what works with food also works with other things, like creating new pharmaceuticals and cancer-fighting proteins.
#Tadpole-like endoscope swims through gastrointestinal tract in search of cancer Endoscopes are essential tools for the medical examination of many organs of the human body,
With cancers of the gastrointestinal (GI TRACT such as esophageal cancer, stomach cancer, and colon cancer, being some of the most commmon of all cancers in the world,
a range of procedures are necessary to physically examine all parts of the GI for maximum diagnostic effect.
Of these, gastroscopy is used to help diagnose esophageal and stomach cancer, whilst intestinal and coleorectal cancers can be determined with the use of capsule endoscopy and colonoscopy, respectively.
Unfortunately, all of these procedures are costly to perform and can place a great deal of stress on someone who may already be quite ill.
The new Tadpole Endoscope (TE on the other hand, is a relatively noninvasive device that is simply swallowed like a large pill
including following tumor removal, spinal fusion surgery or fractures. Normally, bone grafts involve using bone from another part of the patient's body,
#5-yr Study Reveals Why Ovarian Cancer Recurs and How to Stop It Scientists have discovered finally why ovarian cancer frequently comes back after patients receive chemotherapynd theye also found a way to potentially eliminate the recurrence rate for half of patients who have the disease.
A five-year study at the University of California at Los angeles found that coupling chemotherapy with an experimental drug called Birinapant greatly improved survivability in laboratory tissue.
At the core of the problem is the way doctors test for ovarian cancer. One of the things they look for is called a protein CA125.
Chemotherapy targets cells containing the protein and that knocks out the cancer. The UCLA researchers found other cells
allowing ovarian cancer to recur in more than 80%of people treated with chemotherapy alone. e found that these cells were like little time bombs,
and then later initiating tumor growth, Dr. Sanaz Memarzadeh, a senior author of the study said.
the combined treatment attacks the cancer on both fronts. Ebola Suit-Liberia-USAID-CC-Morganawingard-adjusted The researchers plan clinical trials on actual patients next.
Not everyone with ovarian cancer would benefit from this particular combination of therapies. The good news is these two types of cells are present in about 50%of ovarian cancer patients who would be candidates for this dual treatment.
Researchers are looking at other biomarkers to see if theye been missing still other hidden cancer ime bombs. og-nose-cancer-Photo-credit-Itsgreg-CC-750px The study was funded by grants from 10 foundations
and government agencies and was published on August 3 in the journal Nature h
#Teenage Girl Turns Plastic Trash Into Million-Dollar Biofuel An Egyptian teenager has discovered an inexpensive way to turn plastic trash into fuel
How We Might Starve Tumors by Cutting off Food supply In their hunger to find ways to cure cancer,
scientists may have found a method to starve tumors to death. Cancer cells must find nutrients to grow.
and their research suggests it may be possible to starve tumors by targeting it. e found that aggressive cancer cells manufacture more PAT4,
They found that cancers with low PAT4 levels grew more slowly while patients that showed higher levels had more trouble fighting tumors and a higher chance of remission.
They also discovered that if doctors can reduce the PAT4 levels, it will slow tumor growth.
Now that theye identified a mechanism that allows tumors to grow the researchers believe they can find a way to use it as part of a combination treatment that will lead to a higher survival rate for patients.
They believe it can be incorporated into other, traditional cancer treatments to fight the disease more effectively.
The research, published today in the science journal Oncogene, was funded by Cancer Research UK, the Wellcome Trust and the Biotechnology and Biological sciences Research Council h
#Solar Tracking: A Key Technology for Unlocking the Full Potential of Utility-Scale PV Quotes for large solar photovoltaic projects in sunny parts of the United states are coming in at an astounding 4. 5 to 5. 5
According to the researchers, thousands of men and even young boys rendered infertile by cancer and other diseases could benefit. his breakthrough opens the way for therapeutic avenues that have been awaited eagerly by clinicians for many years,
Yet more than 15,000 young cancer patients are affected throughout the world. Nor is there any solution for the 120,000 adult men who suffer from infertility that cannot be treated using existing technologies.
