Individually optimized nutrition for the smallest patients. Currently the only way to determine if premature newborns are malnourished is to monitor their growth rate.
He says that teaching patients to eat whole grains is still challenging but that encouraging the increase of fiber gradually as well as drinking adequate amounts of water are other practical recommendations.
and Europe usually cause problems only in people with suppressed immune systems such as AIDS patients or transplant recipients although some atypical North american and European strains have been associated with severe ocular toxoplasmosis.
For the first time we have used human stem cells derived from Parkinson's disease patients to show that a genetic mutation combined with exposure to pesticides creates a'double hit'scenario producing free radicals in neurons that disable specific molecular pathways that cause nerve-cell death
Research and professor of biology at the Massachusetts institute of technology (MIT) used skin cells from Parkinson's patients that had a mutation in the gene encoding a protein called alpha-synuclein.
Moreover we will be able to screen for patients who may benefit from a specific therapy that can prevent treat
and analyzed in patients with autism. Researchers in Cedars-Sinai's Department of Neurosurgery and Department of Neurology with colleagues from the California Institute of technology and Huntington Memorial Hospital in Pasadena listened in
and recorded the firing activity of individual nerve cells in the amygdalae of two patients with a high-functioning form of autism as they viewed pictures of entire faces or parts of faces on a screen.
or happiness--and the patients were asked to look at the pictures to decide which emotion was expressed.
The research team then compared recordings from neurons in the patients with autism to recordings from neurons in patients who did not have led autism
In the two patients with autism whole-face neurons responded appropriately but the face-part neurons were much more active
when the patients were shown the mouth region compared to when they were shown the eyes. A subpopulation of neurons in these patients with autism spectrum disorder showed abnormal sensitivity to the mouth region.
The amygdala neurons appeared normal from an electrical point of view and the whole-face-sensitive neurons responded normally.
The autism study was made possible by patients being treated for epilepsy who underwent surgery to have implanted depth electrodes in their brains to monitor seizure-related electrical activity.
Two of the patients also suffered from a high-functioning form of autism spectrum disorder. The amygdala is a routine target for depth electrodes to localize epileptic seizures.
In one they recorded the activity of single neurons as patients'brains processed cues from facial expressions.
and neck cancer patients Ray said she and her team would need to validate their results with other preclinical models.
During this test patients are fed tiny amounts of the suspected allergy-causing food in increasing doses under strict supervision by an allergist.
When patients with oral allergy syndrome take angiotensin-converting enzyme (ACE) inhibitors for hypertension and congestive heart failure they are increased at an risk for a life-threatening allergic reaction known as anaphylaxis according to new research.
and often patients can eat that food when it is cooked. For example an individual may have a reaction to a raw apple but not to apples baked in a pie.
When allergists advised patients to avoid raw produce and switched from ACE inhibitors to ANGIOTENSIN II receptor blocker (ARB) therapy no further oral allergy symptoms occurred.
#Collaborative efforts help mental health patients quit smokingpersons with mental illness account for more than one-third of adult smokers in the United states
and despite a decline in tobacco use during the past five decades there has been no change in the smoking rate for patients with poor mental health.
Historically mental health care has operated separately from general medical practices where collaborations exist to strongly encourage smoking cessation in typical patient populations said Jill M. Williams MD professor of psychiatry at Rutgers Robert Wood Johnson Medical school.
In a Viewpoint piece published Online First on October 30 in the Journal of the American Medical Association Psychiatry Williams said partnerships between mental health providers and state or county tobacco control programs benefit patients
For patients smoking cessation improves their health by reducing the impact of smoking-related illnesses.
In the Viewpoint piece Williams along with Jeffrey G. Willet Phd from Kansas Health Foundation and Gregory Miller MD MBA from the New york state Office of Mental health underscore the benefits to patients noting that collaborative
and encourages mental health providers to promote tobacco quit programs during face-to-face interactions with patients.
In clinics pathogenic fungi resistant to antifungal drugs are a major cause of mortality in patients.
Patients with non-celiac wheat sensitivity (NCWS) and other food sensitivities showed clinical laboratory and histological characteristics suggesting they may be suffering from a non-Ige-mediated food allergy according to the article Non-Celiac Wheat Sensitivity as an Allergic Condition:
and other relevant medical literature focusing on NCWS patients who may suffer from non-Ige-mediated wheat allergy.
and his colleagues reviewed data on 276 patients diagnosed with NCWS using a double-blind placebo-controlled wheat challenge.
