| Biochemistry (286) |  |
| Bioreactors (38) | |
| Biochemistry (286) | |
| Bioreactors (38) | |
including Randy Bruno (associate professor of neuroscience, Department of Neuroscience), Richard Mann (Higgins Professor of Biochemistry and Molecular Biophysics, Department of Biochemistry & Molecular Biophysics), Wesley Grueber (associate professor
"says Thomas M. Jessell, co-director of the Zuckerman Institute and Claire Tow Professor of Motor neuron Disorders, the Department of Neuroscience and the Department of Biochemistry and Molecular Biophysics at Columbia."
Tom Maniatis, Phd, the Isidore S. Edelman Professor of Biochemistry and chair of the Department of Biochemistry and Molecular Biophysics at Columbia University Medical center and director of Columbia university-wide
29-year-old Phd student Chiara Nardon, was named top young innovator in the field of biochemistry in 2013,
Bringing together biologists, chemists, microbiologists, biochemists, molecular geneticists and biotechnologists from universities, biotech firms and food and pharmaceutical multinationals from around Europe, Polymode has identified now its first eadingand ritingenzymes.
They include biomass producers advancedbiomass pre-treatment specialists catalyticand enzymatic reactions developers and finalchemical and biochemical producers and endusers.
Their newest prototype has built-in biochemical sensors, which measure such properties as the saltiness, acidity and temperature of a person's sweat, giving insight into the subject's state of health.
The biochemical engineers are now looking at integrating their prototype into A t-shirt together with other sensors,
Cancer researchers should now have a much clearer look at the complex physical and biochemical interplay involved in leaving a tumor moving through surrounding tissue and approaching a blood vessel.
but belongs to a different class of biochemical substances. Copsin is a protein whereas traditional antibiotics are often non-protein organic compounds.
It was the biochemical properties of the substance that led the scientist to do so. Copsin is an exceptionally stable protein says Essig.
Axl proteins stand like bristles on the surface of cancer cells poised to receive biochemical signals from Gas6 proteins.
The team was able to separate physical and biochemical effects on platelet behavior by forming polymer gels with different degrees of stiffness
First author Yongzhi Qiu and colleagues were also able to dissect platelet biochemistry by allowing the platelets to adhere
and then spread on the various gels under the influence of drugs that interfere with different biochemical steps.
because different biochemical pathways are involved in each step##Lam says.####Our data show that mechanosensing can occur
HSP101 may also give the proteins a biochemical kick that pushes them through the pore.
but belongs to a different class of biochemical substances. Copsin is a protein whereas traditional antibiotics are often non-protein organic compounds.
It was the biochemical properties of the substance that led the scientist to do so. opsin is an exceptionally stable proteinsays Essig.
Christoph Benning professor of biochemistry and molecular biology at Michigan State university and his colleagues unearthed the protein's potential
In the new study biogeochemists at Rice conducted side-by-side tests of the water-holding ability of three soil types#sand clay and topsoil#both with and without added biochar.
Led by bioengineering Associate professor Christina Smolke the Stanford team has spent already a decade genetically engineering yeast cells to reproduce the biochemistry of poppies with the ultimate goal of producing opium-based medicines from start to finish in fermentation vats. e are now very close to replicating the entire
Once she forges this missing link in the chain of biochemical synthesis she will have produced a bioengineered yeast that can perform all 17 steps from sugar to specific opioid drugs in a single vat. e are already working on thisshe says.
It perhaps the most important biochemical process On earth and scientists don yet fully understand how it works.
In the case of natural photosynthesis, that charge separation leads to biochemical energy, explains Jennifer Ogilvie,
of California Santa barbara as well as in the department of chemistry and biochemistry of the findings. The results of this research performed jointly with materials professor Steven Denbaars
and we are quite happy that the DNP NMR technology is so useful for understanding this plant biochemistry questionsays Hong also a faculty scientist with the US Department of energy s Ames Laboratory.