The number of years lived with disability have increased in almost every country, attributable to the growth of chronic diseases such as cardiovascular and respiratory diseases, cancer, back pain, mental health disorders, dementia, road injuries, HIV
romidepsin-a drug currently being used to treat cancer-to be the most potent, and thus successful, inhibitor trialled so far.
#Patients Will printed Swallow 3d Tadpole Endoscope That Provides Diagnosis of Cancers A team from the Institute of Precision Engineering at the Chinese University of Hong kong has developed 3d-printed tadpole-like devices that can
improve diagnosis of various cancers by entering the patient stomach and wirelessly transmitting images of
and relatively noninvasive solution that could improve cancer diagnosis. Developed to be swallowed just like a large pill (it is a bit bigger than a small coin),
and Genistein, the compound found in soybean which has been suggested to play a role in prevention of steroid-hormone related cancers, particularly breast cancer.
and Genistein, the compound found in soybean which has been suggested to play a role in prevention of steroid-hormone related cancers, particularly breast cancer.
Those with mutations in polycystic kidney disease genes formed balloon-like, fluid-filled sacks, called cysts, from kidney tubules.
#Cancer Tech: New Devices Could Speed up Treatment Treating cancer is sometimes a process of trial and error,
because any given drug or drug combination does not work the same for all patients.
while doctors seek the right chemicals to beat back a tumor. Now, two research teams say they have found ways to speed up the process by allowing doctors to try multiple treatments at once:
In Seattle, researchers at the Fred Hutchinson Cancer Research center and the company Presage Biosciences designed a device called CIVO that includes up to eight needles arranged in an array.
The device can be used to inject multiple drugs into tumors that are close to the surface of a person's skin.
First, the needles are loaded with drugs, pressed into the tumor and then withdrawn, with each needle leaving behind a columnlike trail of a drug that spans the full depth of the tumor.
one to three days later, researchers can remove a piece of the tumor and examine the cells to see the effect of each drug
whether it killed the tumor cells, slowed their growth or had no effect. That analysis can tell doctors
if the cancer is resistant"to the drug that's being prescribed, said Dr. James Olson,
Top 10 Cancer-Fighting Foods With CIVO, doctors"can compare drug A to drug B,
which are cancers of the lymph system, and had enlarged lymph nodes. The patients said they had very little pain with the injections, according to the report.
the cylinder is designed to be implanted into the tumor, and then diffusion allows the drugs to move from the tubes into the surrounding cancerous tissue.
A biopsy of the tumor is taken a day or two later a doctor removes the cylinder
and a small amount of the cancer tissue around it. As with CIVO, the aim is to let doctors look at the cancerous tissue,
But the implant offers a way to attack cancers that are deeper in the body and thus less accessible to injections.
and the patient would avoid enduring the side effects of drugs that wouldn't end up treating the cancer."
and the MIT researchers'work was funded by the National Cancer Institute and Massachusetts-based biotech company Kibur Medical.
the late American film critic who lost his jawbone to cancer, is autograft. This is basically a euphemism for cutting a piece of bone out of one part of the body
But a chance meeting between Petri and a bladder cancer expert, Dr. Dan Theodorescu, who is director of the University of Colorado Cancer Center,
or more effective in killing the cancer. Petri merely substituted E. histolytica for a drug.
or water contaminated with its cysts. The ameba passes into the environment via feces and can survive outside the human body for several weeks in this protective cyst form.