The authors hypothesize that patients with NCWS may be suffering from non-Ige mediated food allergy.
We compared patients suffering from NCSW and irritable bowel syndrome (IBS) to controls with IBS not due to NCWS.
This is now considered a crucial element in IBS pathogenesis. Future studies in NCWS patients should consider the role of diet in the microbiota and in turn on the intestinal immune system Dr. Carroccio added.
For Birt-Hogg-Dub syndrome patients and their families better understanding of FCLN's function moves the field one step closer to developing a therapy.
which is a very important discovery for these patients. Story Source: The above story is provided based on materials by Whitehead Institute for Biomedical Research.
improve caredoctors commonly tell patients that stress can be harmful to their health. Yet when it comes to reducing their own stress levels physicians don't heed always their own advice.
and compassion for patients and increase the likelihood of medical errors said William Mccann Psy.
to help familiarize future doctors with techniques recommended in many medical treatment plans for patients;
Published in the journal Gastroenterology the study describes the pain mechanism of action for Linaclotide a recently approved drug for the treatment of chronic abdominal pain and constipation in adult IBS-C patients.
Approximately one third of IBS patients are diagnosed as having IBS-C. This is a significant finding
Abdominal pain is often the most troubling symptom to IBS patients and has been the most difficult symptom to treat.
and is already available and registered for use by IBS-C patients in the USA and Europe.
IBS-C patients given the drug orally showed significant improvement in abdominal pain over those given placebo during a 26-week trial.
which may decrease considerably patients'quality of life. Although its prevalence has been increasing over the last 40 years in many countries no statistical
and platelets--side effects often seen in patients undergoing radiation treatment for cancer. Rosen says this study points to two potential uses of the compound.
DIM could protect normal tissues in patients receiving radiation therapy for cancer but could also protect individuals from the lethal consequences of a nuclear disaster.
or when the patient is undernourished or dehydrated and in the case of chronic infections and renal or hepatic diseases.
But a new Duke university study says it can link what is in a patient's urine to gene mutations that cause retinitis pigmentosa or RP an inherited degenerative disease that results in severe vision impairment and often blindness.
This mutation appears to be prevalent in RP patients of the Ashkenazi Jewish origin and 1 in 322 Ashkenazi carries one copy of the mutation.
I knew from my previous experience in analyzing urine samples from liver disease patients that I can readily detect dolichols by liquid chromatography
Guan and his collaborators hope to develop the dolichol profiling method as a first-line diagnostic test to identify RP patients with abnormal dolichol metabolism.
They think this mass spectrometry-based detection method will help physicians provide more personalized care to RP patients especially to young children whose retinal degeneration has developed not fully.
We are now researching ways to manipulate the dolichol synthesis pathway in RP patients with the DHDDS mutation
The 280 patients in the phase two clinical trial for the grass allergy treatment recorded their allergy symptoms
During the clinical trial for the dust mite treatment 172 patients who received four doses of the treatment over 12 weeks had improved significantly allergy symptoms a year after the start of treatment compared to patients who received a placebo.
The discovery in the October edition of the journal Infection and Immunity may inform changes in the ways doctors treat patients.
In patients with H. pylori-associated gastritis higher numbers of cytotoxic T cells are present indicating that these cells may contribute to the development of gastric lesions.
In immunosuppressed people or hospitalized patients MRSA can lead to serious infections. As in previous years the number of hospital acquired cases continued to be very low:
and patients are asked about contact to pigs when admitted to hospital. Follow-up on the effect of treatment on otherwise healthy MRSA carriers has also been tightened up.
For the study researchers utilized Geisinger's sophisticated electronic health record system to identify patients with MRSA infections and skin and soft tissue infections.
The two groups were compared to patients who never had a MRSA infection. Patients received an exposure score based on their distance from the production the number of animals at livestock operations the amount of manure spread on crop fields and the size of the field.
The researchers noted that between 2005 and 2010 there were about 3000 patients with MRSA and 50000 with skin and soft tissue infections who were diagnosed
and treated in the Geisinger Health System. Of these cases 1539 cases of community-associated MRSA and 1335 cases of health-care-associated MRSA met the study requirements.
Most of the patients have been seizure-free since having the surgery while a few have experienced only isolated episodes.
and most patients can go home the next day. Based on what we've seen so far it's at least as effective as open surgery is far superior in terms of risk
But most people with epilepsy don't need surgery as seizures can be controlled by medication in approximately 60 percent of all patients.
