and where one can place a saliva sample showing the results through a software. The director of FEMSA Biotechnology Center mentions that he considered using the camera phone to detect the marker in saliva,
By implementing Imsane as an open source MATLAB toolbox the KITP researchers provide a practical, highly accessible tool for data reduction and analysis of layered tissues.
which exceeds the hard drive capacity of most computers and would take 100 hours to transfer with a good Internet connection,
"The program is especially useful for biologists who otherwise would have to acquire the skillset and hardware to handle large data
Scientists have experimented for decades with a class of catalysts known as zeolites that transform alcohols such as ethanol into higher-grade hydrocarbons.
Instead, an energy-producing"hydrocarbon pool"mechanism allows the zeolite catalysts to directly produce longer hydrocarbon chains from the original alcohols."
#Researchers develop 3-D printing method for creating patient-specific medical devices A team of researchers at Northeastern University has developed an innovative 3-D printing technology that uses magnetic fields to shape composite materials
"Others have used composite materials in 3-D printing, says Joshua Martin, the doctoral candidate who helped design
Erb and Martin's 3-D printing method aligns each minuscule fiber in the direction that conforms precisely to the geometry of the item being printed."
"The magnets are the defining ingredient in their 3-D printing technology. Erb initially described their role in the composite-making process in a 2012 paper in the journal Science.
They then apply ultralow magnetic fields to individual sections of the composite material--the ceramic fibers immersed in liquid plastic--to align the fibers according to the exacting specifications dictated by the product they are printing."
layer by layer, using a computer-controlled laser beam that hardens the plastic. Each six-by-six inch layer takes a mere minute to complete."
#3-D printed'building blocks'of Life scientists have developed a 3-D printing method capable of producing highly uniform'blocks'of embryonic stem cells.
"Our next step is to find out more about how we can vary the size of the embryoid body by changing the printing and structural parameters,
#3-D-Printed Device Helps Computers Solve Cocktail-party Problem Artificial-intelligence researchers have struggled long to make computers perform a task that is simple for humans:
In their proof-of-concept study, they sent light from the LED through an optical fiber to stimulate neurons in mouse brain slices.
The core of the project involves recycling local plastic into versatile locksduring volunteer workshops which are used then to build objects such as benches, planters and stages for use within the community.
CITIES have created various open source resources to help people launch further schemes in other neighborhoods. What other forms of waste can also be reused in educational, community-building ways y
The Heattech Mirror visually displays the wearer body temperature rising in the mirror. The smart mirror is connected to a thermal camera
390 gram (0. 9-pound) Robohon sports a 2-inch touchscreen, a quad-core CPU, and can connect to 3g, LTE,
A Sharp spokesperson tells Tech in Asia that the robot has an original operating system that not based on Android (the company consumer smartphones have traditionally been powered by Google OS.
The company uses both hardware and software solutions to achieve this. Its system, bearing the catchy name Jamsdefender, combines active noise cancellation, digital volume normalization,
On the software side a method the company calls digital decibel equalizer technology normalizes the volume at a safe level.
The target was quite modest, especially for a hardware campaign, but the team says it had to balance estimated costs with a realistic crowdfunding target that wouldn deter backers by appearing too lofty.
The scientists analyzed the process using computer simulations to determine the best method of injecting the material
It a step towards enabling computers to process information hundreds of times faster than today machines.
Computers currently shuttle information around using electricity traveling down nanoscale metal wires. Although inexpensive and easy to miniaturize,
At a maximum voltagelose to the voltages used in today computer chipshe gap narrows, slowing the plasmons.
or suppress infection in mouse and nonhuman primate models of HIV. But these animal models are very rough approximations of human infections,
and being hooked up to a battery about the size of a small laptop computer whenever they want to go out and about.
which computers are turned loose on huge data sets to look for patterns. To make machine-learning applications easier to build,
computer scientists have begun developing so-called probabilistic programming languages, which let researchers mix and match machine-learning techniques that have worked well in other contexts.
