Synopsis: Nanotechnology: Nanoparticles:

and circulating tumor cells than using the drugs in a nanogel delivery system without the platelet membrane. e like to do additional preclinical testing on this technique,

which incorporates nanoparticles into polymers through a technique called electrospinning, was developed by a team from the University of North Texas System College of Pharmacy,

When these nanoparticles are used as the anode in a lithium ion battery, the researchers found it had a storage capacity of 1. 2 ampere-hours per gram.

At one end of that plane there is a so-called quantum dot: a tiny trap for electrons, only a hundred nanometers wide, in which owing to quantum mechanics the electrons exist in well-defined energy states similar to those of an atom.

Such quantum dots are, therefore, also known as"artificial atoms"."At the other end, just a few micrometers away, a bent electrode acts as a curved mirror that reflects electrons

In their experiments, the physicists detect this wave nature by measuring the current flowing from the quantum dot to the curved mirror.

and thus couple coherently to the quantum dot",stresses Rössler, who developed the experiment in the group of ETH professor Klaus Ensslin.

Indeed, the researchers were able to show that the interaction between the electrons in the quantum dot

"In the future, this spin-coherent coupling could make it possible to connect quantum dots over large distances, "says Zilberberg,

Suitable for quantum computersfor some time now, quantum dots have been considered as possible candidates for making so-called quantum bits or"qubits,

Until now the quantum dots in such a computer needed to be very close to each other in order to achieve the necessary coupling for performing calculations.

With the help of a resonator and a quantum dot simulating such an impurity, the physicists hope to be able to study the Kondo effect very precisely.

Efstathios Karathanasis, a biomedical engineer at Case School of engineering, has developed chainlike nanoparticles that can carry drugs across the blood-brain barrier that keeps standard medicines from reaching their target--a highly aggressive brain cancer called

Karathanasis'lab developed a short chain of magnetic nanoparticles made of iron oxide and modified the surfaces so one links to the next, much like Lego building blocks.

semiconducting and insulating nanoparticles. Currently, printed conductive patterns use a combination of poorly conducting carbon with other materials, most commonly silver

"What's unique about this paper is that we show not the use of metal particles, not the use of metal nanoparticles,

"There are so many atoms inside the nanoparticle that never do anything. But in our process the atoms driving catalysis have no metal atoms next to them.

such as platinum-copper single atom alloy nanoparticles supported on an alumina substrate, and then tested them under industrial pressure and temperatures."

Previously, nanoparticle walkers were only able to walk on precise and programmed one-and two-dimensional paths.

#Accidental nanoparticles could let lithium ion batteries live another day A new study from MIT could keep lithium ion battery technology on the track for another few laps,

The breakthrough comes from an accidentally created synthetic metal nanoparticle that could solve some of the oldest problems for batteries.

Their testing shows that the nanoparticles could allow up to four times the charge retention after a long lifetime of use,

Researchers from MIT were attempting to address this problem with different treatments for aluminum nanoparticles

and that work led them to bathe nanoparticles in a mixture of sulfuric acid and titanium oxysulfate,

This resulted in an unforeseen egg-like nanoparticle design, in which a olkof aluminum is covered in a hellof titanium dioxide.

#New quantum dot could make quantum communications possible A new form of quantum dot has been developed by an international team of researchers that can produce identical photons at will,

With these quantum dots at their disposal, engineers might be able to start thinking about new, large-scale quantum communications networks.

So, unless youe less than one quantum dot range away from the person you want to talk to,

These quantum dots basically achieve perfect single-photon emission by super-cooling the quantum dots so the emitting atoms do not fluctuate.

or perhaps even find a way to surveil these quantum dots themselves, reading each photon as it absorbed and reemitted.

The special feature of the alloy is that these individual crystals are tinyhis is referred to as a nanocrystalline material. lthough nanocrystalline materials have many desirable properties,

which involved loading the drug into nanoparticles to improve the speed at which is destroys clots.