Dr. Dickinson's research currently focuses on how sulforaphane--a naturally occurring compound in broccoli with established chemopreventive properties--could possibly be used to help patients reduce their risk for skin cancer.
Instead of eating broccoli to unlock the risk-reduction nutrients she's asking patients to apply small doses of sulforaphane to their skin.
Her pilot study in collaboration with Johns hopkins university will test a topical broccoli sprout solution on the skin a group of patients to see
Someday patients with compromised immune systems may be able to apply sulforaphane to their skin in order to reduce their risk of skin cancer.
Researchers from the School of Biological sciences and Norwich Medical school are now embarking on a small scale trial in osteoarthritis patients due to have knee replacement surgery to see
For the small scale trial funded by DRINC half the 40 patients will be given'super broccoli'--bred to be high in sulforaphane--to eat for two weeks before their operation.
but prolonging the lives of patients would be a significant development Johnson added. It is the fourth leading cause of cancer-related deaths with a five-year survival rate of only 6 percent she said.
Pancreatic cancer patients would probably not be able to eat enough flavonoid-rich foods to raise blood plasma levels of the flavonoid to an effective level.
#Psychiatric patients given smoking-cessation treatment less likely to be participated rehospitalizedpatients who in a smoking-cessation program during hospitalization for mental illness were able to quit smoking
The findings counter a longstanding assumption held by many mental-health experts that smoking serves as a useful tool in treating some psychiatric patients.
Smoking among such patients has been embedded in the culture for decades with cigarettes used as part of a reward system.
Indeed clinicians sometimes smoke alongside patients as a way of creating a rapport with them said Judith Prochaska Phd MPH associate professor of medicine at the Stanford Prevention Research center
The result is that psychiatric patients are among the country's most prolific smokers and among those most likely to die of smoking-related ailments Prochaska said.
if these patients quit smoking it would be detrimental to their recovery--that they would lose a critical crutch for coping with stress.
and that mental-health providers are equipped well to assist patients with developing healthier forms of coping.
and the use of nicotine patches could support rather than harm the patients'mental health she said.
This is a very low-cost brief intervention that helped patients quit smoking and offers evidence that it may have helped their mental health recovery said Prochaska who focuses on developing interventions to treat tobacco dependence in people with mental illness or addictive disorders.
She said the study done in collaboration with researchers at UC-San francisco is the first to examine the impact of a stop-smoking intervention in adult psychiatric patients.
that evidence-based tobacco dependence treatments can substantially increase quit rates among psychiatric inpatients. We know that psychiatric patients smoke at very high rates
and are at tremendous risk from their smoking. Thus the findings hold promise to make an important real-world contribution to the health of these patients.
Since 1993 tobacco use in U s. hospitals has been banned with the exception of inpatient psychiatry units
which can and often do permit smoking and where staff may smoke with patients. Prochaska regularly gives talks in
which she documents the long history of tobacco in psychiatry sharing excerpts from a 1951 psychotherapy handbook that encourages practitioners to smoke during treatment sessions.
Her work also has highlighted how the tobacco industry has sponsored research to promote the self-medication hypothesis--that patients with psychiatric disorders need to smoke to function
--and marketed their products to patients with psychiatric disorders. Tobacco use has been thought to help calm patients
and enable them to focus in therapy she said. Certainly a cigarette will calm someone who is in a state of nicotine withdrawal
and in hospitals that structure smoking breaks every four hours the patients are being thrown into repeated withdrawal states that are uncomfortable and stressful.
Some patients may appear more alert and attentive simply because the tobacco smoke is reducing the sedating side effects of their psychiatric medications she said.
To test the effects of treating tobacco use among hospitalized psychiatric patients the researchers initiated an intervention among 224 patients at the Langley Porter Psychiatric Institute a smoke-free locked mental hospital for acute care at UCSF.
All patients who smoked at least five cigarettes daily prior to hospitalization were invited to participate. Few were ready to quit smoking yet 79 percent agreed to participate.
The patients had a range of psychiatric diagnoses including depression bipolar disorder and schizophrenia; three in four were actively suicidal.
All patients were offered nicotine patches or gum during their smoke-free hospitalization. Patients in the control group received a pamphlet about the hazards of smoking with information on how to quit.