At the Computer Vision and Pattern Recognition conference in June MIT researchers will demonstrate that on some standard computer-vision tasks,
short programs less than 50 lines long written in a probabilistic programming language are competitive with conventional systems with thousands of lines of code. his is the first time that wee introducing probabilistic programming in the vision area,
By the standards of conventional computer programs those odelscan seem absurdly vague. One of the tasks that the researchers investigate,
and Pushmeet Kohli of Microsoft Research Cambridge. For their experiments, they created a probabilistic programming language they call Picture,
Even though their computers were painfully slow by today standards, the artificial intelligence pioneers saw that graphics programs would soon be able to synthesize realistic images by calculating the way in
Kulkarni and his colleagues considered four different problems in computer vision, each of which involves inferring the three-dimensional shape of an object from 2-D information.
Built into Picture are several different inference algorithms that have fared well on computer-vision tasks.
if the learning machinery is powerful enough to learn different strategies for different tasks. icture provides a general framework that aims to solve nearly all tasks in computer vision,
who was involved not in the work. t goes beyond image classification the most popular task in computer vision
and tries to answer one of the most fundamental questions in computer vision: What is the right representation of visual scenes?
an approach that is not commonly used for this kind of screen. nitially, the screening results appeared to not have positive hits,
#Computer-Designed Rocker Protein Worlds First To Biomimic Ion Transport For the first time, scientists recreated the biological function of substrate transportation across the cell membranes by computationally designing a transporter protein.
Simulations on the Stampede supercomputer of the Texas Advanced Computing Center (TACC) bridged the gap between the drawing board
The molecular dynamics simulations were about a microsecond of aggregate simulation time with classical force fields using the NAMD software program.
The computer allocation was made through XSEDE, the Extreme Science and Engineering Discovery Environment, a single virtual system funded by the National Science Foundation (NSF) that scientists use to interactively share computing resources,
000 cores of the Stampede supercomputer. Grabe was cautious about the potential application of this research,
uses high-throughput computer screening to calculate the properties not only of these three components but also their interactions with each other. f we can come up with an electrolyte that has a higher electrochemical window for multivalent batteries,
Using the supercomputers at Berkeley Lab National Energy Research Scientific Computing Center (NERSC), the researchers can screen hundreds of molecules per day.
and significantly increased survival in a mouse model of pancreatic neuroendocrine tumor. Bergers noted that the discovery potentially gives physicians a way to determine how effective anti-VEGF therapy might be in individual patients
says Chris Chang, an expert in catalysts for carbon-neutral energy conversions. n our system, nanowires harvest solar energy and deliver electrons to bacteria,
the researchers reproduced the hyperexcitability of epileptic neurons in mouse brains in vitro. They then injected GABA,
With a panel of 40 markers Montgomery and her colleagues have already been able to discern distinctions between NK cells derived from the two patient groups.
light photo-catalysts and ferroelectric materials in electronics. nalogous to the best metallic conductors such as copper or silver where the current is transported by electron, in d-Bismuth oxide
and others to feel the environments they inhabit through the likes of three-dimensional heads-ups displays. The prototype glove introduced at the George R. Brown School of engineering Design Showcase
so you can hook this up to a video game and when you reach out and grab a virtual object,
but they say programmers should find it fairly simple to implement the glove protocols into their games and other projects.
and might one day lead to microprocessors that are 100 times smaller than the ones in today computers.
The team used mouse models of asthma and human airway tissue from asthmatic and non-asthmatic people to reach their findings.
and that would be drilled core out. So NRL deconstructed the science. They started with purer chemicals. ousy chemicals in,
Many interesting and important structures in biological cells and computer chips have features smaller than that.
From several pictures under different illuminations, a single high-resolution image is constructed in the computer. So far, scientists have selected carefully the clearest glass optics for such imaging.
Multiple low resolution images of the object are combined then in the computer which leads to a clear image. he resolution improvement looks like the fog has clearedsays Hasan Yilmaz,
OS e
#Against the Stream Scientists have created microbe-sized beads that can utilize energy in the environment to self-propel upstream by purely physical means.
and the controller transmits it wirelessly to a smartphone or tablet, which then informs the diabetes patient that it is time to change foot position
or reconfigure the hardware to recover from a failure, on the fly. In March, the team tested the autonomous mission-planning system during a research cruise off the western coast of Australia.
but this is the first device that combines the imaging technology with hardware and software automation to create a complete diagnostic solution,
said Daniel Fletcher, an associate chair and professor of bioengineering, whose UC Berkeley lab pioneered the Cellscope. he video Cellscope provides accurate,
microcontrollers, gears, circuitry and a USB port. Control of the device is automated through an app the researchers developed for this purpose.
