Synopsis: Health: Medicine:


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. Lai Fellowship, an Astrazeneca Distinguished Graduate student Fellowship, the National Institute of General Medical sciences, and the National institutes of health M


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a professor of radiation oncology at Harvard Medical school and Massachusetts General Hospital. ur knowledge about the abundance of extracellular matrix proteins in tumors has been limited.


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and colonoscopy used in the developed world are too costly to be implemented in settings with little medical infrastructure.

and Institute for Medical Engineering and Science is the senior author of a paper describing the particles in the Proceedings of the National Academy of Sciences the week of Feb 24.

The research was funded by a National Science Foundation Graduate Research Fellowship a Mazumdar-Shaw International Oncology Fellowship the Ruth L. Kirschstein National Research Service Award from the National institutes of health


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Stocker says in some cases that phenomenon could lead to new approaches to tuning flow rates to prevent fouling of surfaces by microbes potentially averting everything from bacteria getting a toehold on medical equipment to biofilms causing drag on ship hulls.

Guasto says the new understanding could help in the design of medical equipment to reduce such infections:

Since the phenomenon peaks at particular rates of shear he says Our results might suggest additional design criteria for biomedical devices which should operate outside this range of shear rates when possible either faster or slower.


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Surgeons use this procedure, known as entinel lymph node mapping, to determine the extent of cancer metastasis after removing a tumor.

a professor of dermatology at University Hospital Zurich who was not part of the research team. oth the effect on the stimulated immune responses


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Davide Zaccagnini a vascular surgeon and program manager for the Science Monks and Technology Leadership Program says he was motivated to join because


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The researchers, including senior author Bruce Volpe of the Feinstein Institute for Medical Research in Manhasset, N y,

a professor of physical medicine and rehabilitation at the University of California at Irvine. obotic measurements will help us identify promising treatments with smaller numbers of patients


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Two of their collaborators at MEEI Konstantina Stankovic, an ear surgeon who co-led the study with Chandrakasan,

Lustig points out that the new cochlear implant would require a more complex surgery than existing implants do. current cochlear-implant operation takes an hour, hour and a half,

he says. y guess is that the first surgeries will take three to four hours.


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or neurodegenerative diseases. his is the first time that MEG and fmri have been connected in this way, giving us a unique perspective,


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and medical conditions, including types of conditions that may be most readily treatable in primary-care situations. n no case were we able to find any subpopulations,

however, suggest nuances to the current debates over the expansion of Medicaid, medical costs, and the role of emergency rooms in providing care.

reduces out-of-pocket expenses or unpaid medical debt; and increases self-reported good health. In a 2013 paper published in the New england Journal of Medicine,

they showed that Medicaid coverage reduces the incidence of depression but does not produce measured improvements in physical health.


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Eric Perreault, a professor of biomedical engineering and physical medicine and rehabilitation at Northwestern University, says the group findings present the first insight into how muscle activation alters the ankle mechanical properties over its normal range of motion,


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while recovering from surgery or takes certain medications. There is no fast and easy way to diagnose these clots which often remain undetected until they break free

and Institute for Medical Engineering and Science (IMES). Lead authors of the paper are Kevin Lin a graduate student in chemical engineering and Gabriel Kwong a postdoc in IMES.

Another application is monitoring patients who are at high risk for a clot for example people who have to spend a lot of time in bed recovering from surgery.

when they go home after surgery. If a patient is at risk for thrombosis you could send them home with a 10-pack of these sticks

The research was funded by the Koch Institute Frontier Research Fund the Kathy and Curt Marble Cancer Research Fund the Mazumdar-Shaw International Oncology Fellows Program the Burroughs Wellcome


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The technology was described in a paper published last year in the journal Science Translation Medicine,

and heart disease and a lack of permanent oatingsfor medical implants that might help these patients.

In the Science Translation Medicine paper, the cofounders exposed polysb-modified catheters to blood for 60 days.


