Visual impairments

Amblyopia (6)
Blindness (88)
Cataract (43)
Eye condition (5)
Optometrist (9)
Visual impairment (6)

Synopsis: Health: Illness: Visual impairments:


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and is the second leading cause of blindness worldwide. The goal is to develop time-release drugs that could replace daily administration of eye drops.

##The power of microneedles for treating eye conditions is the ability to target delivery of the drug within the eye##says Mark Prausnitz professor in the School of Chemical and Biomolecular engineering at the Georgia Institute of technology.##


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With nowhere else to go much of the excess glucose remains in the bloodstream where in high concentrations it can damage tissues throughout the bodyâ##potentially leading to blindness kidney damage cardiovascular diseases and other severe health problems.##


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#Oral med wakes up retinal cells so kids can see Tests of a new oral medication show the drug can improve vision in children with an inherited disease that can cause complete blindness

and is currently untreatable. his is the first time that an oral drug has improved the visual function of blind patients with LCA (Leber congenital amaurosis),

Their blindness was caused by either mutations in the genes RPE65 or LRAT, leading to a serious defect in the retinoid cycle.

which was funded by QLT Inc, the Foundation Fighting Blindness Canada, the Canadian Institutes of Health Research, the Fonds de recherche du Québec-Santé,


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The sensor would be embedded with an artificial lens during cataract surgery and would detect pressure changes instantaneously,

If you can fit this sensor device into an intraocular lens implant during cataract surgery it won require any further surgery for patients.

a group of diseases that damage the eye optic nerve and can cause blindness. Right now there are two ways to check eye pressure,

MARTERLENSES But if ophthalmologists could insert a pressure monitoring system in the eye with an artificial lens during cataract surgeryow a common procedure performed on 3 million to 4 million people each year to remove blurry vision

Shen says. e want every surgeon who does cataract surgeries to be able to use this.

The team has tested successfully the sensing device embedded in the same flexible silicon material that used to create artificial lenses in cataract surgeries.

and ultimately blindness. ftentimes damage to vision is noticed late in the game, and we can treat patients effectively

Both cataracts and glaucoma affect a similar aging population so it seems a natural pairing to place a pressure monitoring device in a new lens during cataract surgery.

MAKING IT COST-EFFECTIVE The team is working on downscaling the prototype to be tested in an actual artificial lens.


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#DNA sequencing reveals six new forms of blindness Scientists have discovered six new forms of inherited blindness,

which multiple members were blind from birth due to conditions such as Leber congenital amaurosis, cone-rod dystrophy,

Inglehearn says. ince new therapies are often specific to particular forms of inherited blindness, it is essential for each patient to know which condition they have,


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One common problem for example is presbyopia a type of farsightedness in which the ability to focus on nearby objects is diminished gradually as the aging eyes lenses lose elasticity.

which was developed at UC Berkeley works by adjusting the intensity of each direction of light that emanates from a single pixel in an image based upon a user s specific visual impairment.


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causing a wide range of problems that include extreme fatigue, dementia, stunted growth, deafness, blindness, multi-organ failure, and even death.


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#3d printed eye cells could one day cure blindness Researchers have printed actually viable retina cells using an inkjet printer.

Living, 3d printed retina cells could someday aid in curing many#kinds of blindness.####At the University of Cambridge, researchers have pulled off something of a 3d printing coup.


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Developers had to overcome unusual challenges to help people with visual impairments move their reading fingers along a straight line of printed text that they could not see.


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in a clinical study set to start this year on the eye condition known as macular degeneration. Other ministries have jumped also on the ips-cell bandwagon.


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these are showing early evidence that a product made from human ES cells can help to rebuild the layer of cells that support photoreceptors in the eyes of people with certain types of blindness.


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System gives hope to those blinded by a rare genetic eye condition called advanced retinitis pigmentosa, which damages the light-sensitive cells that line the retina.


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#Eye drops could dissolve cataracts Cataracts cloud the eyes of tens of millions of people around the world and nearly 17.2%of Americans over the age of 40.

or scalpels cut away the molecular grout that builds in the eye as cataracts develop, and surgeons sometimes replace the lens.

But now, a team of scientists and ophthalmologists has tested a solution in dogs that may be able to dissolve the cataract right out of the eye lens.

