Synopsis: Domenii: Ict: Ict generale:


www.bbc.com_technology 2015 00642.txt.txt

#Baidu to launch self-drive car Chinese web giant Baidu will launch its first driverless car in the second half of 2015,

The news, reported by Chinese language website Techweb, will put it head to head with rival Google.

The firm will work with an unnamed car manufacturer, according to Baidu's senior vice president Jin Wang. He made the announcement at the China Cloud computing conference.

The firm has teamed previously up with BMW to develop semi-autonomous car technology. The head of Baidu's deep learning lab Yu Kai has told previously the press that the firm does not agree with Google's view of a completely autonomous car,

looking instead to develop a vehicle that will retain the traditional pedals but give the driver greater freedom.

Baidu's rise in the field of artificial intelligence suffered a setback last week when Stanford university

whether computers can recognise and sort images-banned Baidu from competing for the next year. The web giant was stripped of its 2015 title after it emerged that it broke the rules over how many tests it could run.

Google announced last month that its prototype self-driving cars would take to the public roads this summer around its headquarters in Mountain view, California a


www.bbc.com_technology 2015 00683.txt.txt

#Paris Air Show: Can you print a plane? The new Airbus a350 XWB that is flying daily displays at the Paris Air Show can claim several engineering firsts.

One of these is that it has more 3d printed components than any other aircraft, about 1,

000 on a plane that has gone only just into service. Meanwhile, Raytheon has 3d parts on its missiles,

The 3d components on the A350 XWB are mostly widgets and brackets, formed by fusing layer upon layer of resins in machines that replicate computer-generated 3d models.

Metals and even glass can also be used. So, we're talking about small routine parts here, rather than large structures-at the moment.

In our digitally connected world, a machine could be programmed to start printing even before the aircraft lands.

especially the issue of transmitting secure data across the world, he said. While the holy grail of on-demand supply may be a little way off, John Schmidt,


www.bbc.com_technology 2015 00726.txt.txt

#Hackers steal data using pitta bread Secret encryption keys can be stolen using a cheap gadget so small it could be concealed inside some pitta bread.

Israeli security researchers have demonstrated how to capture radio emissions given off by laptops that inadvertently leak data about the keys.

Before now, grabbing the radio signals was thought to require expensive, bulky equipment. But the four-strong team managed it with cheap components small enough to conceal inside a piece of pocket bread.'

monitors the radio signals given off by laptops when their central processing unit is crunching data. The team discovered that many different operations in a computer,

such as playing a game or decrypting a file, had a characteristic pattern of radio activity.

The differing power demands a CPU made as it worked gave rise to these telltale signals,

when the computer was decrypting a specific email message sent to it by an attacker,

it became possible to work out the key being used to secure data, they said. After demonstrating that the attack worked in the lab,

and algorithms to protect data. Such attacks were established well, Steve Armstrong managing director of Logically Secure, told tech news site The Register."

The team plan to present their work at a technical conference on cryptographic hardware in September r


www.bbc.com_technology 2015 00902.txt.txt

He can now make out the direction of white lines on a computer screen using the retinal implant. Mr Flynn said he was delighted"with the implant

vertical and diagonal lines on a computer screen using the implant. He kept his eyes closed during the test

"It was wonderful to be able to see the bars on the screen with my eyes closed."


www.bbc.com_technology 2015 00949.txt.txt

000 times faster than the Nand flash storage used in memory cards and computers'solid state drives (SSDS).

and is the invention of Intel and Micron. The two US companies predict a wide range of benefits, from speeding up scientific research to making more elaborate video games.

One expert described it as a"huge step forward"."""There are other companies who have talked about new types of memory technology,

Intel is marketing it as the first new class of"mainstream memory "since 1989. 3d XPOINT retains data

when the power is switched off-one of its key advantages over RAM (random access memory), which remains faster.

Rather than pitch it as a replacement for either flash storage or RAM, the company suggests it will be used alongside them to hold certain data"closer"to a processor

so that it can be accessed more quickly than before. Why do need we faster storage? The flash storage in my smartphone and PC seems more than fast enough to view

and record the photos and videos I want. Because there are other situations where using today's storage slows things down

or introduces constraints. So-called"big data"tasks are a particular issue. For example, efforts to sequence and analyse our genes/DNA hold the potential for new and personalised medical treatments.