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a former postdoc in MIT Laser Biomedical Research center (LBRC) and one of the lead authors of a paper describing the technology in the Oct 2 issue of the journal Scientific Reports.

The research was funded by the National Institute of Biomedical Imaging and Bioengineering and Nanoscope Technologies, LLC n


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and Gregory Kato of the Department of Medicine at the University of Pittsburgh. Squeezing by People with sickle cell disease,


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with the long-term goal of establishing a new paradigm for treating obesity that could be applied to other neuropsychiatric disorders.


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that too much protein synthesis downstream of mglur5 activation gives rise to many of the psychiatric and neurological symptoms of fragile X. Bear lab tested this idea in mice,

This research was supported in part by the Howard Hughes Medical Institute, the National institute of mental health, the Simons Foundation, the Simons Center for the Social Brain at MIT,


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#MIT researchers design tailored tissue adhesives After undergoing surgery to remove diseased sections of the colon, up to 30 percent of patients experience leakage from their sutures,

Many efforts are under way to create new tissue glues that can help seal surgical incisions

a research scientist at MIT Institute for Medical science and Engineering (IMES) and senior author of a paper describing the findings in the Jan 28 online edition of Science Translational Medicine. e present a new paradigm by

Detailed study of tissue and biomaterial interactions can open a new chapter in precision medicine,


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In that study, published in a 2012 issue of Science Translational Medicine, microchips were implanted into seven elderly women,


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from environmental remediation to medical analysis. The polymers are synthesized at room temperature, and don need to be prepared specially to target specific compounds;

offering the example of a cheap testing kit for urine analysis of medical patients. The study also suggests the broader potential for adapting nanoscale drug-delivery techniques developed for use in environmental remediation. hat we can apply some of the highly sophisticated,

and an expert in nanoengineering for health care and medical applications. hen you think about field deployment,


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It could help medical professionals diagnose disease and identify the boundaries of tumors.""This nanoparticle may open the door for new'hypermodal'imaging systems that allow a lot of new information to be obtained using just one contrast agent,

new tool for medical imaging,"says Prasad, also a SUNY Distinguished Professor of chemistry, physics, medicine and electrical engineering at UB."

""Another advantage of this core/shell imaging contrast agent is that it could enable biomedical imaging at multiple scales, from single-molecule to cell imaging,


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a new type of nanoscale surface that bacteria can't stick to holds promise for applications in the food processing, medical and even shipping industries.

Finding low-cost solutions to limiting bacterial attachments is key, especially in biomedical and food processing applications."

and are tricky to remove in biomedical clean rooms and in equipment parts that are hard to reach or clean,


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The new tool could be used as a high-throughput screening platform to identify patients at risk of developing the urologic condition.


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#Researchers find exposure to nanoparticles may threaten heart health Nanoparticles extremely tiny particles measured in billionths of a meter are increasingly everywhere and especially in biomedical products.

Their study is published in the December 2014 issue of Environmental Toxicology. The research team was comprised of scientists from the Technion Rappaport Faculty of medicine Rambam Medical center

Products that use silica-based nanoparticles for biomedical uses such as various chips drug or gene delivery and tracking imaging ultrasound therapy and diagnostics may also pose an increased cardiovascular


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and could be as revolutionary to modern medicine as its twentieth century predecessor r


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#Scalable growth of high quality bismuth nanowires Bismuth nanowires have intriguing electronic and energy harvesting application possibilities.


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with biomedical electronic and photonic applications. The new technique is significantly less expensive than conventional methods


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This chemical damages nerve cells and apparently plays a role in neurodegenerative diseases such as Alzheimer's and Parkinson's.

thus be practical both in medical research as well as for diagnosis. The conversion of hydrogen peroxide to water,


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We could compare preservation of cultural heritage to medicine where the works of art play the role of the patients:

but must then be complemented by the development of medicines (advanced restoration materials) to cure the patient (restore the work of art).