Participants in the treatment group completed a computer-assisted program with tailored feedback received a print manual met for 15-30 minutes with a counselor
All of the materials were tailored to patients'readiness to quit and the computer-assisted intervention was repeated at three and six months post-hospitalization to support participants through the process of quitting smoking.
A copy of the computer printout was mailed to patients'outpatient providers. A key aspect of the intervention is did that we not assume all patients were ready to quit Prochaska said.
We met them where they were worked at and with them over time. When they became ready to quit we were there for them
Only a small number of patients--16 percent--initially said they were prepared to quit when they enrolled in the study
But at a minimum she added treating patients'smoking did not harm their mental health recovery
The patients'diagnoses and the severity of their symptoms had no impact on intervention outcomes the researchers found.
Assumptions we have made in the field--that these patients don't want to quit are too ill to quit
What did influence outcomes were patients'perceptions at the study start of how successful they would be with quitting
If we wonder in our field why our patients smoke at such high rates we have to start by looking at how we've addressed tobacco.
Prochaska and her colleagues are now following up with a larger trial involving more than 900 patients at Stanford Hospital & Clinics Alta Bates Summit Medical center in Berkeley and UCSF's Langley Porter.
#Healthy diet, moderate alcohol linked with decreased risk of kidney disease in patient with diabeteseating a healthy diet
or progression of chronic kidney disease (CKD) in patients with type 2 diabetes mellitus according to a report published by JAMA Internal medicine a JAMA Network publication.
Daniela Dunkler Ph d. of Mcmaster University Ontario Canada and colleagues examined the association of a healthy diet alcohol protein and sodium intake with incident or progression of CKD among patients with type
All 6213 patients with type 2 diabetes in the ONTARGET trial were included in the observational study.
The study results indicate that 31.7 percent of patients developed CKD and 8. 3 percent of patients died after 5. 5 years of follow-up.
Compared with patients in the least healthy scoring group on an index that assessed diet quality patients in the healthiest group had a lower risk of CKD (adjusted odds ratio OR 0. 74) and lower risk of mortality
(OR 0. 61. Patients who ate more than three servings of fruits per week had a lower risk of CKD compared with patients who ate fruit less frequently.
Patients in the lowest group of total and animal protein intake had increased an risk of CKD compared with patients in the highest group.
Sodium intake was associated not with CKD while moderate alcohol intake reduced the risk of CKD (OR 0. 75) and mortality (OR 0. 69).
Patients with both type 2 diabetes and kidney disease may be frustrated by the numerous dietary restrictions that are recommended by their health care team.
Patients may even ask 'what can I eat?''Perhaps the best dietary advice we can give to patients with type 2 diabetes
and kidney disease is the same as the advice for those who want to avoid chronic kidney disease
Currently no definite evidence indicates sustained human-to-human transmission of the H7n9 virus. The study reports a family cluster of two patients (father and daughter) with H7n9 virus infection in Eastern China in March 2013.
The first (index) patient--a 60 year old man--regularly visited a live poultry market and became ill five to six days after his last exposure to poultry.
The second patient his healthy 32 year old daughter had known no exposure to live poultry before becoming sick.
Two almost genetically identical virus strains were isolated from each patient suggesting transmission from father to daughter.
but was genetically different to the two strains isolated from the patients. The researchers acknowledge some study limitations
but say that the most likely explanation for this family cluster of two cases with H7n9 infection is that the virus transmitted directly from the index patient to his daughter.
But Veterinarian David Burch argues that medicated animal feed poses no additional risk of resistance development than giving a human patient an oral antimicrobial.
but says given the thorough risk assessments concerning antimicrobial resistance by the regulatory authorities it is considered highly unlikely that the use of adding antibiotics to feed poses a serious risk to humans especially in comparison with the extensive use of antibiotics directly in human patients.
when we need to like for a patient who has one of the protein folding diseases he said.
when we need to like for a patient who has one of the protein folding diseases he said.
However the contribution of multidrug resistance to limited or failed therapy in veterinary patients has received much less attention.
High levels of insulin can signal that a patient has diabetes. The cocoa powder supplement also reduced the levels of liver triglycerides in mice by a little more than 32 percent according to Lambert who worked with Yeyi Gu graduate student in food science and Shan Yu a graduate student in physiology.
Research at other institutions has shown that meditation can significantly reduce anxiety in patients with generalized anxiety and depression disorders.