E. histolytica infection is endemic in regions with poor sanitation and improving sanitation has been the primary means to stop infections,
"What's an ameba have to do with cancer, after all?""Theodorescu said. But recently the two were working together, on a hiring committee,
But a chance meeting between Petri and a bladder cancer expert, Dr. Dan Theodorescu, who is director of the University of Colorado Cancer Center,
or more effective in killing the cancer. The 10 Most Diabolical and Disgusting Parasites Petri merely substituted E. histolytica for a drug.
or water contaminated with its cysts. The ameba passes into the environment via feces and can survive outside the human body for several weeks in this protective cyst form.
E. histolytica infection is endemic in regions with poor sanitation and improving sanitation has been the primary means to stop infections,
"What's an ameba have to do with cancer, after all?""Theodorescu said. Tiny & Nasty: Images of Things That Make Us Sick
#New Blood test Predicts Breast cancer Relapse Months In advance (VIDEO) Researchers from The Institute of Cancer Research in London have developed a new blood test,
The technology, published in journal Science Translational Medicine, measures the level of circulating tumor DNA (ctdna),
the DNA that has been shed by circulating tumor cells, in plasma isolated from blood. By measuring the level of genetic mutations in the ctdna,
and successfully did a small cancer gene study using this technique. The group was able to add a few modified cells with the Rasg12v cancer gene in a printed organoid array
and observed how the few mutated cells were able to induce a response from its surrounding tissue.
Zev Gartner, Phd, the paper senior author, stated that he hopes to use this technology to study how changes in the structure of mammary glands can cause the destruction of tissue structure that is associated with tumors that metastasize.
#Mobileodt Brings Cervical cancer Diagnostics to Developing Countries Early detection significantly improves the survival rates for cervical cancer patients.
Cervical cancer used to be one of the leading causes of cancer deaths in the US,
but mortality rates have declined significantly in the last 40 years due in part to better compliance with regular cervical cancer screening.
and has leveraged this into a new cervical cancer screening product. Their cervical cancer screening system allows any smartphone to be turned into a colposcope,
making this part of the screening process readily available for most clinics. The hardware is equipped with a light source
and a member of MIT Koch Institute for Integrative Cancer Research, is the paper senior author.
and cancer drugs Longing to find a cure for cancer, HIV and other yet incurable diseases,
hepatitis and cancer. The research, led by Yury Stebunov, a scientist at the MIPT, was published in the ACS Applied materials & Interfaces.
and low-cost fabrication compared to sensor chips that are already commercially available. ur invention will help in drug development against viral and cancer diseases.
, 2015curcumin Nanodrug Breaks Cancers'Resistance to Treatment May 10th, 2015discoveries First theoretical proof: Measurement of a single nuclear spin in biological samples May 11th, 2015graphene holds key to unlocking creation of wearable electronic devices May 11th, 2015new Method to Produce Dual Zinc oxide Nanorings May 11th
, 2015curcumin Nanodrug Breaks Cancers'Resistance to Treatment May 10th, 2015announcements First theoretical proof: Measurement of a single nuclear spin in biological samples May 11th, 2015graphene holds key to unlocking creation of wearable electronic devices May 11th, 2015new Method to Produce Dual Zinc oxide Nanorings May 11th
, 2015curcumin Nanodrug Breaks Cancers'Resistance to Treatment May 10th, 2015interviews/Book reviews/Essays/Reports/Podcasts/Journals/White papers First theoretical proof:
, 2015curcumin Nanodrug Breaks Cancers'Resistance to Treatment May 10th, 2015artificial Intelligence Making robots more human April 29th, 2015lifeboat Foundation launches Interactive Friendly AI April 6th,
#Gold-diamond nanodevice for hyperlocalised cancer therapy: Gold nanorods can be used as remote controlled nanoheaters delivering the right amount of thermal treatment to cancer cells,
which can potentially be applied to thermal cancer therapy. Pei-Chang Tsai from the Institute of Atomic and Molecular Sciences, at the Academia Sinica, Taipei,
#Advance in photodynamic therapy offers new approach to ovarian cancer The findings were published just in the journal Nanomedicine:
and after further research may offer a novel mechanism to address this aggressive and often fatal cancer that kills 14,000 women in the United states each year.