One of the main advantages in using these fluids is that they exhibit a depressed eco-toxicological impact with respect to traditional solvent blends


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and IBM's T. J. Watson Research center have developed a prototype DNA reader that could make whole genome profiling an everyday practice in medicine.

Such technology could help usher in the age of personalized medicine where information from an individual's complete DNA


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This particular PTT treatment does not involve any medicine but only generates local heat within the tumor therefore posing much less side effects than the traditional chemo or radiation therapies.

Shi added that physicians are frustrated often with the current conventional means for early imaging of cancer cells through Medical Resonance Imaging


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Nanosilver is used also in biomedical applications toys sunscreen cosmetics clothing and other items. We were surprised to see significant upset of the human gut community at the lowest concentration of nanosilver in this study says Dr. Das.

Walker and Das utilized another Queen's discovery repoopulate created by Elaine Petrof (Medicine. repoopulate is a synthetic stool substitute


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#Paper electronics could make health care more accessible Flexible electronic sensors based on paper an inexpensive material have the potential to some day cut the price of a wide range of medical tools from helpful robots


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Hydrogels are used biodegradable materials in a number of biomedical applications because of their compatibility with the body and its processes.

"These 2d, silicate nanoparticles are unprecedented in the biomedical field, and their use promises to lead to both conceptual and therapeutic advances in the important and emerging field of tissue engineering, drug delivery, cancer therapies and immune engineering,


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Researchers synthesize platelet-like nanoparticles that can do more than clot blood (Phys. org) Stanching the free flow of blood from an injury remains a holy grail of clinical medicine.

Controlling blood flow is a primary concern and first line of defense for patients and medical staff in many situations from traumatic injury to illness to surgery.

This technology could address a plethora of clinical challenges said Dr. Scott Hammond director of UCSB's Translational Medicine Research Laboratories.

One of the biggest challenges in clinical medicine right now which also costs a lot of money is that we're living longer


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yielding insights into treatment for degenerative neurological conditions or restoring nerve connections after injury. Researchers at the University of Illinois at Urbana-Champaign and the University of Wisconsin-Madison created the microtube platform to study neuron growth.


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And more immediately they're already used in medical detectors for example the pregnancy tests you buy over-the-counter work use gold nanoparticles attached to antibodies.

Why are they good for medical detection? Nanoparticles have an extremely high surface area in relation to their volume.


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He is supported by faculty staff and Ph d. students in the Joint Department of Biomedical engineering a partnership between NC State and UNC-Chapel hill that tackles urgent biomedical problems.

The next step for nanodaisies is preclinical testing to determine whether they might be ready to fight cancer in humans.


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The wires could also be applied in the biomedical field to maximize heat production in hyperthermia treatment of cancer.


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-or even nanorobots could someday perform medical tasks in the human body. Researchers from the Max Planck Institute for Intelligent Systems in Stuttgart have taken now a first step towards this goal.

so that it can navigate through the human body enabling the crew to perform surgery in the brain.

and transporting a surgical team to a disease site will certainly remain fiction. Nevertheless tiny submarines that could navigate through the body could be of great benefit:

As in the case of their plastic micro-scallop the researchers also envision medical applications for their nanosubmarine.


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Published in Nature Nanotechnology researchers from Cardiff University have unveiled a new method for viewing nanodiamonds inside human living cells for purposes of biomedical research.

There is a growing consensus among scientists that nanodiamonds are one of the best inorganic material alternatives for use in biomedical research, because of their compatibility with human cells,


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Danny Porath, the Etta and Paul Schankerman Professor in Molecular Biomedicine at the Hebrew University of Jerusalem, reports reproducible and quantitative measurements of electricity flow through long molecules made of four


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and Jean-François Masson, an expert in biomedical instrument design, investigated how to simplify the measurement of methotrexate concentration in patients.


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Hersam a professor of materials science engineering chemistry and medicine at Northwestern University has developed a method to separate nanomaterials by size

That allows us to integrate electronics on flexible substrates like clothing shoes and wrist bands for real time monitoring of biomedical diagnostics and athletic performance.