And it would also prove a boon to video game-makers. At present, level designs are limited by how much data can be stored in the RAM-or, strictly, a type of RAM chip called dynamic RAM (DRAM.

That's why players sometimes have to halt their play while they wait for the machine to load a new section.

But if the data can be loaded more quickly from 3d XPOINT, the developers should, in theory, be able to deliver them bigger, open worlds and a more seamless experience.

"which can store a single bit of data. This represents either a one or a zero in binary code a"selector,

"which allows a specific memory cell to be read or rewritten. Access is controlled by varying the amount of voltage it receives via the wires So,

Nand works by moving electrons back and forth to an isolated part of the transistors known as their"floating gates"to represent the ones and zeros of binary code.

An issue with this technique is that it cannot rewrite single bits of data at a time. Instead, larger blocks of information have to be wiped

"Intel executive Rob Crooke says.""So, you have to shuffle them all around to get one new one in there."

Intel suggests not. Solid state drives-and even slower hard disks-will remain significantly cheaper than 3d XPOINT for some time to come,

so it makes sense to continue using them to store most files. The suggestion is the new technology will normally be used instead as an intermediary step.

Rather than copy data directly from the slower types of storage into RAM, programs will anticipate

what data is likely to be needed and then transfer it in advance to the 3d XPOINT.

why not just use it to replace RAM altogether? RAM's speed advantage over traditional storage has made long it the chip of choice to funnel data directly into processors.

However, because it is relatively expensive to produce, computer makers tend to restrict how much they include.

Each megabyte of 3d Xpoint will certainly be significantly cheaper than the equivalent amount of RAM.

And the new technology has added the advantage of being nonvolatile, meaning it does not"forget"information

But, unfortunately it is still not quite as fast as RAM, and some-but not all-applications need the extra speed the older tech provides.

is there ever an advantage to using 3d Xpoint instead of, rather than in addition to, RAM or flash?

Online gaming companies might want to substitute 3d Xpoint for RAM. At present, the amount of players that can be hosted on a single server is limited by the amount of RAM it contains.

Switching to 3d Xpoint would cause only a small-and possibly unnoticeable-difference to the performance of many of the simpler titles.

One instance when you might want to use the new chips instead of flash would be to store operating system files that are required every time you boot up your machine.

Many users have experienced already faster switch on times on new computers thanks to such files being kept on SSDS rather than disk drives.

"says Intel's marketing director Greg Matson. Whether that proves tempting will depend on exactly what 3d Xpoint costs and just how precious your time is s


www.biologynews.net_ 2015 00053.txt.txt

a postdoctoral fellow in Kipnis'lab. The vessels were detected after Louveau developed a method to mount a mouse's meninges-the membranes covering the brain-on a single slide


www.biologynews.net_ 2015 00067.txt.txt

which makes use of highly selective metal catalysts. Most living organisms have a biological clock with an approximately 24-hour circadian rhythm,

Critical sites on the molecules for bioactivity have been uncovered and both period-lengthening/-shortening molecules have been utilized to investigate the regulation of the clock protein in the body's timekeeping mechanism.

Our original palladium catalysts enable selective installation of functional groups at the desired positions on the heteroaromatic ring."

we found the critical sites on the molecule for rhythm-changing activities, and succeeded in discovering active molecules that lengthens

"We are pleased extremely that C-H activation chemistry has played an important role in finding bioactive sites in KL001 derivatives


www.biologynews.net_ 2015 00076.txt.txt

#Complex, large-scale genome analysis made easier The mset algorithm by Oliver Stegle at EMBL-EBI makes large-scale,

The new algorithm, published in Nature Methods, makes it possible to perform genetic analysis of up to 500,000 individuals-and many traits-at the same time.

and making the best use of data from large cohorts that include hundreds of thousands of individuals."

until now so much computation that it would take a year to run a single complex query."

The researchers tested their algorithm on data from two studies from public repositories, and compared the results with existing state-of-the-art tools.

"Our algorithm can be used to study up to half a million individuals-that hasn't been possible until now.""