With a single touch of the screen by the healthcare worker, the phone communicates wirelessly via Bluetooth to controllers in the base to process
The worm count is displayed then on the screen. Fletcher said previous field tests revealed that automation helped reduce the rate of human error.
starting from the time the sample is inserted to the display of the results. Pricking a finger
paving the way for high-density storage to move from hard disks onto integrated circuits. This image taken from a computer simulation shows nanomagnets tilted at various angles,
with the white regions indicating greater angles of tilt. Researchers have found that even a small tilt of 2 degrees will facilitate magnetic switching.
in the Proceedings of the National Academy of Sciences, will lead to computers that turn on in an instant,
we want to be able to manufacture a computer chip that includes memory so that it is close to the computational action,
which is why magnets have not yet been integrated onto computer chips. Instead, there are separate systems for long-term magnetic memory.
These include a computer hard disk drive where data are stored and the various kinds of random-access memory,
or RAM, on the integrated circuits of the central processing unit, or CPU, where calculations and logic operations are performed.
A large portion of the energy used in computing is spent on transferring data from one type of memory to another.
However, the tool also runs on standard computer workstations commonly used by the electric industry.
and color of optical materials used in computer screens along with other consumer products. The work is centered on enhancing the arrangement of colloidsmall particles suspended within a fluid medium.
said Wyss Core Faculty member George Church, Ph d, . who is a pioneer in the converging fields of synthetic biology, metabolic engineering, and genetics.
a graduate researcher at the Wyss Institute who is pursuing his Ph d. in Engineering sciences from Harvard university. f we compared this to controlling a computer,
yet too small to trigger the thermonuclear reactions at their cores that power stars. The astronomers said their observations of LSR J1835+3259 indicate that the coolest stars
which causes the Earth auroral displays the planet magnetic field interacting with the solar wind. hat we see on this object appears to be the same phenomenon wee seen on Jupiter, for example,
The variation in this return signal over time is interpreted by a computer to which the reader is wired,
#Animal-eye view of the world revealed with new visual software New camera technology that reveals the world through the eyes of animals has been developed by University of Exeter researchers.
The software, which converts digital photos to animal vision, can be used to analyse colours and patterns and is particularly useful for the study of animal
The software has already been used by the Sensory Ecology group in a wide range of studies,
iewing the world through the eyes of another animal has now become much easier thanks to our new software. igital cameras are powerful tools for measuring colours
Our software allows us to calibrate images and convert them to animal vision, so that we can measure how the scene might look to humans
and nonhumans alike. e hope that other scientists will use this open access software to help with their digital image analysis. ntil now,
there has been no user friendly software programme that enables researchers to calibrate their images, incorporate multiple layers visible and UV channels-,convert to animal colour spaces,
This freely available open source software now offers a user friendly solution. Colour vision varies substantially across the animal kingdom,
one photograph taken through a visible-pass filter can be combined by the software with a second taken through an ultraviolet-pass filter.
The software can then generate functions to show the image through an animal eyes. The researchers have provided specific data on camera settings for commonly studied animals, such as humans, blue tits, peafowl, honey bees, ferrets and some fish.
reptiles and insects in their colourful sexual displays to attract mates. Source: University of Exete i
and using these to repair their damaged peripheral nerves but this approach has several disadvantages
Their collaborative research aims to break new ground in what computer scientist Jerry Zhu calls achine teachinga twist on the more familiar concept of machine learning. y hope is that machine teaching has an impact on the educational world.
which experts develop mathematical tools to help computers learn from data and detect patterns. The machine learner (the computer) is like a student The goal of machine learning is to develop models that will prove useful in the future
when dealing with large, often unwieldly data sets. Practical tasks like speech recognition are aided by machine learning. Machine teaching turns this concept on its ear.
The finding, in both mouse and human cells, suggests that manipulating a natural process could someday be an alternative way to not just reduce the severity of the flu,
In a series of experiments in mouse and human lung cells, Yount and colleagues showed that inhibiting NEDD4 from doing this job led to an accumulation of IFITM3 in the cells
rather than just relying on traditional chemical screens, says Hubbard, an assistant professor of pharmacology in the University of Alberta Faculty of medicine & Dentistry. ee moving towards a very logical type of treatment for genetic diseases,
Much like how a computer programmer edits computer code, scientists could one day replace a person broken
While most of the work described in the study was done in mouse models, the researchers also found similar cells in human livers.