Though scientists don fully understand how cataracts form, they do know that the ogoften seen by patients is a glob of broken proteins,

causing the signature teamy glassvision that accompanies cataracts. Coming up with a solution other than surgery has been tough.

Her team came up with the eye drop idea after finding that children with a genetically inherited form of cataracts shared a mutation that stopped the production of lanosterol, an important steroid in the body.

the adults produced lanosterol and had no cataracts. So the researchers wondered: What if lanosterol helped prevent

or reduce cataracts? The team tested a lanosterol-laden solution in three separate experiments. First, they used human lens cells to test how effectively lanosterol shrank lab models of cataracts.

They saw a significant decrease. Then, they progressed to rabbits suffering from cataracts. At the end of the 6-day experiment, 11 of 13 rabbits had gone from having severe or significant cataracts to mild cataracts or no cataracts at all.

Finally, the team moved on to dogs, using a group of seven, including black Labs, Queensland Heelers,

and Miniature pinschers with naturally occurring cataracts. The dogs responded just as the researchers hoped to the lanosterol solution,

which was given in the form of both eye injections and eye drops. The dogslenses showed the same type of dissolving pattern as the human and rabbit lens cells.

The improvement was remarkableesearchers could tell just by looking at the dogseyes that the cataracts had decreased.

He has been investigating cataract proteins since 2000. hey discovered the phenomena and then followed with all of the experiments that you should dohat as biologically relevant as you can get. uben Abagyan,


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In people with a disease called retinitis pigmentosa, cones slowly atrophy, eventually causing blindness. Friedrich Miescher Institute scientists Botond Roska and Volker Busskamp have shown previously that some vision can be restored in mice by engineering those cone cells to express light-sensitive proteins.


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which can cause blindness. ndothelial cells play a very important role in multiple steps of many diseases, from initiation to the onset of clinical complications,


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According to TAU doctoral student and research team member Dr. Lilach Bareket there are already medical devices that attempt to treat visual impairment by sending sensory signals to the brain.


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ARMD is in fact the greatest cause of blindness in people over the age of 50


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which could improve vision in older people with presbyopia and cataracts. As people age, their lenses lose flexibility and elasticity.

This leads to a condition known as presbyopia, common in people over 45 years old, and can require optical aids, such as reading glasses.

The lens could also have application in tackling cataracts-the clouding of natural lenses -which affect many people in later life and


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Their eyes have caused defects largely by refractive errors, cataract, or glaucoma. They don see the world as the rest of the seeing world does and, due to the high costs of healthcare or unavailability of medical facilities,

they probably never will. 80%of all visual impairment can be prevented or cured, but 90%of these people live in developing countries,

Earlier in May, he delivered a talk at TEDX Auckland on his journey in fighting for preventable blindness


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Scientists at the Indian Institute of Science (IISC), Bangalore, have announced the development of a new and simple method to detect glaucoma early enough to prevent blindness.


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which can be a complication of cataract surgery. The company envisions a wide application of this immunodepletion strategy in other fibrotic diseases and cancer,

a disease that typically occurs in approximately 30%of adults and greater than 70%of children after cataract surgery.

Additional studies testing this formulation in rabbits undergoing cataract surgery are ongoing with Drs. Liliana Werner and Nick Mamalis, Co-Directors of the Intermountain Ocular Research center at the University of Utah.


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#Ubisoft offers new video game it says can treat lazy eye The Montreal-based gaming company Ubisoft has developed a video game it says could be used to treat amblyopia, also known as lazy eye.

Amblyopia is a condition in children where vision in one eye does not develop properly.

The company says it's the first video game based on a patented method for the treatment of amblyopia.


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and can even lead to blindness, "said the study's corresponding author Richard L. Sidman, MD, an investigator in the Department of Neurology at BIDMC and Bullard Professor of Neuropathology (Neuroscience), Emeritus, at Harvard Medical school.


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Eye and Ear clinicians and scientists are driven by a mission to find cures for blindness, deafness and diseases of the head and neck.


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such as nearsightedness, farsightedness, and astigmatism. The app then displays the refractive powers, axis of astigmatism,

and pupillary distance required for eyeglasses prescriptions. In July, the startup launched Blink, an on-demand refractive test service in New york,

According to the World health organization, uncorrected refractive errors are the world second-highest cause of blindness. Eyenetra originally invented the device for the developing world specifically


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Cataract and External Eye diseases at Johns Hopkins. About 60 to 80 percent of patients dont take medicine the way they are supposed to.