Knowing where expansin binds to cell walls ight help biochemists design more potent expansins to loosen the cell wall
Some of the bioreactors being used to cultivate the bioengineered Trichoderma fungus The bioengineered Trichoderma can be cultivated in bioreactors
The paper may have more relevance for our understanding of biogeochemical cycles internal to the oceans.
large field-of-view and implantable features will allow researchers to use this in fields ranging from biochemistry to mining. b
Researchers in Sweden have revealed a surprising change in brain biochemistry that occurs during the training of working memory,
"Many findings of altered brain biochemistry may simply reflect the patients'inattentiveness, he says. Klingberg says that his team's results may also have practical implications for training working memory.
Shining a light on the cells triggers a cascade of biochemical reactions that transfer electrons along a chain of molecules#and switches the transistor on.
Other researchers are trying to repurpose the biochemistry of green algae to make biofuels, and Saraf thinks that his device could monitor how efficiently the new strains photosynthesize.
and responds just like native tissue to external stimuli such as electrical pulses, biochemical signals and pharmaceuticals.
and also to reproduce the functional and biochemical signals of diseasesspecially rare ones and those that make taking muscle biopsies difficult.
by removing a biochemical lampthat prevents connections between nerve cells in the brain from growing stronger.
said Tom Maniatis, Phd, the Isidore S. Edelman Professor, chair of biochemistry and molecular biophysics,
senior researcher at the Department of Medical Biochemistry and Biophysics. ut in recent years wee developed much more sensitive methods of analysis that allow us to see which genes are active in individual cells.
The study was carried out by Sten Linnarsson and Jens Hjerling-Leffler research groups at the department of medical biochemistry and biophysics, in particular by Amit Zeisel and Ana Muños Manchado.
and quantifying the biochemical effects of therapeutic interventions, said Anders M. Dale, Phd, professor of neurosciences and radiology and director of the Center for Translational Imaging and Precision Medicine at UC San diego and the study senior author e
According to the press release, uscle progenitors were injected directly into the matrix sheaths that define the position of each muscle. he leg was left to culture in a bioreactor for five days.
After two weeks, the scientists removed the leg from the bioreactor to analyze it. Tests confirmed the presence of vascular cells along blood vessel walls
says Helen Zgurskaya, a biochemist at the University of Oklahoma, Norman, who studies how bacteria become susceptible to antibiotics. his study demonstrates that unculturable bacteria have unrecognized new,
and obtain real-time biochemical information about disease sites and also healthy tissues which is not always straightforward.
They also found that these changes did not affect the biochemical pathway used by the yeast to produce ethanol:
It s based on a naturally occurring biomarker that does not require any biochemical processing of samples says Han one of the senior authors of a paper describing the technique in the Aug 31 issue of Nature Medicine.
Because researchers cannot study the biochemistry of the living human brain the genes that predispose people to schizophrenia
and animal models that more faithfully match both the genetic variation and the biochemical processes seen in human patients.
Kelley a professor of biochemistry and pharmaceutical sciences at the University of Toronto. Lead authors are Simon Wisnovsky who received his Phd from the University of Toronto and MIT alumnus Justin Wilson Phd 13.
The technology could also be useful for predicting recurrence of clots says Henri Spronk an assistant professor of biochemistry at Maastricht University in The netherlands.
With surfaces functionalized with the same biochemical motifs found in their human counterparts these PLNS also can summon other platelets to the site
Assistant professor Amir Karton from UWA's School of Chemistry and Biochemistry said the finding published this week in Chemical Physics Letters journal was significant
Moreover the solution came straight from the life sciences biochemistry in fact. The technique known as density gradient ultracentrifugation is a decades-old process used to separate biomolecules.
