Biotechnology

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Synopsis: Biotech: Biotechnology:

advance manufacturing and biotechnology. e started with ICT because it the easiest thing to start.

"It's an interesting way that Bluetooth can interact with the biotech industry.##Other personal health sensors that use Bluetooth include the Cardiopad,

especially by using emerging biotechnologies, and might encourage diversity in the kinds of architectures we produce.

This promising compound will soon join the regulatory pipeline of a biotech company called Rxbio Inc,

#Biogen idec Columbia to Conduct Collaborative Genetics Research Biogen idec and Columbia University Medical center have formed a $30 million strategic alliance to conduct genetics discovery research on the underlying causes of disease

The agreement will integrate genomics research conducted at Columbia with Biogen idec understanding of disease mechanisms and pathways,

Biogen idec. e are committed to working with leading institutions such as Columbia to advance basic genetic research and,

The collaboration will enable Biogen idec and Columbia to investigate the genomes of patients showing unusual treatment responses

a leading developmental biologist with Montana State university, told Bioscience Technology. Pera was uninvolved in the research.""The paper uncovers fundamentals in producing the earliest stage germ cells.

told Bioscience Technology. think this is a major leap forward.""Built on Kyoto University research The work is built on research done by the Kyoto University lab of stem cell researcher Mitinori Saitou.

Hanna told Bioscience Technology. or example, H3k27me3, a repressive chromatin mark, is depleted over developmental regulators in naive conditions.

Hanna concluded to Bioscience Technology. was not surprised in a way. I was confident that the failure with conventional ipscs would be resolved by toggling them back towards an alternative more naive state.

The helmet is fitted with unique biosensors that measure physiological life signs. Monitoring the pilot heartbeat, blood flow and oxygen level in the blood stream.

biotechnology and information technologies to develop an artificial hand that patients were able to experience, to some degree,

#An innovative production platform for micro-products Micro-products have become increasingly important in the medical, biotechnology, consumer and automotive sectors.

We believe that the PEF will become the new world standard for polyester bottles. with the possibilities it opens up for future work in vaccine discovery was recognised with the naming of Professor Lomonossoff as Innovator of the Year 2012 by the Biotechnology and Biological sciences Research Council

was recognised with the naming of Professor Lomonossoff as Innovator of the Year 2012 by the Biotechnology and Biological sciences Research Council (BBSRC), U s

Bringing together biologists, chemists, microbiologists, biochemists, molecular geneticists and biotechnologists from universities, biotech firms and food and pharmaceutical multinationals from around Europe, Polymode has identified now its first eadingand ritingenzymes.

but also for public health budgets and for the European biotechnology industry n

#0. 05mm: a new accuracy standard for industrial robots An EU-funded project brought together industry

#PHARMA-PLANTA#Harnessing plant biotechnology to revolutionise pharmaceutical production The hope is that the drug will prove effective in preventing HIV infection.

"Discovered by one of the four private commercial partners in the project, Austrian biotech company Polymun,

the success of PHARMA-PLANTA"is a springboard for European plant biotechnology and will enable many important medical products to be realised".

"Indeed, the videogame identifies boredom, excitement or anxiety in patients-and their cognitive responses-with the help of emotion recognition technologies and biosensors.

The National institutes of health and the Mathematical Biosciences Institute of the National Science Foundation supported the work.

##Leveraging expertise in optical biosensors and hemorrhagic fever diseases our collaborative research effort has produced a highly sensitive device with the potential to perform rapid diagnostics in clinical settings.##

In the controllable biosensor developed by doctoral candidate Nicolas Lapique the gene responsible for the output signal is not active in its basic state as it is installed in the wrong orientation in the circuit DNA.

The National institutes of health the Rice Century Scholars Program and a Hamill Innovation Award by the Rice university Institute of Biosciences and Bioengineering supported the research.

Giaccia and Cochran are scientific advisors to Ruga Corp. a biotech startup in Palo alto that has licensed this technology from Stanford.