#Aluminum"yolk"nanoparticles deliver high-capacity battery recipe Researchers at MIT and Tsinghua University in China have found a way to more than triple the capacity of the anodes,

-and-shell"nanoparticles, is reportedly simple to manufacture and is especially promising for high-power applications.

They have done so by creating nanoparticles with a solid titanium outer shell and an inner aluminum"yolk"that can freely expand

a process that coated the nanoparticles in a hard shell three to four nanometers thick.

This gave the aluminum nanoparticles enough room to collect lithium ions and expand considerably as needed, without damaging the electric contacts of the cell.

Each of its pages is made from a thick sheet of paper impregnated with silver and copper nanoparticles,

"The biodegradable polymer is reinforced with montmorillonite clay nanoparticles (we've seen nanoparticles used in other ways to heal bones) for strength,

or copper nanoparticles that kill bacteria found in contaminated water. Each page could filter 99%of bacteria

#Immune cell binding nanoparticle could lead to new sepsis treatment A nanoparticle that binds to immune cells in the body has been shown to tune down inflammation and offer a potential first-of-a-kind treatment for sepsis.

Researchers sprinkled a plastic nanoparticle with sialic acid ligands that modulated macrophage immune cells. This produced a therapeutic response in mouse models of sepsis, in human lung cells and an ex vivo human lung model.

or seen an effect within hours. rotein targetingthe nanoparticles target Siglecs, proteins found on the surface of immune cells that recognise a type of sugar called sialic acid. hese receptors help the immune system distinguish between self and non-self

molecular biologist James Paulson at the Scripps Research Institute in the US told this publication. he authors exploit Siglec function by attaching sialic acids to nanoparticles that exploit the function of Siglecs and control inflammation,

but do conjugated so only when to a nanoparticle. acrophages try to gobble up the nanoparticles and remove them from circulation,

so we are getting a targeting effect using the nanoparticle that you couldn get with a soluble antibody,

These findings are surprising ince it had not been reported previously that engaging this siglec receptor with nanoparticles displaying the glycan (sugar) ligand would have such profound effects on inflammation,

LEDS can be produced by quantum dots, or tiny crystals that have luminescent properties. Quantum dots (QDS) can be made with numerous materials, some

of which are rare and expensive to synthesize, and even potentially harmful to dispose of. Some research over the past 10 years has focused on using carbon dots (CDS),

Compared to other types of quantum dots CDS have lower toxicity and better biocompatibility, meaning they can be used in a broader variety of applications.

Another researcher in Saldaña lab is looking at adding nanoparticles on the films. Right now

but with nanoparticles, more could be added and released strategically. Meanwhile, Saldaña says, the overall goal is to achieve complete use of the available biomass.

#Nanoparticles Penetrate Mucus Barrier to Bring Gene therapy to Lung Parenchyma A collaboration between researchers at Johns hopkins university

and Federal University of Rio de janeiro in Brazil has managed to develop nanoparticles capable of carrying DNA molecules through the previously impenetrable mucus barrier of the lungs.

The nanoparticles are biodegradable and don present problems associated with DNA ferrying viruses. Previously developed nanoparticles suffered from a poor ability to pass through mucus due to their charge

and also bunched in groups, further limiting their usefulness. The nanoparticles are made of biodegradable polymers called poly (ß-amino esters)( PBAES)

and in lab tests were able to pass through mucus taken from real patients. To test whether genes delivered this way would actually work inside a real body,

the researchers loaded DNA strings coding for light producing proteins into the nanoparticles and had animals inhale them into their lungs.

the Drinkable Book features pages embedded with silver or copper nanoparticles. In 25 trials at contaminated drinking sites in Ghana and Bangladesh, the paper was effective at removing 99 percent of bacteria."

and drug loaded nanoparticles to unload medication when the skin flexes and contracts. The idea is that this kind of approach can deliver drugs transdermally only when needed.

each filled with drug loaded nanoparticles. The nanoparticles are designed to slowly release a medication into the capsules where they reside.

The capsules themselves are not impermeable, but will let compounds through when enough pressure is applied to them.