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when the sensing of light overlaps within these conesnchroma glasses allow wearers with red-green color blindness to see color again.

the MCA Chicago is making a move that might inspire other museums to increase accessibility for visitors with color blindness h


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and Strabismus (AAPOS) describes the effectiveness of a new computer-based vision-screening test, the Jaeb Visual acuity Screener (JVAS),

who then received a complete eye examination by an optometrist, which served as the study gold standard.

The examining optometrist was kept unaware of the initial JVAS vision screening results. No children who already wore glasses,

had been treated for amblyopia, or had undergone ocular surgery were included in the screening. The average screening time was 84 seconds, with a range of 23 to 357 seconds across all age groups.

Of the 65 children failing the gold standard examination, 86%failed for reduced visual acuity (56), 35%for hyperopia (23), 23%for astigmatism (15), 11%for anisometropia (7), 9%for myopia (6),

and 5%for strabismus (3), with some patients failing the gold standard for more than one reason.

For the 56 children with reduced visual acuity, the primary cause assigned hierarchically was uncorrected refractive error in 31 of 56 (55%),unilateral amblyopia in 7 (13%),bilateral amblyopia in 8 (14%


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"Battling parasitic wormsriver blindness is transmitted through the bite of blackflies and is the second leading cause of infectious blindness worldwide.

Lymphatic filariasis, spread by mosquitoes, leads to elephantiasis, a condition marked by painful, disfiguring swelling in parts of the body.


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Arrayin 2004, professor Petter Strømme examined a child with congenital cataract, growth delay and symptoms from the brain, the peripheral nervous system,


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increasing the risk of blindness, nerve damage, stroke, heart disease and several other serious health conditions.


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ARMD is in fact the greatest cause of blindness amongst people over the age of 50


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and is the second-leading cause of infectious blindness worldwide. Lymphatic filariasis, spread by mosquitoes, leads to elephantiasis, a condition marked by painful,


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even though there will always be a hole in your visual field. he neuroscientists at UQ School of Psychology may have opened the way to new treatments for the developed world leading cause of blindness,

but this has proved sufficient to bring about a 10 per cent reduction in functional blindness,

suggesting that the improvement wasn simply a matter of practising the task. e did not confidently expect to see much reduction in functional blindness,

it might prove similarly effective in other cases of blindness or be used to assist developing technologies,


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ARMD is in fact the greatest cause of blindness amongst people over the age of 50


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#New mechanism that can lead to blindness discovered An important scientific breakthrough by a team of IRCM researchers led by Michel Cayouette Phd is being published by The Journal of Neuroscience.

These findings could have a significant impact on our understanding of retinal degenerative diseases that cause blindness.

This is important because the death of photoreceptor cells is known to cause retinal degenerative diseases in humans that lead to blindness.

and Leber's congenital amaurosis by providing novel drug targets to prevent photoreceptor degeneration concludes Dr. Cayouette.

According to the Foundation Fighting Blindness Canada millions of people in North america live with varying degrees of irreversible vision loss


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and that lack of control leads to devastating complications from blindness to loss of limbs.


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see cataracts, and offer visual acuity tests as well as color and contrast tests. The project is led by Dr. Andrew Bastawrous

In a TED Talk, Dr. Bastawrous described his research into helping developing areas receive better eye care including the restoration of sight through cataract removal and prescription lenses.

The creators note that 80 percent of blindness worldwide is preventable but the tools necessary to address eye problems in the field are heavy, clumsy,

It also addresses color blindness through similar means. This is obviously not for consumers, but it will enable doctors


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and if you have any eye conditions. You calibrate your screen by measuring a credit card and sync your phone as a remote control for your computer over Wi-fi and an SMS confirmation.


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and a detail of a Vincent Van gogh self-portrait and applied algorithms that warped the image by taking into account the specific eye condition it was told to account for.


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#Researchers find new way to treat diabetic blindness WASHINGTON: US researchers said they have found a new way to restore the eyesight in patients who have a blinding eye disease caused by diabetes.

damaging the light-sensitive retina and causing blindness. Forty to 45 percent of Americans with diabetes have diabetic retinopathy, according to the US National Eye Institute.

damaging the light-sensitive retina and causing blindness. Forty to 45 percent of Americans with diabetes have diabetic retinopathy, according to the US National Eye Institute.