The new algorithm provides much-needed methods for genomics, making large-scale, complex analysis a manageable and practical endeavour."


www.biologynews.net_ 2015 00113.txt.txt

and other UC Berkeley researchers publicly debuted a system of beating human heart cells on a chip that could be used to screen for drug toxicity.


www.biologynews.net_ 2015 00140.txt.txt

and whether a tumour is likely to spread to other sites. The findings also open the possibility of new therapies aimed at measuring

"The researchers also looked at the process in a mouse model and found that Grb2 depletion results in the development of multiple tumours in the vicinity of a primary tumour,

Measuring the levels of the proteins in patient tissues followed by database analysis of clinical information from The Cancer Genome Atlas

1. Statistical data reveal that just under 40%of patients with a favourable balance were still alive seven years after samples were taken.

1 and FGFR2 binding sites survived the same length of time. Professor Ladbury said:""From the patient's point of view, the key findings are that these proteins are biomarkers.


www.biologynews.net_ 2015 00148.txt.txt

The data presented suggest that parents abstaining from this practice may cause liver maturation and drug metabolism in their children to develop quiet differently."


www.bionews.org.uk 2015 00048.txt.txt

applied a patented technique called OCT4-based programming to neonatal cord blood and adult blood stem cells.


www.bionews.org.uk 2015 00050.txt.txt

By studying mouse and frog embryos as well as human stem cells they confirmed that the PRDM12 gene is switched normally on during the development of pain-sensing nerve cells.


www.bionews.org.uk 2015 00070.txt.txt

'This molecular data helps us better classify glioma patients, so we can begin to understand who needs to be treated more aggressively


www.biopharma-reporter.com 2015 00200.txt.txt

The professor told in-Pharmatechnologist. com the method can be used to help small and large molecule medicines hone in on their targets. ith all therapies that are used currently particularly cancer the major problem is very little of the drug makes it to the target site.

so they accumulate at the target site. The bubbles last less than ten minutes in the bloodstream before breaking down,

So far the team has had success with the delivery system in mouse models. A clinical study at the University of Oxford is currently investigating using an existing drug in combination with ultrasound but without the bubble technology,


www.biopharma-reporter.com 2015 00322.txt.txt

s an academic lab, our core business is research and not product development. We are testing the substrate with potential commercial partners now. ommercial applicationsthe polymer has application in both the production of cells for drug safety testing


www.biopharma-reporter.com 2015 00323.txt.txt

s an academic lab, our core business is research and not product development. We are testing the substrate with potential commercial partners now. ommercial applicationsthe polymer has application in both the production of cells for drug safety testing


www.biosciencetechnology.com 2015 01057.txt.txt

#New Technology Turns Smartphone into a DNA-Scanning Microscope Researchers at University of California, Los angeles (UCLA) have developed a new technology that turns a smartphone into a DNA-scanning fluorescent microscope.

that utilize consumer devices (especially mobile phones) as a platform for making these measurements in filed settings and resource-limited settings. ere how it works.

and Windows smart application running on the same smartphone. Information is sent then to a remote server in the researchersucla laboratory that measures the length of the DNA molecules.

The data processing can take less than 10 seconds depending on the data connection. Read More: How a Smartphone Camera Can Find Eye Cancertraditional microscopes can do the same thing

but they are bulky, expensive and often unavailable in remote locations. Not only does this technology reduce cost,

and enable telemedicine and mobile health, but there also another angle that makes them attractive,

the microscopes described here are connected all to servers through WIFI or network signals, which make them uite powerfulin terms of labeling results as a function of space

Variety of Usesin general, the smartphone technology being developed at Ozcan lab can be used to perform a number of lab functions,

The team has been able to convert the mobile phone into a sensitive E-coli or giardia detector,

The research, ield-Portable Smartphone Microscopy Platform for Wide-field Imaging and Sizing of Single DNA Molecules, was presented at the Optical Society Conference on Laser and Electro optics (CLEO) 2015 h


www.biosciencetechnology.com 2015 01090.txt.txt

Department of Electrical & Computer engineering, drew on their collective expertise in electrical and biomedical engineering to design a chip that concentrates bacteria in a miniscule spaceust two nanolitres in volumen order to increase the effective concentration of the starting sample.


www.biosciencetechnology.com 2015 01097.txt.txt

#Thermal Imaging Software for Research and Science Applications FLIR Systems'new version 4. 2 of its Researchir thermal imaging software provides researchers and scientists with a powerful tool for viewing,

and sharing the thermal data captured with FLIR Scientific and R&d cameras. Researchir Max version 4. 2 gives users direct access to their Matlab scripts within Researchir for the first time.