The combination of the mechanisms lets the nanoparticles load the capsules with a small amount of a medication and release it into the skin immediately on demand d

potentially offering an easy way to monitor the assembly of nanoparticles, or to study how mass is distributed within a cell.

New research by the Nanoparticles By design Unit at the Okinawa Institute of Science and Technology Graduate University (OIST), in collaboration with the Materials Center Leoben Austria and the Austrian Centre for Electron microscopy and Nanoanalysis has developed an efficient

The researchers used a copper oxide nanowire decorated with palladium nanoparticles to detect carbon monoxide a common industrial pollutant.

They found that copper oxide nanowires decorated with palladium nanoparticles show a significantly greater increase in electrical resistance in the presence of carbon monoxide than the same type of nanowires without the nanoparticles.

The OIST Nanoparticles By design Unit used a sophisticated technique that allowed them to first sift nanoparticles according to size,

then deliver and deposit the palladium nanoparticles onto the surface of the nanowires in an evenly distributed manner.

This even dispersion of size selected nanoparticles and the resulting nanoparticles-nanowire interactions are crucial to get an enhanced electrical response.

The OIST nanoparticle deposition system can be tailored to deposit multiple types of nanoparticles at the same time, segregated on distinct areas of the wafer where the nanowire sits.

with each device utilizing a different type of nanoparticle. Compared to other options being explored in gas sensing

However, different nanowire-nanoparticle material configurations are currently being investigated in order to lower the operating temperature of this system."

"I think nanoparticle-decorated nanowires have a huge potential for practical applications as it is possible to incorporate this type of technology into industrial devices,

Mukhles Sowwan at the OIST Nanoparticles By design Unit. Image: Palladium nanoparticles were deposited on the entire wafer in an evenly distributed fashion,

as seen in the background. They also attached on the surface of the copper oxide wire in the same evenly distributed manner,

On the upper right is a top view of a single palladium nanoparticle photographed with a transmission electron microscope (TEM)

The nanoparticle is made up of columns consisting of palladium atoms stacked on top of each other. This image has been modified from the original to provide a better visualization.

New research by the Nanoparticles By design Unit at the Okinawa Institute of Science and Technology Graduate University (OIST), in collaboration with the Materials Center Leoben Austria and the Austrian Centre for Electron microscopy and Nanoanalysis has developed an efficient

The researchers used a copper oxide nanowire decorated with palladium nanoparticles to detect carbon monoxide a common industrial pollutant.

They found that copper oxide nanowires decorated with palladium nanoparticles show a significantly greater increase in electrical resistance in the presence of carbon monoxide than the same type of nanowires without the nanoparticles.

The OIST Nanoparticles By design Unit used a sophisticated technique that allowed them to first sift nanoparticles according to size,

then deliver and deposit the palladium nanoparticles onto the surface of the nanowires in an evenly distributed manner.

This even dispersion of size selected nanoparticles and the resulting nanoparticles-nanowire interactions are crucial to get an enhanced electrical response.

The OIST nanoparticle deposition system can be tailored to deposit multiple types of nanoparticles at the same time, segregated on distinct areas of the wafer where the nanowire sits.

with each device utilizing a different type of nanoparticle. Compared to other options being explored in gas sensing

However, different nanowire-nanoparticle material configurations are currently being investigated in order to lower the operating temperature of this system."

"I think nanoparticle-decorated nanowires have a huge potential for practical applications as it is possible to incorporate this type of technology into industrial devices,

Mukhles Sowwan at the OIST Nanoparticles By design Unit n

#Flicking the switch on spin-driven devices Compressing magnetically and electrically active crystals in one direction unlocks exotic spintronic switching activityby breaking the symmetry of ultiferroiccrystals using a special compression cell,

creating an electrode made of nanoparticles with a solid shell, and a olkinside that can change size again and again without affecting the shell.

The use of nanoparticles with an aluminum yolk and a titanium dioxide shell has proven to be he high-rate champion among high-capacity anodes

That where the idea of using confined aluminum in the form of a yolk-shell nanoparticle came in.