Ovarian cancer has a high mortality rate because it often has metastasized into the abdominal cavity before it's discovered.
"Surgery and chemotherapy are the traditional approaches to ovarian cancer, but it's very difficult to identify all of the places where a tumor has spread,
and in some cases almost impossible to remove all of them, "said Oleh Taratula, an assistant professor in the Oregon State university/Oregon Health & Science University college of Pharmacy."
some tumors in laboratory animals began to regrow after two weeks. But with the addition of the combinatorial genetic therapy to weaken the cancer cell defenses,
there was no evidence of cancer recurrence. During the procedures, mice receiving the gene therapy also continued to grow
is associated with invasion, metastasis, resistance to cancer therapies, and overall cancer cell survival. That excess of DJ1 is silenced by the genetic therapy composed of sirna.
"Our study established a prospective therapeutic approach against ovarian cancer, "the researchers wrote in their conclusion."
"The tumors exposed to a single dose of a combinatorial therapy were eradicated completely from the mice
it also has broad implications for targeted therapy for other diseases such as cancer and neurological disorders,"said Chien.
#Portable Nanosensors Help Early Diagnosis of Breast cancer Tumors The nanosensor will be able to help the early diagnosis of breast cancer tumors even at very tiny dimensions after the completion of tests
The aim of the research was to facilitate the diagnosis of cancer tumors, including breast cancer, without the need for advanced clinical devices.
and simulated in this research for the early and easy diagnosis of breast tumors. The nanosensor consists of plasmonic nanoparticles that are placed at regular distance from each other.
the sensor is very sensitive to changes in electromagnetic fields that are dispersed with different tissues (normal and tumor.
The throughputs of waves are different through natural and tumor tissues. Therefore, the interaction of tissues with electromagnetic waves created by a similar electrical field ends in different results.
It means a non-consistency happens in the profile received from the interaction of emitted light and various healthy and cancer tissues.
The meaningful signal is a tool for the detection of tumor tissue e
#Pushing the limits of lensless imaging: At the Frontiers in Optics conference researchers will describe a custom-built ultrafast laser that could help image everything from semiconductor chips to cells in real time Using ultrafast beams of extreme ultraviolet light streaming at a 100,000 times a second, researchers
may aid efforts to build point-of-care devices for quick medical diagnosis of various diseases ranging from cancer, allergies, autoimmune diseases, sexually transmitted diseases (STDS),
#Scientists pave way for diamonds to trace early cancers Physicists from the University of Sydney have devised a way to use diamonds to identify cancerous tumours before they become life threatening.
synthetic version of the precious gem can light up early-stage cancers in nontoxic, noninvasive Magnetic resonance imaging (MRI) scans.
Targeting cancers with tailored chemicals is not new but scientists struggle to detect where these chemicals go since,
if a treatment has been taken up by a cancer. Led by Professor David Reilly from the School of Physics
researchers from the University investigated how nanoscale diamonds could help identify cancers in their earliest stages."
"By attaching hyperpolarised diamonds to molecules targeting cancers the technique can allow tracking of the molecules'movement in the body,
and target cancers long before they become life-threatening, "says Professor Reilly. The next stage of the team's work involves working with medical researchers to test the new technology on animals.
and cure bones damaged due to tumors, cysts or fractures. The use of bone replacement in various forms has increased in recent years.
New Option to Diagnose Leukemia Iranian researchers from Tarbiat Modarres University designed a biosensor that enables the early diagnosis of leukemia in the test sample by using naked eyes.
The aim of the research was to design an effective system to diagnose blood cancer (leukemia) by using gold nanobars.
and it may result in leukemia. Diagnosis tests are very time-consuming, expensive and difficult in some cases.