This will allow users to access their customized Matlab scripts directly in Researchir for specially-tailored image analysis and processing tasks.

Many useful Matlab functions can now be accessed directly from within the platform. In addition the software also provides FLIR Scientific and R&d thermal camera users with Ultramax file support.

Ultramax is a proprietary image enhancement technology available on FLIR Tsc-Series thermal imaging cameras.

and combines the data into one new image using Researchir 4. 2 software. The result is an impressive quadrupling of thermal imaging pixels,

including full radiometric measurement data. With this facility images that are captured with a 640 x 480 resolution thermal imaging camera can now be transformed to an ultra-sharp 1,

280 x 960 resolution image using FLIR Researchir. With the new version the thermal imaging software can now be activated either with a USB KEY or directly online.

In addition to these new features, FLIR Researchir already includes a number of features for detailed thermal analysis including multiple analysis tools with user defined settings for detailed data examination;

flexible measurement modes; chart, graph and plot reporting and statistical tables allowing users to view detailed image quantitative data for the image analysis tools.

Researchir Max is a version of the software for advanced users who need more analytical functionality in their research.

FLIR Systems,+32 (0) 3665 5100, www. flir. com o


www.biosciencetechnology.com 2015 01123.txt.txt

#Portable Finger-probe Technology Could Help Success of Organ Donations A portable, finger-probe device successfully measured liver function in brain dead adult organ donors,

according to the American Liver Foundation. hese data warrant further exploration in a larger trial in a variety of settings to evaluate acceptable values for donated livers, the study states. t a time


www.biosciencetechnology.com 2015 01127.txt.txt

who worked with Cheng to create better cameras and software for CRYO EM. o it really a huge change in what possible. etter Camera, Better Picture Yet for a long time,

At 400 frames per second, the recording provides enough data so the motion correction software developed in Cheng laboratory can correct for the molecular motion and effectively nblurthe image.


www.biosciencetechnology.com 2015 01145.txt.txt

#British Smartphone Eye-exam App Hoping to Reach Millions of Blind Worldwide Thirty-nine million people are blind across the world.

Now, a British team of eye specialists are hoping to attach the diagnostic tools onto an iphone,

EEK, which stands for portable eye examination kit, is a 3-D-printed attachment that can be attached to an iphone,

the hardware lead for the company. The company has started already taking pre-orders for PEEK,

Other diagnostic uses for smartphones have included using them as low-cost microscopes, in settings from the classroom to medically underserved areas r


www.biosciencetechnology.com 2015 01167.txt.txt

'The team's work has been made possible not only by improvements in the technology for recording brain activity but also the OHBA's approach to the huge amounts of data from dozens of studies,

which enables them to analyse the data faster and more effectively in order to improve our understanding of how the brain works.


www.biosciencetechnology.com 2015 01170.txt.txt

#Data Scientists Find Connections Between Birth Month and Health Columbia University scientists have developed a computational method to investigate the relationship between birth month and disease risk.

The researchers used this algorithm to examine New york city medical databases and found 55 diseases that correlated with the season of birth.

The study was published this week in the Journal of American Medical Informatics Association. his data could help scientists uncover new disease risk factors,

Ph d.,an assistant professor of biomedical informatics at Columbia University Medical center (CUMC) and Columbia Data science Institute.

The researchers plan to replicate their study with data from several other locations in the U s

The new data are consistent with previous research on individual diseases. For example, the study authors found that asthma risk is greatest for July and October babies.

For ADHD, the Columbia data suggest that around one in 675 occurrences could relate to being born in New york in November.

A previous study using Austrian and Danish patient records found that those born in months with higher heart disease ratesarch through Junead shorter life spans. aster computers

a graduate student at Columbia. e are working to help doctors solve important clinical problems using this new wealth of data.


www.biosciencetechnology.com 2015 01173.txt.txt

Louveau discovered the vessels after analyzing the meninges of a mouse. According to reports, the vessels were hidden very well


www.biosciencetechnology.com 2015 01235.txt.txt

and they decided to collect samples from groundwater at a remediation site in Rifle, Colorado..

probing not only the acidic pools in abandoned mines and the contaminated groundwater at the Superfund cleanup site in Colorado,


www.biosciencetechnology.com 2015 01251.txt.txt

painless patch could lower blood glucose in a mouse model of type 1 diabetes for up to nine hours.

the researchers inserted a core of solid insulin and enzymes specially designed to sense glucose.