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Kuzum emphasizes that the transparent graphene microelectrode technology was achieved through an interdisciplinary effort of CNT and the departments of Neuroscience Pediatrics and Materials science at Penn and the division of Neurology at CHOP.


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In addition to diagnosing medical conditions, the device could be modified to monitor environmental conditions for instance, identifying harmful airborne agents produced through automotive or chemical industry practices.


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The research which has been published in the journal Small drew on the medical expertise of Dr Neil Smyth and Dr Michael Ardern-Jones as well as contributions from physicist Professor Otto Muskens.


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Currently patients must frequently apply the medicine three times a day because of the eye's ability to self-cleanse a process that washes away 95 per cent of the drug.


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a field that uses biology to develop new tools for science, technology and medicine. The new study, published in print today in the journal Nano Letters,


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The new structures can lead to sensors and chips for future devices like smartphones computers and medical equipment.


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#Researcher develops optically traceable smart 2-D nanosheet that responds to ph Nanoparticles have the potential to revolutionize the medical industry

Using these optical properties to characterize the nanosheets Kim determined that he could approximate ph. Kim envisions biomedical engineers wrapping drugs inside of scrolled nanosheets

so that when the sheet unrolls it releases the medicine. PH responsive nanosheets for example could prove useful for targeting different parts of the human digestive tract


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Carbon nanotubes are rapidly becoming more common because of their usefulness in nanoelectric devices composite materials and biomedicine.


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The technology has extensive applications in medical equipment and national security since an electron beam is a critical component in generating X-rays.


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and medicines then you could transport the vesicle by creating a small opening and only allow the fuel to get out.


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#Nanotubes help healing hearts keep the beat (Phys. org) Carbon nanotubes serve as bridges that allow electrical signals to pass unhindered through new pediatric heart-defect patches invented at Rice university and Texas Children's Hospital.

This stemmed from talking with Dr. Pasquali's lab as well as interventional cardiologists in the Texas Medical center Jacot said.

and working with leaders in the biomedical field can really accelerate the path to adoption for these new materials.


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the method could be particularly useful for applications in optics, energy efficiency, and biomedicine. For example, it could be used to reproduce complex structures such as bone,


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This transformative technology enables highly specific low-power high-throughput physiological sensing that can be multiplexed to detect a number of significant disease-specific factors in real time commented Scott Hammond executive director of UCSB's Translational Medicine

In essence continued Hammond the promise of true evidence-based personalized medicine is finally becoming reality. This demonstration is said quite remarkable Andras Kis professor at École Polytechnique Fédérale de Lausanne in Switzerland and a leading scientist in the field of 2d materials and devices.


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and toxicology studies on the final product and get permission from the FDA to do human trials."


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despite surgical attempts to remove them and for leading to a dire prognosis for patients.

But scientists are developing a new way to try to root out malignant cells during surgery so fewer

Surgical removal is one of the main weapons doctors have to treat brain tumors. The problem is that currently there's no way to know

The techniques surgeons have at their disposal today are not accurate enough to identify all the cells that need to be excised.

Surgeons might be able to use the device in the future to treat other types of brain cancer they say.

Neuroscientists use lightwaves to improve brain tumor surgery More information: Guiding Brain tumor Resection Using Surface-Enhanced Raman Scattering Nanoparticles and a Hand-held Raman Scanner ACS Nano Article ASAPDOI:

10.1021/nn503948abstractthe current difficulty in visualizing the true extent of malignant brain tumors during surgical resection represents one of the major reasons for the poor prognosis of brain tumor patients.


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and chemists itching with excitement mesmerised by the possibilities starting to take shape from flexible electronics embedded into clothing to biomedicine (imagine synthetic nerve cells) vastly superior forms of energy storage (tiny


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Now researchers from the University of Surrey and Trinity college Dublin have treated for the first time common elastic bands with graphene to create a flexible sensor that is sensitive enough for medical use

and joint movement and could be used to create lightweight sensor suits for vulnerable patients such as premature babies making it possible to remotely monitor their subtle movements and alert a doctor to any worrying behaviours.