#New protein nanoparticles allow scientists to track cells and interactions within them Engineers have designed magnetic protein nanoparticles that can be used to track cells

or to monitor interactions within cells. The particles, described today in Nature Communications, are enhanced an version of a naturally occurring, weakly magnetic protein called ferritin. erritin,

which is as close as biology has given us to a naturally magnetic protein nanoparticle, is really not that magnetic.

The new ypermagneticprotein nanoparticles can be produced within cells allowing the cells to be imaged or sorted using magnetic techniques.

prompting them to start producing the protein on their own. ather than actually making a nanoparticle in the lab

resulting in micrometer-per-second nanoparticle transport by harnessing a single plasmonic nanoantenna, which until now has been thought to be said impossible

and contains a small amount of platinum in the form of nanoparticles. This new composite presents some special talents.

The produced aerosol is directed over the heated substrate using a stream of nitrogen gas resulting into a polycrystalline thin film grown on the chalcopyrite substrate over time with embedded nanoparticles of platinum.

thanks to diamond nanocrystals used as temperature sensors Abstract: Precise targeting biological molecules, such as cancer cells,

Using a chemical method to attach gold nanorods to the surface of a diamond nanocrystal, the authors have invented a new biocompatible nanodevice.

while accurately sensing temperature with the nanocrystals. The authors'lab specialises in fabricating bright fluorescent diamond nanocrystals.

The paticularity of these nanocrystals is that they contain a high concentration of punctual colour centre defects.

When exposed to green light, these centres emit a red fluorescent light, useful for sub-cellular imaging applications.

By introducing gold nanoparticles to the nanocrystal, the authors make it possible to convert the incoming laser light into extremely localised heat.

These gold nanoparticles can therefore act as switchable nanoheaters for therapies based on delivering intense and precise heat to cancerous cells,

The novelty of this study is that it shows that it is possible to use diamond nanocrystals as hypersensitive temperature sensors with a high spatial resolution-ranging from 10 to 100 nanometers-to monitor the amount of heat delivered to cancer cells s

#Sandcastles inspire new nanoparticle binding technique"Nanocapillary-mediated magnetic assembly of nanoparticles into ultraflexible filaments and reconfigurable networks"Abstract:

Here, we show that capillarity-mediated binding between magnetic nanoparticles coated with a liquid lipid shell can be used for the assembly of ultraflexible microfilaments and network structures.

These filaments can be regenerated magnetically on mechanical damage, owing to the fluidity of the capillary bridges between nanoparticles and their reversible binding on contact.

Sandcastles inspire new nanoparticle binding technique If you want to form very flexible chains of nanoparticles in liquid

in order to build tiny robots with flexible joints or make magnetically self-healing gels, you need to revert to childhood

researchers from North carolina State university and the University of North carolina-Chapel hill show that magnetic nanoparticles encased in oily liquid shells can bind together in water,

"We then add a magnetic field to arrange the nanoparticle chains and provide directionality, "said Bhuvnesh Bharti,

and makes the bridges fragile, leading to breaking and fragmentation of the nanoparticle chains. Yet the broken nanoparticles chains will reform

if the temperature is raised, the oil liquefies and an external magnetic field is applied to the particles."

Researchers will be able to study samples ranging from engineered nanoparticles and nanostructures to naturally occurring biological polymers, tissues and plant cells.

#Targeted drug delivery with these nanoparticles can make medicines more effective: Nanoparticles wrapped inside human platelet membranes serve as new vehicles for targeted drug delivery The research,

led by nanoengineers at the UC San diego Jacobs School of engineering, was published online Sept. 16 in Nature.""This work addresses a major challenge in the field of nanomedicine:

targeted drug delivery with nanoparticles, "said Liangfang Zhang, a nanoengineering professor at UC San diego and the senior author of the study."

platelet-mimicking nanoparticles can directly provide a much higher dose of medication specifically to diseased areas without saturating the entire body with drugs."

