Synopsis: Health: Illness: Nervous disorders:


impactlab_2013 00114.txt

##People with autism, who can have a hard time reading facial expressions, may be among the beneficiaries, Dr. Burleson said.


impactlab_2013 00222.txt

Wearable device mania has swept the whole world. An Australian research institute predicted that one fifth of Australians would have one wearable device each in the future year, with shipment reaching 36 million units.


impactlab_2014 00011.txt

Does it suggest a level of paranoia to want to be forgotten on the internet? Are we really revealing that much about ourselves that privacy has become something of an antiquated concept?


impactlab_2014 00070.txt

and she makes the stress melt away at the end of a long day. But Lucy isn t Mr. Petrone s girlfriend.

##If it s a friend or a girlfriend, there s always points in time where there could be stress within that relationship,


impactlab_2014 00288.txt

his could be a major step toward helping millions around the world who are suffering from Alzheimer disease and other dementias.

we may be able to counter dementias. In the human arm of the research, the scientists gave a whole battery of cognitive tests to over 700 people with and without the gene variant.

Although preliminary, they suggest that a form of klotho could be used to enhance cognition for people suffering from dementia.


impactlab_2014 00424.txt

Elevated p25 levels in the brain have been documented upon exposure to neurotoxic stimuli such as oxidative stress and beta amyloids. n this study


impactlab_2014 00484.txt

you don have to be clinically paranoid to find something worrying in the prospect of a highly automated warship that can be controlled by anyone who has the right login information.


impactlab_2014 00571.txt

#Researchers discover marijuana s anxiety relief effects Researchers at Vanderbilt University have found cannabinoid receptors, through

in a key emotional hub in the brain involved in regulating anxiety and the flight-or-fight response.

The discovery may help explain why marijuana users say they take the drug mainly to reduce anxiety,

he natural endocannabinoid system regulates anxiety and the response to stress by dampening excitatory signals that involve the neurotransmitter glutamate. hronic stress or acute,

severe emotional trauma can cause a reduction in both the production of endocannabinoids and the responsiveness of the receptors.

Without their ufferingeffect, anxiety goes up. hile marijuana xogenouscannabinoids also can reduce anxiety, chronic use of the drug down-regulates the receptors, paradoxically increasing anxiety.

This can trigger vicious cycleof increasing marijuana use that in some cases leads to addiction.

Patel said. ow can we see how that system is affected by stress and chronic (marijuana) use?


impactlab_2014 00639.txt

The special eyewear can potentially eliminate the need for follow-up surgical procedures and save patients from more stress and anxiety

inconvenience and anxiety. Dr. Achilefu, who also happens to be co-leader of the Oncologic Imaging Program at Siteman Cancer Center,


livescience_2014 04799.txt

Facet's applications are incredibly far-reaching from treating children with autism to play-testing video games.

Recognizing other people's emotions based on their facial expressions is a challenge for many people who have an autism spectrum disorder particularly children.

As a research professor at the University of California San diego's Machine Perception Lab Bartlett has been studying the use of facial recognition software to help people with autism for several years. 5 Controversial Mental health Treatments

This game helps children with autism recognize other people's emotions through their facial expressions as well as teaches them how to make facial expressions that express their own feelings.


mnn.com 2014 0000271.txt

resistance to stress and self-healing abilities could allow them to be used on airplane wings.


mnn.com 2014 0000358.txt

and when disorders like autism first take root researchers say. This is another installment in our suite of brain atlases to try to map how all genes are used across the brain

Allen Institute for Brain science) The map of a healthy developing brain also provides clues to the origin of developmental disorders such as autism the researchers said.

Other studies have revealed certain genes that are active in autism. Lein's team saw these genes were turned on in newly generated excitatory neurons

(which activate other neurons) in the prenatal cortex suggesting autism may start in the womb as opposed to later in life.


mnn.com 2014 0000481.txt

This stress was enough to make the cells pluripotent in as little as 30 minutes. Not only that they were more malleable than the ips cells developed back in 2006.

I would have thought never external stress could have this effect. The idea came from another biologist at the same facility Haruko Obokata who says it took her five years to persuade her colleagues that this technique would work.