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Beyond catalysis, Ying predicts these new materials could be useful in electronics, chemical sensing and even biomedicine.


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This could get around a lot of serious health problems in neurodegenerative diseases in the future.""These disorders, such as Parkinson's, that involve malfunctioning nerve cells can lead to difficulty with the most mundane and essential movements that most of us take for granted:

which are affected in some neurodegenerative diseases. And it's at this level where the promise of Lieber's most recent work enters the picture.


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Patients must take medicine frequently and can suffer side effects since the contents of pills spread through the bloodstream to the whole body.

or used to coat permanent devices such as orthopedic implants. In tests the research team found that the diclofenac was released steadily over 14 months.


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energy storage and energy generation takes it a step closer to being used in medicine and human health.


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#World's smallest propeller could be used for microscopic medicine If you thought that the most impressive news in shrinking technology these days was smart watches,

The impact of these miraculous microscopic machines on medicine can only be imagined, but there is no doubt that it will be significant.

the real significance is how they might affect medicine.""One can now think about targeted applications,


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which is used now in the medical field to detect biomarkers in the early stages of disease.


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and for surgeons to then operate on it. We're now trying to add an extra optical signal

Dr Juan Gallo from the Department of Surgery and Cancer at Imperial College London said:"


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called plasmonic biosensors, could ultimately become a key asset in personalised medicine by helping to diagnose diseases at an early stage.

Personalised medicine is one of the new developments that is deemed to revolutionise health care. A key component is the detection of biomarkers, proteins in blood or saliva, for example,

nanotechnologists and biomedical researchers with the aim of developing a so-called plasmonic nanobiosensor for the detection of proteins.

because it will be a component of future medicine, "says Alexandre Brolo, professor of chemistry specialised in nanotechnology research,


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vaccinations, cancer imaging and other medical treatments. Currently, the predominant practice is using viruses for delivery to cells.


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The new technology also has major medical implications. Currently, memory used in computers and phones is made with silicon substrates, the surface on

To obtain medical information from a patient such as heart rate or brainwave data, stiff electrode objects are placed on several fixed locations on the patient's body.


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much like a medical X-ray CT SCAN. With the aid of special computer software researchers combine these images to form a three-dimensional picture,


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I believe this approach has significant value as a platform for more detailed investigations of realistic systems important for these new biomedical applications of DNA NANOPARTICLE pairings,


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"Nanoparticles are extraordinarily small particles at the forefront of advances in many biomedical, optical and electronic fields,


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Genetic testing can improve the treatment of such medical conditions. By combining our expertise in molecular diagnostics and nanotechnology,


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and nanometer scale is crucial from semiconductor electronics to biochemistry and medicine. Explore further: High-resolution microscopy technique resolves individual carbon nanotubes under ambient condition c


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in collaboration with colleagues at the University of Michigan, have developed a 3-D artificial enzyme cascade that mimics an important biochemical pathway that could prove important for future biomedical and energy applications.

"said Walter. The work also opens a bright future where biochemical pathways can be replicated outside the cell to develop biomedical applications such as detection methods for diagnostic platforms."


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enabling surgeons to better determine which tissue to remove and which to leave. Research by Jeremy Duczynski from the University of WA's School of Chemistry and Biochemistry investigated

whether the nanoparticles would work as effective optical contrast agents to provide an estimate of the size and shape of tumour margins during surgery.


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Recently biomedical researchers have found ways to increase the effectiveness of certain contrast agents by associating them with nanoparticles.


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treatment procedures in remote places with difficult access to hospitals or medical clinics. Although very compact (only a few square centimeters) the lab-on-a-chip hosts various sensing sites distributed across a network of fluidic micro-channels that enables it to conduct multiple analyses.