The ins and outs of the platelet copycats On the outside, platelet-mimicking nanoparticles are cloaked with human platelet membranes,

which enable the nanoparticles to circulate throughout the bloodstream without being attacked by the immune system. The platelet membrane coating has another beneficial feature:

and certain pathogens such as MRSA bacteria, allowing the nanoparticles to deliver and release their drug payloads specifically to these sites in the body.

Enclosed within the platelet membranes are made nanoparticle cores of a biodegradable polymer that can be metabolized safely by the body.

The nanoparticles can be packed with many small drug molecules that diffuse out of the polymer core and through the platelet membrane onto their targets.

To make the platelet-membrane-coated nanoparticles, engineers first separated platelets from whole blood samples using a centrifuge.

the platelet membranes were broken up into much smaller pieces and fused to the surface of nanoparticle cores.

The resulting platelet-membrane-coated nanoparticles are approximately 100 nanometers in diameter, which is one thousand times thinner than an average sheet of paper.

This cloaking technology is based on the strategy that Zhang's research group had developed to cloak nanoparticles in red blood cell membranes.

The researchers previously demonstrated that nanoparticles disguised as red blood cells are capable of removing dangerous pore-forming toxins produced by MRSA, poisonous snake bites and bee stings from the bloodstream.

Platelet copycats at work In one part of this study, researchers packed platelet-mimicking nanoparticles with docetaxel,

Researchers observed that the docetaxel-containing nanoparticles selectively collected onto the damaged sites of arteries

platelet-mimicking nanoparticles can also greatly minimize bacterial infections that have entered the bloodstream and spread to various organs in the body.

Researchers injected nanoparticles containing just one-sixth the clinical dose of the antibiotic vancomycin into one of group of mice systemically infected with MRSA bacteria.

"Our platelet-mimicking nanoparticles can increase the therapeutic efficacy of antibiotics because they can focus treatment on the bacteria locally without spreading drugs to healthy tissues

"We hope to develop platelet-mimicking nanoparticles into new treatments for systemic bacterial infections and cardiovascular disease."

The nanosensor consists of plasmonic nanoparticles that are placed at regular distance from each other. Based on the results of the modeling

The role of nanosensor between body surface and the detector is to strengthen the signal and taking samples through plasmonic effects of nanoparticles.

A nanocomposite coating has been produced in this research by combining hydroxyapatite nanoparticles as the base material and diopside ceramic.

#Brightness-equalized quantum dots improve biological imaging"In this work, we have made two major advances--the ability to precisely control the brightness of light-emitting particles called quantum dots,

and the ability to make multiple colors equal in brightness, "explained Andrew M. Smith, an assistant professor of bioengineering at Illinois."Previously light emission had an unknown correspondence with molecule number.

"Brightness-Equalized Quantum dots,"published this week in Nature Communications. According to the researchers, these new materials will be especially important for imaging in complex tissues

and Zhitomirsky, a materials science and engineering professor, demonstrates an improved three-dimensional energy storage device constructed by trapping functional nanoparticles within the walls of a nanocellulose foam.

The type of nanocellulose used is called cellulose nanocrystals and looks like uncooked long-grain rice but with nanometer-dimensions.

such as platinum-copper single atom alloy nanoparticles supported on an alumina substrate, and then tested them under industrial pressure and temperatures."

In addition, the product is able to form hydroxyapatite nanoparticles to create chemical bonds with bone tissue in the body.

#What are these nanostars in 2-D superconductor supposed to mean? Physicists from France and Russia have discovered magnetic disturbances in 2d superconductor layer,

the observed effect looks like magnetic"nanostars in the superconducting univers";"building constellations of them can be used in quantum electronics.

Physicists from France and Russia have discovered that the magnetic atoms in a two-dimensional layered superconductor create electronic disturbances that look like oscillating"nanostars".

Titanium dioxide nanoparticles doped with elements such as strontium and chrome were used in the production of the coating.

The coating of nanoparticles contains titanium dioxide and other spherical nanoparticles in average size of 60 nm.

plasmonic nanoparticles--are characterized by low efficiency and significant losses. Therefore, coming up with a compact photonic switch was a very challenging task.

they found out that silicon nanoparticles are exhibit strong resonances in the visible spectrum-the so-called magnetic dipole resonances.