The group includes researchers at the Icahn School of medicine at Mount sinai Washington University the University of Texas Southwestern Medical center Howard University and Microbiotix Inc. a Massachussetts biopharmaceutical company Source:

and Molecular Biosciences. e have discovered genes that make up the cell wall of the strep bacteria, which is composed mainly of the group A carbohydrate or GAC,

and may be suited better for a biotech company, he says. e focus more on the performance of the hydrogels and the underlying molecular mechanisms The National institutes of health,

says Robert Krug, professor of molecular biosciences at University of Texas at Austin. In addition to countering the body defense mechanisms,

In the controllable biosensor developed by doctoral candidate Nicolas Lapique the gene responsible for the output signal is not active in its basic state as it is installed in the wrong orientation in the circuit DNA.

and the Institute for Collaborative Biotechnologies supported the work. Source: Caltechyou are free to share this article under the Creative Commons Attribution-Noderivs 3. 0 Unported license t

The Division of Chemical sciences Geosciences and Biosciences of the Office of Basic energy Sciences of the US Department of energy supported the work.

and the Army Research Office through the Institute for Collaborative Biotechnologies at Caltech supported the research.

or female says Peter Koopman a professor from the University of Queensland s Institute for Molecular Bioscience. ost mammals including humans

Their results are published in the journal Nature Biotechnology. One billion acres#When Bt crops were introduced first the main question was how quickly would pests adapt

and will be run by Arthur Levinson, chairman and ex-CEO of biotech company Genentech. Google gave exclusive access to Time magazine for a story on the new venture.

With some longer term, moonshot thinking around healthcare and biotechnology, I believe we can improve millions of lives.

That s exactly what#Sanaria, a biotechnology founded in 2003 by long-time malaria researcher Stephen Hoffman and based in a suburb of Washington,

Includes the broad redefinition and expansion of biotechnology, with the ultimate goals of being able to design,

like a living cockroach, says Ángel Goñi Moreno of the National Center for Biotechnology in Madrid,

allows Medifocus to partner up with other biotech companies in helping to develop and commercialize targeted thermoactivated/released drugs and gene products which,

An expert on sustainable agriculture and the potential environmental risks of biotechnology Mellon holds a doctorate in molecular biology and a law degree.

Only this year did agricultural biotech company Monsanto introduce its first drought tolerant seed variety Droughtgard. According to the Monsanto website the variety has produced a five-bushel

and biofuels and the ability to create custom-made yeast would provide useful too for the biotech industry.

the Wellcome Trust has joined forces with the Indian government's Department of Biotechnology to fund postdoctoral researchers in the country through a new,

For example, Riley has been collaborating with Sangamo Biosciences, a biotechnology company based in Richmond, California, to determine whether the company's technique for snipping out targeted genes could be used to delete the CCR5 gene.

Sangamo announced last week that it has launched a Phase I clinical trial that will involve removing a sample of the participant's T cells,

They will be awarded every two years starting in 2014, to global leaders in the fields of sustainable development, biopharmaceutical science, Chinese studies and the rule of law.

October 2010 Biotechnology company Geron doses first patient in world s first clinical trial to test an ES-cell product.

Former heads of the biotech company Geron, based in Menlo Park, California, last week announced an agreement to acquire stem-cell assets including the company s flagship human ES-cell trial, in

It was in August 2009, that Sherley and Theresa Deisher, the chief executive of AVM Biotechnology in Seattle,

Lu says that the approach could also be useful in biotechnology. Using simple forms of these addressable switches,

as well as the launch of several SMALL CAR-focused biotechnology firms. And Sadelein says that he is an investigator on a trial with the Dana-Farber Cancer Institute in Boston

"It s a huge unmet need, says David Ferreiro, a biotechnology analyst with investment bank Oppenheimer & Company in New york,

Personalis, down the road in Menlo Park, offers sequencing services and interpretation for clinicians and pharmaceutical and biotechnology companies.