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Perfect for use in third world countries and remote locations far from medical help, this kit essentially consists of a 3d printed add-on for smart phones that can be used to treat preventable blindness.

it has the potential to help more than 39 million people around the world who lack access to basic optical healthcare. 0%of this blindness is avoidable,

Think about eye diseases like cataracts, glaucoma and others. While equipment for diagnosing such diseases already exist


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The most serious is that in the long term hyperglycemia provokes retinal damage that can lead to blindness renal insufficiency, destruction of nerve fibers or


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#Nanotechnology Drug in Droplets for Painless Treatment of Secondary Blindness The Mexican company"Medical and Surgical Center for Retina"created a way to transport drugs,

in order to avoid risks and painful treatments in people with secondary blindness due to chronic degenerative blindness such as diabetic retinopathy and degeneration of the eye.

and prevent blindness.""It is the most important prize delivered by the Presidency of the Republic in the area of`technology and innovation.

and prevent blindness. Source: http://www. invdes. com. mx


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#MEMS Innovations Enable Commercialization of Implantable Microchips for Drug-Delivery An implantable, microchip-based device may soon replace the injections


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Oxygenation at too high a level can cause damage to the retina, and blindness.""If we can contribute to better monitoring and stabilisation of oxygenation supply,


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"Injecting the wrong amount of medication can lead to significant complications like blindness and limb amputations,


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The vast majority of the millions of blindness cases worldwide can be treated whether it uncorrected refractive errors, cataracts or glaucoma, according to the World health organization.

The PEEK team, who recently presented their app at a TED Talk, said getting the examination tool to the low-income areas could benefit millions of the sightless. t is incredibly simple,


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njecting the wrong amount of medication can lead to significant complications like blindness and limb amputations,


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'And he continued it was'as painless and gentle'as cataract surgery. Visual acuity-or the ability to see fine spatial details-is measured typically with a Snellen chart used by optometrists globally.

The chart displays letters that get progressively smaller in size. The benchmark, and vision that is considered healthy and'normal,

Legal blindness is categorised as 20/200. On the opposite scale, 20/15 offers enhanced vision.

The lens-glasses combination was designed to help restore the sight of people suffering from age-related macular degeneration, or blindness.


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In particular, they were designed to restore the sight of people suffering from age-related macular degeneration, or blindness.


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The technique has had positive clinical results recently in conditions ranging from blood diseases to blindness.''We are somewhat late in the auditory field but


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Incredible Technology Our glasses are packed with sophisticated technology designed to support people with legal blindness. esight is hands-free, mobile,


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It may one day be used to reverse acquired blindness, alter pain thresholds and even hit the rest button on our biological clocks.


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and to have the opportunity to help a great deal more people living with blindness, "says Second sight's Executive officer, Dr. Robert Greenberg."


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and has restored already the sight of people with a specific form of blindness. About 200,000 people in the US have inherited diseases that cause problems for the photoreceptors in their eye.


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whose speed and precision make them useful for cataract and other eye surgeries. A femtosecond is one-quadrillionth,


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njecting the wrong amount of medication can lead to significant complications like blindness and limb amputations,


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Scurvy Anemia Infertility Arteriosclerosis Artherosclerosis Cataracts Glaucoma Nosebleeds Fatigue Infection Gingivitis Gastrointestinal problems Gallstones Dermatitis Impaired hormones Low insulin production


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which lead to blindness. he protocol developed here allows us to generate retinal tissue that closely resembles the biological retina with high efficiency and stability,


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immediate results will be obtained. e start off the fact that it is much cheaper to prevent than to cure blindness. he app also has utility in rural communities,


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It's obviously better and cheaper to prevent blindness rather than try to cure it so an app on a cellphone that just needs to focus on the eye is better in all ways.


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and is already in use in human gene therapy trials for blindness, heart disease, muscular dystrophy and other conditions.


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Invented by an optometrist in Canada, the Ocumetics Bionic Lens promises to enhance eyesight to a level that's three times better than 20/20-the universal standard for normal vision.

though-the lens developed by Gareth Webb is inserted into the eye via a painless procedure that takes less than 10 minutes (Webb says the process is a lot like cataract surgery).

so you'll never have a problem with cataracts or failing vision no matter how long you live.


