The third group was placed on a high-fat diet while the fourth group was the control. In collaboration with the Clinical and Translational Science Institute (CTSI) at Boston University the researchers performed genome-wide microarray profiling
or a high-fat diet may cause atherosclerotic plaques to undergo changes which affect their size and stability and may ultimately lead to a heart attack she added d
Drugs that flip this switch rapidly reduced obesity and diabetes risk factors in mice fed a high fat diet.
The drugs also significantly reduced the negative effects of a high-fat diet in mice, including reducing weight gain and, to the researcherssurprise,
Normally, mice fed a high fat diet for 45 days quickly balloon to nearly 160 percent of their starting weight.
normal rats insulin-resistant rats fed a high-fat diet and rats with genetically modified insulin receptors.
"The mice had been on a high-fat diet for three months and were already showing evidence of organ dysfunction,
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