The study, conducted by an international ALS consortium that includes scientists and clinicians from Columbia University Medical center (CUMC), Biogen idec,

and Hudsonalpha Institute for Biotechnology, was published today in the online edition of Science. he identification of TBK1 is exciting for understanding ALS pathogenesis,

and Tim Harris, Phd, DSC, Senior vice president, Technology and Translational Sciences, Biogen idec. hese findings demonstrate the power of exome sequencing in the search for rare variants that predispose individuals to disease and in identifying potential

but this is a perfect example of a large, complex project that required many parts, with equal contributions from Biogen idec.

including bladder cancer. rology hasn gotten really the benefit of improvement in the biotech revolution. This type of technology can revolutionize how we do drug therapy in urology,

Indeed, collecting clinical data is a major challenge in spinning biotechnology out of the lab, notes Cima,

The new method produces the combination of desired properties in as small a package as possible Bawendi says which could help pave the way for particles with other useful properties such as the ability to bind with a specific type of bioreceptor or another

Biologics is the fastest growing field in biotech because it gives you the ability to do highly predictive designs with unique targeting capabilities says senior author Mehmet Fatih Yanik an associate professor of electrical engineering and computer science and biological engineering.

and electrical engineering and computer science the researchers described their findings in the Sept. 21 issue of Nature Biotechnology.

In the new Nature Biotechnology study graduate students Robert Citorik and Mark Mimee worked with Lu to target specific genes that allow bacteria to survive antibiotic treatment.

which have numerous applications in a variety of fields including biotechnology. He adds This work cleverly combines low-hysteresis droplet movement with low-magnetic-field-driven droplet propulsion to achieve impressive capabilities.

The company which aims to leverage biotechnology as a way to solve environmental issues is also modifying their system to generate value from wastewater in agricultural and military fields,

We are leveraging biotechnology to provide the highest return on investment for managing water. To that end, Cambrian is working on other projects that leverage exoelectrogenic microbes to treat wastewater.

Meeting at MIT in 2006 over a shared fondness for biotech, Silver, then a research scientist in MIT Space Systems Lab,

is to leverage biotechnology to advance a sustainable ndustrial ecology, where the waste of industry is recycled to create energy

The findings described in the March 30 issue of Nature Biotechnology offer the first evidence that this gene-editing technique known as CRISPR can reverse disease symptoms in living animals.

and one of the lead authors of the Nature Biotechnology paper. This work shows that CRISPR can be used successfully in adults

as well as serve as plant-based biosensors and stress reducers. By adapting the sensors to different targets,

and the Institute for Collaborative Biotechnologies through the U s army Research Office u

#Resistance is futile Cisplatin is given a chemotherapy drug to more than half of all cancer patients. The drug kills cells very effectively by damaging nuclear DNA but if tumors become resistant to cisplatin they often grow back.

In the previous version of the system reported last December in Nature Biotechnology the researchers used mass spectrometry to distinguish the fragments by their mass.

Now, Semprus Biosciences, a startup co-founded by two MIT alumni Christopher Loose Phd 7

the biomaterial has positioned Semprus as a fast-growing biotech firm in Kendall Square. In its six years, the startup seed-funded, in part,

The new technology is described in a paper appearing in the journal Nature Biotechnology, written by MIT Polina Anikeeva and 10 others.

Earlier this month, MIT spinout Microchips Biotech partnered with a pharmaceutical giant to commercialize its wirelessly controlled, implantable,

Invented by Microchips Biotech cofounders Michael Cima, the David H. Koch Professor of Engineering, and Robert Langer, the David H. Koch Institute Professor, the microchips consist of hundreds of pinhead-sized reservoirs,

and osteoporosis. Now Microchips Biotech will begin co-developing microchips with Teva Pharmaceutical, the world largest producer of generic drugs,

Microchips Biotech says these microchips could also improve medication-prescription adherence a surprisingly costly issue in the United states. A 2012 report published in the Annals of Internal medicine estimated that Americans who don stick to prescriptions rack up $100 billion to $289 billion