Paul Weiss distinguished professor of chemistry and biochemistry and a member of UCLA's California Nanosystems Institute developed the method for producing the nanoribbons with Patrick Han and Taro Hitosugi professors at the Advanced Institute
and observe them at work is every biochemist's dream. This would enable the scientists to research in detail
and Biochemistry and Molecular biology at Penn State. In a paper first published online on Sept. 9 in the journal Nature Chemistry, Mallouk and colleagues at Penn State and the Research center for Exotic Nanocarbons at Shinshu University, Japan, describe a method called intercalation,
a UCLA professor of chemistry and biochemistry who led the research. Electrochemical capacitors, also known as ECS or supercapacitors, are an important technology for the future of energy storage and mobile power supplies,
and nanometer scale is crucial from semiconductor electronics to biochemistry and medicine. Explore further: High-resolution microscopy technique resolves individual carbon nanotubes under ambient condition c
in collaboration with colleagues at the University of Michigan, have developed a 3-D artificial enzyme cascade that mimics an important biochemical pathway that could prove important for future biomedical and energy applications.
and Biochemistry and directs the Center for Molecular Design and Biomimicry at the Biodesign Institute.
to another enzyme to carry out the next step in a biochemical pathway in the human body. For the new study, the researchers chose a pair of universal enzymes, glucose 6-phosphate phosphate dehydrogenase (G6pdh) and malate dehydrogenase (MDH),
"said Walter. The work also opens a bright future where biochemical pathways can be replicated outside the cell to develop biomedical applications such as detection methods for diagnostic platforms."
Research by Jeremy Duczynski from the University of WA's School of Chemistry and Biochemistry investigated
It's possible enhancing the biochemical events that lead to growth in the brain would cause issues elsewhere in the body like potentially raising the risk of cancer.
The regrowth of the arm takes place inside a bioreactor providing nutrients and stimulation for the limb to reform.
says the paper provides a novel mechanistic link between chronic inflammation and cancer development. ith a combination of biochemical,
and involved the collaboration of chemists, cancer biologists, computer modeling experts, biochemists and biophysicists at KUOTABLY the labs of Xu, Jeffrey Aubé in the Department of Medicinal Chemistry and Jon Tunge in the Department of chemistry.
In a research paper published in the Journal of Cell biology, Alessandro Vindigni, Ph d.,professor in the Edward A. Doisy Department of Biochemistry and Molecular biology at Saint louis University
The experiment seeks to understand how the effects how physical forces such as gravity affect the biochemistry of bone cells
says the paper provides a novel mechanistic link between chronic inflammation and cancer development. ith a combination of biochemical,
Foldit, a research project out of the University of Washington Center for Game Science in collaboration with the UW Department of Biochemistry,
and a variety of biochemical building blocks. It is a major advance towards synthetic photosynthesis, a type of solar power based on the ability of plants to transform sunlight,
"said Thomas moore, a professor of chemistry and biochemistry at Arizona State university. Ultimately, researchers hope to create an entirely synthetic system that is more robust and efficient than its natural counterpart.
The research team developed a bioreactor using a viscous fluid made partly of substances found in the walls of mushrooms
The multidisciplinary team was able to 3d print custom silicone guides infused with biochemical cues that proved to effectively regrow nerve tissue in lab rats.
Usually, the rate of a biochemical reaction increases as the temperature rises, so in this case the speed of the body clock should increase
most efforts to image highly localized biochemical conditions such as abnormal ph *and ion concentration--critical markers for many disorders--rely on various nanosensors that are probed using light at optical frequencies.
One of the most significant features of GEMS is that they can be tuned"in fabrication to respond to different biochemical states
or diagnose substances at a molecular level. ur system can do chemistry, biology, biochemistry, molecular biology, clinical diagnosis,
Chen started out as a biochemist working on biomedical devices. After he joined Berkeley Lab around 2000, he learned about quantum dots,
and a variety of biochemical building blocks. The research is a major advance toward synthetic photosynthesis, a type of solar power based on the ability of plants to transform sunlight, carbon dioxide and water into sugars.
Moore is a professor of chemistry and biochemistry at Arizona State university, where he previously headed the Center for Bioenergy & Photosynthesis. Ultimately,
Thus proteins that bind specifically to complementary chemical structures are also indispensable for many biochemical and biotechnological applications.
