"Moreover, most functional screens are carried out in mouse ESCS. The only functional screen on human ESCS was published in 2010 from our laboratory at the GIS.
This latest study was performed also on human ESCS, making it more clinically relevant than studies using mouse ESCS."
"Co-lead author Research Fellow Dr Liang Hongqing at GIS'Stem Cell and Regenerative Biology added,
#New research may enhance display, LED lighting technology Recently, quantum dots (QDS)--nano-sized semiconductor particles that produce bright, sharp,
color light--have moved from the research lab into commercial products like high-end TVS, e readers, laptops,
and photonic crystal technology, could lead to brighter and more efficient mobile phone, tablet, and computer displays, as well as enhanced LED lighting.
They then used electrohydrodynamic jet (e-jet) printing technology to precisely print the QD-embedded polymers onto photonic crystal structures.
and more efficient displays.""Since screens consume large amounts of energy in devices like laptops, phones,
and tablets, our approach could have a huge impact on energy consumption and battery life, "she noted."
"If you start with polarized light, then you double your optical efficiency, "See explained.""If you put the photonic crystal-enhanced quantum dot into a device like a phone or computer,
then the battery will last much longer because the display would only draw half as much power as conventional displays."
"To demonstrate the technology, See fabricated a novel 1mm device (aka Robot Man) made of yellow photonic crystal-enhanced QDS.
and evaluated the penetration capability by using mouse brains in vitro/in vivo. In addition, as an actual needle application, we demonstrated fluorescenctce particle depth injection into the brain in vivo,
such as Microsoft's Kinect controller for video games, have become widely used 3-D sensors. Now, a new imaging technology invented by Carnegie mellon University and the University of Toronto addresses a major shortcoming of these cameras:
if other camera hardware is used, the mathematical framework developed by the team can compute energy-efficient codes that optimize the amount of energy that reaches the camera.
In addition to enabling the use of Kinect-like devices to play videogames outdoors, the new approach also could be used for medical imaging,
"The study links a family of enzymes--molecules that act as biological catalysts--known as polyketide synthases (PKS) directly to a complex series of chemical reactions that ultimately add sulfur to leinamycin, a member of the polyketide family of natural products."
rather than just relying on traditional chemical screens, "says Hubbard, an assistant professor of pharmacology in the University of Alberta's Faculty of medicine & Dentistry."
Much like how a computer programmer edits computer code, scientists could one day replace a person's broken
If the core of a nuclear reactor gets too hot, bubbles in the cooling water can suddenly coalesce to form a vapor film that limits further heat transfer
Their coordinates in hand, scientists can then tell the computer-controlled electron beam lithography tool to place any structure the application calls for in its proper relation to the quantum dots,
#Fiber-like light emitting diodes for wearable displays A research team at Korea Advanced Institute of Science
and Technology (KAIST) has developed fiber-like light emitting diodes, applicable to wearable displays. Professor Kyung-Cheol Choi and his research team from the School of Electrical engineering at KAIST have developed fiber-like light emitting diodes,
which can be applied in wearable displays. The research findings were published online in the July 14th issue of Advanced Electronic Materials.
Traditional wearable displays were manufactured on a hard substrate, which is attached later to the surface of clothes.
Such technique has posed limitations in applying it for wearable displays because inflexible displays were not adequate in practice,
and the characteristics of fabric were ignored. For a solution, the research team discarded the tradition of creating light emitting displays on a plane board.
Instead, they focused on fibers, a component of fabrics, and developed a fiber-like light emitting diode that has the characteristics of both fabrics and displays.
The essence of this technology, the dip coating process, is to immerse and extract a three dimensional (3-D) board that looks like a thread in a solution.
The researchers said that this technology would accelerate the commercialization of fiber based wearable displays
"Our research will become a core technology in developing light emitting diodes on fibers, which are fundamental elements of fabrics.
we can lower the barrier of wearable displays to enter the market.""The first author of the published paper, Seon-Il Kwon, added,
"This technology will eventually allow the production of wearable displays to be as easily as making clothes
In some ways it's making genetic testing open source.""The development of the new test is an example of Stanford Medicine's focus on precision health,
#New optical chip lights up the race for quantum computer The microprocessor inside a computer is a single multipurpose chip that has revolutionized people's life,
and performing otherwise intractable mathematics that aren't possible for super computers. Arraysince before Newton held a prism to a ray of sunlight and saw a spectrum of colour,
much like they operate any other piece of software on a computer. They no longer need to convince a physicist to devote many months of their life to painstakingly build
and reduce costs The process replaces the chemical tablets phosphine and methyl bromide, which are toxic and carcinogenic,
The physicochemical expert explains that the common spraying method is used in doses of four tablets of phosphine per ton of grain."