Quidant's research group at ICFO in collaboration with several groups of oncologists joined the worldwide effort devoted to the ultra-sensitive detection of protein markers located on the surface of cancer cells and in peripheral blood


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#Silly Putty material inspires better batteries Using a material found in Silly Putty and surgical tubing, a group of researchers at the University of California,


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or DNA sequence from one animal into the genome of another plays a critical role in a wide range of medical researchncluding cancer, Alzheimer's disease, and diabetes.


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and serve as energy-carrying wires in medical implants. Yuan Chen a professor of chemical engineering at NTU led the new study working with Dingshan Yu Kunli Goh Hong Wang Li Wei and Wenchao Jiang at NTU;

Such clothing could power biomedical monitoring devices a patient wears at home providing information to a doctor at a hospital Dai said.


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Associate professor Baohua Jia led a team of researchers from Swinburne's Centre for Microphotonics to create a micrometre thin film with record-breaking optical nonlinearity suitable for high performance integrated photonic devices used in all-optical communications, biomedicine


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#Preventing Superbugs By Deactivating Antibiotics With A Flash Of Light Bacterial resistance is becoming one of the most serious problems in the medical world


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and Android#that can be used for the detection of radioactivity in everyday life such as exposure on airplanes from medical patients or from contaminated products.


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Just last year, more than 200 people in Lahore died after contaminated cardiac medicines containing a toxic amount of an anti-malaria drug hit the city's supply.

and patients are desperate for affordable medicine. Consider this: The World health organization says that at least 10 percent to 30 percent of the pharmaceutical market in these countries is compromised."

"says Zaman, now a biomedical engineer at Boston University. The bogus-drug trade isn't just a problem for the world's poorest patients:

Zaman has made a cheap handheld scanner called Pharmacheck to quickly identify fake medicine in villages

But others, particularly those in developing countries, might contain an ineffective amount of medicine or release the right amount in the wrong way;

Too strong a signal right away could mean that the medicine wasn't made properly and is probably toxic.

Others contain an ineffective amount of medicine. Meanwhile, the FDA is ramping up deployment of its own handheld scanners,


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You also fail to mention just how many advances in modern medicine we were given by the Germans.

And yes a lot of medical breakthroughs came from the horrible experiments done by the Nazi's

and potentially getting new medicines to the people who need them more rapidly. Not to mention the potential applications of stem cell-derived organs in toxicology screens for new pharmaceutical compounds

in order to reduce the chances of severe side effects manifesting further down the line in real living people.

'there is enormous medical potential here and I think that to deny such potential for the individuals who will most benefit from it in future


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Remember the difference between a medicine and a poison is dose. I think the next question people should be asking


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Technology can solve many medical problems Viventi says. We just have to plug away and apply what we already know.#


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For#decades microfracture surgery#pricking holes in the knee bone to stimulate tissue#regrowth#was the gold-standard repair.

So many new procedures coming out are superior says orthopedist Joshua Harris who studied#microfracture s impact on the NBA.

#The Substitute that Deliversto fix a lesion doctors use osteochondral autograft transplant#surgery#(OATS)# to transfer cartilage from a non-load-bearing section of the patient s knee.#

#Riley Williams director of the Institute for Cartilage Repair at the Hospital for#Special Surgery says that unlike microfracture this method implants the collagen-rich hyaline necessary to continue competing at the highest level.#

The two-step process requires open surgery and up to a year of rehab which#dissuades some athletes.

It s difficult to convince people that an ACI is their best option says orthopedic surgeon Andreas Gomoll at Brigham and Women s Hospital even though it s a more durable fix than microfracture.

Because it s completed during a single surgery rehab time is minimal.##Similarly Neocart which is undergoing FDA trials implants collagen on a biodegradable scaffold.

#Once#good cartilage products become available microfracture could become obsolete says Charles Roth of the Andrews Institute for Orthopaedics and Sports Medicine.


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