Karin team examined three different mouse models of liver cancer. They found no signs of hybrid hepatocytes in any of the tumors,
The authors show that human irisin is similar to the mouse hormone and that it circulates in the range previously reported.
without relying on computer simulation or human intervention. Researchers led by the University of Cambridge have built a mother robot that can independently build its own children and test
Without any human intervention or computer simulation beyond the initial command to build a robot capable of movement,
Most work in this field is done using computer simulation. Although computer simulations allow researchers to test thousands or even millions of possible solutions,
this often results in a eality gapa mismatch between simulated and real-world behaviour. While using a computer simulation to study artificial evolution generates thousands,
or even millions, of possibilities in a short amount of time, the researchers found that having the robot generate its own possibilities,
without any computer simulation, resulted in more successful children. The disadvantage is that it takes time:
According to Iida, in future they might use a computer simulation to pre-select the most promising candidates,
Data from the scans were used to program a 3-D printer that laid down synthetic resins layer by layer.
and extrapolating from images on the computer to the patient, turning over a 3-D model in your hand is said transformative,
-D printing has become a regular part of our process, says Smith. t also a tool that allows us to educate our junior colleagues and trainees in a way that safe,
and tapping on our keyboards release energy that largely dissipates, unused. Several years ago, scientists figured out how to capture some of that energy
and expensive mouse avatars that are created by injecting human tumor cells into mice. his is really the first time that it been demonstrated that you can use a rapid methodology like this to spatially define cancer cells and macrophages,
What sets the team model apart from mouse avatars and hard plastic plates is that it can replicate much more accurately the sizes and shapes of the microenvironment within the patient problem area.
The technique uses a computer to acquire and process the neuronal response to the optical stimulus in real-time
Applications of these devices include advanced microscopes, displays, sensors, and cameras that can be mass-produced using the same techniques used to manufacture computer microchips. hese flat lenses will help us to make more compact and robust imaging assemblies,
said Mahmood Bagheri, a microdevices engineer at JPL and co-author of a new Nature Nanotechnology study describing the devices. urrently,
Manipulating the polarization of light is essential for the operation of advanced microscopes, cameras and displays;
#DNA-Guided 3-D Printing of Human Tissue Is unveiled A UCSF-led team has developed a technique to build tiny models of human tissues, called organoids,
#Mouth Guard Monitors Health Markers, Transmits Information Wirelessly to Smart Phone Engineers at the University of California,
San diego, have developed a mouth guard that can monitor health markers, such as lactate, cortisol and uric acid,
in saliva and transmit the information wirelessly to a smart phone, laptop or tablet. The technology,
researchers showed that the mouth guard sensor could offer an easy and reliable way to monitor uric acid levels.
In the past, the patient would have needed blood draws to monitor levels and relied instead on symptoms to start
Fabrication and design Wang team created a screen-printed sensor using silver, Prussian blue ink and uricase,
and then wirelessly transmits data to a smart phone, tablet or laptop. The entire electronic board occupies an area slightly larger than a U s. penny.
including temporary tattoos that monitor glucose, ultra-miniaturized energy-processing chips and pens filled with high-tech inks for Do it yourself chemical sensors.
At its core, however, is a rule known as Heisenberg uncertainty principle. This states that in any situation in which a particle has linked two properties,
Hayes said. nd it turns out that we have a core mechanism that could be integrated with smartphones
Revealed by a brand new lectron camera, one of the world speediest, this unprecedented level of detail could guide researchers in the development of efficient solar cells, fast and flexible electronics and high-performance chemical catalysts.
Understanding these dynamic ripples could provide crucial clues for the development of next-generation solar cells, electronics and catalysts.
Thin films of Mos2 are also under study as possible catalysts that facilitate chemical reactions. In addition
Computers are used often as a metaphor for the brain with logic boards and microprocessors representing neural circuits and neurons, respectively.
and in a way not achieved by computers. Researchers from the MRC CDN, led by Professor Oscar Marín,
Now, a team led by Wyss Institute Core Faculty member David Mooney, Ph d.,has developed a new strategy embedding stem cells into porous,
from a genetic mouse model of Alzheimer disease. Then scientists put new technology to its practical application.