making a tea, tablets, capsules or powders that can be added to the water. We hope to get the patent later this year
and their design was done traditionally by manufacturing but now, with 3d printing, computer manufacturing and more laser technology,
Then, using a complex computer algorithm, they determined the responses of all possible combinations of the segments.
and converts'breath signals'into words using pattern recognition software and an analogue-to-digital converter.
and expensive mouse avatars that are created by injecting human tumor cells into mice.""This is really the first time that it's been demonstrated that you can use a rapid methodology like this to spatially define cancer cells and macrophages,
What sets the team's model apart from mouse avatars and hard plastic plates is that it can replicate much more accurately the sizes and shapes of the microenvironment within the patient's problem area.
By modeling this process on a computer, the researchers found a good match with the experimental results.
Another key advance is the use of active, inexpensive catalysts for fuel production. The photoanode requires a catalyst to drive the essential water-splitting reaction.
Rare and expensive metals such as platinum can serve as effective catalysts, but in its work the team discovered that it could create a much cheaper,
This catalyst is among the most active known catalysts for splitting water molecules into oxygen
At its core, however, is a rule known as Heisenberg's uncertainty principle. This states that in any situation in which a particle has linked two properties,
#DNA-guided 3-D printing of human tissue is unveiled Arraythere are few limits to the tissues this technology can mimic,
showing that samples of brain tissue from two human MSA patients were able to transmit the disease to a mouse model for Parkinson's disease,
and that infected mouse brain tissue could itself spread the disease to other mice. The discovery that alpha-synuclein prions can transmit MSA raises a public health concern about treatments
in contrast to the 120 days it takes for the disease to spread to mouse models."
"You have to let the mouse models develop for such a long time that research on cures is really slow to progress.
such as smart watches, fitness trackers and health monitors. All of these devices will need to communicate information with each other.
The defect gene was identified through extensive computer analysis and Ph d. candidate Tuva Barøy subsequently worked with collaborators in The netherlands to find out how the gene defect affects cell function.
shift work, jet lag and even the blue-tinged light emitted by cell phones and tablets. Typically, sleep researchers have a hard time studying sleep deprivation and the circadian cycle separately,
and specificity to detect malaria with both ios -and Android-based devices and requires less user expertise than traditional microscopy,
Coté says. That user friendly aspect, coupled with the system's portability and expected low cost of about $10 per unit, makes it an easily adoptable technology in low-resource areas ravaged by malaria,
The technology was among the top award winners in the Texas instruments Innovation Challenge this past summer.
The technology, developed in collaboration with Texas instruments, represents a growing interest in the development of high-tech sign language recognition systems (SLRS) but unlike other recent initiatives,
and send information via Bluetooth to an external laptop that performs complex algorithms to interpret the sign
and display the correct English word for the gesture. As Jafari continues to develop the technology,
he says his team will look to incorporate all of these functions into one wearable device by combining the hardware and reducing the overall size of the required electronics.
so that he or she can understand what is being signed simply by reading the screen of their own device.
In addition, because many labs use their own software to examine CNVS, there is little consistency in how researchers analyze their results.
Schatz and his team named their software after the gingko tree which has documented many well therapeutic benefits."
Larger-scale applications could combine metal or plastic panels with hinges. Next, the researchers plan to explore new combinations of tubes with different folding angles to build new structures.
These technologies could make it possible to perform calculations that are far beyond the capabilities of today's computers.
what are called CRISPR libraries instead of RNAI screens.""This is a major finding with translational implications for this infection that causes so many deaths worldwide,
A team of engineers and an artist developed an array of small solar cells that can tilt within a larger panel
from the standpoint of the person who's putting this panel up, nothing would really change,
"When the panel is at an angle, it looks smaller. By designing an array that tilts
and Shtein how to create them in paper using a plotter cutter. Lamoureux then made more precise patterns in Kapton,
it is almost as good as a conventional single-axis tracker, offering a 36 percent improvement over a stationary panel.