#eyond revolutionary bioreactor-in-a-briefcase brings warzone production The project, sponsored by a coalition including Thermo Fisher, Pfizer,
and streptokinase cross three bioreactors. One-and-a-half hours and youe done. igarette pack reactorsrao team has created 3d printed designs for their next goal:
flat-chip bioreactors the size of cigarette packs for continuous processing. The scientists are also working on making purification portable.
#eyond revolutionary bioreactor-in-a-briefcase brings warzone production The project, sponsored by a coalition including Thermo Fisher, Pfizer,
and streptokinase cross three bioreactors. One-and-a-half hours and youe done. Cigarette pack reactors Rao team has created 3d printed designs for their next goal:
flat-chip bioreactors the size of cigarette packs for continuous processing. The scientists are also working on making purification portable.
and Lora S. Lurie Professor in Medicine-Hematology/Oncology and Biochemistry and Molecular genetics, and a member of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
In addition to the direct medical implications, the new study also shifts a fundamental principle of biochemistry known as allostery.
and structure of phosphoproteins and identify which ones are involved in disease. his innovation will help advance the understanding of human biochemistry and physiology,
a biochemical engineer who led the Northwestern team. The study was published Sept. 9 by the journal Nature Communications.
explained M. Laura Feltri, M d.,senior author on the paper and an HJKRI researcher and professor of biochemistry and neurology in the Jacobs School of medicine and Biomedical sciences at UB. o study myelin,
and the biochemistry communities, said Quiroz. heyl be able to push the limits of what we know about these kinds of materials
#Real-time Data For Cancer Therapy, MIT Study Biochemical sensor implanted at initial biopsy could allow doctors to better monitor
Now, researchers at MIT Koch Institute for Integrative Cancer Research are closing that information gap by developing a tiny biochemical sensor that can be implanted in cancerous tissue during the initial biopsy.
about one-third of the world supply has shifted to bioreactors. his is complicated the most chemical synthesis ever engineered in yeast,
with proper controls against abuse, allow bioreactors to be located where they are needed, she said. In addition to bioengineering yeast to convert sugar into hydrocodone,
explains Christian Kastrup, an assistant professor in the Department of Biochemistry and Molecular biology and the Michael Smith Laboratories at the University of British columbia.
biochemical engineers and emergency physicians to develop simple, gas-generating calcium carbonate micro-particles that can be applied in powder form to stop critical bleeding.
and that is why we are using bioreactors which then provides controlled and sterile environment for copsin production."
"Biochemistry professor Kevin Plaxco of the University of California at Santa barbara, who supervised Vallée-Belisle's previous postdoctoral work and who is himself an expert in electrochemical methods to detect antibodies,
which plants use solar energy to reduce carbon dioxide to acetate, a ubiquitous biochemical uilding block. In the second step, acetate is converted to more complex chemical precursors.
and biochemical building blocks it needs to grow during the first 11 weeks of pregnancy. During this time the embryo is too small and delicate for the umbilical cord to be attached
which produces biochemical signals suitable for transmission to neurons. In the tests pressure signals from the skin generated light pulses that activated a line of light-sensitive nerve cells.
"It all started with an intuition we published in the journal Biochemistry in 2012, "explains Gabriele Giachin, first author of the study and former SISSA Phd student (today at the European Synchrotron radiation Facility, ESRF, in Grenoble, France)."
about one third of the world supply has shifted to bioreactors. The artemisinin experiments proved that yeast biosynthesis was involved possible,
with proper controls against abuse, allow bioreactors to be located where they are needed, she says. In addition to bioengineering yeast to convert sugar into hydrocodone,
"said Hannele Ruohola-Baker, Ph d.,University of Washington professor of biochemistry and senior author of the paper."
"said Dmitri Kudryashov, Ph d.,assistant professor of chemistry and biochemistry at OSU and senior author of the study."
