in the UM College of Arts and Sciences and a senior author of the study. hese data support a critical role for SLC25A46 and mitochondrial dynamics in the establishment and maintenance of neuronal processes.
and active global data exchange were we able to solve this puzzle. r
#Herpes used in cancer treatment Researchers used a modified herpes virus to successfully treat patients with aggressive skin cancer
#Google working with Levis on smart clothes GOOGLE says it working with iconic US jean maker Levi strauss to make clothing from specially woven fabric with touch-screen control capabilities.
The internet titan used its annual developers conference in San francisco to reveal its so-called Project Jacquard
Project Jacquard is in the hands of a small Google team called Advanced Technology and Projects (ATAP),
which is different from the Google (x) lab that develops big-vision innovations such as self-driving cars. e are enabling interactive textiles,
or computer screens with finger strokes on a blue cloth covering a table in the display area behind him. t is just like normal fabric.
and gesture interactivity into any textile using standard, industrial looms, according to Google. Anything involving fabric,
from suits or dresses to furniture or carpet, could potentially have computer touchpad style control capabilities woven.
with miniaturised electronics that can use algorithms to recognise touches or swipes, ATAP says. The data can be sent wirelessly to smartphones or other devices,
enabling actions such as making phone calls or sending messages with brushes of fabric. n our hyper-digital world,
who took part in a Google presentation at the gathering. he work that Google and Levi are embarking upon with Project Jacquard delivers an entirely new value to consumers with apparel that is emotional, aspirational and functional. i
No one had looked at the data in this way before, she said. lot of the people were convinced pretty is was some problem with the imaging,
Ms Loi said the drifting plasma tubes could distort astronomical data, especially satellite-based navigation systems.
As an undergraduate student with no prior background in this, that is an impressive achievement, said Dr Murphy, also of CAASTRO and the School of Physics at the University of Sydney. hen they first saw the data,
Founder Bob Roohparvar, a computer science professor at California State university, likened the technology a tube of toothpaste. f you just squeeze from the top,
Program director for the US NAVY Captain Jeff Dodge likened the upgrade from the MQ-8b based on a smaller airframe to the model aircraft to a brain transplant. e are taking the computer
He is a PC-3 Orion pilot by trade and while he is prepared not to write the obituary for airborne pilots just yet he understands that unmanned systems are booming,
Sensors on the ground at Point Mugu mimic a ship landing system so the chopper simply picks up a radio beam
mission payload operators and a tactical commander who are located in a control room with three large TV screens on the wall
and each operator working a keyboard, mouse and a bank of computer screens. There is no joystick and the system is ly by mousewith the operator using the computer mouse to control the aircraft
even if it is flying thousands of kms away. The future has arrived and as sure as night follows day it will involve fewer airborne pilots and increasing numbers of unmanned aircraft systems.
have seen we the last of piloted aircraft? Probably not, but it will become increasingly difficult in the years ahead to find a military pilot who actually takes to the air i
#Aussie bricklaying robot can build house in two days WORLD, meet your new bricklayer. A robotic, fully-automated machine is being developed in Perth,
It works by creating a 3d computer-aided design (CAD) laying program of a house or structure
while working in the area of computer-controlled machinery and witnessing the shortage of Perth bricklayers that the idea of a bricklaying robot really took hold.
"Our data are the clearest demonstration to date that Octopus bimaculoides skin is intrinsically light-sensitive, "they report.
paper, scissors Next, the team sent information from the implant to a computer, which translated it into instructions to move a separate robotic arm.
This is the worst in a string of threats to the site. Even before this engagement
destroying sites in the process. Before its retreat, the Syrian army evacuated as much of Palmyra's population as possible, together with the museum collections,
many other sites have been damaged in this and other conflicts and even more are harmed by activities such as development and agriculture.
By examining satellite imagery and historic aerial photography, the team looks for and records sites, monitoring the extensive landscape changes of the past 70 years.
working with local heritage agencies to better protect the sites in the future. Others are looking to new technologies to help, such as 3d scanning.
a leader in this field, is scanning as many heritage sites, objects, famous landmarks, and even rock-art sites, as possible.
It is making them internationally accessible online but also creating records that could be used for reconstruction.
Some of these sites are now in areas of great risk, such as Babylon and Mosul in Iraq.
Cyark's goals include scanning 500 heritage sites in the next five years. Such technology is improving exponentially quickly:
new 3d scanning devices are as small as mobile phones, and NGOS hope to deploy them in conflict areas including Syria.
It is also possible to create 3d data even from tourist photographs, often using crowdsourced images.
#Gadgets powered wirelessly at home with a simple Wi-fi router Our homes are tangled a mess of wires and chargers.
Work is under way to use the Wi-fi signals that surround us to power our gadgets.
which modified electrical devices were put in their homes along with a Wi-fi router. Over 24 hours, the devices were powered solely by the router's signal,
which also continued to provide wireless internet access to the home. How was this possible? The energy of the radio waves the router sent out was converted into direct current voltage with a component called a rectifier,
much as solar panels convert light energy into electrical energy. That voltage was boosted then to a useful level by a DC-DC converter (arxiv. org/abs/1505.06815.
The system powered temperature sensors and battery-less low-resolution cameras, and charged standard batteries. The hard part is getting the router to constantly push out enough energy,
says team member Vamsi Talla from the University of Washington in Seattle. When someone is browsing the web,
the Wi-fi signal is active and can be used to power devices. However, when not browsing the signal goes quiet."
"With Wi-fi for communications, you only want to transmit when you have data to send, "Talla says."
"But for power delivery, you want to transmit something all the time. There's a clear mismatch.""To get around this, the team designed software that broadcasts meaningless data across several Wi-fi channels
when no one is using the internet. Small devices could use this as part of an internet of things,
says Ben Potter at the University of Reading, UK.""Where we're heading is to have more sensors in everything around us,
"he says.""Innovations with microchips mean they can run with less power. For that type of application, this is interesting technology."
"The problem is that Wi-fi is never going to provide a very powerful signal. Wi-fi is regulated tightly in many countries the US Federal Communications Commission (FCC), for example, limits the power of a Wi-fi broadcast to 1 watt.
An iphone charger delivers at least 5 watts and has no other demands on its output. One company with a solution is Ossia in Bellevue, Washington.
It has called a system Cota that gets around the FCC regulations by designing a wireless hub that transmits waves at a Wi-fi frequency
but doesn't send a communications signal. The Cota setup can produce up to 20 watts
but would only deliver 1 watt to a single phone. CEO Hatem Zeine says that's enough to charge an iphone 5 several times over in a single day
if it has constant access to the signal.""Unlike Wi-fi, our power signal is unmodulated,
"says Zeine.""It's a continuous wave, there's no message in it.""A receiver chip on the device being charged tells the hub which of Cota's thousands of antennas it is receiving signals from.
Sensors powered by Wi-fi could be used to monitor air quality or the status of systems across a city
Elledge and his colleagues used an international database to look up all viruses known to infect humans around 1000 strains from 206 viral species. Using this information,
"The team used the test to screen blood samples from 569 people from four countries the US, South africa, Thailand and Peru.
Matthews thinks it would be worth extending the screen to animal populations. He envisages screening wild populations of animals thought to be linked to emerging diseases."
whether red light shone into mice's heads using fibre optics can help with Parkinson's disease. A better understanding of how red light affects cells should make it easier to expand its medical uses,
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