The researchers tested the ability of this approach to control blood sugar levels in a mouse model of type 1 diabetes.


www.biosciencetechnology.com 2015 01256.txt.txt

In mouse brains, as in human brains, adult neural stem cells reside on the walls of cavities called ventricles,

Alvarez-Buylla and his team traced the development of mouse adult neural stem cells back to their embryonic progenitors.

when the mouse embryo is between 13 and 15 days old, uite early in embryonic brain development, said Alvarez-Buylla,

the scientists found that the mouse adult neural stem cells they studied are derived from embryonic neural stem cells that produce neurons in entirely different parts of the brain. his means that, somehow,

mouse brains have long been accepted as excellent basic research models for the human brain, he said.


www.biosciencetechnology.com 2015 01285.txt.txt

#SAPH-ire Helps Scientists Prioritize Protein Modification Research Researchers have developed a new informatics technology that analyzes existing data repositories of protein modifications

SAPH-ire collects non-redundant and experimentally verified PTM data across all known members of a protein family.

"The PTM hotspots are projected onto 3d protein structures available in the Protein Data Bank (PDB),

what might be considered the meta-data that exists in the public domain, collected all the PTMS and all the structures,

The Georgia Tech researchers are also creating a database that other protein scientists can query to help them identify

and they expect to see their program become part of informatics systems used to analyze large volumes of proteomics data emerging from labs around the world."

and context to all the data that is being produced about PTMS, "Torres said.""Connecting SAPH-ire to other programs that convert mass spec data into actual PTM data could provide immediate biological relevance and prioritization for biochemists and others.

It is likely to expose many new and unsuspected relationships between protein modification, protein structure and function."


www.biosciencetechnology.com 2015 01291.txt.txt

users will benefit from continuous maximum filter performance. Consistent results, ease of use, tremendous speed and linear scalability are the key characteristics of the technology.


www.biosciencetechnology.com 2015 01293.txt.txt

and looked at the longstanding theory that pain is transmitted from the site of injury or inflammation through the nervous system using an immune system cell called microglia.


www.biosciencetechnology.com 2015 01305.txt.txt

The therapeutic viral vector to be used in each of these injections is prepared at the UNC Vector Core Human Applications Laboratory.

Bringing such path-breaking treatments to children affected by neurogenetic disorders is really the core mission of our team here at the NINDS


www.biosciencetechnology.com 2015 01307.txt.txt

OGT Cytosure Interpret Software is used for data analysis, including updated features, such as the B-allele frequency plot, that have been optimized for the identification of biologically relevant genomic variants in tumor samples s


www.biosciencetechnology.com 2015 01332.txt.txt

In mouse models, delivering sirna into cancer cells inhibited the expression of Twist, which in turn reduced epithelial-mesenchymal transition


www.biosciencetechnology.com 2015 01356.txt.txt

noninvasive reath testthey believe will have the potential to screen for a variety of diseases, including diabetes, infections and cancers.

and improve the analysis of data coming out of the device, he said. Although there is much research needed in breath analysis,


www.biosciencetechnology.com 2015 01358.txt.txt

#Bacterial Computing The riendlybacteria inside our digestive systems are being given an upgrade, which may one day allow them to be programmed to detect and ultimately treat diseases such as colon cancer and immune disorders.