Microchips Biotech will continue work on its flagship product, a birth-control microchip, backed by the Bill and Melinda Gates Foundation,

Cima, who now serves on the Microchips Biotech board of directors with Langer, sees this hormone-releasing microchip as one of the first implantable rtificial organsecause it acts as a gland. lot of the therapies are trying to chemically trick the endocrine systems Cima says. e are doing that with this artificial organ we created. ild ideasinspiration for the microchips came in the late 1990s,

For years, the technology underwent rigorous research and development at Microchips Biotech. But in 2011, Langer and Cima,

EMS innovationsmicrochips Biotech made several innovations in the microelectromechanical systems (MEMS) manufacturing process to ensure the microchips could be commercialized.

To do so, Microchips Biotech modified a cold-welding ongue and grooveprocess. This meant depositing a soft,

"We have developed a smart SERS biosensor for the rapid screening of bladder cancer, "says Olivo."

A new study shows that this feature could facilitate easier nanoscale manufacturing of biosensors and plasmonic devices with intricate high-density surface structures.

The research team received funding for their study from the Israel Ministry of Science and Technology the European Research Council and the Biotechnology and Biological sciences Research Council.

And of course any biosensor needs to be accurate. You need to know the numbers. Is it 100%accurate?

In their latest paper, researchers from Cardiff University's Schools of Biosciences and Physics showed that non-fluorescing nanodiamonds (diamonds without defects) can be imaged optically

Professor Paola Borri from the School of Biosciences, who led the study, said:""This new imaging modality opens the exciting prospect of following complex cellular trafficking pathways quantitatively with important applications in drug delivery.

#New absorber will lead to better biosensors Biological sensors or biosensors are like technological canaries in the coalmine.

By converting a biological response into an optical or electrical signal they can alert us to dangers in our external and internal environments.

An optical biosensor works by absorbing a specific bandwidth of light and shifting the spectrum

The narrower the band of absorbed light is the more sensitive the biosensor. Currently plasmonic absorbers used in biosensors have a resonant bandwidth of 50 nanometers said Koray Aydin assistant professor of electrical engineering and computer science at Northwestern University's Mccormick School of engineering and Applied science.

It is significantly challenging to design absorbers with narrower bandwidths. Aydin and his team have created a new nanostructure that absorbs a very narrow spectrum of light#having a bandwidth of just 12 nanometers.

This ultranarrow band absorber can be used for a variety of applications including better biosensors. We believe that our unique narrowband absorber design will enhance the sensitivity of biosensors Aydin said.

It's been a challenge to sense very small particles or very low concentrations of a substance.

Dr. Tal Dvir and his graduate student Michal Shevach of TAU's Department of Biotechnology, Department of Materials science and engineering,

Their optical biosensor for single unlabelled molecules could also be a breakthrough in the development of biochips:

and Biosensors at the Max Planck Institute for the Science of Light has succeeded now in amplifying the interaction of light with DNA molecules to the extent that their photonic biosensor can be used to observe single unlabelled molecules and their interactions.

"The researchers have tested their optical biosensor with a sample containing both an exactly matching DNA fragment

#Graphene sensor tracks down cancer biomarkers An ultrasensitive biosensor made from the wonder material graphene has been used to detect molecules that indicate an increased risk of developing cancer.

The biosensor has been shown to be more than five times more sensitive than bioassay tests currently in use and was able to provide results in a matter of minutes opening up the possibility of a rapid point-of-care diagnostic tool for patients.

The biosensor has been presented today 19 september in IOP Publishing's journal 2d Materials. To develop a viable bionsensor the researchers from the University of Swansea had to create patterned graphene devices using a large substrate area

and low pressure to form the basis of the biosensor. The researchers then patterned graphene devices using semiconductor processing techniques before attaching a number of bioreceptor molecules to the graphene devices.

These receptors were able to bind to or target a specific molecule present in blood saliva or urine.