The work ties into Obokata's other research into stress. As explained on her lab's web page All organisms possess instincts to survive exposures to external stresses by adapting to their environment and to some degree regenerating injured tissues or organs.


Nature 00024.txt

Those in hot, arid regions may be losing trees because of drought stress. Even if rainfall is stable,

and his team captured may be symptoms of climatic stress that make the forests more liable to such catastrophes."

"These changes in mortality rates are really an indication of overall system stress, and when trees are stressed,


Nature 00117.txt

"Claustrophobia is a widespread problem in clinical MRI, "says Pruessmann. Removing the coil from the machine provides a less constraining cavity.


Nature 00127.txt

Forget about it Current treatments for patients who have strong fearful memories, for example people with posttraumatic stress disorder (PTSD

"There are a lot of treatments for anxiety disorders but you see a lot of relapse, "says Kindt. In addition, the drug treatment didn't affect how well the participants remembered the link between the spiders and the shock.


Nature 00150.txt

#What causes schizophrenia?:Nature News Findings from a'brain training'study challenge theory. Researchers in Sweden have revealed a surprising change in brain biochemistry that occurs during the training of working memory,

The discovery may have implications for understanding disorders in which working memory is deficient such as schizophrenia and attention deficit hyperactivity disorder (ADHD.

"The density of neurotransmitter receptors is known to change in psychiatric disorders like schizophrenia, and this has been considered a cause of the diseases,


Nature 04422.txt

whose work at the Scripps Research Institute Molecular Screening Center in La jolla, California, led to a compound now in clinical trials for multiple sclerosis.


neurosciencenews.com 2015 0000117.txt

#Genetic Brain disorders Converge at the Synapse Several genetic disorders cause intellectual disability and autism. Historically, these genetic brain diseases were viewed as untreatable.

a treatment developed for one genetic cause of autism and intellectual disability might be useful for many others.

the Picower Professor of Neuroscience in MIT Picower Institute for Learning and Memory, showed that two very different genetic causes of autism

and autism is fragile X syndrome, which arises when a single gene on the X chromosome,

Different genes, same consequences Another cause of autism and intellectual disability is the loss of a series of genes on human chromosome 16,

Current research indicates that well over 100 distinct gene mutations can manifest as intellectual disability and autism.


neurosciencenews.com 2015 0000127.txt

Studies at other institutions have identified mutations in the gene for Syngap associated with autism and intellectual disability.


neurosciencenews.com 2015 000032.txt

such as multiple sclerosis (MS). e could also confirm previous findings, such as that the pyramidal cells of the cerebral cortex are organised functionally in layers,


neurosciencenews.com 2015 000068.txt

#What Autism Can Teach Us About Brain Cancer Both disorders involve faults in the same protein.

Applying lessons learned from autism to brain cancer, researchers at The Johns hopkins university have discovered why elevated levels of the protein NHE9 add to the lethality of the most common and aggressive form of brain cancer, glioblastoma.

A summary of their work in human tumor cells and mice will be published on Feb 9 in the journal Nature Communications. y laboratory research on cargo transport inside the cells of patients with autism has led to a new strategy

Rao research group previously showed that autism-associated defects in the protein NHE9 are harmful

Based on their autism research, the team suspected that the boost NHE9 gave to glioblastomas was explained by abnormal endosome acidity.

Further studies revealed that, in contrast to autism, NHE9 is overactive in brain cancer, causing endosomes to leak too many protons


news.discovery.com 2015 01435.txt.txt

#Brain-Sensing Headband Helps Users Manage Stress Technology and relaxation don always go hand in hand. However, a brain-sensing headband that reads brain waves

and manage stress. The Muse headband is lined with seven EEG sensors that detect the brain electrical activity

Users are asked then to participate in a three-minute guided exercise that aims to reduce stress, calm anxiety and increase focus and concentration.


newsoffice 00011.txt

Increased speed and higher voice tones for example are strong indicators of high stress levels. Readers placed around an office collect the data and push it to the cloud.