Conventional trackers produce about 40 percent more energy than stationary panels under the same conditions,
Using computer-generated model speeds up the drug discovery process The new drug-like compounds discovered by Vogel
and her co-authors offer hope that using a computer-generated P-gp model, explained here http://bit. ly/1lvmr7a,
Researchers virtually screened 15 million drug-like compounds via SMU supercomputer The SMU researchers discovered the three hit compounds after virtually screening more than 15 million small drug-like compounds made publically available
San francisco. Using SMU's Maneframe high performance computer, Wise ran the compounds through a computer-generated model of P-gp.
The virtual model, designed and built by Wise, is the first computational microscope of its kind to simulate the actual behavior of P-gp in the human body,
Using computer-generated model speeds up the drug discovery process The new drug-like compounds discovered by Vogel
and her co-authors offer hope that using a computer-generated P-gp model, explained here http://bit. ly/1lvmr7a,
Researchers virtually screened 15 million drug-like compounds via SMU supercomputer The SMU researchers discovered the three hit compounds after virtually screening more than 15 million small drug-like compounds made publically available
San francisco. Using SMU's Maneframe high performance computer, Wise ran the compounds through a computer-generated model of P-gp.
The virtual model, designed and built by Wise, is the first computational microscope of its kind to simulate the actual behavior of P-gp in the human body,
One purpose of this experiment was to show we could integrate bacterial catalysts with semiconductor technology.
especially the catalysts that convert water and carbon dioxide into sugars at room temperatures.""This is not about mimicking nature directly
One purpose of this experiment was to show we could integrate bacterial catalysts with semiconductor technology.
especially the catalysts that convert water and carbon dioxide into sugars at room temperatures.""This is not about mimicking nature directly
according to the Active Bacterial Core surveillance report by the Centers for Disease Control and Prevention.
therefore very important and contribute to the outlook where only five out of ten patients will survive for at least five years."
By combining Scales with Abscale--a variation for immunolabeling--and Chemscale--a variation for fluorescent chemical compounds--they generated multicolor high-resolution 3d images of amyloid beta plaques in older mice from a genetic mouse
As well as offering new opportunities for industry, it will stimulate the search for even better basic catalysts
Now, a team led by Wyss Institute Core Faculty member David Mooney, Ph d.,has developed a new strategy--embedding stem cells into porous,
#Building the electron superhighway TV screens that roll up. Roofing tiles that double as solar panels. Sun powered cell phone chargers woven into the fabric of backpacks.
photorealistic computer simulations allowing university and high-school students as well as the general public to virtually access unique instruments."
The engaging software was developed together with university and high-school students and was tuned fine by periodic didactic input.
In addition to Kang and Lerner, authors of the study,"Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signaling,"were Bo-Ram Bang, Kyung Ho Han
The oviductosomes from a female mouse were labeled pre with a fluorescent dye and incubated together with the sperm.
and printer right at the hospital to create custom nerve guides right on site to restore nerve function."
The computational elements in Safepay consist of a mobile device and a server which distributes disposable credit card numbers.
The physical entity is the magnetic credit card chip controlled by a mobile application inside a customer's mobile device.
The paper outlines the overall architecture and server-side deployment model the design of Safepay, prototype implementation and security analysis. Here's how it works:
which communicates with the bank server. During transactions, the mobile application acquires disposable credit card numbers from the bank server,
generates a wave file, plays the file to generate electrical current, and then drives the magnetic card chip via an audio jack
and print concentrated viscoelastic inks that allow for the simultaneous control of composition and geometry during printing.
The research was led by Jennifer A. Lewis, the Hansjörg Wyss Professor of Biologically Inspired Engineering at the Harvard John A. Paulson School of engineering and Applied sciences (SEAS) and a Core Faculty member at the Wyss Institute for Biologically Inspired Engineering
and re-scan it--repeating the process until the desired spatial resolution is achieved--before combining the data from each scan using a computer algorithm.
This is a crucial step in creating a new generation of foldable electronics--think a flat-screen television that can be rolled up for easy portability--and implantable medical devices.
The researchers used mouse embryonic fibroblast cells to determine biocompatibility; that, along with the fact that the stretchability of gold nanomesh on a slippery substrate resembles the bioenvironment of tissue
and totally redesigned its core to repurpose its infectious capabilities into a safe vehicle for delivering vaccines
a particularly complex BMC that requires a series of protein-protein interactions involving at least six gene products to form a metabolic core that takes CO2 out of the atmosphere and converts it into sugar.
a two-drug combination discovered by UF Health researchers that inhibits tumors and kills cancer cells in mouse models.