This type of resonance is characterized by strong localization of light waves on subwavelength scales, inside the nanoparticles.

Nanoparticles were fabricated in the Australian National University by e-beam lithography followed by plasma-phase etching.

In the nearest future, we are going to test such nanoparticles in integrated circuits

#Magnetic Nanosorbents Eliminate Fluoride from Water Researchers from Tehran University of Medical sciences used low-cost and available raw materials for the laboratorial production of nanosorbents with high efficiency in elimination of fluoride from contaminated water.

magnetic properties have been created in the structure of the sorbent by using iron oxide nanoparticles. The synthesized magnetic composite is separated from the solution phase in the presence of a magnetic field in a short time through this method.

The spherical arrangement of approximately 100 DNA strands attached to a benign nanoparticle core made of lipid

The single stranded-dna DNA on the nanoparticle core can be positioned ideally and oriented to specifically and fully interact with the targeted toll-like receptors.

The study is published today in the journal Physical Review Letters("Cavity cooling a single charged nanoparticle".

Observing quantum effects in large and heavy objects like these nanoparticles would also shed light on the role of gravity in quantum physics s

The ultrathin nanoparticles are embedded in a collagen-based hydrogel a biodegradable gel used in several biomedical applications because of its compatibility with the body.

As part of future research, Gaharwar plans further investigation into the process by which the nanoplatelets trigger cell differentiation.

would allow the injury site to receive blood flow as part of the enhanced healing process initiated by the nanoparticles.

#Medical nanoparticles for the local treatment of lung cancer Nanoparticles can function as carriers for medicines to combat lung cancer:

In the journal, ACS Nano("Protease-Mediated Release of Chemotherapeutics from Mesoporous Silica Nanoparticles to ex Vivo Human and Mouse Lung Tumors"),the scientists reported that this approach led to a significant increase

Sabine van Rijt, CPC/ilbd, Helmholtz Zentrum Mnchen) Nanoparticles are extremely small particles that can be modified for a variety of uses in the medical field.

For example, nanoparticles can be engineered to be able to transport medicines specifically to the disease site while not interfering with healthy body parts.

were able to show nanoparticles'selective drug release to human lung tumour tissue for the first time. Tumour specific proteins were used to release drugs from the nanocarriers Tumour tissue in the lung contains high concentrations of certain proteases,

As it shrinks, the quantum dots come closer together, increasing their conductivity, as measured by the electrodes."

#New study shows bacteria can use magnetic nanoparticles to create a'natural battery'(Nanowerk News) New research shows bacteria can use tiny magnetic particles to effectively create a'natural battery.'

#Novel nanoparticle therapy promotes wound healing (w/video)( Nanowerk News) An experimental therapy developed by researchers at Albert Einstein College of Medicine of Yeshiva University cut in half the time it takes to heal

"e envision that our nanoparticle therapy could be used to speed the healing of all sorts of wounds,

and then put the drug in tiny gel capsules called nanoparticles and applied the nanoparticles to wounds on mice.

The treated wounds healed much faster than untreated wounds. FL2 belongs to the fidgetin family of enzymes,

and study co-leader Adam Friedman, M d.,director of dermatologic research at Einstein and Montefiore, who together had developed nanoparticles that protect molecules such as sirna from being degraded as they ferry the molecules to their intended targets.

The nanoparticles with their sirna cargoes were tested then by topically applying them to mice with either skin excisions or burns.

#Next important step toward quantum computer with quantum dots Physicists at the Universities of Bonn and Cambridge have succeeded in linking two completely different quantum systems to one another.

The results have now been published in Physical Review Letters("Direct Photonic Coupling of a Semiconductor Quantum dot and a Trapped Ion".

There the so-called quantum dots (abbreviated: qdots) play the role of the forgetful genius. Quantum dots are unbeatably fast,

when it comes to disseminating quantum information. Unfortunately, they forget the result of the calculation

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