A study with Cornell University in 2013 for instance allowed the startup to prove that it could accurately predict high levels of cortisol in someone s saliva an indicator of high stress based on their tone of voice.


newsoffice 00025.txt

While IBD is the focus of the initial flagship project the center is designed to foster opportunities to explore the impact of the microbiome on systemic autoimmune diseases such as multiple sclerosis Type 1 diabetes arthritis and other disorders such as

autism obesity acne and allergies. The co-directors are presenting their research collaboration this week at an MGH-hosted conference on microbes metabolism and mucosal circuits.


newsoffice 00028.txt

can make towers almost twice as strong to handle stress.)Smith compares the process to today at home installation of rain gutters:


newsoffice 00160.txt

This circuit could offer a target for new drugs to help treat conditions such as posttraumatic stress disorder the researchers say In the future one may be able to develop methods that help people to remember positive memories more strongly than negative ones says Susumu Tonegawa the Picower

and posttraumatic stress disorder but the neural circuitry underlying such malleability is known not. In this study the researchers set out to explore that malleability with an experimental technique they recently devised that allows them to tag neurons that encode a specific memory or engram.

whether reactivating pleasant memories has any effect on depression in hopes of identifying new targets for drugs to treat depression and posttraumatic stress disorder.

and also has potential implications for treating mental illness. This is a tour de force of modern molecular-biology-based methods for analyzing processes such as learning and memory at the neural-circuitry level.


newsoffice 00169.txt

engineers can generate 3-D digital models of large structures to simulate how theyl fare under stress, vibrations, heat,

In one demonstration, for instance, a mining company used components available in the Akselos library to rapidly create a simulation of shiploader infrastructure complete with high-stress ot spotsthat needed inspection.

so they can visualize the stress, strain, and displacement in 3-D in their browser, he says. e think it a great way to show students the value of fast, 3-D simulations.


newsoffice 00202.txt

Still others could help children with autism better interact el Kaliouby says such as games that make people match facial cues with emotions.

Together they quickly started applying the facial-coding technology to autism research and training the algorithms by collecting vast stores of data.


newsoffice 00214.txt

#$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research The following is adapted from a press release issued today by the Broad Institute of MIT and Harvard.

The biological causes of mental illnesses such as schizophrenia and bipolar disorder have mystified scientists for decades; in the last five years however understanding has accelerated dramatically driven by advances in human genomics.

Because researchers cannot study the biochemistry of the living human brain the genes that predispose people to schizophrenia

and bipolar disorder represent the best way to gain molecular insights into these disorders. The discovery of specific genes associated with these disorders provides significant clues to their biological basis and points to possible molecular targets for novel therapies.

Since 2004 Ted Stanley and his late wife Vada Stanley have been instrumental to the progress made thus far in identifying the genetic risk factors for schizophrenia and bipolar disorder and the initiation of therapeutic efforts based on those discoveries.

Biomedical researchers have struggled for years to understand the molecular causes of serious ailments such as schizophrenia and bipolar disorder.

Yet in the past few years scientists have begun to find genes that shape the risk of schizophrenia bipolar disorder and other illnesses thanks in large part to Stanley s support.

and assembled the world s largest collection of DNA samples in psychiatric research currently more than 175000 samples including schizophrenia bipolar disorder autism attention deficit hyperactivity disorder and healthy control samples.

Analysis of 80000 of these samples so far by Broad researchers and collaborators has linked more than 100 genomic regions to schizophrenia

Significant efforts are ramping up in bipolar disorder autism and other conditions. We are going to illuminate the biology behind these conditions says Eric Lander founding director and president of the Broad Institute and a professor of biology at MIT.

If we know the biological causes we can begin to dispel the stigma around people battling mental illness

when his son Jonathan was stricken with severe bipolar disorder while in college. The first few years were difficult

but Jonathan overcame his illness with the help of lithium a landmark drug first used to treat patients with mental illness in 1949.

Now a successful attorney Jonathan is also a founding board member of the Treatment Advocacy Center a nonprofit organization dedicated to reforming laws that affect persons with a mental illness and an advocate for the National Alliance on Mental illness.

Although lithium helped give Jonathan a normal life other patients who suffer from mental illness have not been as fortunate.

He moved to the Broad Institute to tackle mental illness because he had a deep personal interest in the field.

Complete the list of all genes that play roles in severe psychiatric disorders including schizophrenia bipolar disorder autism and others.

To create a comprehensive catalog of the genetic variation that underlies mental illness the researchers plan to expand their international network

About the Stanley Center for Psychiatric Research The mission of the Stanley Center for Psychiatric Research at the Broad Institute is to reduce the burden of serious mental illness through research.