These basic computing elements will allow the bacteria to sense, memorize, and respond to signals in the gut,

such strains are only found at low levels within the human gut, according to Timothy Lu, an associate professor of biological engineering and of electrical engineering and computer science,

In addition, more advanced genetic computing circuits could be built upon this genetic toolkit in Bacteroides to enhance their performance as noninvasive diagnostics and therapeutics. or example,


www.biosciencetechnology.com 2015 01386.txt.txt

and other UC Berkeley researchers publicly debuted a system of beating human heart cells on a chip that could be used to screen for drug toxicity.


www.biosciencetechnology.com 2015 01416.txt.txt

a clinical stage biopharmaceutical company which owns the core T-cell receptor technology and funded the study.


www.biosciencetechnology.com 2015 01427.txt.txt

Dr. Hauser and his team used a mouse model of Pseudomonas aeruginosa (PA) pneumonia to examine how the bacterium uses its secretion system to inject a toxin, called Exos, into cells.


www.biosciencetechnology.com 2015 01452.txt.txt

Bolivia and Belgium examined data on 97 leishmaniasis patients. These were gathered through a project on drug resistance,


www.biosciencetechnology.com 2015 01465.txt.txt

#Software Turns Smartphones into Tools for Medical Research Jody Kearns doesn't like to spend time obsessing about her Parkinson's disease.

Yet since she enrolled in a clinical study that uses her iphone to gather information about her condition,

She taps the phone's screen in a certain pattern, records a spoken phrase and walks a short distance while the phone's motion sensors measure her gait."

'"Smartphone apps are the latest tools to emerge from the intersection of health care and Silicon valley,

and doctors together online, applying massive computing power to analyze DNA and even developing ingestible"smart"pills for detecting cancer.

More than 75,000 people have enrolled in health studies that use specialized iphone apps, built with software Apple Inc. developed to help turn the popular smartphone into a research tool.

Once enrolled, iphone owners use the apps to submit data on a daily basis, by answering a few survey questions

or using the iphone's built-in sensors to measure their symptoms. Scientists overseeing the studies say the apps could transform medical research by helping them collect information more frequently and from more people, across larger and more diverse regions,

than they're able to reach with traditional health studies. A smartphone"is a great platform for research,

"said Dr. Michael Mcconnell, a Stanford university cardiologist, who's using an app to study heart disease."

researchers also say a smartphone's microphone, motion sensors and touchscreen can take precise readings that,

in some cases, may be more reliable than a doctor's observations. These can be correlated with other health or fitness data and even environmental conditions, such as smog levels, based on the phone's GPS locater.

Others have had similar ideas. Google Inc. says it's developing a health-tracking wristband specifically designed for medical studies.

Researchers also have tried limited studies that gather data from apps on Android phones. But if smartphones hold great promise for medical research

experts say there are issues to consider when turning vast numbers of people into walking test subjects.

The most important is safeguarding privacy and the data that's collected, according to ethics experts.

In addition, researchers say apps must be designed to ask questions that produce useful information, without overloading participants

Study organizers also acknowledge that iphone owners tend to be more affluent and not necessarily an accurate mirror of the world's population.

Apple had created previously software called Healthkit for apps that track iphone owners'health statistics and exercise habits.

Senior vice president Jeff Williams said the company wants to help scientists by creating additional software for more specialized apps

using the iphone's capabilities and vast user base-estimated at 70 million or more in North america alone."

"This is advancing research and helping to democratize medicine, "Williams said in an interview. Apple launched its Researchkit program in March with five apps to investigate Parkinson's, asthma, heart disease, diabetes and breast cancer.

For scientists, a smartphone app is a relatively inexpensive way to reach thousands of people living in different settings and geographic areas.

"Smartphones also offer the ability to collect precise readings, Dorsey added. One test in the Parkinson's study measures the speed at

which participants tap their fingers in a particular sequence on the iphone's touchscreen. Dorsey said that's more objective than a process still used in clinics,

Some apps rely on participants to provide data. Elizabeth Ortiz, a 48-year-old New york nurse with asthma, measures her lung power each day by breathing into an inexpensive plastic device.

who said she already used her iphone"constantly"for things like banking and email.""I figured that participating would help my family and friends,

In the future, researchers might be able to incorporate data from participants'hospital records, said Mcconnell. But first, he added,

they must build a track record of safeguarding data they collect.""We need to get to the stage where we've passed the privacy test

and remove identifying information from other data that's collected. Apple says it won't have access to any data or use it for commercial purposes.

Some studies will always require in-person interaction or supervision by a doctor, experts say. But by reaching more people and gathering more data, advocates say smartphone apps can help doctors answer more subtle questions about a disease."

"Diseases like asthma are complicated very. They're not caused by a single gene or environmental influence,"said Eric Schadt,

a genomics professor who's using an iphone app to study asthma at New york's Icahn School of medicine at Mount sinai."


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