SNAS could be used to target anything from influenza to different forms of cancer. They also can be used to suppress the immune response
"Once developed fully, SNAS will lay the foundation for developing an entire new pipeline of drugs to treat a range of diseases, from psoriasis, lupus and rheumatoid arthritis to lymphoma, bladder cancer and prostate cancer."
the researchers found a significant decrease in tumor growth and a doubling of lifespan. The potency was up to an 80-fold increase over linear nucleic acids of the same sequence.
This observation has significant implications for treating liver cancer and cirrhosis patients.""The beauty of the approach is that a very small amount of drug does a tremendous amount of work,
scientists from the Helmholtz Zentrum Mnchen (HMGU) and the Ludwig-Maximilians-Universitt (LMU) in Munich have developed nanocarriers that site-selectively release medicines/drugs at the tumor site in human and mouse lungs.
In the journal, ACS Nano("Protease-Mediated Release of Chemotherapeutics from Mesoporous Silica Nanoparticles to ex Vivo Human and Mouse Lung Tumors"),the scientists reported that this approach led to a significant increase
in the effectiveness of current cancer medicines in lung tumour tissue. Tumor tissue in the lung.
Image: Sabine van Rijt, CPC/ilbd, Helmholtz Zentrum Mnchen) Nanoparticles are extremely small particles that can be modified for a variety of uses in the medical field.
#High-tech method allows rapid imaging of functions in living brain Researchers studying cancer and other invasive diseases rely on high-resolution imaging to see tumors and other activity deep within the body's tissues.
Using a new high-speed, high-resolution imaging method, Lihong Wang, Phd, and his team at Washington University in St louis were able to see blood flow, blood oxygenation, oxygen metabolism and other functions inside a living mouse brain at faster rates than ever before.
Given the importance of oxygen metabolism in basic biology and diseases such as diabetes and cancer,
#Scientists use nanotechnology to visualize potential brain cancer treatments in real time (Nanowerk News) Virginia Tech Carilion Research Institute scientists have developed new imaging techniques to watch dangerous brain tumor
and describes how the research team used nanotechnology to watch tumor stem cells respond to therapy. ee never been able to directly observe the actions of potential cancer treatments this way before,
a cancer biologist and an assistant professor of biomedical sciences and pathobiology at the Virginiaaryland College of Veterinary medicine. t was astounding.
Glioblastoma is a brain cancer with a poor prognosis. Even with surgical interventions or traditional treatments
and grow new tumors. lioblastoma tumors are hard to target, Sheng said. heye aggressive and resistant to therapeutics.
what is used in some cancer treatments and watched the process in cell cultures using in situ transmission electron microscopy.
whether we could isolate these types of toxic cells from the other brain tumor cells, while developing new imaging tools at the single-cell level to visualize the course of therapies needed to eradicate these cells,
or even test new cancer treatments at the cellular level, Kelly said. Sheng pointed to another characteristic that makes cancer cells difficult to treat:
In the same cancer population, even neighboring cells can differ drastically, and each cell can respond to treatments differently. e can look at single-cell delivery of cancer treatments,
and see how the individual cells respond, Sheng said. f we can learn how to kill these cells,
#Quick, easy and early diagnosis with rare earth ions Lack of oxygen in cells is an indicator of diseases as serious as cerebral haemorrhages, stroke and cancer.
#Molecular tinkering doubles cancer drug's efficacy The drug paclitaxel has been used for decades to fight breast, ovarian, lung and other cancers.
reducing its accumulation in tumors. Many molecular packaging systems have been developed to deliver the drug while counteracting these effects, with a protein-bound version of the drug called Abraxane currently the leading therapy.
the Duke team doubled tumor exposure to the drug compared to Abraxane while simultaneously reducing its effects on healthy tissue.
This kept mice with tumors alive significantly longer and, in some cases, completely eradicated the tumors.
The results were published online in Nature Communications on August 4, 2015("A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models".
and accumulate in tumors where they take advantage of a tumor's acidic environment.""The chemical bonds holding the polypeptide cage together are stable in blood,
but dissolve in a tumor's lower ph levels,"said Jayanta Bhattacharyya, senior researcher in Chilkoti's lab and first author on the paper."