Stanley Center researchers focus on schizophrenia bipolar disorder autism attention deficit hyperactivity disorder and other neuropsychiatric disorders.


newsoffice 00365.txt

lowers joint stress; and drastically lowers the time required to acclimate to the prosthesis (which can take weeks or months with conventional models).

and experience greater musculoskeletal stress which causes joint osteoarthritis. The scientific and engineering research that ultimately led to today s Biom prosthesis was conducted by Herr s research group within the MIT Media Lab


newsoffice 00415.txt

as well as serve as plant-based biosensors and stress reducers. By adapting the sensors to different targets,


newsoffice 00493.txt

It could also shed light on processes that underlie conditions such as memory disorders or dyslexia, and could benefit patients suffering from paralysis


newsoffice 00612.txt

#Schizophrenia linked to abnormal brain waves Schizophrenia patients usually suffer from a breakdown of organized thought often accompanied by delusions or hallucinations.

Mutations in the gene for calcineurin have previously been found in some schizophrenia patients. Ten years ago MIT researchers led by Susumu Tonegawa the Picower Professor of Biology

these mice displayed several behavioral symptoms of schizophrenia including impaired short-term memory attention deficits and abnormal social behavior.

This pattern helps to explain some of the symptoms seen in schizophrenia the researchers say.

However this network is hyperactive in schizophrenic patients before and during tasks that require the brain to focus

Further studies of these mice could help reveal more about the role of the default mode network in schizophrenia Tonegawa says.


newsoffice 00623.txt

e found that there is a mechanism that can, in principle, close cracks under any applied stress,

shows a small crack (dark horizontal bar just right of bottom center) that mends itself as the metal is put under stress.

These defects have intense stress fields, which an be so strong, they actually reverse what an applied load would do,

it can heal. he stress from the disclinations is leading to this unexpected behavior, he says.

in conjunction with stress-driven grain boundary migration, could actually heal cracks. This is indeed provocative


newsoffice.mit.edu 2015 00005.txt

and anxiety. e need to study this circuit in more depth, but our ultimate goal is to develop safe,


newsoffice.mit.edu 2015 000067.txt

2015 SHARE Several genetic disorders cause intellectual disability and autism. Historically, these genetic brain diseases were viewed as untreatable.

a treatment developed for one genetic cause of autism and intellectual disability might be useful for many others.

the Picower Professor of Neuroscience in MIT Picower Institute for Learning and Memory, showed that two very different genetic causes of autism

and autism is fragile X syndrome, which arises when a single gene on the X chromosome,

Different genes, same consequences Another cause of autism and intellectual disability is the loss of a series of genes on human chromosome 16,

Current research indicates that well over 100 distinct gene mutations can manifest as intellectual disability and autism.


newsoffice.mit.edu 2015 000075.txt

coming to a sudden halt and putting stress on the threads, causing them to fail.

the sheller stopped at a more gradual pace, reducing thread stress. All shellers could then be modified,


newsoffice.mit.edu 2015 00682.txt.txt

releasing a bit of stress, and making it easier for a second atom to climb out of a trough


newsoffice.mit.edu 2015 00743.txt.txt

While conventional lithium-ion batteries are composed of brittle electrodes that can crack under stress the new formulation produces battery cells that can be bent,


newsoffice.mit.edu 2015 00762.txt.txt

for example, diabetes, cancer, multiple sclerosis, and osteoporosis. Now Microchips Biotech will begin co-developing microchips with Teva Pharmaceutical, the world largest producer of generic drugs,


phidgets.wordpress.com 2014 00001.txt

if the dog is under unusual stress or if a chronic health condition may be worsening.


phys.org 2015 000069.txt

Macrophages accumulation in the arterial wall under atherogenic conditions such as high cholesterol triglycerides oxidative stress#are converted into lipids or laden foam cells

and that they also increase oxidative stress and toxicity. A recent update from the American Heart Association also suggested that fine particles in air pollution leads to elevated risk for cardiovascular diseases.