The computational elements in Safepay consist of a mobile device and a server which distributes disposable credit card numbers.
The physical entity is the magnetic credit card chip controlled by a mobile application inside a customer mobile device.
The paper outlines the overall architecture and server-side deployment model the design of Safepay, prototype implementation and security analysis. Here how it works:
which communicates with the bank server. During transactions, the mobile application acquires disposable credit card numbers from the bank server,
generates a wave file, plays the file to generate electrical current, and then drives the magnetic card chip via an audio jack or Bluetooth.
and visualization software and used it on a laptop computer to leverage an emerging DNA-sequencing technology known as nanopore sequencing. his point-of-care genomic technology will be particularly attractive in the developing world,
and computational server capacity, are limited often severely, said Chiu. Nanopore technology, currently under development by many private enterprises, distinguishes individual nucleic acids by the distinctive perturbations they create in electric currents as they pass through microscopic pores.
The USB-powered sequencer used by Chiu research team, dubbed Minion, was made by Oxford Nanopore technologies
and creating nanoscale spheres made up of platelet membranes with Dox-gel cores. These spheres are treated then
#Raising Computers to Be Good Scientists Making sense of the new scientific data published every year including well over a million cancer-related journal articles is a tall order for the contemporary scientist.
Reading and Assembling Contextual and Holistic Mechanisms From Textwill create a computer system that reads papers, extracts information on biochemical pathways,
REACH researchers are laying the foundation for interactive software that would allow drug developers, or maybe even doctors, to provide lots of information,
In turn, it could model how a specific treatment would interact with the patient. heyl be the Microsofts and Googles of biomedicine,
trained a computer system to read papers using hundreds of algorithms. One, for example, allows it to understand that ouse,
think that collaborative computers are going to be like children, and wel have to raise them, in a way.
by teaching it to differentiate between species (a yeast cell is different from a mouse).
much as a scientist or a doctor might. would like to see this usher in computers understanding complex things at a level that we just can,
#Ground-breaking computer program diagnoses cancer in two days In the vast majority of cancer cases, the doctor can quickly identify the source of the disease, for example cancer of the liver, lungs, etc.
and created a new diagnostic technology based on advanced self learning computer algorithms whichn the basis of a biopsy from a metastasisan with 85 per cent certainty identify the source of the disease
The pattern of mutations is analysed in a computer program which has been trained to find possible primary tumour localizations.
#Scientists test new gene therapy for vision loss from a mitochondrial disease NIH-funded study shows success in targeting MITOCHONDRIAL DNA in mice Researchers funded by the National institutes of health have developed a novel mouse model for the vision disorder
Their success in creating a mouse model of LHON and using it to test an investigational gene therapy is described today in the Proceedings of the National Academy of Sciences.
This modified virus has been the key to creating a mouse that replicates LHON and to an investigational gene therapy for LHON that is currently in clinical trials.
To create a mouse model for LHON, the researchers loaded the virus with a defective copy of the ND4 gene carrying the same mutation that causes about 70 percent of LHON cases.
Then they injected the virus into fertilized mouse egg cells, and grew the cells to maturity.
the researchers had their mouse model. The presence of the virally encoded ND4 mutation in the eye was confirmed by essentially doing an eye exam to look for the red fluorescent marker.
Prior to development of the new mouse model Dr. Guy lab had shown that they could produce temporary signs of LHON in mice.
The mouse research is helping inform an ongoing NEI-supported clinical trial, which is led by Dr. Guy
#Scientists grow organic semiconductor crystals vertically for first time Our smartphones, tablets, computers and biosensors all have improved because of the rapidly increasing efficiency of semiconductors.
Since the turn of the 21st century, organic, or carbon-based, semiconductors have emerged as a major area of interest for scientists
flat panels that can only absorb light from one surface. The study, led by Richard Kaner,
says Conor Walsh, Ph d.,Wyss Institute Core Faculty member, Assistant professor of Mechanical and Biomedical engineering AT SEAS, founder of the Harvard Biodesign Lab AT SEAS,
and product development through the partnership with Trajan. he hemapen is an example of ASTECH core foundations;
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