Time and time again we hear from patients that they never felt depressed or anxious until they started experiencing problems with their gut Tillisch said.
and the doctor-patient relationship and even a patient's willingness or desire to go see their physician so it is crucial that we try to deal with any bias during medical school said David Miller M d. associate professor of internal medicine at Wake Forest Baptist
and they are less likely to respect obese patients than average weight patients Miller said.
and we believe they are less toxic for patients result in less biohazardous waste for the environment
The therapeutic potential of grapefruit derived nanoparticles was validated further through a Phase 1 clinical trial for treatment of colon cancer patients.
So far researchers have observed no toxicity in the patients who orally took the anti-inflammatory agent curcumin encapsulated in grapefruit nanoparticles.
and case series of patients with similar disease or health profiles said study lead author Carlos Torres-Duque M d. director of research at the Fundacion Neumologica Colombiana in Bogota.
Patients'lung function was measured using spirometry a technique used to measure the amount of air a person is able to inhale
and exhale and all patients completed a standardized respiratory questionnaire to identify exposure to smoke.
On surveillance in the war against cancerpredicting outcomes for cancer patients based on tumor-immune system interactions is an emerging clinical approach
Strikingly the patients who seemed to benefit the most were those with highly proliferative and clinically aggressive disease Miller said.
and colleagues from the University of Washington in Seattle recruited 490 patients newly diagnosed with Parkinson's disease at the university's Neurology Clinic or a regional health maintenance organization Group Health Cooperative.
and increase patients'survival rates. Story Source: The above story is provided based on materials by Plataforma SINC.
He suggests that we should be tracking pesticides use in the environment just like we monitor drug use in patients.
At the same time patients consumed plenty of leafy greens shellfish and fish olive oil and grass-fed animal protein
or even saliva test that measures genotype Dr. John Kostis said They can compare the patient's genetic background with the polymorphisms that have been identified in the study
and counsel patients accordingly offering advice as to which type of intervention may be more successful in lowering that patient's blood pressure he said.
With genomic studies becoming more widespread and less expensive evaluating weight sensitivity may be one way to identify individuals who may benefit more from weight loss as compared with other types of lifestyle interventions like cutting salt from their diet Dr. William Kostis said.
and glucose was considered promising by doctors who prescribed them for patients with metabolic syndrome--a collection of risk factors linked to heart disease
In diagnosing cancer nanoparticles with cancer-seeking properties might be injected into a patient before a medical scan.
and the manufacture of a synthetic form of psilocybin for use in patients is controlled tightly by EU regulations.
The proposed trial will be for patients with depression who have failed two previous treatments for the condition.
Thirty patients will be given a synthetic form of psilocybin and 30 patients will be given a placebo. The drug (or placebo) will be given during two possibly three carefully controlled
and prepared 30-60 minute sessions. The first session will be a low dose to check there are no adverse responses the second session will give a higher therapeutic dose
and then patients can have a third booster dose in a later session if it's considered necessary.
While they are under the influence of the drug the patients will have guided talking therapy to enable them to explore their negative thinking
The doctors will follow up the patients for at least a year. What we are trying to do is to tap into the reservoir of under-researched'illegal'drugs to see
and for the last 40 years we have missed really interesting opportunities to help patients. Ethical approval for the trial was granted in March
Food-grade sorghums should be considered as an important option for all people especially celiac patients the report concluded.
and identify cancerous cells in the bloodstream which would provide the diagnostic information needed to create individually tailored treatments for patients with prostate cancer.
and that every patient's cancer is a unique problem--the'one-size-fits-all'approach is not going to allow us to cure prostate cancer
and to ensure a patient's treatment is individualized and optimized. The molecular characterizations of CTCS will provide real-time information allowing us to choose the right treatment for the right patient at the right time.
This improvement will be a great step toward developing personalized medicine he added. The existence of CTCS and their role in cancer metastasis was suspected first more than 140 years ago
and will allow us to better understand the mechanism of drug resistance that is common in prostate cancer patients.
We hope the comprehensive understanding of cancer biology at the individual level will ultimately lead to better therapy choice for patients suffering from advanced cancer.
With the new system a patient's blood is pumped through the Nanovelcro Chip--the microvilli protruding from the cancer cells will stick to the nanofiber structures on the device's surface much like Velcro.
and may help doctors personalize therapies to a patient's unique cancer. To date CTC capture technologies have been able to do little more than count the number of CTCS which is informative but not very useful from a treatment planning perspective.
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