"This delivers the drug directly to the tumor and helps prevent it from randomly absorbing into healthy tissue, reducing side effects."
A second group of mice had human prostate tumors growing under their skin. Similarly, while they did not survive past 60 days
the Duke technology showed a higher concentration of paclitaxel in the tumors with more staying power than Abraxane,
it could be a game-changer for cancer therapy.""In future work, Chilkoti and coworkers will begin applying the packaging system to other cancer drugs with the goal of developing a"one size fits all"technology to improve the effectiveness of many other cancer drugs s
such as applying anticancer medications to melanomas or applying growth factors and antibiotics for wound healing, says Jin Di,
or some cancer treatments, and can lead to a significantly higher risk of infections, and the need for blood transfusions.
however, drugs could be encapsulated in protein cages that accumulate inside of a tumor and dissolve once heated.
and cancer drugs Longing to find a cure for cancer, HIV and other yet incurable diseases,
hepatitis and cancer. The research, led by Yury Stebunov, a scientist at the MIPT, was published in the ACS Applied materials
"Our invention will help in drug development against viral and cancer diseases. We are expecting that pharmaceutical industry will express a strong demand for our technology,
"may aid efforts to build point-of-care devices for quick medical diagnosis of various diseases ranging from cancer, allergies, autoimmune diseases, sexually transmitted diseases (STDS),
The researchers say this approach also could be used for vaccines or immunotherapies for other conditions such as cancer or AIDS o
steel braces straighten crooked teeth, steel scalpels remove tumors. Most of the goods we consume are delivered by ships
Future applications of such a DNA walker might include a cancer detector that could roam the human body searching for cancerous cells
constantly computing whether a cancer is present.""More immediate practical applications may include deploying the DNA walker in the body
Although it may be a long march from diagnosing cancer to curing it, "All breakthroughs begin with baby steps.
and now is in the Chemical Biology laboratory at the National Cancer Institute. Also part of the study were researchers from Johns hopkins university School of medicine
using a transmission electron microscope at the National Cancer Institute to show how the fibers change
So just as nude mice can be really good models for cancer research, 'nude'versions of crop plants could also speed up agricultural research,
#How Chronic Inflammation Can Lead to Cancer Researchers discover how the immune system can create cancerous DNA mutations when fighting off infection.
or exposure to dangerous chemicals has long been linked to cancer, but exactly how this process takes place has remained unclear.
Now, a precise mechanism by which chronic inflammation can lead to cancer has been uncovered by researchers at MIT a development that could lead to improved targets for preventing future tumors.
the researchers unveil how one of a battery of chemical warfare agents used by the immune system to fight off infection can itself create DNA mutations that lead to cancer.
As many as one in five cancers are believed to be caused or promoted by inflammation. These include mesothelioma,
a type of lung cancer caused by inflammation following chronic exposure to asbestos, and colon cancer in people with a history of inflammatory bowel disease, says Bogdan Fedeles,
are the kind of lesions that would initiate cancer, he adds. DNA sequencing of a developing gastrointestinal tumor revealed two types of mutation:
cytosine (C) bases changing to thymine (T) bases, and adenine (A) bases changing to guanine (G) bases.
he explains. his scenario would best explain the work of James Fox and his MIT colleagues on gastrointestinal cancer.
or patterns of DNA mutations, associated with cancerous tumors. e believe that in the context of inflammation-induced damage of DNA,
says the paper provides a novel mechanistic link between chronic inflammation and cancer development. ith a combination of biochemical, genetic,
a type of mutation that is frequently observed in human cancers, Wang says. Studies of tissue samples of patients suffering from inflammatory bowel disease have found significant levels of 5clc,
who was honored with the prestigious Benjamin F. Trump award at the 2015 Aspen Cancer Conference for the research.
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