Researchers then tested its effectiveness on human pancreatic cells that had been implanted in mouse models. Daily doses of the compound reduced tumor volume by about 50 percent after 25 days, they found.
In testing on two mouse cell lines, the drug combination reduced the viability of cancer cells by about 50 percent
This is an important step on the way towards optical computers. Phase change materials that change their optical properties depending on the arrangement of the atoms allow for the storage of several bits in a single cell.
With optical elements, computers can work more rapidly and more efficiently. Optical fibers have long since been used for the transmission of data with light.
But on a computer, data are processed still and stored electronically. Electronic exchange of data between processors and the memory limits the speed of modern computers.
To overcome this so-called Von neumann bottleneck, it is not sufficient to optically connect memory and processor,
as the optical signals have to be converted into electric signals again. Scientists, hence, look for methods to carry out calculations and data storage in a purely optical manner.
but also with latest processors,"Professor Harish Bhaskaran of Oxford university adds. The new memory can store data for decades even
Permanent all-optical on-chip memories might considerably increase future performance of computers and reduce their energy consumption.
Against the backdrop of healthy mouse tissue, rogue metastatic cells from the human tumor stick out like flares.
The researchers developed a new method using flow cytometry that let them capture individual human metastatic cancer cells traveling through the mouse's blood
Whereas 44 percent of control mice (11 of 25) developed secondary tumors within four weeks, researchers could only find metastatic cells in one drug-treated mouse (4 percent.
The respondent is shown an object (for example, a dog) on a computer screen, and the second participant,
With the click of a mouse, the inquirer sends a question and the respondent answers"yes"or"no"by focusing on one of two flashing LED LIGHTS attached to the monitor,
which flash at different frequencies. A"no"or"yes"answer both send a signal to the inquirer via the Internet
or by the brain signal transmission being interrupted by hardware problems.""While the flashing lights are signals that we're putting into the brain,
on brain-computer interfaces that enable people to activate devices with their minds. In 2011, Rao began collaborating with Stocco
Traditional perovskites are typically metal-oxide materials that display a wide range of fascinating electromagnetic properties,
were randomised to receive either 60 mg a day of cabozantinib in tablet form, or 10 mg a day of everolimus, also in tablet form.
Their disease had to have progressed within six months of receiving prior treatment with VEGFR tyrosine kinase inhibitor (TKI) therapy.
Because we use essentially the same device technology as existing computer chips, we believe it will be much easier to manufacture a full-scale processor chip than for any of the leading designs,
which rely on more exotic technologies.""This makes the building of a quantum computer much more feasible,
since it is based on the same manufacturing technology as today's computer industry, "he added. The advance represents the final physical component needed to realise the promise of super-powerful silicon quantum computers,
which harness the science of the very small--the strange behaviour of subatomic particles--to solve computing challenges that are beyond the reach of even today's fastest supercomputers.
In classical computers, data is rendered as binary bits, which are always in one of two states:
"The silicon chip in your smartphone or tablet already has around one billion transistors on it, with each transistor less than 100 billionths of a metre in size,"said Dr Menno Veldhorst,
"He said that a key next step for the project is to identify the right industry partners to work with to manufacture the full-scale quantum processor chip.
Such a full-scale quantum processor would have major applications in the finance, security and healthcare sectors, allowing the identification
Virginia--a liquid-cooled FPGA was operated using a custom processor architecture provided by Altera. With a water inlet temperature of approximately 20 degrees Celsius and an inlet flow rate of 147 milliliters per minute
However, the same technology could also be used to cool CPUS, GPUS and other devices such as power amplifiers,
'We were able to understand this effect by performing extensive numerical computer simulations of the electronic properties
Preclinical studies using mouse models of bladder cancer have demonstrated the efficacy of the mycobacterium M. brumae in the treatment of this disease.
#Groundbreaking computer program diagnoses cancer in two days In by far the majority of cancer cases, the doctor can quickly identify the source of the disease, for example cancer of the liver, lungs, etc.
and created a new diagnostic technology based on advanced self learning computer algorithms which--on the basis of a biopsy from a metastasis--can with 85 per cent certainty identify the source of the disease
The pattern of mutations is analysed in a computer program which has been trained to find possible primary tumour localizations.
and represent it on a computer screen. In this article, Inserm researchers, using MRI, have succeeded in detecting natural shear waves in the brain using computational techniques borrowed from seismologists and known as"noise correlation."