In their study the researchers used x-ray photoelectron spectroscopy and Raman spectroscopy to confirm that the bioreceptor molecules had attached to the graphene biosensor once fabricated

and then exposed the biosensor to a range of concentrations of 8-OHDG. When 8-OHDG attached to the bioreceptor molecules on the sensor there was a notable difference in the graphene channel resistance

which the researchers were able to record. Results showed that the graphene sensor was capable of detecting 8-OHDG concentrations as low as 0. 1 ng ml-1

The graphene biosensor was also considerably faster at detecting the target molecules completing the analysis in a matter of minutes.

Moving forward the researchers highlight the potential of the biosensor to diagnose and monitor a whole range of diseases as it is quite simple to substitute the specific receptor molecules on the graphene surface.

which make it an ideal material for fabricating biosensors. Now that we've created the first proof-of-concept biosensor using epitaxial graphene we will look to investigate a range of different biomarkers associated with different diseases and conditions as well as detecting a number of different biomarkers on the same chip.

Explore further: On the edge of graphene More information: Generic epitaxial graphene biosensors of ultrasensitive detection of cancer risk biomarker Z Tehrani et al 2014 2d Mater. 1 025004. iopscience. iop. org/2053

-1583/1/2/025004/articl l

#Startup scales up graphene production develops biosensors and supercapacitors An official of a materials technology and manufacturing startup based on a Purdue University innovation says his company is addressing the challenge of scaling graphene production for commercial applications.

Glenn Johnson CEO of Bluevine Graphene Industries Inc. said many of the methodologies being utilized to produce graphene today are not easily scalable

biosensors and supercapacitors. Johnson said the company's first-generation glucose monitoring technology could impact the use of traditional testing systems like lancets

We also are focused on working with potential customers to continue to develop baseline products for both our biosensor

#Team develops ultra sensitive biosensor from molybdenite semiconductor Move over graphene. An atomically thin two-dimensional ultrasensitive semiconductor material for biosensing developed by researchers at UC Santa barbara promises to push the boundaries of biosensing technology in many fields from health care to environmental protection to forensic industries.

Based on molybdenum disulfide or molybdenite (Mos2) the biosensor materialsed commonly as a dry lubricanturpasses graphene's already high sensitivity offers better scalability

and low-cost biosensors that can eventually allow single-molecule detectionhe holy grail of diagnostics and bioengineering research said Samir Mitragotri co-author and professor of chemical engineering and director of the Center for Bioengineering at UCSB.

While graphene has attracted wide interest as a biosensor due to its two-dimensional nature that allows excellent electrostatic control of the transistor channel by the gate

and high surface-to-volume ratio the sensitivity of a graphene field-effect transistor (FET) biosensor is restricted fundamentally by the zero band gap of graphene that results in increased leakage current leading to reduced sensitivity

Monolayer or few-layer Mos2 have a key advantage over graphene for designing an FET biosensor:

and increases the abruptness of the turn-on behavior of the FETS thereby increasing the sensitivity of the biosensor said Banerjee.

Moreover the channel length of Mos2 FET biosensor can be scaled down to the dimensions similar to those of small biomolecules such as DNA

The Mos2 biosensors demonstrated by the UCSB team have provided already ultrasensitive and specific protein sensing with a sensitivity of 196 even at 100 femtomolar (a billionth of a millionth of a mole) concentrations.

Biosensors based on conventional FETS have been gaining momentum as a viable technology for the medical forensic

Such biosensors allow for scalability and label-free detection of biomoleculesemoving the step and expense of labeling target molecules with florescent dye.

and low-cost ultrasensitive biosensors continued Kis who is connected not to the project. Explore further: New rapid synthesis developed for bilayer graphene and high-performance transistors More information:

Researchers from the Institut Català de Nanociència i Nanotecnologia's (ICN2 Catalan Institute of Nanoscience and Nanotechnology) Nanobioelectronics and Biosensors Group led by the ICREA Research Prof Arben Merkoçi work

#Designing ultra-sensitive biosensors for early personalised diagnostics A new type of high-sensitivity and low-cost sensors,

called plasmonic biosensors, could ultimately become a key asset in personalised medicine by helping to diagnose diseases at an early stage.