phys_org 00006.txt

#'Trojan horse'proteins are step forward for nanoparticle-based anticancer and anti-dementia therapeutic approaches Scientists at Brunel University London have found a way of targeting hard-to-reach cancers


phys_org 00011.txt

but none reported so far can sense the direction of stress. This is the kind of information that can tell our bodies a lot about the shape

piezoresistive interlocked microdome arrays are employed for stress-direction-sensitive, stretchable electronic skins. Here we show that these arrays possess highly sensitive detection capability of various mechanical stimuli including normal,


phys_org 00237.txt

If there's a hole in the heart a patch has to take the full mechanical stress he said.


phys_org 00423.txt

#Supercomputers reveal strange stress-induced transformations in world's thinnest materials (Phys. org) Interested in an ultra-fast unbreakable and flexible smart phone that recharges in a matter of seconds?

and break under stress. Fortunately researchers have pinpointed now the breaking mechanism of several monolayer materials hundreds of times stronger than steel with exotic properties that could revolutionize everything from armor to electronics.

In this study DFT calculations revealed the materials'atomic structures stress values vibrational properties and whether they acted as metals semiconductors or insulators under strain.


phys_org 00482.txt

Ozden explained that the even distribution of stress along the belly-flopping nanotube which is many times longer than it is wide breaks carbon bonds in a line nearly simultaneously.


phys_org 00488.txt

Fan calls his approach"a simple stress-based fabrication method"that, when applied to nanoparticle arrays, forms new nanostructures with tunable properties."

This external stress manually induced transitions in the film that synthesized new materials, "he said.

The stress-induced synthesis processes are simple and clean. No thermal processing or further purification is needed to remove reaction byproducts r


phys_org 00507.txt

At the 90â°and 45â°impact angles on the other hand fewer atoms were involved in the impact so the stress was concentrated more on fewer atoms.


phys_org 00587.txt

what happens under stress. In most thin film transistors, the material starts to crack, which,


phys_org 00638.txt

The device was subjected to constant mechanical stress and its performance was evaluated. The fiber supercapacitor continues to work without performance loss even after bending hundreds of times Yu said.


popsci_2013 00141.txt

and stress response genes when they hear the courtship song of a male. This helps them fight off sexually-transmitted infection from the fungus Metarhizium robertsii.


popsci_2013 00238.txt

Zhang plans to use the techniques to study the genetics of autism and schizophrenia. He has begun already to insert genes linked to each disorder one by one into animal models to observe their effects.


Popsci_2014 00051.txt

#Building Better Knees For The NBA The stress of repetitive jumping makes NBA players#particularly prone to painful even career-ending cartilage lesions.


Popsci_2014 00207.txt

Kidding aside an app like this could help people with conditions such as autism that makes it hard for them to read emotions.


robohub 00022.txt

When an electric current is applied to one of the DEAS it creates a biased stress between the two DEAS thus bending the actuator.


robohub 00292.txt

However first jump up tests showed that the stress resulting from a sudden braking of the momentum wheel led to mechanical deformations of the momentum wheels and aluminium frame.

and breaking mechanism to reduce the mechanical stress caused by the jump up. In addition to balancing my colleagues are now investigating the use of controlled manoeuvres of jumping up balancing


robohub 00356.txt

The mechanical stress of loading and unloading and the corrosive properties of seawater all take their toll on a vessel#structure.


robohub 00416.txt

and (4) Monitoring dementia patients. Once standards are in place it will give a boost to full-scale production of nursing-care robots from all over the world but particularly from Japan n


R_phys.org 2015 00002631.txt

and facilitate the development of new drugs for diseases like cancer, stroke and dementia.""The simplicity is the strength of this technology.


R_phys.org 2015 00002633.txt

This puts tremendous stress on the connection point, a conical clamping ring. Furthermore, once the parts have been joined together,


R_phys.org 2015 00002934.txt

These noteworthy results were achieved by the non-destructive stress-relaxation ability of the unique electrodes as well as the good piezoelectricity of the device components.


R_phys.org 2015 00003203.txt

showing structural stress corrosion cracking and wing panel composite skin abnormalities, engineers have had to do extensive analysis to develop repairs."


R_profit.ndtv.com_news_banking-finance 2015 00042.txt.txt

Their anxiety is heightened only by the prospect of an imminent rise in U s. interest rates, which would draw capital away from emerging markets like China."