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#A new smartphone attachment could save you a trip to the eye doctor You might think nothing of a trip to the optometrist,

The World Health Organisation (WHO) estimates that 80 percent of visual impairments suffered worldwide could be prevented

you can essentially carry an optometrist's fundus camera around in your back pocket.""Conduct routine eye examinations and retinal screenings anywhere for possible detection of a variety of disorders, including the leading causes of blindness-cataracts, glaucoma, diabetic retinopathy and age-related macular degeneration,

"the inventors explain on the project's official site. The gadget has been developed by ophthalmologist Andrea Russo together with and Italian tech development firm Si14 Spa.

It can compensate between-10d myopia (nearsightedness) to+10d hyperopia (farsightedness. At the moment the lens costs#400 (AUD$800) with the bumper attachment selling individually for#40 (AUD$80),

and get the results back to a professional optometrist-the idea is that the expert eye doctor can see more patients more quickly without leaving the office or waiting for appointments.

and get it into the hands of people who can't make it to the optometrist clinic-that could be


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"Injecting the wrong amount of medication can lead to significant complications like blindness and limb amputations,


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Current estimates by optometrists suggest that up to 90 percent of patients with concussions or blast injuries exhibit dysfunction in their eye movements.


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#Genetic discovery about childhood blindness paves way for new treatments Finding genes for retinal degenerations has immediate benefits for people living with blindness and vision loss, their families,

When 11 year old Naomi Lalandec walked into Dr. Robert Koenekoop's clinic at the Montreal Children's Hospital of the Mcgill University Health Centre (MUHC) with blindness and dwarfism due to

Comparing her genome to others with OMS and Leber congenital amaurosis (LCA), another form of childhood blindness, uncovered a new gene that is critical for vision.

What makes this breakthrough exceptional is that it opens up new treatment avenues for OMS and LCA and potentially other retinal degenerative diseases."

"With ongoing support from the Foundation Fighting Blindness (FFB), Canada's largest charity supporting vision research, Dr. Koenekoop has spent more than a decade searching for genes linked to blindness.

and Dr. Cayouette,"said Dr. Mary Sunderland, Director of research & Education at the Foundation Fighting Blindness."

which will be essential to study how manipulating phospholipids could generate innovative strategies to treat blindness n


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#Key discovery to preventing blindness stroke devastation Studying the eye and the brain might hold the key to creating therapeutic solutions for blindness stroke

and other seemingly unrelated conditions associated with the central nervous system notes Dr. Bazan. The eye is a window to the brain.


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Once it starts, the loss of vision is relentlessly progressive, often ending in blindness. In the journal Investigative Ophthalmology & Visual Science, UTHEALTH's Stephen P. Daiger, Ph d,


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whose speed and precision make them useful for cataract and other eye surgeries. A femtosecond is one-quadrillionth,


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000 Americans and causes slow vision loss that eventually leads to blindness. The Argus II system was designed to help provide patients who have lost their sight due to the disease with some useful vision.


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and is already in use in human gene therapy trials for blindness, heart disease, muscular dystrophy and other conditions.


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brain disorders, blindness and muscular dystrophy. MITOCHONDRIAL DNA is separate from DNA found in the cell nucleus and does not affect human characteristics such as hair or eye color, appearance or personality traits."


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njecting the wrong amount of medication can lead to significant complications like blindness and limb amputations,


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#Pioneering gene therapy takes aim at inherited blindness Canada first human gene therapy trial for eyeshe replacement of a faulty gene with a healthy ones now underway at the Royal Alexandra Hospital to preserve

and clinical research team leader. eople have hoped for this for a long time. horoideremia is a form of inherited blindness that affects one in 50,

Alberta Innovates (Alberta Innovation and Advanced education), The Foundation Fighting Blindness, Choroideremia Research Foundation Canada, and private donors.

It may also have relevance for other, far more common causes of blindness, such as retinitis pigmentosa and age-related macular degeneration. f we can maintain the vision our patients have,


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and is already in use in human gene therapy trials for blindness, heart disease, muscular dystrophy and other conditions.


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#Tasty Visuals To help those with visual impairments make out the shape and movement of objects, a company has developed a device that takes visual information


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