In biosensors, protein molecules are identified by irradiating them with infrared light and by analysing the spectrum of the light they emit, known as a Raman spectrum.

To do so, the researchers attached bioreceptors, fragments of DNA engineered to recognise specific proteins, to the nanoantennas.

When the nanoantennas studded with the bioreceptors are incubated in a solution that contains the biomarkers to be detected,

they show the Raman fingerprints of both the bioreceptor and the biomarker, as Gucciardi points out.

who has been developing plasmonic biosensors at the University of Victoria, British columbia, Canada. He also believes that such approach will make medical care more cost effective."

The"end-users"of these biosensors have to understand that the development of these devices by researchers in many disciplines is a long process, notes Estévez.

She adds that these biosensors will need to be integrated with optical components, with electronics for reading out the measurements, software to process all data,

"said Ali Yetisen, a Phd candidate in the Department of Chemical engineering & Biotechnology, who led the research.

That s just what a group of MIT researchers have done in a new study published in the journal Nature Biotechnology.

Genetic engineering and Biotechnology News explains: The team began studying reflectin to discern how it enables the squid to change color

Church also is cofounder of the biotech firm Editas Medicine. He said he expects the company will enter clinical trials next year on a gene-editing process for humans e

and involved a collaboration between three universities and a biotech company. Both groups designed artificial versions of antibodies, the Y-shaped molecules made by the immune system to target pathogens.

Professor Shin'ichi Ishiwata (Graduate school of Advanced Science and Engineering) and Research Assistant Makito Miyazaki's (Research Institute for Science and Engineering) research team at the Waseda Bioscience Research Institute

"said Liang Xu, associate professor of molecular biosciences and corresponding author of the paper. The results hold promise for treating a broad array of cancers in people.

The study, funded by the Engineering and Physical sciences Research Council and the Biotechnology and Biological sciences Research Council, is published in Proceedings of the National Academy of Sciences.

MIT is negotiating an exclusive license agreement with Lyndra, an early-stage biotechnology company developing novel oral drug-delivery systems,

a professor of biotechnology and bioengineering at The swiss Federal Institute of technology in Zurich, described this experiment as an legant proof of conceptthat could lead to greatly improved treatments for viral infection. entinel designer cells engineered with the DNA sense

These findings could one day lead to super-dense low-power circuits as well as ultra-sensitive biosensors and gas sensors, the investigators added.

and ultra-sensitive and low-power biosensors and gas sensors to enhance the Internet of things. However, Banerjee cautions that TFETS are designed not for speed

Most tech innovation in agriculture was concentrated narrowly in biotechnology and seed genetics, and both investment and innovation was limited to players with close ties to the ag sector.

and the sector is described often as being more horizontal than vertical (we tracked 16 subcategoriess diverse as biotech,

and plant trait company Arcadia Biosciences recently filed a $86 million IPO. And in what might seem like a jump-the-shark moment while still in the first inning

and the biopharmaceutical company Metabolic Solutions Development Co. The company is involved in clinical trials that are evaluating the drug compound MSDC-0602 as a treatment for diabetes.

"said Ghodbane, who now works in biopharmaceutical research and development at Glaxosmithkline. The breakthrough also requires one-tenth of the chemicals used in a conventional multiplex immunoassay,

#Oxman Revolutionizes Biomanufacturing with Living, 3d Printed Wearable If a Makerbot Replicator 3d printer can be used in pharmacological research labs for advances studies on how to administer cancer fighting drugs,

and physical bioscientist Peter Zwart have introduced new mathematical theory and an algorithm, which they call ulti-tiered iterative phasing (M-TIP),

who is a member of the Physical Biosciences Division at Berkeley Lab. lthough fluctuation scattering was proposed first 38 years ago,

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