"Therefore, ACD effectively hijacks formin by converting actin molecules into new potent poisons,"said co-corresponding author Elena Kudryashova, Ph d.,a research scientist in chemistry and biochemistry at OSU.
"said first author David Heisler, a graduate student in the Ohio State Biochemistry Program.""This establishes an entirely new toxicity mechanism. e
"explained senior author Shohei Koide, Ph d.,professor of biochemistry and molecular biophysics at the Chicago."
"explained senior author M. Laura Feltri, M d.,professor of biochemistry and neurology in the Jacobs School of medicine and Biomedical sciences at UB."
offering the possibility of directly testing potential avenues for therapy on the patient's own tissues. ur work, the Development article concluded, rovides a unique platform to produce human cones for developmental, biochemical,
"Scientists have spent decades trying to find biochemical similarities between placenta tissue and cancer, but we just didn't have the technology to find it,"noted project leader Mads Daugaard, Ph d.,assistant professor of urologic science at UBC and a senior research scientist at the Vancouver Prostate Centre, part of the Vancouver Coastal
"The researchers came up with a biochemical processing method that allows them to generate very large DNA molecules with many thousands of nucleotides.
Replete with a range of biochemical"cues"designed to enhance and nurture nerve cell formation, these devices have been tested successfully in the bodies of living rats in a laboratory.
These 3d-printed nerve pathways were embedded with biochemical cues to promote growth. The final 3d-printed product was implanted then into rats with severed nerves.
But the discovery could help provide new understandings of the way that the biochemistry of the brain and body works, in the meantime e
Biochemical engineer Christina Smolke and colleagues had been working on the problem of synthesizing opioids and other plant-based medicines in the lab for about a decade.
They do incredible and beautiful biochemistry, "she said.""But they do it in a way that's inefficient.
of which are unknown and likely unrelated to optimized production in large-volume bioreactors, would need to be addressed for engineered yeast to ever realize home-brew biosynthesis of medicinal opiates at meaningful yields."
called a bioreactor, which simulates conditions found inside the Body temperature, humidity, acidity and nutrient composition all need to be just right for the stem cells to transform into bone-growing cells called osteoblasts,
a biochemist at the Baylor College of Medicine in Houston, said in a statement. To make sure that this supercoiled DNA actually shows up in the body,
PR biosensing is a valuable tool to investigate a wide range of biochemical reactions estimate their chemical kinetics and other characteristics.
The animal uses a biochemical cascade to change the thickness of the layers and their spacing.
"Professors Ray and Paul Dupree have discussed the possibility of working together to solve outstanding questions in plant biochemistry for twenty years.
including investigating individual biochemical reactions and detecting molecules such as contaminants or explosives at extremely low concentrations.
"Amongst other things, this information can help to predict how the molecules might interact with biochemical processes in living cells,
such as in biochemical analysis,"said Dr Cortes. The discovery opens up the possibility for new equipment that can track individual biochemical reactions in over a period of time,
which cells convert mechanical stimuli into biochemical activity. These factors include cytoskeletal structure, adhesion dynamics and intracellular tension,
and 3d printing techniques to create a custom silicone guide implanted with biochemical cues to help nerve regeneration.
and the biochemistry communities,"said Quiroz.""They'll be able to push the limits of what we know about these kinds of materials
"SPR biosensing is a valuable tool to investigate a wide range of biochemical reactions, estimate their chemical kinetics and other characteristics.
Structural Biochemistry) at Forschungszentrum Jülich in Germany. The results were published in Nature Communications. X-ray crystallography is the most prolific method for determining protein structures.
and work are based on biochemical and genetic studies, "Li said, likening the situation to the famous parable of the three blind men trying to describe an elephant,
O'Donnell's group had published previously biochemical results related to this work.""DNA replication is one of the most fundamental processes of life,
so it is every biochemist's dream to see what a replisome looks like, "Sun said."
while he was a professor in UD's Department of chemistry and Biochemistry, and Darrin Pochan, professor and chair of UD's Department of Materials science and engineering.
says the paper provides a novel mechanistic link between chronic inflammation and cancer development. ith a combination of biochemical, genetic,
The study, led by Muniswamy Madesh, Phd, Associate professor in the Department of Biochemistry, the Cardiovascular Research center,
and sophisticated EEG, sleep and biochemical studies are performed. This includes the sequencing of their entire genome.
and the bottom layer acts as the circuit to transport electrical signals and translate them into biochemical stimuli compatible with nerve cells.