#New graphene based inks for high-speed manufacturing of printed electronics A low-cost, high-speed method for printing graphene inks using a conventional roll-to-roll printing process,
the first time that graphene has been used for printing on a large-scale commercial printing press at high speed.
"Being able to produce conductive inks that could effortlessly be used for printing at a commercial scale at a very high speed will open up all kinds of different applications for graphene and other similar materials.""
which is in line with commercial production rates for graphics printing, and far faster than earlier prototypes.
it could also initiate entirely new business opportunities for commercial graphics printers, who could diversify into the electronics sector."
and the Cambridge area in particular, has always been strong in the printing sector, but mostly for graphics printing and packaging,"said Hasan, a Royal Academy of Engineering Research Fellow and a University Lecturer in the Engineering Department."
"We hope to use this strong local expertise to expand our functional ink platform. In addition to cheaper printable electronics, this technology opens up potential application areas such as smart packaging and disposable sensors,
But there's a step needed before optical connections can be integrated into telecommunications systems and computers:
Then, using a computer-controlled light projector, the team was able to control the speed of the cardiac waves,
In the short term, the ability to provide fine control means that researchers are able to carry out experiments at a level of detail previously only available using computer models.
what one can do in a computer model, except here it was done in real heart cells, in real time.'
"Zhang, lead authors Lucia Wu and J. Sherry Wang and their colleagues have written software to help researchers design their own probes.
Interestingly, a subsequent challenge with a lethal strain of mouse malaria parasite in these vaccinated animals showed considerable protection against malaria.
When you plug a device like a computer into the wall, electronic circuitry in the computer's power supply converts the AC oscillations into direct current (DC) that the device can use.
The AC to DC conversion is done by an electronic component called a rectifier. Similarly, electromagnetic oscillations in the air can be turned into DC current by a device called a rectenna,
Park's team uses software to analyze how the nanoscale topology of a surface--its bumps
The researchers also used computer modeling to design a bowtie-shaped antenna that would effectively capture the enhanced thermal emission.
reflectors, and USB detectors, combined with the all-plastic housing and lenses will allow for future versions of the prototype to be mass-produced d
and Ear/Harvard Medical school and Boston University have shown successfully neuroprotection in a Parkinson's mouse model using new techniques to deliver drugs across the naturally impenetrable blood-brain barrier.
computers and even gym facilities,"said Egidijus Auksorius, postdoctoral researcher, The Langevin Institute. Despite the widespread use of commercial fingerprint sensors, problems with the devices persist,
An LVAD is composed of a computer controller, a power pack and a reserve power pack that remain outside the body
#New research paves the way to begin developing a computer you can control with your mind A team of researchers led by Angelika Lingnau, from the Department of psychology at Royal Holloway,
and could be the first step in the development of brain-computer interfaces. Dr. Lingnau and her team used functional magnetic resonance imaging (fmri)
In mouse models of human glioblastoma, one molecule they found shrank the average tumor size by half.
as well as the San diego Supercomputer Center and Department of Neurosciences at UC San diego.""But we addressed this challenge
Canada and high-performance workstations at the San diego Supercomputer Center to run the search. With this approach, the researchers identified a few molecules that would likely fit the OLIG2 interaction.
The most effective of these candidate drug molecules, called SKOG102, shrank human glioblastoma tumors grown in mouse models by an average of 50 percent."
The discovery of magnetoresistance paved the way for magnetic field sensors used in hard disk drives and other devices,
We found that a bilayer structure of graphene and boron nitride displays an extremely large response with magnetic fields.
and finding applications as thermal switches, hard drives and magnetic field sensors. Our technology can even be applied to flexible applications,"added Assoc Prof Yang.
a portable USB-powered film scanner to image the test strips; and a portable computer for real-time data analysis.
The entire system can be carried in a small briefcase, handbag or laptop case, and requires just one operator with minimal training to conduct the test within 15 minutes--with no need for additional equipment or instruments.
One of the remarkable features of the lab-in-a-briefcase is that it uses whole blood without the need for any sample preparation--a previously challenging task outside of a laboratory setting.
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