R_scitechdaily.com 2015 00655.txt.txt

This expansion and contraction of aluminum particles generates great mechanical stress, which can cause electrical contacts to disconnect.


R_techcrunch.com 2015 07701.txt.txt

and plan to launch versions of the app for multiple sclerosis and high cholesterol patients in the future. magine a patient has cancer,


R_techcrunch.com 2015 07880.txt.txt

Gomez Andonaegui found that the price fluctuated so much that it was major stress in running his business.


R_timesofindia.indiatimes.com_home_science 2015 01106.txt.txt

and the brain regions associated with dementia and it can help contribute to a dementia diagnosis. He noted that this also provides strong evidence that dementia in humans could be called a type of'accelerated ageing

'or'failure to activate the healthy ageing program.''The authors say that their'healthy age gene score'could be integrated to help decide which middle-aged subjects could be offered entry into a preventative clinical trial many years before the clinical expression of Alzheimer's.


R_www.3ders.org 2015 03152.txt.txt

The gel, similar to common hand sanitizer, minus alcohol and perfume, is able to rapidly switch from a solid to liquid state in response to stress.


R_www.3dprintingindustry.com 2015 01161.txt.txt

without corners, we have rounded edges that you can really stress. And we were able to print them in half-rings.


R_www.asianscientist.com 2015 00027.txt.txt

shift work and, perhaps, seasonal affective disorder. The study also provides a mathematical model that accurately predicts the behavior of the clock under different circumstances.


R_www.azonano.com 2015 00639.txt.txt

when releasing lithium. his expansion and contraction of aluminum particles generates great mechanical stress, which can cause electrical contacts to disconnect.


R_www.azonano.com 2015 00690.txt.txt

Many mental disorders, including depression, schizophrenia and anxiety, affect neurotransmitter systems,"said Axel Brunger, the study's principal investigator.


R_www.azosensors.com 2015 02582.txt.txt

The stress on wind turbine is recorded and then engineers can forecast its remaining service life. When a bearing is subject to a load

and the speed of sound is affected by the stress level in the material. Both these effects change the time of flight of an ultrasound wave through a bearing.


R_www.bbc.com_technology 2015 01188.txt.txt

talks to someone who has dementia? These are vital questions, and the new lab hopes that asking them in a real-life situation will improve their work.


R_www.biologynews.net_ 2015 00027.txt.txt

Fatigue and the stress of trying to plan one's life around visits to the bathroom can be debilitating.


R_www.biologynews.net_ 2015 00213.txt.txt

and the brain regions associated with dementia, and it can help contribute to a dementia diagnosis. This also provides strong evidence that dementia in humans could be called a type of'accelerated ageing

'or'failure to activate the healthy ageing program'."'"Given that early intervention is important in Alzheimer's


R_www.biologynews.net_ 2015 00221.txt.txt

or mechanical stress on the chromosomes into which our genetic material is packaged. To make sure cells stay alive


R_www.biosciencetechnology.com 2015 01776.txt.txt

extending far away from the glial cell. his has profound implications for glial disease like Krabbe, Charcot-Marie Tooth, peripheral neuropathies or Multiple sclerosis,


R_www.biosciencetechnology.com 2015 01787.txt.txt

Results of a pilot study, published in the September issue of Frontiers in Behavioral neuroscience, confirms the pathogenic role of beta amyloid in dementia as seen in both AD


R_www.biosciencetechnology.com 2015 01801.txt.txt

Alzheimer is the most common age-related dementia and the number of cases in the United states is expected to increase from the current number of about five to six million to 15 million by 2050.

Alzheimer and other dementias are projected to cost the United states $226 billion in 2015 alone, with that number rising to as high as $1. 1 trillion in 2050.


R_www.biosciencetechnology.com 2015 01822.txt.txt

Such techniques have the potential to enhance research into the origins of neurodevelopmental and neuropsychiatric disorders such as microcephaly, lissencephaly, autism and schizophrenia,


R_www.biospace.com 2015 02537.txt.txt

a drug often used to treat anxiety disorders. Researchers placed electrodes at strategic points on the skin


R_www.biotech-now.org 2015 01642.txt.txt

In addition, the council is worried that Europe G. M. O. phobia may slam the door on new technologies.


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