"Scientists have spent decades trying to find biochemical similarities between placenta tissue and cancer, but we just didn't have the technology to find it,
where the work was done with biochemist Yingfu Li and graduate student Carmen Carrasquilla.""Imagine being able to clearly identify contaminated meat, vegetables or fruit.
and involved the collaboration of chemists, cancer biologists, computer modeling experts, biochemists and biophysicists at KU--notably the labs of Xu, Jeffrey Aub in the Department of Medicinal Chemistry and Jon Tunge in the Department of chemistry.
Every once in a while, however, a pro-growth-hormone molecule docks at a receptor on the surface, setting off a cascade of biochemical events inside the cell."
But biochemical experiments and clinical trials have shown that KP1212 induces mutations by pairing with adenine.
a Curators Professor of Animal Science and a professor of biochemistry, and his colleagues, says these new stem cells can help advance research on preeclampsia and a number of other areas of the human reproductive process."
They also added two other drugs that temporarily inhibited key biochemical pathways associated with the pluripotent state of the stem cells.
who led the research from the Centre for Biochemical Pharmacology, based within Queen Mary University of London William Harvey Research Institute,
which are problematic for conventional gel electrophoresis, a frequently used technique in biochemistry and molecular biology to size DNA and RNA fragments.
and do not efficiently activate the biochemical cascade of events that ultimately lead to DNA repair.
because you are directly targeting the underlying biochemical defect in obesity, "Durante said.""L-arginine is a natural amino acid commonly found in red meat, poultry, fish and dairy products.
Their in-vitro experiments uncovered a multi-stage biochemical process in which protein molecules are dissolved from the aggregates.
the Phd in biochemistry and molecular biology Gabriel Cabrera Betanzos designed a microencapsulation process from pomegranate juice
professor of biochemistry and molecular biophysics, was able to change the specificity of an enzyme,
An international team of researchers led by Christian Haass (Professor of Metabolic Biochemistry at LMU and Speaker for the German Center for Neurodegenerative Diseases in Munich) and Dr. Michael Willem (LMU) has made now a discovery
followed by thorough clinical, biochemical and molecular biological investigations, the researchers found the causative mutation
, it can catalyze biochemical reactions. The research group developed the molecular biology method MIME (Mutational Interference Mapping Experiment) to investigate the interaction of RNA with its respective interaction partners in detail.
said biochemist Pia D. Vogel, lead author on the scientific paper reporting the discovery. So far there's no approved drug on the market that reverses cancer chemotherapy resistance caused by P-glycoprotein
or P-gp for short, said Vogel, a biochemistry professor at SMU. One potential drug, Tariquidar, is currently in clinical trials,
and found four that inhibited the biochemical function of P-gp, stopping it in its action.
said biochemist Pia D. Vogel, lead author on the scientific paper reporting the discovery. So far there's no approved drug on the market that reverses cancer chemotherapy resistance caused by P-glycoprotein
or P-gp for short, said Vogel, a biochemistry professor at SMU. One potential drug, Tariquidar, is currently in clinical trials,
and found four that inhibited the biochemical function of P-gp, stopping it in its action.
and a variety of biochemical building blocks. The research is a major advance toward synthetic photosynthesis, a type of solar power based on the ability of plants to transform sunlight, carbon dioxide and water into sugars.
Moore is a professor of chemistry and biochemistry at Arizona State university, where he previously headed the Center for Bioenergy & Photosynthesis. Ultimately,
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